Functions and Diseases

RBP Type Canonical_RBPs
Diseases SARS-COV-OC43FlavivirusesRVSARS-COV-2SINVDengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq DataSet_01_25 DataSet_01_36

Description

Ensembl ID ENSG00000151923 Gene ID 7073 Accession 11804
Symbol TIAL1 Alias TCBP;TIAR Full Name TIA1 cytotoxic granule associated RNA binding protein like 1
Status Confidence Length 25228 bases Strand Minus strand
Position 10 : 119571802 - 119597029 RNA binding domain RRM_1
Summary The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000394902 RRM_1 PF00076 2.4e-62 1
ENSP00000394902 RRM_1 PF00076 2.4e-62 2
ENSP00000394902 RRM_1 PF00076 2.4e-62 3
ENSP00000358089 RRM_1 PF00076 4.1e-59 1
ENSP00000358089 RRM_1 PF00076 4.1e-59 2
ENSP00000358089 RRM_1 PF00076 4.1e-59 3
ENSP00000358089 RRM_1 PF00076 4.1e-59 4
ENSP00000403573 RRM_1 PF00076 1.1e-32 1
ENSP00000403573 RRM_1 PF00076 1.1e-32 2
ENSP00000431009 RRM_1 PF00076 2.4e-28 1
ENSP00000431009 RRM_1 PF00076 2.4e-28 2
ENSP00000358082 RRM_1 PF00076 1.5e-15 1
ENSP00000358082 RRM_1 PF00076 1.5e-15 2

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
19819975 Characterization of conserved tandem donor sites and intronic motifs required for alternative splicing in corticosteroid receptor genes. Caroline Rivers 2009-11-01 Endocrinology
34789764 DHX15-independent roles for TFIP11 in U6 snRNA modification, U4/U6.U5 tri-snRNP assembly and pre-mRNA splicing fidelity. Amandine Duchemin 2021-11-17 Nature communications
37474714 The RNA binding proteins TIA1 and TIAL1 promote Mcl1 mRNA translation to protect germinal center responses from apoptosis. C Ines Osma-Garcia 2023-09-01 Cellular & molecular immunology
21048981 iCLIP predicts the dual splicing effects of TIA-RNA interactions. Zhen Wang 2010-10-26 PLoS biology
35887183 T-Cell Intracellular Antigen 1-Like Protein in Physiology and Pathology. Ramos Beatriz Velasco 2022-07-16 International journal of molecular sciences
29429924 The TIA1 RNA-Binding Protein Family Regulates EIF2AK2-Mediated Stress Response and Cell Cycle Progression. Cindy Meyer 2018-02-15 Molecular cell
36543128 The splicing regulators TIA1 and TIAL1 are required for the expression of the DNA damage repair machinery during B cell lymphopoiesis. C Ines Osma-Garcia 2022-12-20 Cell reports
29724989 Role of Hypoxia-Inducible Factors 1α (HIF1α) in SH-SY5Y Cell Autophagy Induced by Oxygen-Glucose Deprivation. Guohui Niu 2018-05-04 Medical science monitor : international medical journal of experimental and clinical research
37609036 Analysis of mRNA m6A modification and mRNA expression profiles in middle ear cholesteatoma. Shumin Xie 2023-01-01 Frontiers in genetics
32312513 A primate perspective on oocytes and transgenerational PCOS. A Daniel Dumesic 2020-06-01 Reproductive biomedicine online
32310267 Animal Models to Understand the Etiology and Pathophysiology of Polycystic Ovary Syndrome. Elisabet Stener-Victorin 2020-07-01 Endocrine reviews

Transcripts

Name Transcript ID bp Protein Translation ID
TIAL1-203 ENST00000369093 5072 392aa ENSP00000358089
TIAL1-207 ENST00000463089 907 No protein -
TIAL1-211 ENST00000489822 2222 No protein -
TIAL1-213 ENST00000497671 2321 135aa ENSP00000431009
TIAL1-209 ENST00000470781 1727 No protein -
TIAL1-205 ENST00000436547 3827 375aa ENSP00000394902
TIAL1-202 ENST00000369087 1566 No protein -
TIAL1-212 ENST00000495821 372 No protein -
TIAL1-208 ENST00000470635 336 No protein -
TIAL1-204 ENST00000412524 515 132aa ENSP00000403573
TIAL1-201 ENST00000369086 490 85aa ENSP00000358082
TIAL1-206 ENST00000462373 260 No protein -
TIAL1-210 ENST00000479729 485 28aa ENSP00000480825

