Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-2
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000156990 Gene ID 285367 Accession 28437
Symbol RPUSD3 Alias NA Full Name RNA pseudouridine synthase D3
Status Confidence Length 6160 bases Strand Minus strand
Position 3 : 9837849 - 9844008 RNA binding domain PseudoU_synth_2
Summary This gene encodes a protein that functions in the assembly of the mitochondrial ribosome by adding a pseudouridine group to 16S rRNA. Loss of this gene results in causes defects in mitochondrial protein production. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2017]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000373331 PseudoU_synth_2 PF00849 1.8e-19 1
ENSP00000415616 PseudoU_synth_2 PF00849 4e-19 1
ENSP00000408693 PseudoU_synth_2 PF00849 4.3e-18 1
ENSP00000398921 PseudoU_synth_2 PF00849 5.9e-15 1
ENSP00000400397 PseudoU_synth_2 PF00849 3e-12 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
RPUSD3-203 ENST00000423108 756 144aa ENSP00000405054
RPUSD3-201 ENST00000383820 1217 343aa ENSP00000373331
RPUSD3-206 ENST00000433535 1172 328aa ENSP00000398921
RPUSD3-211 ENST00000464783 1149 No protein -
RPUSD3-212 ENST00000466141 996 No protein -
RPUSD3-204 ENST00000424438 1005 212aa ENSP00000408693
RPUSD3-205 ENST00000427174 907 280aa ENSP00000400397
RPUSD3-215 ENST00000475470 2413 No protein -
RPUSD3-216 ENST00000484134 2491 No protein -
RPUSD3-202 ENST00000418713 961 242aa ENSP00000415616
RPUSD3-213 ENST00000472381 823 No protein -
RPUSD3-208 ENST00000433972 1127 128aa ENSP00000395446
RPUSD3-207 ENST00000433555 807 102aa ENSP00000396405
RPUSD3-209 ENST00000451405 817 No protein -
RPUSD3-217 ENST00000485705 630 No protein -
RPUSD3-214 ENST00000473522 547 No protein -
RPUSD3-210 ENST00000460909 578 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000156990homo_sapiensENSP0000032328822.201812.6606homo_sapiensENSP0000037333135.27720.1166
ENSG00000156990homo_sapiensENSP0000029831739.257323.6074homo_sapiensENSP0000037333143.148725.9475
ENSG00000156990homo_sapiensENSP0000000726430.769219.2308homo_sapiensENSP0000037333127.988317.4927

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000156990homo_sapiensENSP0000037333182.215781.0496nomascus_leucogenysENSNLEP0000000509993.687792.3588
ENSG00000156990homo_sapiensENSP0000037333197.959297.9592pan_paniscusENSPPAP0000003015795.726595.7265
ENSG00000156990homo_sapiensENSP0000037333197.084596.2099pongo_abeliiENSPPYP0000001529095.142994.2857
ENSG00000156990homo_sapiensENSP0000037333197.959297.9592pan_troglodytesENSPTRP0000007857395.726595.7265
ENSG00000156990homo_sapiensENSP0000037333199.125499.1254gorilla_gorillaENSGGOP0000001279996.866196.8661
ENSG00000156990homo_sapiensENSP0000037333161.807648.3965ornithorhynchus_anatinusENSOANP0000001913065.230851.0769
ENSG00000156990homo_sapiensENSP0000037333169.970855.6851sarcophilus_harrisiiENSSHAP0000001830369.364255.2023
ENSG00000156990homo_sapiensENSP0000037333158.30950.1458notamacropus_eugeniiENSMEUP0000001194777.82166.9261
ENSG00000156990homo_sapiensENSP0000037333146.647243.1487choloepus_hoffmanniENSCHOP0000000898960.836556.2738
ENSG00000156990homo_sapiensENSP0000037333183.96577.8426dasypus_novemcinctusENSDNOP0000003132176.190570.6349
ENSG00000156990homo_sapiensENSP0000037333166.763857.1429erinaceus_europaeusENSEEUP0000000670564.689355.3672
