Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerCHIKVSARS-COV-OC43FlavivirusesHIVIAVRVSARS-COV-2DengueZika
Drug N.A.
Main interacting RNAs ncRNA
Moonlighting functions N.A.
Localizations Stress granucleP-bodyNucleoli
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000135829 Gene ID 1660 Accession 2750
Symbol DHX9 Alias LKP;RHA;DDX9;NDH2;NDHII Full Name DExH-box helicase 9
Status Confidence Length 48636 bases Strand Plus strand
Position 1 : 182839347 - 182887982 RNA binding domain DEAD , dsrm , HA2 , OB_NTP_bind
Summary This gene encodes a member of the DEAH-containing family of RNA helicases. The encoded protein is an enzyme that catalyzes the ATP-dependent unwinding of double-stranded RNA and DNA-RNA complexes. This protein localizes to both the nucleus and the cytoplasm and functions as a transcriptional regulator. This protein may also be involved in the expression and nuclear export of retroviral RNAs. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 11 and 13.[provided by RefSeq, Feb 2010]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000356520 DEAD PF00270 6.6e-06 1
ENSP00000356520 dsrm PF00035 1.8e-26 2
ENSP00000356520 dsrm PF00035 1.8e-26 3
ENSP00000356520 HA2 PF04408 2.2e-14 4
ENSP00000356520 OB_NTP_bind PF07717 1.5e-13 5

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
21957149 DHX9 pairs with IPS-1 to sense double-stranded RNA in myeloid dendritic cells. Zhiqiang Zhang 2011-11-01 Journal of immunology (Baltimore, Md. : 1950)
28588071 The RNA helicase DHX9 establishes nucleolar heterochromatin, and this activity is required for embryonic stem cell differentiation. Sergio Leone 2017-07-01 EMBO reports
30341290 DHX9 helicase promotes R-loop formation in cells with impaired RNA splicing. Prasun Chakraborty 2018-10-19 Nature communications
28221134 Human Nup98 regulates the localization and activity of DExH/D-box helicase DHX9. S Juliana Capitanio 2017-02-21 eLife
36402769 Mutant RIG-I enhances cancer-related inflammation through activation of circRIG-I signaling. Jia Song 2022-11-19 Nature communications
36897170 A novel circular RNA circRBMS3 regulates proliferation and metastasis of osteosarcoma by targeting miR-424-eIF4B/YRDC axis. Zhe Gong 2023-03-09 Aging
37065473 Regulation of ncRNAs involved with ferroptosis in various cancers. Chenxi Hu 2023-01-01 Frontiers in genetics
31866285 RNA-based therapeutics for colorectal cancer: Updates and future directions. Jingwen Liu 2020-02-01 Pharmacological research
28586325 Distinct mechanisms obviate the potentially toxic effects of inverted-repeat Alu elements on cellular RNA metabolism. A Reyad Elbarbary 2017-06-06 Nature structural & molecular biology
35410446 Long noncoding RNA SH3PXD2A-AS1 promotes NSCLC proliferation and accelerates cell cycle progression by interacting with DHX9. Yeqing Zhou 2022-04-11 Cell death discovery
36038948 CircRNA-CREIT inhibits stress granule assembly and overcomes doxorubicin resistance in TNBC by destabilizing PKR. Xiaolong Wang 2022-08-29 Journal of hematology & oncology
30865310 Lnc-UCID Promotes G1/S Transition and Hepatoma Growth by Preventing DHX9-Mediated CDK6 Down-regulation. Yun-Long Wang 2019-07-01 Hepatology (Baltimore, Md.)
