RBP Type
Canonical_RBPs
Diseases
CHIKV Flaviviruses HIV IAV RV SARS-COV-2 SINV Dengue Zika
Drug
N.A.
Main interacting RNAs
snRNA
Moonlighting functions
N.A.
Localizations
Stress granucle
BulkPerturb-seq
Ensembl ID ENSG00000144028 Gene ID
23020 Accession
30859
Symbol
SNRNP200
Alias
BRR2;RP33;HELIC2;ASCC3L1;U5-200KD
Full Name
small nuclear ribonucleoprotein U5 subunit 200
Status
Confidence
Length
46934 bases
Strand
Minus strand
Position
2 : 96274338 - 96321271
RNA binding domain
ResIII , DEAD
Summary
Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. [provided by RefSeq, Mar 2010]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000317123
DEAD
PF00270 1.9e-51
1
ENSP00000317123
DEAD
PF00270 1.9e-51
2
ENSP00000317123
ResIII
PF04851 3.1e-25
3
ENSP00000317123
ResIII
PF04851 3.1e-25
4
ENSP00000498933
DEAD
PF00270 2.4e-32
1
ENSP00000498933
DEAD
PF00270 2.4e-32
2
ENSP00000498933
ResIII
PF04851 1.3e-15
3
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
34196950 Emerging roles of spliceosome in cancer and immunity.
Hui Yang
2022-08-01
Protein & cell
36609432 IARA: a complete and curated atlas of the biogenesis of spliceosome machinery during RNA splicing.
S Kelren Rodrigues
2023-03-01
Life science alliance
34395430 Pre-mRNA Processing Factors and Retinitis Pigmentosa: RNA Splicing and Beyond.
Chunbo Yang
2021-01-01
Frontiers in cell and developmental biology
37333282 Large-scale map of RNA binding protein interactomes across the mRNA life-cycle.
Lena Street
2023-06-08
bioRxiv : the preprint server for biology
26593421 RNA mis-splicing in disease.
M Marina Scotti
2016-01-01
Nature reviews. Genetics
36321655 A forward genetic screen in C. elegans identifies conserved residues of spliceosomal proteins PRP8 and SNRNP200/BRR2 with a role in maintaining 5' splice site identity.
H Catiana Cartwright-Acar
2022-11-11
Nucleic acids research
35188580 The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Alexandra Bergfort
2022-03-21
Nucleic acids research
Name
Transcript ID
bp
Protein
Translation ID
SNRNP200-201
ENST00000323853
7194
2136aa
ENSP00000317123
SNRNP200-208
ENST00000497539
2666
No protein
-
SNRNP200-202
ENST00000429650
2637
No protein
-
SNRNP200-205
ENST00000480835
540
No protein
-
SNRNP200-206
ENST00000484372
581
No protein
-
SNRNP200-207
ENST00000493271
585
No protein
-
SNRNP200-203
ENST00000480242
3409
No protein
-
SNRNP200-204
ENST00000480615
1646
No protein
-
SNRNP200-209
ENST00000652267
4467
1375aa
ENSP00000498933
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
42095 Platelet Function Tests 2.0446500E-005 -
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000144028 homo_sapiens ENSP00000264233 22.0849 10.8494 homo_sapiens ENSP00000317123 26.779 13.1554 ENSG00000144028 homo_sapiens ENSP00000364543 27.2873 14.5265 homo_sapiens ENSP00000317123 15.9176 8.47378 ENSG00000144028 homo_sapiens ENSP00000507872 21.9226 10.3165 homo_sapiens ENSP00000317123 17.5094 8.2397 ENSG00000144028 homo_sapiens ENSP00000359454 41.7422 22.7875 homo_sapiens ENSP00000317123 28.0431 15.309 ENSG00000144028 homo_sapiens ENSP00000295488 31.1535 15.8038 homo_sapiens ENSP00000317123 16.0581 8.14607 ENSG00000144028 homo_sapiens ENSP00000377344 21.9626 10.514 homo_sapiens ENSP00000317123 17.603 8.42697 ENSG00000144028 homo_sapiens ENSP00000358159 57.9927 38.8738 homo_sapiens ENSP00000317123 59.7846 40.0749 ENSG00000144028 homo_sapiens ENSP00000230640 30.1344 13.7236 homo_sapiens ENSP00000317123 14.7004 6.69476
