Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-2DengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq DataSet_02_123

Description

Ensembl ID ENSG00000149658 Gene ID 54915 Accession 15867
Symbol YTHDF1 Alias DF1;C20orf21 Full Name YTH N6-methyladenosine RNA binding protein F1
Status Confidence Length 20711 bases Strand Minus strand
Position 20 : 63195429 - 63216139 RNA binding domain YTH
Summary Enables N6-methyladenosine-containing RNA binding activity and ribosome binding activity. Involved in mRNA destabilization; positive regulation of translational initiation; and stress granule assembly. Located in P-body and cytoplasmic stress granule. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000359364 YTH PF04146 1.2e-41 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
36291811 m6A Methyltransferase KIAA1429 Regulates the Cisplatin Sensitivity of Gastric Cancer Cells via Stabilizing FOXM1 mRNA. Zhongcheng Zhu 2022-10-14 Cancers
35319018 YTHDF1 upregulation mediates hypoxia-dependent breast cancer growth and metastasis through regulating PKM2 to affect glycolysis. Xuemei Yao 2022-03-23 Cell death & disease
31187550 Significant epitranscriptomes in heterogeneous cancer. Masamitsu Konno 2019-08-01 Cancer science
36650153 Tumor-intrinsic YTHDF1 drives immune evasion and resistance to immune checkpoint inhibitors via promoting MHC-I degradation. Wanzun Lin 2023-01-17 Nature communications
30131850 N6-methyladenosine contributes to cellular phenotype in a genetically-defined model of breast cancer progression. J Nate Fry 2018-07-27 Oncotarget
34324489 N6-methyladenosine promotes induction of ADAR1-mediated A-to-I RNA editing to suppress aberrant antiviral innate immune responses. Hideki Terajima 2021-07-01 PLoS biology
33999206 The N6-methyladenosine RNA-binding protein YTHDF1 modulates the translation of TRAF6 to mediate the intestinal immune response. Xin Zong 2021-06-04 Nucleic acids research
36717220 Targeting m6A reader YTHDF1 augments antitumour immunity and boosts anti-PD-1 efficacy in colorectal cancer. Yi Bao 2023-08-01 Gut
26159994 RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation. Yanan Yue 2015-07-01 Genes & development
28901284 Correction: N6-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression. Nagaraja Tirumuru 2017-09-13 eLife
27371828 N(6)-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression. Nagaraja Tirumuru 2016-07-02 eLife
32375856 RNA modifications in brain tumorigenesis. Z Albert Huang 2020-05-06 Acta neuropathologica communications
27773536 Dynamics of Human and Viral RNA Methylation during Zika Virus Infection. Gianluigi Lichinchi 2016-11-09 Cell host & microbe
34103492 The zinc-finger protein Red1 orchestrates MTREC submodules and binds the Mtl1 helicase arch domain. Nikolay Dobrev 2021-06-08 Nature communications

Transcripts

Name Transcript ID bp Protein Translation ID
YTHDF1-202 ENST00000370339 3198 559aa ENSP00000359364
YTHDF1-201 ENST00000370334 747 52aa ENSP00000359359

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
86633Cytarabine2E-624483146

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000149658homo_sapiensENSP0000036291874.438764.2487homo_sapiensENSP0000035936477.10266.5474
ENSG00000149658homo_sapiensENSP0000047349676.581268.2051homo_sapiensENSP0000035936480.143171.3775
ENSG00000149658homo_sapiensENSP0000033924525.722113.8927homo_sapiensENSP0000035936433.452618.068

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000149658homo_sapiensENSP000003593649.302339.12344nomascus_leucogenysENSNLEP0000004843310098.0769
ENSG00000149658homo_sapiensENSP0000035936497.674497.6744pan_paniscusENSPPAP0000000567893.493193.4931
ENSG00000149658homo_sapiensENSP0000035936499.642299.1055pongo_abeliiENSPPYP0000001254299.642299.1055
ENSG00000149658homo_sapiensENSP0000035936497.674497.6744pan_troglodytesENSPTRP0000009255893.493193.4931
ENSG00000149658homo_sapiensENSP0000035936497.674497.6744gorilla_gorillaENSGGOP0000000814793.493193.4931
ENSG00000149658homo_sapiensENSP0000035936495.706689.6243ornithorhynchus_anatinusENSOANP0000000589795.365489.3048
