Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs diverse
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000169397 Gene ID 6037 Accession 10046
Symbol RNASE3 Alias ECP;RAF1;RNS3 Full Name ribonuclease A family member 3
Status Confidence Length 964 bases Strand Plus strand
Position 14 : 20891385 - 20892348 RNA binding domain RnaseA
Summary The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria [provided by RefSeq, Oct 2014]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000302324 RnaseA PF00074 1.8e-33 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
25170926 Complete genomic sequence and comparative analysis of the genome segments of sweet potato chlorotic stunt virus in China. Yanhong Qin 2014-01-01 PloS one
24278443 Genetic variability and evolutionary implications of RNA silencing suppressor genes in RNA1 of sweet potato chlorotic stunt virus isolates infecting sweetpotato and related wild species. K Arthur Tugume 2013-01-01 PloS one

Transcripts

Name Transcript ID bp Protein Translation ID
RNASE3-201 ENST00000304639 734 160aa ENSP00000302324

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
100095Nose3E-827560520

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000169397homo_sapiensENSP0000030327678.260968.9441homo_sapiensENSP0000030232478.7569.375
ENSG00000169397homo_sapiensENSP0000051286723.129312.9252homo_sapiensENSP0000030232421.2511.875
ENSG00000169397homo_sapiensENSP0000029869053.846239.1026homo_sapiensENSP0000030232452.538.125
ENSG00000169397homo_sapiensENSP0000031139852.597438.961homo_sapiensENSP0000030232450.62537.5
ENSG00000169397homo_sapiensENSP0000030204657.333344homo_sapiensENSP0000030232453.7541.25
ENSG00000169397homo_sapiensENSP0000039299623.611116.6667homo_sapiensENSP0000030232431.87522.5
ENSG00000169397homo_sapiensENSP0000045131818.59310.5528homo_sapiensENSP0000030232423.12513.125
ENSG00000169397homo_sapiensENSP0000038107734.013623.8095homo_sapiensENSP0000030232431.2521.875
ENSG00000169397homo_sapiensENSP0000038468326.666712.8571homo_sapiensENSP000003023243516.875
ENSG00000169397homo_sapiensENSP0000038105741.666727.5641homo_sapiensENSP0000030232440.62526.875
ENSG00000169397homo_sapiensENSP0000045224539.455825.8503homo_sapiensENSP0000030232436.2523.75
ENSG00000169397homo_sapiensENSP0000037241026.923114.7436homo_sapiensENSP0000030232426.2514.375

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000169397homo_sapiensENSP0000030232486.2576.875pongo_abeliiENSPPYP0000000634786.2576.875
ENSG00000169397homo_sapiensENSP0000030232498.12597.5gorilla_gorillaENSGGOP0000001712298.12597.5
ENSG00000169397homo_sapiensENSP0000030232463.7548.75dasypus_novemcinctusENSDNOP0000001829064.968249.6815
ENSG00000169397homo_sapiensENSP0000030232458.7545dasypus_novemcinctusENSDNOP0000002729659.872645.8599
ENSG00000169397homo_sapiensENSP0000030232478.7568.125callithrix_jacchusENSCJAP0000001765179.746868.9873
ENSG00000169397homo_sapiensENSP0000030232483.7578.75cercocebus_atysENSCATP0000000734883.7578.75
ENSG00000169397homo_sapiensENSP000003023249590macaca_fascicularisENSMFAP000000112249590
ENSG00000169397homo_sapiensENSP0000030232483.7576.875macaca_fascicularisENSMFAP0000001121283.7576.875
ENSG00000169397homo_sapiensENSP0000030232484.37578.125macaca_mulattaENSMMUP0000002563184.37578.125
ENSG00000169397homo_sapiensENSP000003023249589.375macaca_mulattaENSMMUP000000331609589.375
ENSG00000169397homo_sapiensENSP0000030232493.7588.75macaca_nemestrinaENSMNEP0000000032793.7588.75