ENSG00000156990homo_sapiensENSP0000037333180.466573.4694echinops_telfairiENSETEP0000000531178.18771.3881
ENSG00000156990homo_sapiensENSP0000037333181.049675.8018callithrix_jacchusENSCJAP0000008478569.849265.3266
ENSG00000156990homo_sapiensENSP0000037333144.023338.1924callithrix_jacchusENSCJAP0000008463363.713155.2743
ENSG00000156990homo_sapiensENSP0000037333195.043793.0029cercocebus_atysENSCATP0000002708692.877590.8832
ENSG00000156990homo_sapiensENSP0000037333190.670687.172macaca_fascicularisENSMFAP0000005502869.111166.4444
ENSG00000156990homo_sapiensENSP0000037333186.588983.0904macaca_mulattaENSMMUP0000000472283.193379.8319
ENSG00000156990homo_sapiensENSP0000037333194.460692.4198macaca_nemestrinaENSMNEP0000003421192.307790.3134
ENSG00000156990homo_sapiensENSP0000037333194.752293.0029papio_anubisENSPANP0000001818892.592690.8832
ENSG00000156990homo_sapiensENSP0000037333194.752293.0029mandrillus_leucophaeusENSMLEP0000001946992.592690.8832
ENSG00000156990homo_sapiensENSP0000037333187.463680.758tursiops_truncatusENSTTRP0000000713785.227378.6932
ENSG00000156990homo_sapiensENSP0000037333188.338281.9242vulpes_vulpesENSVVUP0000003277688.081481.686
ENSG00000156990homo_sapiensENSP0000037333179.883472.5947mus_spretusMGP_SPRETEiJ_P007848479.651272.3837
ENSG00000156990homo_sapiensENSP0000037333183.673575.8018equus_asinusENSEASP0000504262477.777870.4607
ENSG00000156990homo_sapiensENSP0000037333185.714381.0496capra_hircusENSCHIP0000003181088.288383.4835
ENSG00000156990homo_sapiensENSP0000037333188.338281.3411loxodonta_africanaENSLAFP0000001467588.081481.1047
ENSG00000156990homo_sapiensENSP0000037333188.046682.2157panthera_leoENSPLOP0000000637485.795580.1136
ENSG00000156990homo_sapiensENSP0000037333187.755180.758ailuropoda_melanoleucaENSAMEP0000001713385.511478.6932
ENSG00000156990homo_sapiensENSP0000037333187.17281.6327bos_indicus_hybridENSBIXP0000502534985.185279.7721
ENSG00000156990homo_sapiensENSP0000037333158.30949.5627oryctolagus_cuniculusENSOCUP0000002181846.08339.1705
ENSG00000156990homo_sapiensENSP0000037333187.755182.2157equus_caballusENSECAP0000006542283.611178.3333
ENSG00000156990homo_sapiensENSP0000037333188.046681.0496canis_lupus_familiarisENSCAFP0084501224085.795578.9773
ENSG00000156990homo_sapiensENSP0000037333187.463681.3411panthera_pardusENSPPRP0000000100685.227379.2614
ENSG00000156990homo_sapiensENSP0000037333186.880576.9679marmota_marmota_marmotaENSMMMP0000001022386.627976.7442
ENSG00000156990homo_sapiensENSP0000037333189.212882.7988balaenoptera_musculusENSBMSP0001001075886.931880.6818
ENSG00000156990homo_sapiensENSP0000037333176.967968.2216cavia_porcellusENSCPOP0000002419974.366265.9155
ENSG00000156990homo_sapiensENSP0000037333186.880581.3411felis_catusENSFCAP0000001317384.659179.2614
ENSG00000156990homo_sapiensENSP0000037333182.215774.9271ursus_americanusENSUAMP0000001413287.850580.0623
ENSG00000156990homo_sapiensENSP0000037333168.221654.2274monodelphis_domesticaENSMODP0000000641762.06949.3369
ENSG00000156990homo_sapiensENSP0000037333187.463681.9242bison_bison_bisonENSBBBP0000001089485.470180.057
ENSG00000156990homo_sapiensENSP0000037333189.212882.7988monodon_monocerosENSMMNP0001501448286.931880.6818
ENSG00000156990homo_sapiensENSP0000037333189.212881.9242sus_scrofaENSSSCP0000001231386.931879.8295
