RBP Type
Canonical_RBPs
Diseases
N.A.
Drug
N.A.
Main interacting RNAs
N.A.
Moonlighting functions
TF
Localizations
N.A.
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000176083 Gene ID
257101 Accession
28495
Symbol
ZNF683
Alias
Hobit
Full Name
zinc finger protein 683
Status
Confidence
Length
12889 bases
Strand
Minus strand
Position
1 : 26361634 - 26374522
RNA binding domain
zf-met
Summary
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in T cell receptor signaling pathway; cellular response to ionomycin; and regulation of gene expression. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000344095
zf-met
PF12874 1.6e-05
1
ENSP00000384782
zf-met
PF12874 3.7e-05
1
ENSP00000388792
zf-met
PF12874 3.7e-05
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
Name
Transcript ID
bp
Protein
Translation ID
ZNF683-202
ENST00000403843
1670
524aa
ENSP00000384782
ZNF683-201
ENST00000349618
1628
504aa
ENSP00000344095
ZNF683-205
ENST00000436292
1712
524aa
ENSP00000388792
ZNF683-209
ENST00000455900
1080
282aa
ENSP00000411289
ZNF683-206
ENST00000451801
936
269aa
ENSP00000411290
ZNF683-208
ENST00000454975
592
154aa
ENSP00000412881
ZNF683-207
ENST00000453132
662
122aa
ENSP00000406734
ZNF683-204
ENST00000423508
744
197aa
ENSP00000391584
ZNF683-203
ENST00000416125
853
188aa
ENSP00000401961
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
6456 Fibrinogen 5.06755259128007E-6 17903294 6473 Fibrinogen 3.1609284290016E-7 17903294 6508 Fibrinogen 2.80966344272029E-6 17903294 6848 C-Reactive Protein 6.27973106961988E-9 17903293 7295 Atrial Natriuretic Factor 5.82798663164273E-8 17903293 56384 Citalopram 7.2790000E-005 -
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000176083 homo_sapiens ENSP00000358217 14.2857 8.91089 homo_sapiens ENSP00000344095 20.0397 12.5 ENSG00000176083 homo_sapiens ENSP00000277554 11.7547 5.62181 homo_sapiens ENSP00000344095 13.6905 6.54762 ENSG00000176083 homo_sapiens ENSP00000411145 23.1579 13.8947 homo_sapiens ENSP00000344095 21.8254 13.0952 ENSG00000176083 homo_sapiens ENSP00000362763 18.1604 11.3208 homo_sapiens ENSP00000344095 15.2778 9.52381 ENSG00000176083 homo_sapiens ENSP00000270451 40.6091 27.4112 homo_sapiens ENSP00000344095 15.873 10.7143 ENSG00000176083 homo_sapiens ENSP00000361195 26.0606 16.9697 homo_sapiens ENSP00000344095 17.0635 11.1111 ENSG00000176083 homo_sapiens ENSP00000292431 14.0417 6.45161 homo_sapiens ENSP00000344095 14.6825 6.74603 ENSG00000176083 homo_sapiens ENSP00000267807 12.2574 6.33299 homo_sapiens ENSP00000344095 23.8095 12.3016 ENSG00000176083 homo_sapiens ENSP00000476746 16.092 7.35632 homo_sapiens ENSP00000344095 13.8889 6.34921 ENSG00000176083 homo_sapiens ENSP00000378286 13.7405 8.39695 homo_sapiens ENSP00000344095 14.2857 8.73016 ENSG00000176083 homo_sapiens ENSP00000294702 20.1422 13.7441 homo_sapiens ENSP00000344095 16.8651 11.5079 ENSG00000176083 homo_sapiens ENSP00000338807 18.9542 10.4575 homo_sapiens ENSP00000344095 28.7698 15.873 ENSG00000176083 homo_sapiens ENSP00000485750 17.4954 9.57643 homo_sapiens ENSP00000344095 18.8492 10.3175 ENSG00000176083 homo_sapiens ENSP00000302855 16.4207 9.5941 homo_sapiens ENSP00000344095 17.6587 