Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions TF
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000177599 Gene ID 126069 Accession 23706
Symbol ZNF491 Alias NA Full Name zinc finger protein 491
Status Confidence Length 9981 bases Strand Plus strand
Position 19 : 11798523 - 11808503 RNA binding domain zf-met
Summary Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000313443 zf-met PF12874 0.00051 1
ENSP00000313443 zf-met PF12874 0.00051 2

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
ZNF491-203 ENST00000479762 436 No protein -
ZNF491-201 ENST00000323169 2888 437aa ENSP00000313443
ZNF491-202 ENST00000450087 578 139aa ENSP00000392176
ZNF491-204 ENST00000492230 512 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000177599homo_sapiensENSP0000040298560.070748.0565homo_sapiensENSP0000031344377.803262.2426
ENSG00000177599homo_sapiensENSP0000040201760.152348.9848homo_sapiensENSP0000031344354.233444.1648
ENSG00000177599homo_sapiensENSP0000050693061.706352.5794homo_sapiensENSP0000031344371.16760.6407
ENSG00000177599homo_sapiensENSP0000030537353.949644.7059homo_sapiensENSP0000031344373.455460.8696
ENSG00000177599homo_sapiensENSP0000030260334.429827.193homo_sapiensENSP0000031344335.926828.3753
ENSG00000177599homo_sapiensENSP0000030148024.430418.9873homo_sapiensENSP0000031344344.164834.3249
ENSG00000177599homo_sapiensENSP0000033931437.892428.0269homo_sapiensENSP0000031344338.672828.6041
ENSG00000177599homo_sapiensENSP0000036730024.202114.7606homo_sapiensENSP0000031344341.647625.4005
ENSG00000177599homo_sapiensENSP0000025297926.364816.7776homo_sapiensENSP0000031344345.308928.833
ENSG00000177599homo_sapiensENSP0000047000826.617418.4843homo_sapiensENSP0000031344332.951922.8833
ENSG00000177599homo_sapiensENSP000003829572012.3333homo_sapiensENSP0000031344313.738.46682
ENSG00000177599homo_sapiensENSP0000037981620.666712.6667homo_sapiensENSP0000031344314.18768.69565
ENSG00000177599homo_sapiensENSP0000038302020.666712.3333homo_sapiensENSP0000031344314.18768.46682
ENSG00000177599homo_sapiensENSP000003829872012.3333homo_sapiensENSP0000031344313.738.46682
ENSG00000177599homo_sapiensENSP0000027064927.692319.4872homo_sapiensENSP0000031344337.070926.087
ENSG00000177599homo_sapiensENSP0000045441825.786218.7107homo_sapiensENSP0000031344337.528627.2311
ENSG00000177599homo_sapiensENSP0000038161336.706328.5714homo_sapiensENSP0000031344342.334132.9519
ENSG00000177599homo_sapiensENSP0000038099933.020625.8912homo_sapiensENSP0000031344340.274631.5789
ENSG00000177599homo_sapiensENSP0000032113225.092918.0297homo_sapiensENSP0000031344330.892422.1968
ENSG00000177599homo_sapiensENSP0000040437040.211630.9524homo_sapiensENSP0000031344334.782626.7735
ENSG00000177599homo_sapiensENSP0000036179123.954418.0608homo_sapiensENSP0000031344328.83321.7391
ENSG00000177599homo_sapiensENSP0000033485338.375830.8917homo_sapiensENSP0000031344355.148744.3936
ENSG00000177599homo_sapiensENSP0000034672923.076915.3846homo_sapiensENSP0000031344319.22212.8146
ENSG00000177599homo_sapiensENSP0000037879228.358218.7396homo_sapiensENSP0000031344339.130425.8581
ENSG00000177599homo_sapiensENSP0000044036536.752128.7749homo_sapiensENSP0000031344329.519523.1121
ENSG00000177599homo_sapiensENSP0000032226535.308124.1706homo_sapiensENSP0000031344334.096123.341