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000144028 homo_sapiens ENSP00000317123 96.5356 96.0206 nomascus_leucogenys ENSNLEP00000036752 98.1905 97.6667 ENSG00000144028 homo_sapiens ENSP00000317123 100 100 pan_paniscus ENSPPAP00000037836 100 100 ENSG00000144028 homo_sapiens ENSP00000317123 100 100 pongo_abelii ENSPPYP00000013456 100 100 ENSG00000144028 homo_sapiens ENSP00000317123 100 100 pan_troglodytes ENSPTRP00000020959 100 100 ENSG00000144028 homo_sapiens ENSP00000317123 25.0468 24.5318 gorilla_gorilla ENSGGOP00000048443 95.8781 93.9068 ENSG00000144028 homo_sapiens ENSP00000317123 100 100 gorilla_gorilla ENSGGOP00000005082 100 100 ENSG00000144028 homo_sapiens ENSP00000317123 99.485 98.4082 ornithorhynchus_anatinus ENSOANP00000047230 99.485 98.4082 ENSG00000144028 homo_sapiens ENSP00000317123 99.6723 98.97 sarcophilus_harrisii ENSSHAP00000000848 99.6723 98.97 ENSG00000144028 homo_sapiens ENSP00000317123 77.4345 76.8727 notamacropus_eugenii ENSMEUP00000009633 77.4707 76.9087 ENSG00000144028 homo_sapiens ENSP00000317123 58.1461 57.6311 choloepus_hoffmanni ENSCHOP00000011557 58.1189 57.6041 ENSG00000144028 homo_sapiens ENSP00000317123 98.8764 98.3614 dasypus_novemcinctus ENSDNOP00000008751 99.5287 99.0104 ENSG00000144028 homo_sapiens ENSP00000317123 86.7978 86.47 erinaceus_europaeus ENSEEUP00000011188 91.8731 91.5263 ENSG00000144028 homo_sapiens ENSP00000317123 73.1742 72.9869 echinops_telfairi ENSETEP00000000124 73.1742 72.9869 ENSG00000144028 homo_sapiens ENSP00000317123 15.2154 15.0749 callithrix_jacchus ENSCJAP00000058691 91.2921 90.4494 ENSG00000144028 homo_sapiens ENSP00000317123 100 99.9532 callithrix_jacchus ENSCJAP00000014168 100 99.9532 ENSG00000144028 homo_sapiens ENSP00000317123 100 100 cercocebus_atys ENSCATP00000004745 100 100 ENSG00000144028 homo_sapiens ENSP00000317123 100 99.9532 macaca_fascicularis ENSMFAP00000044258 100 99.9532 ENSG00000144028 homo_sapiens ENSP00000317123 100 99.9532 macaca_mulatta ENSMMUP00000030627 100 99.9532 ENSG00000144028 homo_sapiens ENSP00000317123 100 99.9064 macaca_nemestrina ENSMNEP00000018125 100 99.9064 ENSG00000144028 homo_sapiens ENSP00000317123 100 99.9532 papio_anubis ENSPANP00000010937 100 99.9532 ENSG00000144028 homo_sapiens ENSP00000317123 100 100 mandrillus_leucophaeus ENSMLEP00000004281 100 100 ENSG00000144028 homo_sapiens ENSP00000317123 99.6723 99.5318 tursiops_truncatus ENSTTRP00000004696 99.719 99.5785 ENSG00000144028 homo_sapiens ENSP00000317123 100 99.9064 vulpes_vulpes ENSVVUP00000037970 99.7665 99.673 ENSG00000144028 homo_sapiens ENSP00000317123 99.9064 99.6723 mus_spretus MGP_SPRETEiJ_P0056522 99.9064 99.6723 ENSG00000144028 homo_sapiens ENSP00000317123 99.9532 99.8596 equus_asinus ENSEASP00005003005 99.9532 99.8596 ENSG00000144028 homo_sapiens ENSP00000317123 99.8127 99.3446 capra_hircus ENSCHIP00000022847 99.3476 98.8816 ENSG00000144028 homo_sapiens ENSP00000317123 99.9064 99.485 loxodonta_africana ENSLAFP00000013115 99.9064 99.485 ENSG00000144028 homo_sapiens ENSP00000317123 100 99.9064 panthera_leo ENSPLOP00000028954 100 99.9064 ENSG00000144028 homo_sapiens ENSP00000317123 100 99.8596 ailuropoda_melanoleuca ENSAMEP00000009501 100 99.8596 ENSG00000144028 homo_sapiens ENSP00000317123 99.9064 99.2978 bos_indicus_hybrid ENSBIXP00005011152 99.9064 99.2978 ENSG00000144028 homo_sapiens ENSP00000317123 99.9532 99.8127 oryctolagus_cuniculus ENSOCUP00000008503 100 99.8595 ENSG00000144028 homo_sapiens ENSP00000317123 99.9532 99.8596 equus_caballus ENSECAP00000017686 99.9532 99.8596 ENSG00000144028 homo_sapiens ENSP00000317123 100 99.9064 canis_lupus_familiaris ENSCAFP00845008290 100 99.9064 ENSG00000144028 homo_sapiens ENSP00000317123 100 99.9064 panthera_pardus ENSPPRP00000010201 100 99.9064 ENSG00000144028 homo_sapiens ENSP00000317123 99.9064 99.8127 marmota_marmota_marmota ENSMMMP00000000865 99.9532 99.8595 ENSG00000144028 homo_sapiens ENSP00000317123 99.9064 99.7191 balaenoptera_musculus ENSBMSP00010023056 99.9064 99.7191 ENSG00000144028 homo_sapiens ENSP00000317123 99.9064 99.7191 cavia_porcellus ENSCPOP00000006107 99.9064 99.7191 ENSG00000144028 homo_sapiens ENSP00000317123 100 99.9064 felis_catus ENSFCAP00000032289 100 99.9064 ENSG00000144028 