Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-OC43FlavivirusesSARS-COV-2DengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq DataSet_01_116 DataSet_01_325

Description

Ensembl ID ENSG00000138757 Gene ID 9908 Accession 30291
Symbol G3BP2 Alias NA Full Name G3BP stress granule assembly factor 2
Status Confidence Length 82741 bases Strand Minus strand
Position 4 : 75641849 - 75724589 RNA binding domain NTF2 , RRM_1
Summary Enables RNA binding activity. Involved in positive regulation of stress granule assembly and protein homooligomerization. Located in cytoplasmic stress granule and cytosol. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000504764 RRM_1 PF00076 3.9e-13 1
ENSP00000504764 NTF2 PF02136 1.6e-06 2
ENSP00000503586 RRM_1 PF00076 4.1e-13 1
ENSP00000503586 NTF2 PF02136 1.9e-06 2
ENSP00000504599 RRM_1 PF00076 4.1e-13 1
ENSP00000504599 NTF2 PF02136 1.9e-06 2
ENSP00000503430 RRM_1 PF00076 4.7e-13 1
ENSP00000503430 NTF2 PF02136 4.9e-07 2
ENSP00000350518 RRM_1 PF00076 5.6e-13 1
ENSP00000350518 NTF2 PF02136 6.3e-32 2
ENSP00000502996 RRM_1 PF00076 5.6e-13 1
ENSP00000502996 NTF2 PF02136 6.3e-32 2
ENSP00000503209 RRM_1 PF00076 5.6e-13 1
ENSP00000503209 NTF2 PF02136 6.3e-32 2
ENSP00000503442 RRM_1 PF00076 5.6e-13 1
ENSP00000503442 NTF2 PF02136 6.3e-32 2
ENSP00000503496 RRM_1 PF00076 5.6e-13 1
ENSP00000503496 NTF2 PF02136 6.3e-32 2
ENSP00000503688 RRM_1 PF00076 5.6e-13 1
ENSP00000503688 NTF2 PF02136 6.3e-32 2
ENSP00000504025 RRM_1 PF00076 5.6e-13 1
ENSP00000504025 NTF2 PF02136 6.3e-32 2
ENSP00000504206 RRM_1 PF00076 5.6e-13 1
ENSP00000504206 NTF2 PF02136 6.3e-32 2
ENSP00000504363 RRM_1 PF00076 5.6e-13 1
ENSP00000504363 NTF2 PF02136 6.3e-32 2
ENSP00000504564 RRM_1 PF00076 5.6e-13 1
ENSP00000504564 NTF2 PF02136 6.3e-32 2
ENSP00000504588 RRM_1 PF00076 5.6e-13 1
ENSP00000504588 NTF2 PF02136 6.3e-32 2
ENSP00000504591 RRM_1 PF00076 5.6e-13 1
ENSP00000504591 NTF2 PF02136 6.3e-32 2
ENSP00000352738 RRM_1 PF00076 5.8e-13 1
ENSP00000352738 NTF2 PF02136 7.1e-32 2
ENSP00000379069 RRM_1 PF00076 5.8e-13 1
ENSP00000379069 NTF2 PF02136 7.1e-32 2
ENSP00000503228 RRM_1 PF00076 5.8e-13 1
ENSP00000503228 NTF2 PF02136 7.1e-32 2
ENSP00000503239 RRM_1 PF00076 5.8e-13 1
ENSP00000503239 NTF2 PF02136 7.1e-32 2
ENSP00000503355 RRM_1 PF00076 5.8e-13 1
ENSP00000503355 NTF2 PF02136 7.1e-32 2
ENSP00000503504 RRM_1 PF00076 5.8e-13 1
ENSP00000503504 NTF2 PF02136 7.1e-32 2
ENSP00000503669 RRM_1 PF00076 5.8e-13 1
ENSP00000503669 NTF2 PF02136 7.1e-32 2
ENSP00000503911 RRM_1 PF00076 5.8e-13 1
ENSP00000503911 NTF2 PF02136 7.1e-32 2
ENSP00000503943 RRM_1 PF00076 5.8e-13 1
ENSP00000503943 NTF2 PF02136 7.1e-32 2
ENSP00000504101 RRM_1 PF00076 5.8e-13 1
ENSP00000504101 NTF2 PF02136 7.1e-32 2
ENSP00000504159 RRM_1 PF00076 5.8e-13 1
ENSP00000504159 NTF2 PF02136 7.1e-32 2
ENSP00000504316 RRM_1 PF00076 5.8e-13 1
ENSP00000504316 NTF2 PF02136 7.1e-32 2
ENSP00000504361 RRM_1 PF00076 5.8e-13 1
ENSP00000504361 NTF2 PF02136 7.1e-32 2
ENSP00000504371 RRM_1 PF00076 5.8e-13 1
ENSP00000504371 NTF2 PF02136 7.1e-32 2
ENSP00000504496 RRM_1 PF00076 5.8e-13 1
ENSP00000504496 NTF2 PF02136 7.1e-32 2
ENSP00000504523 RRM_1 PF00076 5.8e-13 1
ENSP00000504523 NTF2 PF02136 7.1e-32 2
ENSP00000504585 RRM_1 PF00076 5.8e-13 1
ENSP00000504585 NTF2 PF02136 7.1e-32 2
ENSP00000504698 RRM_1 PF00076 5.8e-13 1
ENSP00000504698 NTF2 PF02136 7.1e-32 2
ENSP00000503974 RRM_1 PF00076 0.00076 1
ENSP00000503473 RRM_1 PF00076 0.001 1
ENSP00000422748 NTF2 PF02136 4.5e-33 1
ENSP00000424522 NTF2 PF02136 1.2e-32 1
ENSP00000504413 NTF2 PF02136 2.1e-32 1
ENSP00000503456 NTF2 PF02136 5.1e-32 1
ENSP00000503675 NTF2 PF02136 5.1e-32 1
ENSP00000423960 NTF2 PF02136 6.4e-26 1
ENSP00000422614 NTF2 PF02136 9.1e-20 1
ENSP00000504486 NTF2 PF02136 1.1e-14 1
ENSP00000503641 NTF2 PF02136 5.6e-14 1
ENSP00000503026 NTF2 PF02136 1.1e-06 1
ENSP00000503985 NTF2 PF02136 1.1e-06 1
ENSP00000426311 NTF2 PF02136 0.00031 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
37219408 Stress granules sequester Alzheimer's disease-associated gene transcripts and regulate disease-related neuronal proteostasis. Kaoru Sato 2023-05-22 Aging
26287230 The Virus-Host Interplay: Biogenesis of +RNA Replication Complexes. R Colleen Reid 2015-08-06 Viruses
37398029 mRNA condensation fluidizes the cytoplasm. Ying Xie 2023-07-15 bioRxiv : the preprint server for biology
34782720 G3BP2 regulated by the lncRNA LINC01554 facilitates esophageal squamous cell carcinoma metastasis through stabilizing HDGF transcript. Yinli Zheng 2022-01-01 Oncogene