ENSG00000177599homo_sapiensENSP0000037920824.006916.4076homo_sapiensENSP0000031344331.807821.7391
ENSG00000177599homo_sapiensENSP0000035454724.531818.1648homo_sapiensENSP0000031344329.977122.1968
ENSG00000177599homo_sapiensENSP0000043759024.080917.8309homo_sapiensENSP0000031344329.977122.1968
ENSG00000177599homo_sapiensENSP0000033543754.323344.5489homo_sapiensENSP0000031344366.132754.2334
ENSG00000177599homo_sapiensENSP0000024821128.795820.7679homo_sapiensENSP0000031344337.757427.2311
ENSG00000177599homo_sapiensENSP0000037599431.718821.25homo_sapiensENSP0000031344346.453131.1213
ENSG00000177599homo_sapiensENSP0000040528924.306518.4941homo_sapiensENSP0000031344342.105332.0366
ENSG00000177599homo_sapiensENSP0000039233517.39139.66184homo_sapiensENSP000003134438.237994.57666
ENSG00000177599homo_sapiensENSP0000041152626.55521.2919homo_sapiensENSP0000031344325.400520.3661
ENSG00000177599homo_sapiensENSP0000028817732.969423.7991homo_sapiensENSP0000031344334.553824.9428
ENSG00000177599homo_sapiensENSP0000046557830.905924.3339homo_sapiensENSP0000031344339.816931.3501
ENSG00000177599homo_sapiensENSP0000030222237.280728.0702homo_sapiensENSP0000031344338.901629.2906
ENSG00000177599homo_sapiensENSP0000047476033.457224.7212homo_sapiensENSP0000031344341.189930.4348
ENSG00000177599homo_sapiensENSP0000046561928.820122.6306homo_sapiensENSP0000031344334.096126.7735
ENSG00000177599homo_sapiensENSP0000041299928.229722.1691homo_sapiensENSP0000031344340.503431.8078
ENSG00000177599homo_sapiensENSP0000033380233.163325.8503homo_sapiensENSP0000031344344.622434.7826
ENSG00000177599homo_sapiensENSP0000026309528.070221.3716homo_sapiensENSP0000031344340.274630.6636
ENSG00000177599homo_sapiensENSP0000046605133.876824.8188homo_sapiensENSP0000031344342.791831.3501
ENSG00000177599homo_sapiensENSP0000041719236.6327.1062homo_sapiensENSP0000031344322.883316.9336
ENSG00000177599homo_sapiensENSP0000029668220.357915.1007homo_sapiensENSP0000031344341.647630.8924
ENSG00000177599homo_sapiensENSP0000046802129.624121.6541homo_sapiensENSP0000031344345.080132.9519
ENSG00000177599homo_sapiensENSP0000050708333.26425.3638homo_sapiensENSP0000031344336.613327.9176
ENSG00000177599homo_sapiensENSP0000047127724.875620.6468homo_sapiensENSP0000031344322.883318.9931
ENSG00000177599homo_sapiensENSP0000025284023.023318.3721homo_sapiensENSP0000031344322.654518.0778
ENSG00000177599homo_sapiensENSP0000036334430.634923.4921homo_sapiensENSP0000031344344.164833.8673
ENSG00000177599homo_sapiensENSP0000040663829.969421.4067homo_sapiensENSP0000031344344.851332.0366
ENSG00000177599homo_sapiensENSP0000036178430.423321.4286homo_sapiensENSP0000031344326.315818.5355
ENSG00000177599homo_sapiensENSP0000051430627.725120.6161homo_sapiensENSP0000031344326.773519.9085
ENSG00000177599homo_sapiensENSP0000050676924.826417.5347homo_sapiensENSP0000031344332.723123.1121
ENSG00000177599homo_sapiensENSP000003457979.941525.26316homo_sapiensENSP000003134433.890162.0595
ENSG00000177599homo_sapiensENSP0000031905338.165129.7248homo_sapiensENSP0000031344347.597337.0709
ENSG00000177599homo_sapiensENSP0000037936832.447823.3397homo_sapiensENSP0000031344339.130428.1465
ENSG00000177599homo_sapiensENSP0000046671431.331224.1883homo_sapiensENSP0000031344344.164834.0961
ENSG00000177599homo_sapiensENSP0000038871028.472218.9236homo_sapiensENSP0000031344337.528624.9428
