Functions and Diseases

RBP Type Canonical_RBPs
Diseases Disease
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Metabolic enzyme
Localizations N.A.
BulkPerturb-seq

Description

Ensembl ID ENSG00000148384 Gene ID 56623 Accession 21474
Symbol INPP5E Alias Full Name
Status Confidence Length 11227 bases Strand Minus strand
Position 9 : 136428619 - 136439845 RNA binding domain Exo_endo_phos
Summary

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000360777 Exo_endo_phos PF03372 3.2e-11 1
ENSP00000501984 Exo_endo_phos PF03372 2.6e-09 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
INPP5E-206 ENST00000676019 3315 610aa ENSP00000501984
INPP5E-201 ENST00000371712 3417 644aa ENSP00000360777
INPP5E-204 ENST00000674693 261 No protein -
INPP5E-203 ENST00000674513 532 No protein -
INPP5E-205 ENST00000675256 264 88aa ENSP00000502517
INPP5E-202 ENST00000635815 4311 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000139located_in Golgi membrane1IEAHomo_sapiens(9606)Component
GO:0001726located_in ruffle1IEAHomo_sapiens(9606)Component
GO:0004439enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity2IBA,TASHomo_sapiens(9606)Function
GO:0004445enables inositol-polyphosphate 5-phosphatase activity1TASHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus2IBA,ISSHomo_sapiens(9606)Component
GO:0005794is_active_in Golgi apparatus1IBAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0005886located_in plasma membrane1IEAHomo_sapiens(9606)Component
GO:0005929located_in cilium1TASHomo_sapiens(9606)Component
GO:0005930is_active_in axoneme2IBA,IDAHomo_sapiens(9606)Component
GO:0006661involved_in phosphatidylinositol biosynthetic process1TASHomo_sapiens(9606)Process
GO:0008150involved_in biological_process1NDHomo_sapiens(9606)Process
GO:0014067involved_in negative regulation of phosphatidylinositol 3-kinase signaling1IEAHomo_sapiens(9606)Process
GO:0016314enables phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity1IEAHomo_sapiens(9606)Function
GO:0017148involved_in negative regulation of translation1IEAHomo_sapiens(9606)Process
GO:0032580located_in Golgi cisterna membrane1IEAHomo_sapiens(9606)Component
GO:0034485enables phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity1IEAHomo_sapiens(9606)Function
GO:0036092involved_in phosphatidylinositol-3-phosphate biosynthetic process1IEAHomo_sapiens(9606)Process
GO:0043813enables phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity1IEAHomo_sapiens(9606)Function
GO:0046856involved_in phosphatidylinositol dephosphorylation1IBAHomo_sapiens(9606)Process
GO:1903565involved_in negative regulation of protein localization to cilium1IEAHomo_sapiens(9606)Process

Expression