Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-OC43FlavivirusesHIVSARS-COV-2SINVDengueZika
Drug N.A.
Main interacting RNAs ncRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000174780 Gene ID 6731 Accession 11303
Symbol SRP72 Alias BMFF;BMFS1;HEL103 Full Name signal recognition particle 72
Status Confidence Length 36065 bases Strand Plus strand
Position 4 : 56467617 - 56503681 RNA binding domain SRP72
Summary This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000424576 SRP72 PF08492 6.3e-22 1
ENSP00000495128 SRP72 PF08492 7.1e-22 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
21073748 Identification of amino acid residues in protein SRP72 required for binding to a kinked 5e motif of the human signal recognition particle RNA. Elena Iakhiaeva 2010-11-13 BMC molecular biology
15588816 Identification of an RNA-binding domain in human SRP72. Elena Iakhiaeva 2005-01-28 Journal of molecular biology
18441046 The 5e motif of eukaryotic signal recognition particle RNA contains a conserved adenosine for the binding of SRP72. Elena Iakhiaeva 2008-06-01 RNA (New York, N.Y.)
35008565 The Molecular Biodiversity of Protein Targeting and Protein Transport Related to the Endoplasmic Reticulum. Andrea Tirincsi 2021-12-23 International journal of molecular sciences
18347438 Identification of the RNA binding regions of SRP68/72 and SRP72 by systematic mutagenesis of human SRP RNA. Jiaming Yin 2007-11-01 RNA biology
18564060 Anti-cooperative assembly of the SRP19 and SRP68/72 components of the signal recognition particle. Subhra Tuhin Maity 2008-11-01 The Biochemical journal
20672053 Archaea signal recognition particle shows the way. Christian Zwieb 2010-06-28 Archaea (Vancouver, B.C.)
27899666 Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction. M M Matthias Becker 2017-01-09 Nucleic acids research
30649417 Reconstitution of the human SRP system and quantitative and systematic analysis of its ribosome interactions. Klemens Wild 2019-04-08 Nucleic acids research
28524878 Structure of the quaternary complex between SRP, SR, and translocon bound to the translating ribosome. Ahmad Jomaa 2017-05-19 Nature communications
25692231 RNA gymnastics in mammalian signal recognition particle assembly. Klemens Wild 2014-01-01 RNA biology
26275773 Noncanoncial signal recognition particle RNAs in a major eukaryotic phylum revealed by purification of SRP from the human pathogen Cryptococcus neoformans. A Phillip Dumesic 2015-10-15 Nucleic acids research
16672232 Protein SRP68 of human signal recognition particle: identification of the RNA and SRP72 binding domains. Elena Iakhiaeva 2006-06-01 Protein science : a publication of the Protein Society
16381838 The tmRDB and SRPDB resources. Sloth Ebbe Andersen 2006-01-01 Nucleic acids research

Transcripts

Name Transcript ID bp Protein Translation ID
SRP72-204 ENST00000510663 2406 610aa ENSP00000424576
SRP72-205 ENST00000642900 3855 671aa ENSP00000495128
SRP72-201 ENST00000504757 745 220aa ENSP00000473576
SRP72-202 ENST00000505314 1006 335aa ENSP00000425190
SRP72-207 ENST00000646537 1496 No protein -
SRP72-208 ENST00000646579 766 No protein -
SRP72-209 ENST00000647432 778 No protein -
SRP72-206 ENST00000646222 429 No protein -
SRP72-203 ENST00000507126 2235 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
59005Pulmonary Disease, Chronic Obstructive3.0600000E-00722837378
59011Pulmonary Disease, Chronic Obstructive5.0260000E-00722837378
99554Respiratory Function Tests5E-622837378

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000174780

