RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000173598	Gene ID	11163	Accession	8051
Symbol	NUDT4	Alias	DIPP2;NUDT4B;DIPP-2B;HDCMB47P;DIPP2beta;DIPP2alpha	Full Name	nudix hydrolase 4
Status	Confidence	Length	30264 bases	Strand	Plus strand
Position	12 : 93377883 - 93408146	RNA binding domain	N.A.
Summary	The protein encoded by this gene regulates the turnover of diphosphoinositol polyphosphates. The turnover of these high-energy diphosphoinositol polyphosphates represents a molecular switching activity with important regulatory consequences. Molecular switching by diphosphoinositol polyphosphates may contribute to regulating intracellular trafficking. Several alternatively spliced transcript variants have been described, but the full-length nature of some variants has not been determined. Isoforms DIPP2alpha and DIPP2beta are distinguishable from each other solely by DIPP2beta possessing one additional amino acid due to intron boundary skidding in alternate splicing. [provided by RefSeq, Jul 2008]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
NUDT4-201	ENST00000337179	9753	181aa	ENSP00000338352
NUDT4-202	ENST00000415493	9708	180aa	ENSP00000406612
NUDT4-207	ENST00000550056	531	95aa	ENSP00000448504
NUDT4-206	ENST00000549992	3607	128aa	ENSP00000449552
NUDT4-205	ENST00000548662	765	128aa	ENSP00000449724
NUDT4-204	ENST00000547014	1419	129aa	ENSP00000448032
NUDT4-203	ENST00000546925	569	112aa	ENSP00000448620

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
54593	Cryptoxanthins	2.3660000E-005	-

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000298	enables endopolyphosphatase activity	1	IBA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	1	IBA	Homo_sapiens(9606)	Component
GO:0005737	is_active_in cytoplasm	1	IBA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0008486	enables diphosphoinositol-polyphosphate diphosphatase activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0019722	involved_in calcium-mediated signaling	1	TAS	Homo_sapiens(9606)	Process
GO:0019935	involved_in cyclic-nucleotide-mediated signaling	1	TAS	Homo_sapiens(9606)	Process
GO:0030515	enables snoRNA binding	1	ISS	Homo_sapiens(9606)	Function
GO:0034431	enables bis(5-adenosyl)-hexaphosphatase activity	1	IBA	Homo_sapiens(9606)	Function
GO:0034432	enables bis(5-adenosyl)-pentaphosphatase activity	1	IBA	Homo_sapiens(9606)	Function
GO:0035556	involved_in intracellular signal transduction	1	NAS	Homo_sapiens(9606)	Process
GO:0046872	enables metal ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0052845	enables inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity	1	IEA	Homo_sapiens(9606)	Function
GO:0052848	enables inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity	1	IEA	Homo_sapiens(9606)	Function
GO:0071543	involved_in diphosphoinositol polyphosphate metabolic process	1	IBA	Homo_sapiens(9606)	Process
GO:0140933	NOT enables 5-(N(7)-methylguanosine 5-triphospho)-[mRNA] hydrolase activity	1	ISS	Homo_sapiens(9606)	Function
GO:1901907	involved_in diadenosine pentaphosphate catabolic process	1	IBA	Homo_sapiens(9606)	Process
GO:1901909	involved_in diadenosine hexaphosphate catabolic process	1	IBA	Homo_sapiens(9606)	Process
GO:1901911	involved_in adenosine 5-(hexahydrogen pentaphosphate) catabolic process	1	IBA	Homo_sapiens(9606)	Process