Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs diverse
Moonlighting functions N.A.
Localizations NucleoliNucleoli rim
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000171824 Gene ID 5394 Accession 9138
Symbol EXOSC10 Alias p2;p3;p4;RRP6;PMSCL;Rrp6p;PM-Scl;PMSCL2;PM/Scl-100 Full Name exosome component 10
Status Confidence Length 33252 bases Strand Minus strand
Position 1 : 11066618 - 11099869 RNA binding domain DNA_pol_A_exo1 , PMC2NT , HRDC
Summary Enables 3'-5'-exoribonuclease activity. Involved in several processes, including RNA catabolic process; maturation of 5.8S rRNA; and negative regulation of telomere maintenance via telomerase. Located in cytosol; nuclear lumen; and transcriptionally active chromatin. Part of nuclear exosome (RNase complex). [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000307307 HRDC PF00570 4.5e-13 1
ENSP00000307307 PMC2NT PF08066 1.1e-21 2
ENSP00000307307 DNA_pol_A_exo1 PF01612 1.3e-49 3
ENSP00000366135 HRDC PF00570 4.7e-13 1
ENSP00000366135 PMC2NT PF08066 1.1e-21 2
ENSP00000366135 DNA_pol_A_exo1 PF01612 1.3e-49 3
ENSP00000465008 PMC2NT PF08066 1.3e-18 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
36793534 RNA Dysmetabolism and Repeat-Associated Non-AUG Translation in Frontotemporal Lobar Degeneration/Amyotrophic Lateral Sclerosis due to C9orf72 Hexanucleotide Repeat Expansion. Kohji Mori 2023-01-16 JMA journal
34516797 Nucleolar maturation of the human small subunit processome. Sameer Singh 2021-09-10 Science (New York, N.Y.)
36912080 The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing. Yingxiao Chen 2023-05-08 Nucleic acids research
32830871 The RNA exosome complex degrades expanded hexanucleotide repeat RNA in C9orf72 FTLD/ALS. Yuya Kawabe 2020-10-01 The EMBO journal
27402899 Purification and analysis of endogenous human RNA exosome complexes. Michal Domanski 2016-09-01 RNA (New York, N.Y.)
31053471 PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy. Xinyi Tu 2019-06-20 Molecular cell

Transcripts

Name Transcript ID bp Protein Translation ID
EXOSC10-201 ENST00000304457 2721 860aa ENSP00000307307
EXOSC10-202 ENST00000376936 2796 885aa ENSP00000366135
EXOSC10-207 ENST00000474216 2007 No protein -
EXOSC10-210 ENST00000490565 421 No protein -
EXOSC10-204 ENST00000469634 2361 No protein -
EXOSC10-208 ENST00000478271 608 No protein -
EXOSC10-205 ENST00000470611 401 No protein -
EXOSC10-211 ENST00000498576 486 No protein -
EXOSC10-206 ENST00000472078 412 No protein -
EXOSC10-209 ENST00000485606 459 No protein -
EXOSC10-203 ENST00000460196 622 124aa ENSP00000465008

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
19545Pulse Wave Analysis9.874e-007-
19550Pulse Wave Analysis3.329e-007-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000171824homo_sapiensENSP0000041505631.468516.6084homo_sapiensENSP0000036613520.33910.7345

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000171824homo_sapiensENSP0000036613598.418197.6271nomascus_leucogenysENSNLEP0000001165097.536496.7525
ENSG00000171824homo_sapiensENSP0000036613510099.774pan_paniscusENSPPAP0000003084599.438299.2135
ENSG00000171824homo_sapiensENSP0000036613599.32298.4181pongo_abeliiENSPPYP0000000219196.699795.8196
ENSG00000171824homo_sapiensENSP0000036613595.593295.1412pan_troglodytesENSPTRP0000006227297.353396.893
ENSG00000171824homo_sapiensENSP0000036613597.627196.9492gorilla_gorillaENSGGOP0000003152797.297396.6216
ENSG00000171824homo_sapiensENSP0000036613586.440776.7232ornithorhynchus_anatinusENSOANP0000003505183.606674.2076
