RBP Type
Canonical_RBPs
Diseases
Drug
N.A.
Main interacting RNAs
mRNA
Moonlighting functions
N.A.
Localizations
N.A.
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000172409 Gene ID
10978 Accession
16999
Symbol
CLP1
Alias
HEAB;hClp1
Full Name
cleavage factor polyribonucleotide kinase subunit 1
Status
Confidence
Length
13678 bases
Strand
Plus strand
Position
11 : 57648188 - 57661865
RNA binding domain
Clp1
Summary
This gene encodes a member of the Clp1 family. The encoded protein is a multifunctional kinase which is a component of the tRNA splicing endonuclease complex and a component of the pre-mRNA cleavage complex II. This protein is implicated in tRNA, mRNA, and siRNA maturation. Mutations in this gene are associated with pontocerebellar hypoplasia type 10 (PCH10). Alternatively splice transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000304704
Clp1
PF06807 1.1e-30
1
ENSP00000434995
Clp1
PF06807 1.5e-30
1
ENSP00000436066
Clp1
PF06807 1.5e-30
1
ENSP00000506714
Clp1
PF06807 1.5e-30
1
ENSP00000433406
Clp1
PF06807 1.5e-30
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
25266383 Structures of bacterial polynucleotide kinase in a michaelis complex with nucleoside triphosphate (NTP)-Mg2+ and 5'-OH RNA and a mixed substrate-product complex with NTP-Mg2+ and a 5'-phosphorylated oligonucleotide.
Ushati Das
2014-12-01
Journal of bacteriology
29052333 Label-Free Quantitative Proteomic Analysis of Differentially Expressed Membrane Proteins of Pulmonary Alveolar Macrophages Infected with Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus and Its Attenuated Strain.
Zehui Qu
2017-12-01
Proteomics
35049972 The Fission Yeast Cell Integrity Pathway: A Functional Hub for Cell Survival upon Stress and Beyond.
José Cansado
2021-12-30
Journal of fungi (Basel, Switzerland)
21993299 The interaction of Pcf11 and Clp1 is needed for mRNA 3'-end formation and is modulated by amino acids in the ATP-binding site.
A Mohamed Ghazy
2012-02-01
Nucleic acids research
32338592 Aire-dependent genes undergo Clp1-mediated 3'UTR shortening associated with higher transcript stability in the thymus.
Clotilde Guyon
2020-04-29
eLife
32295865 Requirement for cleavage factor IIm in the control of alternative polyadenylation in breast cancer cells.
E Rachael Turner
2020-08-01
RNA (New York, N.Y.)
31288032 Nol9 Is a Spatial Regulator for the Human ITS2 Pre-rRNA Endonuclease-Kinase Complex.
Jacob Gordon
2019-09-06
Journal of molecular biology
26539891 Genes that Affect Brain Structure and Function Identified by Rare Variant Analyses of Mendelian Neurologic Disease.
Ender Karaca
2015-11-04
Neuron
33526057 Alternative polyadenylation: methods, mechanism, function, and role in cancer.
Yi Zhang
2021-02-01
Journal of experimental & clinical cancer research : CR
35756640 PCF11, a Novel CD44-Downstream Transcriptional Target, Linking Its 3'-End Polyadenylation Function to Tumor Cell Metastasis.
Maryam Al-Mansoob
2022-01-01
Frontiers in oncology
30139799 Reconstitution of mammalian cleavage factor II involved in 3' processing of mRNA precursors.
Peter Schäfer
2018-12-01
RNA (New York, N.Y.)