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
78948Antineoplastic Agents7E-727047539
78949Cell Survival7E-727047539
78950Ovarian Neoplasms7E-727047539
78951Paclitaxel7E-727047539
103715Parkinson Disease3E-1127182965

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000151923homo_sapiensENSP0000029597122.428311.8044homo_sapiensENSP0000039490235.466718.6667
ENSG00000151923homo_sapiensENSP0000030413920.918411.4796homo_sapiensENSP0000039490221.866712
ENSG00000151923homo_sapiensENSP000004174517.122774.12371homo_sapiensENSP0000039490220.266711.7333
ENSG00000151923homo_sapiensENSP0000047869133.137819.3548homo_sapiensENSP0000039490230.133317.6
ENSG00000151923homo_sapiensENSP0000044536624.362611.0482homo_sapiensENSP0000039490222.933310.4
ENSG00000151923homo_sapiensENSP0000034182631.182817.7419homo_sapiensENSP0000039490230.933317.6
ENSG00000151923homo_sapiensENSP0000035009036.562520.9375homo_sapiensENSP0000039490231.217.8667
ENSG00000151923homo_sapiensENSP0000049380536.562520.3125homo_sapiensENSP0000039490231.217.3333
ENSG00000151923homo_sapiensENSP0000037630931.216917.4603homo_sapiensENSP0000039490231.466717.6
ENSG00000151923homo_sapiensENSP0000028407331.402417.9878homo_sapiensENSP0000039490227.466715.7333
ENSG00000151923homo_sapiensENSP0000031047130.083616.156homo_sapiensENSP0000039490228.815.4667
ENSG00000151923homo_sapiensENSP0000030916628.846215.3846homo_sapiensENSP000003949022814.9333
ENSG00000151923homo_sapiensENSP0000049824822.564112.8205homo_sapiensENSP0000039490223.466713.3333
ENSG00000151923homo_sapiensENSP0000035964522.762112.7877homo_sapiensENSP0000039490223.733313.3333
ENSG00000151923homo_sapiensENSP0000040137184.45676.943homo_sapiensENSP0000039490286.933379.2
ENSG00000151923homo_sapiensENSP0000025755228.729316.8508homo_sapiensENSP0000039490227.733316.2667
ENSG00000151923homo_sapiensENSP0000028172225.703614.0713homo_sapiensENSP0000039490236.533320
ENSG00000151923homo_sapiensENSP0000035295620.956711.6173homo_sapiensENSP0000039490224.533313.6
ENSG00000151923homo_sapiensENSP0000036293644.947727.5261homo_sapiensENSP0000039490234.421.0667
ENSG00000151923homo_sapiensENSP0000031319926.197214.6479homo_sapiensENSP0000039490224.813.8667
ENSG00000151923homo_sapiensENSP0000025336321.132110.9434homo_sapiensENSP0000039490229.866715.4667
ENSG00000151923homo_sapiensENSP0000036310924.232112.9693homo_sapiensENSP0000039490237.866720.2667
ENSG00000151923homo_sapiensENSP0000031604233.114820.3279homo_sapiensENSP0000039490226.933316.5333
ENSG00000151923homo_sapiensENSP0000031819514.78877.04225homo_sapiensENSP000003949022813.3333
ENSG00000151923homo_sapiensENSP0000035110829.518116.5663homo_sapiensENSP0000039490226.133314.6667
ENSG00000151923homo_sapiensENSP0000026174111.255.20833homo_sapiensENSP0000039490228.813.3333
ENSG00000151923homo_sapiensENSP0000023307818.427511.3022homo_sapiensENSP000003949022012.2667
ENSG00000151923homo_sapiensENSP0000037212716.93558.66935homo_sapiensENSP0000039490222.411.4667
ENSG00000151923homo_sapiensENSP0000037210516.93558.66935homo_sapiensENSP0000039490222.411.4667
ENSG00000151923homo_sapiensENSP0000037248416.93558.66935homo_sapiensENSP0000039490222.411.4667
ENSG00000151923homo_sapiensENSP0000037215416.93558.66935homo_sapiensENSP0000039490222.411.4667
ENSG00000151923homo_sapiensENSP0000025083117.13718.87097homo_sapiensENSP0000039490222.666711.7333
ENSG00000151923homo_sapiensENSP0000030715517.13718.87097homo_sapiensENSP0000039490222.666711.7333
ENSG00000151923homo_sapiensENSP0000029547023.809513.8095homo_sapiensENSP0000039490226.666715.4667
ENSG00000151923homo_sapiensENSP0000046602522.558913.1313homo_sapiensENSP0000039490217.866710.4
ENSG00000151923homo_sapiensENSP0000036595036.305719.7452homo_sapiensENSP0000039490215.28.26667

