Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs tRNA
Moonlighting functions Transmemebrane
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000141378 Gene ID 51651 Accession 24265
Symbol PTRH2 Alias PTH;BIT1;PTH2;PTH2;CFAP37;IMNEPD;CGI-147 Full Name peptidyl-tRNA hydrolase 2
Status Confidence Length 10319 bases Strand Minus strand
Position 17 : 59697308 - 59707626 RNA binding domain PTH2
Summary The protein encoded by this gene is a mitochondrial protein with two putative domains, an N-terminal mitochondrial localization sequence, and a UPF0099 domain. In vitro assays suggest that this protein possesses peptidyl-tRNA hydrolase activity, to release the peptidyl moiety from tRNA, thereby preventing the accumulation of dissociated peptidyl-tRNA that could reduce the efficiency of translation. This protein also plays a role regulating cell survival and death. It promotes survival as part of an integrin-signaling pathway for cells attached to the extracellular matrix (ECM), but also promotes apoptosis in cells that have lost their attachment to the ECM, a process called anoikos. After loss of cell attachment to the ECM, this protein is phosphorylated, is released from the mitochondria into the cytosol, and promotes caspase-independent apoptosis through interactions with transcriptional regulators. This gene has been implicated in the development and progression of tumors, and mutations in this gene have been associated with an infantile multisystem neurologic, endocrine, and pancreatic disease (INMEPD) characterized by intellectual disability, postnatal microcephaly, progressive cerebellar atrophy, hearing impairment, polyneuropathy, failure to thrive, and organ fibrosis with exocrine pancreas insufficiency (PMID: 25574476). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000376758 PTH2 PF01981 4.1e-47 1
ENSP00000464327 PTH2 PF01981 4.1e-47 1
ENSP00000387180 PTH2 PF01981 4.2e-47 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
PTRH2-205 ENST00000587935 409 No protein -
PTRH2-201 ENST00000393038 731 179aa ENSP00000376758
PTRH2-202 ENST00000409433 2246 180aa ENSP00000387180
PTRH2-203 ENST00000470557 4114 179aa ENSP00000464327
PTRH2-204 ENST00000579915 531 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000141378

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000141378homo_sapiensENSP0000037675898.32497.7654nomascus_leucogenysENSNLEP0000000092297.777897.2222
ENSG00000141378homo_sapiensENSP00000376758100100pan_paniscusENSPPAP0000001783899.444499.4444
ENSG00000141378homo_sapiensENSP0000037675898.882798.324pongo_abeliiENSPPYP0000000989098.882798.324
ENSG00000141378homo_sapiensENSP00000376758100100pan_troglodytesENSPTRP0000001608099.444499.4444
ENSG00000141378homo_sapiensENSP0000037675899.441398.8827gorilla_gorillaENSGGOP0000002368498.888998.3333
ENSG00000141378homo_sapiensENSP0000037675884.357575.419ornithorhynchus_anatinusENSOANP0000001356155.311449.4506
ENSG00000141378homo_sapiensENSP0000037675885.474977.6536sarcophilus_harrisiiENSSHAP0000003625385.474977.6536
ENSG00000141378homo_sapiensENSP0000037675889.385584.3575choloepus_hoffmanniENSCHOP0000000397689.385584.3575
