Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs rRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000171421 Gene ID 64979 Accession 14490
Symbol MRPL36 Alias RPMJ;BRIP1;L36mt;bL36m;PRPL36;MRP-L36 Full Name mitochondrial ribosomal protein L36
Status Confidence Length 2982 bases Strand Minus strand
Position 5 : 1798385 - 1801366 RNA binding domain Ribosomal_L36
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 2p. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000372093 Ribosomal_L36 PF00444 1.1e-15 1
ENSP00000423152 Ribosomal_L36 PF00444 1.1e-15 1
ENSP00000423399 Ribosomal_L36 PF00444 1.1e-15 1
ENSP00000427152 Ribosomal_L36 PF00444 1.1e-15 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
MRPL36-202 ENST00000505059 609 103aa ENSP00000423152
MRPL36-203 ENST00000505818 595 103aa ENSP00000427152
MRPL36-204 ENST00000508987 686 103aa ENSP00000423399
MRPL36-201 ENST00000382647 587 103aa ENSP00000372093
MRPL36-205 ENST00000510999 793 35aa ENSP00000424366

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000171421

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000171421homo_sapiensENSP0000042315294.174893.2039nomascus_leucogenysENSNLEP000000135939796
ENSG00000171421homo_sapiensENSP00000423152100100pan_paniscusENSPPAP00000002859100100
ENSG00000171421homo_sapiensENSP0000042315298.058396.1165pongo_abeliiENSPPYP0000001711685.593283.8983
ENSG00000171421homo_sapiensENSP0000042315297.087494.1748pan_troglodytesENSPTRP0000007829397.087494.1748
ENSG00000171421homo_sapiensENSP00000423152100100pan_troglodytesENSPTRP00000028666100100
ENSG00000171421homo_sapiensENSP0000042315299.029196.1165gorilla_gorillaENSGGOP0000003639899.029196.1165
ENSG00000171421homo_sapiensENSP0000042315210098.0583gorilla_gorillaENSGGOP0000001654010098.0583
ENSG00000171421homo_sapiensENSP0000042315272.815558.2524sarcophilus_harrisiiENSSHAP0000003825866.371753.0973
ENSG00000171421homo_sapiensENSP0000042315271.844755.3398notamacropus_eugeniiENSMEUP0000000274366.666751.3514
ENSG00000171421homo_sapiensENSP0000042315275.728263.1068dasypus_novemcinctusENSDNOP0000003512463.414652.8455
ENSG00000171421homo_sapiensENSP0000042315288.349583.4951callithrix_jacchusENSCJAP0000004131888.349583.4951
ENSG00000171421homo_sapiensENSP0000042315290.291387.3786callithrix_jacchusENSCJAP0000006286890.291387.3786
ENSG00000171421homo_sapiensENSP0000042315291.262187.3786macaca_fascicularisENSMFAP0000005086436.015334.4828
ENSG00000171421homo_sapiensENSP0000042315291.262187.3786macaca_mulattaENSMMUP0000000592791.262187.3786
ENSG00000171421homo_sapiensENSP0000042315292.23387.3786papio_anubisENSPANP0000005811192.23387.3786
ENSG00000171421homo_sapiensENSP0000042315267.961256.3107vulpes_vulpesENSVVUP0000003061220.467816.9591
ENSG00000171421homo_sapiensENSP0000042315270.873858.2524mus_spretusMGP_SPRETEiJ_P003652371.568658.8235
ENSG00000171421homo_sapiensENSP0000042315274.757366.9903equus_asinusENSEASP0000506298430.923727.7108
ENSG00000171421homo_sapiensENSP0000042315243.689334.9515loxodonta_africanaENSLAFP0000000478273.770559.0164