homo_sapiens ENSP00000317123 15.4026 15.3558 ursus_americanus ENSUAMP00000010166 100 99.696 ENSG00000144028 homo_sapiens ENSP00000317123 46.9101 46.0674 ursus_americanus ENSUAMP00000010169 95.8852 94.1627 ENSG00000144028 homo_sapiens ENSP00000317123 99.6723 98.97 monodelphis_domestica ENSMODP00000010540 99.6723 98.97 ENSG00000144028 homo_sapiens ENSP00000317123 99.9064 99.485 bison_bison_bison ENSBBBP00000028139 99.9064 99.485 ENSG00000144028 homo_sapiens ENSP00000317123 99.9064 99.7659 monodon_monoceros ENSMMNP00015024914 99.9064 99.7659 ENSG00000144028 homo_sapiens ENSP00000317123 99.8596 99.7191 sus_scrofa ENSSSCP00000008677 99.8596 99.7191 ENSG00000144028 homo_sapiens ENSP00000317123 99.9532 99.8596 microcebus_murinus ENSMICP00000004327 99.9532 99.8596 ENSG00000144028 homo_sapiens ENSP00000317123 99.8596 99.5787 octodon_degus ENSODEP00000011247 99.8596 99.5787 ENSG00000144028 homo_sapiens ENSP00000317123 99.9064 99.6723 jaculus_jaculus ENSJJAP00000024118 99.9064 99.6723 ENSG00000144028 homo_sapiens ENSP00000317123 99.9532 99.485 ovis_aries_rambouillet ENSOARP00020000313 99.9532 99.485 ENSG00000144028 homo_sapiens ENSP00000317123 100 99.9064 ursus_maritimus ENSUMAP00000017729 100 99.9064 ENSG00000144028 homo_sapiens ENSP00000317123 96.1142 95.9738 ochotona_princeps ENSOPRP00000014157 96.2043 96.0637 ENSG00000144028 homo_sapiens ENSP00000317123 99.8596 99.6723 delphinapterus_leucas ENSDLEP00000004404 99.4406 99.2541 ENSG00000144028 homo_sapiens ENSP00000317123 27.809 27.7622 physeter_catodon ENSPCTP00005022900 99.8319 99.6639 ENSG00000144028 homo_sapiens ENSP00000317123 56.9288 56.0861 physeter_catodon ENSPCTP00005010810 86.4865 85.2063 ENSG00000144028 homo_sapiens ENSP00000317123 99.8596 99.6255 mus_caroli MGP_CAROLIEiJ_P0054416 99.8596 99.6255 ENSG00000144028 homo_sapiens ENSP00000317123 99.9064 99.6723 mus_musculus ENSMUSP00000099509 99.9064 99.6723 ENSG00000144028 homo_sapiens ENSP00000317123 97.6124 97.191 dipodomys_ordii ENSDORP00000005492 98.8152 98.3886 ENSG00000144028 homo_sapiens ENSP00000317123 100 99.8127 mustela_putorius_furo ENSMPUP00000008879 100 99.8127 ENSG00000144028 homo_sapiens ENSP00000317123 97.2378 97.191 aotus_nancymaae ENSANAP00000038670 99.6163 99.5683 ENSG00000144028 homo_sapiens ENSP00000317123 12.4532 11.9382 aotus_nancymaae ENSANAP00000012246 92.3611 88.5417 ENSG00000144028 homo_sapiens ENSP00000317123 22.706 20.927 saimiri_boliviensis_boliviensis ENSSBOP00000012928 90.824 83.7079 ENSG00000144028 homo_sapiens ENSP00000317123 100 99.9532 saimiri_boliviensis_boliviensis ENSSBOP00000038855 100 99.9532 ENSG00000144028 homo_sapiens ENSP00000317123 61.6105 61.1423 vicugna_pacos ENSVPAP00000005975 61.9003 61.4299 ENSG00000144028 homo_sapiens ENSP00000317123 100 99.9532 chlorocebus_sabaeus ENSCSAP00000013404 100 99.9532 ENSG00000144028 homo_sapiens ENSP00000317123 59.176 58.9888 tupaia_belangeri ENSTBEP00000002968 60.1905 60 ENSG00000144028 homo_sapiens ENSP00000317123 99.9532 99.8127 mesocricetus_auratus ENSMAUP00000011158 99.9532 99.8127 ENSG00000144028 homo_sapiens ENSP00000317123 99.9064 99.8127 phocoena_sinus ENSPSNP00000006649 99.4408 99.3476 ENSG00000144028 homo_sapiens ENSP00000317123 99.9532 99.9064 camelus_dromedarius ENSCDRP00005028950 100 99.9532 ENSG00000144028 homo_sapiens ENSP00000317123 99.4382 99.3446 carlito_syrichta ENSTSYP00000009605 99.2987 99.2052 ENSG00000144028 homo_sapiens ENSP00000317123 99.5318 99.4382 panthera_tigris_altaica ENSPTIP00000003790 100 99.9059 ENSG00000144028 homo_sapiens ENSP00000317123 99.9532 99.8127 rattus_norvegicus ENSRNOP00000048598 99.813 99.6727 ENSG00000144028 homo_sapiens ENSP00000317123 99.9532 99.9064 prolemur_simus ENSPSMP00000025202 99.9532 99.9064 ENSG00000144028 homo_sapiens ENSP00000317123 97.4251 97.2378 microtus_ochrogaster ENSMOCP00000011585 99.5218 99.3305 ENSG00000144028 