ENSG00000171824homo_sapiensENSP0000036613587.570677.9661sarcophilus_harrisiiENSSHAP0000001593285.540876.1589
ENSG00000171824homo_sapiensENSP0000036613555.254249.1525notamacropus_eugeniiENSMEUP0000000643055.631449.4881
ENSG00000171824homo_sapiensENSP0000036613587.457682.7119choloepus_hoffmanniENSCHOP0000001127188.457183.6571
ENSG00000171824homo_sapiensENSP0000036613594.011388.5876dasypus_novemcinctusENSDNOP0000000877994.760889.2938
ENSG00000171824homo_sapiensENSP0000036613569.717564.8588erinaceus_europaeusENSEEUP0000000105875.798570.516
ENSG00000171824homo_sapiensENSP0000036613586.779781.5819echinops_telfairiENSETEP0000000067590.140884.7418
ENSG00000171824homo_sapiensENSP0000036613594.689392.6554callithrix_jacchusENSCJAP0000000423397.441995.3488
ENSG00000171824homo_sapiensENSP0000036613598.98398.0791cercocebus_atysENSCATP0000003193099.09598.19
ENSG00000171824homo_sapiensENSP0000036613592.316490.8475macaca_fascicularisENSMFAP0000003952089.681788.2547
ENSG00000171824homo_sapiensENSP0000036613594.350392.7684macaca_mulattaENSMMUP0000007413989.978488.4698
ENSG00000171824homo_sapiensENSP0000036613598.757197.9661macaca_nemestrinaENSMNEP0000002470798.868898.0769
ENSG00000171824homo_sapiensENSP0000036613598.870197.9661papio_anubisENSPANP0000000622096.365695.4846
ENSG00000171824homo_sapiensENSP0000036613598.98398.0791mandrillus_leucophaeusENSMLEP0000000597899.09598.19
ENSG00000171824homo_sapiensENSP0000036613594.237389.8305tursiops_truncatusENSTTRP0000000124094.130989.7291
ENSG00000171824homo_sapiensENSP0000036613585.649780.791vulpes_vulpesENSVVUP0000003795194.39689.0411
ENSG00000171824homo_sapiensENSP0000036613592.203487.0057mus_spretusMGP_SPRETEiJ_P006836491.995586.8095
ENSG00000171824homo_sapiensENSP0000036613593.785388.4746equus_asinusENSEASP0000502793685.56780.7216
ENSG00000171824homo_sapiensENSP0000036613589.717585.4237capra_hircusENSCHIP0000002185694.075889.5735
ENSG00000171824homo_sapiensENSP0000036613594.124390.7345loxodonta_africanaENSLAFP0000001416493.912190.5299
ENSG00000171824homo_sapiensENSP0000036613594.463390.3955panthera_leoENSPLOP0000001031694.250390.1917
ENSG00000171824homo_sapiensENSP0000036613594.463389.8305ailuropoda_melanoleucaENSAMEP0000001009889.989285.5759
ENSG00000171824homo_sapiensENSP0000036613594.576389.9435bos_indicus_hybridENSBIXP0000503840694.36389.7407
ENSG00000171824homo_sapiensENSP0000036613594.237388.7006oryctolagus_cuniculusENSOCUP0000004907389.293484.0471
ENSG00000171824homo_sapiensENSP0000036613593.785388.4746equus_caballusENSECAP0000007953482.669377.988
ENSG00000171824homo_sapiensENSP0000036613594.350389.7175canis_lupus_familiarisENSCAFP0084500384591.960487.4449
ENSG00000171824homo_sapiensENSP0000036613593.672389.6045panthera_pardusENSPPRP0000000307594.419190.3189
ENSG00000171824homo_sapiensENSP0000036613585.762781.4689marmota_marmota_marmotaENSMMMP0000001903094.87590.125
ENSG00000171824homo_sapiensENSP0000036613591.638486.7797balaenoptera_musculusENSBMSP0001000916191.021386.1953
ENSG00000171824homo_sapiensENSP0000036613593.898388.3616cavia_porcellusENSCPOP0000003164492.230986.7924
ENSG00000171824homo_sapiensENSP0000036613594.463390.5085felis_catusENSFCAP0000000004694.250390.3044
ENSG00000171824homo_sapiensENSP0000036613590.734586.8927ursus_americanusENSUAMP0000001814392.618288.6967
ENSG00000171824homo_sapiensENSP0000036613589.039679.096monodelphis_domesticaENSMODP0000001400388.738778.8288
ENSG00000171824homo_sapiensENSP0000036613594.124389.4915bison_bison_bisonENSBBBP0000002608594.444489.7959
ENSG00000171824homo_sapiensENSP0000036613593.785389.6045monodon_monocerosENSMMNP0001501003593.573889.4025