ENSG00000177599homo_sapiensENSP0000033398024.293115.6812homo_sapiensENSP0000031344343.249427.9176
ENSG00000177599homo_sapiensENSP0000027877229.549221.0351homo_sapiensENSP0000031344340.503428.833

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000177599homo_sapiensENSP0000031344396.567595.4233gorilla_gorillaENSGGOP0000002437896.567595.4233
ENSG00000177599homo_sapiensENSP0000031344324.485116.476erinaceus_europaeusENSEEUP0000000787928.533319.2
ENSG00000177599homo_sapiensENSP000003134438.695654.34783mus_spretusMGP_SPRETEiJ_P00806297.450983.72549
ENSG00000177599homo_sapiensENSP0000031344334.782626.5446jaculus_jaculusENSJJAP0000000459530.158723.0159
ENSG00000177599homo_sapiensENSP0000031344346.453137.9863ovis_aries_rambouilletENSOARP0002000038256.232745.9834
ENSG00000177599homo_sapiensENSP0000031344329.061822.6545ochotona_princepsENSOPRP0000001134327.912121.7582
ENSG00000177599homo_sapiensENSP0000031344335.469126.7735mus_caroliMGP_CAROLIEiJ_P007735324.818.72
ENSG00000177599homo_sapiensENSP0000031344335.469126.087mus_musculusENSMUSP0000014715430.273422.2656
ENSG00000177599homo_sapiensENSP0000031344336.384428.1465dipodomys_ordiiENSDORP0000002249631.927724.6988
ENSG00000177599homo_sapiensENSP0000031344318.306612.8146vicugna_pacosENSVPAP0000001018724.767817.3375
ENSG00000177599homo_sapiensENSP0000031344334.324927.0023mesocricetus_auratusENSMAUP0000001389129.354223.092
ENSG00000177599homo_sapiensENSP0000031344334.782627.0023microtus_ochrogasterENSMOCP0000002451029.745623.092
ENSG00000177599homo_sapiensENSP0000031344334.782626.5446peromyscus_maniculatus_bairdiiENSPEMP0000000554426.760620.4225
ENSG00000177599homo_sapiensENSP0000031344335.469126.087mus_spicilegusENSMSIP0000000054530.273422.2656
ENSG00000177599homo_sapiensENSP0000031344334.782627.2311nannospalax_galiliENSNGAP0000001196529.803923.3333
ENSG00000177599homo_sapiensENSP0000031344332.494324.714mus_pahariMGP_PahariEiJ_P004571725.912419.708
ENSG00000177599homo_sapiensENSP0000031344325.858116.476drosophila_melanogasterFBpp007046622.554914.3713
ENSG00000177599homo_sapiensENSP0000031344324.942816.9336drosophila_melanogasterFBpp008198520.260213.7546
ENSG00000177599homo_sapiensENSP0000031344331.121318.3066drosophila_melanogasterFBpp007532314.00628.23893
ENSG00000177599homo_sapiensENSP0000031344322.654515.103clupea_harengusENSCHAP0000001961417.010311.3402
ENSG00000177599homo_sapiensENSP0000031344333.638420.3661oncorhynchus_kisutchENSOKIP0000502954118.238211.0422
ENSG00000177599homo_sapiensENSP0000031344333.180820.3661salmo_salarENSSSAP0000015665018.23911.195
ENSG00000177599homo_sapiensENSP0000031344333.180820.1373salmo_truttaENSSTUP0000006976518.23911.0692
ENSG00000177599homo_sapiensENSP0000031344333.409620.3661salmo_truttaENSSTUP0000006398418.295711.1529
ENSG00000177599homo_sapiensENSP0000031344329.748318.5355fundulus_heteroclitusENSFHEP0000001150514.55779.07055
ENSG00000177599homo_sapiensENSP0000031344328.83318.9931fundulus_heteroclitusENSFHEP0000002061428.83318.9931
ENSG00000177599homo_sapiensENSP0000031344329.748317.849poecilia_reticulataENSPREP0000002204823.76614.2596
ENSG00000177599homo_sapiensENSP0000031344330.434818.7643xiphophorus_maculatusENSXMAP0000002079015.90919.80861
ENSG00000177599homo_sapiensENSP0000031344320.823815.7895xiphophorus_maculatusENSXMAP0000004131924.266718.4
