Ensembl ID ENSG00000144161 Gene ID
84524 Accession
30941
Symbol
ZC3H8
Alias
Fliz1;ZC3HDC8
Full Name
zinc finger CCCH-type containing 8
Status
Confidence
Length
43514 bases
Strand
Minus strand
Position
2 : 112211529 - 112255042
RNA binding domain
zf-CCCH , zf-CCCH_2
Summary
Enables RNA binding activity. Involved in several processes, including positive regulation of thymocyte apoptotic process; regulation of transcription, DNA-templated; and snRNA transcription. Located in Cajal body; histone locus body; and transcriptionally active chromatin. Part of transcription elongation factor complex. [provided by Alliance of Genome Resources, Apr 2022]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000386488
zf-CCCH
PF00642 3.2e-11
1
ENSP00000386488
zf-CCCH
PF00642 3.2e-11
2
ENSP00000386488
zf-CCCH_2
PF14608 3.3e-09
3
ENSP00000386488
zf-CCCH_2
PF14608 3.3e-09
4
ENSP00000386488
zf-CCCH_2
PF14608 3.3e-09
5
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
23932780 The little elongation complex functions at initiation and elongation phases of snRNA gene transcription.
Deqing Hu
2013-08-22
Molecular cell
29474390 Transcriptomes of Trypanosoma brucei rhodesiense from sleeping sickness patients, rodents and culture: Effects of strain, growth conditions and RNA preparation methods.
Julius Mulindwa
2018-02-01
PLoS neglected tropical diseases
Name
Transcript ID
bp
Protein
Translation ID
ZC3H8-201
ENST00000409573
5892
291aa
ENSP00000386488
ZC3H8-205
ENST00000476902
860
No protein
-
ZC3H8-204
ENST00000474234
847
No protein
-
ZC3H8-203
ENST00000466259
565
No protein
-
ZC3H8-202
ENST00000464305
554
No protein
-
ZC3H8-206
ENST00000495264
319
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000144161 homo_sapiens ENSP00000253048 11.3584 7.52111 homo_sapiens ENSP00000386488 50.8591 33.677 ENSG00000144161 homo_sapiens ENSP00000386764 16.148 12.5315 homo_sapiens ENSP00000386488 65.9794 51.2027
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000144161 homo_sapiens ENSP00000386488 98.6254 98.6254 nomascus_leucogenys ENSNLEP00000001922 97.619 97.619 ENSG00000144161 homo_sapiens ENSP00000386488 100 99.3127 pan_paniscus ENSPPAP00000009677 100 99.3127 ENSG00000144161 homo_sapiens ENSP00000386488 97.5945 96.2199 pongo_abelii ENSPPYP00000013563 94.0397 92.7152 ENSG00000144161 homo_sapiens ENSP00000386488 100 99.3127 pan_troglodytes ENSPTRP00000021176 100 99.3127 ENSG00000144161 homo_sapiens ENSP00000386488 99.6564 98.9691 gorilla_gorilla ENSGGOP00000008803 99.6564 98.9691 ENSG00000144161 homo_sapiens ENSP00000386488 70.1031 65.9794 choloepus_hoffmanni ENSCHOP00000009201 74.1818 69.8182 ENSG00000144161 homo_sapiens ENSP00000386488 83.5052 77.3196 erinaceus_europaeus ENSEEUP00000006352 81.5436 75.5034 ENSG00000144161 homo_sapiens ENSP00000386488 66.6667 60.1375 echinops_telfairi ENSETEP00000013437 65.5405 59.1216 ENSG00000144161 homo_sapiens ENSP00000386488 87.2852 84.8797 callithrix_jacchus ENSCJAP00000078371 