Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases SARS-COV-2Dengue
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq

Description

Ensembl ID ENSG00000155959 Gene ID 7411 Accession 12662
Symbol VBP1 Alias PFD3;PFDN3;VBP-1;HIBBJ46 Full Name VHL binding protein 1
Status Confidence Length 42835 bases Strand Plus strand
Position X : 155197007 - 155239841 RNA binding domain N.A.
Summary The protein encoded by this gene interacts with the Von Hippel-Lindau protein to form an intracellular complex. The encoded protein functions as a chaperone protein, and may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. Alternative splicing and the use of alternate transcription start sites results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Jan 2015]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
VBP1-203 ENST00000535916 944 192aa ENSP00000438694
VBP1-201 ENST00000286428 1616 197aa ENSP00000286428
VBP1-202 ENST00000460509 586 No protein -
VBP1-204 ENST00000625964 1547 192aa ENSP00000486053

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001540enables amyloid-beta binding1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IEAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm1IBAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0005844part_of polysome1IBAHomo_sapiens(9606)Component
GO:0006457involved_in protein folding1IDAHomo_sapiens(9606)Process
GO:0007017involved_in microtubule-based process1IBAHomo_sapiens(9606)Process
GO:0007021involved_in tubulin complex assembly1IBAHomo_sapiens(9606)Process
GO:0015631enables tubulin binding1IBAHomo_sapiens(9606)Function
GO:0016272part_of prefoldin complex3IBA,IDA,NASHomo_sapiens(9606)Component
GO:0043231located_in intracellular membrane-bounded organelle1IDAHomo_sapiens(9606)Component
GO:0050821involved_in protein stabilization1NASHomo_sapiens(9606)Process
GO:0051082enables unfolded protein binding1IDAHomo_sapiens(9606)Function
GO:1905907involved_in negative regulation of amyloid fibril formation1IDAHomo_sapiens(9606)Process

Expression