ENSG00000171824homo_sapiensENSP0000036613590.960486.4407sus_scrofaENSSSCP0000007732087.690683.3333
ENSG00000171824homo_sapiensENSP0000036613595.141291.7514microcebus_murinusENSMICP0000002616495.141291.7514
ENSG00000171824homo_sapiensENSP0000036613592.090487.4576octodon_degusENSODEP0000001802189.757785.2423
ENSG00000171824homo_sapiensENSP0000036613592.994387.5706jaculus_jaculusENSJJAP0000001009092.889487.4718
ENSG00000171824homo_sapiensENSP0000036613594.463390.0565ovis_aries_rambouilletENSOARP0002001820694.250389.8534
ENSG00000171824homo_sapiensENSP0000036613591.525486.5537ursus_maritimusENSUMAP0000003290992.571487.5429
ENSG00000171824homo_sapiensENSP0000036613593.333388.0226ochotona_princepsENSOPRP0000001104793.333388.0226
ENSG00000171824homo_sapiensENSP0000036613590.395586.3277delphinapterus_leucasENSDLEP0000000892591.012586.917
ENSG00000171824homo_sapiensENSP0000036613590.508586.4407physeter_catodonENSPCTP0000500409476.650773.2057
ENSG00000171824homo_sapiensENSP0000036613592.203487.1186mus_caroliMGP_CAROLIEiJ_P006578791.995586.9222
ENSG00000171824homo_sapiensENSP0000036613592.429487.2316mus_musculusENSMUSP0000001740892.22187.035
ENSG00000171824homo_sapiensENSP0000036613588.135683.1638dipodomys_ordiiENSDORP0000000352091.764786.5882
ENSG00000171824homo_sapiensENSP0000036613594.237389.6045mustela_putorius_furoENSMPUP0000001633091.850287.3348
ENSG00000171824homo_sapiensENSP0000036613592.768490.7345aotus_nancymaaeENSANAP0000002676197.854695.7092
ENSG00000171824homo_sapiensENSP0000036613589.265587.5706saimiri_boliviensis_boliviensisENSSBOP0000000772597.651495.7973
ENSG00000171824homo_sapiensENSP0000036613564.293862.5989vicugna_pacosENSVPAP0000000429864.293862.5989
ENSG00000171824homo_sapiensENSP0000036613598.644197.6271chlorocebus_sabaeusENSCSAP0000001721898.755797.7376
ENSG00000171824homo_sapiensENSP0000036613564.406861.1299tupaia_belangeriENSTBEP0000001521264.406861.1299
ENSG00000171824homo_sapiensENSP0000036613566.553764.0678mesocricetus_auratusENSMAUP0000002156795.307491.7476
ENSG00000171824homo_sapiensENSP0000036613593.898389.8305phocoena_sinusENSPSNP0000001363488.87785.0267
ENSG00000171824homo_sapiensENSP0000036613594.463390.5085camelus_dromedariusENSCDRP0000502372894.038290.1012
ENSG00000171824homo_sapiensENSP0000036613591.073486.6667carlito_syrichtaENSTSYP0000003369293.503588.9791
ENSG00000171824homo_sapiensENSP0000036613588.135684.8588panthera_tigris_altaicaENSPTIP0000001281292.307788.8757
ENSG00000171824homo_sapiensENSP0000036613592.429487.2316rattus_norvegicusENSRNOP0000001462992.429487.2316
ENSG00000171824homo_sapiensENSP0000036613589.378585.9887prolemur_simusENSPSMP0000003566889.378585.9887
ENSG00000171824homo_sapiensENSP0000036613566.892764.0678microtus_ochrogasterENSMOCP0000001811995.792991.7476
ENSG00000171824homo_sapiensENSP0000036613562.372954.5763sorex_araneusENSSARP0000001189475.720266.2551
ENSG00000171824homo_sapiensENSP0000036613593.559388.5876peromyscus_maniculatus_bairdiiENSPEMP0000000530693.348488.3878
ENSG00000171824homo_sapiensENSP0000036613593.898389.4915bos_mutusENSBMUP0000000125494.431890
ENSG00000171824homo_sapiensENSP0000036613592.429487.1186mus_spicilegusENSMSIP0000001372792.22186.9222
ENSG00000171824homo_sapiensENSP0000036613593.220388.5876cricetulus_griseus_chok1gshdENSCGRP0000101885793.220388.5876
ENSG00000171824homo_sapiensENSP0000036613594.124390.1695pteropus_vampyrusENSPVAP0000001393394.659190.6818
ENSG00000171824homo_sapiensENSP0000036613594.463389.6045myotis_lucifugusENSMLUP0000000390294.250389.4025
