RBP Type	Canonical_RBPs
Diseases	Cancer Disease
Drug	N.A.
Main interacting RNAs	mRNA
Moonlighting functions	E3 ligase
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000179455	Gene ID	7681	Accession	7114
Symbol	MKRN3	Alias	CPPB2;D15S9;RNF63;ZFP127;ZNF127	Full Name	makorin ring finger protein 3
Status	Confidence	Length	64402 bases	Strand	Plus strand
Position	15 : 23565674 - 23630075	RNA binding domain	zf-CCCH_2
Summary	The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene. [provided by RefSeq, Jul 2008]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000313881	zf-CCCH_2	PF14608	2.2e-09	1
ENSP00000313881	zf-CCCH_2	PF14608	2.2e-09	2
ENSP00000313881	zf-CCCH_2	PF14608	2.2e-09	3
ENSP00000503032	zf-CCCH_2	PF14608	5.4e-05	1
ENSP00000503032	zf-CCCH_2	PF14608	5.4e-05	2
ENSP00000502884	zf-CCCH_2	PF14608	6.4e-05	1
ENSP00000502884	zf-CCCH_2	PF14608	6.4e-05	2

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
35928377	Genetic causes of central precocious puberty.	Toshihiro Tajima	2022-01-01	Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology
27462581	An update on the genetic causes of central precocious puberty.	Young-Lim Shin	2016-06-01	Annals of pediatric endocrinology & metabolism
36619551	Genetic, epigenetic and enviromental influencing factors on the regulation of precocious and delayed puberty.	Felicia Maria Faienza	2022-01-01	Frontiers in endocrinology
37092553	MKRN3 inhibits puberty onset via interaction with IGF2BP1 and regulation of hypothalamic plasticity.	Lydie Naulé	2023-04-24	JCI insight
32984644	Makorin RING finger protein 3 and central precocious puberty.	Luigi Maione	2020-10-01	Current opinion in endocrine and metabolic research
31636607	Central Precocious Puberty Caused by Novel Mutations in the Promoter and 5'-UTR Region of the Imprinted MKRN3 Gene.	Pavlos Fanis	2019-01-01	Frontiers in endocrinology
25316453	A novel MKRN3 missense mutation causing familial precocious puberty.	L L de	2014-12-01	Human reproduction (Oxford, England)

Name	Transcript ID	bp	Protein	Translation ID
MKRN3-201	ENST00000314520	2371	507aa	ENSP00000313881
MKRN3-212	ENST00000679144	2490	102aa	ENSP00000504844
MKRN3-202	ENST00000564592	2091	182aa	ENSP00000455368
MKRN3-209	ENST00000677119	1914	123aa	ENSP00000503815
MKRN3-205	ENST00000570112	470	No protein	-
MKRN3-206	ENST00000647595	923	38aa	ENSP00000496869
MKRN3-203	ENST00000568252	1312	105aa	ENSP00000456779
MKRN3-207	ENST00000649065	2545	161aa	ENSP00000496859
MKRN3-211	ENST00000678440	2094	320aa	ENSP00000503032
MKRN3-208	ENST00000676568	1601	330aa	ENSP00000502884
MKRN3-204	ENST00000568945	2740	96aa	ENSP00000497232
MKRN3-210	ENST00000677372	1615	94aa	ENSP00000503024

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
20136	Uric Acid	5.682e-005	-
20144	Uric Acid	5.658e-005	-
34323	Smoking	1.2700000E-005	-
75600	Immunoglobulins	4E-6	23382691

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000179455	homo_sapiens	ENSP00000255977	63.9004	50.4149	homo_sapiens	ENSP00000313881	60.7495	47.929