34226554 DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination. Prasun Chakraborty 2021-07-05 Nature communications
24161410 Poxviruses and the evolution of host range and virulence. L Sherry Haller 2014-01-01 Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
33795683 A KRAS-responsive long non-coding RNA controls microRNA processing. Lei Shi 2021-04-01 Nature communications
33821441 Circular RNA circ-PTEN elevates PTEN inhibiting the proliferation of non-small cell lung cancer cells. Yuan Wang 2021-07-01 Human cell
29572294 Systematic characterization of pan-cancer mutation clusters. Marija Buljan 2018-03-23 Molecular systems biology

Transcripts

Name Transcript ID bp Protein Translation ID
DHX9-201 ENST00000367549 4493 1270aa ENSP00000356520
DHX9-206 ENST00000483416 814 No protein -
DHX9-205 ENST00000479271 316 No protein -
DHX9-204 ENST00000477802 456 No protein -
DHX9-208 ENST00000490519 438 No protein -
DHX9-203 ENST00000474446 848 No protein -
DHX9-207 ENST00000485081 2531 No protein -
DHX9-202 ENST00000473076 1378 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000135829homo_sapiensENSP0000026848231.866319.1524homo_sapiensENSP0000035652030.787418.5039
ENSG00000135829homo_sapiensENSP0000025163639.225724.1782homo_sapiensENSP0000035652042.283526.063
ENSG00000135829homo_sapiensENSP0000033190734.383220.385homo_sapiensENSP0000035652030.944918.3465
ENSG00000135829homo_sapiensENSP0000028469039.434721.9381homo_sapiensENSP0000035652023.070912.8346
ENSG00000135829homo_sapiensENSP0000022529642.008526.0255homo_sapiensENSP0000035652023.385814.4882
ENSG00000135829homo_sapiensENSP0000024781521.803110.0276homo_sapiensENSP0000035652018.66148.58268
ENSG00000135829homo_sapiensENSP0000038462139.051622.4547homo_sapiensENSP0000035652022.047212.6772
ENSG00000135829homo_sapiensENSP0000025201147.368428.734homo_sapiensENSP0000035652026.220515.9055
ENSG00000135829homo_sapiensENSP0000031113531.633518.9283homo_sapiensENSP0000035652028.818917.2441
ENSG00000135829homo_sapiensENSP0000040511140.40426.4791homo_sapiensENSP0000035652044.094528.8976
ENSG00000135829homo_sapiensENSP0000036562536.215222.0941homo_sapiensENSP0000035652029.68518.1102
ENSG00000135829homo_sapiensENSP0000041707851.785733.5317homo_sapiensENSP0000035652041.102426.6142
ENSG00000135829homo_sapiensENSP0000025124141.206724.5186homo_sapiensENSP0000035652025.275615.0394
ENSG00000135829homo_sapiensENSP0000016186332.517522.1678homo_sapiensENSP0000035652036.614224.9606
ENSG00000135829homo_sapiensENSP0000033674143.52224.4025homo_sapiensENSP0000035652027.244115.2756
ENSG00000135829homo_sapiensENSP0000040562037.855923.7018homo_sapiensENSP0000035652035.590522.2835
ENSG00000135829homo_sapiensENSP0000026241532.213118.6066homo_sapiensENSP0000035652030.944917.874
ENSG00000135829homo_sapiensENSP0000038730328.726517.5832homo_sapiensENSP0000035652031.259819.1339

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000135829homo_sapiensENSP0000035652099.842599.7638nomascus_leucogenysENSNLEP0000002188499.45199.3726
ENSG00000135829homo_sapiensENSP00000356520100100pan_paniscusENSPPAP00000014111100100
ENSG00000135829homo_sapiensENSP0000035652099.842599.8425pongo_abeliiENSPPYP0000000049099.921299.9212
ENSG00000135829homo_sapiensENSP00000356520100100pan_troglodytesENSPTRP00000002937100100