ENSG00000171421homo_sapiensENSP0000042315265.048554.3689panthera_leoENSPLOP0000000537036.216230.2703
ENSG00000171421homo_sapiensENSP0000042315259.223349.5146bos_indicus_hybridENSBIXP000050247426151
ENSG00000171421homo_sapiensENSP0000042315255.339845.6311oryctolagus_cuniculusENSOCUP0000002026567.058855.2941
ENSG00000171421homo_sapiensENSP0000042315274.757366.9903equus_caballusENSECAP0000005943471.962664.486
ENSG00000171421homo_sapiensENSP0000042315267.961256.3107canis_lupus_familiarisENSCAFP0084503462563.636452.7273
ENSG00000171421homo_sapiensENSP0000042315256.310744.6602marmota_marmota_marmotaENSMMMP0000001849955.769244.2308
ENSG00000171421homo_sapiensENSP0000042315260.194251.4563balaenoptera_musculusENSBMSP0001001988261.386152.4752
ENSG00000171421homo_sapiensENSP0000042315263.106852.4272cavia_porcellusENSCPOP0000002997063.725552.9412
ENSG00000171421homo_sapiensENSP0000042315265.048554.3689felis_catusENSFCAP000000249796756
ENSG00000171421homo_sapiensENSP0000042315265.048554.3689felis_catusENSFCAP000000171376756
ENSG00000171421homo_sapiensENSP0000042315264.077753.3981ursus_americanusENSUAMP0000001760258.928649.1071
ENSG00000171421homo_sapiensENSP0000042315269.902955.3398monodelphis_domesticaENSMODP0000003697164.864951.3514
ENSG00000171421homo_sapiensENSP0000042315259.223349.5146bison_bison_bisonENSBBBP000000086366151
ENSG00000171421homo_sapiensENSP0000042315261.16551.4563monodon_monocerosENSMMNP0001500702262.376252.4752
ENSG00000171421homo_sapiensENSP0000042315266.019454.3689sus_scrofaENSSSCP000000396826856
ENSG00000171421homo_sapiensENSP0000042315258.252446.6019octodon_degusENSODEP0000002502361.855749.4845
ENSG00000171421homo_sapiensENSP0000042315266.990356.3107jaculus_jaculusENSJJAP0000001535063.888953.7037
ENSG00000171421homo_sapiensENSP0000042315259.223347.5728ovis_aries_rambouilletENSOARP000200128966149
ENSG00000171421homo_sapiensENSP0000042315264.077753.3981ursus_maritimusENSUMAP0000002971658.928649.1071
ENSG00000171421homo_sapiensENSP0000042315260.194249.5146delphinapterus_leucasENSDLEP0000000506030.392225
ENSG00000171421homo_sapiensENSP0000042315261.16550.4854physeter_catodonENSPCTP0000500216362.376251.4851
ENSG00000171421homo_sapiensENSP0000042315268.93259.2233mus_caroliMGP_CAROLIEiJ_P003485269.607859.8039
ENSG00000171421homo_sapiensENSP0000042315270.873858.2524mus_musculusENSMUSP0000002209871.568658.8235
ENSG00000171421homo_sapiensENSP0000042315285.436981.5534aotus_nancymaaeENSANAP000000243238884
ENSG00000171421homo_sapiensENSP0000042315278.640870.8738saimiri_boliviensis_boliviensisENSSBOP0000000788487.096878.4946
ENSG00000171421homo_sapiensENSP0000042315292.23386.4078chlorocebus_sabaeusENSCSAP0000001850192.23386.4078
ENSG00000171421homo_sapiensENSP0000042315261.16551.4563phocoena_sinusENSPSNP0000000277133.333328.0423
ENSG00000171421homo_sapiensENSP0000042315264.077753.3981camelus_dromedariusENSCDRP0000500901771.739159.7826
ENSG00000171421homo_sapiensENSP0000042315266.990355.3398rattus_norvegicusENSRNOP0000009297871.13458.7629