homo_sapiens ENSP00000317123 89.0918 88.5768 sorex_araneus ENSSARP00000009769 92.5584 92.0233 ENSG00000144028 homo_sapiens ENSP00000317123 32.1629 32.0693 peromyscus_maniculatus_bairdii ENSPEMP00000023753 99.8547 99.564 ENSG00000144028 homo_sapiens ENSP00000317123 99.9532 99.5318 bos_mutus ENSBMUP00000033480 99.9532 99.5318 ENSG00000144028 homo_sapiens ENSP00000317123 99.9064 99.6723 mus_spicilegus ENSMSIP00000023047 99.9064 99.6723 ENSG00000144028 homo_sapiens ENSP00000317123 99.8127 99.5787 cricetulus_griseus_chok1gshd ENSCGRP00001024862 99.766 99.5321 ENSG00000144028 homo_sapiens ENSP00000317123 88.9513 88.2022 pteropus_vampyrus ENSPVAP00000005544 90.5193 89.757 ENSG00000144028 homo_sapiens ENSP00000317123 97.9401 95.5524 myotis_lucifugus ENSMLUP00000018426 97.9401 95.5524 ENSG00000144028 homo_sapiens ENSP00000317123 99.8596 99.3914 myotis_lucifugus ENSMLUP00000009617 99.7195 99.252 ENSG00000144028 homo_sapiens ENSP00000317123 99.6723 98.97 vombatus_ursinus ENSVURP00010020187 99.6723 98.97 ENSG00000144028 homo_sapiens ENSP00000317123 99.9064 99.2509 rhinolophus_ferrumequinum ENSRFEP00010027419 99.9064 99.2509 ENSG00000144028 homo_sapiens ENSP00000317123 97.2378 97.0974 neovison_vison ENSNVIP00000019491 100 99.8556 ENSG00000144028 homo_sapiens ENSP00000317123 99.9064 99.2978 bos_taurus ENSBTAP00000001130 99.9064 99.2978 ENSG00000144028 homo_sapiens ENSP00000317123 99.9532 99.7191 heterocephalus_glaber_female ENSHGLP00000009273 99.9532 99.7191 ENSG00000144028 homo_sapiens ENSP00000317123 99.8596 99.8127 rhinopithecus_bieti ENSRBIP00000042961 99.3942 99.3476 ENSG00000144028 homo_sapiens ENSP00000317123 99.7659 99.4382 canis_lupus_dingo ENSCAFP00020027148 99.44 99.1134 ENSG00000144028 homo_sapiens ENSP00000317123 99.9532 99.9064 sciurus_vulgaris ENSSVLP00005012715 99.9532 99.9064 ENSG00000144028 homo_sapiens ENSP00000317123 99.6723 98.97 phascolarctos_cinereus ENSPCIP00000031009 99.6723 98.97 ENSG00000144028 homo_sapiens ENSP00000317123 82.3502 82.0693 procavia_capensis ENSPCAP00000008123 82.9326 82.6497 ENSG00000144028 homo_sapiens ENSP00000317123 100 99.9064 nannospalax_galili ENSNGAP00000023450 100 99.9064 ENSG00000144028 homo_sapiens ENSP00000317123 99.8596 99.4382 bos_grunniens ENSBGRP00000042850 99.9531 99.5314 ENSG00000144028 homo_sapiens ENSP00000317123 99.9064 99.5787 chinchilla_lanigera ENSCLAP00000005806 99.9064 99.5787 ENSG00000144028 homo_sapiens ENSP00000317123 100 99.7191 cervus_hanglu_yarkandensis ENSCHYP00000018204 100 99.7191 ENSG00000144028 homo_sapiens ENSP00000317123 100 99.7191 cervus_hanglu_yarkandensis ENSCHYP00000010623 100 99.7191 ENSG00000144028 homo_sapiens ENSP00000317123 99.8596 99.5787 catagonus_wagneri ENSCWAP00000008419 99.8596 99.5787 ENSG00000144028 homo_sapiens ENSP00000317123 99.9532 99.8596 ictidomys_tridecemlineatus ENSSTOP00000014650 99.9532 99.8596 ENSG00000144028 homo_sapiens ENSP00000317123 99.9532 99.9064 otolemur_garnettii ENSOGAP00000006162 99.9532 99.9064 ENSG00000144028 homo_sapiens ENSP00000317123 100 99.9532 cebus_imitator ENSCCAP00000032041 100 99.9532 ENSG00000144028 homo_sapiens ENSP00000317123 24.3446 23.0337 cebus_imitator ENSCCAP00000032149 91.5493 86.6197 ENSG00000144028 homo_sapiens ENSP00000317123 99.9064 99.8127 urocitellus_parryii ENSUPAP00010021561 99.9532 99.8595 ENSG00000144028 homo_sapiens ENSP00000317123 99.9532 99.5318 moschus_moschiferus ENSMMSP00000005219 99.9532 99.5318 ENSG00000144028 homo_sapiens ENSP00000317123 99.8596 99.8127 rhinopithecus_roxellana ENSRROP00000028467 99.3942 99.3476 ENSG00000144028 homo_sapiens ENSP00000317123 99.9064 99.7191 mus_pahari MGP_PahariEiJ_P0065397 99.9064 99.7191 ENSG00000144028 homo_sapiens ENSP00000317123 99.9532 99.9064 propithecus_coquereli ENSPCOP00000024807 99.9532 99.9064 ENSG00000144028 homo_sapiens ENSP00000317123 87.5468 74.8127 drosophila_melanogaster