36034716 Identification of a non-canonical G3BP-binding sequence in a Mayaro virus nsP3 hypervariable domain. Aymeric Neyret 2022-01-01 Frontiers in cellular and infection microbiology
31896577 RNase L promotes the formation of unique ribonucleoprotein granules distinct from stress granules. M James Burke 2020-02-07 The Journal of biological chemistry
35576205 The structural context of posttranslational modifications at a proteome-wide scale. Isabell Bludau 2022-05-01 PLoS biology
36878903 USP7- and PRMT5-dependent G3BP2 stabilization drives de novo lipogenesis and tumorigenesis of HNSC. Nan Wang 2023-03-06 Cell death & disease
36336216 G3BP2: Structure and function. Ge Jin 2022-12-01 Pharmacological research
37425880 Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication. Zemin Yang 2023-06-30 bioRxiv : the preprint server for biology
33000280 Overexpression of G3BP1 facilitates the progression of colon cancer by activating β‑catenin signaling. Yuanzhi Li 2020-11-01 Molecular medicine reports
25653451 Stress granule components G3BP1 and G3BP2 play a proviral role early in Chikungunya virus replication. M E Florine Scholte 2015-04-01 Journal of virology
31501480 G3BP1 inhibits ubiquitinated protein aggregations induced by p62 and USP10. Sergei Anisimov 2019-09-09 Scientific reports
36851663 Pro-Viral and Anti-Viral Roles of the RNA-Binding Protein G3BP1. Kumar Aravinth Jayabalan 2023-02-06 Viruses
24321297 Regulation of PMP22 mRNA by G3BP1 affects cell proliferation in breast cancer cells. Sofia Winslow 2013-12-09 Molecular cancer
36274097 Leveraging patient derived models of FGFR2 fusion positive intrahepatic cholangiocarcinoma to identify synergistic therapies. E Michael Lidsky 2022-10-23 NPJ precision oncology
37425931 Identification of small molecule inhibitors of G3BP-driven stress granule formation. D Brian Freibaum 2023-06-28 bioRxiv : the preprint server for biology
24656821 Systematic identification of regulatory elements in conserved 3' UTRs of human transcripts. Panos Oikonomou 2014-04-10 Cell reports
27289443 Principles and Properties of Stress Granules. W S David Protter 2016-09-01 Trends in cell biology
33199441 RNA partitioning into stress granules is based on the summation of multiple interactions. Tyler Matheny 2021-02-01 RNA (New York, N.Y.)
34254825 RNA-Protein Interaction Analysis of SARS-CoV-2 5' and 3' Untranslated Regions Reveals a Role of Lysosome-Associated Membrane Protein-2a during Viral Infection. Rohit Verma 2021-08-31 mSystems
30326201 Differences between acute and chronic stress granules, and how these differences may impact function in human disease. C Lucas Reineke 2019-04-01 Biochemical pharmacology
36574355 Cytosolic stress granules relieve the ubiquitin-proteasome system in the nuclear compartment. Shanshan Xu 2023-02-01 The EMBO journal
31114027 UBAP2L arginine methylation by PRMT1 modulates stress granule assembly. Chuyu Huang 2020-01-01 Cell death and differentiation

Transcripts

Name Transcript ID bp Protein Translation ID
G3BP2-290 ENST00000679329 5811 No protein -
G3BP2-257 ENST00000677794 3957 63aa ENSP00000504312
G3BP2-240 ENST00000677171 5154 482aa ENSP00000503911
G3BP2-266 ENST00000678123 5195 482aa ENSP00000503504
G3BP2-275 ENST00000678578 5195 482aa ENSP00000503943
G3BP2-258 ENST00000677876 5110 449aa ENSP00000504206
G3BP2-231 ENST00000676839 5013 449aa ENSP00000503442
G3BP2-268 ENST00000678265 5151 482aa ENSP00000504159
G3BP2-255 ENST00000677727 4820 64aa ENSP00000503985
G3BP2-241 ENST00000677192 6181 No protein -
G3BP2-274 ENST00000678552 5142 449aa ENSP00000504588
G3BP2-225 ENST00000676584 5519 482aa ENSP00000504496
G3BP2-271 ENST00000678329 5060 424aa ENSP00000503430
G3BP2-260 ENST00000677889 5117 388aa ENSP00000503586
G3BP2-234 ENST00000677003 4880 64aa ENSP00000503026
G3BP2-233 ENST00000676974 5285 482aa ENSP00000503669
G3BP2-267 ENST00000678244 5095 355aa ENSP00000504764
G3BP2-273 ENST00000678447 5548 252aa ENSP00000504413
G3BP2-282 ENST00000678875 6379 No protein -
G3BP2-251 ENST00000677583 5189 449aa ENSP00000504564
G3BP2-253 ENST00000677606 5595 482aa ENSP00000503228
G3BP2-280 ENST00000678798 5456 482aa ENSP00000504585
G3BP2-254 ENST00000677620 5456 482aa ENSP00000504316
G3BP2-287 ENST00000679281 5211 449aa ENSP00000504025
G3BP2-245 ENST00000677333 5563 482aa ENSP00000503355
G3BP2-220 ENST00000676470 5515 449aa ENSP00000503688
G3BP2-286 ENST00000678971 5367 482aa ENSP00000504371
G3BP2-243 ENST00000677265 5398 449aa ENSP00000504591
G3BP2-265 ENST00000678122 5155 449aa ENSP00000504363