ENSG00000169397homo_sapiensENSP0000030232483.12576.25macaca_nemestrinaENSMNEP0000002955583.12576.25
ENSG00000169397homo_sapiensENSP0000030232482.576.25mandrillus_leucophaeusENSMLEP0000000069882.576.25
ENSG00000169397homo_sapiensENSP0000030232428.12521.875mus_spretusMGP_SPRETEiJ_P003822861.643847.9452
ENSG00000169397homo_sapiensENSP000003023242515mus_spretusMGP_SPRETEiJ_P003822630.30318.1818
ENSG00000169397homo_sapiensENSP000003023246046.875equus_asinusENSEASP0000501464260.377447.1698
ENSG00000169397homo_sapiensENSP0000030232464.37548.125capra_hircusENSCHIP0000000313665.189948.7342
ENSG00000169397homo_sapiensENSP0000030232428.7520.625ailuropoda_melanoleucaENSAMEP0000003198831.292522.449
ENSG00000169397homo_sapiensENSP0000030232453.7541.25bos_indicus_hybridENSBIXP0000501732235.983327.6151
ENSG00000169397homo_sapiensENSP000003023246550bos_indicus_hybridENSBIXP0000501619656.521743.4783
ENSG00000169397homo_sapiensENSP0000030232459.37546.25oryctolagus_cuniculusENSOCUP0000004370357.926845.122
ENSG00000169397homo_sapiensENSP0000030232461.2548.125oryctolagus_cuniculusENSOCUP0000001982462.820549.359
ENSG00000169397homo_sapiensENSP000003023246046.875oryctolagus_cuniculusENSOCUP0000002324856.804744.3787
ENSG00000169397homo_sapiensENSP0000030232460.62547.5equus_caballusENSECAP0000007932561.006347.7987
ENSG00000169397homo_sapiensENSP0000030232456.2541.25marmota_marmota_marmotaENSMMMP0000001690557.692342.3077
ENSG00000169397homo_sapiensENSP0000030232463.12548.75marmota_marmota_marmotaENSMMMP0000001690863.92449.3671
ENSG00000169397homo_sapiensENSP0000030232466.2549.375balaenoptera_musculusENSBMSP0001001219463.855447.5904
ENSG00000169397homo_sapiensENSP0000030232456.87542.5monodon_monocerosENSMMNP0001501299458.709743.871
ENSG00000169397homo_sapiensENSP0000030232463.12549.375sus_scrofaENSSSCP0000004209464.743650.641
ENSG00000169397homo_sapiensENSP0000030232464.37548.125ovis_aries_rambouilletENSOARP0002001741165.189948.7342
ENSG00000169397homo_sapiensENSP0000030232459.37543.75delphinapterus_leucasENSDLEP0000000233060.126644.3038
ENSG00000169397homo_sapiensENSP0000030232461.87545.625physeter_catodonENSPCTP0000500444862.658246.2025
ENSG00000169397homo_sapiensENSP0000030232459.37548.125mus_musculusENSMUSP0000009825661.290349.6774
ENSG00000169397homo_sapiensENSP0000030232460.62547.5mus_musculusENSMUSP0000012387262.179548.7179
ENSG00000169397homo_sapiensENSP0000030232456.87544.375mus_musculusENSMUSP0000007507458.709745.8064
ENSG00000169397homo_sapiensENSP000003023246046.875mus_musculusENSMUSP0000007438661.538548.0769
ENSG00000169397homo_sapiensENSP0000030232458.12546.875mus_musculusENSMUSP000000564186048.3871
ENSG00000169397homo_sapiensENSP000003023246043.75mus_musculusENSMUSP0000005629361.935545.1613
ENSG00000169397homo_sapiensENSP0000030232457.546.25mus_musculusENSMUSP0000012715259.354847.7419
ENSG00000169397homo_sapiensENSP0000030232461.87544.375dipodomys_ordiiENSDORP0000002367962.264244.6541
ENSG00000169397homo_sapiensENSP0000030232476.87569.375aotus_nancymaaeENSANAP0000000164777.848170.2532
ENSG00000169397homo_sapiensENSP000003023248070.625saimiri_boliviensis_boliviensisENSSBOP0000000149781.012771.519
ENSG00000169397homo_sapiensENSP000003023246045.625mesocricetus_auratusENSMAUP0000001825261.146546.4968
ENSG00000169397homo_sapiensENSP0000030232463.7546.875camelus_dromedariusENSCDRP0000500261564.150947.1698
ENSG00000169397homo_sapiensENSP0000030232460.62546.25rattus_norvegicusENSRNOP0000003926262.580647.7419