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000174780homo_sapiensENSP0000049512893.144693.1446nomascus_leucogenysENSNLEP0000001074399.522399.5223
ENSG00000174780homo_sapiensENSP00000495128100100pan_paniscusENSPPAP00000039220100100
ENSG00000174780homo_sapiensENSP0000049512899.701999.7019pongo_abeliiENSPPYP0000001647599.701999.7019
ENSG00000174780homo_sapiensENSP0000049512877.794372.2802pan_troglodytesENSPTRP0000009003085.996779.9012
ENSG00000174780homo_sapiensENSP0000049512896.572395.8271pan_troglodytesENSPTRP0000007170796.428695.6845
ENSG00000174780homo_sapiensENSP0000049512896.274295.231gorilla_gorillaENSGGOP0000002877596.13195.0893
ENSG00000174780homo_sapiensENSP0000049512829.359227.2727ornithorhynchus_anatinusENSOANP0000003419289.954383.5616
ENSG00000174780homo_sapiensENSP0000049512828.017924.5902ornithorhynchus_anatinusENSOANP0000001363190.821379.7101
ENSG00000174780homo_sapiensENSP0000049512895.678191.0581sarcophilus_harrisiiENSSHAP0000003676989.04384.7434
ENSG00000174780homo_sapiensENSP0000049512883.606679.7317notamacropus_eugeniiENSMEUP0000000473683.856579.9701
ENSG00000174780homo_sapiensENSP0000049512882.414381.8182choloepus_hoffmanniENSCHOP0000001174282.537381.9403
ENSG00000174780homo_sapiensENSP0000049512894.634992.8465dasypus_novemcinctusENSDNOP0000003254878.395176.9136
ENSG00000174780homo_sapiensENSP0000049512880.327979.4337erinaceus_europaeusENSEEUP0000000236283.307682.3802
ENSG00000174780homo_sapiensENSP0000049512898.360796.8703echinops_telfairiENSETEP0000000422398.214396.7262
ENSG00000174780homo_sapiensENSP0000049512891.952390.7601callithrix_jacchusENSCJAP0000008043098.092296.8204
ENSG00000174780homo_sapiensENSP0000049512896.572395.38callithrix_jacchusENSCJAP0000003328397.737696.5309
ENSG00000174780homo_sapiensENSP0000049512899.552999.5529cercocebus_atysENSCATP0000000194199.552999.5529
ENSG00000174780homo_sapiensENSP0000049512899.403999.4039macaca_fascicularisENSMFAP0000001599999.403999.4039
ENSG00000174780homo_sapiensENSP0000049512899.403999.4039macaca_mulattaENSMMUP0000007750899.403999.4039
ENSG00000174780homo_sapiensENSP0000049512868.554465.8718macaca_nemestrinaENSMNEP0000003087190.019686.4971
ENSG00000174780homo_sapiensENSP0000049512895.976295.231macaca_nemestrinaENSMNEP0000002933795.833395.0893
ENSG00000174780homo_sapiensENSP0000049512899.552999.5529papio_anubisENSPANP0000000396899.552999.5529
ENSG00000174780homo_sapiensENSP0000049512831.594629.3592mandrillus_leucophaeusENSMLEP0000001625291.774985.2814
ENSG00000174780homo_sapiensENSP0000049512894.634993.8897mandrillus_leucophaeusENSMLEP0000001193795.921495.1662
ENSG00000174780homo_sapiensENSP0000049512892.548491.8033tursiops_truncatusENSTTRP0000001037797.949597.1609
ENSG00000174780homo_sapiensENSP0000049512899.105898.6587vulpes_vulpesENSVVUP0000000797799.105898.6587
ENSG00000174780homo_sapiensENSP0000049512898.211696.2742mus_spretusMGP_SPRETEiJ_P007142198.211696.2742
ENSG00000174780homo_sapiensENSP0000049512899.403998.8077equus_asinusENSEASP0000504835694.076293.512
ENSG00000174780homo_sapiensENSP0000049512897.615595.6781capra_hircusENSCHIP0000002418497.761295.8209
ENSG00000174780homo_sapiensENSP0000049512898.658797.7645loxodonta_africanaENSLAFP0000001533898.658797.7645
ENSG00000174780homo_sapiensENSP0000049512898.807798.2116panthera_leoENSPLOP0000000589298.807798.2116
ENSG00000174780homo_sapiensENSP0000049512898.658798.0626ailuropoda_melanoleucaENSAMEP0000003865697.496396.9072
ENSG00000174780homo_sapiensENSP0000049512898.807797.3174bos_indicus_hybridENSBIXP0000500227998.807797.3174