ENSG00000149658homo_sapiensENSP0000035936493.738887.6565sarcophilus_harrisiiENSSHAP0000001217276.720471.7423
ENSG00000149658homo_sapiensENSP0000035936493.917789.6243dasypus_novemcinctusENSDNOP0000003102893.917789.6243
ENSG00000149658homo_sapiensENSP0000035936487.298783.3632erinaceus_europaeusENSEEUP0000000677594.757390.4854
ENSG00000149658homo_sapiensENSP0000035936455.456249.195echinops_telfairiENSETEP0000001451276.732768.0693
ENSG00000149658homo_sapiensENSP0000035936495.348893.7388callithrix_jacchusENSCJAP0000007723594.169692.5795
ENSG00000149658homo_sapiensENSP0000035936499.284498.2111cercocebus_atysENSCATP0000001893299.284498.2111
ENSG00000149658homo_sapiensENSP0000035936499.284498.39macaca_fascicularisENSMFAP0000000677999.284498.39
ENSG00000149658homo_sapiensENSP0000035936499.284498.39macaca_mulattaENSMMUP0000001209199.284498.39
ENSG00000149658homo_sapiensENSP0000035936499.284498.39macaca_nemestrinaENSMNEP0000001318299.284498.39
ENSG00000149658homo_sapiensENSP0000035936498.926797.8533papio_anubisENSPANP0000005051593.570292.555
ENSG00000149658homo_sapiensENSP0000035936497.495596.2433mandrillus_leucophaeusENSMLEP0000000229496.119994.8854
ENSG00000149658homo_sapiensENSP0000035936491.234386.4043tursiops_truncatusENSTTRP0000000170192.057887.1841
ENSG00000149658homo_sapiensENSP0000035936487.298783.8998vulpes_vulpesENSVVUP0000002075295.874392.1415
ENSG00000149658homo_sapiensENSP0000035936496.422293.7388mus_spretusMGP_SPRETEiJ_P005885191.979589.4198
ENSG00000149658homo_sapiensENSP0000035936495.885592.8444equus_asinusENSEASP0000503625986.591383.8449
ENSG00000149658homo_sapiensENSP0000035936494.275588.0143capra_hircusENSCHIP0000003257194.275588.0143
ENSG00000149658homo_sapiensENSP0000035936495.706691.771loxodonta_africanaENSLAFP0000002037991.45387.6923
ENSG00000149658homo_sapiensENSP0000035936495.348892.3077panthera_leoENSPLOP0000002276295.348892.3077
ENSG00000149658homo_sapiensENSP0000035936496.243393.2021ailuropoda_melanoleucaENSAMEP0000001829696.243393.2021
ENSG00000149658homo_sapiensENSP0000035936494.454488.551bos_indicus_hybridENSBIXP0000501670294.454488.551
ENSG00000149658homo_sapiensENSP0000035936486.94180.1431oryctolagus_cuniculusENSOCUP0000002765474.539968.7117
ENSG00000149658homo_sapiensENSP0000035936494.633391.5921equus_caballusENSECAP0000008422992.644589.6673
ENSG00000149658homo_sapiensENSP0000035936496.064492.6655canis_lupus_familiarisENSCAFP0084502609096.064492.6655
ENSG00000149658homo_sapiensENSP0000035936488.372184.6154canis_lupus_familiarisENSCAFP0084502631192.164288.2463
ENSG00000149658homo_sapiensENSP0000035936495.348892.3077panthera_pardusENSPPRP0000002860295.348892.3077
ENSG00000149658homo_sapiensENSP0000035936496.601192.8444marmota_marmota_marmotaENSMMMP0000000374896.774293.0107
ENSG00000149658homo_sapiensENSP0000035936494.633389.6243balaenoptera_musculusENSBMSP0001001517994.633389.6243
ENSG00000149658homo_sapiensENSP0000035936496.601193.0233cavia_porcellusENSCPOP0000000916396.601193.0233
ENSG00000149658homo_sapiensENSP0000035936494.454490.3399felis_catusENSFCAP0000005685964.705961.8873
ENSG00000149658homo_sapiensENSP0000035936494.454490.8766ursus_americanusENSUAMP0000001371794.117690.5526
ENSG00000149658homo_sapiensENSP0000035936494.096687.6565monodelphis_domesticaENSMODP0000002102087.520881.5308
ENSG00000149658homo_sapiensENSP0000035936489.087783.1843bison_bison_bisonENSBBBP0000002313788.770182.8877
ENSG00000149658homo_sapiensENSP0000035936494.275589.6243monodon_monocerosENSMMNP0001500346494.275589.6243
ENSG00000149658homo_sapiensENSP0000035936492.128886.0465sus_scrofaENSSSCP0000006260890.509784.5343
ENSG00000149658homo_sapiensENSP0000035936497.495594.8122microcebus_murinusENSMICP0000003726897.495594.8122
ENSG00000149658homo_sapiensENSP0000035936482.647678.712octodon_degusENSODEP0000000008092.215687.8243
ENSG00000149658homo_sapiensENSP0000035936494.991191.0555octodon_degusENSODEP0000000581889.695985.9797
ENSG00000149658homo_sapiensENSP0000035936495.885593.2021jaculus_jaculusENSJJAP0000000982597.454594.7273
ENSG00000149658homo_sapiensENSP0000035936493.917787.4776ovis_aries_rambouilletENSOARP0002000642689.285783.1633