86.1017 83.7288 ENSG00000144161 homo_sapiens ENSP00000386488 95.189 94.5017 cercocebus_atys ENSCATP00000014534 92.953 92.2819 ENSG00000144161 homo_sapiens ENSP00000386488 97.5945 96.9072 macaca_fascicularis ENSMFAP00000016722 96.2712 95.5932 ENSG00000144161 homo_sapiens ENSP00000386488 97.2509 96.9072 macaca_mulatta ENSMMUP00000041412 95.9322 95.5932 ENSG00000144161 homo_sapiens ENSP00000386488 97.5945 96.9072 macaca_nemestrina ENSMNEP00000021502 96.2712 95.5932 ENSG00000144161 homo_sapiens ENSP00000386488 97.2509 96.5636 papio_anubis ENSPANP00000009595 95.9322 95.2542 ENSG00000144161 homo_sapiens ENSP00000386488 96.9072 96.2199 mandrillus_leucophaeus ENSMLEP00000011615 95.5932 94.9153 ENSG00000144161 homo_sapiens ENSP00000386488 78.3505 74.9141 tursiops_truncatus ENSTTRP00000012480 74.026 70.7792 ENSG00000144161 homo_sapiens ENSP00000386488 91.0653 87.9725 vulpes_vulpes ENSVVUP00000040130 86.8852 83.9344 ENSG00000144161 homo_sapiens ENSP00000386488 87.2852 79.3814 mus_spretus MGP_SPRETEiJ_P0056626 83.2787 75.7377 ENSG00000144161 homo_sapiens ENSP00000386488 92.7835 89.6907 equus_asinus ENSEASP00005041984 88.2353 85.2941 ENSG00000144161 homo_sapiens ENSP00000386488 86.9416 80.4124 capra_hircus ENSCHIP00000009201 84.0532 77.7409 ENSG00000144161 homo_sapiens ENSP00000386488 87.9725 83.1615 loxodonta_africana ENSLAFP00000003902 84.4884 79.868 ENSG00000144161 homo_sapiens ENSP00000386488 93.1272 90.378 panthera_leo ENSPLOP00000000371 87.1383 84.5659 ENSG00000144161 homo_sapiens ENSP00000386488 88.3162 84.1924 ailuropoda_melanoleuca ENSAMEP00000026000 83.1715 79.288 ENSG00000144161 homo_sapiens ENSP00000386488 89.3471 81.4433 bos_indicus_hybrid ENSBIXP00005012989 85.8086 78.2178 ENSG00000144161 homo_sapiens ENSP00000386488 85.567 80.0687 oryctolagus_cuniculus ENSOCUP00000028419 70.1408 65.6338 ENSG00000144161 homo_sapiens ENSP00000386488 93.1272 90.0344 equus_caballus ENSECAP00000020190 88.5621 85.6209 ENSG00000144161 homo_sapiens ENSP00000386488 91.4089 87.9725 canis_lupus_familiaris ENSCAFP00845014428 80.8511 77.8116 ENSG00000144161 homo_sapiens ENSP00000386488 88.3162 85.9107 panthera_pardus ENSPPRP00000011936 83.7134 81.4332 ENSG00000144161 homo_sapiens ENSP00000386488 85.567 81.0997 marmota_marmota_marmota ENSMMMP00000002478 88.9286 84.2857 ENSG00000144161 homo_sapiens ENSP00000386488 84.8797 80.4124 balaenoptera_musculus ENSBMSP00010026145 86.6667 82.1053 ENSG00000144161 homo_sapiens ENSP00000386488 80.0687 71.8213 cavia_porcellus ENSCPOP00000007424 83.2143 74.6429 ENSG00000144161 homo_sapiens ENSP00000386488 93.1272 90.378 felis_catus ENSFCAP00000007496 87.1383 84.5659 ENSG00000144161 homo_sapiens ENSP00000386488 87.6289 83.5052 ursus_americanus ENSUAMP00000002656 83.0619 79.1531 ENSG00000144161 homo_sapiens ENSP00000386488 89.6907 81.7869 bison_bison_bison ENSBBBP00000001565 85.8553 78.2895 ENSG00000144161 homo_sapiens ENSP00000386488 89.6907 85.567 monodon_monoceros ENSMMNP00015027589 