ENSG00000171824homo_sapiensENSP0000036613589.830578.7571vombatus_ursinusENSVURP0001003143389.62878.5795
ENSG00000171824homo_sapiensENSP0000036613594.915390.7345rhinolophus_ferrumequinumENSRFEP0001002285494.38290.2247
ENSG00000171824homo_sapiensENSP0000036613588.474683.1638neovison_visonENSNVIP0000000998171.506967.2146
ENSG00000171824homo_sapiensENSP0000036613575.028372.2034bos_taurusENSBTAP0000004864094.586991.0256
ENSG00000171824homo_sapiensENSP0000036613593.785388.7006heterocephalus_glaber_femaleENSHGLP0000001668993.997788.9015
ENSG00000171824homo_sapiensENSP0000036613588.135687.0057rhinopithecus_bietiENSRBIP0000003194597.014995.7711
ENSG00000171824homo_sapiensENSP0000036613594.350389.7175canis_lupus_dingoENSCAFP0002000295491.960487.4449
ENSG00000171824homo_sapiensENSP0000036613594.350389.4915sciurus_vulgarisENSSVLP0000500707894.243889.3905
ENSG00000171824homo_sapiensENSP0000036613584.067874.1243phascolarctos_cinereusENSPCIP0000000966485.125975.0572
ENSG00000171824homo_sapiensENSP0000036613574.124371.7514procavia_capensisENSPCAP0000000154883.248780.5838
ENSG00000171824homo_sapiensENSP0000036613594.011389.2655nannospalax_galiliENSNGAP0000002608393.905289.1648
ENSG00000171824homo_sapiensENSP0000036613594.237389.8305bos_grunniensENSBGRP0000001847994.557890.1361
ENSG00000171824homo_sapiensENSP0000036613593.107388.1356chinchilla_lanigeraENSCLAP0000000752493.002388.0361
ENSG00000171824homo_sapiensENSP0000036613593.672389.2655cervus_hanglu_yarkandensisENSCHYP0000003699394.634790.1826
ENSG00000171824homo_sapiensENSP0000036613594.463390.5085catagonus_wagneriENSCWAP0000000773594.356790.4063
ENSG00000171824homo_sapiensENSP0000036613594.689389.9435ictidomys_tridecemlineatusENSSTOP0000002784594.582489.842
ENSG00000171824homo_sapiensENSP0000036613588.926683.6158otolemur_garnettiiENSOGAP0000001224088.72683.4273
ENSG00000171824homo_sapiensENSP0000036613591.864489.9435cebus_imitatorENSCCAP0000001109494.644992.6659
ENSG00000171824homo_sapiensENSP0000036613594.689390.0565urocitellus_parryiiENSUPAP0001000418994.582489.9549
ENSG00000171824homo_sapiensENSP0000036613594.689389.7175moschus_moschiferusENSMMSP0000002491287.932883.3158
ENSG00000171824homo_sapiensENSP0000036613598.418197.4011rhinopithecus_roxellanaENSRROP0000002599398.529497.5113
ENSG00000171824homo_sapiensENSP0000036613592.881487.5706mus_pahariMGP_PahariEiJ_P008089592.671987.3732
ENSG00000171824homo_sapiensENSP0000036613595.141291.1864propithecus_coquereliENSPCOP0000000559195.899891.9134
ENSG00000171824homo_sapiensENSP0000036613547.909628.5876caenorhabditis_elegansC14A4.4a.148.401828.8813
ENSG00000171824homo_sapiensENSP0000036613553.107334.9153drosophila_melanogasterFBpp031191152.222234.3333
ENSG00000171824homo_sapiensENSP0000036613520.56514.4633ciona_intestinalisENSCINP0000003482069.731849.0421
ENSG00000171824homo_sapiensENSP0000036613525.197719.774ciona_intestinalisENSCINP0000000485276.369959.9315
ENSG00000171824homo_sapiensENSP0000036613513.22039.60452ciona_intestinalisENSCINP0000003323160.309343.8144
ENSG00000171824homo_sapiensENSP0000036613519.54815.8192petromyzon_marinusENSPMAP0000000709980.841165.4206
ENSG00000171824homo_sapiensENSP0000036613514.689312.0904petromyzon_marinusENSPMAP0000000060181.2566.875
ENSG00000171824homo_sapiensENSP0000036613519.54815.5932petromyzon_marinusENSPMAP0000000709780.465164.186
ENSG00000171824homo_sapiensENSP0000036613519.43515.4802petromyzon_marinusENSPMAP0000001066180.373864.0187
ENSG00000171824homo_sapiensENSP0000036613522.485917.9661petromyzon_marinusENSPMAP0000000763377.131861.6279
