Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions E3 ligase
Localizations N.A.
BulkPerturb-seq

Description

Ensembl ID ENSG00000167333 Gene ID 55128 Accession 21161
Symbol TRIM68 Alias SS56;GC109;SS-56;RNF137 Full Name tripartite motif containing 68
Status Confidence Length 9560 bases Strand Minus strand
Position 11 : 4598672 - 4608231 RNA binding domain SPRY
Summary

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000300747 SPRY PF00622 5.8e-14 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
TRIM68-201 ENST00000300747 3324 485aa ENSP00000300747
TRIM68-203 ENST00000531101 3187 187aa ENSP00000431783
TRIM68-202 ENST00000526337 874 142aa ENSP00000434681
TRIM68-205 ENST00000531717 566 No protein -
TRIM68-204 ENST00000531644 553 No protein -
TRIM68-206 ENST00000532108 1462 No protein -
TRIM68-207 ENST00000533021 764 198aa ENSP00000436112

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
18251Fetal Hemoglobin3.825e-005-
18252Fetal Hemoglobin3.825e-005-
18635Erythrocyte Indices4.933e-009-
18636Erythrocyte Indices4.933e-009-
18757Erythrocyte Indices2.002e-007-
18758Erythrocyte Indices2.002e-007-
18908Erythrocyte Count1.694e-006-
18909Erythrocyte Count1.694e-006-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000209involved_in protein polyubiquitination1IBAHomo_sapiens(9606)Process
GO:0004842enables ubiquitin-protein transferase activity1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005654is_active_in nucleoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1IDAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0005794located_in Golgi apparatus1IDAHomo_sapiens(9606)Component
GO:0005829is_active_in cytosol3IBA,IDA,TASHomo_sapiens(9606)Component
GO:0008270enables zinc ion binding1IEAHomo_sapiens(9606)Function
GO:0010508involved_in positive regulation of autophagy1IBAHomo_sapiens(9606)Process
GO:0019901enables protein kinase binding1IBAHomo_sapiens(9606)Function
GO:0032880involved_in regulation of protein localization1IBAHomo_sapiens(9606)Process
GO:0035035enables histone acetyltransferase binding1IPIHomo_sapiens(9606)Function
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0042803enables protein homodimerization activity1IBAHomo_sapiens(9606)Function
GO:0043123involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling1IBAHomo_sapiens(9606)Process
GO:0045087involved_in innate immune response1IBAHomo_sapiens(9606)Process
GO:0046596involved_in regulation of viral entry into host cell1IBAHomo_sapiens(9606)Process
GO:0048471located_in perinuclear region of cytoplasm1IEAHomo_sapiens(9606)Component
GO:0050681enables nuclear androgen receptor binding1IPIHomo_sapiens(9606)Function
GO:0051092involved_in positive regulation of NF-kappaB transcription factor activity1IBAHomo_sapiens(9606)Process
GO:0051865involved_in protein autoubiquitination1IDAHomo_sapiens(9606)Process
GO:0060765involved_in regulation of androgen receptor signaling pathway1IDAHomo_sapiens(9606)Process
GO:0061630enables ubiquitin protein ligase activity1IBAHomo_sapiens(9606)Function

Expression