10.3175 ENSG00000176083 homo_sapiens ENSP00000438647 22.449 13.9147 homo_sapiens ENSP00000344095 24.0079 14.881 ENSG00000176083 homo_sapiens ENSP00000364677 16.9935 10.8932 homo_sapiens ENSP00000344095 15.4762 9.92064 ENSG00000176083 homo_sapiens ENSP00000283268 23.7473 15.9041 homo_sapiens ENSP00000344095 21.627 14.4841 ENSG00000176083 homo_sapiens ENSP00000308759 7.03565 3.75235 homo_sapiens ENSP00000344095 14.881 7.93651 ENSG00000176083 homo_sapiens ENSP00000499212 15.1448 9.57684 homo_sapiens ENSP00000344095 13.4921 8.53175 ENSG00000176083 homo_sapiens ENSP00000293805 17.5365 11.691 homo_sapiens ENSP00000344095 16.6667 11.1111 ENSG00000176083 homo_sapiens ENSP00000301073 37.5 23.8636 homo_sapiens ENSP00000344095 19.6429 12.5 ENSG00000176083 homo_sapiens ENSP00000362760 18.3673 11.3379 homo_sapiens ENSP00000344095 16.0714 9.92064 ENSG00000176083 homo_sapiens ENSP00000450969 11.756 5.35714 homo_sapiens ENSP00000344095 15.6746 7.14286 ENSG00000176083 homo_sapiens ENSP00000253008 36.7847 21.5259 homo_sapiens ENSP00000344095 26.7857 15.6746 ENSG00000176083 homo_sapiens ENSP00000245663 13.9219 7.47029 homo_sapiens ENSP00000344095 16.2698 8.73016 ENSG00000176083 homo_sapiens ENSP00000384371 13.5977 8.49858 homo_sapiens ENSP00000344095 19.0476 11.9048 ENSG00000176083 homo_sapiens ENSP00000360017 12.6187 6.10583 homo_sapiens ENSP00000344095 18.4524 8.92857 ENSG00000176083 homo_sapiens ENSP00000320050 33.1395 23.2558 homo_sapiens ENSP00000344095 11.3095 7.93651
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000176083 homo_sapiens ENSP00000344095 92.2619 90.2778 nomascus_leucogenys ENSNLEP00000011211 90.4669 88.5214 ENSG00000176083 homo_sapiens ENSP00000344095 99.0079 99.0079 pan_paniscus ENSPPAP00000031605 95.229 95.229 ENSG00000176083 homo_sapiens ENSP00000344095 97.2222 95.8333 pongo_abelii ENSPPYP00000001947 93.5115 92.1756 ENSG00000176083 homo_sapiens ENSP00000344095 99.0079 99.0079 pan_troglodytes ENSPTRP00000000672 95.229 95.229 ENSG00000176083 homo_sapiens ENSP00000344095 99.0079 98.2143 gorilla_gorilla ENSGGOP00000007546 95.229 94.4657 ENSG00000176083 homo_sapiens ENSP00000344095 40.6746 30.9524 sarcophilus_harrisii ENSSHAP00000012850 51.1222 38.9027 ENSG00000176083 homo_sapiens ENSP00000344095 55.5556 50 dasypus_novemcinctus ENSDNOP00000023407 79.5455 71.5909 ENSG00000176083 homo_sapiens ENSP00000344095 51.7857 44.0476 erinaceus_europaeus ENSEEUP00000012320 50.8772 43.2749 ENSG00000176083 homo_sapiens ENSP00000344095 80.9524 76.1905 callithrix_jacchus ENSCJAP00000017951 84.6473 79.6681 ENSG00000176083 homo_sapiens ENSP00000344095 94.4444 92.2619 cercocebus_atys ENSCATP00000044596 90.8397 88.7405 ENSG00000176083 homo_sapiens ENSP00000344095 94.6429 91.6667 macaca_fascicularis ENSMFAP00000043078 87.8453 85.0829 ENSG00000176083 homo_sapiens ENSP00000344095 94.0476 92.2619 macaca_nemestrina ENSMNEP00000007640 90.458 88.7405 ENSG00000176083 homo_sapiens ENSP00000344095 95.0397 92.6587 papio_anubis ENSPANP00000034049 91.4122 89.1221 ENSG00000176083 homo_sapiens ENSP00000344095 94.0476 92.0635 mandrillus_leucophaeus ENSMLEP00000026547 90.458 88.5496 ENSG00000176083 homo_sapiens ENSP00000344095 