ENSG00000171824homo_sapiensENSP0000036613537.966128.9266petromyzon_marinusENSPMAP0000000762968.571452.2449
ENSG00000171824homo_sapiensENSP0000036613518.870115.0282petromyzon_marinusENSPMAP0000000012675.225259.9099
ENSG00000171824homo_sapiensENSP0000036613539.20925.6497eptatretus_burgeriENSEBUP0000000664556.514736.9707
ENSG00000171824homo_sapiensENSP0000036613576.158261.4689callorhinchus_miliiENSCMIP0000000433175.475960.9183
ENSG00000171824homo_sapiensENSP0000036613582.711968.3616latimeria_chalumnaeENSLACP0000001897280.439666.4835
ENSG00000171824homo_sapiensENSP0000036613578.418165.0847lepisosteus_oculatusENSLOCP0000000780677.282964.1425
ENSG00000171824homo_sapiensENSP0000036613571.412456.9492clupea_harengusENSCHAP0000004110271.981857.4032
ENSG00000171824homo_sapiensENSP0000036613574.463359.887danio_rerioENSDARP0000012267673.303758.9544
ENSG00000171824homo_sapiensENSP0000036613574.011359.322carassius_auratusENSCARP0000001630053.208842.6483
ENSG00000171824homo_sapiensENSP0000036613574.915359.661astyanax_mexicanusENSAMXP0000001493071.061156.5916
ENSG00000171824homo_sapiensENSP0000036613575.028359.548ictalurus_punctatusENSIPUP0000003268173.777858.5556
ENSG00000171824homo_sapiensENSP0000036613575.367261.3559esox_luciusENSELUP0000003432774.111160.3333
ENSG00000171824homo_sapiensENSP0000036613574.689359.774electrophorus_electricusENSEEEP0000004108074.520959.6392
ENSG00000171824homo_sapiensENSP0000036613574.463360.113oncorhynchus_kisutchENSOKIP0000502841670.556756.9593
ENSG00000171824homo_sapiensENSP0000036613574.576360.226oncorhynchus_mykissENSOMYP0000004122970.663857.0664
ENSG00000171824homo_sapiensENSP0000036613569.943556.7232salmo_salarENSSSAP0000011433769.943556.7232
ENSG00000171824homo_sapiensENSP0000036613574.802360.452salmo_truttaENSSTUP0000008858872.428958.5339
ENSG00000171824homo_sapiensENSP0000036613573.446357.7401gadus_morhuaENSGMOP0000005729066.258952.0897
ENSG00000171824homo_sapiensENSP0000036613575.480260.226fundulus_heteroclitusENSFHEP0000000936775.140659.955
ENSG00000171824homo_sapiensENSP0000036613575.367261.0169poecilia_reticulataENSPREP0000002414874.775860.5381
ENSG00000171824homo_sapiensENSP0000036613575.254261.0169xiphophorus_maculatusENSXMAP0000001129074.747560.6061
ENSG00000171824homo_sapiensENSP0000036613576.384261.5819oryzias_latipesENSORLP0000000645575.869861.1672
ENSG00000171824homo_sapiensENSP0000036613575.141260.226cyclopterus_lumpusENSCLMP0000501772773.643459.0255
ENSG00000171824homo_sapiensENSP0000036613576.158261.3559oreochromis_niloticusENSONIP0000000290175.475960.8063
ENSG00000171824homo_sapiensENSP0000036613570.960457.9661haplochromis_burtoniENSHBUP0000003338972.853859.5128
ENSG00000171824homo_sapiensENSP0000036613575.367261.0169astatotilapia_callipteraENSACLP0000003731774.943860.6742
ENSG00000171824homo_sapiensENSP0000036613575.141260.113sparus_aurataENSSAUP0001002443474.468159.5745
ENSG00000171824homo_sapiensENSP0000036613570.960458.7571lates_calcariferENSLCAP0001000921176.121263.0303
ENSG00000171824homo_sapiensENSP0000036613578.305164.7458xenopus_tropicalisENSXETP0000001385377.257563.8796
ENSG00000171824homo_sapiensENSP0000036613585.084774.0113chrysemys_picta_belliiENSCPBP0000003134383.481272.6164
ENSG00000171824homo_sapiensENSP0000036613582.824972.0904sphenodon_punctatusENSSPUP0000000897886.745675.503
ENSG00000171824homo_sapiensENSP0000036613580.56569.4915crocodylus_porosusENSCPRP0000500673281.859970.6085
ENSG00000171824homo_sapiensENSP0000036613578.757166.3277laticauda_laticaudataENSLLTP0000001022778.314665.9551