ENSG00000169397homo_sapiensENSP0000030232438.12530.625rattus_norvegicusENSRNOP0000009685358.653847.1154
ENSG00000169397homo_sapiensENSP000003023246047.5rattus_norvegicusENSRNOP0000009797761.538548.7179
ENSG00000169397homo_sapiensENSP000003023246048.125rattus_norvegicusENSRNOP0000007649061.935549.6774
ENSG00000169397homo_sapiensENSP0000030232458.12546.25rattus_norvegicusENSRNOP0000002164561.589449.0066
ENSG00000169397homo_sapiensENSP000003023246048.125rattus_norvegicusENSRNOP0000008414561.935549.6774
ENSG00000169397homo_sapiensENSP0000030232461.2548.75rattus_norvegicusENSRNOP0000005022563.225850.3226
ENSG00000169397homo_sapiensENSP0000030232468.7556.25prolemur_simusENSPSMP0000001741368.32355.9006
ENSG00000169397homo_sapiensENSP0000030232467.554.375prolemur_simusENSPSMP0000001742367.924554.717
ENSG00000169397homo_sapiensENSP0000030232461.2548.125peromyscus_maniculatus_bairdiiENSPEMP0000002797662.420449.0446
ENSG00000169397homo_sapiensENSP0000030232459.37543.75mus_spicilegusENSMSIP0000000209861.290345.1613
ENSG00000169397homo_sapiensENSP0000030232453.12539.375mus_spicilegusENSMSIP0000002668254.838740.6452
ENSG00000169397homo_sapiensENSP0000030232456.87544.375mus_spicilegusENSMSIP0000002313558.709745.8064
ENSG00000169397homo_sapiensENSP0000030232458.12546.875mus_spicilegusENSMSIP000000266746048.3871
ENSG00000169397homo_sapiensENSP000003023246046.875mus_spicilegusENSMSIP0000000780161.538548.0769
ENSG00000169397homo_sapiensENSP0000030232456.2546.875mus_spicilegusENSMSIP0000002316158.064548.3871
ENSG00000169397homo_sapiensENSP0000030232454.37543.125cricetulus_griseus_chok1gshdENSCGRP0000101404755.063343.6709
ENSG00000169397homo_sapiensENSP0000030232460.62547.5cricetulus_griseus_chok1gshdENSCGRP0000101451761.783448.4076
ENSG00000169397homo_sapiensENSP0000030232457.545cricetulus_griseus_chok1gshdENSCGRP0000101463158.227845.5696
ENSG00000169397homo_sapiensENSP000003023245036.875cricetulus_griseus_chok1gshdENSCGRP0000100754249.079836.1963
ENSG00000169397homo_sapiensENSP0000030232453.12543.75myotis_lucifugusENSMLUP0000002266561.594250.7246
ENSG00000169397homo_sapiensENSP0000030232457.543.75myotis_lucifugusENSMLUP0000001643759.740345.4545
ENSG00000169397homo_sapiensENSP0000030232459.37540.625rhinolophus_ferrumequinumENSRFEP0001002582458.64240.1235
ENSG00000169397homo_sapiensENSP0000030232464.37551.875bos_taurusENSBTAP0000003609255.978345.1087
ENSG00000169397homo_sapiensENSP0000030232462.550bos_taurusENSBTAP0000005915454.347843.4783
ENSG00000169397homo_sapiensENSP0000030232445.62536.25heterocephalus_glaber_femaleENSHGLP0000005415849.659939.4558
ENSG00000169397homo_sapiensENSP0000030232483.12576.875rhinopithecus_bietiENSRBIP0000000197883.12576.875
ENSG00000169397homo_sapiensENSP0000030232463.7550sciurus_vulgarisENSSVLP0000500193662.195148.7805
ENSG00000169397homo_sapiensENSP0000030232461.2545.625sciurus_vulgarisENSSVLP0000500192361.635245.9119
ENSG00000169397homo_sapiensENSP0000030232461.2546.25sciurus_vulgarisENSSVLP0000500195862.420447.1338
ENSG00000169397homo_sapiensENSP0000030232458.7546.875catagonus_wagneriENSCWAP0000000834659.493747.4684
ENSG00000169397homo_sapiensENSP000003023246550ictidomys_tridecemlineatusENSSTOP0000002318065.822850.6329
ENSG00000169397homo_sapiensENSP000003023246043.125ictidomys_tridecemlineatusENSSTOP0000002545855.81440.1163
ENSG00000169397homo_sapiensENSP0000030232461.87546.25ictidomys_tridecemlineatusENSSTOP0000001843262.658246.8354
ENSG00000169397homo_sapiensENSP0000030232470.62555otolemur_garnettiiENSOGAP0000001915871.069255.3459