84.466 80.5825 ENSG00000144161 homo_sapiens ENSP00000386488 87.6289 82.4742 sus_scrofa ENSSSCP00000057275 82.5243 77.6699 ENSG00000144161 homo_sapiens ENSP00000386488 94.8454 92.0962 microcebus_murinus ENSMICP00000048845 90.1961 87.5817 ENSG00000144161 homo_sapiens ENSP00000386488 87.2852 77.3196 octodon_degus ENSODEP00000008825 83.0065 73.5294 ENSG00000144161 homo_sapiens ENSP00000386488 87.9725 79.0378 jaculus_jaculus ENSJJAP00000001725 83.9344 75.4098 ENSG00000144161 homo_sapiens ENSP00000386488 87.2852 81.4433 ovis_aries_rambouillet ENSOARP00020002484 80.6349 75.2381 ENSG00000144161 homo_sapiens ENSP00000386488 90.7216 86.5979 ursus_maritimus ENSUMAP00000011526 86.5574 82.6229 ENSG00000144161 homo_sapiens ENSP00000386488 77.3196 70.4467 ochotona_princeps ENSOPRP00000010207 80.9352 73.741 ENSG00000144161 homo_sapiens ENSP00000386488 85.9107 81.0997 delphinapterus_leucas ENSDLEP00000006409 78.8644 74.448 ENSG00000144161 homo_sapiens ENSP00000386488 58.7629 56.3574 physeter_catodon ENSPCTP00005011549 86.3636 82.8283 ENSG00000144161 homo_sapiens ENSP00000386488 87.2852 79.0378 mus_caroli MGP_CAROLIEiJ_P0054518 83.2787 75.4098 ENSG00000144161 homo_sapiens ENSP00000386488 87.9725 80.0687 mus_musculus ENSMUSP00000028866 83.9344 76.3934 ENSG00000144161 homo_sapiens ENSP00000386488 88.6598 80.756 dipodomys_ordii ENSDORP00000021355 84.8684 77.3026 ENSG00000144161 homo_sapiens ENSP00000386488 89.3471 85.9107 mustela_putorius_furo ENSMPUP00000009485 83.6013 80.3858 ENSG00000144161 homo_sapiens ENSP00000386488 81.4433 79.0378 aotus_nancymaae ENSANAP00000008214 80.6122 78.2313 ENSG00000144161 homo_sapiens ENSP00000386488 89.0034 86.5979 saimiri_boliviensis_boliviensis ENSSBOP00000023321 84.6405 82.3529 ENSG00000144161 homo_sapiens ENSP00000386488 90.378 86.9416 vicugna_pacos ENSVPAP00000005487 86.5132 83.2237 ENSG00000144161 homo_sapiens ENSP00000386488 83.5052 82.8179 chlorocebus_sabaeus ENSCSAP00000012854 95.2941 94.5098 ENSG00000144161 homo_sapiens ENSP00000386488 49.8282 48.11 tupaia_belangeri ENSTBEP00000013490 54.717 52.8302 ENSG00000144161 homo_sapiens ENSP00000386488 84.8797 77.6632 mesocricetus_auratus ENSMAUP00000012106 80.719 73.8562 ENSG00000144161 homo_sapiens ENSP00000386488 90.378 86.2543 phocoena_sinus ENSPSNP00000020938 78.0415 74.4807 ENSG00000144161 homo_sapiens ENSP00000386488 90.378 86.9416 camelus_dromedarius ENSCDRP00005013835 85.9477 82.6797 ENSG00000144161 homo_sapiens ENSP00000386488 93.1272 89.0034 carlito_syrichta ENSTSYP00000006110 89.1447 85.1974 ENSG00000144161 homo_sapiens ENSP00000386488 88.3162 85.9107 panthera_tigris_altaica ENSPTIP00000018660 83.7134 81.4332 ENSG00000144161 homo_sapiens ENSP00000386488 82.4742 75.945 rattus_norvegicus ENSRNOP00000023845 78.6885 72.459 ENSG00000144161 homo_sapiens ENSP00000386488 86.2543 81.7869 prolemur_simus ENSPSMP00000023451 78.1931 74.1433 ENSG00000144161 homo_sapiens ENSP00000386488 84.8797 77.3196 microtus_ochrogaster