ENSG00000179455	homo_sapiens	ENSP00000170447	48.5577	34.1346	homo_sapiens	ENSP00000313881	39.8422	28.0079

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000179455	homo_sapiens	ENSP00000313881	33.5306	31.3609	nomascus_leucogenys	ENSNLEP00000033893	93.4066	87.3626
ENSG00000179455	homo_sapiens	ENSP00000313881	33.925	32.5444	pan_paniscus	ENSPPAP00000020373	94.5055	90.6593
ENSG00000179455	homo_sapiens	ENSP00000313881	33.5306	31.9527	pongo_abelii	ENSPPYP00000039116	94.9721	90.5028
ENSG00000179455	homo_sapiens	ENSP00000313881	33.925	32.5444	pan_troglodytes	ENSPTRP00000065723	94.5055	90.6593
ENSG00000179455	homo_sapiens	ENSP00000313881	33.925	32.5444	gorilla_gorilla	ENSGGOP00000029771	94.5055	90.6593
ENSG00000179455	homo_sapiens	ENSP00000313881	55.6213	44.3787	ornithorhynchus_anatinus	ENSOANP00000041325	45.3376	36.1736
ENSG00000179455	homo_sapiens	ENSP00000313881	60.355	47.929	sarcophilus_harrisii	ENSSHAP00000038365	64.0167	50.8368
ENSG00000179455	homo_sapiens	ENSP00000313881	60.1578	47.7318	notamacropus_eugenii	ENSMEUP00000006753	63.8075	50.6276
ENSG00000179455	homo_sapiens	ENSP00000313881	76.5286	67.8501	choloepus_hoffmanni	ENSCHOP00000004333	79.6715	70.6366
ENSG00000179455	homo_sapiens	ENSP00000313881	35.1085	29.5858	dasypus_novemcinctus	ENSDNOP00000026998	71.2	60
ENSG00000179455	homo_sapiens	ENSP00000313881	76.9231	68.0473	dasypus_novemcinctus	ENSDNOP00000004046	79.1075	69.9797
ENSG00000179455	homo_sapiens	ENSP00000313881	66.075	57.5937	erinaceus_europaeus	ENSEEUP00000007395	69.3582	60.4555
ENSG00000179455	homo_sapiens	ENSP00000313881	32.9389	30.7692	callithrix_jacchus	ENSCJAP00000065456	91.7582	85.7143
ENSG00000179455	homo_sapiens	ENSP00000313881	32.3471	29.9803	cercocebus_atys	ENSCATP00000022163	90.1099	83.5165
ENSG00000179455	homo_sapiens	ENSP00000313881	33.1361	30.7692	macaca_fascicularis	ENSMFAP00000049571	78.1395	72.5581
ENSG00000179455	homo_sapiens	ENSP00000313881	33.5306	30.3748	macaca_mulatta	ENSMMUP00000043415	87.6289	79.3814
ENSG00000179455	homo_sapiens	ENSP00000313881	32.1499	29.783	macaca_nemestrina	ENSMNEP00000008746	89.5604	82.967
ENSG00000179455	homo_sapiens	ENSP00000313881	32.3471	29.9803	papio_anubis	ENSPANP00000028427	90.1099	83.5165
ENSG00000179455	homo_sapiens	ENSP00000313881	32.3471	29.9803	mandrillus_leucophaeus	ENSMLEP00000001670	90.1099	83.5165
ENSG00000179455	homo_sapiens	ENSP00000313881	76.7258	68.4418	mus_spretus	MGP_SPRETEiJ_P0083256	71.7712	64.0221
ENSG00000179455	homo_sapiens	ENSP00000313881	71.9921	62.9191	capra_hircus	ENSCHIP00000023155	76.0417	66.4583
ENSG00000179455	homo_sapiens	ENSP00000313881	63.5108	52.2682	loxodonta_africana	ENSLAFP00000024806	70.7692	58.2418
ENSG00000179455	homo_sapiens	ENSP00000313881	75.9369	67.6529	panthera_leo	ENSPLOP00000004702	77.9352	69.4332
ENSG00000179455	homo_sapiens	ENSP00000313881	76.9231	68.8363	ailuropoda_melanoleuca	ENSAMEP00000013162	77.381	69.246
ENSG00000179455	homo_sapiens	ENSP00000313881	71.4004	62.3274	bos_indicus_hybrid	ENSBIXP00005022944	76.2105	66.5263