ENSG00000135829homo_sapiensENSP0000035652099.921399.9213gorilla_gorillaENSGGOP0000002697699.921399.9213
ENSG00000135829homo_sapiensENSP0000035652093.149688.8189ornithorhynchus_anatinusENSOANP0000004203786.921482.8802
ENSG00000135829homo_sapiensENSP0000035652093.62289.0551sarcophilus_harrisiiENSSHAP0000000986394.365189.7619
ENSG00000135829homo_sapiensENSP0000035652060.551257.7165notamacropus_eugeniiENSMEUP0000000136665.895562.8106
ENSG00000135829homo_sapiensENSP0000035652079.212677.4016choloepus_hoffmanniENSCHOP0000001130087.478385.4783
ENSG00000135829homo_sapiensENSP0000035652095.74893.4646dasypus_novemcinctusENSDNOP0000000310996.126593.834
ENSG00000135829homo_sapiensENSP0000035652070.787468.3465erinaceus_europaeusENSEEUP0000000447671.067268.6166
ENSG00000135829homo_sapiensENSP0000035652075.905572.7559echinops_telfairiENSETEP0000000790374.382771.2963
ENSG00000135829homo_sapiensENSP0000035652097.322896.5354callithrix_jacchusENSCJAP0000000903499.117998.316
ENSG00000135829homo_sapiensENSP0000035652099.606399.5276cercocebus_atysENSCATP0000000937999.215799.1373
ENSG00000135829homo_sapiensENSP0000035652099.68599.6063macaca_fascicularisENSMFAP0000004100999.294199.2157
ENSG00000135829homo_sapiensENSP0000035652099.68599.6063macaca_mulattaENSMMUP0000000745099.294199.2157
ENSG00000135829homo_sapiensENSP0000035652099.68599.6063macaca_nemestrinaENSMNEP0000003621399.294199.2157
ENSG00000135829homo_sapiensENSP0000035652099.606399.5276papio_anubisENSPANP0000001749999.215799.1373
ENSG00000135829homo_sapiensENSP0000035652099.606399.5276mandrillus_leucophaeusENSMLEP0000003159699.215799.1373
ENSG00000135829homo_sapiensENSP0000035652086.850485.0394tursiops_truncatusENSTTRP0000000725195.663593.6687
ENSG00000135829homo_sapiensENSP0000035652096.614294.5669vulpes_vulpesENSVVUP0000001207296.159994.1223
ENSG00000135829homo_sapiensENSP0000035652095.039491.5748mus_spretusMGP_SPRETEiJ_P002146787.14883.9711
ENSG00000135829homo_sapiensENSP0000035652097.086694.9606equus_asinusENSEASP0000505064696.02893.9252
ENSG00000135829homo_sapiensENSP0000035652094.25291.6535capra_hircusENSCHIP0000001977794.177891.5814
ENSG00000135829homo_sapiensENSP0000035652096.535494.0157loxodonta_africanaENSLAFP0000002830495.112592.6299
ENSG00000135829homo_sapiensENSP0000035652096.929194.8819panthera_leoENSPLOP0000001635096.473494.4357
ENSG00000135829homo_sapiensENSP0000035652096.771794.6457ailuropoda_melanoleucaENSAMEP0000002939795.940793.8329
ENSG00000135829homo_sapiensENSP0000035652096.299294.0945bos_indicus_hybridENSBIXP0000504414795.027292.8516
ENSG00000135829homo_sapiensENSP0000035652095.74893.4646oryctolagus_cuniculusENSOCUP0000002990993.682691.4484
ENSG00000135829homo_sapiensENSP0000035652096.850494.7244equus_caballusENSECAP0000001350197.079794.9487
ENSG00000135829homo_sapiensENSP0000035652096.692994.5669canis_lupus_familiarisENSCAFP0084500615896.238294.1223
ENSG00000135829homo_sapiensENSP0000035652096.771794.7244panthera_pardusENSPPRP0000001228196.847994.7991
ENSG00000135829homo_sapiensENSP0000035652093.070990.6299marmota_marmota_marmotaENSMMMP0000001714692.415989.9922
ENSG00000135829homo_sapiensENSP0000035652095.826893.4646balaenoptera_musculusENSBMSP0001000010296.894994.5064
ENSG00000135829homo_sapiensENSP0000035652094.330791.2598cavia_porcellusENSCPOP0000002916987.254284.4137