ENSMOCP00000016018 81.25 74.0132 ENSG00000144161 homo_sapiens ENSP00000386488 76.6323 69.0722 sorex_araneus ENSSARP00000011647 79.3594 71.5303 ENSG00000144161 homo_sapiens ENSP00000386488 85.9107 79.0378 peromyscus_maniculatus_bairdii ENSPEMP00000009921 82.7815 76.1589 ENSG00000144161 homo_sapiens ENSP00000386488 89.3471 81.7869 bos_mutus ENSBMUP00000032730 85.5263 78.2895 ENSG00000144161 homo_sapiens ENSP00000386488 80.756 72.5086 mus_spicilegus ENSMSIP00000021247 79.661 71.5254 ENSG00000144161 homo_sapiens ENSP00000386488 86.2543 78.6942 cricetulus_griseus_chok1gshd ENSCGRP00001018685 82.0261 74.8366 ENSG00000144161 homo_sapiens ENSP00000386488 67.354 64.2612 pteropus_vampyrus ENSPVAP00000003320 66.2162 63.1757 ENSG00000144161 homo_sapiens ENSP00000386488 78.0069 71.4777 myotis_lucifugus ENSMLUP00000004453 81.9495 75.0903 ENSG00000144161 homo_sapiens ENSP00000386488 86.2543 80.4124 rhinolophus_ferrumequinum ENSRFEP00010021811 77.2308 72 ENSG00000144161 homo_sapiens ENSP00000386488 83.5052 80.756 neovison_vison ENSNVIP00000021825 82.6531 79.932 ENSG00000144161 homo_sapiens ENSP00000386488 89.3471 81.4433 bos_taurus ENSBTAP00000021230 85.5263 77.9605 ENSG00000144161 homo_sapiens ENSP00000386488 89.6907 80.4124 heterocephalus_glaber_female ENSHGLP00000011673 85.2941 76.4706 ENSG00000144161 homo_sapiens ENSP00000386488 97.2509 96.5636 rhinopithecus_bieti ENSRBIP00000007040 95.9322 95.2542 ENSG00000144161 homo_sapiens ENSP00000386488 89.3471 85.9107 canis_lupus_dingo ENSCAFP00020022190 78.5499 75.5287 ENSG00000144161 homo_sapiens ENSP00000386488 92.7835 87.2852 sciurus_vulgaris ENSSVLP00005008667 88.5246 83.2787 ENSG00000144161 homo_sapiens ENSP00000386488 65.9794 59.7938 procavia_capensis ENSPCAP00000014399 63.5762 57.6159 ENSG00000144161 homo_sapiens ENSP00000386488 81.4433 73.5395 nannospalax_galili ENSNGAP00000007110 74.2947 67.0846 ENSG00000144161 homo_sapiens ENSP00000386488 89.0034 81.4433 bos_grunniens ENSBGRP00000042775 85.1974 77.9605 ENSG00000144161 homo_sapiens ENSP00000386488 89.3471 81.0997 chinchilla_lanigera ENSCLAP00000009888 85.2459 77.3771 ENSG00000144161 homo_sapiens ENSP00000386488 88.3162 79.3814 cervus_hanglu_yarkandensis ENSCHYP00000013623 82.9032 74.5161 ENSG00000144161 homo_sapiens ENSP00000386488 90.0344 81.0997 cervus_hanglu_yarkandensis ENSCHYP00000018897 86.1842 77.6316 ENSG00000144161 homo_sapiens ENSP00000386488 90.7216 86.5979 catagonus_wagneri ENSCWAP00000013879 85.1613 81.2903 ENSG00000144161 homo_sapiens ENSP00000386488 93.8144 88.6598 ictidomys_tridecemlineatus ENSSTOP00000005672 89.2157 84.3137 ENSG00000144161 homo_sapiens ENSP00000386488 90.7216 86.9416 otolemur_garnettii ENSOGAP00000002284 84.8875 81.3505 ENSG00000144161 homo_sapiens ENSP00000386488 90.378 89.3471 cebus_imitator ENSCCAP00000004527 89.4558 88.4354 ENSG00000144161 homo_sapiens ENSP00000386488 89.3471 88.3162 cebus_imitator ENSCCAP00000032510 92.1986 91.1348 ENSG00000144161 homo_sapiens