ENSG00000141378homo_sapiensENSP0000037675887.709581.5642dasypus_novemcinctusENSDNOP0000001791887.709581.5642
ENSG00000141378homo_sapiensENSP0000037675895.530792.1788callithrix_jacchusENSCJAP000000026799591.6667
ENSG00000141378homo_sapiensENSP0000037675898.32496.648cercocebus_atysENSCATP0000004142397.777896.1111
ENSG00000141378homo_sapiensENSP0000037675898.882796.648macaca_fascicularisENSMFAP0000000113576.956575.2174
ENSG00000141378homo_sapiensENSP0000037675898.882797.2067macaca_mulattaENSMMUP0000006838276.956575.6522
ENSG00000141378homo_sapiensENSP0000037675898.882797.2067macaca_nemestrinaENSMNEP0000002731898.333396.6667
ENSG00000141378homo_sapiensENSP0000037675898.882797.2067papio_anubisENSPANP0000002039498.333396.6667
ENSG00000141378homo_sapiensENSP0000037675898.32496.648mandrillus_leucophaeusENSMLEP0000000818697.777896.1111
ENSG00000141378homo_sapiensENSP0000037675888.268278.771tursiops_truncatusENSTTRP0000001631488.268278.771
ENSG00000141378homo_sapiensENSP0000037675892.737488.2682vulpes_vulpesENSVVUP0000002469392.737488.2682
ENSG00000141378homo_sapiensENSP0000037675885.474978.2123mus_spretusMGP_SPRETEiJ_P003041884.530477.3481
ENSG00000141378homo_sapiensENSP0000037675890.502884.9162equus_asinusENSEASP0000505806090.502884.9162
ENSG00000141378homo_sapiensENSP0000037675892.178884.3575capra_hircusENSCHIP0000000613992.178884.3575
ENSG00000141378homo_sapiensENSP0000037675892.178886.0335loxodonta_africanaENSLAFP0000002471192.178886.0335
ENSG00000141378homo_sapiensENSP0000037675891.620188.8268panthera_leoENSPLOP0000001122491.620188.8268
ENSG00000141378homo_sapiensENSP0000037675892.178887.7095ailuropoda_melanoleucaENSAMEP0000001206592.178887.7095
ENSG00000141378homo_sapiensENSP0000037675891.620184.3575bos_indicus_hybridENSBIXP0000502208491.620184.3575
ENSG00000141378homo_sapiensENSP0000037675889.944183.7989oryctolagus_cuniculusENSOCUP0000002392986.096380.2139
ENSG00000141378homo_sapiensENSP0000037675890.502884.3575equus_caballusENSECAP0000008235982.233576.6497
ENSG00000141378homo_sapiensENSP0000037675892.737488.2682canis_lupus_familiarisENSCAFP0084503571592.737488.2682
ENSG00000141378homo_sapiensENSP0000037675891.620188.8268panthera_pardusENSPPRP0000002720791.620188.8268
ENSG00000141378homo_sapiensENSP0000037675892.178887.1508marmota_marmota_marmotaENSMMMP0000002293884.615480
ENSG00000141378homo_sapiensENSP0000037675889.385583.7989balaenoptera_musculusENSBMSP0001002720589.385583.7989
ENSG00000141378homo_sapiensENSP0000037675889.385583.2402cavia_porcellusENSCPOP0000002240989.385583.2402
ENSG00000141378homo_sapiensENSP0000037675891.620187.1508felis_catusENSFCAP0000001551191.620187.1508
ENSG00000141378homo_sapiensENSP0000037675892.737488.2682ursus_americanusENSUAMP0000001194787.368483.1579
ENSG00000141378homo_sapiensENSP0000037675888.826884.3575ursus_americanusENSUAMP0000001195190.857186.2857
ENSG00000141378homo_sapiensENSP0000037675888.268279.3296monodelphis_domesticaENSMODP0000005072345.142940.5714
ENSG00000141378homo_sapiensENSP0000037675892.178884.9162bison_bison_bisonENSBBBP0000000394492.178884.9162
ENSG00000141378homo_sapiensENSP0000037675888.268279.3296monodon_monocerosENSMMNP0001502538188.268279.3296