ENSG00000177599homo_sapiensENSP0000031344320.823815.7895xiphophorus_maculatusENSXMAP0000002519724.266718.4
ENSG00000177599homo_sapiensENSP0000031344318.306613.73xiphophorus_maculatusENSXMAP0000003443534.482825.8621
ENSG00000177599homo_sapiensENSP0000031344331.121319.4508haplochromis_burtoniENSHBUP0000002207718.604711.6279
ENSG00000177599homo_sapiensENSP0000031344331.578919.6796astatotilapia_callipteraENSACLP0000001055918.878211.7647
ENSG00000177599homo_sapiensENSP0000031344331.350119.4508astatotilapia_callipteraENSACLP0000002906718.792911.6598
ENSG00000177599homo_sapiensENSP0000031344314.874111.8993sparus_aurataENSSAUP0001005260922.887318.3099
ENSG00000177599homo_sapiensENSP0000031344330.205921.2815lates_calcariferENSLCAP0001002904024.043716.9399
ENSG00000177599homo_sapiensENSP0000031344317.84912.8146neolamprologus_brichardiENSNBRP0000001757430.708722.0472
ENSG00000177599homo_sapiensENSP0000031344331.350119.6796neolamprologus_brichardiENSNBRP0000003200118.741411.7647
ENSG00000177599homo_sapiensENSP0000031344322.425617.3913kryptolebias_marmoratusENSKMAP0000001846823.38918.1384
ENSG00000177599homo_sapiensENSP0000031344331.807820.3661kryptolebias_marmoratusENSKMAP0000001776718.075411.5735
ENSG00000177599homo_sapiensENSP0000031344311.67057.55149oryzias_javanicusENSOJAP0000001663321.51913.9241
ENSG00000177599homo_sapiensENSP0000031344327.231118.3066dicentrarchus_labraxENSDLAP0000506925425.646617.2414
ENSG00000177599homo_sapiensENSP0000031344321.96817.6201amphiprion_perculaENSAPEP0000002649931.270425.0814
ENSG00000177599homo_sapiensENSP0000031344313.272310.7551oryzias_sinensisENSOSIP0000003321423.481819.0283
ENSG00000177599homo_sapiensENSP0000031344329.977119.4508seriola_dumeriliENSSDUP0000002871817.945211.6438
ENSG00000177599homo_sapiensENSP0000031344318.077814.1876seriola_dumeriliENSSDUP0000000164435.111127.5556
ENSG00000177599homo_sapiensENSP0000031344331.121320.3661seriola_dumeriliENSSDUP0000000056614.81489.69499
ENSG00000177599homo_sapiensENSP0000031344325.858121.5103cottoperca_gobioENSCGOP0000001670423.108419.2229
ENSG00000177599homo_sapiensENSP0000031344331.578924.9428cottoperca_gobioENSCGOP0000000064128.163322.2449
ENSG00000177599homo_sapiensENSP0000031344324.485120.1373cottoperca_gobioENSCGOP0000005128522.912218.8437
ENSG00000177599homo_sapiensENSP0000031344328.604122.8833cottoperca_gobioENSCGOP0000005140532.051325.641
ENSG00000177599homo_sapiensENSP0000031344321.510316.7048cottoperca_gobioENSCGOP0000000959224.479219.0104
ENSG00000177599homo_sapiensENSP0000031344329.748319.9085myripristis_murdjanENSMMDP0000500314534.946223.3871
ENSG00000177599homo_sapiensENSP0000031344313.738.46682myripristis_murdjanENSMMDP0000500876933.707920.7865
ENSG00000177599homo_sapiensENSP0000031344317.84914.8741sander_luciopercaENSSLUP0000003140925.242721.0356
ENSG00000177599homo_sapiensENSP0000031344328.375319.4508sander_luciopercaENSSLUP0000004798827.555618.8889
ENSG00000177599homo_sapiensENSP0000031344329.290626.087sander_luciopercaENSSLUP0000003661233.246829.6104
ENSG00000177599homo_sapiensENSP0000031344319.450814.6453amphiprion_ocellarisENSAOCP0000002336326.153819.6923
ENSG00000177599homo_sapiensENSP0000031344314.874111.4416terrapene_carolina_triunguisENSTMTP0000001881123.214317.8571
ENSG00000177599homo_sapiensENSP0000031344329.519519.6796hucho_huchoENSHHUP0000003079626.272917.5153
