RBP Type	Canonical_RBPs
Diseases	Cancer
Drug	N.A.
Main interacting RNAs	mRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000172493	Gene ID	4299	Accession	7135
Symbol	AFF1	Alias	AF4;FEL;PBM1;MLLT2	Full Name	ALF transcription elongation factor 1
Status	Confidence	Length	206029 bases	Strand	Plus strand
Position	4 : 86935011 - 87141039	RNA binding domain	AF-4
Summary	This gene encodes a member of the AF4/ lymphoid nuclear protein related to the Fragile X E syndrome (FRAXE) family of proteins, which have been implicated in human childhood lymphoblastic leukemia, fragile chromosome X intellectual disability, and ataxia. It is the prevalent mixed-lineage leukemia fusion gene associated with spontaneous acute lymphoblastic leukemia. Members of this family have three conserved domains: an N-terminal homology domain, an AF4/ lymphoid nuclear protein domain, and a C-terminal homology domain. The protein functions as a regulator of RNA polymerase II-mediated transcription through elongation and chromatin remodeling functions. Through RNA interference screens, this gene has been shown to promote the expression of CD133, a plasma membrane glycoprotein required for leukemia cell survival. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000501252	AF-4	PF05110	1.2e-198	1
ENSP00000305689	AF-4	PF05110	1.6e-198	1
ENSP00000440843	AF-4	PF05110	1.6e-198	1
ENSP00000378578	AF-4	PF05110	1.6e-198	1
ENSP00000427593	AF-4	PF05110	2.4e-145	1
ENSP00000424483	AF-4	PF05110	1.4e-128	1
ENSP00000424483	AF-4	PF05110	1.4e-128	2
ENSP00000424881	AF-4	PF05110	2e-68	1
ENSP00000424766	AF-4	PF05110	2.5e-54	1
ENSP00000425755	AF-4	PF05110	3.6e-07	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
AFF1-205	ENST00000504956	1668	No protein	-
AFF1-202	ENST00000395146	9261	1218aa	ENSP00000378578
AFF1-206	ENST00000507468	1486	406aa	ENSP00000427593
AFF1-212	ENST00000674009	3460	1075aa	ENSP00000501252
AFF1-204	ENST00000503477	1478	417aa	ENSP00000424483
AFF1-209	ENST00000511996	480	No protein	-
AFF1-207	ENST00000511442	463	52aa	ENSP00000425755
AFF1-211	ENST00000544085	9625	1211aa	ENSP00000440843
AFF1-201	ENST00000307808	9390	1210aa	ENSP00000305689
AFF1-208	ENST00000511722	638	137aa	ENSP00000424766
AFF1-210	ENST00000514970	582	194aa	ENSP00000424881
AFF1-203	ENST00000503369	598	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
21988	Personality	9.788e-005	-
21995	Personality	9.788e-005	-
22280	Insulin	2.179e-005	-
22303	Insulin	1.337e-005	-
22317	Insulin	2.179e-005	-
63188	Triglycerides	1E-18	24097068
69369	Triglycerides	2E-10	25961943
79534	Alzheimer Disease	2E-7	23535033
80201	Lupus Erythematosus, Systemic	8E-9	22291604
90548	Triglycerides	3E-10	20864672
101694	Triglycerides	9E-12	20686565

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000172493	homo_sapiens	ENSP00000359489	42.4867	29.3669	homo_sapiens	ENSP00000378578	45.7307	31.6092
ENSG00000172493	homo_sapiens	ENSP00000265343	56.3199	39.123	homo_sapiens	ENSP00000378578	53.7767	37.3563
ENSG00000172493	homo_sapiens	ENSP00000500419	45.1876	30.3426	homo_sapiens	ENSP00000378578	45.4844	30.5419

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000172493	homo_sapiens	ENSP00000378578	94.8276	93.6782	nomascus_leucogenys	ENSNLEP00000011504	97.4684	96.2869
ENSG00000172493	homo_sapiens	ENSP00000378578	99.3432	99.0148	pan_paniscus	ENSPPAP00000011989	99.3432	99.0148