ENSG00000171421homo_sapiensENSP0000042315271.844761.165microtus_ochrogasterENSMOCP0000000540672.54961.7647
ENSG00000171421homo_sapiensENSP0000042315271.844760.1942peromyscus_maniculatus_bairdiiENSPEMP0000000425271.153859.6154
ENSG00000171421homo_sapiensENSP0000042315270.873858.2524mus_spicilegusENSMSIP0000002022371.568658.8235
ENSG00000171421homo_sapiensENSP0000042315265.048553.3981mus_spicilegusENSMSIP0000002459966.336654.4554
ENSG00000171421homo_sapiensENSP0000042315268.93257.2816cricetulus_griseus_chok1gshdENSCGRP0000100607869.607857.8431
ENSG00000171421homo_sapiensENSP0000042315268.93261.165pteropus_vampyrusENSPVAP0000000162764.545557.2727
ENSG00000171421homo_sapiensENSP0000042315271.844755.3398vombatus_ursinusENSVURP0001002813666.666751.3514
ENSG00000171421homo_sapiensENSP0000042315271.844758.2524rhinolophus_ferrumequinumENSRFEP0001000318169.811356.6038
ENSG00000171421homo_sapiensENSP0000042315259.223349.5146bos_taurusENSBTAP000000721806151
ENSG00000171421homo_sapiensENSP0000042315259.223348.5437heterocephalus_glaber_femaleENSHGLP0000003759745.522437.3134
ENSG00000171421homo_sapiensENSP0000042315267.961256.3107canis_lupus_dingoENSCAFP0002002932463.636452.7273
ENSG00000171421homo_sapiensENSP0000042315252.427247.5728sciurus_vulgarisENSSVLP0000500897754.545549.4949
ENSG00000171421homo_sapiensENSP0000042315251.456346.6019sciurus_vulgarisENSSVLP0000500645453.535448.4848
ENSG00000171421homo_sapiensENSP0000042315272.815555.3398phascolarctos_cinereusENSPCIP000000076096045.6
ENSG00000171421homo_sapiensENSP0000042315269.902960.1942nannospalax_galiliENSNGAP0000000093669.230859.6154
ENSG00000171421homo_sapiensENSP0000042315259.223349.5146bos_grunniensENSBGRP000000134846151
ENSG00000171421homo_sapiensENSP0000042315260.194248.5437cervus_hanglu_yarkandensisENSCHYP000000289066250
ENSG00000171421homo_sapiensENSP0000042315265.048556.3107catagonus_wagneriENSCWAP000000000266758
ENSG00000171421homo_sapiensENSP0000042315251.456344.6602ictidomys_tridecemlineatusENSSTOP0000002940555.789548.4211
ENSG00000171421homo_sapiensENSP0000042315266.990361.165otolemur_garnettiiENSOGAP0000002141371.87565.625
ENSG00000171421homo_sapiensENSP0000042315282.524375.7282cebus_imitatorENSCCAP0000003393873.91367.8261
ENSG00000171421homo_sapiensENSP0000042315253.398145.6311urocitellus_parryiiENSUPAP0001001429057.894749.4737
ENSG00000171421homo_sapiensENSP0000042315259.223347.5728moschus_moschiferusENSMMSP000000253206149
ENSG00000171421homo_sapiensENSP0000042315286.407881.5534rhinopithecus_roxellanaENSRROP0000000314091.752686.5979
ENSG00000171421homo_sapiensENSP0000042315271.844760.1942mus_pahariMGP_PahariEiJ_P002651772.54960.7843
ENSG00000171421homo_sapiensENSP0000042315235.922322.3301caenorhabditis_elegansK11H3.6.148.051929.8701
ENSG00000171421homo_sapiensENSP0000042315238.83531.068drosophila_melanogasterFBpp007645831.2525
ENSG00000171421homo_sapiensENSP0000042315259.223343.6893callorhinchus_miliiENSCMIP0000003931552.586238.7931
ENSG00000171421homo_sapiensENSP0000042315258.252444.6602latimeria_chalumnaeENSLACP0000000493752.173940