FBpp0075282 87.3016 74.6032 ENSG00000144028 homo_sapiens ENSP00000317123 89.0449 76.9195 ciona_intestinalis ENSCINP00000010465 88.8785 76.7757 ENSG00000144028 homo_sapiens ENSP00000317123 15.8708 14.3727 petromyzon_marinus ENSPMAP00000005246 92.8767 84.1096 ENSG00000144028 homo_sapiens ENSP00000317123 12.5468 10.9082 eptatretus_burgeri ENSEBUP00000025187 89.0365 77.4086 ENSG00000144028 homo_sapiens ENSP00000317123 50 43.1648 eptatretus_burgeri ENSEBUP00000026846 91.2041 78.7361 ENSG00000144028 homo_sapiens ENSP00000317123 25.0936 22.4251 eptatretus_burgeri ENSEBUP00000023197 89.4825 79.9666 ENSG00000144028 homo_sapiens ENSP00000317123 96.3015 90.9176 callorhinchus_milii ENSCMIP00000022410 96.1664 90.7901 ENSG00000144028 homo_sapiens ENSP00000317123 81.1798 77.809 latimeria_chalumnae ENSLACP00000000252 98.2993 94.2177 ENSG00000144028 homo_sapiens ENSP00000317123 97.0974 92.1816 lepisosteus_oculatus ENSLOCP00000018708 97.0065 92.0954 ENSG00000144028 homo_sapiens ENSP00000317123 96.161 89.6067 clupea_harengus ENSCHAP00000008393 96.0711 89.5229 ENSG00000144028 homo_sapiens ENSP00000317123 96.2079 90.3558 danio_rerio ENSDARP00000098660 96.298 90.4405 ENSG00000144028 homo_sapiens ENSP00000317123 96.1142 90.4494 carassius_auratus ENSCARP00000053348 95.845 90.1961 ENSG00000144028 homo_sapiens ENSP00000317123 96.3483 90.4963 astyanax_mexicanus ENSAMXP00000005892 96.3934 90.5386 ENSG00000144028 homo_sapiens ENSP00000317123 16.1517 14.0918 ictalurus_punctatus ENSIPUP00000011416 90.3141 78.7958 ENSG00000144028 homo_sapiens ENSP00000317123 26.2172 25 ictalurus_punctatus ENSIPUP00000030099 93.8023 89.4472 ENSG00000144028 homo_sapiens ENSP00000317123 8.19288 7.53745 ictalurus_punctatus ENSIPUP00000037240 96.6851 88.9503 ENSG00000144028 homo_sapiens ENSP00000317123 96.9101 90.7303 esox_lucius ENSELUP00000019584 96.8648 90.6879 ENSG00000144028 homo_sapiens ENSP00000317123 95.6929 89.9813 electrophorus_electricus ENSEEEP00000041123 96.3242 90.5749 ENSG00000144028 homo_sapiens ENSP00000317123 96.7697 90.4026 oncorhynchus_kisutch ENSOKIP00005038657 96.7244 90.3603 ENSG00000144028 homo_sapiens ENSP00000317123 94.8502 88.6704 oncorhynchus_kisutch ENSOKIP00005010563 94.6287 88.4633 ENSG00000144028 homo_sapiens ENSP00000317123 96.7697 90.5431 oncorhynchus_mykiss ENSOMYP00000077868 96.7244 90.5007 ENSG00000144028 homo_sapiens ENSP00000317123 96.8165 90.4963 oncorhynchus_mykiss ENSOMYP00000039457 96.7712 90.4539 ENSG00000144028 homo_sapiens ENSP00000317123 96.8633 90.4026 salmo_salar ENSSSAP00000144886 96.818 90.3603 ENSG00000144028 homo_sapiens ENSP00000317123 96.7228 90.4026 salmo_salar ENSSSAP00000118816 96.317 90.0233 ENSG00000144028 homo_sapiens ENSP00000317123 96.5356 90.2622 salmo_trutta ENSSTUP00000062301 96.7167 90.4315 ENSG00000144028 homo_sapiens ENSP00000317123 96.8633 90.4494 salmo_trutta ENSSTUP00000010815 96.818 90.4071 ENSG00000144028 homo_sapiens ENSP00000317123 96.5356 90.5899 gadus_morhua ENSGMOP00000005227 96.5808 90.6323 ENSG00000144028 homo_sapiens ENSP00000317123 93.867 87.7809 fundulus_heteroclitus ENSFHEP00000002898 96.2092 89.9712 ENSG00000144028 homo_sapiens ENSP00000317123 96.3951 90.4494 poecilia_reticulata ENSPREP00000013242 96.3951 90.4494 ENSG00000144028 homo_sapiens ENSP00000317123 85.1592 79.6816 xiphophorus_maculatus ENSXMAP00000002083 95.5859 89.4377 ENSG00000144028 homo_sapiens ENSP00000317123 96.4888 90.2154 oryzias_latipes ENSORLP00000015378 96.5792 90.2999 ENSG00000144028 homo_sapiens ENSP00000317123 96.4419 90.4026 cyclopterus_lumpus ENSCLMP00005011046 96.4419 90.4026 ENSG00000144028 homo_sapiens ENSP00000317123 96.3015 90.4026 oreochromis_niloticus ENSONIP00000013470 96.3015 90.4026 ENSG00000144028 homo_sapiens ENSP00000317123 82.4906 77.294 haplochromis_burtoni ENSHBUP00000027808 95.1404 89.1469 ENSG00000144028 homo_sapiens ENSP00000317123 