ENSG00000172493	homo_sapiens	ENSP00000378578	98.8506	98.4401	pongo_abelii	ENSPPYP00000035709	98.8506	98.4401
ENSG00000172493	homo_sapiens	ENSP00000378578	99.3432	98.9327	pan_troglodytes	ENSPTRP00000086127	99.3432	98.9327
ENSG00000172493	homo_sapiens	ENSP00000378578	99.9179	99.4253	gorilla_gorilla	ENSGGOP00000017471	99.8359	99.3437
ENSG00000172493	homo_sapiens	ENSP00000378578	72.4959	60.1806	ornithorhynchus_anatinus	ENSOANP00000021488	72.6749	60.3292
ENSG00000172493	homo_sapiens	ENSP00000378578	70.197	58.9491	sarcophilus_harrisii	ENSSHAP00000004790	69.3431	58.232
ENSG00000172493	homo_sapiens	ENSP00000378578	55.5008	46.9622	notamacropus_eugenii	ENSMEUP00000002814	59.3503	50.2195
ENSG00000172493	homo_sapiens	ENSP00000378578	67.1593	62.6437	choloepus_hoffmanni	ENSCHOP00000000035	69.9743	65.2695
ENSG00000172493	homo_sapiens	ENSP00000378578	63.4647	59.1133	dasypus_novemcinctus	ENSDNOP00000023051	89.261	83.1409
ENSG00000172493	homo_sapiens	ENSP00000378578	54.1872	49.0148	erinaceus_europaeus	ENSEEUP00000012487	55.7904	50.4649
ENSG00000172493	homo_sapiens	ENSP00000378578	81.1166	74.1379	echinops_telfairi	ENSETEP00000012082	81.25	74.2599
ENSG00000172493	homo_sapiens	ENSP00000378578	96.0591	93.1034	callithrix_jacchus	ENSCJAP00000011185	95.7447	92.7987
ENSG00000172493	homo_sapiens	ENSP00000378578	97.5369	96.7159	cercocebus_atys	ENSCATP00000032955	97.2973	96.4783
ENSG00000172493	homo_sapiens	ENSP00000378578	97.5369	96.6338	macaca_fascicularis	ENSMFAP00000036883	97.2973	96.3964
ENSG00000172493	homo_sapiens	ENSP00000378578	97.5369	96.6338	macaca_mulatta	ENSMMUP00000018502	97.2973	96.3964
ENSG00000172493	homo_sapiens	ENSP00000378578	97.7011	96.798	macaca_nemestrina	ENSMNEP00000014843	97.4611	96.5602
ENSG00000172493	homo_sapiens	ENSP00000378578	97.8654	96.9622	papio_anubis	ENSPANP00000048628	97.6249	96.724
ENSG00000172493	homo_sapiens	ENSP00000378578	97.619	96.798	mandrillus_leucophaeus	ENSMLEP00000029867	97.3792	96.5602
ENSG00000172493	homo_sapiens	ENSP00000378578	88.67	82.5944	tursiops_truncatus	ENSTTRP00000005279	89.478	83.3471
ENSG00000172493	homo_sapiens	ENSP00000378578	87.2742	82.0197	vulpes_vulpes	ENSVVUP00000012653	84.7687	79.6651
ENSG00000172493	homo_sapiens	ENSP00000378578	81.2808	72.9064	mus_spretus	MGP_SPRETEiJ_P0072064	81.0147	72.6678
ENSG00000172493	homo_sapiens	ENSP00000378578	87.931	81.5271	equus_asinus	ENSEASP00005038133	84.5972	78.436
ENSG00000172493	homo_sapiens	ENSP00000378578	88.8342	82.266	capra_hircus	ENSCHIP00000004242	88.1826	81.6626
ENSG00000172493	homo_sapiens	ENSP00000378578	27.0936	25.9442	loxodonta_africana	ENSLAFP00000021642	89.4309	85.6369
ENSG00000172493	homo_sapiens	ENSP00000378578	32.8407	30.2956	loxodonta_africana	ENSLAFP00000013327	81.9672	75.6148
ENSG00000172493	homo_sapiens	ENSP00000378578	82.8407	77.5862	panthera_leo	ENSPLOP00000009931	85.2916	79.8817
ENSG00000172493	homo_sapiens	ENSP00000378578	87.6026	82.4302	ailuropoda_melanoleuca	ENSAMEP00000003577	86.6775	81.5597
ENSG00000172493	homo_sapiens	ENSP00000378578	88.7521	82.1839	bos_indicus_hybrid	ENSBIXP00005012988	87.9577	81.4483
ENSG00000172493	homo_sapiens	ENSP00000378578	88.1773	80.7882	oryctolagus_cuniculus	ENSOCUP00000001817	84.3676	77.2977
ENSG00000172493	homo_sapiens	ENSP00000378578	88.1773	81.6092	equus_caballus	ENSECAP00000003273	84.8341	78.515
ENSG00000172493	homo_sapiens	ENSP00000378578	87.3563	82.3481	canis_lupus_familiaris	ENSCAFP00845020866	86.8571	81.8775
