RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	Stress granucle
BulkPerturb-seq

Ensembl ID	ENSG00000179046	Gene ID	205860	Accession	26378
Symbol	TRIML2	Alias	SPRYD6	Full Name	tripartite motif family like 2
Status	Confidence	Length	18332 bases	Strand	Minus strand
Position	4 : 188091272 - 188109603	RNA binding domain	SPRY
Summary	This gene encodes a member of the tri-partite motif (TRIM) family of proteins. This protein may be regulated by the tumor suppressor p53 and may regulate p53 through the enhancement of p53 SUMOylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000317498	SPRY	PF00622	7.6e-12	1
ENSP00000422581	SPRY	PF00622	7.9e-12	1
ENSP00000507413	SPRY	PF00622	7.9e-12	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
TRIML2-207	ENST00000512729	1639	437aa	ENSP00000422581
TRIML2-201	ENST00000326754	1305	422aa	ENSP00000317498
TRIML2-205	ENST00000503475	1006	118aa	ENSP00000421575
TRIML2-204	ENST00000503141	1242	118aa	ENSP00000426074
TRIML2-206	ENST00000511771	1252	No protein	-
TRIML2-203	ENST00000502707	541	No protein	-
TRIML2-202	ENST00000394461	536	No protein	-
TRIML2-208	ENST00000682553	1998	437aa	ENSP00000507413

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
91989	3-hydroxy-1-methylpropylmercapturic acid	1E-6	26053186
91990	Smoking	1E-6	26053186

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005737	is_active_in cytoplasm	1	IBA	Homo_sapiens(9606)	Component
GO:0008270	enables zinc ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0010468	involved_in regulation of gene expression	1	IBA	Homo_sapiens(9606)	Process
GO:0016567	involved_in protein ubiquitination	2	IBA,IEA	Homo_sapiens(9606)	Process
GO:0032526	involved_in response to retinoic acid	1	IEA	Homo_sapiens(9606)	Process
GO:0042802	enables identical protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0045087	involved_in innate immune response	1	IBA	Homo_sapiens(9606)	Process
GO:0061630	enables ubiquitin protein ligase activity	1	IBA	Homo_sapiens(9606)	Function