Welcome to
RBP World!
Description
| Ensembl ID | ENSG00000166949 | Gene ID | 4088 | Accession | 6769 |
| Symbol | SMAD3 | Alias | LDS3;mad3;LDS1C;MADH3;JV15-2;hMAD-3;hSMAD3;HSPC193;HsT17436 | Full Name | SMAD family member 3 |
| Status | Confidence | Length | 131411 bases | Strand | Plus strand |
| Position | 15 : 67063763 - 67195173 | RNA binding domain | N.A. | ||
| Summary | The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. This protein forms a complex with other SMAD proteins and binds DNA, functioning both as a transcription factor and tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3. [provided by RefSeq, May 2022] | ||||
RNA binding domains (RBDs)
| Protein | Domain | Pfam ID | E-value | Domain number |
|---|
RNA binding proteomes (RBPomes)
| Pubmed ID | Full Name | Cell | Author | Time | Doi |
|---|
Literatures on RNA binding capacity
| Pubmed ID | Title | Author | Time | Journal |
|---|---|---|---|---|
| 29036649 | The SMAD3 transcription factor binds complex RNA structures with high affinity. | H Thayne Dickey | 2017-11-16 | Nucleic acids research |
| 27746021 | Direct Regulation of Alternative Splicing by SMAD3 through PCBP1 Is Essential to the Tumor-Promoting Role of TGF-β. | Veenu Tripathi | 2016-11-03 | Molecular cell |
| 33355522 | Healing after COVID-19: are survivors at risk for pulmonary fibrosis? | T Lindsay McDonald | 2021-02-01 | American journal of physiology. Lung cellular and molecular physiology |
| 31533040 | The TGFB2-AS1 lncRNA Regulates TGF-β Signaling by Modulating Corepressor Activity. | Panagiotis Papoutsoglou | 2019-09-17 | Cell reports |
| 23418473 | Effects of TRAP-1-like protein (TLP) gene on collagen synthesis induced by TGF-β/Smad signaling in human dermal fibroblasts. | Xue Wang | 2013-01-01 | PloS one |
| 33520980 | Circ0083429 Regulates Osteoarthritis Progression via the Mir-346/SMAD3 Axis. | Teng Yao | 2020-01-01 | Frontiers in cell and developmental biology |
| 31819495 | Upregulation Of miR-149-3p Suppresses Spinal Chordoma Malignancy By Targeting Smad3. | Jie Yao | 2019-01-01 | OncoTargets and therapy |
| 31426390 | Cardiac Fibroblast to Myofibroblast Phenotype Conversion-An Unexploited Therapeutic Target. | P Michael Czubryt | 2019-08-16 | Journal of cardiovascular development and disease |
| 28197539 | Redirecting RNA splicing by SMAD3 turns TGF-β into a tumor promoter. | Veenu Tripathi | 2017-01-01 | Molecular & cellular oncology |
Transcripts
| Name | Transcript ID | bp | Protein | Translation ID |
|---|---|---|---|---|
| SMAD3-211 | ENST00000559460 | 5887 | 320aa | ENSP00000453082 |
| SMAD3-201 | ENST00000327367 | 6464 | 425aa | ENSP00000332973 |
| SMAD3-215 | ENST00000560424 | 2915 | 462aa | ENSP00000455540 |
| SMAD3-216 | ENST00000679624 | 5838 | 320aa | ENSP00000505445 |
| SMAD3-212 | ENST00000559937 | 579 | No protein | - |
| SMAD3-210 | ENST00000559092 | 584 | 96aa | ENSP00000453788 |
| SMAD3-213 | ENST00000560175 | 542 | 114aa | ENSP00000455095 |
| SMAD3-204 | ENST00000540846 | 1567 | 320aa | ENSP00000437757 |
| SMAD3-209 | ENST00000558894 | 797 | 213aa | ENSP00000458060 |
| SMAD3-202 | ENST00000439724 | 1530 | 381aa | ENSP00000401133 |
| SMAD3-206 | ENST00000558739 | 5993 | 320aa | ENSP00000453684 |
| SMAD3-218 | ENST00000681239 | 5866 | 320aa | ENSP00000505641 |
| SMAD3-203 | ENST00000537194 | 1147 | 230aa | ENSP00000445348 |
| SMAD3-205 | ENST00000558428 | 2000 | 230aa | ENSP00000454165 |
| SMAD3-208 | ENST00000558827 | 1895 | 230aa | ENSP00000452767 |
| SMAD3-214 | ENST00000560402 | 590 | No protein | - |
| SMAD3-217 | ENST00000680689 | 1473 | No protein | - |
| SMAD3-207 | ENST00000558763 | 1957 | No protein | - |
Phenotypes
| ensgID | Trait | pValue | Pubmed ID |
|---|---|---|---|
| 23239 | Body Height | 1.5740000E-005 | - |
| 26498 | Blood Pressure | 4.6760000E-005 | - |
| 26499 | Blood Pressure | 3.3180000E-005 | - |
| 27450 | Cardiovascular Physiological Phenomena | 7.0200000E-005 | - |
| 27471 | Cardiovascular Physiological Phenomena | 7.8360000E-006 | - |
| 27497 | Cardiovascular Physiological Phenomena | 1.8860000E-005 | - |
| 33473 | Blood Pressure | 8.3667233E-005 | - |
| 42574 | Platelet Function Tests | 3.6264200E-005 | - |
| 47400 | Breast Density | 1.1851466E-005 | - |
| 51207 | Child Development Disorders, Pervasive | 3.3224000E-005 | - |
| 64137 | Colitis, Ulcerative | 1E-7 | 26192919 |
| 65019 | Thyroid Neoplasms | 5E-9 | 28195142 |
| 66663 | Hypersensitivity | 4E-8 | 27182965 |
| 68200 | Coronary Disease | 2E-7 | 17634449 |
| 73493 | Inflammatory Bowel Diseases | 3E-20 | 26192919 |
| 77488 | Hypersensitivity | 1E-8 | 23817569 |
| 79044 | Lung Volume Measurements | 3E-7 | 28166213 |
| 79544 | Crohn Disease | 3E-19 | 21102463 |
| 80884 | Crohn Disease | 2E-19 | 28067908 |
| 81806 | Arthritis, Juvenile | 8E-11 | 26301688 |
| 81807 | Autoimmune Diseases | 8E-11 | 26301688 |
| 81808 | Celiac Disease | 8E-11 | 26301688 |
| 81809 | Colitis, Ulcerative | 8E-11 | 26301688 |
| 81810 | Crohn Disease | 8E-11 | 26301688 |
| 81811 | Diabetes Mellitus, Type 1 | 8E-11 | 26301688 |
| 81812 | Lupus Erythematosus, Systemic | 8E-11 | 26301688 |
| 81813 | Psoriasis | 8E-11 | 26301688 |
| 81814 | Spondylitis, Ankylosing | 8E-11 | 26301688 |
| 81815 | Thyroid Diseases | 8E-11 | 26301688 |
| 81816 | Common Variable Immunodeficiency | 8E-11 | 26301688 |
| 82142 | Inflammatory Bowel Diseases | 6E-16 | 23128233 |
| 83268 | Crohn Disease | 4E-20 | 26192919 |
| 84428 | Coronary Artery Disease | 5E-9 | 26343387 |
| 84902 | Thyroid Neoplasms | 3E-9 | 28195142 |
| 86551 | Asthma | 4E-9 | 24388013 |
| 86552 | Rhinitis, Allergic, Seasonal | 4E-9 | 24388013 |
| 88557 | Corneal Topography | 5E-10 | 23291589 |
| 90985 | Asthma | 2E-21 | 27182965 |
| 93884 | Inflammatory Bowel Diseases | 3E-21 | 28067908 |
| 94173 | Body Mass Index | 1E-8 | 25673412 |
| 94174 | Waist Circumference | 1E-8 | 25673412 |
| 99098 | Body Mass Index | 2E-9 | 25673412 |
| 99099 | Waist Circumference | 2E-9 | 25673412 |
| 101987 | Asthma | 4E-9 | 20860503 |
| 102364 | Myocardial Infarction | 1E-7 | 26343387 |
| 103301 | Colitis, Ulcerative | 2E-8 | 28067908 |
GWAS
| ensgID | SNP | Chromosome | Position | Trait | PubmedID | Or or BEAT | EFO ID |
|---|
Protein-Protein Interaction (PPI)
Paralogs
| Ensembl ID | Source | Target | ||||||
|---|---|---|---|---|---|---|---|---|
| Species | Protein ID | Perc_pos | Perc_id | Species | Protein ID | Perc_pos | Perc_id | |
| ENSG00000166949 | homo_sapiens | ENSP00000369154 | 70.2355 | 59.5289 | homo_sapiens | ENSP00000332973 | 77.1765 | 65.4118 |
| ENSG00000166949 | homo_sapiens | ENSP00000305769 | 70.9677 | 61.0753 | homo_sapiens | ENSP00000332973 | 77.6471 | 66.8235 |
| ENSG00000166949 | homo_sapiens | ENSP00000441954 | 72.043 | 61.0753 | homo_sapiens | ENSP00000332973 | 78.8235 | 66.8235 |
| ENSG00000166949 | homo_sapiens | ENSP00000288840 | 36.8952 | 25.6048 | homo_sapiens | ENSP00000332973 | 43.0588 | 29.8824 |
| ENSG00000166949 | homo_sapiens | ENSP00000341551 | 46.3768 | 34.2391 | homo_sapiens | ENSP00000332973 | 60.2353 | 44.4706 |