ENSG00000141378homo_sapiensENSP0000037675890.502885.4749sus_scrofaENSSSCP0000001872190.502885.4749
ENSG00000141378homo_sapiensENSP0000037675889.944183.7989microcebus_murinusENSMICP0000003907889.444483.3333
ENSG00000141378homo_sapiensENSP0000037675876.536367.5978microcebus_murinusENSMICP0000004416383.536673.7805
ENSG00000141378homo_sapiensENSP0000037675891.061582.6816octodon_degusENSODEP0000002660991.061582.6816
ENSG00000141378homo_sapiensENSP0000037675888.826881.5642jaculus_jaculusENSJJAP0000001826389.325882.0225
ENSG00000141378homo_sapiensENSP0000037675872.06766.4804jaculus_jaculusENSJJAP000000124088679.3333
ENSG00000141378homo_sapiensENSP0000037675892.178884.3575ovis_aries_rambouilletENSOARP0002001645492.178884.3575
ENSG00000141378homo_sapiensENSP0000037675892.737488.2682ursus_maritimusENSUMAP0000003144992.737488.2682
ENSG00000141378homo_sapiensENSP0000037675888.826882.1229ochotona_princepsENSOPRP0000001614888.826882.1229
ENSG00000141378homo_sapiensENSP0000037675888.268279.3296delphinapterus_leucasENSDLEP0000001013888.268279.3296
ENSG00000141378homo_sapiensENSP0000037675889.385583.7989physeter_catodonENSPCTP0000502957589.385583.7989
ENSG00000141378homo_sapiensENSP0000037675885.474978.2123mus_caroliMGP_CAROLIEiJ_P002900984.530477.3481
ENSG00000141378homo_sapiensENSP0000037675885.474978.2123mus_musculusENSMUSP0000010365684.530477.3481
ENSG00000141378homo_sapiensENSP0000037675887.709582.1229dipodomys_ordiiENSDORP0000002596687.709582.1229
ENSG00000141378homo_sapiensENSP0000037675892.737489.3855mustela_putorius_furoENSMPUP0000001950092.737489.3855
ENSG00000141378homo_sapiensENSP0000037675896.089492.7374aotus_nancymaaeENSANAP0000000692695.555692.2222
ENSG00000141378homo_sapiensENSP0000037675896.089492.1788saimiri_boliviensis_boliviensisENSSBOP0000000858695.555691.6667
ENSG00000141378homo_sapiensENSP0000037675889.944184.9162vicugna_pacosENSVPAP0000000871289.944184.9162
ENSG00000141378homo_sapiensENSP0000037675898.32497.2067chlorocebus_sabaeusENSCSAP0000001745398.32497.2067
ENSG00000141378homo_sapiensENSP0000037675886.592278.2123mesocricetus_auratusENSMAUP0000002573485.635477.3481
ENSG00000141378homo_sapiensENSP0000037675887.709578.771phocoena_sinusENSPSNP0000001969487.709578.771
ENSG00000141378homo_sapiensENSP0000037675890.502885.4749camelus_dromedariusENSCDRP0000500698190.502885.4749
ENSG00000141378homo_sapiensENSP0000037675892.737489.9441carlito_syrichtaENSTSYP0000002206092.222289.4444
ENSG00000141378homo_sapiensENSP0000037675891.620188.8268panthera_tigris_altaicaENSPTIP0000000193991.620188.8268
ENSG00000141378homo_sapiensENSP0000037675873.184462.0112rattus_norvegicusENSRNOP0000008431559.00950
ENSG00000141378homo_sapiensENSP0000037675890.502886.0335prolemur_simusENSPSMP000000185449085.5556
ENSG00000141378homo_sapiensENSP0000037675886.592279.3296microtus_ochrogasterENSMOCP0000002164485.635478.453
ENSG00000141378homo_sapiensENSP0000037675885.474978.2123peromyscus_maniculatus_bairdiiENSPEMP000000287328577.7778
ENSG00000141378homo_sapiensENSP0000037675892.178884.9162bos_mutusENSBMUP0000000617892.178884.9162
ENSG00000141378homo_sapiensENSP0000037675876.536368.7151mus_spicilegusENSMSIP0000001374579.651271.5116
