Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000173627 Gene ID 403314 Accession 32152
Symbol APOBEC4 Alias C1orf169 Full Name apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
Status Confidence Length 7042 bases Strand Minus strand
Position 1 : 183646275 - 183653316 RNA binding domain APOBEC_N
Summary This gene encodes a member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases, which convert cytidine to uridine. Other AID/APOBEC family members are involved in mRNA editing, somatic hypermutation and recombination of immunoglobulin genes, and innate immunity to retroviral infection. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000310622 APOBEC_N PF08210 2.6e-31 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
APOBEC4-201 ENST00000308641 2782 367aa ENSP00000310622
APOBEC4-202 ENST00000481562 476 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
66479Lupus Erythematosus, Systemic6E-623273568

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000173627

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000173627homo_sapiensENSP0000031062298.365197.0027nomascus_leucogenysENSNLEP0000003983398.097896.7391
ENSG00000173627homo_sapiensENSP0000031062296.457894.8229pan_paniscusENSPPAP0000003057699.159797.479
ENSG00000173627homo_sapiensENSP0000031062297.547795.6403pongo_abeliiENSPPYP0000000048297.282695.3804
ENSG00000173627homo_sapiensENSP0000031062299.182698.3651pan_troglodytesENSPTRP0000008297999.182698.3651
ENSG00000173627homo_sapiensENSP0000031062299.727598.9101gorilla_gorillaENSGGOP0000003959399.456598.6413
ENSG00000173627homo_sapiensENSP0000031062272.207157.7657ornithorhynchus_anatinusENSOANP0000000159171.815757.4526
ENSG00000173627homo_sapiensENSP0000031062277.384265.1226sarcophilus_harrisiiENSSHAP0000001621875.935863.9037
ENSG00000173627homo_sapiensENSP0000031062288.283480.9264choloepus_hoffmanniENSCHOP0000001096388.283480.9264
ENSG00000173627homo_sapiensENSP0000031062289.645882.8338dasypus_novemcinctusENSDNOP0000002919489.402282.6087
ENSG00000173627homo_sapiensENSP0000031062294.822989.6458callithrix_jacchusENSCJAP0000005517394.308989.1599
ENSG00000173627homo_sapiensENSP0000031062295.912892.6431macaca_fascicularisENSMFAP0000005340496.969793.6639
ENSG00000173627homo_sapiensENSP0000031062295.367892.0981macaca_mulattaENSMMUP0000007386496.418793.1129
ENSG00000173627homo_sapiensENSP0000031062295.367892.6431papio_anubisENSPANP0000005172596.418793.6639
ENSG00000173627homo_sapiensENSP0000031062288.283481.4714tursiops_truncatusENSTTRP0000001401888.283481.4714
ENSG00000173627homo_sapiensENSP0000031062288.555982.0163vulpes_vulpesENSVVUP0000001227988.315281.7935
ENSG00000173627homo_sapiensENSP0000031062274.659461.0354mus_spretusMGP_SPRETEiJ_P002143174.254760.7046
ENSG00000173627homo_sapiensENSP0000031062289.100883.6512equus_asinusENSEASP0000500909789.344383.8798
ENSG00000173627homo_sapiensENSP0000031062285.013678.2016capra_hircusENSCHIP0000000897483.276.5333
ENSG00000173627homo_sapiensENSP0000031062289.645883.6512panthera_leoENSPLOP0000002933089.402283.4239
ENSG00000173627homo_sapiensENSP0000031062289.373384.1962ailuropoda_melanoleucaENSAMEP0000000261487.466782.4
ENSG00000173627homo_sapiensENSP0000031062287.738480.3815bos_indicus_hybridENSBIXP0000504344087.738480.3815
ENSG00000173627homo_sapiensENSP0000031062289.373383.6512equus_caballusENSECAP0000001717889.617583.8798
ENSG00000173627homo_sapiensENSP0000031062288.555982.5613canis_lupus_familiarisENSCAFP0084500671288.555982.5613
ENSG00000173627homo_sapiensENSP0000031062289.373383.3787panthera_pardusENSPPRP0000002451089.130483.1522
ENSG00000173627homo_sapiensENSP0000031062288.828382.5613balaenoptera_musculusENSBMSP0001000082788.828382.5613
ENSG00000173627homo_sapiensENSP0000031062289.373382.5613felis_catusENSFCAP0000001013489.130482.337
ENSG00000173627homo_sapiensENSP0000031062289.645883.9237ursus_americanusENSUAMP0000000574589.645883.9237