ENSG00000171421homo_sapiensENSP0000042315254.368940.7767lepisosteus_oculatusENSLOCP0000001079346.28134.7107
ENSG00000171421homo_sapiensENSP0000042315251.456339.8058clupea_harengusENSCHAP0000004873244.537834.4538
ENSG00000171421homo_sapiensENSP0000042315247.572833.9806danio_rerioENSDARP0000009463842.241430.1724
ENSG00000171421homo_sapiensENSP0000042315251.456338.835carassius_auratusENSCARP0000009894344.537833.6134
ENSG00000171421homo_sapiensENSP0000042315242.718433.9806astyanax_mexicanusENSAMXP0000002754525.73120.4678
ENSG00000171421homo_sapiensENSP0000042315248.543734.9515ictalurus_punctatusENSIPUP0000002170750.505136.3636
ENSG00000171421homo_sapiensENSP0000042315249.514639.8058esox_luciusENSELUP0000002526640.157532.2835
ENSG00000171421homo_sapiensENSP0000042315257.281641.7476electrophorus_electricusENSEEEP0000003773449.579836.1345
ENSG00000171421homo_sapiensENSP0000042315251.456339.8058oncorhynchus_kisutchENSOKIP0000503146942.432.8
ENSG00000171421homo_sapiensENSP0000042315250.485438.835oncorhynchus_mykissENSOMYP0000007538741.632
ENSG00000171421homo_sapiensENSP0000042315251.456338.835salmo_salarENSSSAP0000010140039.552229.8507
ENSG00000171421homo_sapiensENSP0000042315250.485439.8058salmo_salarENSSSAP0000014178729.545523.2955
ENSG00000171421homo_sapiensENSP0000042315250.485438.835salmo_truttaENSSTUP0000003553942.975233.0578
ENSG00000171421homo_sapiensENSP0000042315247.572835.9223gadus_morhuaENSGMOP0000004538839.837430.0813
ENSG00000171421homo_sapiensENSP0000042315249.514637.8641fundulus_heteroclitusENSFHEP0000001635443.965533.6207
ENSG00000171421homo_sapiensENSP0000042315252.427238.835poecilia_reticulataENSPREP000000256874533.3333
ENSG00000171421homo_sapiensENSP0000042315249.514639.8058xiphophorus_maculatusENSXMAP0000003343253.684243.1579
ENSG00000171421homo_sapiensENSP0000042315247.572834.9515oryzias_latipesENSORLP0000001789744.144132.4324
ENSG00000171421homo_sapiensENSP0000042315253.398137.8641cyclopterus_lumpusENSCLMP0000501433545.454532.2314
ENSG00000171421homo_sapiensENSP0000042315253.398138.835oreochromis_niloticusENSONIP0000002608635.256425.641
ENSG00000171421homo_sapiensENSP0000042315249.514638.835haplochromis_burtoniENSHBUP0000002005146.78936.6972
ENSG00000171421homo_sapiensENSP0000042315251.456333.9806sparus_aurataENSSAUP0001001960242.063527.7778
ENSG00000171421homo_sapiensENSP0000042315250.485431.068lates_calcariferENSLCAP0001005083453.608232.9897
ENSG00000171421homo_sapiensENSP0000042315251.456336.8932xenopus_tropicalisENSXETP0000009167737.062926.5734
ENSG00000171421homo_sapiensENSP0000042315259.223344.6602chrysemys_picta_belliiENSCPBP0000002375455.963342.2018
ENSG00000171421homo_sapiensENSP0000042315254.368937.8641crocodylus_porosusENSCPRP0000502029362.921343.8202
ENSG00000171421homo_sapiensENSP0000042315255.339842.7184anas_platyrhynchos_platyrhynchosENSAPLP0000002823756.435643.5644
ENSG00000171421homo_sapiensENSP0000042315253.398141.7476gallus_gallusENSGALP0001000989154.455442.5743
ENSG00000171421homo_sapiensENSP0000042315255.339844.6602parus_majorENSPMJP0000001840254.285743.8095