ENSG00000174780homo_sapiensENSP0000049512898.211697.6155oryctolagus_cuniculusENSOCUP0000001052798.211697.6155
ENSG00000174780homo_sapiensENSP0000049512898.956898.2116equus_caballusENSECAP0000005464398.956898.2116
ENSG00000174780homo_sapiensENSP0000049512899.254898.8077canis_lupus_familiarisENSCAFP0084501937299.254898.8077
ENSG00000174780homo_sapiensENSP0000049512898.807798.2116panthera_pardusENSPPRP0000002561998.807798.2116
ENSG00000174780homo_sapiensENSP0000049512899.254898.5097marmota_marmota_marmotaENSMMMP0000002427399.254898.5097
ENSG00000174780homo_sapiensENSP0000049512899.105898.5097balaenoptera_musculusENSBMSP0001000030599.105898.5097
ENSG00000174780homo_sapiensENSP0000049512897.168496.2742balaenoptera_musculusENSBMSP0001001124497.313496.4179
ENSG00000174780homo_sapiensENSP0000049512899.552998.3607cavia_porcellusENSCPOP0000002130899.552998.3607
ENSG00000174780homo_sapiensENSP0000049512898.807798.2116felis_catusENSFCAP0000002343398.660798.0655
ENSG00000174780homo_sapiensENSP0000049512830.700430.1043ursus_americanusENSUAMP0000003703194.063992.2374
ENSG00000174780homo_sapiensENSP0000049512861.102859.9106ursus_americanusENSUAMP0000000310295.127693.2715
ENSG00000174780homo_sapiensENSP0000049512889.269783.9046monodelphis_domesticaENSMODP0000002589195.8490.08
ENSG00000174780homo_sapiensENSP0000049512898.658797.1684bison_bison_bisonENSBBBP0000001209598.658797.1684
ENSG00000174780homo_sapiensENSP0000049512898.211697.6155monodon_monocerosENSMMNP0001501667498.211697.6155
ENSG00000174780homo_sapiensENSP0000049512895.976294.0387sus_scrofaENSSSCP0000000949298.021396.0426
ENSG00000174780homo_sapiensENSP0000049512894.038792.8465microcebus_murinusENSMICP0000003848395.173593.9668
ENSG00000174780homo_sapiensENSP0000049512896.423295.38octodon_degusENSODEP0000001658297.586796.5309
ENSG00000174780homo_sapiensENSP0000049512898.360797.0194jaculus_jaculusENSJJAP0000001649998.068496.7311
ENSG00000174780homo_sapiensENSP0000049512898.360797.0194ovis_aries_rambouilletENSOARP0002002501583.969582.8244
ENSG00000174780homo_sapiensENSP0000049512898.807798.0626ursus_maritimusENSUMAP0000001081998.807798.0626
ENSG00000174780homo_sapiensENSP0000049512897.019495.38ochotona_princepsENSOPRP0000001143597.019495.38
ENSG00000174780homo_sapiensENSP0000049512898.509797.9136delphinapterus_leucasENSDLEP0000001927498.509797.9136
ENSG00000174780homo_sapiensENSP0000049512898.807798.3607physeter_catodonENSPCTP0000500619098.807798.3607
ENSG00000174780homo_sapiensENSP0000049512898.211696.2742mus_caroliMGP_CAROLIEiJ_P006877098.211696.2742
ENSG00000174780homo_sapiensENSP0000049512898.211696.2742mus_musculusENSMUSP0000009864898.211696.2742
ENSG00000174780homo_sapiensENSP0000049512898.509797.0194dipodomys_ordiiENSDORP0000000015698.363196.875
ENSG00000174780homo_sapiensENSP0000049512898.360797.9136mustela_putorius_furoENSMPUP0000000478898.360797.9136
ENSG00000174780homo_sapiensENSP0000049512895.3893.5917aotus_nancymaaeENSANAP0000000582795.238193.4524
ENSG00000174780homo_sapiensENSP0000049512826.229525.0373saimiri_boliviensis_boliviensisENSSBOP0000003851986.274582.3529
ENSG00000174780homo_sapiensENSP0000049512824.739223.994saimiri_boliviensis_boliviensisENSSBOP0000003279692.737489.9441
ENSG00000174780homo_sapiensENSP0000049512830.253428.614saimiri_boliviensis_boliviensisENSSBOP0000003124491.855286.8778
ENSG00000174780homo_sapiensENSP0000049512897.317496.2742vicugna_pacosENSVPAP0000000042898.04896.997
ENSG00000174780homo_sapiensENSP0000049512895.23194.0387chlorocebus_sabaeusENSCSAP0000000138995.515794.3199
ENSG00000174780homo_sapiensENSP0000049512872.280270.4918tupaia_belangeriENSTBEP0000000641372.713670.9145