ENSP00000386488 93.4708 88.3162 urocitellus_parryii ENSUPAP00010011915 88.8889 83.9869 ENSG00000144161 homo_sapiens ENSP00000386488 90.0344 81.7869 moschus_moschiferus ENSMMSP00000021429 86.1842 78.2895 ENSG00000144161 homo_sapiens ENSP00000386488 97.2509 96.9072 rhinopithecus_roxellana ENSRROP00000031531 95.9322 95.5932 ENSG00000144161 homo_sapiens ENSP00000386488 87.2852 79.0378 mus_pahari MGP_PahariEiJ_P0065496 83.2787 75.4098 ENSG00000144161 homo_sapiens ENSP00000386488 95.189 91.7526 propithecus_coquereli ENSPCOP00000019483 90.5229 87.2549 ENSG00000144161 homo_sapiens ENSP00000386488 32.9897 20.2749 caenorhabditis_elegans T26A8.4.2 16.7247 10.2787 ENSG00000144161 homo_sapiens ENSP00000386488 38.8316 24.055 ciona_intestinalis ENSCINP00000034981 11.566 7.16479 ENSG00000144161 homo_sapiens ENSP00000386488 36.7698 23.0241 hippocampus_comes ENSHCOP00000017324 12.2007 7.63968
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000122 involved_in negative regulation of transcription by RNA polymerase II 1 IEA Homo_sapiens(9606) Process GO:0000785 part_of chromatin 1 ISA Homo_sapiens(9606) Component GO:0000791 part_of euchromatin 1 IDA Homo_sapiens(9606) Component GO:0001162 enables RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding 1 IEA Homo_sapiens(9606) Function GO:0001227 enables DNA-binding transcription repressor activity, RNA polymerase II-specific 1 IEA Homo_sapiens(9606) Function GO:0003723 enables RNA binding 1 HDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005634 is_active_in nucleus 2 IBA,ISS Homo_sapiens(9606) Component GO:0005654 located_in nucleoplasm 2 IDA,TAS Homo_sapiens(9606) Component GO:0006915 involved_in apoptotic process 1 IEA Homo_sapiens(9606) Process GO:0008023 part_of transcription elongation factor complex 1 IDA Homo_sapiens(9606) Component GO:0015030 located_in Cajal body 1 IDA Homo_sapiens(9606) Component GO:0016604 located_in nuclear body 1 IDA Homo_sapiens(9606) Component GO:0033085 involved_in negative regulation of T cell differentiation in thymus 1 IMP Homo_sapiens(9606) Process GO:0035363 located_in histone locus body 1 IDA Homo_sapiens(9606) Component GO:0042795 involved_in snRNA transcription by RNA polymerase II 1 IMP Homo_sapiens(9606) Process GO:0042796 involved_in snRNA transcription by RNA polymerase III 1 IMP Homo_sapiens(9606) Process GO:0043029 involved_in T cell homeostasis 1 IMP Homo_sapiens(9606) Process GO:0045892 involved_in negative regulation of DNA-templated transcription 2 IDA,ISS Homo_sapiens(9606) Process GO:0045945 involved_in positive regulation of transcription by RNA polymerase III 1 IMP Homo_sapiens(9606) Process GO:0046677 involved_in response to antibiotic 1 IDA Homo_sapiens(9606) Process GO:0046872 enables metal ion binding 1 IEA Homo_sapiens(9606) Function GO:0070245 involved_in positive regulation of thymocyte apoptotic process 1 IMP Homo_sapiens(9606) Process
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