RBPWorld - a comprehensive database of RNA Binding Proteins

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Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	SARS-COV-2
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzymeE3 ligase
Localizations	Stress granucle
BulkPerturb-seq

Description

Ensembl ID	ENSG00000172354	Gene ID	2783	Accession	4398
Symbol	GNB2	Alias	SSS4;HG2C1;SSS4;NEDHYDF	Full Name	G protein subunit beta 2
Status	Confidence	Length	5608 bases	Strand	Plus strand
Position	7 : 100673567 - 100679174	RNA binding domain	N.A.
Summary	Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5' UTR. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
GNB2-210	ENST00000451587	887	251aa	ENSP00000399904
GNB2-201	ENST00000303210	1664	340aa	ENSP00000305260
GNB2-209	ENST00000436220	1479	296aa	ENSP00000401873
GNB2-206	ENST00000424361	1478	296aa	ENSP00000389391
GNB2-205	ENST00000419828	1285	240aa	ENSP00000390543
GNB2-207	ENST00000427895	1146	240aa	ENSP00000400286
GNB2-203	ENST00000393926	1641	340aa	ENSP00000377503
GNB2-208	ENST00000431068	910	232aa	ENSP00000390077
GNB2-204	ENST00000412215	545	152aa	ENSP00000413219
GNB2-202	ENST00000393924	1524	340aa	ENSP00000377501
GNB2-213	ENST00000480159	899	No protein	-
GNB2-211	ENST00000469287	1702	No protein	-
GNB2-212	ENST00000470354	902	No protein	-

Gene Model

Click here to download ENSG00000172354's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000172354's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0003924	enables GTPase activity	1	TAS	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005615	located_in extracellular space	1	HDA	Homo_sapiens(9606)	Component
GO:0005737	is_active_in cytoplasm	1	IBA	Homo_sapiens(9606)	Component
GO:0005765	located_in lysosomal membrane	1	HDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	TAS	Homo_sapiens(9606)	Component
GO:0005834	part_of heterotrimeric G-protein complex	1	IBA	Homo_sapiens(9606)	Component
GO:0005886	located_in plasma membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0005925	located_in focal adhesion	1	HDA	Homo_sapiens(9606)	Component
GO:0007186	involved_in G protein-coupled receptor signaling pathway	1	IBA	Homo_sapiens(9606)	Process
GO:0016020	located_in membrane	1	HDA	Homo_sapiens(9606)	Component
GO:0030159	enables signaling receptor complex adaptor activity	1	IBA	Homo_sapiens(9606)	Function
GO:0031982	located_in vesicle	1	HDA	Homo_sapiens(9606)	Component
GO:0044877	enables protein-containing complex binding	1	IDA	Homo_sapiens(9606)	Function
GO:0048471	located_in perinuclear region of cytoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0051020	enables GTPase binding	1	IPI	Homo_sapiens(9606)	Function
GO:0070062	located_in extracellular exosome	1	HDA	Homo_sapiens(9606)	Component
GO:1901379	involved_in regulation of potassium ion transmembrane transport	1	IMP	Homo_sapiens(9606)	Process

Expression