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000151923homo_sapiensENSP0000039490289.066788.5333nomascus_leucogenysENSNLEP0000002902199.109898.5163
ENSG00000151923homo_sapiensENSP00000394902100100pan_paniscusENSPPAP0000004095995.663395.6633
ENSG00000151923homo_sapiensENSP00000394902100100pongo_abeliiENSPPYP0000000315695.663395.6633
ENSG00000151923homo_sapiensENSP00000394902100100pan_troglodytesENSPTRP00000039625100100
ENSG00000151923homo_sapiensENSP0000039490290.933389.3333gorilla_gorillaENSGGOP0000004648784.197582.716
ENSG00000151923homo_sapiensENSP0000039490290.933388.5333sarcophilus_harrisiiENSSHAP0000001465584.825982.5871
ENSG00000151923homo_sapiensENSP0000039490280.266779.4667notamacropus_eugeniiENSMEUP0000001196877.377976.6067
ENSG00000151923homo_sapiensENSP0000039490280.880.8choloepus_hoffmanniENSCHOP0000000875679.527679.5276
ENSG00000151923homo_sapiensENSP0000039490279.733379.7333dasypus_novemcinctusENSDNOP00000007401100100
ENSG00000151923homo_sapiensENSP0000039490296.896.8erinaceus_europaeusENSEEUP0000001082795.275695.2756
ENSG00000151923homo_sapiensENSP000003949029696echinops_telfairiENSETEP0000001647094.736894.7368
ENSG00000151923homo_sapiensENSP00000394902100100callithrix_jacchusENSCJAP0000003656795.663395.6633
ENSG00000151923homo_sapiensENSP00000394902100100cercocebus_atysENSCATP0000004248395.663395.6633
ENSG00000151923homo_sapiensENSP00000394902100100macaca_fascicularisENSMFAP00000032469100100
ENSG00000151923homo_sapiensENSP00000394902100100macaca_mulattaENSMMUP00000055530100100
ENSG00000151923homo_sapiensENSP00000394902100100macaca_nemestrinaENSMNEP0000001648795.663395.6633
ENSG00000151923homo_sapiensENSP0000039490292.891.7333papio_anubisENSPANP0000002550564.56463.8219
ENSG00000151923homo_sapiensENSP0000039490297.697.3333mandrillus_leucophaeusENSMLEP0000002122992.424292.1717
ENSG00000151923homo_sapiensENSP0000039490291.291.2tursiops_truncatusENSTTRP0000001382187.46887.468
ENSG00000151923homo_sapiensENSP00000394902100100vulpes_vulpesENSVVUP0000001504495.663395.6633
ENSG00000151923homo_sapiensENSP0000039490299.466799.2mus_spretusMGP_SPRETEiJ_P008607195.153194.898
ENSG00000151923homo_sapiensENSP00000394902100100equus_asinusENSEASP0000504907595.663395.6633
ENSG00000151923homo_sapiensENSP0000039490297.697.3333capra_hircusENSCHIP0000002309694.818694.5596
ENSG00000151923homo_sapiensENSP0000039490297.066797.0667loxodonta_africanaENSLAFP0000000284095.538195.5381
ENSG00000151923homo_sapiensENSP00000394902100100panthera_leoENSPLOP0000002988695.663395.6633
ENSG00000151923homo_sapiensENSP0000039490297.066797.0667ailuropoda_melanoleucaENSAMEP0000001068295.538195.5381
ENSG00000151923homo_sapiensENSP00000394902100100bos_indicus_hybridENSBIXP0000501653795.663395.6633
ENSG00000151923homo_sapiensENSP0000039490287.286.4oryctolagus_cuniculusENSOCUP0000004020385.602184.8168
ENSG00000151923homo_sapiensENSP0000039490297.333397.0667equus_caballusENSECAP0000004347087.5387.2902
ENSG00000151923homo_sapiensENSP00000394902100100canis_lupus_familiarisENSCAFP0084502305595.663395.6633
ENSG00000151923homo_sapiensENSP00000394902100100panthera_pardusENSPPRP0000000841895.663395.6633
ENSG00000151923homo_sapiensENSP00000394902100100marmota_marmota_marmotaENSMMMP00000000619100100
ENSG00000151923homo_sapiensENSP00000394902100100balaenoptera_musculusENSBMSP00010017965100100
ENSG00000151923homo_sapiensENSP00000394902100100felis_catusENSFCAP0000001807295.663395.6633
ENSG00000151923homo_sapiensENSP0000039490289.066788.5333ursus_americanusENSUAMP0000001192599.109898.5163
ENSG00000151923homo_sapiensENSP0000039490297.066797.0667bison_bison_bisonENSBBBP0000000104695.538195.5381
ENSG00000151923homo_sapiensENSP00000394902100100monodon_monocerosENSMMNP0001502773595.663395.6633
ENSG00000151923homo_sapiensENSP0000039490297.866797.0667sus_scrofaENSSSCP0000003307192.911492.1519
ENSG00000151923homo_sapiensENSP00000394902100100microcebus_murinusENSMICP00000021287100100