ENSG00000156990homo_sapiensENSP0000037333188.338282.2157microcebus_murinusENSMICP0000000211388.081481.9767
ENSG00000156990homo_sapiensENSP0000037333169.387862.6822octodon_degusENSODEP0000002479383.802875.7042
ENSG00000156990homo_sapiensENSP0000037333181.632772.8863jaculus_jaculusENSJJAP0000000856181.395372.6744
ENSG00000156990homo_sapiensENSP0000037333187.463682.5073ovis_aries_rambouilletENSOARP0002003263885.470180.6268
ENSG00000156990homo_sapiensENSP0000037333187.755180.1749ursus_maritimusENSUMAP0000002584185.511478.125
ENSG00000156990homo_sapiensENSP0000037333171.13763.5569ochotona_princepsENSOPRP0000000213169.515762.1083
ENSG00000156990homo_sapiensENSP0000037333189.795983.3819delphinapterus_leucasENSDLEP0000001783687.581.25
ENSG00000156990homo_sapiensENSP0000037333189.212882.5073physeter_catodonENSPCTP0000501970887.179580.6268
ENSG00000156990homo_sapiensENSP0000037333180.466572.5947mus_caroliMGP_CAROLIEiJ_P007541780.232672.3837
ENSG00000156990homo_sapiensENSP0000037333179.883472.8863mus_musculusENSMUSP0000010871579.651272.6744
ENSG00000156990homo_sapiensENSP0000037333167.9364.723dipodomys_ordiiENSDORP0000002225881.184777.3519
ENSG00000156990homo_sapiensENSP0000037333187.463679.5918mustela_putorius_furoENSMPUP0000001702385.227377.5568
ENSG00000156990homo_sapiensENSP0000037333157.142952.1866aotus_nancymaaeENSANAP0000000086873.134366.791
ENSG00000156990homo_sapiensENSP0000037333150.145846.9388aotus_nancymaaeENSANAP0000004166782.692377.4038
ENSG00000156990homo_sapiensENSP0000037333157.725953.3528aotus_nancymaaeENSANAP0000000382479.518173.494
ENSG00000156990homo_sapiensENSP0000037333192.128388.3382saimiri_boliviensis_boliviensisENSSBOP0000004021790.804687.069
ENSG00000156990homo_sapiensENSP0000037333194.169192.1283chlorocebus_sabaeusENSCSAP0000000669992.022890.0285
ENSG00000156990homo_sapiensENSP0000037333171.13764.1399tupaia_belangeriENSTBEP0000000015184.722276.3889
ENSG00000156990homo_sapiensENSP0000037333181.924274.0525mesocricetus_auratusENSMAUP0000001627981.68673.8372
ENSG00000156990homo_sapiensENSP0000037333189.504483.0904phocoena_sinusENSPSNP0000002447987.215980.9659
ENSG00000156990homo_sapiensENSP0000037333189.212882.5073camelus_dromedariusENSCDRP0000501667783.835677.5342
ENSG00000156990homo_sapiensENSP0000037333184.548179.8834carlito_syrichtaENSTSYP0000003006383.333378.7356
ENSG00000156990homo_sapiensENSP0000037333188.338282.5073panthera_tigris_altaicaENSPTIP0000000428888.081482.2674
ENSG00000156990homo_sapiensENSP0000037333175.510268.5131rattus_norvegicusENSRNOP0000005950380.937573.4375
ENSG00000156990homo_sapiensENSP0000037333188.629784.8397prolemur_simusENSPSMP0000001333486.609782.906
ENSG00000156990homo_sapiensENSP0000037333181.341172.3032microtus_ochrogasterENSMOCP0000002697081.104772.093
ENSG00000156990homo_sapiensENSP0000037333181.341173.1778peromyscus_maniculatus_bairdiiENSPEMP0000001875281.104772.9651
ENSG00000156990homo_sapiensENSP0000037333187.463681.9242bos_mutusENSBMUP0000001490885.470180.057
ENSG00000156990homo_sapiensENSP0000037333179.591872.3032mus_spicilegusENSMSIP0000003196363.78557.9439
ENSG00000156990homo_sapiensENSP0000037333181.049672.3032cricetulus_griseus_chok1gshdENSCGRP0000100395476.795668.5083
ENSG00000156990homo_sapiensENSP0000037333186.588980.4665pteropus_vampyrusENSPVAP0000001047184.37578.4091