| ENSG00000166949 | homo_sapiens | ENSP00000262158 | 41.0798 | 25.5869 | homo_sapiens | ENSP00000332973 | 41.1765 | 25.6471 |
| ENSG00000166949 | homo_sapiens | ENSP00000262160 | 87.7944 | 83.7259 | homo_sapiens | ENSP00000332973 | 96.4706 | 92 |
Orthologs
| Ensembl ID | Source | Target | ||||||
|---|---|---|---|---|---|---|---|---|
| Species | Protein ID | Perc_pos | Perc_id | Species | Protein ID | Perc_pos | Perc_id | |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 99.7647 | nomascus_leucogenys | ENSNLEP00000041430 | 100 | 99.7647 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | pan_paniscus | ENSPPAP00000021162 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.9412 | 96.7059 | pongo_abelii | ENSPPYP00000041655 | 91.5556 | 91.3333 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.9412 | 96.4706 | pan_troglodytes | ENSPTRP00000090625 | 93.2127 | 92.7602 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 83.7647 | 83.7647 | gorilla_gorilla | ENSGGOP00000045294 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.5294 | 99.0588 | ornithorhynchus_anatinus | ENSOANP00000053817 | 86.6803 | 86.2705 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 99.5294 | sarcophilus_harrisii | ENSSHAP00000045713 | 99.7653 | 99.2958 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 71.0588 | 70.8235 | notamacropus_eugenii | ENSMEUP00000015235 | 84.8315 | 84.5506 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 76.4706 | 76 | choloepus_hoffmanni | ENSCHOP00000001382 | 92.068 | 91.5014 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | dasypus_novemcinctus | ENSDNOP00000032935 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 88.7059 | 88.2353 | echinops_telfairi | ENSETEP00000002749 | 88.7059 | 88.2353 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.7647 | callithrix_jacchus | ENSCJAP00000003797 | 95.2809 | 95.2809 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.5882 | 98.1176 | cercocebus_atys | ENSCATP00000002316 | 97.669 | 97.2028 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.7647 | macaca_fascicularis | ENSMFAP00000004146 | 99.7647 | 99.7647 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.7647 | macaca_mulatta | ENSMMUP00000041841 | 99.7647 | 99.7647 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.7647 | macaca_nemestrina | ENSMNEP00000018363 | 99.7647 | 99.7647 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.4118 | 96.7059 | papio_anubis | ENSPANP00000050046 | 94.7368 | 94.0503 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.7647 | mandrillus_leucophaeus | ENSMLEP00000016851 | 99.7647 | 99.7647 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 68.4706 | 68.4706 | tursiops_truncatus | ENSTTRP00000002846 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | vulpes_vulpes | ENSVVUP00000019777 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | mus_spretus | MGP_SPRETEiJ_P0091895 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 93.8824 | 93.1765 | equus_asinus | ENSEASP00005051568 | 82.6087 | 81.9876 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | capra_hircus | ENSCHIP00000011729 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 68.7059 | 68.7059 | loxodonta_africana | ENSLAFP00000017777 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | panthera_leo | ENSPLOP00000009612 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 88.4706 | 86.1176 | ailuropoda_melanoleuca | ENSAMEP00000003561 | 69.6296 | 67.7778 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.7647 | bos_indicus_hybrid | ENSBIXP00005000569 | 99.7647 | 99.7647 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 54.1176 | 54.1176 | oryctolagus_cuniculus | ENSOCUP00000027151 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 94.1176 | 93.4118 | equus_caballus | ENSECAP00000039707 | 84.0336 | 83.4034 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | canis_lupus_familiaris | ENSCAFP00845023256 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | panthera_pardus | ENSPPRP00000008496 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 81.4118 | 81.1765 | marmota_marmota_marmota | ENSMMMP00000006703 | 92.2667 | 92 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | balaenoptera_musculus | ENSBMSP00010005299 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 98.8235 | cavia_porcellus | ENSCPOP00000031052 | 99.7647 | 98.8235 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 86.1176 | 84.7059 | felis_catus | ENSFCAP00000034334 | 80.0875 | 78.7746 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | ursus_americanus | ENSUAMP00000026563 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 99.5294 | monodelphis_domestica | ENSMODP00000047929 | 99.7653 | 99.2958 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.5294 | 99.5294 | bison_bison_bison | ENSBBBP00000017171 | 99.5294 | 99.5294 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 68.4706 | 68.4706 | monodon_monoceros | ENSMMNP00015010647 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | sus_scrofa | ENSSSCP00000073915 | 95.2915 | 95.2915 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | microcebus_murinus | ENSMICP00000048645 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 98.8235 | octodon_degus | ENSODEP00000021389 | 99.7647 | 98.8235 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.5294 | jaculus_jaculus | ENSJJAP00000020869 | 99.7647 | 99.5294 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | ovis_aries_rambouillet | ENSOARP00020010865 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 40.4706 | 36 | ursus_maritimus | ENSUMAP00000016415 | 61.4286 | 54.6429 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.7647 | ochotona_princeps | ENSOPRP00000013686 | 99.7647 | 99.7647 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | delphinapterus_leucas | ENSDLEP00000014549 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | physeter_catodon | ENSPCTP00005025310 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | mus_caroli | MGP_CAROLIEiJ_P0088272 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | mus_musculus | ENSMUSP00000034973 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | dipodomys_ordii | ENSDORP00000023202 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 87.5294 | 85.8824 | mustela_putorius_furo | ENSMPUP00000000302 | 89.8551 | 88.1643 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | aotus_nancymaae | ENSANAP00000000216 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 99.7647 | saimiri_boliviensis_boliviensis | ENSSBOP00000007959 | 100 | 99.7647 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.7647 | chlorocebus_sabaeus | ENSCSAP00000009443 | 99.7647 | 99.7647 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 60.2353 | 60.2353 | tupaia_belangeri | ENSTBEP00000003369 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 99.7647 | mesocricetus_auratus | ENSMAUP00000025877 | 100 | 99.7647 