Name
Transcript ID
bp
Protein
Translation ID
CLP1-207
ENST00000681650
1931
425aa
ENSP00000506714
CLP1-203
ENST00000529430
1778
436aa
ENSP00000433406
CLP1-204
ENST00000529773
996
210aa
ENSP00000435287
CLP1-206
ENST00000533905
553
132aa
ENSP00000431744
CLP1-202
ENST00000525602
1392
425aa
ENSP00000436066
CLP1-205
ENST00000533682
1828
425aa
ENSP00000434995
CLP1-201
ENST00000302731
1634
361aa
ENSP00000304704
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000172409 homo_sapiens ENSP00000366934 21.7949 11.9658 homo_sapiens ENSP00000434995 36 19.7647
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000172409 homo_sapiens ENSP00000434995 75.0588 75.0588 nomascus_leucogenys ENSNLEP00000015549 100 100 ENSG00000172409 homo_sapiens ENSP00000434995 100 100 pan_paniscus ENSPPAP00000037543 97.4771 97.4771 ENSG00000172409 homo_sapiens ENSP00000434995 100 100 pongo_abelii ENSPPYP00000003754 97.4771 97.4771 ENSG00000172409 homo_sapiens ENSP00000434995 100 100 pan_troglodytes ENSPTRP00000062766 100 100 ENSG00000172409 homo_sapiens ENSP00000434995 100 100 gorilla_gorilla ENSGGOP00000048315 97.4771 97.4771 ENSG00000172409 homo_sapiens ENSP00000434995 98.8235 97.6471 ornithorhynchus_anatinus ENSOANP00000040370 98.8235 97.6471 ENSG00000172409 homo_sapiens ENSP00000434995 98.5882 97.4118 notamacropus_eugenii ENSMEUP00000009991 98.5882 97.4118 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.2941 dasypus_novemcinctus ENSDNOP00000032723 89.6406 89.2178 ENSG00000172409 homo_sapiens ENSP00000434995 99.2941 98.5882 erinaceus_europaeus ENSEEUP00000011614 99.2941 98.5882 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.7647 echinops_telfairi ENSETEP00000002467 99.7647 99.7647 ENSG00000172409 homo_sapiens ENSP00000434995 84.9412 84.9412 callithrix_jacchus ENSCJAP00000016076 100 100 ENSG00000172409 homo_sapiens ENSP00000434995 100 100 cercocebus_atys ENSCATP00000044279 97.4771 97.4771 ENSG00000172409 homo_sapiens ENSP00000434995 100 100 macaca_fascicularis ENSMFAP00000039778 97.4771 97.4771 ENSG00000172409 homo_sapiens ENSP00000434995 100 100 macaca_mulatta ENSMMUP00000076974 100 100 ENSG00000172409 homo_sapiens ENSP00000434995 100 100 macaca_nemestrina ENSMNEP00000000133 100 100 ENSG00000172409 homo_sapiens ENSP00000434995 100 100 papio_anubis ENSPANP00000004734 97.4771 97.4771 ENSG00000172409 homo_sapiens ENSP00000434995 100 100 mandrillus_leucophaeus ENSMLEP00000039044 97.4771 97.4771 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.0588 tursiops_truncatus ENSTTRP00000001967 99.7647 99.0588 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.5294 vulpes_vulpes ENSVVUP00000023399 96.5831 96.3554 ENSG00000172409 homo_sapiens ENSP00000434995 99.2941 98.5882 mus_spretus MGP_SPRETEiJ_P0054722 99.2941 98.5882 ENSG00000172409 homo_sapiens ENSP00000434995 100 99.7647 equus_asinus ENSEASP00005042207 100 99.7647 ENSG00000172409 homo_sapiens ENSP00000434995 99.5294 98.8235 capra_hircus ENSCHIP00000027671 99.5294 98.8235 ENSG00000172409 homo_sapiens ENSP00000434995 99.5294 99.5294 loxodonta_africana ENSLAFP00000012480 99.5294 99.5294 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.2941 panthera_leo ENSPLOP00000014437 66.877 66.5615 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.5294 ailuropoda_melanoleuca ENSAMEP00000015325 99.7647 99.5294 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.5294 bos_indicus_hybrid ENSBIXP00005040879 99.7647 99.5294 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.5294 oryctolagus_cuniculus ENSOCUP00000006090 99.7647 99.5294 ENSG00000172409 homo_sapiens ENSP00000434995 100 99.7647 equus_caballus ENSECAP00000009422 90.4255 90.2128 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.5294 