ENSG00000174780homo_sapiensENSP0000049512898.956897.9136mesocricetus_auratusENSMAUP0000000173698.809597.7679
ENSG00000174780homo_sapiensENSP0000049512889.418888.8227phocoena_sinusENSPSNP0000000160698.360797.7049
ENSG00000174780homo_sapiensENSP0000049512890.31389.7168camelus_dromedariusENSCDRP0000501291198.858198.2055
ENSG00000174780homo_sapiensENSP0000049512898.658798.0626camelus_dromedariusENSCDRP0000500948698.658798.0626
ENSG00000174780homo_sapiensENSP0000049512899.403998.9568carlito_syrichtaENSTSYP0000002306198.522998.0798
ENSG00000174780homo_sapiensENSP0000049512898.807798.2116panthera_tigris_altaicaENSPTIP0000002173998.807798.2116
ENSG00000174780homo_sapiensENSP0000049512898.658796.7213rattus_norvegicusENSRNOP0000008243894.30292.4501
ENSG00000174780homo_sapiensENSP0000049512899.105898.5097prolemur_simusENSPSMP0000002806899.105898.5097
ENSG00000174780homo_sapiensENSP0000049512898.658797.3174microtus_ochrogasterENSMOCP0000002366298.658797.3174
ENSG00000174780homo_sapiensENSP0000049512868.703467.6602sorex_araneusENSSARP0000000527368.703467.6602
ENSG00000174780homo_sapiensENSP0000049512898.360796.8703peromyscus_maniculatus_bairdiiENSPEMP0000001251697.922996.4392
ENSG00000174780homo_sapiensENSP0000049512898.807797.3174bos_mutusENSBMUP0000000906398.807797.3174
ENSG00000174780homo_sapiensENSP0000049512898.211696.1252mus_spicilegusENSMSIP0000002394598.211696.1252
ENSG00000174780homo_sapiensENSP0000049512898.956897.4665cricetulus_griseus_chok1gshdENSCGRP0000101207798.956897.4665
ENSG00000174780homo_sapiensENSP0000049512897.168496.5723pteropus_vampyrusENSPVAP0000000529098.192897.5904
ENSG00000174780homo_sapiensENSP0000049512898.956897.3174myotis_lucifugusENSMLUP0000000671898.370496.7407
ENSG00000174780homo_sapiensENSP0000049512895.976291.0581vombatus_ursinusENSVURP0001001444995.54990.6528
ENSG00000174780homo_sapiensENSP0000049512899.105898.3607rhinolophus_ferrumequinumENSRFEP0001000705199.402198.6547
ENSG00000174780homo_sapiensENSP0000049512898.509798.0626neovison_visonENSNVIP0000001910198.509798.0626
ENSG00000174780homo_sapiensENSP0000049512898.807797.4665bos_taurusENSBTAP0000001401598.807797.4665
ENSG00000174780homo_sapiensENSP0000049512896.721395.9762heterocephalus_glaber_femaleENSHGLP0000004471698.782398.0213
ENSG00000174780homo_sapiensENSP0000049512878.390575.2608rhinopithecus_bietiENSRBIP0000001165791.319487.6736
ENSG00000174780homo_sapiensENSP0000049512899.105898.6587canis_lupus_dingoENSCAFP0002003535697.364696.9253
ENSG00000174780homo_sapiensENSP0000049512899.254898.8077sciurus_vulgarisENSSVLP0000502463499.254898.8077
ENSG00000174780homo_sapiensENSP0000049512895.976291.2072phascolarctos_cinereusENSPCIP0000000089995.833391.0714
ENSG00000174780homo_sapiensENSP0000049512889.865988.9717procavia_capensisENSPCAP000000080489089.1045
ENSG00000174780homo_sapiensENSP0000049512898.211696.7213nannospalax_galiliENSNGAP0000001009498.211696.7213
ENSG00000174780homo_sapiensENSP0000049512898.807797.4665bos_grunniensENSBGRP0000003503798.807797.4665
ENSG00000174780homo_sapiensENSP0000049512898.658797.9136chinchilla_lanigeraENSCLAP0000000503098.658797.9136
ENSG00000174780homo_sapiensENSP0000049512898.062696.5723cervus_hanglu_yarkandensisENSCHYP0000002813598.062696.5723
ENSG00000174780homo_sapiensENSP0000049512897.317494.9329catagonus_wagneriENSCWAP0000001480496.884394.5104
ENSG00000174780homo_sapiensENSP0000049512899.105898.8077ictidomys_tridecemlineatusENSSTOP0000002793299.105898.8077
ENSG00000174780homo_sapiensENSP0000049512898.658797.4665otolemur_garnettiiENSOGAP0000000318898.658797.4665