G3BP2-264 ENST00000678100 5385 482aa ENSP00000504698
G3BP2-263 ENST00000678062 5327 482aa ENSP00000503239
G3BP2-227 ENST00000676666 5390 449aa ENSP00000503496
G3BP2-203 ENST00000395719 4217 482aa ENSP00000379069
G3BP2-202 ENST00000359707 4321 482aa ENSP00000352738
G3BP2-235 ENST00000677060 4163 381aa ENSP00000503456
G3BP2-288 ENST00000679294 5011 No protein -
G3BP2-242 ENST00000677201 4240 482aa ENSP00000504523
G3BP2-261 ENST00000677952 4150 381aa ENSP00000503675
G3BP2-269 ENST00000678273 2788 449aa ENSP00000502996
G3BP2-237 ENST00000677125 2592 449aa ENSP00000503209
G3BP2-201 ENST00000357854 2609 449aa ENSP00000350518
G3BP2-250 ENST00000677566 2357 482aa ENSP00000504361
G3BP2-239 ENST00000677162 2330 482aa ENSP00000504101
G3BP2-262 ENST00000677970 1838 388aa ENSP00000504599
G3BP2-284 ENST00000678932 497 86aa ENSP00000503974
G3BP2-249 ENST00000677520 222 74aa ENSP00000503350
G3BP2-207 ENST00000507133 598 No protein -
G3BP2-246 ENST00000677426 256 85aa ENSP00000503473
G3BP2-277 ENST00000678642 256 10aa ENSP00000504331
G3BP2-211 ENST00000507947 665 No protein -
G3BP2-215 ENST00000510902 374 35aa ENSP00000426843
G3BP2-285 ENST00000678958 444 37aa ENSP00000503871
G3BP2-230 ENST00000676761 497 76aa ENSP00000503641
G3BP2-244 ENST00000677278 458 63aa ENSP00000504486
G3BP2-222 ENST00000676493 377 20aa ENSP00000503475
G3BP2-206 ENST00000503660 1071 198aa ENSP00000424522
G3BP2-252 ENST00000677597 188 62aa ENSP00000503615
G3BP2-232 ENST00000676926 369 48aa ENSP00000503807
G3BP2-256 ENST00000677733 222 No protein -
G3BP2-278 ENST00000678670 297 No protein -
G3BP2-205 ENST00000502654 546 No protein -
G3BP2-219 ENST00000515457 405 48aa ENSP00000425122
G3BP2-213 ENST00000509100 384 40aa ENSP00000426311
G3BP2-210 ENST00000507745 584 141aa ENSP00000422748
G3BP2-218 ENST00000513927 426 No protein -
G3BP2-216 ENST00000511146 577 115aa ENSP00000423960
G3BP2-208 ENST00000507252 567 102aa ENSP00000422614
G3BP2-209 ENST00000507701 678 No protein -
G3BP2-247 ENST00000677489 184 31aa ENSP00000504360
G3BP2-214 ENST00000509561 149 31aa ENSP00000424060
G3BP2-238 ENST00000677145 158 31aa ENSP00000504093
G3BP2-229 ENST00000676702 155 31aa ENSP00000504401
G3BP2-212 ENST00000508510 451 31aa ENSP00000423245
G3BP2-204 ENST00000499709 423 31aa ENSP00000422830
G3BP2-217 ENST00000511868 426 31aa ENSP00000421621
G3BP2-283 ENST00000678908 276 No protein -
G3BP2-221 ENST00000676485 265 No protein -
G3BP2-272 ENST00000678389 246 No protein -
G3BP2-226 ENST00000676641 197 No protein -
G3BP2-281 ENST00000678843 178 No protein -
G3BP2-259 ENST00000677888 162 No protein -
G3BP2-279 ENST00000678732 176 No protein -
G3BP2-248 ENST00000677515 162 No protein -
G3BP2-223 ENST00000676579 162 No protein -
G3BP2-289 ENST00000679325 168 No protein -
G3BP2-228 ENST00000676689 124 No protein -
G3BP2-236 ENST00000677094 2441 No protein -
G3BP2-276 ENST00000678620 151 No protein -
G3BP2-270 ENST00000678326 151 No protein -
G3BP2-224 ENST00000676580 151 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
67936Magnesium2E-625886283
87456Magnesium7E-625886283

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000138757homo_sapiensENSP0000034857879.184566.5236homo_sapiensENSP0000035273876.55664.3154

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000138757homo_sapiensENSP0000035273899.792599.7925nomascus_leucogenysENSNLEP0000000975799.792599.7925
ENSG00000138757homo_sapiensENSP00000352738100100pan_paniscusENSPPAP00000039267100100
ENSG00000138757homo_sapiensENSP00000352738100100pongo_abeliiENSPPYP00000025619100100
ENSG00000138757homo_sapiensENSP00000352738100100pan_troglodytesENSPTRP00000040810100100
ENSG00000138757homo_sapiensENSP00000352738100100gorilla_gorillaENSGGOP00000014586100100
ENSG00000138757homo_sapiensENSP0000035273897.095493.361ornithorhynchus_anatinusENSOANP0000003738697.297393.5551
ENSG00000138757homo_sapiensENSP0000035273898.132896.2656sarcophilus_harrisiiENSSHAP0000002729195.17193.3602
ENSG00000138757homo_sapiensENSP0000035273896.47393.9834notamacropus_eugeniiENSMEUP0000000376398.51795.9746
ENSG00000138757homo_sapiensENSP0000035273895.643295.2282choloepus_hoffmanniENSCHOP0000000474395.84295.4262
ENSG00000138757homo_sapiensENSP0000035273867.842360.3734dasypus_novemcinctusENSDNOP0000002856278.04369.4511
ENSG00000138757homo_sapiensENSP0000035273892.738691.9087erinaceus_europaeusENSEEUP0000001224392.738691.9087
ENSG00000138757homo_sapiensENSP0000035273898.755297.0954echinops_telfairiENSETEP0000001314598.960597.2973