canis_lupus_familiaris ENSCAFP00845028247 99.7647 99.5294 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.2941 panthera_pardus ENSPPRP00000012659 99.7647 99.2941 ENSG00000172409 homo_sapiens ENSP00000434995 100 99.7647 marmota_marmota_marmota ENSMMMP00000020048 100 99.7647 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.2941 balaenoptera_musculus ENSBMSP00010008331 99.7647 99.2941 ENSG00000172409 homo_sapiens ENSP00000434995 97.4118 97.4118 cavia_porcellus ENSCPOP00000011296 99.2806 99.2806 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.2941 felis_catus ENSFCAP00000030736 66.877 66.5615 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.5294 ursus_americanus ENSUAMP00000014169 99.7647 99.5294 ENSG00000172409 homo_sapiens ENSP00000434995 98.5882 97.4118 monodelphis_domestica ENSMODP00000033349 98.5882 97.4118 ENSG00000172409 homo_sapiens ENSP00000434995 79.7647 78.3529 monodelphis_domestica ENSMODP00000055901 96.8571 95.1429 ENSG00000172409 homo_sapiens ENSP00000434995 98.5882 97.4118 monodelphis_domestica ENSMODP00000025124 96.7667 95.612 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.5294 bison_bison_bison ENSBBBP00000006275 99.7647 99.5294 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.0588 monodon_monoceros ENSMMNP00015030222 99.7647 99.0588 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.5294 sus_scrofa ENSSSCP00000032032 99.7647 99.5294 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.5294 microcebus_murinus ENSMICP00000004460 98.1481 97.9167 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.7647 octodon_degus ENSODEP00000015461 99.7647 99.7647 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.0588 jaculus_jaculus ENSJJAP00000024126 99.7647 99.0588 ENSG00000172409 homo_sapiens ENSP00000434995 99.5294 99.0588 ovis_aries_rambouillet ENSOARP00020015854 99.5294 99.0588 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.5294 ursus_maritimus ENSUMAP00000025133 99.7647 99.5294 ENSG00000172409 homo_sapiens ENSP00000434995 70.1176 69.6471 ochotona_princeps ENSOPRP00000006706 100 99.3289 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.0588 delphinapterus_leucas ENSDLEP00000003304 99.7647 99.0588 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.2941 physeter_catodon ENSPCTP00005030562 99.7647 99.2941 ENSG00000172409 homo_sapiens ENSP00000434995 99.2941 98.5882 mus_caroli MGP_CAROLIEiJ_P0052632 99.2941 98.5882 ENSG00000172409 homo_sapiens ENSP00000434995 99.2941 98.5882 mus_musculus ENSMUSP00000028475 99.2941 98.5882 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.2941 dipodomys_ordii ENSDORP00000013816 99.7647 99.2941 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.5294 mustela_putorius_furo ENSMPUP00000000266 99.7647 99.5294 ENSG00000172409 homo_sapiens ENSP00000434995 100 100 aotus_nancymaae ENSANAP00000034684 97.4771 97.4771 ENSG00000172409 homo_sapiens ENSP00000434995 100 100 saimiri_boliviensis_boliviensis ENSSBOP00000032683 100 100 ENSG00000172409 homo_sapiens ENSP00000434995 78.8235 75.7647 saimiri_boliviensis_boliviensis ENSSBOP00000002040 82.9208 79.703 ENSG00000172409 homo_sapiens ENSP00000434995 53.8824 53.4118 vicugna_pacos ENSVPAP00000011681 68.5629 67.9641 ENSG00000172409 homo_sapiens ENSP00000434995 100 100 chlorocebus_sabaeus ENSCSAP00000002296 100 100 ENSG00000172409 homo_sapiens ENSP00000434995 99.0588 98.3529 tupaia_belangeri ENSTBEP00000008616 99.2924 98.5849 ENSG00000172409 homo_sapiens ENSP00000434995 98.8235 98.1176 mesocricetus_auratus ENSMAUP00000017361 98.8235 98.1176 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.0588 phocoena_sinus ENSPSNP00000021092 99.7647 99.0588 