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | phocoena_sinus | ENSPSNP00000002978 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 95.2941 | 94.3529 | camelus_dromedarius | ENSCDRP00005004027 | 91.0112 | 90.1124 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.2941 | 98.8235 | carlito_syrichta | ENSTSYP00000029923 | 99.2941 | 98.8235 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 83.7647 | 83.7647 | panthera_tigris_altaica | ENSPTIP00000012611 | 83.7647 | 83.7647 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | rattus_norvegicus | ENSRNOP00000037346 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | prolemur_simus | ENSPSMP00000001694 | 94.4444 | 94.4444 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | microtus_ochrogaster | ENSMOCP00000020974 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.7647 | peromyscus_maniculatus_bairdii | ENSPEMP00000029665 | 99.7647 | 99.7647 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.7647 | bos_mutus | ENSBMUP00000007783 | 99.7647 | 99.7647 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | mus_spicilegus | ENSMSIP00000003996 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 99.7647 | cricetulus_griseus_chok1gshd | ENSCGRP00001012633 | 100 | 99.7647 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 99.7647 | pteropus_vampyrus | ENSPVAP00000002481 | 100 | 99.7647 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 78.5882 | 78.1176 | myotis_lucifugus | ENSMLUP00000001990 | 84.557 | 84.0506 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 99.5294 | vombatus_ursinus | ENSVURP00010022852 | 99.7653 | 99.2958 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 99.7647 | rhinolophus_ferrumequinum | ENSRFEP00010005654 | 100 | 99.7647 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | neovison_vison | ENSNVIP00000020746 | 95.9368 | 95.9368 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.7647 | bos_taurus | ENSBTAP00000016728 | 99.7647 | 99.7647 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 96.4706 | heterocephalus_glaber_female | ENSHGLP00000045433 | 93.4831 | 92.1348 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.7647 | rhinopithecus_bieti | ENSRBIP00000006520 | 88.3333 | 88.3333 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | canis_lupus_dingo | ENSCAFP00020010053 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | sciurus_vulgaris | ENSSVLP00005031764 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 99.5294 | phascolarctos_cinereus | ENSPCIP00000018385 | 99.7653 | 99.2958 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 76.9412 | 76.9412 | procavia_capensis | ENSPCAP00000007581 | 85.1562 | 85.1562 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | nannospalax_galili | ENSNGAP00000025649 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.9412 | 96.4706 | bos_grunniens | ENSBGRP00000038217 | 89.3709 | 88.9371 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.0588 | chinchilla_lanigera | ENSCLAP00000007147 | 99.7647 | 99.0588 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | cervus_hanglu_yarkandensis | ENSCHYP00000017315 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | catagonus_wagneri | ENSCWAP00000019600 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | ictidomys_tridecemlineatus | ENSSTOP00000009229 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | otolemur_garnettii | ENSOGAP00000012739 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | cebus_imitator | ENSCCAP00000006038 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.4118 | 97.4118 | urocitellus_parryii | ENSUPAP00010022706 | 89.0323 | 89.0323 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 99.7647 | moschus_moschiferus | ENSMMSP00000001866 | 100 | 99.7647 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.7647 | rhinopithecus_roxellana | ENSRROP00000006108 | 88.3333 | 88.3333 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | mus_pahari | MGP_PahariEiJ_P0023918 | 100 | 100 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 100 | propithecus_coquereli | ENSPCOP00000021905 | 95.9368 | 95.9368 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 85.1765 | 74.3529 | ciona_intestinalis | ENSCINP00000012794 | 84.9765 | 74.1784 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 55.7647 | 52.2353 | petromyzon_marinus | ENSPMAP00000005913 | 90.1141 | 84.4106 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 28.2353 | 26.1176 | petromyzon_marinus | ENSPMAP00000004626 | 93.75 | 86.7188 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 94.5882 | 88.9412 | petromyzon_marinus | ENSPMAP00000000544 | 92.6267 | 87.0968 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 41.1765 | 36.7059 | eptatretus_burgeri | ENSEBUP00000007865 | 78.125 | 69.6429 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 92 | 84.4706 | eptatretus_burgeri | ENSEBUP00000011107 | 91.784 | 84.2723 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 92.2353 | 84.4706 | eptatretus_burgeri | ENSEBUP00000024740 | 58.5075 | 53.5821 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 66.3529 | 63.5294 | callorhinchus_milii | ENSCMIP00000035482 | 98.2578 | 94.0767 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 83.5294 | 82.1176 | latimeria_chalumnae | ENSLACP00000011989 | 99.162 | 97.486 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.8235 | 97.1765 | lepisosteus_oculatus | ENSLOCP00000017141 | 98.3607 | 96.7213 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.3529 | 95.2941 | clupea_harengus | ENSCHAP00000051851 | 93.722 | 90.8072 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.6471 | 95.2941 | clupea_harengus | ENSCHAP00000053832 | 94.3182 | 92.0455 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.9412 | 93.1765 | danio_rerio | ENSDARP00000043454 | 97.3995 | 93.617 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.5882 | 96.9412 | danio_rerio | ENSDARP00000045373 | 98.5882 | 96.9412 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.1765 | 93.6471 | carassius_auratus | ENSCARP00000031415 | 91.7778 | 88.4444 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.2353 | 92.7059 | carassius_auratus | ENSCARP00000111271 | 96.9194 | 93.3649 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.3529 | 96.4706 | carassius_auratus | ENSCARP00000101101 | 98.1221 | 96.2441 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.5882 | 96.9412 | carassius_auratus | ENSCARP00000122668 | 93.5268 | 91.9643 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.1176 | 96 | carassius_auratus | ENSCARP00000077739 | 92.2566 | 90.2655 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.1176 | 95.5294 | astyanax_mexicanus | ENSAMXP00000031297 | 98.3491 | 95.7547 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.5882 | 96.7059 | astyanax_mexicanus | ENSAMXP00000046514 | 98.5882 | 96.7059 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.4706 | 94.3529 | ictalurus_punctatus | ENSIPUP00000028880 | 96.4706 | 94.3529 