RBP Type
Non-canonical_RBPs
Diseases
Drug
N.A.
Main interacting RNAs
N.A.
Moonlighting functions
N.A.
Localizations
Stress granucle Nucleoli
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000160213 Gene ID
1476 Accession
2482
Symbol
CSTB
Alias
PME;ULD;CST6;EPM1;STFB;CPI-B;EPM1A
Full Name
cystatin B
Status
Confidence
Length
3808 bases
Strand
Minus strand
Position
21 : 43772511 - 43776318
RNA binding domain
N.A.
Summary
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). One type of mutation responsible for EPM1 is the expansion in the promoter region of this gene of a CCCCGCCCCGCG repeat from 2-3 copies to 30-78 copies. [provided by RefSeq, Jul 2016]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
30384423 In Silico Analysis of Missense Mutations as a First Step in Functional Studies: Examples from Two Sphingolipidoses.
Joana Ana Duarte
2018-10-31
International journal of molecular sciences
Name
Transcript ID
bp
Protein
Translation ID
CSTB-203
ENST00000639959
1855
54aa
ENSP00000492123
CSTB-204
ENST00000640406
2354
83aa
ENSP00000492672
CSTB-202
ENST00000480147
3744
No protein
-
CSTB-205
ENST00000675996
1258
No protein
-
CSTB-201
ENST00000291568
588
98aa
ENSP00000291568
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000160213 homo_sapiens ENSP00000264474 71.4286 53.0612 homo_sapiens ENSP00000291568 71.4286 53.0612
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000160213 homo_sapiens ENSP00000291568 82.6531 79.5918 nomascus_leucogenys ENSNLEP00000034139 77.8846 75 ENSG00000160213 homo_sapiens ENSP00000291568 84.6939 81.6327 pan_paniscus ENSPPAP00000010856 79.8077 76.9231 ENSG00000160213 homo_sapiens ENSP00000291568 100 100 pongo_abelii ENSPPYP00000025425 100 100 ENSG00000160213 homo_sapiens ENSP00000291568 100 98.9796 pan_troglodytes ENSPTRP00000086988 100 98.9796 ENSG00000160213 homo_sapiens ENSP00000291568 83.6735 82.6531 gorilla_gorilla ENSGGOP00000003834 91.1111 90 ENSG00000160213 homo_sapiens ENSP00000291568 89.7959 77.551 sarcophilus_harrisii ENSSHAP00000035747 89.7959 77.551 ENSG00000160213 homo_sapiens ENSP00000291568 61.2245 46.9388 dasypus_novemcinctus ENSDNOP00000018166 61.2245 46.9388 ENSG00000160213 homo_sapiens ENSP00000291568 78.5714 65.3061 dasypus_novemcinctus ENSDNOP00000007574 59.6899 49.6124 ENSG00000160213 homo_sapiens ENSP00000291568 63.2653 53.0612 echinops_telfairi ENSETEP00000015953 77.5 65 ENSG00000160213 homo_sapiens ENSP00000291568 69.3878 61.2245 echinops_telfairi ENSETEP00000004820 89.4737 78.9474 ENSG00000160213 homo_sapiens ENSP00000291568 98.9796 93.8775 callithrix_jacchus ENSCJAP00000085535 98.9796 93.8775 ENSG00000160213 homo_sapiens ENSP00000291568 96.9388 89.7959 callithrix_jacchus ENSCJAP00000091885 96.9388 89.7959 ENSG00000160213 homo_sapiens ENSP00000291568 98.9796 92.8571 callithrix_jacchus ENSCJAP00000083796 98.9796 92.8571 ENSG00000160213 homo_sapiens ENSP00000291568 96.9388 91.8367 callithrix_jacchus ENSCJAP00000083039 96.9388 91.8367 ENSG00000160213 homo_sapiens ENSP00000291568 98.9796 92.8571 callithrix_jacchus ENSCJAP00000087333 98.9796 92.8571 ENSG00000160213 homo_sapiens ENSP00000291568 95.9184 90.8163 callithrix_jacchus ENSCJAP00000082418 95.9184 90.8163 ENSG00000160213 homo_sapiens ENSP00000291568 97.9592 91.8367 callithrix_jacchus ENSCJAP00000092769 97.9592 91.8367 ENSG00000160213 homo_sapiens ENSP00000291568 97.9592 94.898 cercocebus_atys ENSCATP00000038951 97.9592 94.898 ENSG00000160213 homo_sapiens ENSP00000291568 97.9592 94.898 cercocebus_atys ENSCATP00000040904 97.9592 94.898 ENSG00000160213 homo_sapiens ENSP00000291568 85.7143 82.6531 macaca_fascicularis ENSMFAP00000061902 83.1683 80.198 ENSG00000160213 homo_sapiens ENSP00000291568 85.7143 82.6531 macaca_mulatta ENSMMUP00000016139 83.1683 80.198 ENSG00000160213 homo_sapiens ENSP00000291568 95.9184 93.8775 macaca_nemestrina ENSMNEP00000011271 95.9184 93.8775 ENSG00000160213 homo_sapiens ENSP00000291568 96.9388 91.8367 papio_anubis ENSPANP00000042607 96.9388 91.8367 ENSG00000160213 homo_sapiens ENSP00000291568 97.9592 94.898 papio_anubis ENSPANP00000012813 