ENSG00000151923homo_sapiensENSP0000039490299.466799.4667octodon_degusENSODEP0000002424295.153195.1531
ENSG00000151923homo_sapiensENSP0000039490296.533396jaculus_jaculusENSJJAP0000000294794.270893.75
ENSG00000151923homo_sapiensENSP0000039490257.066755.4667jaculus_jaculusENSJJAP0000002252298.617595.8525
ENSG00000151923homo_sapiensENSP00000394902100100ovis_aries_rambouilletENSOARP0002001869695.663395.6633
ENSG00000151923homo_sapiensENSP00000394902100100ursus_maritimusENSUMAP00000003894100100
ENSG00000151923homo_sapiensENSP00000394902100100delphinapterus_leucasENSDLEP00000011627100100
ENSG00000151923homo_sapiensENSP00000394902100100physeter_catodonENSPCTP0000503067695.663395.6633
ENSG00000151923homo_sapiensENSP0000039490299.466799.2mus_caroliMGP_CAROLIEiJ_P008265695.153194.898
ENSG00000151923homo_sapiensENSP0000039490299.466799.2mus_musculusENSMUSP0000010183395.153194.898
ENSG00000151923homo_sapiensENSP0000039490297.866797.0667dipodomys_ordiiENSDORP0000001004389.73188.9976
ENSG00000151923homo_sapiensENSP00000394902100100mustela_putorius_furoENSMPUP00000003029100100
ENSG00000151923homo_sapiensENSP00000394902100100aotus_nancymaaeENSANAP0000003358595.663395.6633
ENSG00000151923homo_sapiensENSP00000394902100100saimiri_boliviensis_boliviensisENSSBOP0000002383195.663395.6633
ENSG00000151923homo_sapiensENSP0000039490289.689.6vicugna_pacosENSVPAP0000000114695.726595.7265
ENSG00000151923homo_sapiensENSP00000394902100100chlorocebus_sabaeusENSCSAP00000001062100100
ENSG00000151923homo_sapiensENSP0000039490250.447.2mesocricetus_auratusENSMAUP0000000719080.425575.3191
ENSG00000151923homo_sapiensENSP00000394902100100phocoena_sinusENSPSNP0000003058895.663395.6633
ENSG00000151923homo_sapiensENSP0000039490298.666798.4camelus_dromedariusENSCDRP0000502337194.871894.6154
ENSG00000151923homo_sapiensENSP0000039490297.066797.0667carlito_syrichtaENSTSYP0000000397994.791794.7917
ENSG00000151923homo_sapiensENSP00000394902100100panthera_tigris_altaicaENSPTIP0000000578795.663395.6633
ENSG00000151923homo_sapiensENSP0000039490299.466799.2rattus_norvegicusENSRNOP0000002746395.153194.898
ENSG00000151923homo_sapiensENSP00000394902100100prolemur_simusENSPSMP0000001572295.663395.6633
ENSG00000151923homo_sapiensENSP0000039490296.896.5333microtus_ochrogasterENSMOCP0000001487394.285794.026
ENSG00000151923homo_sapiensENSP0000039490296.896.8sorex_araneusENSSARP0000001172195.026295.0262
ENSG00000151923homo_sapiensENSP0000039490299.466799.2peromyscus_maniculatus_bairdiiENSPEMP0000001486995.153194.898
ENSG00000151923homo_sapiensENSP0000039490297.866797.6bos_mutusENSBMUP0000000943390.617390.3704
ENSG00000151923homo_sapiensENSP0000039490299.466799.2mus_spicilegusENSMSIP0000002851999.466799.2
ENSG00000151923homo_sapiensENSP0000039490299.466799.2cricetulus_griseus_chok1gshdENSCGRP0000101101899.466799.2
ENSG00000151923homo_sapiensENSP0000039490299.733399.7333pteropus_vampyrusENSPVAP0000001658895.408295.4082
ENSG00000151923homo_sapiensENSP0000039490298.133397.8667myotis_lucifugusENSMLUP0000000422797.872397.6064
ENSG00000151923homo_sapiensENSP0000039490295.733394.4vombatus_ursinusENSVURP0001003269191.581690.3061
ENSG00000151923homo_sapiensENSP00000394902100100rhinolophus_ferrumequinumENSRFEP0001001864395.663395.6633
ENSG00000151923homo_sapiensENSP0000039490297.066797.0667neovison_visonENSNVIP0000000650592.857192.8571
ENSG00000151923homo_sapiensENSP0000039490297.866797.6bos_taurusENSBTAP0000005981590.617390.3704
ENSG00000151923homo_sapiensENSP0000039490299.466799.4667heterocephalus_glaber_femaleENSHGLP0000001919795.153195.1531
ENSG00000151923homo_sapiensENSP0000039490294.933394.9333rhinopithecus_bietiENSRBIP0000000763090.816390.8163
ENSG00000151923homo_sapiensENSP00000394902100100canis_lupus_dingoENSCAFP00020017345100100
ENSG00000151923homo_sapiensENSP00000394902100100sciurus_vulgarisENSSVLP0000500350595.663395.6633