ENSG00000135829homo_sapiensENSP0000035652093.858391.8898felis_catusENSFCAP0000001614886.817284.9964
ENSG00000135829homo_sapiensENSP0000035652096.771794.7244ursus_americanusENSUAMP0000001594096.316694.279
ENSG00000135829homo_sapiensENSP0000035652093.464688.8189monodelphis_domesticaENSMODP0000000862794.281289.5949
ENSG00000135829homo_sapiensENSP0000035652095.984393.7008bison_bison_bisonENSBBBP0000002639796.059993.7746
ENSG00000135829homo_sapiensENSP0000035652095.905593.622monodon_monocerosENSMMNP0001501376197.206794.8923
ENSG00000135829homo_sapiensENSP0000035652096.456793.937sus_scrofaENSSSCP0000002938688.511686.1994
ENSG00000135829homo_sapiensENSP0000035652097.086694.7244microcebus_murinusENSMICP0000000755697.470495.0988
ENSG00000135829homo_sapiensENSP0000035652094.960691.811octodon_degusENSODEP0000001717786.513683.6442
ENSG00000135829homo_sapiensENSP0000035652094.173290.1575jaculus_jaculusENSJJAP0000000213487.554983.8214
ENSG00000135829homo_sapiensENSP0000035652096.299293.937ovis_aries_rambouilletENSOARP0002000463994.879892.5524
ENSG00000135829homo_sapiensENSP0000035652096.850494.8031ursus_maritimusENSUMAP0000002253396.39594.3574
ENSG00000135829homo_sapiensENSP0000035652077.086674.9606ochotona_princepsENSOPRP0000001473084.982682.6389
ENSG00000135829homo_sapiensENSP0000035652095.905593.622delphinapterus_leucasENSDLEP0000002869397.206794.8923
ENSG00000135829homo_sapiensENSP0000035652095.74893.3858physeter_catodonENSPCTP0000500324896.584694.2017
ENSG00000135829homo_sapiensENSP0000035652095.118191.6535mus_caroliMGP_CAROLIEiJ_P002040587.726984.5316
ENSG00000135829homo_sapiensENSP0000035652095.118191.6535mus_musculusENSMUSP0000003813587.283284.104
ENSG00000135829homo_sapiensENSP0000035652095.905592.9921dipodomys_ordiiENSDORP0000001186288.581885.8909
ENSG00000135829homo_sapiensENSP0000035652091.417389.4488mustela_putorius_furoENSMPUP0000001145396.7594.6667
ENSG00000135829homo_sapiensENSP0000035652099.055198.4252aotus_nancymaaeENSANAP0000002520999.055198.4252
ENSG00000135829homo_sapiensENSP0000035652094.960693.5433saimiri_boliviensis_boliviensisENSSBOP0000001923396.24994.8124
ENSG00000135829homo_sapiensENSP0000035652081.181179.1339vicugna_pacosENSVPAP0000000753781.309279.2587
ENSG00000135829homo_sapiensENSP0000035652087.716587.2441chlorocebus_sabaeusENSCSAP0000000873098.934398.4014
ENSG00000135829homo_sapiensENSP0000035652068.425266.6142tupaia_belangeriENSTBEP0000001220868.7566.9304
ENSG00000135829homo_sapiensENSP0000035652094.881991.4173mesocricetus_auratusENSMAUP0000002322886.940883.7662
ENSG00000135829homo_sapiensENSP0000035652095.905593.7008phocoena_sinusENSPSNP0000000373397.206794.9721
ENSG00000135829homo_sapiensENSP0000035652093.070990.2362camelus_dromedariusENSCDRP0000502049689.545586.8182
ENSG00000135829homo_sapiensENSP0000035652097.559195.2756carlito_syrichtaENSTSYP0000001687597.405795.1258
ENSG00000135829homo_sapiensENSP0000035652096.771794.7244panthera_tigris_altaicaENSPTIP0000002518696.847994.7991
ENSG00000135829homo_sapiensENSP0000035652095.118191.6535rattus_norvegicusENSRNOP0000009095686.781683.6207
ENSG00000135829homo_sapiensENSP0000035652097.401695.3543prolemur_simusENSPSMP0000000281596.716294.6833
ENSG00000135829homo_sapiensENSP0000035652095.118191.7323microtus_ochrogasterENSMOCP0000002232887.220284.1155