ENSG00000138757homo_sapiensENSP0000035273899.792599.7925callithrix_jacchusENSCJAP0000008077099.792599.7925
ENSG00000138757homo_sapiensENSP00000352738100100cercocebus_atysENSCATP00000008509100100
ENSG00000138757homo_sapiensENSP00000352738100100macaca_fascicularisENSMFAP00000026656100100
ENSG00000138757homo_sapiensENSP0000035273899.792599.7925macaca_mulattaENSMMUP0000007207399.792599.7925
ENSG00000138757homo_sapiensENSP0000035273899.792599.7925macaca_nemestrinaENSMNEP0000004528599.792599.7925
ENSG00000138757homo_sapiensENSP00000352738100100papio_anubisENSPANP00000028675100100
ENSG00000138757homo_sapiensENSP00000352738100100mandrillus_leucophaeusENSMLEP00000007499100100
ENSG00000138757homo_sapiensENSP0000035273899.170197.9253tursiops_truncatusENSTTRP0000001308599.170197.9253
ENSG00000138757homo_sapiensENSP0000035273899.792598.7552vulpes_vulpesENSVVUP0000003345499.792598.7552
ENSG00000138757homo_sapiensENSP0000035273899.170198.3402mus_spretusMGP_SPRETEiJ_P007174299.170198.3402
ENSG00000138757homo_sapiensENSP0000035273810099.3776equus_asinusENSEASP0000504096510099.3776
ENSG00000138757homo_sapiensENSP0000035273899.377698.3402capra_hircusENSCHIP0000001186499.377698.3402
ENSG00000138757homo_sapiensENSP0000035273810099.1701loxodonta_africanaENSLAFP0000001752798.16797.3523
ENSG00000138757homo_sapiensENSP0000035273899.792598.9627panthera_leoENSPLOP0000000321599.792598.9627
ENSG00000138757homo_sapiensENSP0000035273899.792598.9627ailuropoda_melanoleucaENSAMEP0000001525399.792598.9627
ENSG00000138757homo_sapiensENSP0000035273899.377698.5477bos_indicus_hybridENSBIXP0000502166299.377698.5477
ENSG00000138757homo_sapiensENSP00000352738100100oryctolagus_cuniculusENSOCUP00000002832100100
ENSG00000138757homo_sapiensENSP0000035273810099.3776equus_caballusENSECAP0000008568410099.3776
ENSG00000138757homo_sapiensENSP0000035273899.792598.7552canis_lupus_familiarisENSCAFP0084503968699.792598.7552
ENSG00000138757homo_sapiensENSP0000035273899.792598.9627panthera_pardusENSPPRP0000001734899.792598.9627
ENSG00000138757homo_sapiensENSP0000035273810099.7925marmota_marmota_marmotaENSMMMP0000000765710099.7925
ENSG00000138757homo_sapiensENSP0000035273899.585198.7552balaenoptera_musculusENSBMSP0001000846299.792198.9605
ENSG00000138757homo_sapiensENSP0000035273898.962797.5104cavia_porcellusENSCPOP0000002705598.962797.5104
ENSG00000138757homo_sapiensENSP0000035273899.792598.9627felis_catusENSFCAP0000001688999.792598.9627
ENSG00000138757homo_sapiensENSP0000035273899.792598.9627ursus_americanusENSUAMP0000002241299.792598.9627
ENSG00000138757homo_sapiensENSP0000035273897.925396.0581monodelphis_domesticaENSMODP0000002397997.925396.0581
ENSG00000138757homo_sapiensENSP0000035273899.377698.5477bison_bison_bisonENSBBBP0000000942299.377698.5477
ENSG00000138757homo_sapiensENSP0000035273899.377698.1328monodon_monocerosENSMMNP0001502504799.377698.1328
ENSG00000138757homo_sapiensENSP0000035273899.377698.3402sus_scrofaENSSSCP0000005529999.584298.5447
ENSG00000138757homo_sapiensENSP0000035273899.585199.1701microcebus_murinusENSMICP0000004399999.585199.1701
ENSG00000138757homo_sapiensENSP0000035273877.385975.3112octodon_degusENSODEP0000000220394.910992.3664
ENSG00000138757homo_sapiensENSP0000035273898.962798.3402jaculus_jaculusENSJJAP0000001397998.962798.3402
ENSG00000138757homo_sapiensENSP0000035273896.265695.4357ovis_aries_rambouilletENSOARP0002000486899.357698.5011
ENSG00000138757homo_sapiensENSP0000035273899.792598.7552ursus_maritimusENSUMAP0000000893199.792598.7552
ENSG00000138757homo_sapiensENSP0000035273892.738692.5311ochotona_princepsENSOPRP0000000578299.333399.1111
ENSG00000138757homo_sapiensENSP0000035273899.377698.1328delphinapterus_leucasENSDLEP0000002137399.377698.1328
ENSG00000138757homo_sapiensENSP0000035273899.792598.9627physeter_catodonENSPCTP0000500620599.792598.9627
ENSG00000138757homo_sapiensENSP0000035273899.170198.3402mus_caroliMGP_CAROLIEiJ_P006908399.170198.3402
ENSG00000138757homo_sapiensENSP0000035273899.170198.3402mus_musculusENSMUSP0000012835399.170198.3402
ENSG00000138757homo_sapiensENSP0000035273899.377698.7552dipodomys_ordiiENSDORP0000001694199.171898.5507
ENSG00000138757homo_sapiensENSP0000035273899.585198.3402mustela_putorius_furoENSMPUP0000000896994.302693.1238
ENSG00000138757homo_sapiensENSP0000035273840.24937.7593aotus_nancymaaeENSANAP0000000118986.995581.6143
ENSG00000138757homo_sapiensENSP0000035273867.012563.4855aotus_nancymaaeENSANAP0000000022491.242986.4407
ENSG00000138757homo_sapiensENSP0000035273887.551986.3071aotus_nancymaaeENSANAP0000002851892.341491.0285
