RBPWorld - a comprehensive database of RNA Binding Proteins

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Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	E3 ligase
Localizations	Nucleoli
BulkPerturb-seq

Description

Ensembl ID	ENSG00000146063	Gene ID	90933	Accession	19013
Symbol	TRIM41	Alias	RINCK	Full Name	tripartite motif containing 41
Status	Confidence	Length	13310 bases	Strand	Plus strand
Position	5 : 181222499 - 181235808	RNA binding domain	SPRY
Summary	This gene encodes a member of the tripartite motif (TRIM) family. The TRIM family is characterized by a signature motif composed of a RING finger, one or more B-box domains, and a coiled-coil region. This encoded protein may play a role in protein kinase C signaling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000320869	SPRY	PF00622	9.1e-12	1

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal
35562987	The Roles of Ubiquitination in Pathogenesis of Influenza Virus Infection.	Eun-Sook Park	2022-04-21	International journal of molecular sciences
34835115	How Influenza A Virus NS1 Deals with the Ubiquitin System to Evade Innate Immunity.	Laurie-Anne Lamotte	2021-11-19	Viruses

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
TRIM41-208	ENST00000515499	914	191aa	ENSP00000426803
TRIM41-201	ENST00000315073	3645	630aa	ENSP00000320869
TRIM41-204	ENST00000508930	3834	No protein	-
TRIM41-202	ENST00000351937	2696	518aa	ENSP00000336749
TRIM41-203	ENST00000503114	1904	362aa	ENSP00000424979
TRIM41-207	ENST00000515223	5707	No protein	-
TRIM41-209	ENST00000515834	7015	No protein	-
TRIM41-206	ENST00000514219	459	116aa	ENSP00000426790
TRIM41-205	ENST00000510072	752	No protein	-

Gene Model

Click here to download ENSG00000146063's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
36196	Platelet Function Tests	1.4800000E-006	-
36221	Platelet Function Tests	2.1200000E-007	-

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000146063's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005730	located_in nucleolus	1	IDA	Homo_sapiens(9606)	Component
GO:0005737	located_in cytoplasm	1	IEA	Homo_sapiens(9606)	Component
GO:0006513	involved_in protein monoubiquitination	1	IDA	Homo_sapiens(9606)	Process
GO:0008270	enables zinc ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0016567	involved_in protein ubiquitination	1	IBA	Homo_sapiens(9606)	Process
GO:0016604	is_active_in nuclear body	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0042802	enables identical protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0051607	involved_in defense response to virus	1	IDA	Homo_sapiens(9606)	Process
GO:0060340	involved_in positive regulation of type I interferon-mediated signaling pathway	1	IDA	Homo_sapiens(9606)	Process
GO:0061630	enables ubiquitin protein ligase activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0071222	involved_in cellular response to lipopolysaccharide	1	IMP	Homo_sapiens(9606)	Process
GO:0071225	involved_in cellular response to muramyl dipeptide	1	IMP	Homo_sapiens(9606)	Process

Expression