ENSG00000135829homo_sapiensENSP0000035652081.181178.2677sorex_araneusENSSARP0000000359488.879385.6897
ENSG00000135829homo_sapiensENSP0000035652094.488290.9449peromyscus_maniculatus_bairdiiENSPEMP0000000152787.082783.8171
ENSG00000135829homo_sapiensENSP0000035652096.299294.0945bos_mutusENSBMUP0000003626195.027292.8516
ENSG00000135829homo_sapiensENSP0000035652095.039491.5748mus_spicilegusENSMSIP0000001481087.21184.0318
ENSG00000135829homo_sapiensENSP0000035652090.551287.4016cricetulus_griseus_chok1gshdENSCGRP0000101512293.57290.3173
ENSG00000135829homo_sapiensENSP0000035652095.826893.3858pteropus_vampyrusENSPVAP0000000079195.977993.5331
ENSG00000135829homo_sapiensENSP0000035652095.669392.7559myotis_lucifugusENSMLUP0000001020395.59492.6829
ENSG00000135829homo_sapiensENSP0000035652093.228388.2677vombatus_ursinusENSVURP0001001306494.117689.1097
ENSG00000135829homo_sapiensENSP0000035652094.25290rhinolophus_ferrumequinumENSRFEP0001003188895.302691.0032
ENSG00000135829homo_sapiensENSP0000035652096.929194.7244neovison_visonENSNVIP0000001906295.872393.6916
ENSG00000135829homo_sapiensENSP0000035652096.299294.0945bos_taurusENSBTAP0000002640995.027292.8516
ENSG00000135829homo_sapiensENSP0000035652095.039491.8898heterocephalus_glaber_femaleENSHGLP0000003844887.845784.9345
ENSG00000135829homo_sapiensENSP0000035652099.606399.4488rhinopithecus_bietiENSRBIP0000003509799.215799.0588
ENSG00000135829homo_sapiensENSP0000035652096.692994.5669canis_lupus_dingoENSCAFP0002001872996.238294.1223
ENSG00000135829homo_sapiensENSP0000035652091.732389.685sciurus_vulgarisENSSVLP0000501548195.805993.6678
ENSG00000135829homo_sapiensENSP0000035652093.543388.5039phascolarctos_cinereusENSPCIP0000000447794.435689.3482
ENSG00000135829homo_sapiensENSP0000035652078.661475.9055procavia_capensisENSPCAP0000001040878.9176.1453
ENSG00000135829homo_sapiensENSP0000035652034.173232.9921nannospalax_galiliENSNGAP0000001179697.309493.9462
ENSG00000135829homo_sapiensENSP0000035652092.283590.2362bos_grunniensENSBGRP0000001776394.592492.4939
ENSG00000135829homo_sapiensENSP0000035652095.196992.2835chinchilla_lanigeraENSCLAP0000001554087.672284.9891
ENSG00000135829homo_sapiensENSP0000035652096.614294.3307cervus_hanglu_yarkandensisENSCHYP0000002542495.412193.1571
ENSG00000135829homo_sapiensENSP0000035652096.299293.622catagonus_wagneriENSCWAP0000002554788.816386.3471
ENSG00000135829homo_sapiensENSP0000035652096.535493.7795ictidomys_tridecemlineatusENSSTOP0000001458892.319389.6837
ENSG00000135829homo_sapiensENSP0000035652096.850493.622otolemur_garnettiiENSOGAP0000000234796.622293.4014
ENSG00000135829homo_sapiensENSP0000035652088.582787.7165cebus_imitatorENSCCAP0000000974699.031798.0634
ENSG00000135829homo_sapiensENSP0000035652096.771794.0945urocitellus_parryiiENSUPAP0001000670592.545289.9849
ENSG00000135829homo_sapiensENSP0000035652096.37894.0945moschus_moschiferusENSMMSP0000001856495.178892.9238
ENSG00000135829homo_sapiensENSP0000035652099.606399.4488rhinopithecus_roxellanaENSRROP0000004340999.215799.0588
ENSG00000135829homo_sapiensENSP0000035652032.992131.1024mus_pahariMGP_PahariEiJ_P007568493.73688.3669
ENSG00000135829homo_sapiensENSP0000035652097.007994.8819propithecus_coquereliENSPCOP0000001287397.622895.4834
ENSG00000135829homo_sapiensENSP0000035652062.519743.0709caenorhabditis_elegansT07D4.3a.161.0342.0446