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.2941 camelus_dromedarius ENSCDRP00005002112 99.7647 99.2941 ENSG00000172409 homo_sapiens ENSP00000434995 99.5294 99.5294 carlito_syrichta ENSTSYP00000006217 98.1439 98.1439 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.2941 panthera_tigris_altaica ENSPTIP00000017416 99.7647 99.2941 ENSG00000172409 homo_sapiens ENSP00000434995 99.2941 98.5882 rattus_norvegicus ENSRNOP00000009726 99.2941 98.5882 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.5294 prolemur_simus ENSPSMP00000008516 96.5831 96.3554 ENSG00000172409 homo_sapiens ENSP00000434995 99.5294 99.0588 microtus_ochrogaster ENSMOCP00000005942 99.5294 99.0588 ENSG00000172409 homo_sapiens ENSP00000434995 52 52 sorex_araneus ENSSARP00000002211 99.1031 99.1031 ENSG00000172409 homo_sapiens ENSP00000434995 99.5294 99.0588 peromyscus_maniculatus_bairdii ENSPEMP00000010118 99.5294 99.0588 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.5294 bos_mutus ENSBMUP00000026123 99.7647 99.5294 ENSG00000172409 homo_sapiens ENSP00000434995 99.2941 98.5882 mus_spicilegus ENSMSIP00000002907 99.2941 98.5882 ENSG00000172409 homo_sapiens ENSP00000434995 99.2941 98.8235 cricetulus_griseus_chok1gshd ENSCGRP00001002141 99.2941 98.8235 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.5294 pteropus_vampyrus ENSPVAP00000015348 99.7647 99.5294 ENSG00000172409 homo_sapiens ENSP00000434995 99.2941 99.0588 myotis_lucifugus ENSMLUP00000007211 99.2941 99.0588 ENSG00000172409 homo_sapiens ENSP00000434995 98.8235 97.1765 vombatus_ursinus ENSVURP00010007731 98.5916 96.9484 ENSG00000172409 homo_sapiens ENSP00000434995 99.5294 99.0588 rhinolophus_ferrumequinum ENSRFEP00010005722 99.5294 99.0588 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.5294 neovison_vison ENSNVIP00000020943 99.7647 99.5294 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.5294 bos_taurus ENSBTAP00000062480 99.7647 99.5294 ENSG00000172409 homo_sapiens ENSP00000434995 92.4706 92.2353 heterocephalus_glaber_female ENSHGLP00000055817 98.25 98 ENSG00000172409 homo_sapiens ENSP00000434995 100 100 rhinopithecus_bieti ENSRBIP00000003853 100 100 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.5294 canis_lupus_dingo ENSCAFP00020000937 99.7647 99.5294 ENSG00000172409 homo_sapiens ENSP00000434995 100 99.7647 sciurus_vulgaris ENSSVLP00005020483 100 99.7647 ENSG00000172409 homo_sapiens ENSP00000434995 98.5882 96.9412 phascolarctos_cinereus ENSPCIP00000015294 98.3568 96.7136 ENSG00000172409 homo_sapiens ENSP00000434995 74.3529 73.8824 procavia_capensis ENSPCAP00000001068 74.5283 74.0566 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.2941 nannospalax_galili ENSNGAP00000004581 99.7647 99.2941 ENSG00000172409 homo_sapiens ENSP00000434995 99.5294 99.2941 bos_grunniens ENSBGRP00000009612 99.7642 99.5283 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.7647 chinchilla_lanigera ENSCLAP00000005773 99.7647 99.7647 ENSG00000172409 homo_sapiens ENSP00000434995 66.5882 61.6471 cervus_hanglu_yarkandensis ENSCHYP00000013661 63.029 58.3519 ENSG00000172409 homo_sapiens ENSP00000434995 99.5294 99.2941 catagonus_wagneri ENSCWAP00000008315 99.5294 99.2941 ENSG00000172409 homo_sapiens ENSP00000434995 100 99.7647 ictidomys_tridecemlineatus ENSSTOP00000020830 100 99.7647 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.2941 otolemur_garnettii ENSOGAP00000004026 99.7647 99.2941 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.5294 cebus_imitator ENSCCAP00000028096 99.7647 99.5294 ENSG00000172409 homo_sapiens ENSP00000434995 100 99.7647 urocitellus_parryii ENSUPAP00010025394 100 99.7647 ENSG00000172409 homo_sapiens ENSP00000434995 99.5294 98.3529 