69.246 61.7063 tursiops_truncatus ENSTTRP00000005359 67.1154 59.8077 ENSG00000176083 homo_sapiens ENSP00000344095 78.9683 71.4286 equus_asinus ENSEASP00005005282 78.9683 71.4286 ENSG00000176083 homo_sapiens ENSP00000344095 77.1825 68.8492 loxodonta_africana ENSLAFP00000001489 74.3786 66.348 ENSG00000176083 homo_sapiens ENSP00000344095 68.4524 60.3175 panthera_leo ENSPLOP00000014600 73.8758 65.0964 ENSG00000176083 homo_sapiens ENSP00000344095 71.627 64.2857 ailuropoda_melanoleuca ENSAMEP00000011115 72.49 65.0602 ENSG00000176083 homo_sapiens ENSP00000344095 64.0873 54.3651 oryctolagus_cuniculus ENSOCUP00000014585 70.6783 59.9562 ENSG00000176083 homo_sapiens ENSP00000344095 79.5635 72.0238 equus_caballus ENSECAP00000033733 73.309 66.362 ENSG00000176083 homo_sapiens ENSP00000344095 74.8016 66.0714 panthera_pardus ENSPPRP00000016734 70.4673 62.243 ENSG00000176083 homo_sapiens ENSP00000344095 58.7302 52.7778 marmota_marmota_marmota ENSMMMP00000015781 73.6318 66.1692 ENSG00000176083 homo_sapiens ENSP00000344095 79.5635 71.4286 balaenoptera_musculus ENSBMSP00010008865 79.5635 71.4286 ENSG00000176083 homo_sapiens ENSP00000344095 62.8968 55.1587 cavia_porcellus ENSCPOP00000023735 72.7064 63.7615 ENSG00000176083 homo_sapiens ENSP00000344095 75.5952 67.0635 felis_catus ENSFCAP00000011879 63.5 56.3333 ENSG00000176083 homo_sapiens ENSP00000344095 74.2064 67.0635 ursus_americanus ENSUAMP00000008210 74.3539 67.1968 ENSG00000176083 homo_sapiens ENSP00000344095 75.3968 67.8571 sus_scrofa ENSSSCP00000056160 76.6129 68.9516 ENSG00000176083 homo_sapiens ENSP00000344095 80.1587 73.4127 microcebus_murinus ENSMICP00000031448 78.2946 71.7054 ENSG00000176083 homo_sapiens ENSP00000344095 53.9683 47.0238 octodon_degus ENSODEP00000005665 71.0183 61.8799 ENSG00000176083 homo_sapiens ENSP00000344095 74.4048 67.0635 ursus_maritimus ENSUMAP00000017145 75.4527 68.008 ENSG00000176083 homo_sapiens ENSP00000344095 75.1984 67.0635 delphinapterus_leucas ENSDLEP00000012281 74.6063 66.5354 ENSG00000176083 homo_sapiens ENSP00000344095 79.1667 70.6349 physeter_catodon ENSPCTP00005007268 79.3241 70.7753 ENSG00000176083 homo_sapiens ENSP00000344095 58.3333 50.9921 dipodomys_ordii ENSDORP00000026588 72.9529 63.7717 ENSG00000176083 homo_sapiens ENSP00000344095 89.4841 85.119 aotus_nancymaae ENSANAP00000010059 78.2986 74.4792 ENSG00000176083 homo_sapiens ENSP00000344095 88.8889 83.9286 saimiri_boliviensis_boliviensis ENSSBOP00000030726 85.4962 80.7252 ENSG00000176083 homo_sapiens ENSP00000344095 50.1984 43.4524 vicugna_pacos ENSVPAP00000007511 60.2381 52.1429 ENSG00000176083 homo_sapiens ENSP00000344095 53.5714 52.1825 chlorocebus_sabaeus ENSCSAP00000017035 96.0854 93.5943 ENSG00000176083 homo_sapiens ENSP00000344095 61.5079 54.9603 tupaia_belangeri ENSTBEP00000009888 62.6263 55.9596 ENSG00000176083 homo_sapiens ENSP00000344095 78.373 70.8333 phocoena_sinus ENSPSNP00000003471 78.5288 70.9742 ENSG00000176083 homo_sapiens ENSP00000344095 78.9683 71.2302 camelus_dromedarius ENSCDRP00005008373 78.9683 71.2302 ENSG00000176083 homo_sapiens ENSP00000344095 76.5873 70.6349 carlito_syrichta ENSTSYP00000031557 75.6863 69.8039 ENSG00000176083 homo_sapiens