96.3951 90.4026 astatotilapia_calliptera ENSACLP00000016508 96.3951 90.4026 ENSG00000144028 homo_sapiens ENSP00000317123 96.4888 90.6367 sparus_aurata ENSSAUP00010053873 96.4888 90.6367 ENSG00000144028 homo_sapiens ENSP00000317123 96.5356 90.8708 lates_calcarifer ENSLCAP00010056862 96.5356 90.8708 ENSG00000144028 homo_sapiens ENSP00000317123 97.7996 94.2416 xenopus_tropicalis ENSXETP00000002684 98.2134 94.6403 ENSG00000144028 homo_sapiens ENSP00000317123 99.4382 97.8933 chrysemys_picta_bellii ENSCPBP00000033023 99.2987 97.756 ENSG00000144028 homo_sapiens ENSP00000317123 13.1086 12.3127 sphenodon_punctatus ENSSPUP00000024531 97.561 91.6376 ENSG00000144028 homo_sapiens ENSP00000317123 99.1573 97.5187 sphenodon_punctatus ENSSPUP00000004885 99.1573 97.5187 ENSG00000144028 homo_sapiens ENSP00000317123 98.8296 97.3315 crocodylus_porosus ENSCPRP00005019332 99.2011 97.6974 ENSG00000144028 homo_sapiens ENSP00000317123 17.8839 17.2753 laticauda_laticaudata ENSLLTP00000006298 94.5545 91.3366 ENSG00000144028 homo_sapiens ENSP00000317123 81.0861 78.9326 laticauda_laticaudata ENSLLTP00000007858 99.028 96.3979 ENSG00000144028 homo_sapiens ENSP00000317123 95.1779 92.3221 notechis_scutatus ENSNSUP00000017135 97.3193 94.3992 ENSG00000144028 homo_sapiens ENSP00000317123 98.221 95.5524 pseudonaja_textilis ENSPTXP00000020239 97.355 94.71 ENSG00000144028 homo_sapiens ENSP00000317123 97.0974 95.3184 anas_platyrhynchos_platyrhynchos ENSAPLP00000004009 99.4724 97.6499 ENSG00000144028 homo_sapiens ENSP00000317123 97.706 95.7397 gallus_gallus ENSGALP00010028732 98.9568 96.9654 ENSG00000144028 homo_sapiens ENSP00000317123 27.5749 26.4981 meleagris_gallopavo ENSMGAP00000001419 98.9916 95.1261 ENSG00000144028 homo_sapiens ENSP00000317123 29.7285 27.2004 meleagris_gallopavo ENSMGAP00000017686 75.0591 68.6761 ENSG00000144028 homo_sapiens ENSP00000317123 97.3315 94.8034 serinus_canaria ENSSCAP00000021252 98.7179 96.1538 ENSG00000144028 homo_sapiens ENSP00000317123 24.8127 24.0169 parus_major ENSPMJP00000017931 92.0139 89.0625 ENSG00000144028 homo_sapiens ENSP00000317123 80.8052 78.7921 anolis_carolinensis ENSACAP00000000445 98.1239 95.6794 ENSG00000144028 homo_sapiens ENSP00000317123 78.8858 73.97 neolamprologus_brichardi ENSNBRP00000023523 95.9567 89.9772 ENSG00000144028 homo_sapiens ENSP00000317123 97.706 95.1779 naja_naja ENSNNAP00000005598 97.5234 95 ENSG00000144028 homo_sapiens ENSP00000317123 13.9513 13.4831 naja_naja ENSNNAP00000015815 94.3038 91.1392 ENSG00000144028 homo_sapiens ENSP00000317123 99.4382 97.5655 podarcis_muralis ENSPMRP00000014208 99.4382 97.5655 ENSG00000144028 homo_sapiens ENSP00000317123 97.4251 95.1311 geospiza_fortis ENSGFOP00000017844 97.5164 95.2202 ENSG00000144028 homo_sapiens ENSP00000317123 99.0169 96.5356 taeniopygia_guttata ENSTGUP00000031011 99.0169 96.5356 ENSG00000144028 homo_sapiens ENSP00000317123 98.736 96.3015 taeniopygia_guttata ENSTGUP00000027263 99.0141 96.5728 ENSG00000144028 homo_sapiens ENSP00000317123 96.8633 91.4326 erpetoichthys_calabaricus ENSECRP00000010180 95.5217 90.1662 ENSG00000144028 homo_sapiens ENSP00000317123 93.9607 87.8277 kryptolebias_marmoratus ENSKMAP00000004978 95.9828 89.7178 ENSG00000144028 homo_sapiens ENSP00000317123 99.1573 97.1442 salvator_merianae ENSSMRP00000019624 99.1573 97.1442 ENSG00000144028 homo_sapiens ENSP00000317123 84.8783 79.4944 amphilophus_citrinellus ENSACIP00000002273 95.2706 89.2275 ENSG00000144028 homo_sapiens ENSP00000317123 96.2547 90.4026 dicentrarchus_labrax ENSDLAP00005016536 96.2096 90.3603 ENSG00000144028 homo_sapiens ENSP00000317123 83.8951 78.7453 amphiprion_percula ENSAPEP00000017644 96.3441 90.4301 ENSG00000144028 homo_sapiens ENSP00000317123 96.4419 90.2154 oryzias_sinensis ENSOSIP00000034507 95.3704 89.213 ENSG00000144028 homo_sapiens ENSP00000317123 98.6891 96.7697 pelodiscus_sinensis