ENSG00000172493	homo_sapiens	ENSP00000378578	84.9754	79.8851	panthera_pardus	ENSPPRP00000002192	86.25	81.0833
ENSG00000172493	homo_sapiens	ENSP00000378578	90.5583	86.2069	marmota_marmota_marmota	ENSMMMP00000008336	91.3079	86.9205
ENSG00000172493	homo_sapiens	ENSP00000378578	89.3268	83.7438	balaenoptera_musculus	ENSBMSP00010002492	89.3268	83.7438
ENSG00000172493	homo_sapiens	ENSP00000378578	76.8473	67.2414	cavia_porcellus	ENSCPOP00000032202	77.7409	68.0233
ENSG00000172493	homo_sapiens	ENSP00000378578	87.6026	82.1018	felis_catus	ENSFCAP00000059075	85.2236	79.8722
ENSG00000172493	homo_sapiens	ENSP00000378578	71.5928	67.5698	ursus_americanus	ENSUAMP00000002068	85.8268	81.0039
ENSG00000172493	homo_sapiens	ENSP00000378578	71.1002	58.7028	monodelphis_domestica	ENSMODP00000037078	71.2757	58.8477
ENSG00000172493	homo_sapiens	ENSP00000378578	83.7438	77.5041	bison_bison_bison	ENSBBBP00000027365	87.6289	81.0997
ENSG00000172493	homo_sapiens	ENSP00000378578	88.8342	82.8407	monodon_monoceros	ENSMMNP00015027888	88.6885	82.7049
ENSG00000172493	homo_sapiens	ENSP00000378578	84.4828	77.5862	sus_scrofa	ENSSSCP00000066619	82.7836	76.0257
ENSG00000172493	homo_sapiens	ENSP00000378578	53.6946	46.6338	microcebus_murinus	ENSMICP00000035713	71.8681	62.4176
ENSG00000172493	homo_sapiens	ENSP00000378578	66.9951	58.7849	octodon_degus	ENSODEP00000009904	77.7884	68.2555
ENSG00000172493	homo_sapiens	ENSP00000378578	81.7734	74.7947	jaculus_jaculus	ENSJJAP00000022987	83.4171	76.2982
ENSG00000172493	homo_sapiens	ENSP00000378578	88.9984	82.1018	ovis_aries_rambouillet	ENSOARP00020027672	87.4899	80.7103
ENSG00000172493	homo_sapiens	ENSP00000378578	73.9737	69.1297	ursus_maritimus	ENSUMAP00000035394	82.8887	77.4609
ENSG00000172493	homo_sapiens	ENSP00000378578	84.3186	76.5189	ochotona_princeps	ENSOPRP00000015657	84.8059	76.9612
ENSG00000172493	homo_sapiens	ENSP00000378578	89.4089	83.6617	delphinapterus_leucas	ENSDLEP00000023372	88.7531	83.0481
ENSG00000172493	homo_sapiens	ENSP00000378578	89.491	83.8259	physeter_catodon	ENSPCTP00005001503	88.69	83.0757
ENSG00000172493	homo_sapiens	ENSP00000378578	81.3629	72.9064	mus_caroli	MGP_CAROLIEiJ_P0069399	80.7003	72.3127
ENSG00000172493	homo_sapiens	ENSP00000378578	81.1166	72.8243	mus_musculus	ENSMUSP00000031256	80.5873	72.3491
ENSG00000172493	homo_sapiens	ENSP00000378578	86.9458	80.2135	dipodomys_ordii	ENSDORP00000013051	89.0664	82.1699
ENSG00000172493	homo_sapiens	ENSP00000378578	87.1921	81.7734	mustela_putorius_furo	ENSMPUP00000002246	86.6232	81.2398
ENSG00000172493	homo_sapiens	ENSP00000378578	96.5517	94.6634	aotus_nancymaae	ENSANAP00000002114	96.2357	94.3535
ENSG00000172493	homo_sapiens	ENSP00000378578	96.0591	93.7603	saimiri_boliviensis_boliviensis	ENSSBOP00000038671	95.9016	93.6066
ENSG00000172493	homo_sapiens	ENSP00000378578	84.2365	77.0115	vicugna_pacos	ENSVPAP00000003724	85.7143	78.3626
ENSG00000172493	homo_sapiens	ENSP00000378578	96.9622	95.8949	chlorocebus_sabaeus	ENSCSAP00000000677	97.2817	96.2109
ENSG00000172493	homo_sapiens	ENSP00000378578	87.6026	81.8555	tupaia_belangeri	ENSTBEP00000006534	88.401	82.6015
ENSG00000172493	homo_sapiens	ENSP00000378578	81.1987	73.0706	mesocricetus_auratus	ENSMAUP00000008990	80.9329	72.8314
ENSG00000172493	homo_sapiens	ENSP00000378578	89.4089	83.6617	phocoena_sinus	ENSPSNP00000007080	89.7035	83.9374
ENSG00000172493	homo_sapiens	ENSP00000378578	85.5501	78.7356	camelus_dromedarius	ENSCDRP00005009402	85.2003	78.4137