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.4706 | 93.4118 | ictalurus_punctatus | ENSIPUP00000032239 | 96.6981 | 93.6321 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.9412 | 94.8235 | esox_lucius | ENSELUP00000040560 | 91.9643 | 89.9554 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.4706 | 93.4118 | esox_lucius | ENSELUP00000051951 | 91.1111 | 88.2222 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 93.6471 | 90.3529 | electrophorus_electricus | ENSEEEP00000019850 | 89.038 | 85.906 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.8235 | 96.7059 | electrophorus_electricus | ENSEEEP00000042768 | 98.8235 | 96.7059 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.6471 | 95.7647 | oncorhynchus_kisutch | ENSOKIP00005071522 | 88.4861 | 86.7804 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 90.1176 | 87.5294 | oncorhynchus_kisutch | ENSOKIP00005057304 | 92.5121 | 89.8551 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 92.9412 | 89.6471 | oncorhynchus_mykiss | ENSOMYP00000116943 | 89.9772 | 86.7882 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.6471 | 95.7647 | oncorhynchus_mykiss | ENSOMYP00000005438 | 92.0177 | 90.2439 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.6471 | 95.7647 | oncorhynchus_mykiss | ENSOMYP00000120526 | 92.0177 | 90.2439 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 91.0588 | 87.7647 | salmo_salar | ENSSSAP00000181916 | 88.7615 | 85.5505 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 93.4118 | 90.3529 | salmo_salar | ENSSSAP00000178246 | 88.4187 | 85.5234 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.6471 | 95.5294 | salmo_salar | ENSSSAP00000137320 | 93.0493 | 91.0314 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 77.6471 | 72.4706 | salmo_salar | ENSSSAP00000090009 | 81.0811 | 75.6757 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.4118 | 95.2941 | salmo_trutta | ENSSTUP00000032342 | 93.2432 | 91.2162 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 93.4118 | 89.6471 | salmo_trutta | ENSSTUP00000032177 | 88.2222 | 84.6667 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 19.5294 | 18.1176 | salmo_trutta | ENSSTUP00000068694 | 83 | 77 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 94.3529 | 92 | gadus_morhua | ENSGMOP00000028032 | 93.6916 | 91.3551 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.6471 | 95.5294 | gadus_morhua | ENSGMOP00000008949 | 95.4023 | 93.3333 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 95.7647 | fundulus_heteroclitus | ENSFHEP00000002244 | 97.4239 | 95.3162 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96 | 92.2353 | fundulus_heteroclitus | ENSFHEP00000034181 | 96 | 92.2353 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 95.7647 | poecilia_reticulata | ENSPREP00000012114 | 97.8824 | 95.7647 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.2353 | 91.2941 | poecilia_reticulata | ENSPREP00000015844 | 96.2353 | 91.2941 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.7059 | 92 | xiphophorus_maculatus | ENSXMAP00000003571 | 96.7059 | 92 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 95.5294 | xiphophorus_maculatus | ENSXMAP00000041069 | 97.8824 | 95.5294 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.6471 | 95.5294 | oryzias_latipes | ENSORLP00000002748 | 97.6471 | 95.5294 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 94.3529 | 88.9412 | oryzias_latipes | ENSORLP00000008548 | 94.3529 | 88.9412 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 93.6471 | 90.5882 | cyclopterus_lumpus | ENSCLMP00005042684 | 91.2844 | 88.3027 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.6471 | 95.7647 | cyclopterus_lumpus | ENSCLMP00005045004 | 96.5116 | 94.6512 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 96.2353 | oreochromis_niloticus | ENSONIP00000071836 | 97.8824 | 96.2353 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.4706 | 92.7059 | oreochromis_niloticus | ENSONIP00000019456 | 91.5179 | 87.9464 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 80.9412 | 77.8824 | haplochromis_burtoni | ENSHBUP00000015708 | 91.7333 | 88.2667 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 15.7647 | 15.0588 | haplochromis_burtoni | ENSHBUP00000028658 | 98.5294 | 94.1176 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 96.2353 | haplochromis_burtoni | ENSHBUP00000028352 | 97.8824 | 96.2353 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 96.2353 | astatotilapia_calliptera | ENSACLP00000023954 | 97.8824 | 96.2353 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.7059 | 92.9412 | astatotilapia_calliptera | ENSACLP00000022096 | 96.7059 | 92.9412 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 96 | sparus_aurata | ENSSAUP00010002596 | 92.6503 | 90.8686 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.6471 | 94.1176 | sparus_aurata | ENSSAUP00010026975 | 93.0493 | 89.6861 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 94.8235 | lates_calcarifer | ENSLCAP00010026768 | 92.6503 | 89.755 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 95.7647 | lates_calcarifer | ENSLCAP00010002040 | 92.0354 | 90.0443 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.8235 | 95.7647 | xenopus_tropicalis | ENSXETP00000017041 | 84.6774 | 82.0564 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 99.2941 | chrysemys_picta_bellii | ENSCPBP00000036845 | 99.7653 | 99.061 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 86.1176 | 85.1765 | sphenodon_punctatus | ENSSPUP00000017396 | 95.3125 | 94.2708 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.5294 | 98.5882 | crocodylus_porosus | ENSCPRP00005000936 | 99.2958 | 98.3568 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 76.9412 | 74.1176 | laticauda_laticaudata | ENSLLTP00000005968 | 89.589 | 86.3014 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.0588 | 97.6471 | notechis_scutatus | ENSNSUP00000004986 | 94.6067 | 93.2584 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.0588 | 97.6471 | pseudonaja_textilis | ENSPTXP00000022459 | 98.8263 | 97.4178 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.0588 | anas_platyrhynchos_platyrhynchos | ENSAPLP00000006649 | 99.5305 | 98.8263 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.0588 | gallus_gallus | ENSGALP00010026036 | 94.0133 | 93.3481 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.0588 | meleagris_gallopavo | ENSMGAP00000010220 | 99.5305 | 98.8263 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 78.5882 | 74.1176 | serinus_canaria | ENSSCAP00000014146 | 77.4942 | 73.0858 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.2941 | parus_major | ENSPMJP00000013058 | 99.5305 | 99.061 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 66.8235 | 62.1176 | anolis_carolinensis | ENSACAP00000009794 | 82.3188 | 76.5217 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 96.2353 | neolamprologus_brichardi | ENSNBRP00000028846 | 97.8824 | 96.2353 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.4706 | 