ENSG00000171824homo_sapiensENSP0000036613564.293855.5932notechis_scutatusENSNSUP0000002623672.669262.8353
ENSG00000171824homo_sapiensENSP0000036613559.54852.0904pseudonaja_textilisENSPTXP0000000916585.137374.475
ENSG00000171824homo_sapiensENSP0000036613578.305167.9096anas_platyrhynchos_platyrhynchosENSAPLP0000000633385.980174.5658
ENSG00000171824homo_sapiensENSP0000036613581.807970.3955gallus_gallusENSGALP0001003173785.276873.3804
ENSG00000171824homo_sapiensENSP0000036613581.807969.9435meleagris_gallopavoENSMGAP0000000457285.276872.9093
ENSG00000171824homo_sapiensENSP0000036613581.694969.8305serinus_canariaENSSCAP0000000397480.60268.8963
ENSG00000171824homo_sapiensENSP0000036613581.355968.7006parus_majorENSPMJP000000035748067.5556
ENSG00000171824homo_sapiensENSP0000036613571.186458.0791neolamprologus_brichardiENSNBRP0000000808675.995262.0024
ENSG00000171824homo_sapiensENSP0000036613569.039658.9831naja_najaENSNNAP0000002254480.820169.0476
ENSG00000171824homo_sapiensENSP0000036613572.881462.7119podarcis_muralisENSPMRP0000002185575.174864.6853
ENSG00000171824homo_sapiensENSP0000036613574.802363.7288geospiza_fortisENSGFOP0000001835781.829469.7157
ENSG00000171824homo_sapiensENSP0000036613581.468969.8305taeniopygia_guttataENSTGUP0000002708680.468868.9732
ENSG00000171824homo_sapiensENSP0000036613576.271261.3559erpetoichthys_calabaricusENSECRP0000002891872.424958.2618
ENSG00000171824homo_sapiensENSP0000036613575.480260kryptolebias_marmoratusENSKMAP0000002090775.39559.9323
ENSG00000171824homo_sapiensENSP0000036613574.915364.6328salvator_merianaeENSSMRP0000002021678.276367.5325
ENSG00000171824homo_sapiensENSP0000036613570.169556.6102amphilophus_citrinellusENSACIP0000002640575.181660.6538
ENSG00000171824homo_sapiensENSP0000036613576.271261.4689dicentrarchus_labraxENSDLAP0000505858375.587960.9183
ENSG00000171824homo_sapiensENSP0000036613576.158261.4689amphiprion_perculaENSAPEP0000002507874.805860.3774
ENSG00000171824homo_sapiensENSP0000036613576.158261.4689oryzias_sinensisENSOSIP0000000170275.645361.055
ENSG00000171824homo_sapiensENSP0000036613584.519872.9943pelodiscus_sinensisENSPSIP0000000553482.926871.6186
ENSG00000171824homo_sapiensENSP0000036613584.971773.6723gopherus_evgoodeiENSGEVP0000501299983.370372.2838
ENSG00000171824homo_sapiensENSP0000036613584.293872.9943chelonoidis_abingdoniiENSCABP0000002360984.484773.1597
ENSG00000171824homo_sapiensENSP0000036613576.045261.3559seriola_dumeriliENSSDUP0000000907375.448460.8744
ENSG00000171824homo_sapiensENSP0000036613576.045260.904cottoperca_gobioENSCGOP0000005415375.363960.3583
ENSG00000171824homo_sapiensENSP0000036613577.288166.1017struthio_camelus_australisENSSCUP0000000956984.863572.5806
ENSG00000171824homo_sapiensENSP0000036613577.514167.6836anser_brachyrhynchusENSABRP0000002086977.426667.6072
ENSG00000171824homo_sapiensENSP0000036613575.028360.226gasterosteus_aculeatusENSGACP0000000935075.198260.3624
ENSG00000171824homo_sapiensENSP0000036613574.350359.322cynoglossus_semilaevisENSCSEP0000000836273.437558.5938
ENSG00000171824homo_sapiensENSP0000036613575.706261.1299poecilia_formosaENSPFOP0000000500775.196460.7183
ENSG00000171824homo_sapiensENSP0000036613575.819261.4689myripristis_murdjanENSMMDP0000500897075.1460.9183
ENSG00000171824homo_sapiensENSP0000036613576.045261.3559sander_luciopercaENSSLUP0000003062275.111660.6027
ENSG00000171824homo_sapiensENSP0000036613583.163870.6215strigops_habroptilaENSSHBP0000501321981.596569.2905
ENSG00000171824homo_sapiensENSP0000036613571.073458.5311amphiprion_ocellarisENSAOCP0000002885876.80163.2479