97.9592 94.898 ENSG00000160213 homo_sapiens ENSP00000291568 95.9184 92.8571 mandrillus_leucophaeus ENSMLEP00000005974 95.9184 92.8571 ENSG00000160213 homo_sapiens ENSP00000291568 85.7143 79.5918 mandrillus_leucophaeus ENSMLEP00000014113 80.7692 75 ENSG00000160213 homo_sapiens ENSP00000291568 89.7959 76.5306 tursiops_truncatus ENSTTRP00000010578 90.7216 77.3196 ENSG00000160213 homo_sapiens ENSP00000291568 79.5918 68.3673 vulpes_vulpes ENSVVUP00000033899 73.5849 63.2075 ENSG00000160213 homo_sapiens ENSP00000291568 87.7551 78.5714 mus_spretus MGP_SPRETEiJ_P0024810 87.7551 78.5714 ENSG00000160213 homo_sapiens ENSP00000291568 94.898 85.7143 equus_asinus ENSEASP00005040941 66.4286 60 ENSG00000160213 homo_sapiens ENSP00000291568 92.8571 82.6531 equus_asinus ENSEASP00005041376 47.8947 42.6316 ENSG00000160213 homo_sapiens ENSP00000291568 69.3878 55.102 capra_hircus ENSCHIP00000033540 70.8333 56.25 ENSG00000160213 homo_sapiens ENSP00000291568 92.8571 79.5918 capra_hircus ENSCHIP00000019105 90.099 77.2277 ENSG00000160213 homo_sapiens ENSP00000291568 82.6531 71.4286 capra_hircus ENSCHIP00000027681 80.198 69.3069 ENSG00000160213 homo_sapiens ENSP00000291568 95.9184 86.7347 loxodonta_africana ENSLAFP00000002226 90.3846 81.7308 ENSG00000160213 homo_sapiens ENSP00000291568 88.7755 77.551 panthera_leo ENSPLOP00000023387 88.7755 77.551 ENSG00000160213 homo_sapiens ENSP00000291568 70.4082 60.2041 ailuropoda_melanoleuca ENSAMEP00000012033 88.4615 75.641 ENSG00000160213 homo_sapiens ENSP00000291568 85.7143 74.4898 bos_indicus_hybrid ENSBIXP00005016913 34.0081 29.5547 ENSG00000160213 homo_sapiens ENSP00000291568 73.4694 64.2857 oryctolagus_cuniculus ENSOCUP00000018156 93.5065 81.8182 ENSG00000160213 homo_sapiens ENSP00000291568 95.9184 85.7143 equus_caballus ENSECAP00000069329 43.7209 39.0698 ENSG00000160213 homo_sapiens ENSP00000291568 95.9184 86.7347 equus_caballus ENSECAP00000087834 43.7209 39.5349 ENSG00000160213 homo_sapiens ENSP00000291568 92.8571 81.6327 canis_lupus_familiaris ENSCAFP00845025721 92.8571 81.6327 ENSG00000160213 homo_sapiens ENSP00000291568 89.7959 78.5714 panthera_pardus ENSPPRP00000019189 89.7959 78.5714 ENSG00000160213 homo_sapiens ENSP00000291568 82.6531 69.3878 marmota_marmota_marmota ENSMMMP00000012586 55.4795 46.5753 ENSG00000160213 homo_sapiens ENSP00000291568 85.7143 73.4694 balaenoptera_musculus ENSBMSP00010009277 31.6981 27.1698 ENSG00000160213 homo_sapiens ENSP00000291568 89.7959 73.4694 cavia_porcellus ENSCPOP00000029747 89.7959 73.4694 ENSG00000160213 homo_sapiens ENSP00000291568 67.3469 59.1837 felis_catus ENSFCAP00000037752 64.0777 56.3107 ENSG00000160213 homo_sapiens ENSP00000291568 89.7959 79.5918 felis_catus ENSFCAP00000055169 58.6667 52 ENSG00000160213 homo_sapiens ENSP00000291568 89.7959 79.5918 ursus_americanus ENSUAMP00000035251 89.7959 79.5918 ENSG00000160213 homo_sapiens ENSP00000291568 85.7143 75.5102 monodelphis_domestica ENSMODP00000026304 64.6154 56.9231 ENSG00000160213 homo_sapiens ENSP00000291568 89.7959 79.5918 bison_bison_bison ENSBBBP00000006163 89.7959 79.5918 ENSG00000160213 homo_sapiens ENSP00000291568 89.7959 76.5306 monodon_monoceros ENSMMNP00015003111 90.7216 77.3196 ENSG00000160213 homo_sapiens ENSP00000291568 91.8367 84.6939 sus_scrofa ENSSSCP00000021841 91.8367 84.6939 ENSG00000160213 homo_sapiens ENSP00000291568 93.8775 87.7551 microcebus_murinus ENSMICP00000032375 93.8775 87.7551 ENSG00000160213 homo_sapiens ENSP00000291568 52.0408 39.7959 jaculus_jaculus ENSJJAP00000018602 77.2727 59.0909 ENSG00000160213 homo_sapiens ENSP00000291568 65.3061 54.0816 ovis_aries_rambouillet ENSOARP00020000868 71.9101 59.5506 ENSG00000160213 homo_sapiens ENSP00000291568 92.8571 80.6122 ovis_aries_rambouillet ENSOARP00020007576 92.8571 80.6122 ENSG00000160213 homo_sapiens ENSP00000291568 91.8367 84.6939 ochotona_princeps ENSOPRP00000009430 91.8367 84.6939 ENSG00000160213 homo_sapiens ENSP00000291568 89.7959 76.5306 delphinapterus_leucas ENSDLEP00000029384 90.7216 77.3196 ENSG00000160213 homo_sapiens ENSP00000291568 75.5102 62.2449 physeter_catodon ENSPCTP00005021205 