92.7059 | neolamprologus_brichardi | ENSNBRP00000020528 | 96.4706 | 92.7059 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.0588 | 97.6471 | naja_naja | ENSNNAP00000016746 | 98.8263 | 97.4178 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 94.5882 | 91.5294 | podarcis_muralis | ENSPMRP00000022512 | 90.5405 | 87.6126 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 66.8235 | 52.7059 | podarcis_muralis | ENSPMRP00000030210 | 62.0087 | 48.9083 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 88.2353 | 86.1176 | geospiza_fortis | ENSGFOP00000017488 | 95.6633 | 93.3673 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 94.8235 | 92.2353 | taeniopygia_guttata | ENSTGUP00000025934 | 90.5618 | 88.0899 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.1176 | 94.8235 | erpetoichthys_calabaricus | ENSECRP00000028069 | 92.053 | 88.9625 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 96 | kryptolebias_marmoratus | ENSKMAP00000015782 | 97.8824 | 96 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 95.5294 | 91.5294 | kryptolebias_marmoratus | ENSKMAP00000026576 | 95.5294 | 91.5294 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.0588 | 98.3529 | salvator_merianae | ENSSMRP00000028049 | 98.8263 | 98.1221 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 94.3529 | 88.2353 | oryzias_javanicus | ENSOJAP00000025545 | 89.5089 | 83.7054 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.6471 | 95.7647 | oryzias_javanicus | ENSOJAP00000041235 | 92.0177 | 90.2439 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.4118 | 93.6471 | amphilophus_citrinellus | ENSACIP00000005135 | 97.4118 | 93.6471 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 96.2353 | amphilophus_citrinellus | ENSACIP00000021293 | 97.8824 | 96.2353 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.1176 | 94.8235 | dicentrarchus_labrax | ENSDLAP00005011356 | 93.2886 | 90.1566 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.1176 | 96.2353 | dicentrarchus_labrax | ENSDLAP00005027627 | 92.6667 | 90.8889 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 87.5294 | 85.4118 | amphiprion_percula | ENSAPEP00000000717 | 96.124 | 93.7984 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 94.5882 | amphiprion_percula | ENSAPEP00000029729 | 97.8824 | 94.5882 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.6471 | 95.5294 | oryzias_sinensis | ENSOSIP00000010143 | 96.2877 | 94.1995 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 92.2353 | 87.5294 | oryzias_sinensis | ENSOSIP00000041928 | 89.4977 | 84.9315 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 84 | 83.5294 | pelodiscus_sinensis | ENSPSIP00000011835 | 99.7207 | 99.162 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 99.2941 | gopherus_evgoodei | ENSGEVP00005007202 | 99.7653 | 99.061 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 89.6471 | 87.0588 | chelonoidis_abingdonii | ENSCABP00000009275 | 86.5909 | 84.0909 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.6471 | 94.5882 | seriola_dumerili | ENSSDUP00000010894 | 97.6471 | 94.5882 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.1176 | 96 | seriola_dumerili | ENSSDUP00000023503 | 98.1176 | 96 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.4118 | 94.3529 | cottoperca_gobio | ENSCGOP00000033357 | 92.2049 | 89.3096 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 96 | cottoperca_gobio | ENSCGOP00000023802 | 94.3311 | 92.517 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 87.5294 | 85.8824 | struthio_camelus_australis | ENSSCUP00000003908 | 90.9535 | 89.2421 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.0588 | anser_brachyrhynchus | ENSABRP00000009494 | 99.5305 | 98.8263 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.1765 | 93.6471 | gasterosteus_aculeatus | ENSGACP00000006754 | 96.9484 | 93.4272 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 76.7059 | 71.2941 | gasterosteus_aculeatus | ENSGACP00000022299 | 77.619 | 72.1429 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.6471 | 95.0588 | cynoglossus_semilaevis | ENSCSEP00000019724 | 97.6471 | 95.0588 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.9412 | 93.8824 | cynoglossus_semilaevis | ENSCSEP00000011015 | 96.9412 | 93.8824 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.4706 | 92 | poecilia_formosa | ENSPFOP00000008825 | 96.4706 | 92 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 95.7647 | poecilia_formosa | ENSPFOP00000006399 | 97.6526 | 95.5399 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.5882 | 97.1765 | myripristis_murdjan | ENSMMDP00005028536 | 98.5882 | 97.1765 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.3529 | 95.2941 | myripristis_murdjan | ENSMMDP00005019562 | 98.3529 | 95.2941 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.1176 | 96.2353 | sander_lucioperca | ENSSLUP00000043189 | 98.1176 | 96.2353 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.1765 | 93.8824 | sander_lucioperca | ENSSLUP00000000620 | 97.1765 | 93.8824 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.0588 | strigops_habroptila | ENSSHBP00005000822 | 99.5305 | 98.8263 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.1176 | 96.2353 | amphiprion_ocellaris | ENSAOCP00000005512 | 98.1176 | 96.2353 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 94.5882 | amphiprion_ocellaris | ENSAOCP00000000790 | 97.8824 | 94.5882 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 100 | 99.2941 | terrapene_carolina_triunguis | ENSTMTP00000011620 | 99.7653 | 99.061 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 25.1765 | 21.1765 | hucho_hucho | ENSHHUP00000062697 | 75.8865 | 63.8298 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 16.9412 | 15.7647 | hucho_hucho | ENSHHUP00000069182 | 94.7368 | 88.1579 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.1176 | 96 | betta_splendens | ENSBSLP00000031252 | 92.2566 | 90.2655 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.4706 | 93.4118 | betta_splendens | ENSBSLP00000033924 | 94.47 | 91.4747 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.5882 | 96.9412 | pygocentrus_nattereri | ENSPNAP00000028729 | 93.1111 | 91.5556 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.1176 | 95.7647 | pygocentrus_nattereri | ENSPNAP00000028695 | 98.3491 | 95.9906 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.1176 | 96.2353 | anabas_testudineus | ENSATEP00000026885 | 98.1176 | 96.2353 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 94.5882 | anabas_testudineus | ENSATEP00000014111 | 93.9052 | 90.7449 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 84.7059 | 73.6471 | ciona_savignyi | ENSCSAVP00000007961 | 80 | 69.5556 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 74.8235 | 61.1765 | ciona_savignyi | ENSCSAVP00000008093 | 63.6 | 52 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.6471 | 94.5882 | seriola_lalandi_dorsalis | ENSSLDP00000030572 | 97.6471 | 94.5882 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.1176 | 96 | seriola_lalandi_dorsalis | ENSSLDP00000013131 | 98.1176 | 96 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 96 | labrus_bergylta | ENSLBEP00000024765 | 97.8824 | 96 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.9412 | 94.1176 | labrus_bergylta | ENSLBEP00000023277 | 96.9412 | 94.1176 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 81.1765 | 78.5882 | labrus_bergylta | ENSLBEP00000019944 | 92.9919 | 90.027 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 92.7059 | 88.9412 | pundamilia_nyererei | ENSPNYP00000019172 | 94.9398 | 91.0843 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 96.2353 | pundamilia_nyererei | ENSPNYP00000010407 | 97.8824 | 96.2353 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.4706 | 92.7059 | mastacembelus_armatus | ENSMAMP00000043211 | 91.7226 | 88.1432 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.1176 | 96.2353 | mastacembelus_armatus | ENSMAMP00000043975 | 94.9886 | 93.1663 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.3529 | 96.7059 | stegastes_partitus | ENSSPAP00000025771 | 98.3529 | 96.7059 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 94.5882 | stegastes_partitus | ENSSPAP00000025327 | 97.8824 | 94.5882 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 15.7647 | 15.5294 | oncorhynchus_tshawytscha | ENSOTSP00005069612 | 98.5294 | 97.0588 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 15.7647 | 15.5294 | oncorhynchus_tshawytscha | ENSOTSP00005036895 | 94.3662 | 92.9577 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.1176 | 96.4706 | acanthochromis_polyacanthus | ENSAPOP00000029807 | 98.1176 | 96.4706 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 94.5882 | acanthochromis_polyacanthus | ENSAPOP00000006820 | 97.8824 | 94.5882 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.7647 | 99.0588 | aquila_chrysaetos_chrysaetos | ENSACCP00020000756 | 99.5305 | 98.8263 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 15.7647 | 15.5294 | nothobranchius_furzeri | ENSNFUP00015021476 | 98.5294 | 97.0588 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 64.4706 | 61.4118 | nothobranchius_furzeri | ENSNFUP00015047404 | 94.8097 | 90.3114 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 91.0588 | 85.1765 | nothobranchius_furzeri | ENSNFUP00015016718 | 80.9623 | 75.7322 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.4706 | 91.2941 | cyprinodon_variegatus | ENSCVAP00000024017 | 96.4706 | 91.2941 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 95.5294 | cyprinodon_variegatus | ENSCVAP00000025010 | 97.8824 | 95.5294 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 95.7647 | 92.4706 | denticeps_clupeoides | ENSDCDP00000033647 | 90.4444 | 87.3333 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 90.1176 | 83.5294 | denticeps_clupeoides | ENSDCDP00000013281 | 61.5756 | 57.074 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 94.1176 | 90.3529 | denticeps_clupeoides | ENSDCDP00000013273 | 92.3788 | 88.6836 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.6471 | 94.5882 | larimichthys_crocea | ENSLCRP00005022189 | 93.4685 | 90.5405 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 96 | larimichthys_crocea | ENSLCRP00005013590 | 92.2395 | 90.4656 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 95.5294 | 89.8824 | takifugu_rubripes | ENSTRUP00000062498 | 92.0635 | 86.6213 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 87.5294 | 83.2941 | takifugu_rubripes | ENSTRUP00000069793 | 81.9383 | 77.9736 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.5294 | 99.0588 | ficedula_albicollis | ENSFALP00000018844 | 99.2958 | 98.8263 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.3529 | 96.7059 | hippocampus_comes | ENSHCOP00000021937 | 98.3529 | 96.7059 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.4118 | 93.8824 | hippocampus_comes | ENSHCOP00000012065 | 97.4118 | 93.8824 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.5882 | 97.1765 | cyprinus_carpio_carpio | ENSCCRP00000155183 | 98.5882 | 97.1765 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.3529 | 96.7059 | cyprinus_carpio_carpio | ENSCCRP00000132991 | 93.3036 | 91.7411 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.1765 | 93.6471 | cyprinus_carpio_carpio | ENSCCRP00000128787 | 93.4389 | 90.0452 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 95.7647 | 92.2353 | cyprinus_carpio_carpio | ENSCCRP00000026253 | 96.2175 | 92.6714 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 99.5294 | 98.8235 | coturnix_japonica | ENSCJPP00005026987 | 97.0183 | 96.3303 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 95.7647 | poecilia_latipinna | ENSPLAP00000008877 | 97.8824 | 95.7647 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.4706 | 92.2353 | poecilia_latipinna | ENSPLAP00000005904 | 96.4706 | 92.2353 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.5882 | 97.1765 | sinocyclocheilus_grahami | ENSSGRP00000003942 | 98.5882 | 97.1765 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 15.7647 | 15.2941 | sinocyclocheilus_grahami | ENSSGRP00000108174 | 98.5294 | 95.5882 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 96.7059 | 93.1765 | sinocyclocheilus_grahami | ENSSGRP00000049287 | 90.7285 | 87.4172 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.5882 | 96.9412 | sinocyclocheilus_grahami | ENSSGRP00000070223 | 95.4442 | 93.8497 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 92.7059 | 88.9412 | maylandia_zebra | ENSMZEP00005030447 | 94.9398 | 91.0843 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 96.2353 | maylandia_zebra | ENSMZEP00005016483 | 97.8824 | 96.2353 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.1765 | 95.0588 | tetraodon_nigroviridis | ENSTNIP00000012419 | 97.1765 | 95.0588 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 94.3529 | 88.4706 | tetraodon_nigroviridis | ENSTNIP00000011268 | 94.1315 | 88.2629 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.1765 | 94.3529 | paramormyrops_kingsleyae | ENSPKIP00000037749 | 93.6508 | 90.9297 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 98.1176 | 96 | scleropages_formosus | ENSSFOP00015050545 | 91.2473 | 89.2779 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 95.0588 | leptobrachium_leishanense | ENSLLEP00000015219 | 92.8571 | 90.1786 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 95.7647 | scophthalmus_maximus | ENSSMAP00000040284 | 91.4286 | 89.4505 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.4118 | 93.6471 | scophthalmus_maximus | ENSSMAP00000023623 | 93.2432 | 89.6396 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 97.8824 | 96 | oryzias_melastigma | ENSOMEP00000007833 | 97.8824 | 96 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 81.4118 | 71.5294 | oryzias_melastigma | ENSOMEP00000018305 | 80.6527 | 70.8625 |
| ENSG00000166949 | homo_sapiens | ENSP00000332973 | 14.3529 | 13.6471 | oryzias_melastigma | ENSOMEP00000032745 | 96.8254 | 92.0635 |