ENSG00000135829homo_sapiensENSP0000035652068.267750.3937drosophila_melanogasterFBpp008536767.053449.4973
ENSG00000135829homo_sapiensENSP0000035652035.039427.0079ciona_intestinalisENSCINP0000001597474.915857.7441
ENSG00000135829homo_sapiensENSP0000035652023.307117.874ciona_intestinalisENSCINP0000001597171.670754.9637
ENSG00000135829homo_sapiensENSP0000035652066.614254.7244eptatretus_burgeriENSEBUP0000002587077.543563.703
ENSG00000135829homo_sapiensENSP0000035652088.110278.1102callorhinchus_miliiENSCMIP0000004314579.587570.5548
ENSG00000135829homo_sapiensENSP0000035652071.496160.315latimeria_chalumnaeENSLACP0000002021572.698261.3291
ENSG00000135829homo_sapiensENSP0000035652086.771777.7165lepisosteus_oculatusENSLOCP0000000252986.908577.8391
ENSG00000135829homo_sapiensENSP0000035652084.488274.8819clupea_harengusENSCHAP0000005986184.621575
ENSG00000135829homo_sapiensENSP0000035652085.590676.7717danio_rerioENSDARP0000011850985.523276.7113
ENSG00000135829homo_sapiensENSP0000035652084.173274.5669carassius_auratusENSCARP0000002327485.043875.3381
ENSG00000135829homo_sapiensENSP0000035652081.889873.0709carassius_auratusENSCARP0000003096184.415675.3247
ENSG00000135829homo_sapiensENSP000003565206.220475.19685astyanax_mexicanusENSAMXP0000004116795.180779.5181
ENSG00000135829homo_sapiensENSP0000035652029.133925.1181astyanax_mexicanusENSAMXP0000002151483.710472.1719
ENSG00000135829homo_sapiensENSP0000035652084.094574.4882ictalurus_punctatusENSIPUP0000002470282.983773.5043
ENSG00000135829homo_sapiensENSP0000035652085.74876.063esox_luciusENSELUP0000003257685.344875.7053
ENSG00000135829homo_sapiensENSP0000035652082.204773.1496electrophorus_electricusENSEEEP0000000916785.573876.1475
ENSG00000135829homo_sapiensENSP0000035652052.913444.9606oncorhynchus_kisutchENSOKIP0000507350180.190968.1384
ENSG00000135829homo_sapiensENSP0000035652085.590676.4567oncorhynchus_kisutchENSOKIP0000507402181.729373.0075
ENSG00000135829homo_sapiensENSP0000035652085.826876.6142oncorhynchus_mykissENSOMYP0000005830582.202173.3786
ENSG00000135829homo_sapiensENSP0000035652024.960620.9449oncorhynchus_mykissENSOMYP0000010761575.296963.1829
ENSG00000135829homo_sapiensENSP0000035652085.669376.6929salmo_salarENSSSAP0000011483081.315472.7952
ENSG00000135829homo_sapiensENSP0000035652084.724475.1969salmo_truttaENSSTUP0000004357183.865974.4349
ENSG00000135829homo_sapiensENSP0000035652083.307174.0157gadus_morhuaENSGMOP0000002839482.980473.7255
ENSG00000135829homo_sapiensENSP0000035652024.960620.9449fundulus_heteroclitusENSFHEP0000000961581.074268.0307
ENSG00000135829homo_sapiensENSP0000035652082.677273.4646poecilia_reticulataENSPREP0000002854686.348776.727
ENSG00000135829homo_sapiensENSP0000035652084.015774.4882xiphophorus_maculatusENSXMAP0000001136085.63475.923
ENSG00000135829homo_sapiensENSP0000035652085.196975.1969oryzias_latipesENSORLP0000000934984.333674.4349
ENSG00000135829homo_sapiensENSP0000035652083.464673.7008cyclopterus_lumpusENSCLMP0000502630584.260774.4038
ENSG00000135829homo_sapiensENSP0000035652085.511876.1417oreochromis_niloticusENSONIP0000000036884.316875.0776
ENSG00000135829homo_sapiensENSP0000035652085.039475.8268haplochromis_burtoniENSHBUP0000002336584.972575.7671
ENSG00000135829homo_sapiensENSP0000035652085.118176.063astatotilapia_callipteraENSACLP0000003287985.051176.0032