ENSG00000149658homo_sapiensENSP0000035936487.298784.4365ursus_maritimusENSUMAP0000003085895.874392.7308
ENSG00000149658homo_sapiensENSP0000035936481.93276.2075ochotona_princepsENSOPRP0000000161988.41782.2394
ENSG00000149658homo_sapiensENSP0000035936493.202189.0877delphinapterus_leucasENSDLEP0000000891789.365385.4202
ENSG00000149658homo_sapiensENSP0000035936493.023388.551physeter_catodonENSPCTP0000501354293.693789.1892
ENSG00000149658homo_sapiensENSP0000035936496.422293.7388mus_caroliMGP_CAROLIEiJ_P005663891.979589.4198
ENSG00000149658homo_sapiensENSP0000035936496.422293.7388mus_musculusENSMUSP0000010450491.979589.4198
ENSG00000149658homo_sapiensENSP0000035936493.738889.9821dipodomys_ordiiENSDORP0000000270191.448587.7836
ENSG00000149658homo_sapiensENSP0000035936484.615479.7853mustela_putorius_furoENSMPUP0000000805493.293987.9684
ENSG00000149658homo_sapiensENSP0000035936485.330983.0054aotus_nancymaaeENSANAP0000000590291.204688.7189
ENSG00000149658homo_sapiensENSP0000035936497.853396.9589aotus_nancymaaeENSANAP0000003430297.853396.9589
ENSG00000149658homo_sapiensENSP0000035936495.706693.0233saimiri_boliviensis_boliviensisENSSBOP0000002145093.695391.0683
ENSG00000149658homo_sapiensENSP0000035936499.284498.39chlorocebus_sabaeusENSCSAP0000001233899.284498.39
ENSG00000149658homo_sapiensENSP0000035936496.422293.9177mesocricetus_auratusENSMAUP0000001935396.422293.9177
ENSG00000149658homo_sapiensENSP0000035936494.454489.4454phocoena_sinusENSPSNP0000002897094.454489.4454
ENSG00000149658homo_sapiensENSP0000035936494.096688.1932camelus_dromedariusENSCDRP0000501021994.434588.5099
ENSG00000149658homo_sapiensENSP0000035936495.169992.8444carlito_syrichtaENSTSYP0000001994895.683593.3453
ENSG00000149658homo_sapiensENSP0000035936484.615481.3953panthera_tigris_altaicaENSPTIP0000001960893.849290.2778
ENSG00000149658homo_sapiensENSP0000035936496.422293.5599rattus_norvegicusENSRNOP0000003770091.979589.2491
ENSG00000149658homo_sapiensENSP0000035936496.064492.8444prolemur_simusENSPSMP0000002399287.459384.5277
ENSG00000149658homo_sapiensENSP0000035936496.064493.7388microtus_ochrogasterENSMOCP0000001391896.064493.7388
ENSG00000149658homo_sapiensENSP0000035936496.422293.9177peromyscus_maniculatus_bairdiiENSPEMP0000002302696.422293.9177
ENSG00000149658homo_sapiensENSP0000035936493.202187.2987bos_mutusENSBMUP0000003042694.727388.7273
ENSG00000149658homo_sapiensENSP0000035936495.527792.8444mus_spicilegusENSMSIP0000001725588.264585.7851
ENSG00000149658homo_sapiensENSP0000035936495.706693.2021cricetulus_griseus_chok1gshdENSCGRP0000101615592.241489.8276
ENSG00000149658homo_sapiensENSP0000035936489.087782.6476pteropus_vampyrusENSPVAP0000001657191.04284.4607
ENSG00000149658homo_sapiensENSP0000035936492.486688.3721myotis_lucifugusENSMLUP0000000203291.992987.9004
ENSG00000149658homo_sapiensENSP0000035936494.454488.0143vombatus_ursinusENSVURP0001002307692.957786.6197
ENSG00000149658homo_sapiensENSP0000035936491.413286.5832rhinolophus_ferrumequinumENSRFEP0001002520091.577186.7383
ENSG00000149658homo_sapiensENSP0000035936488.55182.6476neovison_visonENSNVIP0000002559888.55182.6476
ENSG00000149658homo_sapiensENSP0000035936494.633388.7299bos_taurusENSBTAP0000001370394.633388.7299
ENSG00000149658homo_sapiensENSP0000035936496.958994.0966heterocephalus_glaber_femaleENSHGLP0000000916597.48294.6043
ENSG00000149658homo_sapiensENSP0000035936497.853396.2433rhinopithecus_bietiENSRBIP0000004359997.504595.9002
ENSG00000149658homo_sapiensENSP0000035936487.477684.2576canis_lupus_dingoENSCAFP0002000133396.070792.5344
ENSG00000149658homo_sapiensENSP0000035936497.316693.9177sciurus_vulgarisENSSVLP0000500487097.316693.9177
ENSG00000149658homo_sapiensENSP0000035936494.275587.8354phascolarctos_cinereusENSPCIP0000002263589.931783.7884
ENSG00000149658homo_sapiensENSP0000035936484.078778.3542procavia_capensisENSPCAP0000000225792.702286.3905
ENSG00000149658homo_sapiensENSP0000035936497.137794.0966nannospalax_galiliENSNGAP0000000042097.137794.0966
ENSG00000149658homo_sapiensENSP000003593649.123448.94454bos_grunniensENSBGRP0000003085598.076996.1538
ENSG00000149658homo_sapiensENSP0000035936495.527792.8444chinchilla_lanigeraENSCLAP0000000856890.97188.4157
