RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Kinase
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000172315	Gene ID	112858	Accession	16197
Symbol	TP53RK	Alias	PRPK;BUD32;TPRKB;GAMOS4;Nori-2;Nori-2p;dJ101A2;C20orf64	Full Name	TP53 regulating kinase
Status	Confidence	Length	5080 bases	Strand	Minus strand
Position	20 : 46684365 - 46689444	RNA binding domain	RIO1
Summary	Enables p53 binding activity and protein serine/threonine kinase activity. Involved in protein phosphorylation. Located in cytoplasm and nucleus. Part of EKC/KEOPS complex. Implicated in Galloway-Mowat syndrome 4. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000361186	RIO1	PF01163	4.2e-07	1

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
TP53RK-202	ENST00000372114	3180	253aa	ENSP00000361186
TP53RK-201	ENST00000372102	2012	121aa	ENSP00000361174

Gene Model

Click here to download ENSG00000172315's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
22976	Body Height	9.2180000E-005	-

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000172315's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000408	part_of EKC/KEOPS complex	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0002039	enables p53 binding	1	IDA	Homo_sapiens(9606)	Function
GO:0004674	enables protein serine/threonine kinase activity	3	IBA,IDA,TAS	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005524	enables ATP binding	1	IEA	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	TAS	Homo_sapiens(9606)	Component
GO:0005737	located_in cytoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0005829	is_active_in cytosol	1	IBA	Homo_sapiens(9606)	Component
GO:0006468	involved_in protein phosphorylation	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0008033	involved_in tRNA processing	1	IEA	Homo_sapiens(9606)	Process
GO:0016787	enables hydrolase activity	1	IEA	Homo_sapiens(9606)	Function
GO:0070525	involved_in tRNA threonylcarbamoyladenosine metabolic process	1	IBA	Homo_sapiens(9606)	Process
GO:0106310	enables protein serine kinase activity	1	IEA	Homo_sapiens(9606)	Function
GO:1901796	involved_in regulation of signal transduction by p53 class mediator	1	TAS	Homo_sapiens(9606)	Process

Expression