moschus_moschiferus ENSMMSP00000000049 99.5294 98.3529 ENSG00000172409 homo_sapiens ENSP00000434995 100 100 rhinopithecus_roxellana ENSRROP00000031117 97.4771 97.4771 ENSG00000172409 homo_sapiens ENSP00000434995 99.2941 98.3529 mus_pahari MGP_PahariEiJ_P0063627 99.2941 98.3529 ENSG00000172409 homo_sapiens ENSP00000434995 99.7647 99.5294 propithecus_coquereli ENSPCOP00000000192 98.1481 97.9167 ENSG00000172409 homo_sapiens ENSP00000434995 66.5882 47.7647 caenorhabditis_elegans F59A2.4a.1 66.1215 47.4299 ENSG00000172409 homo_sapiens ENSP00000434995 73.1765 55.2941 drosophila_melanogaster FBpp0086820 73.5225 55.5556 ENSG00000172409 homo_sapiens ENSP00000434995 81.6471 63.2941 ciona_intestinalis ENSCINP00000007796 80.6977 62.5581 ENSG00000172409 homo_sapiens ENSP00000434995 88.4706 76.4706 petromyzon_marinus ENSPMAP00000007403 88.6792 76.6509 ENSG00000172409 homo_sapiens ENSP00000434995 85.1765 70.3529 eptatretus_burgeri ENSEBUP00000018654 85.1765 70.3529 ENSG00000172409 homo_sapiens ENSP00000434995 94.1176 85.6471 latimeria_chalumnae ENSLACP00000003547 94.3396 85.8491 ENSG00000172409 homo_sapiens ENSP00000434995 66.3529 58.1176 lepisosteus_oculatus ENSLOCP00000009807 87.5776 76.7081 ENSG00000172409 homo_sapiens ENSP00000434995 89.6471 78.5882 clupea_harengus ENSCHAP00000000663 85.0446 74.5536 ENSG00000172409 homo_sapiens ENSP00000434995 89.4118 78.8235 danio_rerio ENSDARP00000087664 85.7788 75.6208 ENSG00000172409 homo_sapiens ENSP00000434995 75.5294 63.7647 carassius_auratus ENSCARP00000113838 83.1606 70.2073 ENSG00000172409 homo_sapiens ENSP00000434995 90.1176 78.5882 carassius_auratus ENSCARP00000103785 86.0674 75.0562 ENSG00000172409 homo_sapiens ENSP00000434995 89.6471 78.1176 astyanax_mexicanus ENSAMXP00000028627 85.618 74.6067 ENSG00000172409 homo_sapiens ENSP00000434995 89.6471 78.8235 ictalurus_punctatus ENSIPUP00000024036 84.8552 74.6102 ENSG00000172409 homo_sapiens ENSP00000434995 89.1765 78.8235 esox_lucius ENSELUP00000025394 85.553 75.6208 ENSG00000172409 homo_sapiens ENSP00000434995 89.8824 78.3529 electrophorus_electricus ENSEEEP00000032167 86.2302 75.1693 ENSG00000172409 homo_sapiens ENSP00000434995 89.8824 79.7647 oncorhynchus_kisutch ENSOKIP00005026110 85.8427 76.1798 ENSG00000172409 homo_sapiens ENSP00000434995 88.7059 77.4118 oncorhynchus_kisutch ENSOKIP00005057778 84.34 73.6018 ENSG00000172409 homo_sapiens ENSP00000434995 89.6471 79.5294 oncorhynchus_mykiss ENSOMYP00000048841 85.618 75.9551 ENSG00000172409 homo_sapiens ENSP00000434995 88 77.6471 oncorhynchus_mykiss ENSOMYP00000080923 84.8073 74.8299 ENSG00000172409 homo_sapiens ENSP00000434995 88.4706 77.6471 salmo_salar ENSSSAP00000058864 80.1706 70.3625 ENSG00000172409 homo_sapiens ENSP00000434995 89.6471 79.5294 salmo_salar ENSSSAP00000137226 83.5526 74.1228 ENSG00000172409 homo_sapiens ENSP00000434995 89.6471 79.2941 salmo_trutta ENSSTUP00000068588 85.618 75.7303 ENSG00000172409 homo_sapiens ENSP00000434995 88.4706 77.6471 salmo_trutta ENSSTUP00000038468 85.2608 74.8299 ENSG00000172409 homo_sapiens ENSP00000434995 89.1765 78.8235 gadus_morhua ENSGMOP00000020794 86.5297 76.484 ENSG00000172409 homo_sapiens ENSP00000434995 88 76 fundulus_heteroclitus ENSFHEP00000029829 84.8073 73.2426 ENSG00000172409 homo_sapiens ENSP00000434995 88.2353 76.2353 poecilia_reticulata ENSPREP00000026331 85.034 73.4694 ENSG00000172409 homo_sapiens ENSP00000434995 88.4706 76.2353 xiphophorus_maculatus ENSXMAP00000009805 85.2608 73.4694 ENSG00000172409 homo_sapiens ENSP00000434995 88 75.5294 oryzias_latipes ENSORLP00000004544 84.8073 72.7891 ENSG00000172409 homo_sapiens ENSP00000434995 88.7059 76.7059 cyclopterus_lumpus ENSCLMP00005020129 85.4875 73.9229 