ENSG00000171421homo_sapiensENSP0000042315253.398138.835anolis_carolinensisENSACAP0000000070350.458736.6972
ENSG00000171421homo_sapiensENSP0000042315250.485437.8641neolamprologus_brichardiENSNBRP0000000156555.91441.9355
ENSG00000171421homo_sapiensENSP0000042315252.427236.8932erpetoichthys_calabaricusENSECRP0000001835248.648634.2342
ENSG00000171421homo_sapiensENSP0000042315250.485441.7476kryptolebias_marmoratusENSKMAP0000000129144.067836.4407
ENSG00000171421homo_sapiensENSP0000042315250.485436.8932oryzias_javanicusENSOJAP0000004172447.706434.8624
ENSG00000171421homo_sapiensENSP0000042315251.456337.8641oryzias_javanicusENSOJAP0000001203248.623935.7798
ENSG00000171421homo_sapiensENSP0000042315250.485436.8932amphilophus_citrinellusENSACIP0000001662841.269830.1587
ENSG00000171421homo_sapiensENSP0000042315251.456335.9223dicentrarchus_labraxENSDLAP0000500542942.741929.8387
ENSG00000171421homo_sapiensENSP0000042315243.689333.0097amphiprion_perculaENSAPEP0000000406841.284431.1927
ENSG00000171421homo_sapiensENSP0000042315248.543734.9515oryzias_sinensisENSOSIP0000000199043.859631.5789
ENSG00000171421homo_sapiensENSP0000042315248.543735.9223gopherus_evgoodeiENSGEVP0000500268555.555641.1111
ENSG00000171421homo_sapiensENSP0000042315264.077746.6019chelonoidis_abingdoniiENSCABP0000001219060.550544.0367
ENSG00000171421homo_sapiensENSP0000042315252.427239.8058seriola_dumeriliENSSDUP0000000247742.857132.5397
ENSG00000171421homo_sapiensENSP0000042315255.339836.8932myripristis_murdjanENSMMDP0000501716545.238130.1587
ENSG00000171421homo_sapiensENSP0000042315251.456336.8932sander_luciopercaENSSLUP0000005561542.063530.1587
ENSG00000171421homo_sapiensENSP0000042315255.339841.7476strigops_habroptilaENSSHBP0000500537250.442538.0531
ENSG00000171421homo_sapiensENSP0000042315246.601934.9515amphiprion_ocellarisENSAOCP0000001445444.036733.0275
ENSG00000171421homo_sapiensENSP0000042315260.194242.7184terrapene_carolina_triunguisENSTMTP0000001119556.880740.367
ENSG00000171421homo_sapiensENSP0000042315249.514638.835hucho_huchoENSHHUP0000006748940.832
ENSG00000171421homo_sapiensENSP0000042315250.485438.835hucho_huchoENSHHUP0000005219841.632
ENSG00000171421homo_sapiensENSP0000042315249.514633.9806betta_splendensENSBSLP0000001313641.12928.2258
ENSG00000171421homo_sapiensENSP0000042315249.514639.8058pygocentrus_nattereriENSPNAP0000002220342.857134.4538
ENSG00000171421homo_sapiensENSP0000042315249.514633.0097anabas_testudineusENSATEP0000001020040.827.2
ENSG00000171421homo_sapiensENSP0000042315251.456337.8641seriola_lalandi_dorsalisENSSLDP0000000584042.063530.9524
ENSG00000171421homo_sapiensENSP0000042315250.485435.9223labrus_bergyltaENSLBEP0000002432831.137722.1557
ENSG00000171421homo_sapiensENSP0000042315252.427239.8058pundamilia_nyerereiENSPNYP0000001385849.541337.6147
ENSG00000171421homo_sapiensENSP0000042315248.543734.9515mastacembelus_armatusENSMAMP0000000695739.682528.5714
ENSG00000171421homo_sapiensENSP0000042315249.514636.8932stegastes_partitusENSSPAP0000002316640.476230.1587