ENSP00000344095 75.7936 67.0635 panthera_tigris_altaica ENSPTIP00000016161 72.4858 64.1366 ENSG00000176083 homo_sapiens ENSP00000344095 80.754 74.0079 prolemur_simus ENSPSMP00000016475 81.0757 74.3028 ENSG00000176083 homo_sapiens ENSP00000344095 66.6667 60.5159 pteropus_vampyrus ENSPVAP00000016288 64.9903 58.9942 ENSG00000176083 homo_sapiens ENSP00000344095 72.8175 66.4683 myotis_lucifugus ENSMLUP00000013903 72.3866 66.075 ENSG00000176083 homo_sapiens ENSP00000344095 73.8095 67.4603 rhinolophus_ferrumequinum ENSRFEP00010005511 73.0845 66.7976 ENSG00000176083 homo_sapiens ENSP00000344095 51.7857 46.4286 heterocephalus_glaber_female ENSHGLP00000036790 76.5396 68.6217 ENSG00000176083 homo_sapiens ENSP00000344095 93.6508 91.4683 rhinopithecus_bieti ENSRBIP00000022071 87.2458 85.2126 ENSG00000176083 homo_sapiens ENSP00000344095 73.8095 66.6667 sciurus_vulgaris ENSSVLP00005002999 71.6763 64.7399 ENSG00000176083 homo_sapiens ENSP00000344095 62.5 54.7619 procavia_capensis ENSPCAP00000009934 61.5234 53.9062 ENSG00000176083 homo_sapiens ENSP00000344095 68.8492 62.1032 chinchilla_lanigera ENSCLAP00000021361 73.3615 66.1734 ENSG00000176083 homo_sapiens ENSP00000344095 75.9921 68.6508 catagonus_wagneri ENSCWAP00000010052 77.5304 70.0405 ENSG00000176083 homo_sapiens ENSP00000344095 75.3968 68.254 otolemur_garnettii ENSOGAP00000002980 75.8483 68.6627 ENSG00000176083 homo_sapiens ENSP00000344095 89.2857 84.9206 cebus_imitator ENSCCAP00000002976 86.2069 81.9923 ENSG00000176083 homo_sapiens ENSP00000344095 64.4841 57.7381 urocitellus_parryii ENSUPAP00010027190 73.5294 65.8371 ENSG00000176083 homo_sapiens ENSP00000344095 93.8492 91.6667 rhinopithecus_roxellana ENSRROP00000000780 90.2672 88.1679 ENSG00000176083 homo_sapiens ENSP00000344095 77.7778 71.0317 propithecus_coquereli ENSPCOP00000017011 80.4928 73.5113
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000978 enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 1 IBA Homo_sapiens(9606) Function GO:0002250 involved_in adaptive immune response 1 IEA Homo_sapiens(9606) Process GO:0003700 enables DNA-binding transcription factor activity 1 IBA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005634 located_in nucleus 1 IEA Homo_sapiens(9606) Component GO:0006357 involved_in regulation of transcription by RNA polymerase II 1 IBA Homo_sapiens(9606) Process GO:0010468 involved_in regulation of gene expression 1 ISS Homo_sapiens(9606) Process GO:0032823 involved_in regulation of natural killer cell differentiation 1 ISS Homo_sapiens(9606) Process GO:0032826 involved_in regulation of natural killer cell differentiation involved in immune response 1 ISS Homo_sapiens(9606) Process GO:0033082 involved_in regulation of extrathymic T cell differentiation 1 ISS Homo_sapiens(9606) Process GO:0045087 involved_in innate immune response 1 IEA Homo_sapiens(9606) Process GO:0046872 enables metal ion binding 1 IEA Homo_sapiens(9606) Function GO:0051136 involved_in regulation of NK T cell differentiation 1 ISS Homo_sapiens(9606) Process GO:1990841 enables promoter-specific chromatin binding 1 ISS Homo_sapiens(9606) Function
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