ENSG00000149658homo_sapiensENSP0000035936494.275587.6565cervus_hanglu_yarkandensisENSCHYP0000003634582.731676.9231
ENSG00000149658homo_sapiensENSP0000035936492.128885.1521catagonus_wagneriENSCWAP0000002162592.293985.3047
ENSG00000149658homo_sapiensENSP0000035936496.243392.8444ictidomys_tridecemlineatusENSSTOP0000001957297.463894.0217
ENSG00000149658homo_sapiensENSP0000035936496.064492.8444otolemur_garnettiiENSOGAP0000000043196.064492.8444
ENSG00000149658homo_sapiensENSP0000035936497.674496.2433cebus_imitatorENSCCAP0000001367093.333391.9658
ENSG00000149658homo_sapiensENSP0000035936496.243392.3077urocitellus_parryiiENSUPAP0001001204290.725187.0152
ENSG00000149658homo_sapiensENSP0000035936494.454487.8354moschus_moschiferusENSMMSP0000002853794.454487.8354
ENSG00000149658homo_sapiensENSP0000035936497.853396.0644rhinopithecus_roxellanaENSRROP0000001786597.504595.7219
ENSG00000149658homo_sapiensENSP0000035936496.422293.5599mus_pahariMGP_PahariEiJ_P006764696.422293.5599
ENSG00000149658homo_sapiensENSP0000035936497.853395.1699propithecus_coquereliENSPCOP0000002705397.853395.1699
ENSG00000149658homo_sapiensENSP0000035936449.19536.8515drosophila_melanogasterFBpp008416939.285729.4286
ENSG00000149658homo_sapiensENSP0000035936458.676246.1538ciona_intestinalisENSCINP0000000861057.342745.1049
ENSG00000149658homo_sapiensENSP0000035936489.624382.1109callorhinchus_miliiENSCMIP0000002781483.919676.8844
ENSG00000149658homo_sapiensENSP0000035936488.014382.8265latimeria_chalumnaeENSLACP0000001611688.808783.574
ENSG00000149658homo_sapiensENSP0000035936488.014380.5009lepisosteus_oculatusENSLOCP0000000604484.827677.5862
ENSG00000149658homo_sapiensENSP0000035936485.152177.2809clupea_harengusENSCHAP0000004125676.282169.2308
ENSG00000149658homo_sapiensENSP0000035936484.078776.2075clupea_harengusENSCHAP0000004514867.238960.9442
ENSG00000149658homo_sapiensENSP0000035936485.330977.9964danio_rerioENSDARP0000000574677.687371.0098
ENSG00000149658homo_sapiensENSP0000035936484.257676.0286carassius_auratusENSCARP0000012875673.940366.719
ENSG00000149658homo_sapiensENSP0000035936484.794376.9231carassius_auratusENSCARP0000012405471.064564.4678
ENSG00000149658homo_sapiensENSP0000035936485.330978.3542carassius_auratusENSCARP0000001842178.068771.6858
ENSG00000149658homo_sapiensENSP0000035936485.330978.3542carassius_auratusENSCARP0000012403678.068771.6858
ENSG00000149658homo_sapiensENSP0000035936484.615476.2075ictalurus_punctatusENSIPUP0000000056077.54169.8361
ENSG00000149658homo_sapiensENSP0000035936482.468776.0286esox_luciusENSELUP0000002613169.323363.9098
ENSG00000149658homo_sapiensENSP0000035936486.225478.1753esox_luciusENSELUP0000004178077.867570.5977
ENSG00000149658homo_sapiensENSP0000035936481.216574.7764electrophorus_electricusENSEEEP0000003382577.606871.453
ENSG00000149658homo_sapiensENSP0000035936481.574274.9553oncorhynchus_kisutchENSOKIP0000504809273.311967.3633
ENSG00000149658homo_sapiensENSP0000035936454.740650.6261oncorhynchus_kisutchENSOKIP0000511572273.205767.7033
ENSG00000149658homo_sapiensENSP0000035936485.509877.6386oncorhynchus_kisutchENSOKIP0000508689978.877971.6172
ENSG00000149658homo_sapiensENSP0000035936482.468774.0608oncorhynchus_kisutchENSOKIP0000502477668.601261.6071
ENSG00000149658homo_sapiensENSP0000035936481.753174.9553oncorhynchus_mykissENSOMYP0000011212571.294965.3666
ENSG00000149658homo_sapiensENSP0000035936484.257676.3864oncorhynchus_mykissENSOMYP0000013858576.46169.3182
ENSG00000149658homo_sapiensENSP0000035936484.794376.9231oncorhynchus_mykissENSOMYP0000002948777.198770.0326
ENSG00000149658homo_sapiensENSP0000035936481.037674.0608salmo_salarENSSSAP0000013997279.894273.0159
ENSG00000149658homo_sapiensENSP0000035936479.069873.5241salmo_salarENSSSAP0000000156177.680172.232
ENSG00000149658homo_sapiensENSP0000035936484.794377.9964salmo_salarENSSSAP0000004776475.961569.8718
ENSG00000149658homo_sapiensENSP0000035936483.899876.3864salmo_salarENSSSAP0000015771475.0468.32
ENSG00000149658homo_sapiensENSP0000035936484.078776.2075salmo_truttaENSSTUP0000002616977.68670.4132
ENSG00000149658homo_sapiensENSP0000035936484.794376.7442salmo_truttaENSSTUP0000002902277.198769.8697