ENSG00000174780homo_sapiensENSP0000049512895.08293.4426cebus_imitatorENSCCAP0000002597095.366293.722
ENSG00000174780homo_sapiensENSP0000049512894.038791.5052cebus_imitatorENSCCAP0000002608494.038791.5052
ENSG00000174780homo_sapiensENSP0000049512899.105898.8077urocitellus_parryiiENSUPAP0001002711499.105898.8077
ENSG00000174780homo_sapiensENSP0000049512896.423295.082moschus_moschiferusENSMMSP0000003292198.477997.1081
ENSG00000174780homo_sapiensENSP0000049512899.552999.5529rhinopithecus_roxellanaENSRROP0000002376999.552999.5529
ENSG00000174780homo_sapiensENSP0000049512898.211696.5723mus_pahariMGP_PahariEiJ_P003194997.919896.2853
ENSG00000174780homo_sapiensENSP0000049512882.712482.4143propithecus_coquereliENSPCOP0000001453599.284498.9267
ENSG00000174780homo_sapiensENSP0000049512850.074529.5082caenorhabditis_elegansF08D12.1.152.913431.1811
ENSG00000174780homo_sapiensENSP0000049512859.761640.0894drosophila_melanogasterFBpp008331961.692341.3846
ENSG00000174780homo_sapiensENSP0000049512863.040242.3249ciona_intestinalisENSCINP0000000493260.95140.9222
ENSG00000174780homo_sapiensENSP0000049512825.782419.6721petromyzon_marinusENSPMAP0000000978477.578559.1928
ENSG00000174780homo_sapiensENSP0000049512838.30130.5514petromyzon_marinusENSPMAP0000000777379.813763.6646
ENSG00000174780homo_sapiensENSP0000049512861.251946.9449eptatretus_burgeriENSEBUP0000000548280.746661.8861
ENSG00000174780homo_sapiensENSP0000049512883.010472.8763callorhinchus_miliiENSCMIP0000002637683.134372.9851
ENSG00000174780homo_sapiensENSP0000049512831.296627.4218latimeria_chalumnaeENSLACP0000000037587.866176.9874
ENSG00000174780homo_sapiensENSP0000049512888.971778.2414lepisosteus_oculatusENSLOCP0000000312485.899375.5396
ENSG00000174780homo_sapiensENSP0000049512888.375677.0492clupea_harengusENSCHAP0000002538488.772577.3952
ENSG00000174780homo_sapiensENSP0000049512877.794367.8092danio_rerioENSDARP0000001502687.731176.4706
ENSG00000174780homo_sapiensENSP0000049512887.779476.304carassius_auratusENSCARP0000013043388.305876.7616
ENSG00000174780homo_sapiensENSP0000049512887.183376.155carassius_auratusENSCARP0000002685681.5971.2692
ENSG00000174780homo_sapiensENSP0000049512888.822776.9001astyanax_mexicanusENSAMXP0000000409589.624177.594
ENSG00000174780homo_sapiensENSP0000049512887.779476.4531ictalurus_punctatusENSIPUP0000000025588.571477.1429
ENSG00000174780homo_sapiensENSP0000049512887.928576.006esox_luciusENSELUP0000002358187.407475.5556
ENSG00000174780homo_sapiensENSP0000049512886.736274.2176electrophorus_electricusENSEEEP0000000729787.256474.6627
ENSG00000174780homo_sapiensENSP0000049512887.779476.006oncorhynchus_kisutchENSOKIP0000506756982.262671.229
ENSG00000174780homo_sapiensENSP0000049512887.481475.4098oncorhynchus_kisutchENSOKIP0000507880587.221475.1857
ENSG00000174780homo_sapiensENSP0000049512887.630476.006oncorhynchus_mykissENSOMYP0000009826486.725775.2212
ENSG00000174780homo_sapiensENSP0000049512881.967270.9389oncorhynchus_mykissENSOMYP0000000693781.001570.1031
ENSG00000174780homo_sapiensENSP0000049512887.481475.7079salmo_salarENSSSAP0000000695085.072573.6232
ENSG00000174780homo_sapiensENSP0000049512887.779475.5589salmo_salarENSSSAP0000017871987.518675.3343
ENSG00000174780homo_sapiensENSP0000049512887.481475.5589salmo_truttaENSSTUP0000000111886.323574.5588
ENSG00000174780homo_sapiensENSP0000049512886.140174.3666salmo_truttaENSSTUP0000002543983.646972.2142
ENSG00000174780homo_sapiensENSP0000049512887.183374.3666gadus_morhuaENSGMOP0000006295087.837874.9249
ENSG00000174780homo_sapiensENSP0000049512889.269776.6021fundulus_heteroclitusENSFHEP0000003161682.734870.9945