ENSG00000173627homo_sapiensENSP0000031062278.746666.485monodelphis_domesticaENSMODP0000005720578.108165.9459
ENSG00000173627homo_sapiensENSP0000031062271.934659.673monodelphis_domesticaENSMODP0000005459570.026558.0902
ENSG00000173627homo_sapiensENSP0000031062287.738480.3815bison_bison_bisonENSBBBP0000002687787.262979.9458
ENSG00000173627homo_sapiensENSP0000031062287.738480.654monodon_monocerosENSMMNP0001501328887.738480.654
ENSG00000173627homo_sapiensENSP0000031062285.831180.9264sus_scrofaENSSSCP0000001649786.065681.1475
ENSG00000173627homo_sapiensENSP0000031062275.204466.7575octodon_degusENSODEP0000001320881.415972.2714
ENSG00000173627homo_sapiensENSP0000031062286.103579.564ovis_aries_rambouilletENSOARP0002000661285.405478.9189
ENSG00000173627homo_sapiensENSP0000031062289.373383.6512ursus_maritimusENSUMAP0000002224889.373383.6512
ENSG00000173627homo_sapiensENSP0000031062287.738480.654delphinapterus_leucasENSDLEP0000002894387.738480.654
ENSG00000173627homo_sapiensENSP0000031062287.465981.1989physeter_catodonENSPCTP0000500388387.465981.1989
ENSG00000173627homo_sapiensENSP0000031062276.566862.6703mus_caroliMGP_CAROLIEiJ_P002036975.133761.4973
ENSG00000173627homo_sapiensENSP0000031062276.566861.8529mus_musculusENSMUSP0000006972375.133760.6952
ENSG00000173627homo_sapiensENSP0000031062278.746664.5777dipodomys_ordiiENSDORP0000000687982.571467.7143
ENSG00000173627homo_sapiensENSP0000031062285.286180.3815mustela_putorius_furoENSMPUP0000001166284.366679.5148
ENSG00000173627homo_sapiensENSP0000031062294.822991.0082chlorocebus_sabaeusENSCSAP0000001775395.867892.011
ENSG00000173627homo_sapiensENSP0000031062289.373380.9264tupaia_belangeriENSTBEP0000000555989.617581.1475
ENSG00000173627homo_sapiensENSP0000031062287.465980.109phocoena_sinusENSPSNP0000000447287.465980.109
ENSG00000173627homo_sapiensENSP0000031062283.651275.4768camelus_dromedariusENSCDRP0000500509183.879875.6831
ENSG00000173627homo_sapiensENSP0000031062289.373383.1063panthera_tigris_altaicaENSPTIP0000000251589.130482.8804
ENSG00000173627homo_sapiensENSP0000031062276.021862.3978rattus_norvegicusENSRNOP0000007709271.907259.0206
ENSG00000173627homo_sapiensENSP0000031062287.193582.5613prolemur_simusENSPSMP0000001830287.912183.2418
ENSG00000173627homo_sapiensENSP0000031062279.291569.2098peromyscus_maniculatus_bairdiiENSPEMP0000002154681.512671.1485
ENSG00000173627homo_sapiensENSP0000031062282.016374.3869bos_mutusENSBMUP0000002866783.84476.0446
ENSG00000173627homo_sapiensENSP0000031062275.204461.8529mus_spicilegusENSMSIP0000000847273.796860.6952
ENSG00000173627homo_sapiensENSP0000031062274.114461.0354cricetulus_griseus_chok1gshdENSCGRP0000100370479.069865.1163
ENSG00000173627homo_sapiensENSP0000031062287.465982.8338pteropus_vampyrusENSPVAP0000000103887.465982.8338
ENSG00000173627homo_sapiensENSP0000031062285.013677.9292myotis_lucifugusENSMLUP0000000222884.782677.7174
ENSG00000173627homo_sapiensENSP0000031062279.836568.3924vombatus_ursinusENSVURP0001001342177.718866.5782
ENSG00000173627homo_sapiensENSP0000031062287.193580.654rhinolophus_ferrumequinumENSRFEP0001003268486.720980.2168
ENSG00000173627homo_sapiensENSP0000031062286.37680.3815neovison_visonENSNVIP0000001529386.61280.6011
ENSG00000173627homo_sapiensENSP0000031062287.738480.3815bos_taurusENSBTAP0000005389587.738480.3815
ENSG00000173627homo_sapiensENSP0000031062278.746670.8447heterocephalus_glaber_femaleENSHGLP000000462738576.4706
ENSG00000173627homo_sapiensENSP0000031062288.555982.5613canis_lupus_dingoENSCAFP0002001953488.555982.5613
ENSG00000173627homo_sapiensENSP0000031062277.656766.485phascolarctos_cinereusENSPCIP0000000460877.445766.3043
ENSG00000173627homo_sapiensENSP0000031062270.027261.5804procavia_capensisENSPCAP0000001414669.83761.413
ENSG00000173627homo_sapiensENSP0000031062267.847459.673nannospalax_galiliENSNGAP0000001707079.299469.7452
ENSG00000173627homo_sapiensENSP0000031062288.010980.654bos_grunniensENSBGRP0000002184287.533980.2168
