Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Metabolic enzyme
Localizations N.A.
BulkPerturb-seq

Description

Ensembl ID ENSG00000137817 Gene ID 56965 Accession 26921
Symbol PARP6 Alias Full Name
Status Confidence Length 31819 bases Strand Minus strand
Position 15 : 72241181 - 72272999 RNA binding domain PARP
Summary

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000455815 PARP PF00644 1.5e-12 1
ENSP00000287196 PARP PF00644 1.8e-12 1
ENSP00000456348 PARP PF00644 1.8e-12 1
ENSP00000403265 PARP PF00644 6.9e-12 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
35836822 Suppression of Long Noncoding RNA SNHG1 Inhibits the Development of Hypopharyngeal Squamous Cell Carcinoma via Increasing PARP6 Expression. Qian Chen 2022-01-01 Evidence-based complementary and alternative medicine : eCAM

Transcripts

Name Transcript ID bp Protein Translation ID
PARP6-219 ENST00000569173 516 80aa ENSP00000456749
PARP6-220 ENST00000569795 2788 630aa ENSP00000456348
PARP6-201 ENST00000260376 2142 518aa ENSP00000260376
PARP6-223 ENST00000616176 2102 440aa ENSP00000484561
PARP6-203 ENST00000413097 2750 No protein -
PARP6-202 ENST00000287196 2625 630aa ENSP00000287196
PARP6-222 ENST00000569972 836 No protein -
PARP6-206 ENST00000564610 1876 451aa ENSP00000456468
PARP6-216 ENST00000567974 1950 564aa ENSP00000455815
PARP6-205 ENST00000544520 2341 No protein -
PARP6-207 ENST00000565443 2305 519aa ENSP00000456370
PARP6-211 ENST00000566991 3657 No protein -
PARP6-214 ENST00000567440 2271 251aa ENSP00000454298
PARP6-213 ENST00000567263 845 124aa ENSP00000457752
PARP6-209 ENST00000566831 718 No protein -
PARP6-204 ENST00000419739 1718 553aa ENSP00000403265
PARP6-212 ENST00000567042 601 17aa ENSP00000455637
PARP6-221 ENST00000569890 304 73aa ENSP00000455847
PARP6-217 ENST00000568213 616 No protein -
PARP6-208 ENST00000565999 740 76aa ENSP00000457134
PARP6-218 ENST00000568360 596 73aa ENSP00000457862
PARP6-210 ENST00000566844 829 26aa ENSP00000457187
PARP6-215 ENST00000567633 405 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
7609Kidney Diseases6.56056680034625E-917903292

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003950enables NAD+ ADP-ribosyltransferase activity1IBAHomo_sapiens(9606)Function
GO:0005635is_active_in nuclear envelope1IBAHomo_sapiens(9606)Component
GO:0016779enables nucleotidyltransferase activity1IEAHomo_sapiens(9606)Function
GO:0019900enables kinase binding1IBAHomo_sapiens(9606)Function
GO:0030968involved_in endoplasmic reticulum unfolded protein response1IBAHomo_sapiens(9606)Process
GO:0043539enables protein serine/threonine kinase activator activity1IBAHomo_sapiens(9606)Function
GO:0050775involved_in positive regulation of dendrite morphogenesis1IEAHomo_sapiens(9606)Process
GO:0070213involved_in protein auto-ADP-ribosylation1IDAHomo_sapiens(9606)Process
GO:0071782is_active_in endoplasmic reticulum tubular network1IBAHomo_sapiens(9606)Component
GO:0140803enables NAD+- protein-cysteine ADP-ribosyltransferase activity1IDAHomo_sapiens(9606)Function
GO:0140806enables NAD+- protein-aspartate ADP-ribosyltransferase activity1IDAHomo_sapiens(9606)Function

Expression