RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000141526	Gene ID	9123	Accession	10924
Symbol	SLC16A3	Alias	MCT3;MCT4;MCT3;MCT4;MCT-3;MCT-4	Full Name	solute carrier family 16 member 3
Status	Confidence	Length	43196 bases	Strand	Plus strand
Position	17 : 82217934 - 82261129	RNA binding domain	N.A.
Summary	Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM, Mar 2008]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
SLC16A3-208	ENST00000580098	2676	410aa	ENSP00000463880
SLC16A3-216	ENST00000584689	2667	465aa	ENSP00000464625
SLC16A3-202	ENST00000392341	2659	465aa	ENSP00000376152
SLC16A3-211	ENST00000581642	557	No protein	-
SLC16A3-213	ENST00000582743	2599	465aa	ENSP00000462405
SLC16A3-215	ENST00000583444	2882	No protein	-
SLC16A3-217	ENST00000584781	562	No protein	-
SLC16A3-205	ENST00000578684	2439	417aa	ENSP00000463912
SLC16A3-203	ENST00000577650	2503	439aa	ENSP00000463063
SLC16A3-204	ENST00000578574	958	No protein	-
SLC16A3-207	ENST00000579572	863	No protein	-
SLC16A3-212	ENST00000582715	279	79aa	ENSP00000464326
SLC16A3-201	ENST00000392339	2662	465aa	ENSP00000376150
SLC16A3-210	ENST00000581287	4830	465aa	ENSP00000463978
SLC16A3-218	ENST00000617373	2636	465aa	ENSP00000483212
SLC16A3-209	ENST00000580189	2711	465aa	ENSP00000464112
SLC16A3-219	ENST00000619321	2603	465aa	ENSP00000482013
SLC16A3-206	ENST00000578810	678	No protein	-
SLC16A3-214	ENST00000583025	955	306aa	ENSP00000463005

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005886	located_in plasma membrane	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0008028	enables monocarboxylic acid transmembrane transporter activity	1	IBA	Homo_sapiens(9606)	Function
GO:0015650	enables lactate:proton symporter activity	1	IDA	Homo_sapiens(9606)	Function
GO:0015718	involved_in monocarboxylic acid transport	1	IBA	Homo_sapiens(9606)	Process
GO:0016020	located_in membrane	1	TAS	Homo_sapiens(9606)	Component
GO:0016323	located_in basolateral plasma membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0016324	located_in apical plasma membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0016328	located_in lateral plasma membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0030163	involved_in protein catabolic process	1	IDA	Homo_sapiens(9606)	Process
GO:0031965	located_in nuclear membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0035873	involved_in lactate transmembrane transport	1	IDA	Homo_sapiens(9606)	Process
GO:0042867	involved_in pyruvate catabolic process	1	IEA	Homo_sapiens(9606)	Process
GO:0045202	is_active_in synapse	1	IDA	Homo_sapiens(9606)	Component
GO:0050833	enables pyruvate transmembrane transporter activity	1	IDA	Homo_sapiens(9606)	Function
GO:1901475	involved_in pyruvate transmembrane transport	1	IDA	Homo_sapiens(9606)	Process