ENSG00000172409 homo_sapiens ENSP00000434995 88.9412 75.7647 oreochromis_niloticus ENSONIP00000006399 85.7143 73.0159 ENSG00000172409 homo_sapiens ENSP00000434995 88.7059 76 haplochromis_burtoni ENSHBUP00000027302 85.4875 73.2426 ENSG00000172409 homo_sapiens ENSP00000434995 88.9412 76 astatotilapia_calliptera ENSACLP00000019957 85.7143 73.2426 ENSG00000172409 homo_sapiens ENSP00000434995 88.7059 77.6471 sparus_aurata ENSSAUP00010018952 84.9099 74.3243 ENSG00000172409 homo_sapiens ENSP00000434995 88.7059 76.9412 lates_calcarifer ENSLCAP00010039704 85.4875 74.1497 ENSG00000172409 homo_sapiens ENSP00000434995 86.3529 76.9412 xenopus_tropicalis ENSXETP00000015427 83.9817 74.8284 ENSG00000172409 homo_sapiens ENSP00000434995 97.8824 94.3529 chrysemys_picta_bellii ENSCPBP00000023588 97.8824 94.3529 ENSG00000172409 homo_sapiens ENSP00000434995 97.6471 93.6471 sphenodon_punctatus ENSSPUP00000021912 97.6471 93.6471 ENSG00000172409 homo_sapiens ENSP00000434995 97.6471 94.3529 crocodylus_porosus ENSCPRP00005012508 97.6471 94.3529 ENSG00000172409 homo_sapiens ENSP00000434995 97.6471 93.6471 laticauda_laticaudata ENSLLTP00000021999 97.6471 93.6471 ENSG00000172409 homo_sapiens ENSP00000434995 97.6471 93.6471 notechis_scutatus ENSNSUP00000023499 97.6471 93.6471 ENSG00000172409 homo_sapiens ENSP00000434995 97.6471 93.6471 pseudonaja_textilis ENSPTXP00000013687 97.6471 93.6471 ENSG00000172409 homo_sapiens ENSP00000434995 97.4118 93.6471 anas_platyrhynchos_platyrhynchos ENSAPLP00000021433 97.4118 93.6471 ENSG00000172409 homo_sapiens ENSP00000434995 97.4118 93.4118 gallus_gallus ENSGALP00010039366 97.4118 93.4118 ENSG00000172409 homo_sapiens ENSP00000434995 97.4118 93.4118 meleagris_gallopavo ENSMGAP00000009953 97.4118 93.4118 ENSG00000172409 homo_sapiens ENSP00000434995 96.9412 92.7059 serinus_canaria ENSSCAP00000013454 96.9412 92.7059 ENSG00000172409 homo_sapiens ENSP00000434995 97.1765 92.7059 parus_major ENSPMJP00000007907 80.3502 76.6537 ENSG00000172409 homo_sapiens ENSP00000434995 97.1765 94.3529 anolis_carolinensis ENSACAP00000006983 97.1765 94.3529 ENSG00000172409 homo_sapiens ENSP00000434995 88.9412 76 neolamprologus_brichardi ENSNBRP00000006632 85.7143 73.2426 ENSG00000172409 homo_sapiens ENSP00000434995 97.6471 93.6471 naja_naja ENSNNAP00000001534 97.6471 93.6471 ENSG00000172409 homo_sapiens ENSP00000434995 97.4118 94.3529 podarcis_muralis ENSPMRP00000001811 97.4118 94.3529 ENSG00000172409 homo_sapiens ENSP00000434995 55.5294 54.3529 geospiza_fortis ENSGFOP00000015527 55.792 54.6099 ENSG00000172409 homo_sapiens ENSP00000434995 96.9412 92.7059 taeniopygia_guttata ENSTGUP00000007203 96.9412 92.7059 ENSG00000172409 homo_sapiens ENSP00000434995 92.9412 83.0588 erpetoichthys_calabaricus ENSECRP00000014607 92.723 82.8639 ENSG00000172409 homo_sapiens ENSP00000434995 88.4706 75.7647 kryptolebias_marmoratus ENSKMAP00000016065 85.2608 73.0159 ENSG00000172409 homo_sapiens ENSP00000434995 97.4118 94.5882 salvator_merianae ENSSMRP00000001082 97.4118 94.5882 ENSG00000172409 homo_sapiens ENSP00000434995 88 76.2353 oryzias_javanicus ENSOJAP00000026631 75.1004 65.0602 ENSG00000172409 homo_sapiens ENSP00000434995 88.7059 76 amphilophus_citrinellus ENSACIP00000008045 84.9099 72.7477 ENSG00000172409 homo_sapiens ENSP00000434995 89.1765 76.7059 dicentrarchus_labrax ENSDLAP00005034607 85.3604 73.4234 ENSG00000172409 homo_sapiens ENSP00000434995 88.7059 76.7059 amphiprion_percula ENSAPEP00000017024 85.4875 73.9229 ENSG00000172409 homo_sapiens ENSP00000434995 88 75.2941 oryzias_sinensis ENSOSIP00000028442 84.8073 72.5624 ENSG00000172409 homo_sapiens ENSP00000434995 90.5882 87.2941 pelodiscus_sinensis ENSPSIP00000005885 98.2143 