Gene Ontology
| Go ID | Go term | No. evidence | Entries | Species | Category |
|---|---|---|---|---|---|
| GO:0000122 | involved_in negative regulation of transcription by RNA polymerase II | 2 | IDA,IMP | Homo_sapiens(9606) | Process |
| GO:0000785 | part_of chromatin | 2 | IDA,ISA | Homo_sapiens(9606) | Component |
| GO:0000976 | enables transcription cis-regulatory region binding | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0000978 | enables RNA polymerase II cis-regulatory region sequence-specific DNA binding | 2 | IBA,IDA | Homo_sapiens(9606) | Function |
| GO:0000981 | enables DNA-binding transcription factor activity, RNA polymerase II-specific | 3 | IBA,IDA,ISA | Homo_sapiens(9606) | Function |
| GO:0000987 | enables cis-regulatory region sequence-specific DNA binding | 3 | IC,IDA,IMP | Homo_sapiens(9606) | Function |
| GO:0001217 | enables DNA-binding transcription repressor activity | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0001223 | enables transcription coactivator binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0001228 | enables DNA-binding transcription activator activity, RNA polymerase II-specific | 3 | IDA,IMP,ISS | Homo_sapiens(9606) | Function |
| GO:0001657 | involved_in ureteric bud development | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0001666 | involved_in response to hypoxia | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0001701 | involved_in in utero embryonic development | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0001707 | involved_in mesoderm formation | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0001756 | involved_in somitogenesis | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0001889 | involved_in liver development | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0001947 | involved_in heart looping | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0002076 | involved_in osteoblast development | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0002520 | involved_in immune system development | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0003677 | enables DNA binding | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0003700 | contributes_to DNA-binding transcription factor activity | 3 | IDA,IMP | Homo_sapiens(9606) | Function |
| GO:0005160 | enables transforming growth factor beta receptor binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0005515 | enables protein binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0005518 | enables collagen binding | 1 | IEA | Homo_sapiens(9606) | Function |
| GO:0005634 | located_in nucleus | 2 | IDA,IGI | Homo_sapiens(9606) | Component |
| GO:0005637 | located_in nuclear inner membrane | 1 | IDA | Homo_sapiens(9606) | Component |
| GO:0005654 | located_in nucleoplasm | 2 | IDA,TAS | Homo_sapiens(9606) | Component |
| GO:0005667 | part_of transcription regulator complex | 2 | IDA,IPI | Homo_sapiens(9606) | Component |
| GO:0005737 | located_in cytoplasm | 1 | IDA | Homo_sapiens(9606) | Component |
| GO:0005829 | located_in cytosol | 3 | IDA,IGI,TAS | Homo_sapiens(9606) | Component |
| GO:0005886 | located_in plasma membrane | 1 | IEA | Homo_sapiens(9606) | Component |
| GO:0006355 | involved_in regulation of DNA-templated transcription | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0006357 | involved_in regulation of transcription by RNA polymerase II | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0006919 | involved_in activation of cysteine-type endopeptidase activity involved in apoptotic process | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0006955 | involved_in immune response | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0007179 | involved_in transforming growth factor beta receptor signaling pathway | 2 | IBA,IDA | Homo_sapiens(9606) | Process |
| GO:0007254 | involved_in JNK cascade | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0007492 | involved_in endoderm development | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0008013 | enables beta-catenin binding | 1 | IEA | Homo_sapiens(9606) | Function |
| GO:0008270 | enables zinc ion binding | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0008285 | involved_in negative regulation of cell population proliferation | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0009653 | involved_in anatomical structure morphogenesis | 1 | IBA | Homo_sapiens(9606) | Process |
| GO:0009880 | involved_in embryonic pattern specification | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0010628 | involved_in positive regulation of gene expression | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0010629 | acts_upstream_of negative regulation of gene expression | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0010694 | involved_in positive regulation of alkaline phosphatase activity | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0010718 | involved_in positive regulation of epithelial to mesenchymal transition | 2 | IDA,IMP | Homo_sapiens(9606) | Process |
| GO:0016202 | involved_in regulation of striated muscle tissue development | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0016922 | enables nuclear receptor binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0017015 | involved_in regulation of transforming growth factor beta receptor signaling pathway | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0017151 | enables DEAD/H-box RNA helicase binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0019901 | enables protein kinase binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0019902 | enables phosphatase binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0023019 | involved_in signal transduction involved in regulation of gene expression | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0030154 | involved_in cell differentiation | 1 | IBA | Homo_sapiens(9606) | Process |
| GO:0030308 | involved_in negative regulation of cell growth | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0030325 | involved_in adrenal gland development | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0030335 | involved_in positive regulation of cell migration | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0030501 | involved_in positive regulation of bone mineralization | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0030878 | involved_in thyroid gland development | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0031053 | involved_in primary miRNA processing | 1 | TAS | Homo_sapiens(9606) | Process |
| GO:0031490 | enables chromatin DNA binding | 1 | IEA | Homo_sapiens(9606) | Function |
| GO:0031625 | enables ubiquitin protein ligase binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0031962 | enables nuclear mineralocorticoid receptor binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0032332 | involved_in positive regulation of chondrocyte differentiation | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0032731 | involved_in positive regulation of interleukin-1 beta production | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0032810 | enables sterol response element binding | 1 | IGI | Homo_sapiens(9606) | Function |