ENSG00000149658homo_sapiensENSP0000035936483.184377.102salmo_truttaENSSTUP0000003392269.610864.521
ENSG00000149658homo_sapiensENSP0000035936484.794377.9964salmo_truttaENSSTUP0000008220776.083569.9839
ENSG00000149658homo_sapiensENSP0000035936484.794375.1342gadus_morhuaENSGMOP0000002336274.763466.2461
ENSG00000149658homo_sapiensENSP0000035936483.363275.8497gadus_morhuaENSGMOP0000003698174.203867.5159
ENSG00000149658homo_sapiensENSP0000035936484.436577.4597fundulus_heteroclitusENSFHEP0000000178976.375470.0647
ENSG00000149658homo_sapiensENSP0000035936482.468773.703fundulus_heteroclitusENSFHEP0000003517475.203967.2104
ENSG00000149658homo_sapiensENSP0000035936482.468775.6708poecilia_reticulataENSPREP0000002613475.573869.3443
ENSG00000149658homo_sapiensENSP0000035936482.647674.0608poecilia_reticulataENSPREP0000000298175.862167.9803
ENSG00000149658homo_sapiensENSP0000035936485.152177.8175xiphophorus_maculatusENSXMAP0000001567977.147570.5024
ENSG00000149658homo_sapiensENSP0000035936482.468774.0608xiphophorus_maculatusENSXMAP0000000854076.198368.4297
ENSG00000149658homo_sapiensENSP0000035936482.110973.5241oryzias_latipesENSORLP0000001838275.245967.3771
ENSG00000149658homo_sapiensENSP0000035936484.257676.9231oryzias_latipesENSORLP0000001221876.960870.2614
ENSG00000149658homo_sapiensENSP0000035936483.363276.2075cyclopterus_lumpusENSCLMP0000501991474.203867.8344
ENSG00000149658homo_sapiensENSP0000035936481.753175.1342cyclopterus_lumpusENSCLMP0000501423176.166770
ENSG00000149658homo_sapiensENSP0000035936484.615477.6386oreochromis_niloticusENSONIP0000004184376.785770.4545
ENSG00000149658homo_sapiensENSP0000035936482.289873.703oreochromis_niloticusENSONIP0000002116973.248465.6051
ENSG00000149658homo_sapiensENSP0000035936484.615477.6386haplochromis_burtoniENSHBUP0000002384076.785770.4545
ENSG00000149658homo_sapiensENSP0000035936483.363274.7764haplochromis_burtoniENSHBUP0000002783773.385865.8268
ENSG00000149658homo_sapiensENSP0000035936484.436577.8175astatotilapia_callipteraENSACLP0000003772276.623470.6169
ENSG00000149658homo_sapiensENSP0000035936485.330978.5331sparus_aurataENSSAUP0001003925477.184571.0356
ENSG00000149658homo_sapiensENSP0000035936482.647674.9553sparus_aurataENSSAUP0001002747372.870766.0883
ENSG00000149658homo_sapiensENSP0000035936483.184376.0286lates_calcariferENSLCAP0001003154873.926967.5676
ENSG00000149658homo_sapiensENSP0000035936483.720977.2809lates_calcariferENSLCAP0001003007173.239467.6056
ENSG00000149658homo_sapiensENSP0000035936490.518883.1843xenopus_tropicalisENSXETP0000011588887.543380.4498
ENSG00000149658homo_sapiensENSP0000035936495.348889.6243chrysemys_picta_belliiENSCPBP0000003944195.348889.6243
ENSG00000149658homo_sapiensENSP0000035936486.225480.8587sphenodon_punctatusENSSPUP0000001964894.509888.6274
ENSG00000149658homo_sapiensENSP0000035936491.949984.0787crocodylus_porosusENSCPRP0000500808284.818577.5578
ENSG00000149658homo_sapiensENSP0000035936491.592186.0465laticauda_laticaudataENSLLTP0000001947091.103285.5872
ENSG00000149658homo_sapiensENSP0000035936492.844486.941notechis_scutatusENSNSUP0000000833891.696185.8657
ENSG00000149658homo_sapiensENSP0000035936491.413285.8676pseudonaja_textilisENSPTXP0000001911090.925385.4093
ENSG00000149658homo_sapiensENSP0000035936494.812289.2665anas_platyrhynchos_platyrhynchosENSAPLP0000002318978.63574.0356
ENSG00000149658homo_sapiensENSP0000035936495.706689.9821gallus_gallusENSGALP0001003584995.365489.6613
ENSG00000149658homo_sapiensENSP0000035936493.559987.8354meleagris_gallopavoENSMGAP0000003029894.746488.9493
ENSG00000149658homo_sapiensENSP0000035936487.119981.932serinus_canariaENSSCAP0000002051695.303389.6282
ENSG00000149658homo_sapiensENSP0000035936495.706689.9821parus_majorENSPMJP0000000910395.365489.6613
ENSG00000149658homo_sapiensENSP0000035936492.844487.1199anolis_carolinensisENSACAP0000000543292.678686.9643
ENSG00000149658homo_sapiensENSP0000035936483.005474.9553neolamprologus_brichardiENSNBRP0000001055176.821269.3709
ENSG00000149658homo_sapiensENSP0000035936483.184376.3864neolamprologus_brichardiENSNBRP0000001986977.629471.2855