ENSG00000138757homo_sapiensENSP0000035273869.709567.2199saimiri_boliviensis_boliviensisENSSBOP0000002254088.421185.2632
ENSG00000138757homo_sapiensENSP0000035273899.585199.5851saimiri_boliviensis_boliviensisENSSBOP0000001386799.585199.5851
ENSG00000138757homo_sapiensENSP0000035273892.738692.1162vicugna_pacosENSVPAP0000000997192.738692.1162
ENSG00000138757homo_sapiensENSP0000035273893.153593.1535chlorocebus_sabaeusENSCSAP00000001024100100
ENSG00000138757homo_sapiensENSP0000035273890.663989.6266tupaia_belangeriENSTBEP0000000714697.982196.861
ENSG00000138757homo_sapiensENSP0000035273892.323791.9087tupaia_belangeriENSTBEP0000001067398.888998.4444
ENSG00000138757homo_sapiensENSP0000035273898.755297.7178mesocricetus_auratusENSMAUP0000000608298.755297.7178
ENSG00000138757homo_sapiensENSP0000035273899.377698.1328phocoena_sinusENSPSNP0000001100999.377698.1328
ENSG00000138757homo_sapiensENSP0000035273810099.3776camelus_dromedariusENSCDRP0000500088810099.3776
ENSG00000138757homo_sapiensENSP0000035273899.170198.3402carlito_syrichtaENSTSYP0000002975799.170198.3402
ENSG00000138757homo_sapiensENSP0000035273894.398393.7759panthera_tigris_altaicaENSPTIP0000002253597.849597.2043
ENSG00000138757homo_sapiensENSP0000035273898.547797.9253rattus_norvegicusENSRNOP0000000334698.547797.9253
ENSG00000138757homo_sapiensENSP0000035273899.377699.3776prolemur_simusENSPSMP0000001827799.377699.3776
ENSG00000138757homo_sapiensENSP0000035273899.377698.5477microtus_ochrogasterENSMOCP0000002321599.377698.5477
ENSG00000138757homo_sapiensENSP0000035273892.946191.9087sorex_araneusENSSARP0000000859399.555698.4444
ENSG00000138757homo_sapiensENSP0000035273821.161818.6722peromyscus_maniculatus_bairdiiENSPEMP0000003274056.04449.4506
ENSG00000138757homo_sapiensENSP0000035273847.095445.2282peromyscus_maniculatus_bairdiiENSPEMP0000001964297.008593.1624
ENSG00000138757homo_sapiensENSP0000035273899.377698.5477bos_mutusENSBMUP0000002267899.377698.5477
ENSG00000138757homo_sapiensENSP0000035273899.170198.3402mus_spicilegusENSMSIP0000002234599.170198.3402
ENSG00000138757homo_sapiensENSP0000035273898.547797.9253cricetulus_griseus_chok1gshdENSCGRP0000101739698.547797.9253
ENSG00000138757homo_sapiensENSP0000035273891.286390.0415pteropus_vampyrusENSPVAP0000000958691.85890.6054
ENSG00000138757homo_sapiensENSP0000035273892.323791.4938myotis_lucifugusENSMLUP0000000432699.109198.2183
ENSG00000138757homo_sapiensENSP0000035273896.88893.7759vombatus_ursinusENSVURP0001001264796.88893.7759
ENSG00000138757homo_sapiensENSP0000035273899.585198.9627rhinolophus_ferrumequinumENSRFEP0001003119199.585198.9627
ENSG00000138757homo_sapiensENSP0000035273899.377698.5477neovison_visonENSNVIP0000001852299.377698.5477
ENSG00000138757homo_sapiensENSP0000035273899.377698.5477bos_taurusENSBTAP0000006779899.377698.5477
ENSG00000138757homo_sapiensENSP0000035273899.792599.5851heterocephalus_glaber_femaleENSHGLP0000001769399.792599.5851
ENSG00000138757homo_sapiensENSP0000035273810099.7925rhinopithecus_bietiENSRBIP0000003899710099.7925
ENSG00000138757homo_sapiensENSP0000035273899.792598.7552canis_lupus_dingoENSCAFP0002001441799.792598.7552
ENSG00000138757homo_sapiensENSP0000035273899.792599.5851sciurus_vulgarisENSSVLP0000501601499.792599.5851
ENSG00000138757homo_sapiensENSP0000035273897.925395.6432phascolarctos_cinereusENSPCIP0000000852497.925395.6432
ENSG00000138757homo_sapiensENSP0000035273892.531191.7012procavia_capensisENSPCAP0000001414199.553698.6607
ENSG00000138757homo_sapiensENSP0000035273889.211688.5892nannospalax_galiliENSNGAP0000001258796.412695.7399
ENSG00000138757homo_sapiensENSP0000035273899.377698.5477bos_grunniensENSBGRP0000002838296.767795.9596
ENSG00000138757homo_sapiensENSP0000035273899.170198.7552chinchilla_lanigeraENSCLAP0000000461399.170198.7552
ENSG00000138757homo_sapiensENSP0000035273899.377698.3402cervus_hanglu_yarkandensisENSCHYP0000000412499.377698.3402
ENSG00000138757homo_sapiensENSP0000035273899.585198.3402catagonus_wagneriENSCWAP0000002435199.585198.3402
ENSG00000138757homo_sapiensENSP0000035273810099.7925ictidomys_tridecemlineatusENSSTOP0000001943210099.7925
ENSG00000138757homo_sapiensENSP0000035273892.738692.5311otolemur_garnettiiENSOGAP0000000013999.554699.3318
ENSG00000138757homo_sapiensENSP0000035273899.792599.7925cebus_imitatorENSCCAP0000001364499.792599.7925
ENSG00000138757homo_sapiensENSP0000035273872.406670.1245cebus_imitatorENSCCAP0000002589491.601188.7139
ENSG00000138757homo_sapiensENSP0000035273893.153590.8714cebus_imitatorENSCCAP0000000054095.127192.7966
