RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	E3 ligase
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000162722	Gene ID	25893	Accession	24150
Symbol	TRIM58	Alias	BIA2	Full Name	tripartite motif containing 58
Status	Confidence	Length	22952 bases	Strand	Plus strand
Position	1 : 247857187 - 247880138	RNA binding domain	SPRY
Summary	Predicted to enable dynein heavy chain binding activity; dynein intermediate chain binding activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including positive regulation of erythrocyte enucleation; protein ubiquitination; and regulation of nuclear migration along microtubule. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000355437	SPRY	PF00622	1.2e-14	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
TRIM58-201	ENST00000366481	5170	486aa	ENSP00000355437

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
26594	Antihypertensive Agents	5.3640000E-005	-
70936	Erythrocyte Count	1E-9	28017375
93802	Erythrocyte Count	5E-10	23222517
94831	Erythrocyte Count	3E-14	28017375
95436	Platelet Count	6E-9	22139419
102904	Fatty Acids	5E-11	25500335
102905	Oleic Acid	5E-11	25500335
106803	Erythrocyte Count	2E-8	20139978

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000209	involved_in protein polyubiquitination	1	IBA	Homo_sapiens(9606)	Process
GO:0003674	enables molecular_function	1	ND	Homo_sapiens(9606)	Function
GO:0005654	is_active_in nucleoplasm	1	IBA	Homo_sapiens(9606)	Component
GO:0005737	is_active_in cytoplasm	1	IBA	Homo_sapiens(9606)	Component
GO:0005829	is_active_in cytosol	1	IBA	Homo_sapiens(9606)	Component
GO:0006511	involved_in ubiquitin-dependent protein catabolic process	1	IEA	Homo_sapiens(9606)	Process
GO:0008150	involved_in biological_process	1	ND	Homo_sapiens(9606)	Process
GO:0008270	enables zinc ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0010508	involved_in positive regulation of autophagy	1	IBA	Homo_sapiens(9606)	Process
GO:0019901	enables protein kinase binding	1	IBA	Homo_sapiens(9606)	Function
GO:0032880	involved_in regulation of protein localization	1	IBA	Homo_sapiens(9606)	Process
GO:0042803	enables protein homodimerization activity	1	IBA	Homo_sapiens(9606)	Function
GO:0043123	involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling	1	IBA	Homo_sapiens(9606)	Process
GO:0045087	involved_in innate immune response	1	IBA	Homo_sapiens(9606)	Process
GO:0045504	enables dynein heavy chain binding	1	IEA	Homo_sapiens(9606)	Function
GO:0045505	enables dynein intermediate chain binding	1	IEA	Homo_sapiens(9606)	Function
GO:0046596	involved_in regulation of viral entry into host cell	1	IBA	Homo_sapiens(9606)	Process
GO:0051092	involved_in positive regulation of NF-kappaB transcription factor activity	1	IBA	Homo_sapiens(9606)	Process
GO:0051865	involved_in protein autoubiquitination	1	IEA	Homo_sapiens(9606)	Process
GO:0061630	enables ubiquitin protein ligase activity	1	IBA	Homo_sapiens(9606)	Function
GO:0061931	involved_in positive regulation of erythrocyte enucleation	1	IEA	Homo_sapiens(9606)	Process
GO:1902838	involved_in regulation of nuclear migration along microtubule	1	IEA	Homo_sapiens(9606)	Process