ENSG00000172493	homo_sapiens	ENSP00000378578	58.3744	54.1051	carlito_syrichta	ENSTSYP00000001892	87.995	81.5594
ENSG00000172493	homo_sapiens	ENSP00000378578	72.2496	67.6519	panthera_tigris_altaica	ENSPTIP00000011445	88.4422	82.8141
ENSG00000172493	homo_sapiens	ENSP00000378578	80.7882	71.9212	rattus_norvegicus	ENSRNOP00000062389	80.4579	71.6271
ENSG00000172493	homo_sapiens	ENSP00000378578	83.8259	77.3399	prolemur_simus	ENSPSMP00000023930	80.5205	74.2902
ENSG00000172493	homo_sapiens	ENSP00000378578	80.3777	72.6601	microtus_ochrogaster	ENSMOCP00000019390	80.8423	73.0801
ENSG00000172493	homo_sapiens	ENSP00000378578	31.7734	27.8325	sorex_araneus	ENSSARP00000012033	53.8248	47.1488
ENSG00000172493	homo_sapiens	ENSP00000378578	82.1018	73.8095	peromyscus_maniculatus_bairdii	ENSPEMP00000001137	80.9717	72.7935
ENSG00000172493	homo_sapiens	ENSP00000378578	82.9228	76.4368	bos_mutus	ENSBMUP00000033737	87.6736	80.816
ENSG00000172493	homo_sapiens	ENSP00000378578	81.3629	72.7422	mus_spicilegus	ENSMSIP00000006494	78.8385	70.4853
ENSG00000172493	homo_sapiens	ENSP00000378578	82.7586	74.5484	cricetulus_griseus_chok1gshd	ENSCGRP00001015067	82.4877	74.3044
ENSG00000172493	homo_sapiens	ENSP00000378578	85.3859	80.2135	pteropus_vampyrus	ENSPVAP00000013625	86.2355	81.0116
ENSG00000172493	homo_sapiens	ENSP00000378578	86.6995	81.1987	myotis_lucifugus	ENSMLUP00000000270	87.0569	81.5334
ENSG00000172493	homo_sapiens	ENSP00000378578	70.4434	59.688	vombatus_ursinus	ENSVURP00010027860	70.8505	60.033
ENSG00000172493	homo_sapiens	ENSP00000378578	89.7373	83.908	rhinolophus_ferrumequinum	ENSRFEP00010005625	89.7373	83.908
ENSG00000172493	homo_sapiens	ENSP00000378578	87.6847	82.4302	neovison_vison	ENSNVIP00000032267	86.8999	81.6924
ENSG00000172493	homo_sapiens	ENSP00000378578	88.5879	82.0197	bos_taurus	ENSBTAP00000069534	87.8664	81.3518
ENSG00000172493	homo_sapiens	ENSP00000378578	74.22	65.353	heterocephalus_glaber_female	ENSHGLP00000001817	77.8639	68.5616
ENSG00000172493	homo_sapiens	ENSP00000378578	97.2085	96.0591	rhinopithecus_bieti	ENSRBIP00000016399	96.9697	95.8231
ENSG00000172493	homo_sapiens	ENSP00000378578	82.5944	77.5862	canis_lupus_dingo	ENSCAFP00020010134	84.6089	79.4786
ENSG00000172493	homo_sapiens	ENSP00000378578	92.3645	87.5205	sciurus_vulgaris	ENSSVLP00005019679	92.2888	87.4487
ENSG00000172493	homo_sapiens	ENSP00000378578	21.6749	17.8982	phascolarctos_cinereus	ENSPCIP00000014611	63.0072	52.0286
ENSG00000172493	homo_sapiens	ENSP00000378578	31.1166	25.2874	phascolarctos_cinereus	ENSPCIP00000048388	73.4496	59.6899
ENSG00000172493	homo_sapiens	ENSP00000378578	64.8604	60.3448	procavia_capensis	ENSPCAP00000005383	64.9671	60.4441
ENSG00000172493	homo_sapiens	ENSP00000378578	21.0181	19.376	nannospalax_galili	ENSNGAP00000012143	83.6601	77.1242
ENSG00000172493	homo_sapiens	ENSP00000378578	82.5944	76.0263	bos_grunniens	ENSBGRP00000025862	87.4023	80.4518
ENSG00000172493	homo_sapiens	ENSP00000378578	78.5714	68.3908	chinchilla_lanigera	ENSCLAP00000007900	78.1225	68
ENSG00000172493	homo_sapiens	ENSP00000378578	85.1396	79.064	cervus_hanglu_yarkandensis	ENSCHYP00000020451	83.8318	77.8496
ENSG00000172493	homo_sapiens	ENSP00000378578	82.5944	76.601	catagonus_wagneri	ENSCWAP00000026612	84.396	78.2718
ENSG00000172493	homo_sapiens	ENSP00000378578	91.5435	87.2742	ictidomys_tridecemlineatus	ENSSTOP00000027299	90.798	86.5635