ENSG00000171824homo_sapiensENSP0000036613584.858874.1243terrapene_carolina_triunguisENSTMTP0000003007383.259472.7273
ENSG00000171824homo_sapiensENSP0000036613573.220358.5311hucho_huchoENSHHUP0000001934170.974856.736
ENSG00000171824homo_sapiensENSP0000036613576.158260.113betta_splendensENSBSLP0000002288675.055759.2428
ENSG00000171824homo_sapiensENSP0000036613575.706260.678pygocentrus_nattereriENSPNAP0000002172974.444459.6667
ENSG00000171824homo_sapiensENSP0000036613575.367261.5819anabas_testudineusENSATEP0000002490674.775861.0987
ENSG00000171824homo_sapiensENSP0000036613544.293831.8644ciona_savignyiENSCSAVP0000001542566.894248.1229
ENSG00000171824homo_sapiensENSP0000036613543.050825.1977saccharomyces_cerevisiaeYOR001W51.978230.4229
ENSG00000171824homo_sapiensENSP0000036613576.158261.4689seriola_lalandi_dorsalisENSSLDP0000003340375.560560.9865
ENSG00000171824homo_sapiensENSP0000036613575.932261.4689labrus_bergyltaENSLBEP0000002935575.25260.9183
ENSG00000171824homo_sapiensENSP0000036613575.593261.1299pundamilia_nyerereiENSPNYP0000000980375.168560.7865
ENSG00000171824homo_sapiensENSP0000036613575.480260.791mastacembelus_armatusENSMAMP0000002884175.3160.6539
ENSG00000171824homo_sapiensENSP0000036613576.836261.9209stegastes_partitusENSSPAP0000000924876.233261.435
ENSG00000171824homo_sapiensENSP0000036613572.994358.4181oncorhynchus_tshawytschaENSOTSP0000506682969.462455.5914
ENSG00000171824homo_sapiensENSP0000036613574.576360.113oncorhynchus_tshawytschaENSOTSP0000507727670.663856.9593
ENSG00000171824homo_sapiensENSP0000036613576.158261.8079acanthochromis_polyacanthusENSAPOP0000001073375.560561.3229
ENSG00000171824homo_sapiensENSP0000036613584.293872.5424aquila_chrysaetos_chrysaetosENSACCP0002002044082.522171.0177
ENSG00000171824homo_sapiensENSP0000036613575.706260.339nothobranchius_furzeriENSNFUP0001505374575.535560.2029
ENSG00000171824homo_sapiensENSP0000036613575.593261.0169cyprinodon_variegatusENSCVAP0000001380575.337860.8108
ENSG00000171824homo_sapiensENSP0000036613573.672358.4181denticeps_clupeoidesENSDCDP0000003243973.012357.8947
ENSG00000171824homo_sapiensENSP0000036613575.706261.1299larimichthys_croceaENSLCRP0000502730775.196460.7183
ENSG00000171824homo_sapiensENSP0000036613574.463359.774takifugu_rubripesENSTRUP0000003162073.878959.3049
ENSG00000171824homo_sapiensENSP0000036613581.920970.6215ficedula_albicollisENSFALP0000001072980.73569.5991
ENSG00000171824homo_sapiensENSP0000036613575.819260.226hippocampus_comesENSHCOP0000002580575.393359.8876
ENSG00000171824homo_sapiensENSP0000036613572.881458.6441cyprinus_carpio_carpioENSCCRP0000017500773.630159.2466
ENSG00000171824homo_sapiensENSP0000036613574.124359.209cyprinus_carpio_carpioENSCCRP0000001551469.565255.5673
ENSG00000171824homo_sapiensENSP0000036613583.954872.3164coturnix_japonicaENSCJPP0000502053381.828270.4846
ENSG00000171824homo_sapiensENSP0000036613575.593260.904poecilia_latipinnaENSPLAP000000077627560.426
ENSG00000171824homo_sapiensENSP0000036613563.728851.9774sinocyclocheilus_grahamiENSSGRP0000007578972.493659.126
ENSG00000171824homo_sapiensENSP0000036613574.237360sinocyclocheilus_grahamiENSSGRP0000008573473.325959.2634
ENSG00000171824homo_sapiensENSP0000036613575.367261.0169maylandia_zebraENSMZEP0000501828574.943860.6742
ENSG00000171824homo_sapiensENSP0000036613573.559359.774tetraodon_nigroviridisENSTNIP0000000289674.913760.8746
ENSG00000171824homo_sapiensENSP0000036613573.785358.9831paramormyrops_kingsleyaeENSPKIP0000003334871.916357.489
ENSG00000171824homo_sapiensENSP0000036613574.576360.452scleropages_formosusENSSFOP0001504282273.578659.6433