ENSG00000151923homo_sapiensENSP0000039490299.299.2sciurus_vulgarisENSSVLP0000502325199.299.2
ENSG00000151923homo_sapiensENSP0000039490295.733394.6667phascolarctos_cinereusENSPCIP0000004641491.581690.5612
ENSG00000151923homo_sapiensENSP0000039490299.733399.7333procavia_capensisENSPCAP0000000299195.165495.1654
ENSG00000151923homo_sapiensENSP0000039490297.866797.3333nannospalax_galiliENSNGAP0000002116793.384292.8753
ENSG00000151923homo_sapiensENSP00000394902100100bos_grunniensENSBGRP0000003425195.663395.6633
ENSG00000151923homo_sapiensENSP0000039490299.733399.7333chinchilla_lanigeraENSCLAP0000000170495.408295.4082
ENSG00000151923homo_sapiensENSP00000394902100100cervus_hanglu_yarkandensisENSCHYP0000001204456.221956.2219
ENSG00000151923homo_sapiensENSP0000039490299.733399.7333catagonus_wagneriENSCWAP0000002417695.408295.4082
ENSG00000151923homo_sapiensENSP0000039490297.697.0667ictidomys_tridecemlineatusENSSTOP0000002039993.846293.3333
ENSG00000151923homo_sapiensENSP00000394902100100otolemur_garnettiiENSOGAP0000001022595.663395.6633
ENSG00000151923homo_sapiensENSP0000039490290.133390.1333cebus_imitatorENSCCAP0000000050395.211395.2113
ENSG00000151923homo_sapiensENSP00000394902100100urocitellus_parryiiENSUPAP00010008271100100
ENSG00000151923homo_sapiensENSP0000039490242.666742.4moschus_moschiferusENSMMSP0000002451910099.375
ENSG00000151923homo_sapiensENSP00000394902100100moschus_moschiferusENSMMSP0000002297995.663395.6633
ENSG00000151923homo_sapiensENSP0000039490291.733391.4667moschus_moschiferusENSMMSP0000002523799.135498.8473
ENSG00000151923homo_sapiensENSP00000394902100100rhinopithecus_roxellanaENSRROP0000004020791.463491.4634
ENSG00000151923homo_sapiensENSP0000039490299.466799.2mus_pahariMGP_PahariEiJ_P001945295.153194.898
ENSG00000151923homo_sapiensENSP00000394902100100propithecus_coquereliENSPCOP0000001461395.663395.6633
ENSG00000151923homo_sapiensENSP0000039490293.066789.0667latimeria_chalumnaeENSLACP0000001334389.487285.641
ENSG00000151923homo_sapiensENSP0000039490295.466792xenopus_tropicalisENSXETP0000010851692.030888.6889
ENSG00000151923homo_sapiensENSP0000039490297.333396.5333chrysemys_picta_belliiENSCPBP0000000134894.072293.299
ENSG00000151923homo_sapiensENSP0000039490296.895.7333sphenodon_punctatusENSSPUP0000000311193.316292.2879
ENSG00000151923homo_sapiensENSP0000039490297.066796.2667crocodylus_porosusENSCPRP000050149399190.25
ENSG00000151923homo_sapiensENSP0000039490287.286.6667anas_platyrhynchos_platyrhynchosENSAPLP0000000882693.428692.8571
ENSG00000151923homo_sapiensENSP0000039490297.333396.8serinus_canariaENSSCAP0000001967798.382897.8437
ENSG00000151923homo_sapiensENSP0000039490294.666792.5333anolis_carolinensisENSACAP0000001675089.420787.4055
ENSG00000151923homo_sapiensENSP0000039490296.533394.6667salvator_merianaeENSSMRP0000000569693.29991.4948
ENSG00000151923homo_sapiensENSP0000039490296.266795.2gopherus_evgoodeiENSGEVP0000502822091.857590.8397
ENSG00000151923homo_sapiensENSP0000039490297.866797.0667chelonoidis_abingdoniiENSCABP0000002442594.587693.8144
ENSG00000151923homo_sapiensENSP0000039490297.333396.8anser_brachyrhynchusENSABRP0000000093398.382897.8437
ENSG00000151923homo_sapiensENSP0000039490297.333396.5333terrapene_carolina_triunguisENSTMTP0000002501494.072293.299
ENSG00000151923homo_sapiensENSP0000039490297.333396.8aquila_chrysaetos_chrysaetosENSACCP0002001101398.382897.8437
ENSG00000151923homo_sapiensENSP0000039490287.277.8667takifugu_rubripesENSTRUP0000006170472.505564.745
ENSG00000151923homo_sapiensENSP0000039490290.666784.8sinocyclocheilus_grahamiENSSGRP0000001996389.005283.2461
ENSG00000151923homo_sapiensENSP0000039490272.864.5333sinocyclocheilus_grahamiENSSGRP0000005284684.782675.1553
ENSG00000151923homo_sapiensENSP0000039490273.662.1333tetraodon_nigroviridisENSTNIP0000001607282.388169.5522
ENSG00000151923homo_sapiensENSP0000039490259.252.2667oryzias_melastigmaENSOMEP0000001526385.057575.0958