78.7234 64.8936 ENSG00000160213 homo_sapiens ENSP00000291568 89.7959 79.5918 mus_caroli MGP_CAROLIEiJ_P0023664 89.7959 79.5918 ENSG00000160213 homo_sapiens ENSP00000291568 87.7551 78.5714 mus_musculus ENSMUSP00000005185 87.7551 78.5714 ENSG00000160213 homo_sapiens ENSP00000291568 68.3673 57.1429 dipodomys_ordii ENSDORP00000018009 88.1579 73.6842 ENSG00000160213 homo_sapiens ENSP00000291568 70.4082 63.2653 mustela_putorius_furo ENSMPUP00000009745 89.6104 80.5195 ENSG00000160213 homo_sapiens ENSP00000291568 87.7551 82.6531 aotus_nancymaae ENSANAP00000009198 92.4731 87.0968 ENSG00000160213 homo_sapiens ENSP00000291568 98.9796 92.8571 aotus_nancymaae ENSANAP00000041586 98.9796 92.8571 ENSG00000160213 homo_sapiens ENSP00000291568 83.6735 77.551 saimiri_boliviensis_boliviensis ENSSBOP00000023029 95.3488 88.3721 ENSG00000160213 homo_sapiens ENSP00000291568 86.7347 80.6122 saimiri_boliviensis_boliviensis ENSSBOP00000009403 90.4255 84.0426 ENSG00000160213 homo_sapiens ENSP00000291568 92.8571 88.7755 chlorocebus_sabaeus ENSCSAP00000017590 92.8571 88.7755 ENSG00000160213 homo_sapiens ENSP00000291568 96.9388 94.898 chlorocebus_sabaeus ENSCSAP00000004208 96.9388 94.898 ENSG00000160213 homo_sapiens ENSP00000291568 50 42.8571 tupaia_belangeri ENSTBEP00000014615 79.0323 67.7419 ENSG00000160213 homo_sapiens ENSP00000291568 87.7551 75.5102 tupaia_belangeri ENSTBEP00000000865 87.7551 75.5102 ENSG00000160213 homo_sapiens ENSP00000291568 89.7959 78.5714 mesocricetus_auratus ENSMAUP00000009921 89.7959 78.5714 ENSG00000160213 homo_sapiens ENSP00000291568 82.6531 70.4082 phocoena_sinus ENSPSNP00000014174 33.61 28.6307 ENSG00000160213 homo_sapiens ENSP00000291568 90.8163 79.5918 camelus_dromedarius ENSCDRP00005019017 90.8163 79.5918 ENSG00000160213 homo_sapiens ENSP00000291568 90.8163 78.5714 camelus_dromedarius ENSCDRP00005016061 90.8163 78.5714 ENSG00000160213 homo_sapiens ENSP00000291568 93.8775 79.5918 carlito_syrichta ENSTSYP00000025438 93.8775 79.5918 ENSG00000160213 homo_sapiens ENSP00000291568 70.4082 59.1837 panthera_tigris_altaica ENSPTIP00000022089 90.7895 76.3158 ENSG00000160213 homo_sapiens ENSP00000291568 88.7755 78.5714 rattus_norvegicus ENSRNOP00000001593 88.7755 78.5714 ENSG00000160213 homo_sapiens ENSP00000291568 93.8775 89.7959 prolemur_simus ENSPSMP00000001441 93.8775 89.7959 ENSG00000160213 homo_sapiens ENSP00000291568 92.8571 79.5918 microtus_ochrogaster ENSMOCP00000026130 92.8571 79.5918 ENSG00000160213 homo_sapiens ENSP00000291568 92.8571 80.6122 peromyscus_maniculatus_bairdii ENSPEMP00000034391 92.8571 80.6122 ENSG00000160213 homo_sapiens ENSP00000291568 51.0204 43.8776 bos_mutus ENSBMUP00000013788 64.9351 55.8442 ENSG00000160213 homo_sapiens ENSP00000291568 90.8163 78.5714 bos_mutus ENSBMUP00000017298 59.7315 51.6779 ENSG00000160213 homo_sapiens ENSP00000291568 87.7551 78.5714 mus_spicilegus ENSMSIP00000031689 87.7551 78.5714 ENSG00000160213 homo_sapiens ENSP00000291568 89.7959 79.5918 cricetulus_griseus_chok1gshd ENSCGRP00001026353 89.7959 79.5918 ENSG00000160213 homo_sapiens ENSP00000291568 81.6327 68.3673 pteropus_vampyrus ENSPVAP00000006627 80.8081 67.6768 ENSG00000160213 homo_sapiens ENSP00000291568 79.5918 72.449 myotis_lucifugus ENSMLUP00000004499 79.5918 72.449 ENSG00000160213 homo_sapiens ENSP00000291568 82.6531 72.449 myotis_lucifugus ENSMLUP00000018682 78.6408 68.932 ENSG00000160213 homo_sapiens ENSP00000291568 84.6939 75.5102 myotis_lucifugus ENSMLUP00000021664 79.8077 71.1538 ENSG00000160213 homo_sapiens ENSP00000291568 80.6122 73.4694 myotis_lucifugus ENSMLUP00000004504 74.5283 67.9245 ENSG00000160213 homo_sapiens ENSP00000291568 57.1429 50 vombatus_ursinus ENSVURP00010012985 87.5 76.5625 ENSG00000160213 homo_sapiens ENSP00000291568 75.5102 62.2449 vombatus_ursinus ENSVURP00010017702 78.7234 64.8936 ENSG00000160213 homo_sapiens ENSP00000291568 56.1224 46.9388 vombatus_ursinus ENSVURP00010006756 79.7101 66.6667 ENSG00000160213 homo_sapiens ENSP00000291568 89.7959 76.5306 vombatus_ursinus ENSVURP00010030406 89.7959 76.5306 ENSG00000160213 homo_sapiens ENSP00000291568 84.6939 