ENSG00000169397homo_sapiensENSP000003023247054.375otolemur_garnettiiENSOGAP0000002201070.440354.717
ENSG00000169397homo_sapiensENSP0000030232466.2554.375otolemur_garnettiiENSOGAP0000001193666.666754.717
ENSG00000169397homo_sapiensENSP000003023247566.875cebus_imitatorENSCCAP0000000125675.949467.7215
ENSG00000169397homo_sapiensENSP0000030232458.7545urocitellus_parryiiENSUPAP0001000233658.024744.4444
ENSG00000169397homo_sapiensENSP0000030232464.37550urocitellus_parryiiENSUPAP0001000230465.189950.6329
ENSG00000169397homo_sapiensENSP0000030232467.553.75moschus_moschiferusENSMMSP0000001111868.354454.4304
ENSG00000169397homo_sapiensENSP0000030232437.530mus_pahariMGP_PahariEiJ_P008462657.142945.7143
ENSG00000169397homo_sapiensENSP0000030232426.87516.875chrysemys_picta_belliiENSCPBP0000002645529.054118.2432
ENSG00000169397homo_sapiensENSP0000030232426.87517.5chrysemys_picta_belliiENSCPBP0000002642535.245922.9508
ENSG00000169397homo_sapiensENSP0000030232431.87521.25laticauda_laticaudataENSLLTP0000001248037.525
ENSG00000169397homo_sapiensENSP0000030232433.12523.75laticauda_laticaudataENSLLTP0000001859137.857127.1429
ENSG00000169397homo_sapiensENSP0000030232430.62520.625laticauda_laticaudataENSLLTP0000000545922.374415.0685
ENSG00000169397homo_sapiensENSP0000030232429.37519.375notechis_scutatusENSNSUP0000002605732.867121.6783
ENSG00000169397homo_sapiensENSP0000030232431.87521.25notechis_scutatusENSNSUP0000000552037.525
ENSG00000169397homo_sapiensENSP000003023243020pseudonaja_textilisENSPTXP0000002409233.802822.5352
ENSG00000169397homo_sapiensENSP0000030232433.12520.625pseudonaja_textilisENSPTXP0000002317238.970624.2647
ENSG00000169397homo_sapiensENSP0000030232428.7518.75anas_platyrhynchos_platyrhynchosENSAPLP0000001124913.60958.87574
ENSG00000169397homo_sapiensENSP0000030232426.87516.875gallus_gallusENSGALP0001000385321.182313.3005
ENSG00000169397homo_sapiensENSP0000030232431.2520gallus_gallusENSGALP0001001560935.971223.0216
ENSG00000169397homo_sapiensENSP0000030232430.62520.625gallus_gallusENSGALP0001001172635.251823.741
ENSG00000169397homo_sapiensENSP0000030232425.62516.875meleagris_gallopavoENSMGAP0000000967428.275918.6207
ENSG00000169397homo_sapiensENSP000003023243016.25meleagris_gallopavoENSMGAP0000001710341.025622.2222
ENSG00000169397homo_sapiensENSP0000030232426.87518.125meleagris_gallopavoENSMGAP0000002640334.423.2
ENSG00000169397homo_sapiensENSP0000030232427.519.375meleagris_gallopavoENSMGAP0000003026637.606826.4957
ENSG00000169397homo_sapiensENSP0000030232423.7516.875serinus_canariaENSSCAP0000001661826.388918.75
ENSG00000169397homo_sapiensENSP0000030232426.87518.125parus_majorENSPMJP0000001385729.861120.1389
ENSG00000169397homo_sapiensENSP0000030232430.62521.25anolis_carolinensisENSACAP0000000771733.561623.2877
ENSG00000169397homo_sapiensENSP0000030232425.62516.875naja_najaENSNNAP0000001252133.884322.314
ENSG00000169397homo_sapiensENSP0000030232431.87520podarcis_muralisENSPMRP0000002515637.523.5294
ENSG00000169397homo_sapiensENSP0000030232431.87520podarcis_muralisENSPMRP0000002514737.523.5294
ENSG00000169397homo_sapiensENSP000003023243018.75podarcis_muralisENSPMRP0000003412230.188718.8679
ENSG00000169397homo_sapiensENSP0000030232428.12518.125podarcis_muralisENSPMRP0000002510931.690120.4225
ENSG00000169397homo_sapiensENSP0000030232433.7518.125podarcis_muralisENSPMRP0000001903433.333317.9012
ENSG00000169397homo_sapiensENSP0000030232428.12517.5podarcis_muralisENSPMRP0000001903837.523.3333
ENSG00000169397homo_sapiensENSP0000030232431.2519.375podarcis_muralisENSPMRP0000003410334.96521.6783