ENSG00000149658homo_sapiensENSP0000035936492.844487.1199naja_najaENSNNAP0000000490791.696186.0424
ENSG00000149658homo_sapiensENSP0000035936493.559986.4043podarcis_muralisENSPMRP0000000567390.017283.1325
ENSG00000149658homo_sapiensENSP0000035936493.38187.4776geospiza_fortisENSGFOP0000001436094.565288.587
ENSG00000149658homo_sapiensENSP0000035936494.812288.9088taeniopygia_guttataENSTGUP0000003534393.309987.5
ENSG00000149658homo_sapiensENSP0000035936488.014378.8909erpetoichthys_calabaricusENSECRP0000001265086.01477.0979
ENSG00000149658homo_sapiensENSP0000035936481.753174.0608kryptolebias_marmoratusENSKMAP0000000742075.164568.0921
ENSG00000149658homo_sapiensENSP0000035936484.436577.6386kryptolebias_marmoratusENSKMAP0000002355676.87370.684
ENSG00000149658homo_sapiensENSP0000035936491.234385.5098salvator_merianaeENSSMRP0000001629992.391386.5942
ENSG00000149658homo_sapiensENSP0000035936481.037674.4186oryzias_javanicusENSOJAP0000000926173.898967.863
ENSG00000149658homo_sapiensENSP0000035936474.060866.5474oryzias_javanicusENSOJAP0000003487674.460466.9065
ENSG00000149658homo_sapiensENSP0000035936482.468776.0286amphilophus_citrinellusENSACIP0000002593481.592975.2212
ENSG00000149658homo_sapiensENSP0000035936480.32273.1664amphilophus_citrinellusENSACIP0000001449080.610473.4291
ENSG00000149658homo_sapiensENSP0000035936483.363276.0286dicentrarchus_labraxENSDLAP0000507845875.282768.6591
ENSG00000149658homo_sapiensENSP0000035936481.395374.9553dicentrarchus_labraxENSDLAP0000501897874.104268.241
ENSG00000149658homo_sapiensENSP0000035936483.899876.2075amphiprion_perculaENSAPEP0000003079075.767468.8207
ENSG00000149658homo_sapiensENSP0000035936485.330978.5331amphiprion_perculaENSAPEP0000001225877.309671.1507
ENSG00000149658homo_sapiensENSP0000035936484.078776.7442oryzias_sinensisENSOSIP0000001494476.797470.098
ENSG00000149658homo_sapiensENSP0000035936482.110973.703oryzias_sinensisENSOSIP0000003965375.369567.6519
ENSG00000149658homo_sapiensENSP0000035936493.917787.6565pelodiscus_sinensisENSPSIP0000000596493.582987.344
ENSG00000149658homo_sapiensENSP0000035936495.169989.4454gopherus_evgoodeiENSGEVP0000500898295.169989.4454
ENSG00000149658homo_sapiensENSP0000035936494.812288.9088chelonoidis_abingdoniiENSCABP0000000144594.982189.0681
ENSG00000149658homo_sapiensENSP0000035936485.152178.3542seriola_dumeriliENSSDUP0000002174875.078969.0852
ENSG00000149658homo_sapiensENSP0000035936483.720976.0286seriola_dumeriliENSSDUP0000000049375.605868.6591
ENSG00000149658homo_sapiensENSP0000035936481.037673.1664cottoperca_gobioENSCGOP0000004580971.003164.1066
ENSG00000149658homo_sapiensENSP0000035936482.647674.7764cottoperca_gobioENSCGOP0000000848473.684266.6667
ENSG00000149658homo_sapiensENSP0000035936481.216573.8819cottoperca_gobioENSCGOP0000004341673.344166.7205
ENSG00000149658homo_sapiensENSP0000035936495.706689.9821struthio_camelus_australisENSSCUP0000000369395.365489.6613
ENSG00000149658homo_sapiensENSP0000035936495.706689.9821anser_brachyrhynchusENSABRP0000000658695.365489.6613
ENSG00000149658homo_sapiensENSP0000035936483.005476.2075gasterosteus_aculeatusENSGACP0000000343376.441570.1812
ENSG00000149658homo_sapiensENSP0000035936483.363275.1342gasterosteus_aculeatusENSGACP0000001589277.024869.4215
ENSG00000149658homo_sapiensENSP0000035936481.395373.703cynoglossus_semilaevisENSCSEP0000003212282.427574.6377
ENSG00000149658homo_sapiensENSP0000035936482.647674.2397poecilia_formosaENSPFOP0000000534276.237668.4818
ENSG00000149658homo_sapiensENSP0000035936484.794377.6386poecilia_formosaENSPFOP0000000547876.823370.3404
ENSG00000149658homo_sapiensENSP0000035936481.753175.3131myripristis_murdjanENSMMDP0000504344775.288369.3575
ENSG00000149658homo_sapiensENSP0000035936486.225477.9964myripristis_murdjanENSMMDP0000500766077.367669.9839
ENSG00000149658homo_sapiensENSP0000035936483.184375.6708sander_luciopercaENSSLUP0000003523572.317365.7854
ENSG00000149658homo_sapiensENSP0000035936484.257677.8175sander_luciopercaENSSLUP0000001200473.250467.6516
ENSG00000149658homo_sapiensENSP0000035936495.527789.6243strigops_habroptilaENSSHBP0000501219095.187289.3048
ENSG00000149658homo_sapiensENSP0000035936485.330978.3542amphiprion_ocellarisENSAOCP0000002517077.309670.9887