ENSG00000141378homo_sapiensENSP0000037675885.474978.2123mus_spicilegusENSMSIP0000001113184.530477.3481
ENSG00000141378homo_sapiensENSP0000037675887.150879.8883cricetulus_griseus_chok1gshdENSCGRP0000100972486.187879.0055
ENSG00000141378homo_sapiensENSP0000037675891.061586.0335pteropus_vampyrusENSPVAP0000000145391.061586.0335
ENSG00000141378homo_sapiensENSP0000037675892.737486.5922myotis_lucifugusENSMLUP0000002256792.737486.5922
ENSG00000141378homo_sapiensENSP0000037675885.474976.5363vombatus_ursinusENSVURP000100162848576.1111
ENSG00000141378homo_sapiensENSP0000037675878.77169.8324rhinolophus_ferrumequinumENSRFEP0001000236482.941273.5294
ENSG00000141378homo_sapiensENSP0000037675891.061586.5922rhinolophus_ferrumequinumENSRFEP0001001517091.061586.5922
ENSG00000141378homo_sapiensENSP0000037675892.737488.8268neovison_visonENSNVIP0000000251392.737488.8268
ENSG00000141378homo_sapiensENSP0000037675892.178884.9162bos_taurusENSBTAP0000002221292.178884.9162
ENSG00000141378homo_sapiensENSP0000037675861.452555.3073heterocephalus_glaber_femaleENSHGLP0000004415782.089673.8806
ENSG00000141378homo_sapiensENSP0000037675898.882797.7654rhinopithecus_bietiENSRBIP0000001991698.333397.2222
ENSG00000141378homo_sapiensENSP0000037675892.737488.2682canis_lupus_dingoENSCAFP0002003413492.737488.2682
ENSG00000141378homo_sapiensENSP0000037675891.061586.5922sciurus_vulgarisENSSVLP0000500780391.061586.5922
ENSG00000141378homo_sapiensENSP0000037675889.385577.6536phascolarctos_cinereusENSPCIP0000002939586.021574.7312
ENSG00000141378homo_sapiensENSP0000037675892.178884.3575procavia_capensisENSPCAP0000001059592.178884.3575
ENSG00000141378homo_sapiensENSP0000037675890.502882.6816nannospalax_galiliENSNGAP0000000806490.502882.6816
ENSG00000141378homo_sapiensENSP0000037675892.178884.9162bos_grunniensENSBGRP0000003391892.178884.9162
ENSG00000141378homo_sapiensENSP0000037675891.061583.7989chinchilla_lanigeraENSCLAP0000001655091.061583.7989
ENSG00000141378homo_sapiensENSP0000037675890.502884.3575cervus_hanglu_yarkandensisENSCHYP0000000060990.502884.3575
ENSG00000141378homo_sapiensENSP0000037675891.061587.1508catagonus_wagneriENSCWAP0000002033791.061587.1508
ENSG00000141378homo_sapiensENSP0000037675889.944184.9162ictidomys_tridecemlineatusENSSTOP0000002262689.944184.9162
ENSG00000141378homo_sapiensENSP0000037675891.620187.1508otolemur_garnettiiENSOGAP0000001602591.620187.1508
ENSG00000141378homo_sapiensENSP0000037675887.150877.6536otolemur_garnettiiENSOGAP0000002095387.640478.0899
ENSG00000141378homo_sapiensENSP0000037675896.089492.7374cebus_imitatorENSCCAP0000000364195.555692.2222
ENSG00000141378homo_sapiensENSP0000037675891.620186.5922urocitellus_parryiiENSUPAP0001000590084.102679.4872
ENSG00000141378homo_sapiensENSP0000037675892.178885.4749moschus_moschiferusENSMMSP0000002300292.178885.4749
ENSG00000141378homo_sapiensENSP0000037675898.882797.7654rhinopithecus_roxellanaENSRROP0000002863898.333397.2222
ENSG00000141378homo_sapiensENSP0000037675884.916277.095mus_pahariMGP_PahariEiJ_P003572683.977976.2431
ENSG00000141378homo_sapiensENSP0000037675890.502884.9162propithecus_coquereliENSPCOP000000051659084.4444