ENSG00000179455	homo_sapiens	ENSP00000313881	85.2071	76.1341	oryctolagus_cuniculus	ENSOCUP00000011035	83.8835	74.9515
ENSG00000179455	homo_sapiens	ENSP00000313881	72.5838	64.497	canis_lupus_familiaris	ENSCAFP00845027267	71.5953	63.6187
ENSG00000179455	homo_sapiens	ENSP00000313881	75.9369	67.6529	panthera_pardus	ENSPPRP00000027514	77.9352	69.4332
ENSG00000179455	homo_sapiens	ENSP00000313881	76.9231	70.0197	marmota_marmota_marmota	ENSMMMP00000021756	77.381	70.4365
ENSG00000179455	homo_sapiens	ENSP00000313881	67.0611	60.5523	felis_catus	ENSFCAP00000060257	78.5219	70.9007
ENSG00000179455	homo_sapiens	ENSP00000313881	33.5306	30.1775	monodon_monoceros	ENSMMNP00015015844	67.7291	60.9562
ENSG00000179455	homo_sapiens	ENSP00000313881	47.7318	41.0256	sus_scrofa	ENSSSCP00000005206	63.8522	54.8813
ENSG00000179455	homo_sapiens	ENSP00000313881	79.4872	70.0197	jaculus_jaculus	ENSJJAP00000003738	79.0196	69.6078
ENSG00000179455	homo_sapiens	ENSP00000313881	59.3688	49.9014	physeter_catodon	ENSPCTP00005012268	74.8756	62.9353
ENSG00000179455	homo_sapiens	ENSP00000313881	77.3176	69.2308	mus_caroli	MGP_CAROLIEiJ_P0079910	71.7949	64.2857
ENSG00000179455	homo_sapiens	ENSP00000313881	76.9231	68.6391	mus_musculus	ENSMUSP00000091898	71.6912	63.9706
ENSG00000179455	homo_sapiens	ENSP00000313881	72.7811	64.2998	dipodomys_ordii	ENSDORP00000021721	63.6207	56.2069
ENSG00000179455	homo_sapiens	ENSP00000313881	71.9921	65.8777	mustela_putorius_furo	ENSMPUP00000014525	77.9915	71.3675
ENSG00000179455	homo_sapiens	ENSP00000313881	32.9389	30.9665	aotus_nancymaae	ENSANAP00000024098	91.7582	86.2637
ENSG00000179455	homo_sapiens	ENSP00000313881	32.3471	30.1775	saimiri_boliviensis_boliviensis	ENSSBOP00000000870	89.6175	83.6066
ENSG00000179455	homo_sapiens	ENSP00000313881	64.1026	55.6213	vicugna_pacos	ENSVPAP00000003641	77.0142	66.8246
ENSG00000179455	homo_sapiens	ENSP00000313881	97.4359	95.2663	chlorocebus_sabaeus	ENSCSAP00000018387	97.4359	95.2663
ENSG00000179455	homo_sapiens	ENSP00000313881	71.0059	62.1302	mesocricetus_auratus	ENSMAUP00000017227	65.9341	57.6923
ENSG00000179455	homo_sapiens	ENSP00000313881	71.4004	62.7219	camelus_dromedarius	ENSCDRP00005005533	72.4	63.6
ENSG00000179455	homo_sapiens	ENSP00000313881	25.8383	23.4714	carlito_syrichta	ENSTSYP00000021505	75.2874	68.3908
ENSG00000179455	homo_sapiens	ENSP00000313881	78.1065	69.2308	rattus_norvegicus	ENSRNOP00000013551	75	66.4773
ENSG00000179455	homo_sapiens	ENSP00000313881	76.5286	68.0473	microtus_ochrogaster	ENSMOCP00000001782	71.0623	63.1868
ENSG00000179455	homo_sapiens	ENSP00000313881	40.8284	33.5306	sorex_araneus	ENSSARP00000002650	73.4043	60.2837
ENSG00000179455	homo_sapiens	ENSP00000313881	74.5562	65.8777	peromyscus_maniculatus_bairdii	ENSPEMP00000008162	71.1864	62.9002
ENSG00000179455	homo_sapiens	ENSP00000313881	68.0473	60.9467	mus_spicilegus	ENSMSIP00000038586	75	67.1739
ENSG00000179455	homo_sapiens	ENSP00000313881	74.5562	65.8777	cricetulus_griseus_chok1gshd	ENSCGRP00001008311	72	63.619