71.4286 rhinolophus_ferrumequinum ENSRFEP00010000464 84.6939 71.4286 ENSG00000160213 homo_sapiens ENSP00000291568 73.4694 66.3265 neovison_vison ENSNVIP00000008883 75 67.7083 ENSG00000160213 homo_sapiens ENSP00000291568 91.8367 78.5714 bos_taurus ENSBTAP00000000683 60.4027 51.6779 ENSG00000160213 homo_sapiens ENSP00000291568 85.7143 74.4898 bos_taurus ENSBTAP00000024208 83.1683 72.2772 ENSG00000160213 homo_sapiens ENSP00000291568 86.7347 71.4286 heterocephalus_glaber_female ENSHGLP00000054197 86.7347 71.4286 ENSG00000160213 homo_sapiens ENSP00000291568 97.9592 94.898 rhinopithecus_bieti ENSRBIP00000016741 97.9592 94.898 ENSG00000160213 homo_sapiens ENSP00000291568 95.9184 92.8571 rhinopithecus_bieti ENSRBIP00000001681 95.9184 92.8571 ENSG00000160213 homo_sapiens ENSP00000291568 92.8571 81.6327 canis_lupus_dingo ENSCAFP00020024121 92.8571 81.6327 ENSG00000160213 homo_sapiens ENSP00000291568 95.9184 90.8163 sciurus_vulgaris ENSSVLP00005031430 95.9184 90.8163 ENSG00000160213 homo_sapiens ENSP00000291568 67.3469 50 phascolarctos_cinereus ENSPCIP00000032740 63.4615 47.1154 ENSG00000160213 homo_sapiens ENSP00000291568 90.8163 79.5918 phascolarctos_cinereus ENSPCIP00000020385 90.8163 79.5918 ENSG00000160213 homo_sapiens ENSP00000291568 86.7347 74.4898 phascolarctos_cinereus ENSPCIP00000013229 86.7347 74.4898 ENSG00000160213 homo_sapiens ENSP00000291568 92.8571 81.6327 procavia_capensis ENSPCAP00000007762 92.8571 81.6327 ENSG00000160213 homo_sapiens ENSP00000291568 73.4694 64.2857 procavia_capensis ENSPCAP00000000572 94.7368 82.8947 ENSG00000160213 homo_sapiens ENSP00000291568 90.8163 84.6939 nannospalax_galili ENSNGAP00000002343 90.8163 84.6939 ENSG00000160213 homo_sapiens ENSP00000291568 85.7143 74.4898 bos_grunniens ENSBGRP00000034513 34.0081 29.5547 ENSG00000160213 homo_sapiens ENSP00000291568 73.4694 58.1633 bos_grunniens ENSBGRP00000025585 43.9024 34.7561 ENSG00000160213 homo_sapiens ENSP00000291568 90.8163 78.5714 chinchilla_lanigera ENSCLAP00000014452 90.8163 78.5714 ENSG00000160213 homo_sapiens ENSP00000291568 91.8367 78.5714 cervus_hanglu_yarkandensis ENSCHYP00000015738 26.5487 22.7139 ENSG00000160213 homo_sapiens ENSP00000291568 55.102 48.9796 cervus_hanglu_yarkandensis ENSCHYP00000013648 61.3636 54.5455 ENSG00000160213 homo_sapiens ENSP00000291568 72.449 57.1429 cervus_hanglu_yarkandensis ENSCHYP00000027883 75.5319 59.5745 ENSG00000160213 homo_sapiens ENSP00000291568 68.3673 48.9796 cervus_hanglu_yarkandensis ENSCHYP00000005746 51.938 37.2093 ENSG00000160213 homo_sapiens ENSP00000291568 84.6939 71.4286 cervus_hanglu_yarkandensis ENSCHYP00000005472 86.4583 72.9167 ENSG00000160213 homo_sapiens ENSP00000291568 90.8163 83.6735 catagonus_wagneri ENSCWAP00000028529 90.8163 83.6735 ENSG00000160213 homo_sapiens ENSP00000291568 70.4082 64.2857 ictidomys_tridecemlineatus ENSSTOP00000017118 90.7895 82.8947 ENSG00000160213 homo_sapiens ENSP00000291568 94.898 87.7551 otolemur_garnettii ENSOGAP00000005450 94.898 87.7551 ENSG00000160213 homo_sapiens ENSP00000291568 72.449 65.3061 cebus_imitator ENSCCAP00000013708 86.5854 78.0488 ENSG00000160213 homo_sapiens ENSP00000291568 97.9592 93.8775 cebus_imitator ENSCCAP00000024600 97.9592 93.8775 ENSG00000160213 homo_sapiens ENSP00000291568 77.551 60.2041 urocitellus_parryii ENSUPAP00010016374 56.2963 43.7037 ENSG00000160213 homo_sapiens ENSP00000291568 92.8571 85.7143 urocitellus_parryii ENSUPAP00010003937 92.8571 85.7143 ENSG00000160213 homo_sapiens ENSP00000291568 83.6735 71.4286 moschus_moschiferus ENSMMSP00000014987 81.1881 69.3069 ENSG00000160213 homo_sapiens ENSP00000291568 83.6735 76.5306 rhinopithecus_roxellana ENSRROP00000029537 88.172 80.6452 ENSG00000160213 homo_sapiens ENSP00000291568 89.7959 81.6327 mus_pahari MGP_PahariEiJ_P0086819 89.7959 81.6327 ENSG00000160213 homo_sapiens ENSP00000291568 96.9388 89.7959 propithecus_coquereli ENSPCOP00000020510 96.9388 89.7959 ENSG00000160213 homo_sapiens ENSP00000291568 63.2653 41.8367 callorhinchus_milii ENSCMIP00000006841 64.5833 42.7083 ENSG00000160213 homo_sapiens ENSP00000291568 75.5102 59.1837 