ENSG00000135829homo_sapiensENSP0000035652085.275675.5118sparus_aurataENSSAUP0001000784282.420172.9833
ENSG00000135829homo_sapiensENSP0000035652085.590676.2205lates_calcariferENSLCAP0001000922582.787573.7243
ENSG00000135829homo_sapiensENSP0000035652088.346578.8976xenopus_tropicalisENSXETP0000002739089.260179.7136
ENSG00000135829homo_sapiensENSP0000035652091.889885.1181chrysemys_picta_belliiENSCPBP0000002199792.39985.5899
ENSG00000135829homo_sapiensENSP0000035652090.236284.1732sphenodon_punctatusENSSPUP0000000509490.378584.306
ENSG00000135829homo_sapiensENSP0000035652090.236284.0157crocodylus_porosusENSCPRP0000501988391.533585.2236
ENSG00000135829homo_sapiensENSP0000035652042.204736.9291laticauda_laticaudataENSLLTP0000001207982.208671.9325
ENSG00000135829homo_sapiensENSP0000035652087.637880.315notechis_scutatusENSNSUP0000001980889.469581.9936
ENSG00000135829homo_sapiensENSP0000035652088.18981.0236pseudonaja_textilisENSPTXP0000000502489.682.32
ENSG00000135829homo_sapiensENSP0000035652086.37877.3228serinus_canariaENSSCAP0000001541789.259679.9024
ENSG00000135829homo_sapiensENSP0000035652085.039476.7717parus_majorENSPMJP0000002631585.987377.6274
ENSG00000135829homo_sapiensENSP0000035652088.818981.4961anolis_carolinensisENSACAP0000000497589.452882.0777
ENSG00000135829homo_sapiensENSP0000035652024.645721.3386neolamprologus_brichardiENSNBRP0000003207078.841368.262
ENSG00000135829homo_sapiensENSP0000035652088.18980.8661naja_najaENSNNAP0000002307089.456982.0288
ENSG00000135829homo_sapiensENSP0000035652087.87480.8661podarcis_muralisENSPMRP0000000120989.782882.6227
ENSG00000135829homo_sapiensENSP0000035652020.629917.7165geospiza_fortisENSGFOP0000001151080.864269.4444
ENSG00000135829homo_sapiensENSP0000035652062.677257.2441geospiza_fortisENSGFOP0000001177788.346380.6881
ENSG00000135829homo_sapiensENSP0000035652086.535477.0866taeniopygia_guttataENSTGUP0000000415888.62978.9516
ENSG00000135829homo_sapiensENSP0000035652086.771777.1654erpetoichthys_calabaricusENSECRP0000001740485.294175.8514
ENSG00000135829homo_sapiensENSP0000035652018.110215.8268kryptolebias_marmoratusENSKMAP0000002406582.437372.043
ENSG00000135829homo_sapiensENSP0000035652088.503981.8898salvator_merianaeENSSMRP0000001569185.280778.9074
ENSG00000135829homo_sapiensENSP0000035652086.06376.063oryzias_javanicusENSOJAP0000002592084.663174.8257
ENSG00000135829homo_sapiensENSP0000035652084.724475.748amphilophus_citrinellusENSACIP0000002122084.724475.748
ENSG00000135829homo_sapiensENSP0000035652083.307174.3307dicentrarchus_labraxENSDLAP0000504513086.226676.9356
ENSG00000135829homo_sapiensENSP0000035652085.669376.4567amphiprion_perculaENSAPEP0000000889682.486773.6164
ENSG00000135829homo_sapiensENSP0000035652085.196975.0394oryzias_sinensisENSOSIP0000004365082.848472.9709
ENSG00000135829homo_sapiensENSP0000035652091.338684.9606pelodiscus_sinensisENSPSIP0000000675891.554985.1618
ENSG00000135829homo_sapiensENSP0000035652091.889885.4331gopherus_evgoodeiENSGEVP0000501890492.39985.9066
ENSG00000135829homo_sapiensENSP0000035652089.055182.5984chelonoidis_abingdoniiENSCABP0000002588093.163186.4086
ENSG00000135829homo_sapiensENSP0000035652080.472471.1811seriola_dumeriliENSSDUP0000002393286.757276.7402
ENSG00000135829homo_sapiensENSP0000035652085.984379.4488struthio_camelus_australisENSSCUP0000000660891.075984.1535