ENSG00000179455	homo_sapiens	ENSP00000313881	46.1538	36.8836	myotis_lucifugus	ENSMLUP00000017670	62.4	49.8667
ENSG00000179455	homo_sapiens	ENSP00000313881	60.1578	47.5345	vombatus_ursinus	ENSVURP00010018773	63.8075	50.4184
ENSG00000179455	homo_sapiens	ENSP00000313881	74.7534	65.8777	rhinolophus_ferrumequinum	ENSRFEP00010027898	77.3469	68.1633
ENSG00000179455	homo_sapiens	ENSP00000313881	71.9921	62.7219	bos_taurus	ENSBTAP00000062131	76.2004	66.3883
ENSG00000179455	homo_sapiens	ENSP00000313881	32.1499	29.9803	rhinopithecus_bieti	ENSRBIP00000008988	89.5604	83.5165
ENSG00000179455	homo_sapiens	ENSP00000313881	72.5838	64.497	canis_lupus_dingo	ENSCAFP00020030842	71.5953	63.6187
ENSG00000179455	homo_sapiens	ENSP00000313881	78.501	71.5976	sciurus_vulgaris	ENSSVLP00005000153	78.9683	72.0238
ENSG00000179455	homo_sapiens	ENSP00000313881	30.3748	21.8935	phascolarctos_cinereus	ENSPCIP00000000493	54.0351	38.9474
ENSG00000179455	homo_sapiens	ENSP00000313881	69.0335	60.9467	procavia_capensis	ENSPCAP00000015672	72.6141	64.1079
ENSG00000179455	homo_sapiens	ENSP00000313881	78.6982	71.2032	nannospalax_galili	ENSNGAP00000004848	76.7308	69.4231
ENSG00000179455	homo_sapiens	ENSP00000313881	70.217	60.9467	bos_grunniens	ENSBGRP00000015072	76.7241	66.5948
ENSG00000179455	homo_sapiens	ENSP00000313881	69.0335	58.9744	chinchilla_lanigera	ENSCLAP00000015887	59.9315	51.1986
ENSG00000179455	homo_sapiens	ENSP00000313881	66.2722	58.5799	cervus_hanglu_yarkandensis	ENSCHYP00000008097	71.4894	63.1915
ENSG00000179455	homo_sapiens	ENSP00000313881	77.1203	69.2308	ictidomys_tridecemlineatus	ENSSTOP00000005440	76.3672	68.5547
ENSG00000179455	homo_sapiens	ENSP00000313881	66.6667	57.1992	otolemur_garnettii	ENSOGAP00000018226	65.8869	56.5302
ENSG00000179455	homo_sapiens	ENSP00000313881	32.5444	30.3748	cebus_imitator	ENSCCAP00000022031	90.6593	84.6154
ENSG00000179455	homo_sapiens	ENSP00000313881	24.6548	21.6963	urocitellus_parryii	ENSUPAP00010008674	67.5676	59.4595
ENSG00000179455	homo_sapiens	ENSP00000313881	71.7949	62.3274	moschus_moschiferus	ENSMMSP00000015970	72.8	63.2
ENSG00000179455	homo_sapiens	ENSP00000313881	32.1499	29.9803	rhinopithecus_roxellana	ENSRROP00000005342	89.5604	83.5165
ENSG00000179455	homo_sapiens	ENSP00000313881	76.3314	68.8363	mus_pahari	MGP_PahariEiJ_P0016768	70.8791	63.9194
ENSG00000179455	homo_sapiens	ENSP00000313881	52.4655	40.2367	callorhinchus_milii	ENSCMIP00000048288	56.9593	43.6831
ENSG00000179455	homo_sapiens	ENSP00000313881	49.9014	39.4477	latimeria_chalumnae	ENSLACP00000017308	61.8582	48.8998
ENSG00000179455	homo_sapiens	ENSP00000313881	52.6627	40.2367	lepisosteus_oculatus	ENSLOCP00000019877	60.5442	46.2585
ENSG00000179455	homo_sapiens	ENSP00000313881	52.071	39.4477	clupea_harengus	ENSCHAP00000059329	58.9286	44.6429
ENSG00000179455	homo_sapiens	ENSP00000313881	52.071	39.645	danio_rerio	ENSDARP00000061069	60.1367	45.7859
ENSG00000179455	homo_sapiens	ENSP00000313881	51.6765	38.856	carassius_auratus	ENSCARP00000049178	59.5455	44.7727