ENSG00000149658homo_sapiensENSP0000035936483.899876.2075amphiprion_ocellarisENSAOCP0000003093775.767468.8207
ENSG00000149658homo_sapiensENSP0000035936495.348889.4454terrapene_carolina_triunguisENSTMTP0000000208695.348889.4454
ENSG00000149658homo_sapiensENSP0000035936485.330977.4597hucho_huchoENSHHUP0000005084678.84371.5703
ENSG00000149658homo_sapiensENSP0000035936484.257676.9231hucho_huchoENSHHUP0000001334676.710170.0326
ENSG00000149658homo_sapiensENSP0000035936480.858775.6708hucho_huchoENSHHUP0000003806576.222671.3322
ENSG00000149658homo_sapiensENSP0000035936483.54277.102hucho_huchoENSHHUP0000004065075.566369.7411
ENSG00000149658homo_sapiensENSP0000035936485.330977.6386betta_splendensENSBSLP0000001072577.059870.1131
ENSG00000149658homo_sapiensENSP0000035936481.753173.3453betta_splendensENSBSLP0000004586669.137762.0272
ENSG00000149658homo_sapiensENSP0000035936485.330977.9964pygocentrus_nattereriENSPNAP0000000643677.941271.2418
ENSG00000149658homo_sapiensENSP0000035936482.647675.6708anabas_testudineusENSATEP0000004391374.157367.8973
ENSG00000149658homo_sapiensENSP0000035936483.005474.9553anabas_testudineusENSATEP0000003469375.324768.0195
ENSG00000149658homo_sapiensENSP0000035936457.066244.5438ciona_savignyiENSCSAVP0000001869654.623342.637
ENSG00000149658homo_sapiensENSP0000035936427.370318.068saccharomyces_cerevisiaeYDR374C5033.0065
ENSG00000149658homo_sapiensENSP0000035936483.184375.6708seriola_lalandi_dorsalisENSSLDP000000325067568.2258
ENSG00000149658homo_sapiensENSP0000035936485.152178.3542seriola_lalandi_dorsalisENSSLDP0000000122775.796269.7452
ENSG00000149658homo_sapiensENSP0000035936483.720976.0286labrus_bergyltaENSLBEP0000001831276.221569.2182
ENSG00000149658homo_sapiensENSP0000035936484.794378.3542labrus_bergyltaENSLBEP0000001551376.948171.1039
ENSG00000149658homo_sapiensENSP0000035936484.615477.6386pundamilia_nyerereiENSPNYP0000000289376.785770.4545
ENSG00000149658homo_sapiensENSP0000035936483.363275.1342pundamilia_nyerereiENSPNYP0000001852374.799467.4157
ENSG00000149658homo_sapiensENSP0000035936482.468774.7764mastacembelus_armatusENSMAMP0000003615875.203968.1892
ENSG00000149658homo_sapiensENSP0000035936484.973277.9964mastacembelus_armatusENSMAMP0000001635276.860870.5502
ENSG00000149658homo_sapiensENSP0000035936483.899875.6708stegastes_partitusENSSPAP0000001987375.280967.8973
ENSG00000149658homo_sapiensENSP0000035936484.973277.9964stegastes_partitusENSSPAP0000000471776.860870.5502
ENSG00000149658homo_sapiensENSP0000035936484.794377.6386oncorhynchus_tshawytschaENSOTSP0000501223276.451670
ENSG00000149658homo_sapiensENSP0000035936485.509877.6386oncorhynchus_tshawytschaENSOTSP0000507421678.877971.6172
ENSG00000149658homo_sapiensENSP0000035936482.468774.2397oncorhynchus_tshawytschaENSOTSP0000501784368.195361.3905
ENSG00000149658homo_sapiensENSP0000035936469.051962.9696oncorhynchus_tshawytschaENSOTSP0000503483172.556466.1654
ENSG00000149658homo_sapiensENSP0000035936485.330978.5331acanthochromis_polyacanthusENSAPOP0000000863777.309671.1507
ENSG00000149658homo_sapiensENSP0000035936484.078776.3864acanthochromis_polyacanthusENSAPOP0000002288275.806468.871
ENSG00000149658homo_sapiensENSP0000035936495.706689.9821aquila_chrysaetos_chrysaetosENSACCP0002000260495.365489.6613
ENSG00000149658homo_sapiensENSP0000035936480.143172.8086nothobranchius_furzeriENSNFUP0001503208468.711762.4233
ENSG00000149658homo_sapiensENSP0000035936483.899876.7442nothobranchius_furzeriENSNFUP0001503263576.50969.9837
ENSG00000149658homo_sapiensENSP0000035936484.436577.4597cyprinodon_variegatusENSCVAP0000001200376.74870.4065
ENSG00000149658homo_sapiensENSP0000035936481.753173.5241cyprinodon_variegatusENSCVAP0000001517574.308966.8293
ENSG00000149658homo_sapiensENSP0000035936484.436576.5653denticeps_clupeoidesENSDCDP0000003266074.683567.7215
ENSG00000149658homo_sapiensENSP0000035936485.509877.8175denticeps_clupeoidesENSDCDP0000006214877.471670.5024
ENSG00000149658homo_sapiensENSP0000035936485.152178.1753larimichthys_croceaENSLCRP0000504045177.022770.712
ENSG00000149658homo_sapiensENSP0000035936483.363275.8497larimichthys_croceaENSLCRP0000506093066.005760.0567