ENSG00000138757homo_sapiensENSP0000035273899.792599.3776urocitellus_parryiiENSUPAP0001000577699.792599.3776
ENSG00000138757homo_sapiensENSP0000035273898.962798.1328moschus_moschiferusENSMMSP0000003029398.962798.1328
ENSG00000138757homo_sapiensENSP0000035273899.792599.7925rhinopithecus_roxellanaENSRROP0000003486699.792599.7925
ENSG00000138757homo_sapiensENSP0000035273893.36192.5311mus_pahariMGP_PahariEiJ_P003224495.33994.4915
ENSG00000138757homo_sapiensENSP0000035273899.585199.5851propithecus_coquereliENSPCOP0000000772599.585199.5851
ENSG00000138757homo_sapiensENSP0000035273838.381721.5768caenorhabditis_elegansK08F4.2.139.11221.9873
ENSG00000138757homo_sapiensENSP0000035273857.468942.3237drosophila_melanogasterFBpp031206440.144929.5652
ENSG00000138757homo_sapiensENSP0000035273855.601744.6058ciona_intestinalisENSCINP0000000984557.142945.8422
ENSG00000138757homo_sapiensENSP0000035273835.062229.8755petromyzon_marinusENSPMAP0000001083778.240766.6667
ENSG00000138757homo_sapiensENSP0000035273826.141122.4066eptatretus_burgeriENSEBUP0000002088750.602443.3735
ENSG00000138757homo_sapiensENSP0000035273888.381779.6681callorhinchus_miliiENSCMIP0000003796886.234877.7328
ENSG00000138757homo_sapiensENSP0000035273890.663985.0622latimeria_chalumnaeENSLACP0000000333790.852485.2391
ENSG00000138757homo_sapiensENSP0000035273887.344480.2905lepisosteus_oculatusENSLOCP0000001661783.697876.9384
ENSG00000138757homo_sapiensENSP0000035273886.72279.2531clupea_harengusENSCHAP0000006267882.608775.4941
ENSG00000138757homo_sapiensENSP0000035273883.19573.6515danio_rerioENSDARP0000004637579.092770.0197
ENSG00000138757homo_sapiensENSP0000035273883.6175.3112carassius_auratusENSCARP0000004653979.487271.5976
ENSG00000138757homo_sapiensENSP0000035273881.535374.2739astyanax_mexicanusENSAMXP0000004731377.362270.4724
ENSG00000138757homo_sapiensENSP0000035273880.497972.4066ictalurus_punctatusENSIPUP0000000511477.290869.5219
ENSG00000138757homo_sapiensENSP0000035273888.381780.4979esox_luciusENSELUP0000003635583.36675.9296
ENSG00000138757homo_sapiensENSP0000035273878.838269.7095electrophorus_electricusENSEEEP0000004808877.868968.8525
ENSG00000138757homo_sapiensENSP0000035273886.514579.8755oncorhynchus_kisutchENSOKIP0000509849581.445375.1953
ENSG00000138757homo_sapiensENSP0000035273886.514579.8755oncorhynchus_kisutchENSOKIP0000508095681.445375.1953
ENSG00000138757homo_sapiensENSP0000035273886.514579.8755oncorhynchus_mykissENSOMYP0000001669081.925375.6385
ENSG00000138757homo_sapiensENSP0000035273886.514579.8755oncorhynchus_mykissENSOMYP0000001663581.445375.1953
ENSG00000138757homo_sapiensENSP0000035273886.929580.083salmo_salarENSSSAP0000015178682.156975.6863
ENSG00000138757homo_sapiensENSP0000035273886.929580.083salmo_salarENSSSAP0000000138081.517575.0973
ENSG00000138757homo_sapiensENSP0000035273886.929580.083salmo_truttaENSSTUP0000004505381.676475.2437
ENSG00000138757homo_sapiensENSP0000035273886.307179.2531salmo_truttaENSSTUP0000001120182.213475.4941
ENSG00000138757homo_sapiensENSP0000035273888.174379.4606gadus_morhuaENSGMOP0000004375284.158475.8416
ENSG00000138757homo_sapiensENSP0000035273886.307180.083fundulus_heteroclitusENSFHEP0000001700181.728975.835
ENSG00000138757homo_sapiensENSP0000035273887.551980.2905poecilia_reticulataENSPREP0000000241583.399276.4822
ENSG00000138757homo_sapiensENSP0000035273887.551980.4979xiphophorus_maculatusENSXMAP0000002050982.907776.2279
ENSG00000138757homo_sapiensENSP0000035273887.344479.6681oryzias_latipesENSORLP0000003974982.54975.2941
ENSG00000138757homo_sapiensENSP0000035273887.966880.4979cyclopterus_lumpusENSCLMP0000500297383.300676.2279
ENSG00000138757homo_sapiensENSP0000035273884.439877.8008oreochromis_niloticusENSONIP0000002859276.647870.6215
ENSG00000138757homo_sapiensENSP0000035273886.514579.6681haplochromis_burtoniENSHBUP0000000594982.086675.5906
ENSG00000138757homo_sapiensENSP0000035273886.514579.6681astatotilapia_callipteraENSACLP0000003393282.086675.5906
ENSG00000138757homo_sapiensENSP0000035273889.211681.9502sparus_aurataENSSAUP0001003915284.645777.7559
ENSG00000138757homo_sapiensENSP0000035273886.72279.6681lates_calcariferENSLCAP0001000385584.274277.4194
ENSG00000138757homo_sapiensENSP0000035273891.493884.8548xenopus_tropicalisENSXETP0000000070391.115784.5041
ENSG00000138757homo_sapiensENSP0000035273896.680593.5685chrysemys_picta_belliiENSCPBP0000001850191.552188.6051
ENSG00000138757homo_sapiensENSP0000035273895.850692.1162sphenodon_punctatusENSSPUP0000001170495.850692.1162
ENSG00000138757homo_sapiensENSP0000035273896.88893.7759crocodylus_porosusENSCPRP0000501052881.076478.4722