ENSG00000179455	homo_sapiens	ENSP00000313881	51.6765	38.6588	carassius_auratus	ENSCARP00000022239	58.8764	44.0449
ENSG00000179455	homo_sapiens	ENSP00000313881	52.2682	39.645	carassius_auratus	ENSCARP00000003563	60.5023	45.8904
ENSG00000179455	homo_sapiens	ENSP00000313881	51.0848	38.6588	astyanax_mexicanus	ENSAMXP00000029326	58.0718	43.9462
ENSG00000179455	homo_sapiens	ENSP00000313881	51.8738	39.2505	ictalurus_punctatus	ENSIPUP00000025087	57.2985	43.3551
ENSG00000179455	homo_sapiens	ENSP00000313881	50.0986	38.856	esox_lucius	ENSELUP00000033351	55.3377	42.9194
ENSG00000179455	homo_sapiens	ENSP00000313881	50.8876	38.2643	electrophorus_electricus	ENSEEEP00000037355	58.7699	44.1913
ENSG00000179455	homo_sapiens	ENSP00000313881	11.8343	9.07298	oncorhynchus_kisutch	ENSOKIP00005115173	40.5405	31.0811
ENSG00000179455	homo_sapiens	ENSP00000313881	30.7692	23.8659	oncorhynchus_kisutch	ENSOKIP00005102221	55.3191	42.9078
ENSG00000179455	homo_sapiens	ENSP00000313881	49.3097	37.2781	oncorhynchus_mykiss	ENSOMYP00000143403	44.5633	33.6898
ENSG00000179455	homo_sapiens	ENSP00000313881	49.3097	37.2781	oncorhynchus_mykiss	ENSOMYP00000122279	44.3262	33.5106
ENSG00000179455	homo_sapiens	ENSP00000313881	49.1124	36.8836	salmo_salar	ENSSSAP00000020321	54.1304	40.6522
ENSG00000179455	homo_sapiens	ENSP00000313881	42.0118	31.5582	salmo_salar	ENSSSAP00000147477	53.6524	40.3023
ENSG00000179455	homo_sapiens	ENSP00000313881	49.5069	37.0809	salmo_trutta	ENSSTUP00000078625	55.902	41.8708
ENSG00000179455	homo_sapiens	ENSP00000313881	50.6903	38.6588	gadus_morhua	ENSGMOP00000001769	57.8829	44.1441
ENSG00000179455	homo_sapiens	ENSP00000313881	49.9014	36.2919	fundulus_heteroclitus	ENSFHEP00000009867	53.6017	38.9831
ENSG00000179455	homo_sapiens	ENSP00000313881	52.071	38.2643	poecilia_reticulata	ENSPREP00000025992	60.4119	44.3936
ENSG00000179455	homo_sapiens	ENSP00000313881	48.7179	35.7002	xiphophorus_maculatus	ENSXMAP00000005106	60.2439	44.1463
ENSG00000179455	homo_sapiens	ENSP00000313881	50.8876	38.2643	oryzias_latipes	ENSORLP00000015988	55.6034	41.8103
ENSG00000179455	homo_sapiens	ENSP00000313881	51.8738	37.8698	cyclopterus_lumpus	ENSCLMP00005036451	61.0209	44.5476
ENSG00000179455	homo_sapiens	ENSP00000313881	50.8876	37.6726	oreochromis_niloticus	ENSONIP00000067321	52.439	38.8211
ENSG00000179455	homo_sapiens	ENSP00000313881	46.7456	32.9389	haplochromis_burtoni	ENSHBUP00000031938	60.9254	42.9306
ENSG00000179455	homo_sapiens	ENSP00000313881	52.071	38.6588	astatotilapia_calliptera	ENSACLP00000020441	61.2529	45.4756
ENSG00000179455	homo_sapiens	ENSP00000313881	51.0848	37.8698	sparus_aurata	ENSSAUP00010003446	50.0967	37.1373
ENSG00000179455	homo_sapiens	ENSP00000313881	51.8738	38.4615	lates_calcarifer	ENSLCAP00010028195	61.0209	45.2436
ENSG00000179455	homo_sapiens	ENSP00000313881	55.2268	41.6174	xenopus_tropicalis	ENSXETP00000114170	62.0843	46.7849
ENSG00000179455	homo_sapiens	ENSP00000313881	59.3688	46.5483	chrysemys_picta_bellii	ENSCPBP00000016134	64.3162	50.4273