ENSG00000172493	homo_sapiens	ENSP00000378578	83.9902	78.8177	otolemur_garnettii	ENSOGAP00000008612	84.2669	79.0774
ENSG00000172493	homo_sapiens	ENSP00000378578	54.3514	48.9327	otolemur_garnettii	ENSOGAP00000020363	82.8536	74.5932
ENSG00000172493	homo_sapiens	ENSP00000378578	90.9688	89.0805	cebus_imitator	ENSCCAP00000019643	94.7819	92.8144
ENSG00000172493	homo_sapiens	ENSP00000378578	92.0361	87.6847	urocitellus_parryii	ENSUPAP00010030494	91.2866	86.9707
ENSG00000172493	homo_sapiens	ENSP00000378578	88.4236	80.7882	moschus_moschiferus	ENSMMSP00000021656	87.7036	80.1303
ENSG00000172493	homo_sapiens	ENSP00000378578	97.2085	96.1412	rhinopithecus_roxellana	ENSRROP00000045657	96.9697	95.905
ENSG00000172493	homo_sapiens	ENSP00000378578	81.3629	73.2348	mus_pahari	MGP_PahariEiJ_P0032556	81.0303	72.9354
ENSG00000172493	homo_sapiens	ENSP00000378578	83.087	78.0788	propithecus_coquereli	ENSPCOP00000029303	85.3288	80.1855
ENSG00000172493	homo_sapiens	ENSP00000378578	36.2069	21.757	drosophila_melanogaster	FBpp0077318	26.3598	15.8398
ENSG00000172493	homo_sapiens	ENSP00000378578	33.9901	18.8834	ciona_intestinalis	ENSCINP00000012312	38.1919	21.2177
ENSG00000172493	homo_sapiens	ENSP00000378578	55.0903	42.5287	callorhinchus_milii	ENSCMIP00000013377	51.1823	39.5118
ENSG00000172493	homo_sapiens	ENSP00000378578	58.867	46.798	latimeria_chalumnae	ENSLACP00000008252	59.0123	46.9136
ENSG00000172493	homo_sapiens	ENSP00000378578	49.4253	36.6174	lepisosteus_oculatus	ENSLOCP00000004814	52.3478	38.7826
ENSG00000172493	homo_sapiens	ENSP00000378578	13.3005	10.3448	clupea_harengus	ENSCHAP00000062045	48.3582	37.6119
ENSG00000172493	homo_sapiens	ENSP00000378578	32.266	20.7718	clupea_harengus	ENSCHAP00000062042	46.2898	29.7998
ENSG00000172493	homo_sapiens	ENSP00000378578	36.0427	24.3842	carassius_auratus	ENSCARP00000104279	55.8524	37.7863
ENSG00000172493	homo_sapiens	ENSP00000378578	19.2939	12.1511	carassius_auratus	ENSCARP00000108675	58.75	37
ENSG00000172493	homo_sapiens	ENSP00000378578	40.8046	28.5714	astyanax_mexicanus	ENSAMXP00000016102	48.3463	33.8521
ENSG00000172493	homo_sapiens	ENSP00000378578	22.9885	15.353	ictalurus_punctatus	ENSIPUP00000022488	49.6454	33.156
ENSG00000172493	homo_sapiens	ENSP00000378578	15.9278	11.8227	ictalurus_punctatus	ENSIPUP00000022479	46.6346	34.6154
ENSG00000172493	homo_sapiens	ENSP00000378578	49.0969	36.4532	esox_lucius	ENSELUP00000039707	50.764	37.691
ENSG00000172493	homo_sapiens	ENSP00000378578	16.0099	12.8079	oncorhynchus_kisutch	ENSOKIP00005065586	56.5217	45.2174
ENSG00000172493	homo_sapiens	ENSP00000378578	44.7455	32.3481	oncorhynchus_kisutch	ENSOKIP00005019931	50.6035	36.5831
ENSG00000172493	homo_sapiens	ENSP00000378578	16.092	12.7258	oncorhynchus_mykiss	ENSOMYP00000032360	53.1165	42.0054
ENSG00000172493	homo_sapiens	ENSP00000378578	45.7307	33.0049	oncorhynchus_mykiss	ENSOMYP00000082386	51.3364	37.0507
ENSG00000172493	homo_sapiens	ENSP00000378578	46.9622	32.9228	salmo_salar	ENSSSAP00000026949	51.4851	36.0936
ENSG00000172493	homo_sapiens	ENSP00000378578	34.2365	23.9737	salmo_salar	ENSSSAP00000076542	50.9158	35.6532
ENSG00000172493	homo_sapiens	ENSP00000378578	14.4499	11.4122	salmo_trutta	ENSSTUP00000028920	49.7175	39.2655
ENSG00000172493	homo_sapiens	ENSP00000378578	35.3038	25.2053	salmo_trutta	ENSSTUP00000079389	48.0984	34.34
ENSG00000172493	homo_sapiens	ENSP00000378578	42.3645	28.3251	gadus_morhua	ENSGMOP00000043041	41.7138	27.8901