ENSPSIP00000009777 98.7354 96.815 ENSG00000144028 homo_sapiens ENSP00000317123 97.9401 96.2079 gopherus_evgoodei ENSGEVP00005003077 97.0315 95.3154 ENSG00000144028 homo_sapiens ENSP00000317123 99.485 97.9401 chelonoidis_abingdonii ENSCABP00000028093 99.485 97.9401 ENSG00000144028 homo_sapiens ENSP00000317123 96.5356 90.6367 seriola_dumerili ENSSDUP00000029726 96.5356 90.6367 ENSG00000144028 homo_sapiens ENSP00000317123 95.9738 90.1217 cottoperca_gobio ENSCGOP00000038205 96.4252 90.5456 ENSG00000144028 homo_sapiens ENSP00000317123 98.4551 96.5824 struthio_camelus_australis ENSSCUP00000021283 99.4326 97.5414 ENSG00000144028 homo_sapiens ENSP00000317123 97.0974 95.3184 anser_brachyrhynchus ENSABRP00000012658 99.4724 97.6499 ENSG00000144028 homo_sapiens ENSP00000317123 96.4419 90.3558 gasterosteus_aculeatus ENSGACP00000015197 95.9478 89.8929 ENSG00000144028 homo_sapiens ENSP00000317123 95.927 89.8876 cynoglossus_semilaevis ENSCSEP00000025762 96.0619 90.0141 ENSG00000144028 homo_sapiens ENSP00000317123 6.88202 6.46067 cynoglossus_semilaevis ENSCSEP00000018856 83.5227 78.4091 ENSG00000144028 homo_sapiens ENSP00000317123 96.3483 90.4026 poecilia_formosa ENSPFOP00000015280 96.3032 90.3603 ENSG00000144028 homo_sapiens ENSP00000317123 96.161 90.0749 myripristis_murdjan ENSMMDP00005017580 96.0711 89.9906 ENSG00000144028 homo_sapiens ENSP00000317123 93.9139 87.9213 sander_lucioperca ENSSLUP00000032140 96.0728 89.9425 ENSG00000144028 homo_sapiens ENSP00000317123 99.3914 97.4251 strigops_habroptila ENSSHBP00005015968 99.3914 97.4251 ENSG00000144028 homo_sapiens ENSP00000317123 96.4888 90.6835 amphiprion_ocellaris ENSAOCP00000032305 96.4888 90.6835 ENSG00000144028 homo_sapiens ENSP00000317123 99.0169 97.0506 terrapene_carolina_triunguis ENSTMTP00000003461 98.9242 96.9598 ENSG00000144028 homo_sapiens ENSP00000317123 99.0169 97.0506 terrapene_carolina_triunguis ENSTMTP00000003406 98.9242 96.9598 ENSG00000144028 homo_sapiens ENSP00000317123 95.412 88.8109 hucho_hucho ENSHHUP00000030006 95.4567 88.8525 ENSG00000144028 homo_sapiens ENSP00000317123 96.8165 90.5899 hucho_hucho ENSHHUP00000032873 96.5904 90.3783 ENSG00000144028 homo_sapiens ENSP00000317123 96.4888 90.4494 betta_splendens ENSBSLP00000053639 96.4888 90.4494 ENSG00000144028 homo_sapiens ENSP00000317123 92.1816 86.0955 pygocentrus_nattereri ENSPNAP00000004468 95.2128 88.9265 ENSG00000144028 homo_sapiens ENSP00000317123 96.4888 90.5431 anabas_testudineus ENSATEP00000032751 96.4888 90.5431 ENSG00000144028 homo_sapiens ENSP00000317123 96.5356 90.5899 seriola_lalandi_dorsalis ENSSLDP00000013743 96.5356 90.5899 ENSG00000144028 homo_sapiens ENSP00000317123 96.2079 90.2622 labrus_bergylta ENSLBEP00000028588 96.2079 90.2622 ENSG00000144028 homo_sapiens ENSP00000317123 92.1816 86.3296 pundamilia_nyererei ENSPNYP00000023255 95.4435 89.3844 ENSG00000144028 homo_sapiens ENSP00000317123 95.1311 88.6704 mastacembelus_armatus ENSMAMP00000011645 94.7761 88.3396 ENSG00000144028 homo_sapiens ENSP00000317123 96.5356 90.6835 stegastes_partitus ENSSPAP00000002527 96.5356 90.6835 ENSG00000144028 homo_sapiens ENSP00000317123 96.7697 90.4026 oncorhynchus_tshawytscha ENSOTSP00005102807 96.7244 90.3603 ENSG00000144028 homo_sapiens ENSP00000317123 96.7697 90.5431 oncorhynchus_tshawytscha ENSOTSP00005075400 96.7244 90.5007 ENSG00000144028 homo_sapiens ENSP00000317123 96.5356 90.7772 acanthochromis_polyacanthus ENSAPOP00000008015 96.5356 90.7772 ENSG00000144028 homo_sapiens ENSP00000317123 99.485 97.6124 aquila_chrysaetos_chrysaetos ENSACCP00020014090 99.485 97.6124 ENSG00000144028 homo_sapiens ENSP00000317123 95.9738 89.8876 nothobranchius_furzeri ENSNFUP00015044286 95.9738 89.8876 ENSG00000144028 homo_sapiens ENSP00000317123 91.7603 85.721 cyprinodon_variegatus ENSCVAP00000014832 95.3307 89.0564 ENSG00000144028 homo_sapiens ENSP00000317123 