94.6429 ENSG00000172409 homo_sapiens ENSP00000434995 97.8824 94.1176 gopherus_evgoodei ENSGEVP00005011393 97.8824 94.1176 ENSG00000172409 homo_sapiens ENSP00000434995 89.8824 86.8235 chelonoidis_abingdonii ENSCABP00000027896 99.2208 95.8442 ENSG00000172409 homo_sapiens ENSP00000434995 89.1765 77.4118 seriola_dumerili ENSSDUP00000019930 85.941 74.6032 ENSG00000172409 homo_sapiens ENSP00000434995 88.9412 77.1765 cottoperca_gobio ENSCGOP00000016072 85.7143 74.3764 ENSG00000172409 homo_sapiens ENSP00000434995 75.0588 72.7059 struthio_camelus_australis ENSSCUP00000004722 73.8426 71.5278 ENSG00000172409 homo_sapiens ENSP00000434995 97.4118 93.4118 anser_brachyrhynchus ENSABRP00000006617 97.4118 93.4118 ENSG00000172409 homo_sapiens ENSP00000434995 88.9412 77.1765 gasterosteus_aculeatus ENSGACP00000023566 85.7143 74.3764 ENSG00000172409 homo_sapiens ENSP00000434995 87.2941 75.2941 cynoglossus_semilaevis ENSCSEP00000013345 84.127 72.5624 ENSG00000172409 homo_sapiens ENSP00000434995 88.4706 76 poecilia_formosa ENSPFOP00000008141 85.2608 73.2426 ENSG00000172409 homo_sapiens ENSP00000434995 89.6471 79.0588 myripristis_murdjan ENSMMDP00005018430 86.9863 76.7123 ENSG00000172409 homo_sapiens ENSP00000434995 88.7059 77.4118 sander_lucioperca ENSSLUP00000000975 85.4875 74.6032 ENSG00000172409 homo_sapiens ENSP00000434995 97.1765 92.2353 strigops_habroptila ENSSHBP00005002178 97.1765 92.2353 ENSG00000172409 homo_sapiens ENSP00000434995 88.7059 76.7059 amphiprion_ocellaris ENSAOCP00000006967 85.4875 73.9229 ENSG00000172409 homo_sapiens ENSP00000434995 97.8824 94.3529 terrapene_carolina_triunguis ENSTMTP00000030562 97.8824 94.3529 ENSG00000172409 homo_sapiens ENSP00000434995 88.4706 77.6471 hucho_hucho ENSHHUP00000016981 84.8758 74.4921 ENSG00000172409 homo_sapiens ENSP00000434995 89.6471 79.5294 hucho_hucho ENSHHUP00000048076 85.618 75.9551 ENSG00000172409 homo_sapiens ENSP00000434995 88.4706 76.7059 betta_splendens ENSBSLP00000018025 85.2608 73.9229 ENSG00000172409 homo_sapiens ENSP00000434995 89.4118 79.2941 pygocentrus_nattereri ENSPNAP00000036000 85.3933 75.7303 ENSG00000172409 homo_sapiens ENSP00000434995 89.1765 76.9412 anabas_testudineus ENSATEP00000017788 85.941 74.1497 ENSG00000172409 homo_sapiens ENSP00000434995 80.4706 62.8235 ciona_savignyi ENSCSAVP00000005762 80.4706 62.8235 ENSG00000172409 homo_sapiens ENSP00000434995 49.1765 25.6471 saccharomyces_cerevisiae YOR250C 46.9663 24.4944 ENSG00000172409 homo_sapiens ENSP00000434995 88.9412 77.1765 seriola_lalandi_dorsalis ENSSLDP00000001098 85.7143 74.3764 ENSG00000172409 homo_sapiens ENSP00000434995 87.5294 75.2941 labrus_bergylta ENSLBEP00000013286 83.5955 71.9101 ENSG00000172409 homo_sapiens ENSP00000434995 88.7059 76 pundamilia_nyererei ENSPNYP00000022890 84.9099 72.7477 ENSG00000172409 homo_sapiens ENSP00000434995 88.9412 76.9412 mastacembelus_armatus ENSMAMP00000003136 85.7143 74.1497 ENSG00000172409 homo_sapiens ENSP00000434995 88.7059 76.2353 stegastes_partitus ENSSPAP00000021285 85.4875 73.4694 ENSG00000172409 homo_sapiens ENSP00000434995 87.7647 76.7059 oncorhynchus_tshawytscha ENSOTSP00005025445 83.6323 73.0942 ENSG00000172409 homo_sapiens ENSP00000434995 89.6471 79.5294 oncorhynchus_tshawytscha ENSOTSP00005044990 85.618 75.9551 ENSG00000172409 homo_sapiens ENSP00000434995 88.4706 76.7059 acanthochromis_polyacanthus ENSAPOP00000006386 85.2608 73.9229 ENSG00000172409 homo_sapiens ENSP00000434995 97.6471 93.4118 aquila_chrysaetos_chrysaetos ENSACCP00020015081 97.6471 93.4118 ENSG00000172409 homo_sapiens ENSP00000434995 88.9412 75.5294 nothobranchius_furzeri ENSNFUP00015007423 85.7143 72.7891 ENSG00000172409 homo_sapiens ENSP00000434995 89.4118 76.9412 