ENSG00000174780homo_sapiensENSP0000049512889.269776.9001poecilia_reticulataENSPREP0000000915589.670777.2455
ENSG00000174780homo_sapiensENSP0000049512888.673676.4531xiphophorus_maculatusENSXMAP0000001838181.062769.891
ENSG00000174780homo_sapiensENSP0000049512888.077574.9627oryzias_latipesENSORLP0000003041988.605775.4123
ENSG00000174780homo_sapiensENSP0000049512888.077575.2608cyclopterus_lumpusENSCLMP0000502610386.656974.0469
ENSG00000174780homo_sapiensENSP0000049512877.794366.468cyclopterus_lumpusENSCLMP0000502623989.078576.1092
ENSG00000174780homo_sapiensENSP0000049512887.928576.155oreochromis_niloticusENSONIP0000000181986.257374.7076
ENSG00000174780homo_sapiensENSP0000049512889.418877.1982haplochromis_burtoniENSHBUP0000003364289.820477.5449
ENSG00000174780homo_sapiensENSP0000049512889.418877.0492astatotilapia_callipteraENSACLP0000002152489.820477.3952
ENSG00000174780homo_sapiensENSP0000049512889.269776.304sparus_aurataENSSAUP0001001802189.670776.6467
ENSG00000174780homo_sapiensENSP0000049512887.779476.006lates_calcariferENSLCAP0001000318490.199178.1011
ENSG00000174780homo_sapiensENSP0000049512890.61178.9866xenopus_tropicalisENSXETP0000002250590.207778.635
ENSG00000174780homo_sapiensENSP0000049512894.485886.1401chrysemys_picta_belliiENSCPBP0000002089894.485886.1401
ENSG00000174780homo_sapiensENSP0000049512893.740785.693sphenodon_punctatusENSSPUP0000001265293.601285.5655
ENSG00000174780homo_sapiensENSP0000049512830.700426.3785crocodylus_porosusENSCPRP0000500917484.426272.541
ENSG00000174780homo_sapiensENSP0000049512825.186320.2683crocodylus_porosusENSCPRP0000500916868.421155.0607
ENSG00000174780homo_sapiensENSP0000049512886.587278.8376laticauda_laticaudataENSLLTP0000000901990.923382.7856
ENSG00000174780homo_sapiensENSP0000049512892.399484.9478notechis_scutatusENSNSUP0000001023591.176583.8235
ENSG00000174780homo_sapiensENSP0000049512892.697585.0969pseudonaja_textilisENSPTXP0000001750491.470683.9706
ENSG00000174780homo_sapiensENSP0000049512895.08285.544anas_platyrhynchos_platyrhynchosENSAPLP0000000850194.518585.037
ENSG00000174780homo_sapiensENSP0000049512894.485886.7362gallus_gallusENSGALP0001000505794.485886.7362
ENSG00000174780homo_sapiensENSP0000049512891.952383.6066meleagris_gallopavoENSMGAP0000002336092.78284.3609
ENSG00000174780homo_sapiensENSP0000049512892.250483.9046serinus_canariaENSSCAP0000001702881.447474.0789
ENSG00000174780homo_sapiensENSP0000049512894.038785.544parus_majorENSPMJP0000001377494.319985.7997
ENSG00000174780homo_sapiensENSP0000049512893.889785.9911anolis_carolinensisENSACAP0000002324592.647184.8529
ENSG00000174780homo_sapiensENSP0000049512885.991174.0686neolamprologus_brichardiENSNBRP0000001883988.226375.9939
ENSG00000174780homo_sapiensENSP0000049512892.697585.0969naja_najaENSNNAP0000001903588.857181.5714
ENSG00000174780homo_sapiensENSP0000049512892.995585.544podarcis_muralisENSPMRP0000002843680.102773.6842
ENSG00000174780homo_sapiensENSP0000049512884.947877.3472geospiza_fortisENSGFOP0000001483393.289784.9427
ENSG00000174780homo_sapiensENSP0000049512894.336886.2891taeniopygia_guttataENSTGUP0000000494374.734468.3589
ENSG00000174780homo_sapiensENSP0000049512888.375676.4531erpetoichthys_calabaricusENSECRP0000003307188.772576.7964
ENSG00000174780homo_sapiensENSP0000049512888.524676.155kryptolebias_marmoratusENSKMAP0000000504388.789276.3827
ENSG00000174780homo_sapiensENSP0000049512893.442686.7362salvator_merianaeENSSMRP0000000745292.205985.5882
ENSG00000174780homo_sapiensENSP0000049512887.183375.1118oryzias_javanicusENSOJAP0000000311987.837875.6757