ENSG00000156990homo_sapiensENSP0000037333190.087583.965myotis_lucifugusENSMLUP0000000560288.793182.7586
ENSG00000156990homo_sapiensENSP0000037333170.553957.4344vombatus_ursinusENSVURP0001001435371.176557.9412
ENSG00000156990homo_sapiensENSP0000037333186.588977.8426rhinolophus_ferrumequinumENSRFEP0001002001958.811952.8713
ENSG00000156990homo_sapiensENSP0000037333186.297477.551neovison_visonENSNVIP0000001887259.79853.7374
ENSG00000156990homo_sapiensENSP0000037333187.17281.6327bos_taurusENSBTAP0000001047886.918681.3953
ENSG00000156990homo_sapiensENSP0000037333179.591872.3032heterocephalus_glaber_femaleENSHGLP0000001635770.179963.7532
ENSG00000156990homo_sapiensENSP0000037333194.169192.4198rhinopithecus_bietiENSRBIP0000003512692.022890.3134
ENSG00000156990homo_sapiensENSP0000037333188.046681.0496canis_lupus_dingoENSCAFP0002001058185.795578.9773
ENSG00000156990homo_sapiensENSP0000037333185.422777.2595sciurus_vulgarisENSSVLP0000503148483.475875.4986
ENSG00000156990homo_sapiensENSP0000037333165.889254.519phascolarctos_cinereusENSPCIP0000002943473.856261.1111
ENSG00000156990homo_sapiensENSP0000037333155.976749.8542procavia_capensisENSPCAP0000001282266.43659.1696
ENSG00000156990homo_sapiensENSP0000037333181.632773.4694nannospalax_galiliENSNGAP0000002590483.582175.2239
ENSG00000156990homo_sapiensENSP0000037333187.463681.9242bos_grunniensENSBGRP0000001705785.470180.057
ENSG00000156990homo_sapiensENSP0000037333159.183750.7289chinchilla_lanigeraENSCLAP0000000455664.649755.414
ENSG00000156990homo_sapiensENSP0000037333186.880581.6327cervus_hanglu_yarkandensisENSCHYP0000002731484.659179.5455
ENSG00000156990homo_sapiensENSP0000037333187.17280.4665catagonus_wagneriENSCWAP0000002891684.943278.4091
ENSG00000156990homo_sapiensENSP0000037333187.755178.4257ictidomys_tridecemlineatusENSSTOP0000000188885.511476.4205
ENSG00000156990homo_sapiensENSP0000037333182.507377.8426otolemur_garnettiiENSOGAP0000001128190.127485.0318
ENSG00000156990homo_sapiensENSP0000037333192.128388.9213cebus_imitatorENSCCAP0000002349990.804687.6437
ENSG00000156990homo_sapiensENSP0000037333187.463678.1341urocitellus_parryiiENSUPAP0001002908487.209377.907
ENSG00000156990homo_sapiensENSP0000037333187.17281.3411moschus_moschiferusENSMMSP0000003205484.943279.2614
ENSG00000156990homo_sapiensENSP0000037333194.169192.4198rhinopithecus_roxellanaENSRROP0000004007783.033481.491
ENSG00000156990homo_sapiensENSP0000037333181.049673.4694mus_pahariMGP_PahariEiJ_P005161680.81473.2558
ENSG00000156990homo_sapiensENSP0000037333190.37986.8805propithecus_coquereliENSPCOP0000001340988.068284.6591
ENSG00000156990homo_sapiensENSP0000037333129.737616.6181caenorhabditis_elegansZK287.7.126.356614.7287
ENSG00000156990homo_sapiensENSP0000037333136.734723.9067ciona_intestinalisENSCINP0000000776037.168124.1888
ENSG00000156990homo_sapiensENSP0000037333139.067126.2391eptatretus_burgeriENSEBUP0000002529843.790829.4118
ENSG00000156990homo_sapiensENSP0000037333140.524828.863callorhinchus_miliiENSCMIP0000002857761.233543.6123
ENSG00000156990homo_sapiensENSP0000037333118.367313.7026latimeria_chalumnaeENSLACP0000000713962.376246.5347
ENSG00000156990homo_sapiensENSP0000037333160.641444.3149xenopus_tropicalisENSXETP0000005080650.363236.8039
ENSG00000156990homo_sapiensENSP0000037333152.186642.5656chrysemys_picta_belliiENSCPBP0000001159368.582455.9387
