Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Disease
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations Nucleoli
BulkPerturb-seq

Description

Ensembl ID ENSG00000159374 Gene ID 130951 Accession 25183
Symbol M1AP Alias D6Mm5e;SPGF48;C2orf65;SPATA37 Full Name meiosis 1 associated protein
Status Confidence Length 90456 bases Strand Minus strand
Position 2 : 74557883 - 74648338 RNA binding domain N.A.
Summary This gene encodes a protein that is likely to function in progression of meiosis. A similar protein in mouse plays a role in gametogenesis in both sexes. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
M1AP-201 ENST00000290536 2543 530aa ENSP00000290536
M1AP-203 ENST00000421985 2544 530aa ENSP00000414882
M1AP-206 ENST00000464686 1691 No protein -
M1AP-202 ENST00000409585 2457 526aa ENSP00000386793
M1AP-209 ENST00000536235 2531 526aa ENSP00000445662
M1AP-208 ENST00000485997 277 No protein -
M1AP-205 ENST00000438226 789 93aa ENSP00000408713
M1AP-204 ENST00000422394 576 No protein -
M1AP-207 ENST00000478437 584 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
319Respiratory Function Tests3.30764630512486E-917903307
42702Platelet Function Tests2.5853062E-007-
54093Cholesterol3.1890000E-005-
90037Age-Related Hearing Impairment 19E-924939585

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003674enables molecular_function1NDHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005737located_in cytoplasm1ISSHomo_sapiens(9606)Component
GO:0006325involved_in chromatin organization1NASHomo_sapiens(9606)Process
GO:0006396involved_in RNA processing1NASHomo_sapiens(9606)Process
GO:0007127involved_in meiosis I1IEAHomo_sapiens(9606)Process
GO:0007283involved_in spermatogenesis3IBA,IMP,ISSHomo_sapiens(9606)Process
GO:0007292involved_in female gamete generation1ISSHomo_sapiens(9606)Process
GO:0016020located_in membrane1NASHomo_sapiens(9606)Component
GO:0030154involved_in cell differentiation1IEAHomo_sapiens(9606)Process
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0051308involved_in male meiosis chromosome separation2IBA,ISSHomo_sapiens(9606)Process

Expression