ENSG00000172493	homo_sapiens	ENSP00000378578	27.1757	18.8834	fundulus_heteroclitus	ENSFHEP00000002711	38.046	26.4368
ENSG00000172493	homo_sapiens	ENSP00000378578	38.7521	26.1084	poecilia_reticulata	ENSPREP00000005011	43.0657	29.0146
ENSG00000172493	homo_sapiens	ENSP00000378578	38.8342	26.2726	xiphophorus_maculatus	ENSXMAP00000004670	42.8054	28.9593
ENSG00000172493	homo_sapiens	ENSP00000378578	25.1232	15.6814	oryzias_latipes	ENSORLP00000008072	38.0124	23.7267
ENSG00000172493	homo_sapiens	ENSP00000378578	13.0542	10.4269	cyclopterus_lumpus	ENSCLMP00005003167	44.4134	35.4749
ENSG00000172493	homo_sapiens	ENSP00000378578	14.8604	9.44171	oreochromis_niloticus	ENSONIP00000080793	46.056	29.2621
ENSG00000172493	homo_sapiens	ENSP00000378578	41.2151	28.8998	haplochromis_burtoni	ENSHBUP00000024427	44.4641	31.178
ENSG00000172493	homo_sapiens	ENSP00000378578	41.2151	28.8177	astatotilapia_calliptera	ENSACLP00000004308	44.2291	30.9251
ENSG00000172493	homo_sapiens	ENSP00000378578	29.6388	20.1149	sparus_aurata	ENSSAUP00010022373	43.6518	29.6252
ENSG00000172493	homo_sapiens	ENSP00000378578	14.2857	11.0016	sparus_aurata	ENSSAUP00010022370	45.5497	35.0785
ENSG00000172493	homo_sapiens	ENSP00000378578	11.2479	8.45649	lates_calcarifer	ENSLCAP00010008408	41.1411	30.9309
ENSG00000172493	homo_sapiens	ENSP00000378578	58.2102	45.3202	xenopus_tropicalis	ENSXETP00000043162	61.1207	47.5862
ENSG00000172493	homo_sapiens	ENSP00000378578	72.0854	60.6732	chrysemys_picta_bellii	ENSCPBP00000006830	72.0854	60.6732
ENSG00000172493	homo_sapiens	ENSP00000378578	69.2118	57.225	sphenodon_punctatus	ENSSPUP00000002025	69.0418	57.0844
ENSG00000172493	homo_sapiens	ENSP00000378578	69.376	57.5534	crocodylus_porosus	ENSCPRP00005019115	67.7626	56.2149
ENSG00000172493	homo_sapiens	ENSP00000378578	18.7192	15.1067	laticauda_laticaudata	ENSLLTP00000013388	60.3175	48.6772
ENSG00000172493	homo_sapiens	ENSP00000378578	18.4729	15.1067	notechis_scutatus	ENSNSUP00000018991	59.5238	48.6772
ENSG00000172493	homo_sapiens	ENSP00000378578	36.5353	28.4893	notechis_scutatus	ENSNSUP00000018992	68.2515	53.2209
ENSG00000172493	homo_sapiens	ENSP00000378578	64.7783	51.8062	pseudonaja_textilis	ENSPTXP00000017344	64.9918	51.9769
ENSG00000172493	homo_sapiens	ENSP00000378578	63.711	50.4926	anas_platyrhynchos_platyrhynchos	ENSAPLP00000003634	67.8322	53.7587
ENSG00000172493	homo_sapiens	ENSP00000378578	13.8752	10.4269	gallus_gallus	ENSGALP00010006115	54.6926	41.1003
ENSG00000172493	homo_sapiens	ENSP00000378578	65.5172	50.4105	meleagris_gallopavo	ENSMGAP00000007784	66.1692	50.9121
ENSG00000172493	homo_sapiens	ENSP00000378578	62.6437	48.8506	serinus_canaria	ENSSCAP00000020769	62.5923	48.8105
ENSG00000172493	homo_sapiens	ENSP00000378578	62.8079	49.179	parus_major	ENSPMJP00000011408	58.1749	45.5513
ENSG00000172493	homo_sapiens	ENSP00000378578	18.7192	15.1067	naja_naja	ENSNNAP00000009070	60.3175	48.6772
ENSG00000172493	homo_sapiens	ENSP00000378578	34.8112	26.1905	podarcis_muralis	ENSPMRP00000031548	59.887	45.0565
ENSG00000172493	homo_sapiens	ENSP00000378578	19.2118	15.5993	podarcis_muralis	ENSPMRP00000031563	62.5668	50.8021
ENSG00000172493	homo_sapiens	ENSP00000378578	58.5386	45.3202	geospiza_fortis	ENSGFOP00000013175	61.1492	47.3413
ENSG00000172493	homo_sapiens	ENSP00000378578	62.6437	49.3432	taeniopygia_guttata	ENSTGUP00000002818	62.1842	48.9813