| GO:0032909 | involved_in regulation of transforming growth factor beta2 production | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0032916 | involved_in positive regulation of transforming growth factor beta3 production | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0032924 | involved_in activin receptor signaling pathway | 2 | IBA,IMP | Homo_sapiens(9606) | Process |
| GO:0033689 | involved_in negative regulation of osteoblast proliferation | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0035259 | enables nuclear glucocorticoid receptor binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0038092 | involved_in nodal signaling pathway | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0042060 | involved_in wound healing | 1 | TAS | Homo_sapiens(9606) | Process |
| GO:0042110 | involved_in T cell activation | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0042177 | involved_in negative regulation of protein catabolic process | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0042307 | involved_in positive regulation of protein import into nucleus | 1 | NAS | Homo_sapiens(9606) | Process |
| GO:0042802 | enables identical protein binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0042803 | enables protein homodimerization activity | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0043066 | involved_in negative regulation of apoptotic process | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0043130 | enables ubiquitin binding | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0043235 | part_of receptor complex | 1 | IMP | Homo_sapiens(9606) | Component |
| GO:0043425 | enables bHLH transcription factor binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0043565 | enables sequence-specific DNA binding | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0045216 | involved_in cell-cell junction organization | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0045429 | involved_in positive regulation of nitric oxide biosynthetic process | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0045599 | involved_in negative regulation of fat cell differentiation | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0045668 | involved_in negative regulation of osteoblast differentiation | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0045893 | involved_in positive regulation of DNA-templated transcription | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0045944 | involved_in positive regulation of transcription by RNA polymerase II | 3 | IBA,IDA,IMP | Homo_sapiens(9606) | Process |
| GO:0048340 | involved_in paraxial mesoderm morphogenesis | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0048589 | involved_in developmental growth | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0048617 | involved_in embryonic foregut morphogenesis | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0048701 | involved_in embryonic cranial skeleton morphogenesis | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0050678 | involved_in regulation of epithelial cell proliferation | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0050728 | involved_in negative regulation of inflammatory response | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0050776 | involved_in regulation of immune response | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0050821 | involved_in protein stabilization | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0050927 | involved_in positive regulation of positive chemotaxis | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0051091 | involved_in positive regulation of DNA-binding transcription factor activity | 1 | NAS | Homo_sapiens(9606) | Process |
| GO:0051098 | involved_in regulation of binding | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0051481 | involved_in negative regulation of cytosolic calcium ion concentration | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0051496 | involved_in positive regulation of stress fiber assembly | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0051894 | involved_in positive regulation of focal adhesion assembly | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0060039 | involved_in pericardium development | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0060290 | involved_in transdifferentiation | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0060395 | involved_in SMAD protein signal transduction | 2 | IBA,NAS | Homo_sapiens(9606) | Process |
| GO:0061045 | involved_in negative regulation of wound healing | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0061629 | enables RNA polymerase II-specific DNA-binding transcription factor binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0061767 | involved_in negative regulation of lung blood pressure | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0070306 | involved_in lens fiber cell differentiation | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0070410 | enables co-SMAD binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0070411 | enables I-SMAD binding | 1 | IBA | Homo_sapiens(9606) | Function |
| GO:0070412 | enables R-SMAD binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0071141 | part_of SMAD protein complex | 1 | IDA | Homo_sapiens(9606) | Component |
| GO:0071144 | part_of heteromeric SMAD protein complex | 3 | IBA,IDA,IPI | Homo_sapiens(9606) | Component |
| GO:0071560 | involved_in cellular response to transforming growth factor beta stimulus | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0090263 | involved_in positive regulation of canonical Wnt signaling pathway | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0097191 | involved_in extrinsic apoptotic signaling pathway | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0097296 | involved_in activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0098586 | involved_in cellular response to virus | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0140297 | enables DNA-binding transcription factor binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:1901203 | involved_in positive regulation of extracellular matrix assembly | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:1902893 | involved_in regulation of miRNA transcription | 1 | IC | Homo_sapiens(9606) | Process |
| GO:1902894 | involved_in negative regulation of miRNA transcription | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:1902895 | involved_in positive regulation of miRNA transcription | 2 | IDA,IMP | Homo_sapiens(9606) | Process |
| GO:1903243 | involved_in negative regulation of cardiac muscle hypertrophy in response to stress | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:1990841 | enables promoter-specific chromatin binding | 1 | IEA | Homo_sapiens(9606) | Function |