ENSG00000138757homo_sapiensENSP0000035273880.705473.6515laticauda_laticaudataENSLLTP0000000430884.934577.5109
ENSG00000138757homo_sapiensENSP0000035273892.738686.722notechis_scutatusENSNSUP0000002488192.738686.722
ENSG00000138757homo_sapiensENSP0000035273892.738686.3071pseudonaja_textilisENSPTXP0000002124892.738686.3071
ENSG00000138757homo_sapiensENSP0000035273896.265693.361anas_platyrhynchos_platyrhynchosENSAPLP0000002473596.265693.361
ENSG00000138757homo_sapiensENSP0000035273896.47393.1535gallus_gallusENSGALP0001000351787.570684.5574
ENSG00000138757homo_sapiensENSP0000035273825.311223.6515meleagris_gallopavoENSMGAP0000000734754.95551.3514
ENSG00000138757homo_sapiensENSP0000035273896.47393.1535serinus_canariaENSSCAP0000000607196.47393.1535
ENSG00000138757homo_sapiensENSP0000035273895.850692.3237parus_majorENSPMJP0000000085796.049992.5156
ENSG00000138757homo_sapiensENSP0000035273894.605890.4564anolis_carolinensisENSACAP0000000870690.836786.8526
ENSG00000138757homo_sapiensENSP0000035273886.514579.6681neolamprologus_brichardiENSNBRP0000001536182.086675.5906
ENSG00000138757homo_sapiensENSP0000035273893.36186.9295naja_najaENSNNAP0000002185293.36186.9295
ENSG00000138757homo_sapiensENSP0000035273894.813390.4564podarcis_muralisENSPMRP0000002850994.813390.4564
ENSG00000138757homo_sapiensENSP0000035273896.47392.7386geospiza_fortisENSGFOP0000001564296.47392.7386
ENSG00000138757homo_sapiensENSP0000035273896.265692.9461taeniopygia_guttataENSTGUP0000000161796.265692.9461
ENSG00000138757homo_sapiensENSP0000035273877.800870.9544erpetoichthys_calabaricusENSECRP0000000431383.518976.1693
ENSG00000138757homo_sapiensENSP0000035273887.966880.9129kryptolebias_marmoratusENSKMAP0000000351583.629276.9231
ENSG00000138757homo_sapiensENSP0000035273895.228290.4564salvator_merianaeENSSMRP0000002172695.228290.4564
ENSG00000138757homo_sapiensENSP0000035273887.966880.083oryzias_javanicusENSOJAP0000000405982.974675.5382
ENSG00000138757homo_sapiensENSP0000035273881.742775.1037amphilophus_citrinellusENSACIP0000002383887.361480.2661
ENSG00000138757homo_sapiensENSP0000035273889.211681.5353dicentrarchus_labraxENSDLAP0000502866384.148776.908
ENSG00000138757homo_sapiensENSP0000035273888.381781.1203amphiprion_perculaENSAPEP0000001849883.693576.8173
ENSG00000138757homo_sapiensENSP0000035273887.551979.4606oryzias_sinensisENSOSIP0000002962366.772160.6013
ENSG00000138757homo_sapiensENSP0000035273896.47392.9461pelodiscus_sinensisENSPSIP0000000879995.09291.6155
ENSG00000138757homo_sapiensENSP0000035273896.47393.361gopherus_evgoodeiENSGEVP0000501294496.47393.361
ENSG00000138757homo_sapiensENSP0000035273889.626686.5145chelonoidis_abingdoniiENSCABP0000000434296.213892.8731
ENSG00000138757homo_sapiensENSP0000035273889.626682.1577seriola_dumeriliENSSDUP0000001099985.039477.9528
ENSG00000138757homo_sapiensENSP0000035273887.551979.8755cottoperca_gobioENSCGOP0000000190082.745175.4902
ENSG00000138757homo_sapiensENSP0000035273896.680593.7759struthio_camelus_australisENSSCUP0000002358496.680593.7759
ENSG00000138757homo_sapiensENSP0000035273896.265693.361anser_brachyrhynchusENSABRP0000000775296.265693.361
ENSG00000138757homo_sapiensENSP0000035273888.174379.6681gasterosteus_aculeatusENSGACP0000002291087.628979.1753
ENSG00000138757homo_sapiensENSP0000035273888.796780.7054cynoglossus_semilaevisENSCSEP0000001493988.065880.0412
ENSG00000138757homo_sapiensENSP0000035273887.551980.2905poecilia_formosaENSPFOP0000000477882.907776.0314
ENSG00000138757homo_sapiensENSP0000035273889.83481.7427myripristis_murdjanENSMMDP0000504402385.404377.712
ENSG00000138757homo_sapiensENSP0000035273889.004281.1203sander_luciopercaENSSLUP0000000982884.448876.9685
ENSG00000138757homo_sapiensENSP0000035273896.47393.361strigops_habroptilaENSSHBP0000501654196.47393.361
ENSG00000138757homo_sapiensENSP0000035273888.381781.1203amphiprion_ocellarisENSAOCP0000001863584.189777.2727
ENSG00000138757homo_sapiensENSP0000035273829.875527.8008amphiprion_ocellarisENSAOCP0000003168892.307785.8974
ENSG00000138757homo_sapiensENSP0000035273896.680593.5685terrapene_carolina_triunguisENSTMTP0000000906396.680593.5685
ENSG00000138757homo_sapiensENSP0000035273832.987630.2905hucho_huchoENSHHUP0000008118876.442370.1923
ENSG00000138757homo_sapiensENSP0000035273829.253127.1784hucho_huchoENSHHUP0000008119587.577681.3665
ENSG00000138757homo_sapiensENSP0000035273887.136980.083hucho_huchoENSHHUP0000004929281.553474.9515
ENSG00000138757homo_sapiensENSP0000035273889.419182.1577betta_splendensENSBSLP0000000018785.009978.1065