lepisosteus_oculatus ENSLOCP00000003795 74 58 ENSG00000160213 homo_sapiens ENSP00000291568 77.551 60.2041 lepisosteus_oculatus ENSLOCP00000003807 74.5098 57.8431 ENSG00000160213 homo_sapiens ENSP00000291568 72.449 54.0816 danio_rerio ENSDARP00000043192 71 53 ENSG00000160213 homo_sapiens ENSP00000291568 73.4694 55.102 danio_rerio ENSDARP00000032643 72 54 ENSG00000160213 homo_sapiens ENSP00000291568 71.4286 47.9592 carassius_auratus ENSCARP00000023176 70 47 ENSG00000160213 homo_sapiens ENSP00000291568 64.2857 52.0408 carassius_auratus ENSCARP00000101931 42.2819 34.2282 ENSG00000160213 homo_sapiens ENSP00000291568 68.3673 52.0408 carassius_auratus ENSCARP00000075080 67 51 ENSG00000160213 homo_sapiens ENSP00000291568 68.3673 54.0816 carassius_auratus ENSCARP00000006728 67 53 ENSG00000160213 homo_sapiens ENSP00000291568 70.4082 50 astyanax_mexicanus ENSAMXP00000034591 69 49 ENSG00000160213 homo_sapiens ENSP00000291568 67.3469 56.1224 ictalurus_punctatus ENSIPUP00000016472 50 41.6667 ENSG00000160213 homo_sapiens ENSP00000291568 67.3469 50 ictalurus_punctatus ENSIPUP00000031339 61.6822 45.7944 ENSG00000160213 homo_sapiens ENSP00000291568 68.3673 55.102 ictalurus_punctatus ENSIPUP00000016491 63.8095 51.4286 ENSG00000160213 homo_sapiens ENSP00000291568 69.3878 52.0408 ictalurus_punctatus ENSIPUP00000016439 65.3846 49.0385 ENSG00000160213 homo_sapiens ENSP00000291568 66.3265 51.0204 esox_lucius ENSELUP00000027214 65 50 ENSG00000160213 homo_sapiens ENSP00000291568 66.3265 50 electrophorus_electricus ENSEEEP00000041797 65 49 ENSG00000160213 homo_sapiens ENSP00000291568 61.2245 51.0204 electrophorus_electricus ENSEEEP00000043046 60 50 ENSG00000160213 homo_sapiens ENSP00000291568 65.3061 48.9796 oncorhynchus_kisutch ENSOKIP00005103604 64.6465 48.4848 ENSG00000160213 homo_sapiens ENSP00000291568 65.3061 46.9388 oncorhynchus_kisutch ENSOKIP00005025824 64.6465 46.4646 ENSG00000160213 homo_sapiens ENSP00000291568 65.3061 46.9388 oncorhynchus_mykiss ENSOMYP00000068525 64.6465 46.4646 ENSG00000160213 homo_sapiens ENSP00000291568 64.2857 45.9184 oncorhynchus_mykiss ENSOMYP00000068538 63.6364 45.4545 ENSG00000160213 homo_sapiens ENSP00000291568 61.2245 48.9796 oncorhynchus_mykiss ENSOMYP00000129286 63.8298 51.0638 ENSG00000160213 homo_sapiens ENSP00000291568 66.3265 46.9388 salmo_salar ENSSSAP00000005398 58.5586 41.4414 ENSG00000160213 homo_sapiens ENSP00000291568 66.3265 46.9388 salmo_trutta ENSSTUP00000031438 65.6566 46.4646 ENSG00000160213 homo_sapiens ENSP00000291568 68.3673 51.0204 gadus_morhua ENSGMOP00000033021 65.0485 48.5437 ENSG00000160213 homo_sapiens ENSP00000291568 66.3265 46.9388 fundulus_heteroclitus ENSFHEP00000015843 65.6566 46.4646 ENSG00000160213 homo_sapiens ENSP00000291568 67.3469 47.9592 poecilia_reticulata ENSPREP00000027523 67.3469 47.9592 ENSG00000160213 homo_sapiens ENSP00000291568 66.3265 47.9592 poecilia_reticulata ENSPREP00000027642 64.3564 46.5347 ENSG00000160213 homo_sapiens ENSP00000291568 66.3265 46.9388 xiphophorus_maculatus ENSXMAP00000010130 64.3564 45.5446 ENSG00000160213 homo_sapiens ENSP00000291568 69.3878 46.9388 xiphophorus_maculatus ENSXMAP00000010134 68 46 ENSG00000160213 homo_sapiens ENSP00000291568 64.2857 45.9184 oryzias_latipes ENSORLP00000038685 63.6364 45.4545 ENSG00000160213 homo_sapiens ENSP00000291568 63.2653 48.9796 cyclopterus_lumpus ENSCLMP00005045989 60.7843 47.0588 ENSG00000160213 homo_sapiens ENSP00000291568 58.1633 42.8571 oreochromis_niloticus ENSONIP00000068861 57 42 ENSG00000160213 homo_sapiens ENSP00000291568 58.1633 42.8571 oreochromis_niloticus ENSONIP00000076883 57 42 ENSG00000160213 homo_sapiens ENSP00000291568 55.102 39.7959 oreochromis_niloticus ENSONIP00000022642 60.6742 43.8202 ENSG00000160213 homo_sapiens ENSP00000291568 58.1633 42.8571 oreochromis_niloticus ENSONIP00000037766 57 42 ENSG00000160213 homo_sapiens ENSP00000291568 58.1633 42.8571 oreochromis_niloticus ENSONIP00000054078 57 42 ENSG00000160213 homo_sapiens ENSP00000291568 64.2857 44.898 oreochromis_niloticus ENSONIP00000061491 51.2195 35.7724 ENSG00000160213 homo_sapiens ENSP00000291568 