ENSG00000171421homo_sapiensENSP0000042315250.485439.8058oncorhynchus_tshawytschaENSOTSP0000507221641.632.8
ENSG00000171421homo_sapiensENSP0000042315242.718429.1262acanthochromis_polyacanthusENSAPOP0000002352144.444430.303
ENSG00000171421homo_sapiensENSP0000042315252.427240.7767aquila_chrysaetos_chrysaetosENSACCP0002000334842.857133.3333
ENSG00000171421homo_sapiensENSP0000042315252.427238.835nothobranchius_furzeriENSNFUP0001502749144.262332.7869
ENSG00000171421homo_sapiensENSP0000042315246.601935.9223cyprinodon_variegatusENSCVAP000000288885038.5417
ENSG00000171421homo_sapiensENSP0000042315251.456338.835denticeps_clupeoidesENSDCDP0000005156746.491235.0877
ENSG00000171421homo_sapiensENSP0000042315250.485437.8641larimichthys_croceaENSLCRP0000503592732.911424.6835
ENSG00000171421homo_sapiensENSP0000042315252.427237.8641takifugu_rubripesENSTRUP0000004789343.548431.4516
ENSG00000171421homo_sapiensENSP0000042315250.485433.9806hippocampus_comesENSHCOP0000002815144.444429.9145
ENSG00000171421homo_sapiensENSP0000042315250.485436.8932cyprinus_carpio_carpioENSCCRP0000016664343.697531.9328
ENSG00000171421homo_sapiensENSP0000042315252.427239.8058cyprinus_carpio_carpioENSCCRP0000017987445.378234.4538
ENSG00000171421homo_sapiensENSP0000042315255.339842.7184coturnix_japonicaENSCJPP0000501818656.435643.5644
ENSG00000171421homo_sapiensENSP0000042315248.543734.9515poecilia_latipinnaENSPLAP0000000471045.04532.4324
ENSG00000171421homo_sapiensENSP0000042315250.485437.8641poecilia_latipinnaENSPLAP0000002874143.333332.5
ENSG00000171421homo_sapiensENSP0000042315251.456338.835sinocyclocheilus_grahamiENSSGRP0000002737644.537833.6134
ENSG00000171421homo_sapiensENSP0000042315249.514637.8641sinocyclocheilus_grahamiENSSGRP0000004240343.220333.0508
ENSG00000171421homo_sapiensENSP0000042315250.485434.9515maylandia_zebraENSMZEP0000500023549.523834.2857
ENSG00000171421homo_sapiensENSP0000042315250.485437.8641tetraodon_nigroviridisENSTNIP0000000012541.631.2
ENSG00000171421homo_sapiensENSP0000042315246.601933.0097paramormyrops_kingsleyaeENSPKIP0000000897744.859831.7757
ENSG00000171421homo_sapiensENSP0000042315252.427240.7767scleropages_formosusENSSFOP0001500214546.551736.2069
ENSG00000171421homo_sapiensENSP0000042315250.485438.835scophthalmus_maximusENSSMAP0000003372541.269831.746
ENSG00000171421homo_sapiensENSP0000042315253.398140.7767oryzias_melastigmaENSOMEP0000001199349.549537.8378

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003735enables structural constituent of ribosome1IEAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005739located_in mitochondrion1IDAHomo_sapiens(9606)Component
GO:0005743located_in mitochondrial inner membrane2NAS,TASHomo_sapiens(9606)Component
GO:0005762part_of mitochondrial large ribosomal subunit3IBA,IDA,NASHomo_sapiens(9606)Component
GO:0006412involved_in translation1NASHomo_sapiens(9606)Process
GO:0016604located_in nuclear body1IDAHomo_sapiens(9606)Component
GO:0032543involved_in mitochondrial translation1NASHomo_sapiens(9606)Process

Expression