96.3483 90.1217 denticeps_clupeoides ENSDCDP00000057066 96.2582 90.0374 ENSG00000144028 homo_sapiens ENSP00000317123 96.3951 90.6367 larimichthys_crocea ENSLCRP00005007345 96.3951 90.6367 ENSG00000144028 homo_sapiens ENSP00000317123 96.3951 90.309 takifugu_rubripes ENSTRUP00000003016 96.3951 90.309 ENSG00000144028 homo_sapiens ENSP00000317123 83.7547 81.2734 ficedula_albicollis ENSFALP00000001439 95.7709 92.9336 ENSG00000144028 homo_sapiens ENSP00000317123 20.9738 19.9906 hippocampus_comes ENSHCOP00000014247 96.1373 91.6309 ENSG00000144028 homo_sapiens ENSP00000317123 24.2509 22.4251 hippocampus_comes ENSHCOP00000014222 92.8315 85.8423 ENSG00000144028 homo_sapiens ENSP00000317123 96.2079 90.1685 cyprinus_carpio_carpio ENSCCRP00000068094 96.298 90.253 ENSG00000144028 homo_sapiens ENSP00000317123 96.3483 90.5431 cyprinus_carpio_carpio ENSCCRP00000066430 96.4386 90.6279 ENSG00000144028 homo_sapiens ENSP00000317123 99.4382 97.4251 coturnix_japonica ENSCJPP00005014153 99.4382 97.4251 ENSG00000144028 homo_sapiens ENSP00000317123 82.7247 77.2472 poecilia_latipinna ENSPLAP00000004842 95.9804 89.6252 ENSG00000144028 homo_sapiens ENSP00000317123 96.0206 89.9345 sinocyclocheilus_grahami ENSSGRP00000098498 96.1106 90.0187 ENSG00000144028 homo_sapiens ENSP00000317123 94.7097 88.9981 sinocyclocheilus_grahami ENSSGRP00000082485 95.6954 89.9243 ENSG00000144028 homo_sapiens ENSP00000317123 82.4906 77.294 maylandia_zebra ENSMZEP00005014339 95.1404 89.1469 ENSG00000144028 homo_sapiens ENSP00000317123 86.2828 79.4476 tetraodon_nigroviridis ENSTNIP00000006950 92.7996 85.4481 ENSG00000144028 homo_sapiens ENSP00000317123 96.4419 91.1049 paramormyrops_kingsleyae ENSPKIP00000036075 96.3968 91.0622 ENSG00000144028 homo_sapiens ENSP00000317123 96.8165 91.7603 scleropages_formosus ENSSFOP00015062157 96.7712 91.7174 ENSG00000144028 homo_sapiens ENSP00000317123 98.2678 95.0843 leptobrachium_leishanense ENSLLEP00000013587 98.3138 95.1288 ENSG00000144028 homo_sapiens ENSP00000317123 96.0674 90.3558 scophthalmus_maximus ENSSMAP00000008952 96.0674 90.3558 ENSG00000144028 homo_sapiens ENSP00000317123 96.4888 90.4494 oryzias_melastigma ENSOMEP00000028629 96.4888 90.4494
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000354 involved_in cis assembly of pre-catalytic spliceosome 1 IC Homo_sapiens(9606) Process GO:0000388 involved_in spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) 2 IBA,IDA Homo_sapiens(9606) Process GO:0000398 involved_in mRNA splicing, via spliceosome 4 IC,IDA,NAS,TAS Homo_sapiens(9606) Process GO:0001649 involved_in osteoblast differentiation 1 HDA Homo_sapiens(9606) Process GO:0003723 enables RNA binding 1 HDA Homo_sapiens(9606) Function GO:0003724 enables RNA helicase activity 3 IBA,IDA,TAS Homo_sapiens(9606) Function GO:0004386 enables helicase activity 1 IDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005524 enables ATP binding 1 IEA Homo_sapiens(9606) Function GO:0005634 located_in nucleus 2 IDA,NAS Homo_sapiens(9606) Component GO:0005654 located_in nucleoplasm 2 IDA,TAS Homo_sapiens(9606) Component GO:0005681 part_of spliceosomal complex 2 IBA,IDA Homo_sapiens(9606) Component GO:0005682 part_of U5 snRNP 1 IDA Homo_sapiens(9606) Component GO:0016020 located_in membrane 1 HDA Homo_sapiens(9606) Component GO:0016887 enables ATP hydrolysis activity 1 IEA Homo_sapiens(9606) Function GO:0042802 enables identical protein binding 1 IPI Homo_sapiens(9606) Function GO:0046540 part_of U4/U6 x U5 tri-snRNP complex 2 IDA,IPI Homo_sapiens(9606) Component GO:0071005 part_of U2-type precatalytic spliceosome 1 IDA Homo_sapiens(9606) Component GO:0071006 part_of U2-type catalytic step 1 spliceosome 1 IDA Homo_sapiens(9606) Component GO:0071013 part_of catalytic step 2 spliceosome 1 IDA Homo_sapiens(9606) Component
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.
