| RBP Type |
Canonical_RBPs |
| Diseases |
N.A. |
| Drug |
N.A. |
| Main interacting RNAs |
tRNA |
| Moonlighting functions |
N.A. |
| Localizations |
N.A. |
|
BulkPerturb-seq
|
|
| Ensembl ID | ENSG00000141642 | Gene ID |
55520 |
Accession |
14197 |
| Symbol |
ELAC1 |
Alias |
|
Full Name |
|
| Status |
Confidence |
Length |
20131 bases |
Strand |
Plus strand |
| Position |
18 : 50967991 - 50988121 |
RNA binding domain |
Lactamase_B_4 , Lactamase_B |
| Summary |
|
RNA binding domains (RBDs)
| Protein |
Domain |
Pfam ID |
E-value |
Domain number |
| ENSP00000464770 |
Lactamase_B_4 |
PF13691 |
2e-07 |
1 |
| ENSP00000464770 |
Lactamase_B |
PF00753 |
2.2e-10 |
2 |
| ENSP00000269466 |
Lactamase_B_4 |
PF13691 |
5.3e-07 |
1 |
| ENSP00000269466 |
Lactamase_B |
PF00753 |
5.7e-11 |
2 |
RNA binding proteomes (RBPomes)
| Pubmed ID |
Full Name |
Cell |
Author |
Time |
Doi |
Literatures on RNA binding capacity
| Pubmed ID |
Title |
Author |
Time |
Journal |
| 26805042 |
The Chemical Biology of Human Metallo-β-Lactamase Fold Proteins. |
Ilaria Pettinati |
2016-04-01 |
Trends in biochemical sciences |
| 17201907 |
Gene expression profiles of primary colorectal carcinomas, liver metastases, and carcinomatoses. |
Kristine Kleivi |
2007-01-03 |
Molecular cancer |
| 32075755 |
ELAC1 Repairs tRNAs Cleaved during Ribosome-Associated Quality Control. |
J C Matthew Yip |
2020-02-18 |
Cell reports |
| Name |
Transcript ID |
bp |
Protein |
Translation ID |
| ELAC1-203 |
ENST00000588577 |
694 |
88aa |
ENSP00000467389 |
| ELAC1-201 |
ENST00000269466 |
2211 |
363aa |
ENSP00000269466 |
| ELAC1-202 |
ENST00000586966 |
1505 |
No protein |
- |
| ELAC1-204 |
ENST00000591429 |
975 |
223aa |
ENSP00000464770 |
| Pathway ID |
Pathway Name |
Source |
| | |
| ensgID |
Trait |
pValue |
Pubmed ID |
| 14927 | Hemoglobin A, Glycosylated | 6.2800000E-005 | 19875614 |
| 83606 | Cytokines | 2E-7 | 22610502 |
| 83607 | Vaccine Potency | 2E-7 | 22610502 |
| 99392 | Multiple Sclerosis | 8E-7 | 25616667 |
| 99393 | Oligoclonal Bands | 8E-7 | 25616667 |
| ensgID | SNP | Chromosome | Position |
Trait | PubmedID | Or or BEAT |
EFO ID |
|---|
Protein-Protein Interaction (PPI)
| Ensembl ID |
Source |
Target |
| Species |
Protein ID |
Perc_pos |
Perc_id |
Species |
Protein ID |
Perc_pos |
Perc_id |
| Ensembl ID |
Source |
Target |
| Species |
Protein ID |
Perc_pos |
Perc_id |
Species |
Protein ID |
Perc_pos |
Perc_id |
| Go ID |
Go term |
No. evidence |
Entries |
Species |
Category |
| GO:0004549 | enables tRNA-specific ribonuclease activity | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0005634 | is_active_in nucleus | 2 | IBA,IDA | Homo_sapiens(9606) | Component |
| GO:0005654 | located_in nucleoplasm | 1 | IDA | Homo_sapiens(9606) | Component |
| GO:0005829 | located_in cytosol | 1 | IDA | Homo_sapiens(9606) | Component |
| GO:0042780 | involved_in tRNA 3-end processing | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0042781 | enables 3-tRNA processing endoribonuclease activity | 1 | IBA | Homo_sapiens(9606) | Function |
| GO:0046872 | enables metal ion binding | 1 | IEA | Homo_sapiens(9606) | Function |