ENSG00000177599homo_sapiensENSP0000031344330.434819.6796betta_splendensENSBSLP0000004621825.430216.4436
ENSG00000177599homo_sapiensENSP0000031344329.290618.9931pygocentrus_nattereriENSPNAP0000003795515.18399.84579
ENSG00000177599homo_sapiensENSP0000031344317.162512.357anabas_testudineusENSATEP0000003572025.510218.3673
ENSG00000177599homo_sapiensENSP0000031344330.205919.222seriola_lalandi_dorsalisENSSLDP0000000942218.057511.4911
ENSG00000177599homo_sapiensENSP0000031344328.375321.2815seriola_lalandi_dorsalisENSSLDP0000003074329.383922.0379
ENSG00000177599homo_sapiensENSP0000031344320.823816.7048pundamilia_nyerereiENSPNYP0000001019328.086422.5309
ENSG00000177599homo_sapiensENSP0000031344331.350119.4508pundamilia_nyerereiENSPNYP0000000695918.741411.6279
ENSG00000177599homo_sapiensENSP0000031344314.645310.0687mastacembelus_armatusENSMAMP0000006655023.188415.942
ENSG00000177599homo_sapiensENSP0000031344333.638420.3661oncorhynchus_tshawytschaENSOTSP0000502189618.352111.1111
ENSG00000177599homo_sapiensENSP000003134439.382158.23799acanthochromis_polyacanthusENSAPOP0000000417139.805834.9515
ENSG00000177599homo_sapiensENSP0000031344331.121320.3661nothobranchius_furzeriENSNFUP0001500928222.006514.4013
ENSG00000177599homo_sapiensENSP0000031344329.290617.849cyprinodon_variegatusENSCVAP0000000614715.59079.50061
ENSG00000177599homo_sapiensENSP0000031344331.121319.9085cyprinodon_variegatusENSCVAP0000003015823.529415.0519
ENSG00000177599homo_sapiensENSP0000031344319.908515.3318takifugu_rubripesENSTRUP0000004932924.099718.5596
ENSG00000177599homo_sapiensENSP0000031344334.553827.0023takifugu_rubripesENSTRUP0000005245522.948317.9331
ENSG00000177599homo_sapiensENSP0000031344317.391314.8741takifugu_rubripesENSTRUP0000005325831.147526.6393
ENSG00000177599homo_sapiensENSP0000031344330.892423.1121takifugu_rubripesENSTRUP0000004450931.395323.4884
ENSG00000177599homo_sapiensENSP0000031344317.162513.0435takifugu_rubripesENSTRUP0000003108527.173920.6522
ENSG00000177599homo_sapiensENSP0000031344331.807819.4508hippocampus_comesENSHCOP0000001120218.809211.502
ENSG00000177599homo_sapiensENSP0000031344327.917617.3913poecilia_latipinnaENSPLAP0000002728213.04818.12834
ENSG00000177599homo_sapiensENSP0000031344331.350119.9085maylandia_zebraENSMZEP0000503743630.925519.6388
ENSG00000177599homo_sapiensENSP0000031344323.34118.7643maylandia_zebraENSMZEP0000502256132.38126.0317
ENSG00000177599homo_sapiensENSP0000031344324.71419.222tetraodon_nigroviridisENSTNIP0000000857934.177226.5823
ENSG00000177599homo_sapiensENSP0000031344322.425615.3318scophthalmus_maximusENSSMAP0000004652026.558318.1572
ENSG00000177599homo_sapiensENSP0000031344328.604118.5355oryzias_melastigmaENSOMEP0000001959922.727314.7273
ENSG00000177599homo_sapiensENSP0000031344331.350120.3661oryzias_melastigmaENSOMEP0000003468516.21310.5325

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000122involved_in negative regulation of transcription by RNA polymerase II1IBAHomo_sapiens(9606)Process
GO:0000977enables RNA polymerase II transcription regulatory region sequence-specific DNA binding1IBAHomo_sapiens(9606)Function
GO:0001227enables DNA-binding transcription repressor activity, RNA polymerase II-specific1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IEAHomo_sapiens(9606)Component
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function

Expression