ENSG00000141378homo_sapiensENSP0000037675857.541941.3408drosophila_melanogasterFBpp031196855.376339.7849
ENSG00000141378homo_sapiensENSP0000037675862.569852.514ciona_intestinalisENSCINP0000002512067.469956.6265
ENSG00000141378homo_sapiensENSP0000037675855.307343.5754petromyzon_marinusENSPMAP0000000967258.235345.8824
ENSG00000141378homo_sapiensENSP0000037675867.039151.9553petromyzon_marinusENSPMAP0000001120666.298351.3812
ENSG00000141378homo_sapiensENSP0000037675869.273754.7486eptatretus_burgeriENSEBUP0000000577769.662955.0562
ENSG00000141378homo_sapiensENSP0000037675881.564269.8324callorhinchus_miliiENSCMIP0000004477279.781468.306
ENSG00000141378homo_sapiensENSP0000037675878.212366.4804latimeria_chalumnaeENSLACP0000001165578.212366.4804
ENSG00000141378homo_sapiensENSP0000037675879.329668.7151lepisosteus_oculatusENSLOCP0000002153182.080971.0983
ENSG00000141378homo_sapiensENSP0000037675872.625763.1285clupea_harengusENSCHAP0000004942669.148960.1064
ENSG00000141378homo_sapiensENSP0000037675877.09567.0391danio_rerioENSDARP0000011851178.409168.1818
ENSG00000141378homo_sapiensENSP0000037675878.212369.8324carassius_auratusENSCARP0000013375580.459871.8391
ENSG00000141378homo_sapiensENSP0000037675877.653668.1564carassius_auratusENSCARP0000002457280.81470.9302
ENSG00000141378homo_sapiensENSP0000037675877.653668.7151carassius_auratusENSCARP0000003401780.81471.5116
ENSG00000141378homo_sapiensENSP0000037675876.536366.4804astyanax_mexicanusENSAMXP0000002626181.065170.4142
ENSG00000141378homo_sapiensENSP0000037675874.860362.5698ictalurus_punctatusENSIPUP0000002823775.706263.2768
ENSG00000141378homo_sapiensENSP0000037675877.09567.5978esox_luciusENSELUP0000002420968.316859.901
ENSG00000141378homo_sapiensENSP0000037675873.184464.2458electrophorus_electricusENSEEEP0000000463380.864270.9877
ENSG00000141378homo_sapiensENSP0000037675877.653667.5978oncorhynchus_kisutchENSOKIP0000503715372.020762.6943
ENSG00000141378homo_sapiensENSP0000037675878.77167.5978oncorhynchus_mykissENSOMYP0000008901974.603264.0212
ENSG00000141378homo_sapiensENSP0000037675877.09566.4804salmo_salarENSSSAP0000014821079.310368.3908
ENSG00000141378homo_sapiensENSP0000037675859.776548.0447salmo_salarENSSSAP0000000091166.049453.0864
ENSG00000141378homo_sapiensENSP0000037675840.223533.5196salmo_truttaENSSTUP000000450707562.5
ENSG00000141378homo_sapiensENSP0000037675878.212367.5978salmo_truttaENSSTUP0000004395472.538962.6943
ENSG00000141378homo_sapiensENSP0000037675879.888368.1564gadus_morhuaENSGMOP0000002207683.139570.9302
ENSG00000141378homo_sapiensENSP0000037675878.77168.1564fundulus_heteroclitusENSFHEP0000003022176.216265.9459
ENSG00000141378homo_sapiensENSP0000037675878.212365.9218poecilia_reticulataENSPREP0000001332279.09666.6667
ENSG00000141378homo_sapiensENSP0000037675879.888368.1564xiphophorus_maculatusENSXMAP0000002014178.571467.033
ENSG00000141378homo_sapiensENSP0000037675875.977764.2458oryzias_latipesENSORLP0000001524779.532267.2515
ENSG00000141378homo_sapiensENSP0000037675878.212369.2737cyclopterus_lumpusENSCLMP0000503594278.212369.2737
ENSG00000141378homo_sapiensENSP0000037675877.09568.1564oreochromis_niloticusENSONIP0000002587980.701871.345