ENSG00000169397homo_sapiensENSP0000030232427.518.75taeniopygia_guttataENSTGUP0000000506230.555620.8333
ENSG00000169397homo_sapiensENSP0000030232430.62519.375salvator_merianaeENSSMRP0000000161831.818220.1299
ENSG00000169397homo_sapiensENSP0000030232429.37520.625salvator_merianaeENSSMRP0000000846025.405417.8378
ENSG00000169397homo_sapiensENSP0000030232421.87515salvator_merianaeENSSMRP0000000844924.822717.0213
ENSG00000169397homo_sapiensENSP0000030232428.7517.5salvator_merianaeENSSMRP0000000843531.724119.3103
ENSG00000169397homo_sapiensENSP0000030232428.7521.25gopherus_evgoodeiENSGEVP0000502132231.506823.2877
ENSG00000169397homo_sapiensENSP0000030232423.7517.5gopherus_evgoodeiENSGEVP0000502108531.40523.1405
ENSG00000169397homo_sapiensENSP0000030232430.62522.5chelonoidis_abingdoniiENSCABP0000001464233.108124.3243
ENSG00000169397homo_sapiensENSP0000030232423.12515chelonoidis_abingdoniiENSCABP0000000466622.981414.9068
ENSG00000169397homo_sapiensENSP0000030232431.87519.375chelonoidis_abingdoniiENSCABP0000001065225.515.5
ENSG00000169397homo_sapiensENSP0000030232428.7519.375struthio_camelus_australisENSSCUP0000000922632.857122.1429
ENSG00000169397homo_sapiensENSP0000030232425.62517.5anser_brachyrhynchusENSABRP0000000884728.275919.3103
ENSG00000169397homo_sapiensENSP0000030232425.62518.75strigops_habroptilaENSSHBP0000500073628.671320.979
ENSG00000169397homo_sapiensENSP0000030232430.62523.125terrapene_carolina_triunguisENSTMTP0000000859433.561625.3425
ENSG00000169397homo_sapiensENSP0000030232419.37512.5aquila_chrysaetos_chrysaetosENSACCP0002000548223.664115.2672
ENSG00000169397homo_sapiensENSP0000030232426.87518.75ficedula_albicollisENSFALP0000001489229.861120.8333
ENSG00000169397homo_sapiensENSP0000030232429.37517.5coturnix_japonicaENSCJPP0000501596833.81320.1439
ENSG00000169397homo_sapiensENSP0000030232431.2519.375coturnix_japonicaENSCJPP0000501596734.96521.6783
ENSG00000169397homo_sapiensENSP000003023242515.625coturnix_japonicaENSCJPP0000501596932.786920.4918
ENSG00000169397homo_sapiensENSP0000030232426.87518.125coturnix_japonicaENSCJPP0000501327129.655220

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001530enables lipopolysaccharide binding1IDAHomo_sapiens(9606)Function
GO:0002227involved_in innate immune response in mucosa2IBA,IDAHomo_sapiens(9606)Process
GO:0003676enables nucleic acid binding1IEAHomo_sapiens(9606)Function
GO:0004519enables endonuclease activity1IEAHomo_sapiens(9606)Function
GO:0004540enables RNA nuclease activity1IBAHomo_sapiens(9606)Function
GO:0005576located_in extracellular region1TASHomo_sapiens(9606)Component
GO:0005615is_active_in extracellular space2IBA,IDAHomo_sapiens(9606)Component
GO:0006401involved_in RNA catabolic process1TASHomo_sapiens(9606)Process
GO:0006935involved_in chemotaxis1IBAHomo_sapiens(9606)Process
GO:0019731involved_in antibacterial humoral response1IDAHomo_sapiens(9606)Process
GO:0035578located_in azurophil granule lumen1TASHomo_sapiens(9606)Component
GO:0043152involved_in induction of bacterial agglutination1IDAHomo_sapiens(9606)Process
GO:0045087involved_in innate immune response1IDAHomo_sapiens(9606)Process
GO:0050829involved_in defense response to Gram-negative bacterium1IDAHomo_sapiens(9606)Process
GO:0050830involved_in defense response to Gram-positive bacterium2IBA,IDAHomo_sapiens(9606)Process
GO:0061844involved_in antimicrobial humoral immune response mediated by antimicrobial peptide1IDAHomo_sapiens(9606)Process

Expression