58.1633 42.8571 oreochromis_niloticus ENSONIP00000057492 57 42 ENSG00000160213 homo_sapiens ENSP00000291568 64.2857 43.8776 oreochromis_niloticus ENSONIP00000047138 64.9485 44.3299 ENSG00000160213 homo_sapiens ENSP00000291568 63.2653 44.898 oreochromis_niloticus ENSONIP00000031842 61.3861 43.5644 ENSG00000160213 homo_sapiens ENSP00000291568 64.2857 44.898 oreochromis_niloticus ENSONIP00000060711 51.2195 35.7724 ENSG00000160213 homo_sapiens ENSP00000291568 67.3469 46.9388 astatotilapia_calliptera ENSACLP00000039993 66.6667 46.4646 ENSG00000160213 homo_sapiens ENSP00000291568 55.102 37.7551 astatotilapia_calliptera ENSACLP00000039952 42.1875 28.9062 ENSG00000160213 homo_sapiens ENSP00000291568 55.102 37.7551 astatotilapia_calliptera ENSACLP00000039887 42.1875 28.9062 ENSG00000160213 homo_sapiens ENSP00000291568 58.1633 42.8571 astatotilapia_calliptera ENSACLP00000039969 57 42 ENSG00000160213 homo_sapiens ENSP00000291568 62.2449 48.9796 sparus_aurata ENSSAUP00010034381 61 48 ENSG00000160213 homo_sapiens ENSP00000291568 66.3265 45.9184 lates_calcarifer ENSLCAP00010033370 45.4545 31.4685 ENSG00000160213 homo_sapiens ENSP00000291568 66.3265 45.9184 lates_calcarifer ENSLCAP00010056760 45.4545 31.4685 ENSG00000160213 homo_sapiens ENSP00000291568 62.2449 44.898 xenopus_tropicalis ENSXETP00000101997 60.396 43.5644 ENSG00000160213 homo_sapiens ENSP00000291568 85.7143 72.449 chrysemys_picta_bellii ENSCPBP00000000923 85.7143 72.449 ENSG00000160213 homo_sapiens ENSP00000291568 76.5306 59.1837 sphenodon_punctatus ENSSPUP00000006366 76.5306 59.1837 ENSG00000160213 homo_sapiens ENSP00000291568 66.3265 51.0204 crocodylus_porosus ENSCPRP00005017698 67.0103 51.5464 ENSG00000160213 homo_sapiens ENSP00000291568 57.1429 44.898 laticauda_laticaudata ENSLLTP00000010933 41.1765 32.3529 ENSG00000160213 homo_sapiens ENSP00000291568 72.449 52.0408 notechis_scutatus ENSNSUP00000026673 60.6838 43.5897 ENSG00000160213 homo_sapiens ENSP00000291568 82.6531 62.2449 pseudonaja_textilis ENSPTXP00000021001 82.6531 62.2449 ENSG00000160213 homo_sapiens ENSP00000291568 87.7551 73.4694 anas_platyrhynchos_platyrhynchos ENSAPLP00000032139 87.7551 73.4694 ENSG00000160213 homo_sapiens ENSP00000291568 78.5714 62.2449 gallus_gallus ENSGALP00010031782 57.8947 45.8647 ENSG00000160213 homo_sapiens ENSP00000291568 84.6939 69.3878 meleagris_gallopavo ENSMGAP00000014803 84.6939 69.3878 ENSG00000160213 homo_sapiens ENSP00000291568 75.5102 59.1837 serinus_canaria ENSSCAP00000015688 61.6667 48.3333 ENSG00000160213 homo_sapiens ENSP00000291568 86.7347 70.4082 parus_major ENSPMJP00000013258 38.8128 31.5068 ENSG00000160213 homo_sapiens ENSP00000291568 79.5918 63.2653 anolis_carolinensis ENSACAP00000000389 74.2857 59.0476 ENSG00000160213 homo_sapiens ENSP00000291568 57.1429 40.8163 neolamprologus_brichardi ENSNBRP00000029920 55.4455 39.604 ENSG00000160213 homo_sapiens ENSP00000291568 62.2449 46.9388 neolamprologus_brichardi ENSNBRP00000029978 61.6162 46.4646 ENSG00000160213 homo_sapiens ENSP00000291568 82.6531 60.2041 naja_naja ENSNNAP00000014894 82.6531 60.2041 ENSG00000160213 homo_sapiens ENSP00000291568 65.3061 48.9796 podarcis_muralis ENSPMRP00000027474 65.3061 48.9796 ENSG00000160213 homo_sapiens ENSP00000291568 71.4286 55.102 geospiza_fortis ENSGFOP00000002028 76.087 58.6957 ENSG00000160213 homo_sapiens ENSP00000291568 84.6939 70.4082 taeniopygia_guttata ENSTGUP00000013739 84.6939 70.4082 ENSG00000160213 homo_sapiens ENSP00000291568 54.0816 34.6939 kryptolebias_marmoratus ENSKMAP00000013174 56.9892 36.5591 ENSG00000160213 homo_sapiens ENSP00000291568 62.2449 41.8367 kryptolebias_marmoratus ENSKMAP00000013129 61.6162 41.4141 ENSG00000160213 homo_sapiens ENSP00000291568 81.6327 63.2653 salvator_merianae ENSSMRP00000014220 81.6327 63.2653 ENSG00000160213 homo_sapiens ENSP00000291568 62.2449 46.9388 amphiprion_percula ENSAPEP00000027048 62.2449 46.9388 ENSG00000160213 homo_sapiens ENSP00000291568 66.3265 50 oryzias_sinensis ENSOSIP00000003607 64.3564 48.5149 ENSG00000160213 homo_sapiens ENSP00000291568 63.2653 46.9388 oryzias_sinensis