ENSG00000141378homo_sapiensENSP0000037675875.977766.4804haplochromis_burtoniENSHBUP0000001579680.473470.4142
ENSG00000141378homo_sapiensENSP0000037675876.536367.0391astatotilapia_callipteraENSACLP0000003828978.735668.9655
ENSG00000141378homo_sapiensENSP0000037675876.536366.4804sparus_aurataENSSAUP0001001956275.274765.3846
ENSG00000141378homo_sapiensENSP0000037675878.77170.3911lates_calcariferENSLCAP0001003525774.603266.6667
ENSG00000141378homo_sapiensENSP0000037675880.446968.1564xenopus_tropicalisENSXETP0000010856584.210571.345
ENSG00000141378homo_sapiensENSP0000037675879.329666.4804chrysemys_picta_belliiENSCPBP0000000781185.029971.2575
ENSG00000141378homo_sapiensENSP0000037675881.564268.7151sphenodon_punctatusENSSPUP0000002126782.485969.4915
ENSG00000141378homo_sapiensENSP0000037675879.888367.5978crocodylus_porosusENSCPRP0000501668183.139570.3488
ENSG00000141378homo_sapiensENSP0000037675881.564268.1564laticauda_laticaudataENSLLTP0000001776681.564268.1564
ENSG00000141378homo_sapiensENSP0000037675878.77167.0391notechis_scutatusENSNSUP0000001239081.976769.7674
ENSG00000141378homo_sapiensENSP0000037675878.77167.0391pseudonaja_textilisENSPTXP0000001503880.113668.1818
ENSG00000141378homo_sapiensENSP0000037675881.564269.2737gallus_gallusENSGALP0001004343385.380172.5146
ENSG00000141378homo_sapiensENSP0000037675881.005668.1564meleagris_gallopavoENSMGAP0000001642884.795371.345
ENSG00000141378homo_sapiensENSP0000037675878.212366.4804serinus_canariaENSSCAP0000001469680.924968.7861
ENSG00000141378homo_sapiensENSP0000037675878.212368.1564parus_majorENSPMJP0000002721777.777867.7778
ENSG00000141378homo_sapiensENSP0000037675878.212366.4804anolis_carolinensisENSACAP000000125408068
ENSG00000141378homo_sapiensENSP0000037675877.09568.1564neolamprologus_brichardiENSNBRP0000002324375.824267.033
ENSG00000141378homo_sapiensENSP0000037675878.212368.1564naja_najaENSNNAP0000001030679.545569.3182
ENSG00000141378homo_sapiensENSP0000037675881.005668.1564podarcis_muralisENSPMRP0000002356784.302370.9302
ENSG00000141378homo_sapiensENSP0000037675878.212367.0391geospiza_fortisENSGFOP0000001679876.923165.9341
ENSG00000141378homo_sapiensENSP0000037675878.212365.9218taeniopygia_guttataENSTGUP0000000783580.924968.2081
ENSG00000141378homo_sapiensENSP0000037675872.06762.0112erpetoichthys_calabaricusENSECRP0000001483777.710866.8675
ENSG00000141378homo_sapiensENSP0000037675881.564269.8324kryptolebias_marmoratusENSKMAP0000001782074.111763.4518
ENSG00000141378homo_sapiensENSP0000037675875.41964.2458salvator_merianaeENSSMRP0000001926274.175863.1868
ENSG00000141378homo_sapiensENSP0000037675878.212364.2458oryzias_javanicusENSOJAP0000003070277.348163.5359
ENSG00000141378homo_sapiensENSP0000037675875.41967.5978amphilophus_citrinellusENSACIP0000000577481.325372.8916
ENSG00000141378homo_sapiensENSP0000037675877.09568.1564dicentrarchus_labraxENSDLAP0000508224280.701871.345
ENSG00000141378homo_sapiensENSP0000037675877.09568.1564amphiprion_perculaENSAPEP0000002059371.87563.5417
ENSG00000141378homo_sapiensENSP0000037675875.977764.2458oryzias_sinensisENSOSIP0000004729479.532267.2515
ENSG00000141378homo_sapiensENSP0000037675880.446968.7151pelodiscus_sinensisENSPSIP000000097828068.3333