ENSG00000179455	homo_sapiens	ENSP00000313881	56.6075	43.5897	sphenodon_punctatus	ENSSPUP00000005234	64.6396	49.7748
ENSG00000179455	homo_sapiens	ENSP00000313881	56.4103	43.5897	crocodylus_porosus	ENSCPRP00005025925	61.242	47.3233
ENSG00000179455	homo_sapiens	ENSP00000313881	54.2406	41.2229	laticauda_laticaudata	ENSLLTP00000020226	65.3207	49.6437
ENSG00000179455	homo_sapiens	ENSP00000313881	58.1854	44.5759	notechis_scutatus	ENSNSUP00000018705	60.6996	46.5021
ENSG00000179455	homo_sapiens	ENSP00000313881	57.9882	44.3787	pseudonaja_textilis	ENSPTXP00000010402	60.4938	46.2963
ENSG00000179455	homo_sapiens	ENSP00000313881	57.5937	44.9704	anas_platyrhynchos_platyrhynchos	ENSAPLP00000031305	58.1673	45.4183
ENSG00000179455	homo_sapiens	ENSP00000313881	57.1992	44.7732	gallus_gallus	ENSGALP00010018927	62.5	48.9224
ENSG00000179455	homo_sapiens	ENSP00000313881	51.4793	40.2367	meleagris_gallopavo	ENSMGAP00000028908	61.9953	48.4561
ENSG00000179455	homo_sapiens	ENSP00000313881	54.6351	42.8008	serinus_canaria	ENSSCAP00000013090	63.5321	49.7706
ENSG00000179455	homo_sapiens	ENSP00000313881	53.4517	41.0256	parus_major	ENSPMJP00000012193	58.2796	44.7312
ENSG00000179455	homo_sapiens	ENSP00000313881	58.1854	44.9704	anolis_carolinensis	ENSACAP00000010785	60.6996	46.9136
ENSG00000179455	homo_sapiens	ENSP00000313881	58.1854	44.5759	naja_naja	ENSNNAP00000026441	60.6996	46.5021
ENSG00000179455	homo_sapiens	ENSP00000313881	59.3688	45.7594	podarcis_muralis	ENSPMRP00000019879	60.5634	46.6801
ENSG00000179455	homo_sapiens	ENSP00000313881	55.0296	42.998	geospiza_fortis	ENSGFOP00000003017	66.1137	51.6588
ENSG00000179455	homo_sapiens	ENSP00000313881	58.1854	45.9566	taeniopygia_guttata	ENSTGUP00000031514	56.4054	44.5507
ENSG00000179455	homo_sapiens	ENSP00000313881	47.929	36.8836	erpetoichthys_calabaricus	ENSECRP00000004959	59.7052	45.9459
ENSG00000179455	homo_sapiens	ENSP00000313881	51.8738	38.856	kryptolebias_marmoratus	ENSKMAP00000014606	61.0209	45.7077
ENSG00000179455	homo_sapiens	ENSP00000313881	58.7771	44.5759	salvator_merianae	ENSSMRP00000020564	60.5691	45.935
ENSG00000179455	homo_sapiens	ENSP00000313881	49.7041	35.8974	oryzias_javanicus	ENSOJAP00000035201	58.3333	42.1296
ENSG00000179455	homo_sapiens	ENSP00000313881	49.7041	37.2781	amphilophus_citrinellus	ENSACIP00000027353	58.0645	43.5484
ENSG00000179455	homo_sapiens	ENSP00000313881	50.6903	37.0809	dicentrarchus_labrax	ENSDLAP00005015271	59.2166	43.318
ENSG00000179455	homo_sapiens	ENSP00000313881	51.8738	38.4615	amphiprion_percula	ENSAPEP00000001861	61.1628	45.3488
ENSG00000179455	homo_sapiens	ENSP00000313881	34.3195	25.4438	oryzias_sinensis	ENSOSIP00000010331	62.1429	46.0714
ENSG00000179455	homo_sapiens	ENSP00000313881	54.4379	42.0118	pelodiscus_sinensis	ENSPSIP00000009249	66.187	51.0791
ENSG00000179455	homo_sapiens	ENSP00000313881	59.9606	46.9428	gopherus_evgoodei	ENSGEVP00005013269	64.8188	50.7463