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003677enables DNA binding1IEAHomo_sapiens(9606)Function
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003730enables mRNA 3-UTR binding1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1ISSHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1ISSHomo_sapiens(9606)Component
GO:0005764located_in lysosome1TASHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0006357involved_in regulation of transcription by RNA polymerase II1TASHomo_sapiens(9606)Process
GO:0006915involved_in apoptotic process1IEAHomo_sapiens(9606)Process
GO:0006952involved_in defense response1TASHomo_sapiens(9606)Process
GO:0007281involved_in germ cell development1IEAHomo_sapiens(9606)Process
GO:0008285involved_in negative regulation of cell population proliferation1IMPHomo_sapiens(9606)Process
GO:0010494located_in cytoplasmic stress granule1ISSHomo_sapiens(9606)Component
GO:0017145involved_in stem cell division1IEAHomo_sapiens(9606)Process
GO:0035332involved_in positive regulation of hippo signaling1IMPHomo_sapiens(9606)Process
GO:0035925enables mRNA 3-UTR AU-rich region binding1IEAHomo_sapiens(9606)Function
GO:0044194located_in cytolytic granule1IEAHomo_sapiens(9606)Component
GO:0072089involved_in stem cell proliferation1IEAHomo_sapiens(9606)Process
GO:0140517enables protein-RNA adaptor activity1IDAHomo_sapiens(9606)Function
GO:2000637involved_in positive regulation of miRNA-mediated gene silencing1IGIHomo_sapiens(9606)Process
GO:2000648involved_in positive regulation of stem cell proliferation1IEAHomo_sapiens(9606)Process

Expression