ENSG00000141378homo_sapiensENSP0000037675882.122968.1564gopherus_evgoodeiENSGEVP0000501498182.122968.1564
ENSG00000141378homo_sapiensENSP0000037675880.446967.0391chelonoidis_abingdoniiENSCABP0000001106679.120965.9341
ENSG00000141378homo_sapiensENSP0000037675877.653669.2737seriola_dumeriliENSSDUP0000002545872.020764.2487
ENSG00000141378homo_sapiensENSP0000037675877.09568.1564cottoperca_gobioENSCGOP0000003849180.701871.345
ENSG00000141378homo_sapiensENSP0000037675883.798972.067struthio_camelus_australisENSSCUP0000000800584.269772.4719
ENSG00000141378homo_sapiensENSP0000037675878.212365.9218anser_brachyrhynchusENSABRP0000000638480.459867.8161
ENSG00000141378homo_sapiensENSP0000037675879.888367.5978cynoglossus_semilaevisENSCSEP0000001809878.571466.4835
ENSG00000141378homo_sapiensENSP0000037675877.09564.8045poecilia_formosaENSPFOP0000002010877.966165.5367
ENSG00000141378homo_sapiensENSP0000037675877.09568.1564myripristis_murdjanENSMMDP0000502740680.701871.345
ENSG00000141378homo_sapiensENSP0000037675877.09568.1564sander_luciopercaENSSLUP0000000236680.701871.345
ENSG00000141378homo_sapiensENSP0000037675879.888369.8324strigops_habroptilaENSSHBP0000501703884.117673.5294
ENSG00000141378homo_sapiensENSP0000037675877.09568.7151amphiprion_ocellarisENSAOCP0000002087878.857170.2857
ENSG00000141378homo_sapiensENSP0000037675879.888367.0391terrapene_carolina_triunguisENSTMTP0000003129483.139569.7674
ENSG00000141378homo_sapiensENSP0000037675868.715153.0726hucho_huchoENSHHUP0000004894567.213151.9126
ENSG00000141378homo_sapiensENSP0000037675877.653667.5978hucho_huchoENSHHUP0000006779762.053654.0179
ENSG00000141378homo_sapiensENSP0000037675874.860366.4804betta_splendensENSBSLP0000005071678.362669.5906
ENSG00000141378homo_sapiensENSP0000037675881.564268.7151pygocentrus_nattereriENSPNAP0000000536680.66367.9558
ENSG00000141378homo_sapiensENSP0000037675877.09567.5978anabas_testudineusENSATEP0000000579980.701870.7602
ENSG00000141378homo_sapiensENSP0000037675858.100641.8994saccharomyces_cerevisiaeYBL057C5036.0577
ENSG00000141378homo_sapiensENSP0000037675878.212369.8324seriola_lalandi_dorsalisENSSLDP0000002676472.538964.7668
ENSG00000141378homo_sapiensENSP0000037675878.77170.3911labrus_bergyltaENSLBEP0000000531774.603266.6667
ENSG00000141378homo_sapiensENSP0000037675875.977766.4804pundamilia_nyerereiENSPNYP0000002911779.069869.186
ENSG00000141378homo_sapiensENSP0000037675877.09566.4804mastacembelus_armatusENSMAMP0000000768077.966167.2316
ENSG00000141378homo_sapiensENSP0000037675875.977767.0391stegastes_partitusENSSPAP0000000792876.836267.7966
ENSG00000141378homo_sapiensENSP0000037675877.09567.0391oncorhynchus_tshawytschaENSOTSP0000505406471.502662.1762
ENSG00000141378homo_sapiensENSP0000037675877.653668.7151acanthochromis_polyacanthusENSAPOP0000000700581.286671.9298
ENSG00000141378homo_sapiensENSP0000037675877.653668.7151acanthochromis_polyacanthusENSAPOP0000002534179.428670.2857
ENSG00000141378homo_sapiensENSP0000037675882.681671.5084aquila_chrysaetos_chrysaetosENSACCP0002001007582.222271.1111
ENSG00000141378homo_sapiensENSP0000037675877.09565.9218nothobranchius_furzeriENSNFUP0001503793180.701869.0059