ENSG00000179455	homo_sapiens	ENSP00000313881	59.5661	46.5483	chelonoidis_abingdonii	ENSCABP00000030334	64.5299	50.4273
ENSG00000179455	homo_sapiens	ENSP00000313881	51.4793	38.0671	seriola_dumerili	ENSSDUP00000025558	60.5568	44.7796
ENSG00000179455	homo_sapiens	ENSP00000313881	51.0848	37.8698	cottoperca_gobio	ENSCGOP00000005711	54.8729	40.678
ENSG00000179455	homo_sapiens	ENSP00000313881	57.3965	44.5759	struthio_camelus_australis	ENSSCUP00000024140	55.4286	43.0476
ENSG00000179455	homo_sapiens	ENSP00000313881	57.5937	45.1677	anser_brachyrhynchus	ENSABRP00000005598	60.3306	47.314
ENSG00000179455	homo_sapiens	ENSP00000313881	49.9014	36.4892	gasterosteus_aculeatus	ENSGACP00000025415	58.0275	42.4312
ENSG00000179455	homo_sapiens	ENSP00000313881	48.9152	38.2643	cynoglossus_semilaevis	ENSCSEP00000025409	58.4906	45.7547
ENSG00000179455	homo_sapiens	ENSP00000313881	52.2682	38.4615	poecilia_formosa	ENSPFOP00000006654	60.6407	44.6224
ENSG00000179455	homo_sapiens	ENSP00000313881	51.4793	38.6588	myripristis_murdjan	ENSMMDP00005025062	57.3626	43.0769
ENSG00000179455	homo_sapiens	ENSP00000313881	52.071	38.6588	sander_lucioperca	ENSSLUP00000035668	61.2529	45.4756
ENSG00000179455	homo_sapiens	ENSP00000313881	57.5937	45.1677	strigops_habroptila	ENSSHBP00005014729	58.4	45.8
ENSG00000179455	homo_sapiens	ENSP00000313881	49.1124	36.6864	amphiprion_ocellaris	ENSAOCP00000023539	60	44.8193
ENSG00000179455	homo_sapiens	ENSP00000313881	59.3688	46.5483	terrapene_carolina_triunguis	ENSTMTP00000029213	64.7312	50.7527
ENSG00000179455	homo_sapiens	ENSP00000313881	11.8343	8.6785	hucho_hucho	ENSHHUP00000000957	81.0811	59.4595
ENSG00000179455	homo_sapiens	ENSP00000313881	6.50888	5.52268	hucho_hucho	ENSHHUP00000005272	48.5294	41.1765
ENSG00000179455	homo_sapiens	ENSP00000313881	51.8738	37.8698	betta_splendens	ENSBSLP00000015756	61.1628	44.6512
ENSG00000179455	homo_sapiens	ENSP00000313881	51.4793	39.0533	pygocentrus_nattereri	ENSPNAP00000002281	58.1292	44.098
ENSG00000179455	homo_sapiens	ENSP00000313881	51.6765	39.2505	anabas_testudineus	ENSATEP00000033645	60.7889	46.1717
ENSG00000179455	homo_sapiens	ENSP00000313881	16.9625	9.07298	saccharomyces_cerevisiae	YPL054W	28.5714	15.2824
ENSG00000179455	homo_sapiens	ENSP00000313881	51.2821	38.0671	seriola_lalandi_dorsalis	ENSSLDP00000018304	60.3248	44.7796
ENSG00000179455	homo_sapiens	ENSP00000313881	51.4793	38.0671	labrus_bergylta	ENSLBEP00000032267	60.5568	44.7796
ENSG00000179455	homo_sapiens	ENSP00000313881	52.071	38.6588	pundamilia_nyererei	ENSPNYP00000019784	61.2529	45.4756
ENSG00000179455	homo_sapiens	ENSP00000313881	51.6765	38.2643	mastacembelus_armatus	ENSMAMP00000034640	60.7889	45.0116
ENSG00000179455	homo_sapiens	ENSP00000313881	51.6765	38.4615	stegastes_partitus	ENSSPAP00000011952	60.7889	45.2436
ENSG00000179455	homo_sapiens	ENSP00000313881	52.071	38.4615	acanthochromis_polyacanthus	ENSAPOP00000020759	61.2529	45.2436
ENSG00000179455	homo_sapiens	ENSP00000313881	58.5799	46.1538	aquila_chrysaetos_chrysaetos	ENSACCP00020010810	62.2642	49.0566