ENSOSIP00000004889 47.3282 35.1145 ENSG00000160213 homo_sapiens ENSP00000291568 63.2653 46.9388 oryzias_sinensis ENSOSIP00000032608 47.3282 35.1145 ENSG00000160213 homo_sapiens ENSP00000291568 77.551 61.2245 pelodiscus_sinensis ENSPSIP00000004114 77.551 61.2245 ENSG00000160213 homo_sapiens ENSP00000291568 82.6531 68.3673 pelodiscus_sinensis ENSPSIP00000018871 82.6531 68.3673 ENSG00000160213 homo_sapiens ENSP00000291568 85.7143 71.4286 gopherus_evgoodei ENSGEVP00005004012 84.8485 70.7071 ENSG00000160213 homo_sapiens ENSP00000291568 84.6939 70.4082 chelonoidis_abingdonii ENSCABP00000002153 83.8384 69.697 ENSG00000160213 homo_sapiens ENSP00000291568 63.2653 47.9592 seriola_dumerili ENSSDUP00000021302 45.2555 34.3066 ENSG00000160213 homo_sapiens ENSP00000291568 62.2449 48.9796 cottoperca_gobio ENSCGOP00000032388 49.5935 39.0244 ENSG00000160213 homo_sapiens ENSP00000291568 76.5306 61.2245 struthio_camelus_australis ENSSCUP00000024354 63.0252 50.4202 ENSG00000160213 homo_sapiens ENSP00000291568 66.3265 48.9796 anser_brachyrhynchus ENSABRP00000002624 44.8276 33.1034 ENSG00000160213 homo_sapiens ENSP00000291568 60.2041 40.8163 cynoglossus_semilaevis ENSCSEP00000026647 60.8247 41.2371 ENSG00000160213 homo_sapiens ENSP00000291568 62.2449 46.9388 cynoglossus_semilaevis ENSCSEP00000026490 61.6162 46.4646 ENSG00000160213 homo_sapiens ENSP00000291568 67.3469 48.9796 poecilia_formosa ENSPFOP00000010041 65.3465 47.5248 ENSG00000160213 homo_sapiens ENSP00000291568 68.3673 48.9796 poecilia_formosa ENSPFOP00000010047 67 48 ENSG00000160213 homo_sapiens ENSP00000291568 68.3673 55.102 myripristis_murdjan ENSMMDP00005007461 67 54 ENSG00000160213 homo_sapiens ENSP00000291568 61.2245 47.9592 sander_lucioperca ENSSLUP00000034726 46.5116 36.4341 ENSG00000160213 homo_sapiens ENSP00000291568 86.7347 71.4286 strigops_habroptila ENSSHBP00005008884 86.7347 71.4286 ENSG00000160213 homo_sapiens ENSP00000291568 62.2449 46.9388 amphiprion_ocellaris ENSAOCP00000006052 62.2449 46.9388 ENSG00000160213 homo_sapiens ENSP00000291568 85.7143 70.4082 terrapene_carolina_triunguis ENSTMTP00000023164 85.7143 70.4082 ENSG00000160213 homo_sapiens ENSP00000291568 65.3061 48.9796 hucho_hucho ENSHHUP00000023241 64.6465 48.4848 ENSG00000160213 homo_sapiens ENSP00000291568 65.3061 45.9184 hucho_hucho ENSHHUP00000085468 49.6124 34.8837 ENSG00000160213 homo_sapiens ENSP00000291568 58.1633 41.8367 betta_splendens ENSBSLP00000002891 58.7629 42.268 ENSG00000160213 homo_sapiens ENSP00000291568 69.3878 54.0816 pygocentrus_nattereri ENSPNAP00000014447 65.3846 50.9615 ENSG00000160213 homo_sapiens ENSP00000291568 64.2857 47.9592 seriola_lalandi_dorsalis ENSSLDP00000017129 63 47 ENSG00000160213 homo_sapiens ENSP00000291568 64.2857 47.9592 mastacembelus_armatus ENSMAMP00000002399 63 47 ENSG00000160213 homo_sapiens ENSP00000291568 65.3061 46.9388 oncorhynchus_tshawytscha ENSOTSP00005030534 64.6465 46.4646 ENSG00000160213 homo_sapiens ENSP00000291568 59.1837 43.8776 acanthochromis_polyacanthus ENSAPOP00000029505 58 43 ENSG00000160213 homo_sapiens ENSP00000291568 86.7347 70.4082 aquila_chrysaetos_chrysaetos ENSACCP00020023279 86.7347 70.4082 ENSG00000160213 homo_sapiens ENSP00000291568 55.102 43.8776 nothobranchius_furzeri ENSNFUP00015046070 51.9231 41.3462 ENSG00000160213 homo_sapiens ENSP00000291568 64.2857 43.8776 cyprinodon_variegatus ENSCVAP00000004759 51.6393 35.2459 ENSG00000160213 homo_sapiens ENSP00000291568 62.2449 47.9592 denticeps_clupeoides ENSDCDP00000035458 59.2233 45.6311 ENSG00000160213 homo_sapiens ENSP00000291568 69.3878 52.0408 denticeps_clupeoides ENSDCDP00000035457 68.6869 51.5152 ENSG00000160213 homo_sapiens ENSP00000291568 58.1633 39.7959 larimichthys_crocea ENSLCRP00005060121 54.8077 37.5 ENSG00000160213 homo_sapiens ENSP00000291568 60.2041 46.9388 larimichthys_crocea ENSLCRP00005060134 50.4273 39.3162 ENSG00000160213 homo_sapiens ENSP00000291568 77.551 60.2041 ficedula_albicollis ENSFALP00000005165 78.3505 60.8247 ENSG00000160213 homo_sapiens ENSP00000291568 60.2041 46.9388 hippocampus_comes ENSHCOP00000023041 56.1905 43.8095 ENSG00000160213 