ENSG00000138757homo_sapiensENSP0000035273881.120373.444pygocentrus_nattereriENSPNAP0000001514077.120369.8225
ENSG00000138757homo_sapiensENSP0000035273889.419181.7427anabas_testudineusENSATEP0000005776884.675877.4067
ENSG00000138757homo_sapiensENSP0000035273855.186743.5685ciona_savignyiENSCSAVP0000001391857.575845.4545
ENSG00000138757homo_sapiensENSP0000035273835.062222.4066saccharomyces_cerevisiaeYNR051C32.815520.9709
ENSG00000138757homo_sapiensENSP0000035273889.626682.1577seriola_lalandi_dorsalisENSSLDP0000002944385.039477.9528
ENSG00000138757homo_sapiensENSP0000035273882.365175.3112labrus_bergyltaENSLBEP0000002150483.755376.5823
ENSG00000138757homo_sapiensENSP0000035273886.72279.6681pundamilia_nyerereiENSPNYP0000001428082.283575.5906
ENSG00000138757homo_sapiensENSP0000035273889.211681.5353mastacembelus_armatusENSMAMP0000004952084.812677.5148
ENSG00000138757homo_sapiensENSP0000035273888.381780.4979stegastes_partitusENSSPAP0000001294884.023776.5286
ENSG00000138757homo_sapiensENSP0000035273889.004281.5353acanthochromis_polyacanthusENSAPOP0000002076784.448877.3622
ENSG00000138757homo_sapiensENSP0000035273896.680593.7759aquila_chrysaetos_chrysaetosENSACCP0002000133096.680593.7759
ENSG00000138757homo_sapiensENSP0000035273887.551980.083nothobranchius_furzeriENSNFUP0001500935882.583275.5382
ENSG00000138757homo_sapiensENSP0000035273887.344480.4979cyprinodon_variegatusENSCVAP0000002583982.711276.2279
ENSG00000138757homo_sapiensENSP0000035273888.589281.7427denticeps_clupeoidesENSDCDP0000001514183.561677.1037
ENSG00000138757homo_sapiensENSP0000035273889.211681.9502larimichthys_croceaENSLCRP0000501881284.812677.9093
ENSG00000138757homo_sapiensENSP0000035273886.307178.4232takifugu_rubripesENSTRUP0000002881082.539775
ENSG00000138757homo_sapiensENSP0000035273895.643291.0788ficedula_albicollisENSFALP0000000854593.131388.6869
ENSG00000138757homo_sapiensENSP0000035273887.551978.8382hippocampus_comesENSHCOP0000001950683.234774.9507
ENSG00000138757homo_sapiensENSP0000035273883.402575.1037cyprinus_carpio_carpioENSCCRP0000016963479.289971.4004
ENSG00000138757homo_sapiensENSP0000035273896.265692.9461coturnix_japonicaENSCJPP0000501160496.265692.9461
ENSG00000138757homo_sapiensENSP0000035273887.551980.2905poecilia_latipinnaENSPLAP0000001924682.907776.0314
ENSG00000138757homo_sapiensENSP0000035273883.6175.1037sinocyclocheilus_grahamiENSSGRP0000003023772.612665.2252
ENSG00000138757homo_sapiensENSP0000035273886.514579.6681maylandia_zebraENSMZEP0000502603382.086675.5906
ENSG00000138757homo_sapiensENSP0000035273880.08370.1245tetraodon_nigroviridisENSTNIP0000001398080.249570.2703
ENSG00000138757homo_sapiensENSP0000035273886.929579.8755paramormyrops_kingsleyaeENSPKIP0000003483083.466176.6932
ENSG00000138757homo_sapiensENSP0000035273885.269777.8008paramormyrops_kingsleyaeENSPKIP0000003371881.547674.4048
ENSG00000138757homo_sapiensENSP0000035273888.796782.7801scleropages_formosusENSSFOP0001502129784.086478.389
ENSG00000138757homo_sapiensENSP0000035273885.892178.6307scleropages_formosusENSSFOP0001502782081.818274.9012
ENSG00000138757homo_sapiensENSP0000035273884.439879.2531leptobrachium_leishanenseENSLLEP0000001957183.744978.6008
ENSG00000138757homo_sapiensENSP0000035273888.589280.7054scophthalmus_maximusENSSMAP0000000968084.220976.7258
ENSG00000138757homo_sapiensENSP0000035273887.966880.083oryzias_melastigmaENSOMEP0000000384478.664271.6141

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003729enables mRNA binding1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005737located_in cytoplasm1NASHomo_sapiens(9606)Component
GO:0005829is_active_in cytosol3IBA,IDA,TASHomo_sapiens(9606)Component
GO:0007253involved_in cytoplasmic sequestering of NF-kappaB1NASHomo_sapiens(9606)Process
GO:0007265involved_in Ras protein signal transduction1NASHomo_sapiens(9606)Process
GO:0010494located_in cytoplasmic stress granule1IMPHomo_sapiens(9606)Component
GO:0030159enables signaling receptor complex adaptor activity1NASHomo_sapiens(9606)Function
GO:0034063involved_in stress granule assembly1IDAHomo_sapiens(9606)Process
GO:0045087involved_in innate immune response1IEAHomo_sapiens(9606)Process
GO:0051028involved_in mRNA transport1IEAHomo_sapiens(9606)Process
GO:0051260involved_in protein homooligomerization1IMPHomo_sapiens(9606)Process
GO:0062029involved_in positive regulation of stress granule assembly1IMPHomo_sapiens(9606)Process
GO:0140693enables molecular condensate scaffold activity1IDAHomo_sapiens(9606)Function
GO:1990904part_of ribonucleoprotein complex1IBAHomo_sapiens(9606)Component

Expression