ENSG00000173627homo_sapiensENSP0000031062287.738480.654cervus_hanglu_yarkandensisENSCHYP0000003205587.738480.654
ENSG00000173627homo_sapiensENSP0000031062286.648581.1989catagonus_wagneriENSCWAP0000002671486.885281.4208
ENSG00000173627homo_sapiensENSP0000031062286.103578.4741otolemur_garnettiiENSOGAP0000000279187.052379.3388
ENSG00000173627homo_sapiensENSP0000031062286.103579.0191moschus_moschiferusENSMMSP0000001725186.103579.0191
ENSG00000173627homo_sapiensENSP0000031062276.566862.3978mus_pahariMGP_PahariEiJ_P007564875.133761.2299
ENSG00000173627homo_sapiensENSP0000031062245.776629.7003petromyzon_marinusENSPMAP0000000678545.901629.7814
ENSG00000173627homo_sapiensENSP0000031062258.583143.0518callorhinchus_miliiENSCMIP0000004483658.904143.2877
ENSG00000173627homo_sapiensENSP0000031062263.760250.1362latimeria_chalumnaeENSLACP000000164616551.1111
ENSG00000173627homo_sapiensENSP0000031062234.604923.9782lepisosteus_oculatusENSLOCP0000001265048.473333.5878
ENSG00000173627homo_sapiensENSP0000031062247.956434.0599clupea_harengusENSCHAP0000006151149.577535.2113
ENSG00000173627homo_sapiensENSP0000031062247.956435.4223oncorhynchus_kisutchENSOKIP0000508421850.429837.2493
ENSG00000173627homo_sapiensENSP0000031062249.591335.6948oncorhynchus_mykissENSOMYP0000013673550.980436.6947
ENSG00000173627homo_sapiensENSP0000031062261.852945.5041xenopus_tropicalisENSXETP0000003792762.707246.1326
ENSG00000173627homo_sapiensENSP0000031062265.122653.1335chrysemys_picta_belliiENSCPBP0000002191364.769652.8455
ENSG00000173627homo_sapiensENSP0000031062267.847451.7711sphenodon_punctatusENSSPUP0000001411967.297351.3514
ENSG00000173627homo_sapiensENSP0000031062262.397846.8665laticauda_laticaudataENSLLTP0000000111857.537743.2161
ENSG00000173627homo_sapiensENSP0000031062262.125347.4114notechis_scutatusENSNSUP0000001986860.158345.9103
ENSG00000173627homo_sapiensENSP0000031062261.307946.049pseudonaja_textilisENSPTXP0000000490065.789549.4152
ENSG00000173627homo_sapiensENSP0000031062255.585841.9619gallus_gallusENSGALP0001001581759.649145.0292
ENSG00000173627homo_sapiensENSP0000031062261.580450.4087anolis_carolinensisENSACAP0000001490665.129753.3141
ENSG00000173627homo_sapiensENSP0000031062262.670346.8665naja_najaENSNNAP0000002235165.155848.7252
ENSG00000173627homo_sapiensENSP0000031062262.125348.5014podarcis_muralisENSPMRP0000001139265.329551.0029
ENSG00000173627homo_sapiensENSP0000031062246.866533.2425erpetoichthys_calabaricusENSECRP0000003256553.918538.2445
ENSG00000173627homo_sapiensENSP0000031062259.67345.5041salvator_merianaeENSSMRP0000001594758.87144.8925
ENSG00000173627homo_sapiensENSP0000031062265.122651.4986chelonoidis_abingdoniiENSCABP0000000477462.239649.2188
ENSG00000173627homo_sapiensENSP0000031062255.585843.3242struthio_camelus_australisENSSCUP0000000655762.195148.4756
ENSG00000173627homo_sapiensENSP0000031062255.858342.7793strigops_habroptilaENSSHBP0000501735059.077845.245
ENSG00000173627homo_sapiensENSP0000031062261.852950.4087terrapene_carolina_triunguisENSTMTP0000000496660.857949.5979
ENSG00000173627homo_sapiensENSP0000031062261.852950.4087terrapene_carolina_triunguisENSTMTP0000001842860.857949.5979
ENSG00000173627homo_sapiensENSP0000031062246.59434.0599hucho_huchoENSHHUP0000006956449.854236.4431
ENSG00000173627homo_sapiensENSP0000031062246.866534.0599oncorhynchus_tshawytschaENSOTSP0000509037250.439936.6569
ENSG00000173627homo_sapiensENSP0000031062258.583143.5967aquila_chrysaetos_chrysaetosENSACCP0002000944160.224144.8179
ENSG00000173627homo_sapiensENSP0000031062254.223439.782coturnix_japonicaENSCJPP0000502748056.056341.1268
ENSG00000173627homo_sapiensENSP0000031062261.580446.8665leptobrachium_leishanenseENSLLEP0000001480262.087947.2527

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0006397involved_in mRNA processing1IEAHomo_sapiens(9606)Process
GO:0008270enables zinc ion binding1IEAHomo_sapiens(9606)Function
GO:0016814enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines1IEAHomo_sapiens(9606)Function

Expression