RBPWorld - a comprehensive database of RNA Binding Proteins

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Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	SARS-COV-2
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Kinase
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000142149	Gene ID	30811	Accession	13326
Symbol	HUNK	Alias	NA	Full Name	hormonally up-regulated Neu-associated kinase
Status	Confidence	Length	171614 bases	Strand	Plus strand
Position	21 : 31873020 - 32044633	RNA binding domain	RIO1
Summary	Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and protein phosphorylation. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000411860	RIO1	PF01163	2.2e-05	1
ENSP00000270112	RIO1	PF01163	0.00015	1

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
HUNK-201	ENST00000270112	7680	714aa	ENSP00000270112
HUNK-202	ENST00000430354	486	162aa	ENSP00000411860
HUNK-204	ENST00000465574	832	No protein	-
HUNK-203	ENST00000439107	860	112aa	ENSP00000408219

Gene Model

Click here to download ENSG00000142149's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
2874	Hemoglobin A, Glycosylated	7.84783516711851E-5	17903298
12025	Neuroblastoma	7.73E-7	18463370
26501	Blood Pressure	5.6210000E-005	-
39203	Platelet Function Tests	2.0700000E-006	-
50540	Child Development Disorders, Pervasive	2.0214700E-005	-
50555	Child Development Disorders, Pervasive	4.3401000E-005	-
51264	Child Development Disorders, Pervasive	2.7675200E-005	-
51281	Child Development Disorders, Pervasive	6.0977400E-005	-
51993	Child Development Disorders, Pervasive	9.4000000E-005	-
53035	Interleukin-8	1.5900000E-005	-
64669	Immunoglobulins	8E-6	23382691
80235	Vitiligo	2E-6	19890347
82153	Logic	5E-7	21107309
93769	Diabetes Mellitus, Type 2	4E-6	21490949

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000142149's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0004674	enables protein serine/threonine kinase activity	1	IBA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005524	enables ATP binding	1	IEA	Homo_sapiens(9606)	Function
GO:0005737	is_active_in cytoplasm	1	IBA	Homo_sapiens(9606)	Component
GO:0006468	involved_in protein phosphorylation	1	IEA	Homo_sapiens(9606)	Process
GO:0007165	involved_in signal transduction	1	TAS	Homo_sapiens(9606)	Process
GO:0035556	involved_in intracellular signal transduction	1	IBA	Homo_sapiens(9606)	Process
GO:0106310	enables protein serine kinase activity	1	IEA	Homo_sapiens(9606)	Function

Expression