ENSG00000174780homo_sapiensENSP0000049512888.971776.6021amphilophus_citrinellusENSACIP0000000059889.104576.7164
ENSG00000174780homo_sapiensENSP0000049512889.269776.6021dicentrarchus_labraxENSDLAP0000502148089.004576.3744
ENSG00000174780homo_sapiensENSP0000049512888.077576.7511amphiprion_perculaENSAPEP0000000212088.605777.2114
ENSG00000174780homo_sapiensENSP0000049512887.779474.5156oryzias_sinensisENSOSIP0000004745988.305874.9625
ENSG00000174780homo_sapiensENSP0000049512822.801819.076oryzias_sinensisENSOSIP0000002627384.065970.3297
ENSG00000174780homo_sapiensENSP0000049512891.207283.6066pelodiscus_sinensisENSPSIP0000000313295.327187.3832
ENSG00000174780homo_sapiensENSP0000049512895.23186.2891gopherus_evgoodeiENSGEVP0000502374595.089386.1607
ENSG00000174780homo_sapiensENSP0000049512890.46281.5201gopherus_evgoodeiENSGEVP0000502090689.396280.5596
ENSG00000174780homo_sapiensENSP0000049512893.442685.2459chelonoidis_abingdoniiENSCABP0000002761289.189281.3656
ENSG00000174780homo_sapiensENSP0000049512889.418877.4963seriola_dumeriliENSSDUP0000001005487.719376.0234
ENSG00000174780homo_sapiensENSP0000049512889.567876.304cottoperca_gobioENSCGOP0000002233889.970176.6467
ENSG00000174780homo_sapiensENSP0000049512890.909183.1595struthio_camelus_australisENSSCUP0000002309795.163887.0515
ENSG00000174780homo_sapiensENSP0000049512894.634985.693anser_brachyrhynchusENSABRP0000000905794.213785.3116
ENSG00000174780homo_sapiensENSP0000049512888.822776.155gasterosteus_aculeatusENSGACP0000002210988.690576.0417
ENSG00000174780homo_sapiensENSP0000049512887.183375.2608cynoglossus_semilaevisENSCSEP0000000562085.526373.8304
ENSG00000174780homo_sapiensENSP0000049512889.269777.1982poecilia_formosaENSPFOP0000000349289.670777.5449
ENSG00000174780homo_sapiensENSP0000049512885.245972.4292myripristis_murdjanENSMMDP0000501162785.373172.5373
ENSG00000174780homo_sapiensENSP0000049512889.716876.304sander_luciopercaENSSLUP0000001759990.119876.6467
ENSG00000174780homo_sapiensENSP0000049512894.485886.1401strigops_habroptilaENSSHBP0000500759294.065385.7567
ENSG00000174780homo_sapiensENSP0000049512888.524677.1982amphiprion_ocellarisENSAOCP0000000743389.055577.6612
ENSG00000174780homo_sapiensENSP0000049512894.485886.2891terrapene_carolina_triunguisENSTMTP0000000433594.485886.2891
ENSG00000174780homo_sapiensENSP0000049512887.332375.4098hucho_huchoENSHHUP0000005653586.558374.7415
ENSG00000174780homo_sapiensENSP0000049512888.226576.4531hucho_huchoENSHHUP0000009101487.833876.1128
ENSG00000174780homo_sapiensENSP0000049512889.120777.0492betta_splendensENSBSLP0000002137589.52177.3952
ENSG00000174780homo_sapiensENSP0000049512888.822776.7511pygocentrus_nattereriENSPNAP0000003362989.624177.4436
ENSG00000174780homo_sapiensENSP0000049512883.904673.1744anabas_testudineusENSATEP0000006125586.882775.7716
ENSG00000174780homo_sapiensENSP0000049512864.232542.623ciona_savignyiENSCSAVP0000001922062.554441.5094
ENSG00000174780homo_sapiensENSP0000049512847.39230.4024ciona_savignyiENSCSAVP0000000933264.242441.2121
ENSG00000174780homo_sapiensENSP0000049512841.430721.3115saccharomyces_cerevisiaeYPL210C43.437522.3438
ENSG00000174780homo_sapiensENSP0000049512889.418877.6453seriola_lalandi_dorsalisENSSLDP0000002819287.719376.1696
ENSG00000174780homo_sapiensENSP0000049512830.104325.4844labrus_bergyltaENSLBEP0000002635786.695373.3906
ENSG00000174780homo_sapiensENSP0000049512889.418877.4963pundamilia_nyerereiENSPNYP0000000248589.820477.8443
ENSG00000174780homo_sapiensENSP0000049512888.077575.7079mastacembelus_armatusENSMAMP0000003741487.946475.5952
ENSG00000174780homo_sapiensENSP0000049512889.567877.1982stegastes_partitusENSSPAP0000001538489.970177.5449