ENSG00000172493	homo_sapiens	ENSP00000378578	50.821	38.3415	erpetoichthys_calabaricus	ENSECRP00000019191	53.9669	40.7149
ENSG00000172493	homo_sapiens	ENSP00000378578	41.5435	28.0788	kryptolebias_marmoratus	ENSKMAP00000017608	44.8582	30.3191
ENSG00000172493	homo_sapiens	ENSP00000378578	67.734	53.6946	salvator_merianae	ENSSMRP00000016586	67.402	53.4314
ENSG00000172493	homo_sapiens	ENSP00000378578	33.3333	21.3465	oryzias_javanicus	ENSOJAP00000035638	40.3579	25.8449
ENSG00000172493	homo_sapiens	ENSP00000378578	28.8998	21.0181	amphilophus_citrinellus	ENSACIP00000027263	43.8903	31.9202
ENSG00000172493	homo_sapiens	ENSP00000378578	41.7077	29.5567	dicentrarchus_labrax	ENSDLAP00005029673	44.679	31.6623
ENSG00000172493	homo_sapiens	ENSP00000378578	42.4466	30.2135	amphiprion_percula	ENSAPEP00000026444	44.6845	31.8064
ENSG00000172493	homo_sapiens	ENSP00000378578	20.6897	13.8752	oryzias_sinensis	ENSOSIP00000015243	40.7108	27.3021
ENSG00000172493	homo_sapiens	ENSP00000378578	68.7192	56.8144	pelodiscus_sinensis	ENSPSIP00000003993	69.3455	57.3322
ENSG00000172493	homo_sapiens	ENSP00000378578	71.4286	60.1806	gopherus_evgoodei	ENSGEVP00005001158	71.4286	60.1806
ENSG00000172493	homo_sapiens	ENSP00000378578	66.5846	55.2545	chelonoidis_abingdonii	ENSCABP00000005016	68.7288	57.0339
ENSG00000172493	homo_sapiens	ENSP00000378578	26.4368	16.913	seriola_dumerili	ENSSDUP00000033101	43.9291	28.1037
ENSG00000172493	homo_sapiens	ENSP00000378578	39.9015	27.7504	cottoperca_gobio	ENSCGOP00000014102	43.3155	30.1248
ENSG00000172493	homo_sapiens	ENSP00000378578	70.4434	58.046	struthio_camelus_australis	ENSSCUP00000009819	70.9677	58.4781
ENSG00000172493	homo_sapiens	ENSP00000378578	63.3005	50.4105	anser_brachyrhynchus	ENSABRP00000004130	66.869	53.2524
ENSG00000172493	homo_sapiens	ENSP00000378578	41.2151	27.422	gasterosteus_aculeatus	ENSGACP00000021566	42.6508	28.3772
ENSG00000172493	homo_sapiens	ENSP00000378578	13.2184	9.60591	cynoglossus_semilaevis	ENSCSEP00000001342	43.3962	31.5364
ENSG00000172493	homo_sapiens	ENSP00000378578	39.2447	26.5189	poecilia_formosa	ENSPFOP00000004460	43.1408	29.1516
ENSG00000172493	homo_sapiens	ENSP00000378578	11.1658	9.1954	sander_lucioperca	ENSSLUP00000033266	42.3676	34.891
ENSG00000172493	homo_sapiens	ENSP00000378578	53.202	39.4089	strigops_habroptila	ENSSHBP00005017907	59.8338	44.3213
ENSG00000172493	homo_sapiens	ENSP00000378578	42.5287	30.2135	amphiprion_ocellaris	ENSAOCP00000029774	44.8097	31.8339
ENSG00000172493	homo_sapiens	ENSP00000378578	72.0033	60.7553	terrapene_carolina_triunguis	ENSTMTP00000004826	72.1217	60.8553
ENSG00000172493	homo_sapiens	ENSP00000378578	30.9524	22.9064	hucho_hucho	ENSHHUP00000090049	47.3024	35.0063
ENSG00000172493	homo_sapiens	ENSP00000378578	44.4171	31.445	hucho_hucho	ENSHHUP00000071870	51.3283	36.3378
ENSG00000172493	homo_sapiens	ENSP00000378578	16.5025	11.4122	hucho_hucho	ENSHHUP00000091116	67	46.3333
ENSG00000172493	homo_sapiens	ENSP00000378578	40.5583	28.1609	betta_splendens	ENSBSLP00000020968	43.4859	30.1937
ENSG00000172493	homo_sapiens	ENSP00000378578	12.7258	9.68801	anabas_testudineus	ENSATEP00000045179	42.6997	32.5069
ENSG00000172493	homo_sapiens	ENSP00000378578	44.335	30.9524	seriola_lalandi_dorsalis	ENSSLDP00000008603	44.7761	31.2604
ENSG00000172493	homo_sapiens	ENSP00000378578	41.954	28.4893	labrus_bergylta	ENSLBEP00000022036	44.0897	29.9396
ENSG00000172493	homo_sapiens	ENSP00000378578	12.4795	9.52381	mastacembelus_armatus	ENSMAMP00000024098	41.7582	31.8681