ENSG00000141378homo_sapiensENSP0000037675876.536365.3631cyprinodon_variegatusENSCVAP0000001426876.536365.3631
ENSG00000141378homo_sapiensENSP0000037675874.301760.8939denticeps_clupeoidesENSDCDP000000405437662.2857
ENSG00000141378homo_sapiensENSP0000037675877.653669.8324larimichthys_croceaENSLCRP0000502992780.81472.6744
ENSG00000141378homo_sapiensENSP0000037675878.212370.3911takifugu_rubripesENSTRUP0000002076074.866367.3797
ENSG00000141378homo_sapiensENSP0000037675877.653666.4804ficedula_albicollisENSFALP0000001572679.885168.3908
ENSG00000141378homo_sapiensENSP0000037675874.860359.7765hippocampus_comesENSHCOP0000002362977.011561.4943
ENSG00000141378homo_sapiensENSP0000037675878.212368.1564cyprinus_carpio_carpioENSCCRP000001591858069.7143
ENSG00000141378homo_sapiensENSP0000037675863.687152.514cyprinus_carpio_carpioENSCCRP0000012874464.406853.1073
ENSG00000141378homo_sapiensENSP0000037675879.888366.4804coturnix_japonicaENSCJPP0000502166085.11970.8333
ENSG00000141378homo_sapiensENSP0000037675878.77167.0391poecilia_latipinnaENSPLAP0000001425779.66167.7966
ENSG00000141378homo_sapiensENSP0000037675877.09568.7151sinocyclocheilus_grahamiENSSGRP0000001010679.310370.6897
ENSG00000141378homo_sapiensENSP0000037675877.653668.1564sinocyclocheilus_grahamiENSSGRP0000001021578.531168.9266
ENSG00000141378homo_sapiensENSP0000037675875.977767.0391maylandia_zebraENSMZEP0000503129179.069869.7674
ENSG00000141378homo_sapiensENSP0000037675858.100649.162tetraodon_nigroviridisENSTNIP0000000802573.239461.9718
ENSG00000141378homo_sapiensENSP0000037675874.860364.2458tetraodon_nigroviridisENSTNIP0000000381477.456666.474
ENSG00000141378homo_sapiensENSP0000037675855.865945.8101tetraodon_nigroviridisENSTNIP0000000640670.92258.156
ENSG00000141378homo_sapiensENSP0000037675872.625763.6871tetraodon_nigroviridisENSTNIP0000000621875.144565.896
ENSG00000141378homo_sapiensENSP0000037675874.301764.8045paramormyrops_kingsleyaeENSPKIP0000000184681.595171.1656
ENSG00000141378homo_sapiensENSP0000037675874.301765.3631scleropages_formosusENSSFOP0001502258178.698269.2308
ENSG00000141378homo_sapiensENSP0000037675879.888364.8045leptobrachium_leishanenseENSLLEP0000000971680.337165.1685
ENSG00000141378homo_sapiensENSP0000037675877.09569.2737scophthalmus_maximusENSSMAP0000003871558.974452.9915
ENSG00000141378homo_sapiensENSP0000037675879.888365.9218oryzias_melastigmaENSOMEP0000002815577.717464.1304

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0004045enables aminoacyl-tRNA hydrolase activity2IBA,IMPHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005739is_active_in mitochondrion3IBA,IDA,IMPHomo_sapiens(9606)Component
GO:0005741located_in mitochondrial outer membrane1IDAHomo_sapiens(9606)Component
GO:0005829is_active_in cytosol2IBA,IMPHomo_sapiens(9606)Component
GO:0006915involved_in apoptotic process1IEAHomo_sapiens(9606)Process
GO:0010629involved_in negative regulation of gene expression1IMPHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:2000210involved_in positive regulation of anoikis2IBA,IMPHomo_sapiens(9606)Process
GO:2000811involved_in negative regulation of anoikis2IBA,IMPHomo_sapiens(9606)Process

Expression