ENSG00000174780homo_sapiensENSP0000049512887.183375.4098oncorhynchus_tshawytschaENSOTSP0000509641886.924275.1857
ENSG00000174780homo_sapiensENSP0000049512887.779476.006oncorhynchus_tshawytschaENSOTSP0000509320286.873275.2212
ENSG00000174780homo_sapiensENSP0000049512880.625969.7466acanthochromis_polyacanthusENSAPOP0000001625588.980376.9737
ENSG00000174780homo_sapiensENSP0000049512894.932986.4381aquila_chrysaetos_chrysaetosENSACCP0002000576194.510486.0534
ENSG00000174780homo_sapiensENSP0000049512888.971776.006nothobranchius_furzeriENSNFUP0001500556984.084571.831
ENSG00000174780homo_sapiensENSP0000049512882.265371.0879cyprinodon_variegatusENSCVAP0000002026090.640478.3251
ENSG00000174780homo_sapiensENSP0000049512887.928575.4098denticeps_clupeoidesENSDCDP0000001174974.494963.8889
ENSG00000174780homo_sapiensENSP0000049512888.077576.006larimichthys_croceaENSLCRP0000504243588.473176.3473
ENSG00000174780homo_sapiensENSP0000049512887.630475.5589takifugu_rubripesENSTRUP0000002470788.288376.1261
ENSG00000174780homo_sapiensENSP0000049512894.634986.4381ficedula_albicollisENSFALP0000000702479.177172.3192
ENSG00000174780homo_sapiensENSP0000049512888.375676.7511hippocampus_comesENSHCOP0000002445489.172977.4436
ENSG00000174780homo_sapiensENSP0000049512887.928577.0492cyprinus_carpio_carpioENSCCRP0000007599284.770174.2816
ENSG00000174780homo_sapiensENSP0000049512885.54474.5156cyprinus_carpio_carpioENSCCRP0000007600279.611669.3481
ENSG00000174780homo_sapiensENSP0000049512894.336886.5872coturnix_japonicaENSCJPP0000501250194.336886.5872
ENSG00000174780homo_sapiensENSP0000049512889.269777.1982poecilia_latipinnaENSPLAP0000001604989.670777.5449
ENSG00000174780homo_sapiensENSP0000049512884.798874.0686sinocyclocheilus_grahamiENSSGRP0000009554784.171673.5207
ENSG00000174780homo_sapiensENSP0000049512887.630476.304sinocyclocheilus_grahamiENSSGRP0000004927487.761276.4179
ENSG00000174780homo_sapiensENSP0000049512889.418877.1982maylandia_zebraENSMZEP0000500434685.348573.6842
ENSG00000174780homo_sapiensENSP0000049512889.120777.6453tetraodon_nigroviridisENSTNIP0000001605488.988177.5298
ENSG00000174780homo_sapiensENSP0000049512830.551425.4844paramormyrops_kingsleyaeENSPKIP0000002866289.130474.3478
ENSG00000174780homo_sapiensENSP0000049512824.739222.2057paramormyrops_kingsleyaeENSPKIP0000003752988.770179.6791
ENSG00000174780homo_sapiensENSP0000049512888.673678.3905scleropages_formosusENSSFOP0001500316289.473779.0977
ENSG00000174780homo_sapiensENSP0000049512890.46278.8376leptobrachium_leishanenseENSLLEP0000000117490.059378.4866
ENSG00000174780homo_sapiensENSP0000049512887.630475.7079scophthalmus_maximusENSSMAP0000004906787.240475.3709
ENSG00000174780homo_sapiensENSP0000049512887.332374.8137oryzias_melastigmaENSOMEP0000003501187.98875.3754

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0005047enables signal recognition particle binding1IPIHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005783located_in endoplasmic reticulum1IDAHomo_sapiens(9606)Component
GO:0005786part_of signal recognition particle, endoplasmic reticulum targeting2IBA,IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0006614involved_in SRP-dependent cotranslational protein targeting to membrane1IBAHomo_sapiens(9606)Process
GO:0008312enables 7S RNA binding2IBA,IMPHomo_sapiens(9606)Function
GO:0030911enables TPR domain binding1IPIHomo_sapiens(9606)Function
GO:0043022contributes_to ribosome binding2IBA,IMPHomo_sapiens(9606)Function
GO:0048500part_of signal recognition particle1IDAHomo_sapiens(9606)Component

Expression