ENSG00000172493	homo_sapiens	ENSP00000378578	42.3645	29.4745	stegastes_partitus	ENSSPAP00000005118	44.6753	31.0823
ENSG00000172493	homo_sapiens	ENSP00000378578	45.3202	32.3481	oncorhynchus_tshawytscha	ENSOTSP00005008686	50.0907	35.7532
ENSG00000172493	homo_sapiens	ENSP00000378578	44.335	32.0197	oncorhynchus_tshawytscha	ENSOTSP00005080980	50.9915	36.8272
ENSG00000172493	homo_sapiens	ENSP00000378578	42.775	30.3777	acanthochromis_polyacanthus	ENSAPOP00000001656	45.1082	32.0346
ENSG00000172493	homo_sapiens	ENSP00000378578	69.376	55.5008	aquila_chrysaetos_chrysaetos	ENSACCP00020001203	69.7195	55.7756
ENSG00000172493	homo_sapiens	ENSP00000378578	12.3153	9.2775	nothobranchius_furzeri	ENSNFUP00015006040	42.9799	32.3782
ENSG00000172493	homo_sapiens	ENSP00000378578	26.6831	16.5025	nothobranchius_furzeri	ENSNFUP00015006014	42.7632	26.4474
ENSG00000172493	homo_sapiens	ENSP00000378578	38.1773	25.78	cyprinodon_variegatus	ENSCVAP00000028522	43.9509	29.6786
ENSG00000172493	homo_sapiens	ENSP00000378578	40.6404	29.3924	denticeps_clupeoides	ENSDCDP00000063452	47.7799	34.556
ENSG00000172493	homo_sapiens	ENSP00000378578	44.7455	31.5271	larimichthys_crocea	ENSLCRP00005014760	44.7455	31.5271
ENSG00000172493	homo_sapiens	ENSP00000378578	40.3941	28.4072	takifugu_rubripes	ENSTRUP00000035831	42.4138	29.8276
ENSG00000172493	homo_sapiens	ENSP00000378578	62.6437	49.5895	ficedula_albicollis	ENSFALP00000005794	61.9318	49.026
ENSG00000172493	homo_sapiens	ENSP00000378578	37.5205	25.041	hippocampus_comes	ENSHCOP00000027958	44.1546	29.4686
ENSG00000172493	homo_sapiens	ENSP00000378578	36.6174	25.3695	cyprinus_carpio_carpio	ENSCCRP00000181079	56.6709	39.263
ENSG00000172493	homo_sapiens	ENSP00000378578	37.7668	25.8621	cyprinus_carpio_carpio	ENSCCRP00000172645	54.2453	37.1462
ENSG00000172493	homo_sapiens	ENSP00000378578	64.7783	49.2611	coturnix_japonica	ENSCJPP00005011698	65.75	50
ENSG00000172493	homo_sapiens	ENSP00000378578	35.9606	23.6453	poecilia_latipinna	ENSPLAP00000010064	41.8338	27.5072
ENSG00000172493	homo_sapiens	ENSP00000378578	24.5484	16.1741	sinocyclocheilus_grahami	ENSSGRP00000028632	55.3704	36.4815
ENSG00000172493	homo_sapiens	ENSP00000378578	41.2972	28.8998	maylandia_zebra	ENSMZEP00005027418	44.3172	31.0132
ENSG00000172493	homo_sapiens	ENSP00000378578	39.9836	26.9294	tetraodon_nigroviridis	ENSTNIP00000010346	40.8557	27.5168
ENSG00000172493	homo_sapiens	ENSP00000378578	45.977	32.9228	paramormyrops_kingsleyae	ENSPKIP00000024668	48.738	34.8999
ENSG00000172493	homo_sapiens	ENSP00000378578	47.7011	34.4828	scleropages_formosus	ENSSFOP00015034093	51.2798	37.0697
ENSG00000172493	homo_sapiens	ENSP00000378578	55.5008	41.954	leptobrachium_leishanense	ENSLLEP00000001073	58.9878	44.5899
ENSG00000172493	homo_sapiens	ENSP00000378578	27.2578	17.734	scophthalmus_maximus	ENSSMAP00000011463	41.8136	27.204
ENSG00000172493	homo_sapiens	ENSP00000378578	13.8752	10.6732	scophthalmus_maximus	ENSSMAP00000011515	45.4301	34.9462
ENSG00000172493	homo_sapiens	ENSP00000378578	35.7964	23.6453	oryzias_melastigma	ENSOMEP00000024894	46.9322	31.0011

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0008023	part_of transcription elongation factor complex	1	IDA	Homo_sapiens(9606)	Component
GO:0010468	involved_in regulation of gene expression	1	IBA	Homo_sapiens(9606)	Process
GO:0032783	part_of super elongation complex	1	IBA	Homo_sapiens(9606)	Component