ENSG00000171824homo_sapiensENSP0000036613574.915361.5819leptobrachium_leishanenseENSLLEP0000004398877.725763.8921
ENSG00000171824homo_sapiensENSP0000036613572.655460.678leptobrachium_leishanenseENSLLEP0000003282478.414665.4878
ENSG00000171824homo_sapiensENSP0000036613576.045261.5819scophthalmus_maximusENSSMAP0000002830875.279660.962
ENSG00000171824homo_sapiensENSP0000036613575.593261.0169oryzias_melastigmaENSOMEP0000000237475.084260.6061

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000166enables nucleotide binding1IEAHomo_sapiens(9606)Function
GO:0000175enables 3-5-RNA exonuclease activity3IBA,IMP,TASHomo_sapiens(9606)Function
GO:0000176part_of nuclear exosome (RNase complex)3IBA,IDA,NASHomo_sapiens(9606)Component
GO:0000177part_of cytoplasmic exosome (RNase complex)1NASHomo_sapiens(9606)Component
GO:0000178part_of exosome (RNase complex)1IDAHomo_sapiens(9606)Component
GO:0000184involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1IEAHomo_sapiens(9606)Process
GO:0000460involved_in maturation of 5.8S rRNA1IMPHomo_sapiens(9606)Process
GO:0000467involved_in exonucleolytic trimming to generate mature 3-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)1IBAHomo_sapiens(9606)Process
GO:0000791part_of euchromatin1IMPHomo_sapiens(9606)Component
GO:0000956involved_in nuclear-transcribed mRNA catabolic process1IMPHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003727enables single-stranded RNA binding1IBAHomo_sapiens(9606)Function
GO:0004532enables RNA exonuclease activity1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005730is_active_in nucleolus2IBA,IDAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0006364involved_in rRNA processing1TASHomo_sapiens(9606)Process
GO:0006396involved_in RNA processing1IDAHomo_sapiens(9606)Process
GO:0006401involved_in RNA catabolic process1IDAHomo_sapiens(9606)Process
GO:0009048involved_in dosage compensation by inactivation of X chromosome1IEAHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0032040part_of small-subunit processome1IDAHomo_sapiens(9606)Component
GO:0032211involved_in negative regulation of telomere maintenance via telomerase1IMPHomo_sapiens(9606)Process
GO:0042274involved_in ribosomal small subunit biogenesis1IDAHomo_sapiens(9606)Process
GO:0070034enables telomerase RNA binding1ICHomo_sapiens(9606)Function
GO:0071028involved_in nuclear mRNA surveillance1IMPHomo_sapiens(9606)Process
GO:0071034involved_in CUT catabolic process1IMPHomo_sapiens(9606)Process
GO:0071035involved_in nuclear polyadenylation-dependent rRNA catabolic process2IBA,IMPHomo_sapiens(9606)Process
GO:0071036involved_in nuclear polyadenylation-dependent snoRNA catabolic process1IBAHomo_sapiens(9606)Process
GO:0071037involved_in nuclear polyadenylation-dependent snRNA catabolic process1IBAHomo_sapiens(9606)Process
GO:0071038involved_in nuclear polyadenylation-dependent tRNA catabolic process1IBAHomo_sapiens(9606)Process
GO:0071039involved_in nuclear polyadenylation-dependent CUT catabolic process1IBAHomo_sapiens(9606)Process
GO:0071040involved_in nuclear polyadenylation-dependent antisense transcript catabolic process1IBAHomo_sapiens(9606)Process
GO:0071044involved_in histone mRNA catabolic process2IBA,IMPHomo_sapiens(9606)Process
GO:0071051involved_in polyadenylation-dependent snoRNA 3-end processing1IBAHomo_sapiens(9606)Process
GO:0101019part_of nucleolar exosome (RNase complex)1NASHomo_sapiens(9606)Component
GO:1904872involved_in regulation of telomerase RNA localization to Cajal body1IMPHomo_sapiens(9606)Process

Expression