ENSG00000149658homo_sapiensENSP0000035936482.826575.492takifugu_rubripesENSTRUP0000001016578.077671.1636
ENSG00000149658homo_sapiensENSP0000035936485.152176.3864takifugu_rubripesENSTRUP0000008197669.286862.1543
ENSG00000149658homo_sapiensENSP0000035936495.348889.4454ficedula_albicollisENSFALP0000001091595.348889.4454
ENSG00000149658homo_sapiensENSP0000035936483.720976.7442hippocampus_comesENSHCOP0000000895376.470670.098
ENSG00000149658homo_sapiensENSP0000035936483.005475.492hippocampus_comesENSHCOP0000000698677.59270.5686
ENSG00000149658homo_sapiensENSP0000035936485.330977.9964cyprinus_carpio_carpioENSCCRP0000017015078.068771.3584
ENSG00000149658homo_sapiensENSP0000035936484.794377.2809cyprinus_carpio_carpioENSCCRP000000259567568.3544
ENSG00000149658homo_sapiensENSP0000035936495.706689.9821coturnix_japonicaENSCJPP0000500282495.365489.6613
ENSG00000149658homo_sapiensENSP0000035936482.647674.2397poecilia_latipinnaENSPLAP0000000488576.237668.4818
ENSG00000149658homo_sapiensENSP0000035936483.184376.0286poecilia_latipinnaENSPLAP0000000455575.242768.7702
ENSG00000149658homo_sapiensENSP0000035936485.152177.8175sinocyclocheilus_grahamiENSSGRP0000001974777.777871.0784
ENSG00000149658homo_sapiensENSP0000035936485.330977.9964sinocyclocheilus_grahamiENSSGRP0000005817678.325171.5928
ENSG00000149658homo_sapiensENSP0000035936484.615477.6386maylandia_zebraENSMZEP0000503163076.785770.4545
ENSG00000149658homo_sapiensENSP0000035936483.720975.492maylandia_zebraENSMZEP0000503531876.973769.4079
ENSG00000149658homo_sapiensENSP0000035936480.500972.8086tetraodon_nigroviridisENSTNIP0000000658483.333375.3704
ENSG00000149658homo_sapiensENSP0000035936481.037673.1664tetraodon_nigroviridisENSTNIP0000001546083.272175.1838
ENSG00000149658homo_sapiensENSP0000035936479.248770.483paramormyrops_kingsleyaeENSPKIP0000002012878.966170.2317
ENSG00000149658homo_sapiensENSP0000035936481.216572.9875paramormyrops_kingsleyaeENSPKIP0000002076275.666768
ENSG00000149658homo_sapiensENSP0000035936483.54276.0286scleropages_formosusENSSFOP0001500033177.317970.3642
ENSG00000149658homo_sapiensENSP0000035936492.307784.0787leptobrachium_leishanenseENSLLEP0000002358488.965581.0345
ENSG00000149658homo_sapiensENSP0000035936483.720977.102scophthalmus_maximusENSSMAP0000001242871.232965.6012
ENSG00000149658homo_sapiensENSP0000035936483.005474.5975scophthalmus_maximusENSSMAP0000004122973.186165.7729
ENSG00000149658homo_sapiensENSP0000035936484.257676.9231oryzias_melastigmaENSOMEP0000001057077.086770.3764
ENSG00000149658homo_sapiensENSP0000035936482.110974.0608oryzias_melastigmaENSOMEP0000000201375.742668.3168

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000932located_in P-body1IDAHomo_sapiens(9606)Component
GO:0002376involved_in immune system process1IEAHomo_sapiens(9606)Process
GO:0002577involved_in regulation of antigen processing and presentation1ISSHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003729enables mRNA binding1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005737is_active_in cytoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0007612involved_in learning1ISSHomo_sapiens(9606)Process
GO:0007613involved_in memory1ISSHomo_sapiens(9606)Process
GO:0010494located_in cytoplasmic stress granule1IDAHomo_sapiens(9606)Component
GO:0034063involved_in stress granule assembly1IDAHomo_sapiens(9606)Process
GO:0043022enables ribosome binding1IDAHomo_sapiens(9606)Function
GO:0043488involved_in regulation of mRNA stability1IDAHomo_sapiens(9606)Process
GO:0045727involved_in positive regulation of translation1IMPHomo_sapiens(9606)Process
GO:0045948NOT involved_in positive regulation of translational initiation2IDAHomo_sapiens(9606)Process
GO:0061157involved_in mRNA destabilization2IBA,IDAHomo_sapiens(9606)Process
GO:0070925involved_in organelle assembly1IDAHomo_sapiens(9606)Process
GO:1900271involved_in regulation of long-term synaptic potentiation1ISSHomo_sapiens(9606)Process
GO:1902667involved_in regulation of axon guidance1ISSHomo_sapiens(9606)Process
GO:1990247enables N6-methyladenosine-containing RNA binding2IBA,IDAHomo_sapiens(9606)Function

Expression