homo_sapiens ENSP00000291568 61.2245 43.8776 hippocampus_comes ENSHCOP00000023047 58.8235 42.1569 ENSG00000160213 homo_sapiens ENSP00000291568 62.2449 44.898 hippocampus_comes ENSHCOP00000008911 59.8039 43.1373 ENSG00000160213 homo_sapiens ENSP00000291568 66.3265 51.0204 hippocampus_comes ENSHCOP00000003779 43.0464 33.1126 ENSG00000160213 homo_sapiens ENSP00000291568 62.2449 45.9184 cyprinus_carpio_carpio ENSCCRP00000044634 54.955 40.5405 ENSG00000160213 homo_sapiens ENSP00000291568 66.3265 53.0612 cyprinus_carpio_carpio ENSCCRP00000103811 40.3727 32.2981 ENSG00000160213 homo_sapiens ENSP00000291568 66.3265 54.0816 cyprinus_carpio_carpio ENSCCRP00000145687 33.6788 27.4611 ENSG00000160213 homo_sapiens ENSP00000291568 85.7143 71.4286 coturnix_japonica ENSCJPP00005020816 85.7143 71.4286 ENSG00000160213 homo_sapiens ENSP00000291568 68.3673 48.9796 poecilia_latipinna ENSPLAP00000018973 68.3673 48.9796 ENSG00000160213 homo_sapiens ENSP00000291568 67.3469 48.9796 poecilia_latipinna ENSPLAP00000001397 65.3465 47.5248 ENSG00000160213 homo_sapiens ENSP00000291568 66.3265 48.9796 sinocyclocheilus_grahami ENSSGRP00000051950 69.8925 51.6129 ENSG00000160213 homo_sapiens ENSP00000291568 68.3673 55.102 sinocyclocheilus_grahami ENSSGRP00000081827 67 54 ENSG00000160213 homo_sapiens ENSP00000291568 68.3673 53.0612 sinocyclocheilus_grahami ENSSGRP00000089027 67 52 ENSG00000160213 homo_sapiens ENSP00000291568 72.449 51.0204 sinocyclocheilus_grahami ENSSGRP00000088822 71 50 ENSG00000160213 homo_sapiens ENSP00000291568 65.3061 48.9796 sinocyclocheilus_grahami ENSSGRP00000051976 59.2593 44.4444 ENSG00000160213 homo_sapiens ENSP00000291568 55.102 37.7551 maylandia_zebra ENSMZEP00005029454 40.2985 27.6119 ENSG00000160213 homo_sapiens ENSP00000291568 58.1633 42.8571 maylandia_zebra ENSMZEP00005029462 57 42 ENSG00000160213 homo_sapiens ENSP00000291568 67.3469 46.9388 maylandia_zebra ENSMZEP00005029464 66.6667 46.4646 ENSG00000160213 homo_sapiens ENSP00000291568 67.3469 50 paramormyrops_kingsleyae ENSPKIP00000011772 65.3465 48.5149 ENSG00000160213 homo_sapiens ENSP00000291568 65.3061 52.0408 scleropages_formosus ENSSFOP00015021229 64 51 ENSG00000160213 homo_sapiens ENSP00000291568 58.1633 42.8571 leptobrachium_leishanense ENSLLEP00000042219 60.6383 44.6809 ENSG00000160213 homo_sapiens ENSP00000291568 63.2653 41.8367 leptobrachium_leishanense ENSLLEP00000002095 63.2653 41.8367 ENSG00000160213 homo_sapiens ENSP00000291568 62.2449 40.8163 oryzias_melastigma ENSOMEP00000005592 61.6162 40.404
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0002020 enables protease binding 2 IDA,IPI Homo_sapiens(9606) Function GO:0003723 enables RNA binding 1 HDA Homo_sapiens(9606) Function GO:0004866 enables endopeptidase inhibitor activity 1 IDA Homo_sapiens(9606) Function GO:0004869 enables cysteine-type endopeptidase inhibitor activity 2 IBA,IDA Homo_sapiens(9606) Function GO:0005576 located_in extracellular region 1 TAS Homo_sapiens(9606) Component GO:0005615 located_in extracellular space 2 HDA,IDA Homo_sapiens(9606) Component GO:0005634 located_in nucleus 1 IDA Homo_sapiens(9606) Component GO:0005730 located_in nucleolus 1 IDA Homo_sapiens(9606) Component GO:0005737 located_in cytoplasm 1 IDA Homo_sapiens(9606) Component GO:0005829 is_active_in cytosol 2 IBA,IDA Homo_sapiens(9606) Component GO:0008344 involved_in adult locomotory behavior 1 IEA Homo_sapiens(9606) Process GO:0010466 involved_in negative regulation of peptidase activity 1 IDA Homo_sapiens(9606) Process GO:0034774 located_in secretory granule lumen 1 TAS Homo_sapiens(9606) Component GO:0045861 involved_in negative regulation of proteolysis 1 IDA Homo_sapiens(9606) Process GO:0062023 located_in collagen-containing extracellular matrix 1 HDA Homo_sapiens(9606) Component GO:0070062 located_in extracellular exosome 1 HDA Homo_sapiens(9606) Component GO:1904724 located_in tertiary granule lumen 1 TAS Homo_sapiens(9606) Component GO:1904813 located_in ficolin-1-rich granule lumen 1 TAS Homo_sapiens(9606) Component
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