ENSG00000156990homo_sapiensENSP0000037333126.822222.1574sphenodon_punctatusENSSPUP0000002109265.714354.2857
ENSG00000156990homo_sapiensENSP0000037333149.271141.1079crocodylus_porosusENSCPRP0000502437142.144635.1621
ENSG00000156990homo_sapiensENSP0000037333163.265344.0233laticauda_laticaudataENSLLTP0000002346853.448337.1921
ENSG00000156990homo_sapiensENSP0000037333154.51939.6501notechis_scutatusENSNSUP0000000558170.56651.3208
ENSG00000156990homo_sapiensENSP0000037333159.183742.2741pseudonaja_textilisENSPTXP0000001864566.996747.8548
ENSG00000156990homo_sapiensENSP0000037333155.976742.2741gallus_gallusENSGALP0001003150761.736346.6238
ENSG00000156990homo_sapiensENSP0000037333141.399431.7784parus_majorENSPMJP0000000558459.663945.7983
ENSG00000156990homo_sapiensENSP0000037333162.682248.9796anolis_carolinensisENSACAP0000000963661.253647.8632
ENSG00000156990homo_sapiensENSP0000037333137.317826.5306naja_najaENSNNAP0000000184670.329750
ENSG00000156990homo_sapiensENSP0000037333163.265348.688podarcis_muralisENSPMRP0000003055864.011849.2625
ENSG00000156990homo_sapiensENSP0000037333147.521936.1516geospiza_fortisENSGFOP0000000993461.742446.9697
ENSG00000156990homo_sapiensENSP0000037333153.061241.691taeniopygia_guttataENSTGUP0000000900662.54349.1409
ENSG00000156990homo_sapiensENSP0000037333148.68831.4869erpetoichthys_calabaricusENSECRP0000003345154.220835.0649
ENSG00000156990homo_sapiensENSP0000037333163.265346.9388salvator_merianaeENSSMRP0000002120663.450347.076
ENSG00000156990homo_sapiensENSP0000037333160.349948.105gopherus_evgoodeiENSGEVP0000501483964.48651.4019
ENSG00000156990homo_sapiensENSP0000037333136.443127.9883chelonoidis_abingdoniiENSCABP0000000770357.339544.0367
ENSG00000156990homo_sapiensENSP0000037333153.644342.2741strigops_habroptilaENSSHBP0000501203561.538548.495
ENSG00000156990homo_sapiensENSP0000037333158.017547.2303terrapene_carolina_triunguisENSTMTP0000002578162.382450.7837
ENSG00000156990homo_sapiensENSP0000037333125.947521.8659terrapene_carolina_triunguisENSTMTP0000002558759.731550.3356
ENSG00000156990homo_sapiensENSP0000037333119.533510.4956hucho_huchoENSHHUP0000002184621.069211.3208
ENSG00000156990homo_sapiensENSP0000037333119.533511.3703oncorhynchus_tshawytschaENSOTSP0000503881019.420311.3043
ENSG00000156990homo_sapiensENSP0000037333131.195317.2012oncorhynchus_tshawytschaENSOTSP0000503872233.024718.2099
ENSG00000156990homo_sapiensENSP0000037333154.227441.9825aquila_chrysaetos_chrysaetosENSACCP0002001501961.184247.3684
ENSG00000156990homo_sapiensENSP0000037333151.020439.0671ficedula_albicollisENSFALP0000002030060.344846.2069
ENSG00000156990homo_sapiensENSP0000037333159.475242.2741leptobrachium_leishanenseENSLLEP0000004455656.509740.1662

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001522involved_in pseudouridine synthesis1IEAHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005739located_in mitochondrion1IDAHomo_sapiens(9606)Component
GO:0005759located_in mitochondrial matrix1IEAHomo_sapiens(9606)Component
GO:0006397involved_in mRNA processing1IEAHomo_sapiens(9606)Process
GO:0009982enables pseudouridine synthase activity1IEAHomo_sapiens(9606)Function
GO:0035770located_in ribonucleoprotein granule1IDAHomo_sapiens(9606)Component
GO:0070131involved_in positive regulation of mitochondrial translation1IMPHomo_sapiens(9606)Process

Expression