cyprinodon_variegatus ENSCVAP00000017051 86.1678 74.1497 ENSG00000172409 homo_sapiens ENSP00000434995 89.6471 78.5882 denticeps_clupeoides ENSDCDP00000017727 84.8552 74.3875 ENSG00000172409 homo_sapiens ENSP00000434995 89.4118 76.9412 larimichthys_crocea ENSLCRP00005051477 86.1678 74.1497 ENSG00000172409 homo_sapiens ENSP00000434995 88.4706 76.9412 takifugu_rubripes ENSTRUP00000031904 86.2385 75 ENSG00000172409 homo_sapiens ENSP00000434995 97.1765 92.7059 ficedula_albicollis ENSFALP00000011636 97.1765 92.7059 ENSG00000172409 homo_sapiens ENSP00000434995 88.9412 78.1176 hippocampus_comes ENSHCOP00000007943 85.7143 75.2834 ENSG00000172409 homo_sapiens ENSP00000434995 90.1176 78.3529 cyprinus_carpio_carpio ENSCCRP00000010966 86.0674 74.8315 ENSG00000172409 homo_sapiens ENSP00000434995 90.1176 78.8235 cyprinus_carpio_carpio ENSCCRP00000032389 86.0674 75.2809 ENSG00000172409 homo_sapiens ENSP00000434995 97.4118 93.4118 coturnix_japonica ENSCJPP00005022040 97.4118 93.4118 ENSG00000172409 homo_sapiens ENSP00000434995 88.4706 76 poecilia_latipinna ENSPLAP00000030885 85.2608 73.2426 ENSG00000172409 homo_sapiens ENSP00000434995 89.6471 78.5882 sinocyclocheilus_grahami ENSSGRP00000089605 85.618 75.0562 ENSG00000172409 homo_sapiens ENSP00000434995 89.8824 78.5882 sinocyclocheilus_grahami ENSSGRP00000097247 85.8427 75.0562 ENSG00000172409 homo_sapiens ENSP00000434995 88.9412 76 maylandia_zebra ENSMZEP00005003690 85.7143 73.2426 ENSG00000172409 homo_sapiens ENSP00000434995 88.4706 76.4706 tetraodon_nigroviridis ENSTNIP00000016107 86.2385 74.5413 ENSG00000172409 homo_sapiens ENSP00000434995 89.6471 78.3529 paramormyrops_kingsleyae ENSPKIP00000024445 84.8552 74.1648 ENSG00000172409 homo_sapiens ENSP00000434995 90.3529 78.8235 scleropages_formosus ENSSFOP00015000845 85.3333 74.4444 ENSG00000172409 homo_sapiens ENSP00000434995 85.6471 77.6471 leptobrachium_leishanense ENSLLEP00000023997 82.167 74.4921 ENSG00000172409 homo_sapiens ENSP00000434995 88.2353 76 scophthalmus_maximus ENSSMAP00000031695 84.0807 72.4215 ENSG00000172409 homo_sapiens ENSP00000434995 88 76.4706 oryzias_melastigma ENSOMEP00000034586 84.8073 73.6961
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000214 part_of tRNA-intron endonuclease complex 1 IDA Homo_sapiens(9606) Component GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005524 enables ATP binding 1 TAS Homo_sapiens(9606) Function GO:0005634 is_active_in nucleus 2 IBA,IDA Homo_sapiens(9606) Component GO:0005654 located_in nucleoplasm 2 IDA,TAS Homo_sapiens(9606) Component GO:0005829 located_in cytosol 1 IDA Homo_sapiens(9606) Component GO:0005849 part_of mRNA cleavage factor complex 1 IEA Homo_sapiens(9606) Component GO:0006378 involved_in mRNA polyadenylation 1 IBA Homo_sapiens(9606) Process GO:0006388 involved_in tRNA splicing, via endonucleolytic cleavage and ligation 3 IBA,IDA,IMP Homo_sapiens(9606) Process GO:0016310 involved_in phosphorylation 1 IEA Homo_sapiens(9606) Process GO:0021695 involved_in cerebellar cortex development 1 IMP Homo_sapiens(9606) Process GO:0031124 involved_in mRNA 3-end processing 1 TAS Homo_sapiens(9606) Process GO:0046404 enables ATP-dependent polydeoxyribonucleotide 5-hydroxyl-kinase activity 1 IDA Homo_sapiens(9606) Function GO:0051731 enables polynucleotide 5-hydroxyl-kinase activity 1 IBA Homo_sapiens(9606) Function GO:0051736 enables ATP-dependent polyribonucleotide 5-hydroxyl-kinase activity 2 IDA,IMP Homo_sapiens(9606) Function GO:0070922 involved_in RISC complex assembly 1 IDA Homo_sapiens(9606) Process GO:0098795 involved_in global gene silencing by mRNA cleavage 1 IMP Homo_sapiens(9606) Process
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