ENSG00000179455	homo_sapiens	ENSP00000313881	52.2682	39.4477	nothobranchius_furzeri	ENSNFUP00015005621	61.4849	46.4037
ENSG00000179455	homo_sapiens	ENSP00000313881	51.6765	38.0671	cyprinodon_variegatus	ENSCVAP00000005840	60.7889	44.7796
ENSG00000179455	homo_sapiens	ENSP00000313881	52.071	38.856	denticeps_clupeoides	ENSDCDP00000053879	59.8639	44.6712
ENSG00000179455	homo_sapiens	ENSP00000313881	51.6765	38.2643	larimichthys_crocea	ENSLCRP00005050087	61.215	45.3271
ENSG00000179455	homo_sapiens	ENSP00000313881	50.6903	37.4753	takifugu_rubripes	ENSTRUP00000030503	55.8696	41.3043
ENSG00000179455	homo_sapiens	ENSP00000313881	56.0158	43.3925	ficedula_albicollis	ENSFALP00000003876	60.6838	47.0085
ENSG00000179455	homo_sapiens	ENSP00000313881	48.1262	36.2919	hippocampus_comes	ENSHCOP00000007200	58.5132	44.1247
ENSG00000179455	homo_sapiens	ENSP00000313881	51.4793	38.856	cyprinus_carpio_carpio	ENSCCRP00000029845	58.6517	44.2697
ENSG00000179455	homo_sapiens	ENSP00000313881	51.6765	39.0533	cyprinus_carpio_carpio	ENSCCRP00000029828	55.6263	42.0382
ENSG00000179455	homo_sapiens	ENSP00000313881	57.5937	44.9704	coturnix_japonica	ENSCJPP00005025949	62.6609	48.927
ENSG00000179455	homo_sapiens	ENSP00000313881	52.2682	38.4615	poecilia_latipinna	ENSPLAP00000026269	60.6407	44.6224
ENSG00000179455	homo_sapiens	ENSP00000313881	45.1677	33.925	sinocyclocheilus_grahami	ENSSGRP00000074106	58.8689	44.2159
ENSG00000179455	homo_sapiens	ENSP00000313881	51.8738	38.4615	sinocyclocheilus_grahami	ENSSGRP00000000225	59.7727	44.3182
ENSG00000179455	homo_sapiens	ENSP00000313881	52.071	38.6588	maylandia_zebra	ENSMZEP00005025614	61.2529	45.4756
ENSG00000179455	homo_sapiens	ENSP00000313881	49.7041	36.8836	tetraodon_nigroviridis	ENSTNIP00000003623	58.8785	43.6916
ENSG00000179455	homo_sapiens	ENSP00000313881	52.86	40.2367	paramormyrops_kingsleyae	ENSPKIP00000012692	57.3876	43.6831
ENSG00000179455	homo_sapiens	ENSP00000313881	51.4793	40.0394	scleropages_formosus	ENSSFOP00015026635	58.5202	45.5157
ENSG00000179455	homo_sapiens	ENSP00000313881	41.4201	31.7554	leptobrachium_leishanense	ENSLLEP00000025565	58.6592	44.9721
ENSG00000179455	homo_sapiens	ENSP00000313881	49.1124	36.6864	scophthalmus_maximus	ENSSMAP00000018331	55.0885	41.1504
ENSG00000179455	homo_sapiens	ENSP00000313881	51.4793	38.6588	oryzias_melastigma	ENSOMEP00000033373	60.5568	45.4756

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000209	involved_in protein polyubiquitination	1	ISS	Homo_sapiens(9606)	Process
GO:0003723	enables RNA binding	1	ISS	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0016567	involved_in protein ubiquitination	1	IBA	Homo_sapiens(9606)	Process
GO:0042802	enables identical protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0046872	enables metal ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0061630	enables ubiquitin protein ligase activity	2	IBA,ISS	Homo_sapiens(9606)	Function
GO:1990904	part_of ribonucleoprotein complex	1	ISS	Homo_sapiens(9606)	Component