ENSG00000135829homo_sapiensENSP0000035652076.456767.4803cynoglossus_semilaevisENSCSEP0000002763587.635477.3466
ENSG00000135829homo_sapiensENSP000003565204.488193.85827poecilia_formosaENSPFOP0000003068263.333354.4444
ENSG00000135829homo_sapiensENSP0000035652080.708772.3622myripristis_murdjanENSMMDP0000503919083.947675.2662
ENSG00000135829homo_sapiensENSP0000035652084.409474.5669sander_luciopercaENSSLUP0000003438284.409474.5669
ENSG00000135829homo_sapiensENSP0000035652087.165478.5039strigops_habroptilaENSSHBP0000501842189.130480.2738
ENSG00000135829homo_sapiensENSP0000035652073.858365.5906amphiprion_ocellarisENSAOCP0000000696987.9178.0694
ENSG00000135829homo_sapiensENSP0000035652091.653584.9606terrapene_carolina_triunguisENSTMTP0000003130692.89786.1133
ENSG00000135829homo_sapiensENSP0000035652091.889885.1181terrapene_carolina_triunguisENSTMTP0000002159992.91486.0669
ENSG00000135829homo_sapiensENSP0000035652085.118176.2992hucho_huchoENSHHUP0000002264682.456173.913
ENSG00000135829homo_sapiensENSP0000035652055.275649.685hucho_huchoENSHHUP0000007488183.472175.0297
ENSG00000135829homo_sapiensENSP0000035652084.173274.8031betta_splendensENSBSLP0000004350685.179375.6972
ENSG00000135829homo_sapiensENSP0000035652085.275676.1417pygocentrus_nattereriENSPNAP0000003300485.680476.5032
ENSG00000135829homo_sapiensENSP0000035652085.039475.9843anabas_testudineusENSATEP0000004353685.646376.5266
ENSG00000135829homo_sapiensENSP0000035652071.81157.0079ciona_savignyiENSCSAVP0000000253174.086158.814
ENSG00000135829homo_sapiensENSP0000035652079.527670.4724seriola_lalandi_dorsalisENSSLDP0000000507088.132678.0977
ENSG00000135829homo_sapiensENSP0000035652014.25212.4409labrus_bergyltaENSLBEP0000002019879.039368.9956
ENSG00000135829homo_sapiensENSP0000035652084.173275.4331pundamilia_nyerereiENSPNYP0000001124184.976276.1526
ENSG00000135829homo_sapiensENSP0000035652084.488275.2756mastacembelus_armatusENSMAMP0000006465685.36276.0541
ENSG00000135829homo_sapiensENSP0000035652084.25275.3543stegastes_partitusENSSPAP0000001285084.318475.4137
ENSG00000135829homo_sapiensENSP0000035652084.881975.748oncorhynchus_tshawytschaENSOTSP0000502217083.114974.1712
ENSG00000135829homo_sapiensENSP0000035652028.740224.8032acanthochromis_polyacanthusENSAPOP0000000037883.143571.754
ENSG00000135829homo_sapiensENSP0000035652086.929178.7402aquila_chrysaetos_chrysaetosENSACCP0002001203588.888980.5153
ENSG00000135829homo_sapiensENSP0000035652082.204772.3622nothobranchius_furzeriENSNFUP0001502432679.150969.674
ENSG00000135829homo_sapiensENSP0000035652081.732373.1496cyprinodon_variegatusENSCVAP0000002500885.361876.398
ENSG00000135829homo_sapiensENSP0000035652083.700873.937denticeps_clupeoidesENSDCDP0000000306084.633874.7611
ENSG00000135829homo_sapiensENSP0000035652085.433175.9055larimichthys_croceaENSLCRP0000504048983.978374.613
ENSG00000135829homo_sapiensENSP0000035652083.070972.7559takifugu_rubripesENSTRUP0000008831583.070972.7559
ENSG00000135829homo_sapiensENSP0000035652083.858375.5118ficedula_albicollisENSFALP0000000311687.510378.8003
ENSG00000135829homo_sapiensENSP0000035652082.755972.2835hippocampus_comesENSHCOP0000001034482.951972.4546
ENSG00000135829homo_sapiensENSP0000035652084.25274.4094cyprinus_carpio_carpioENSCCRP0000017964185.463375.4792
ENSG00000135829homo_sapiensENSP0000035652083.149673.937poecilia_latipinnaENSPLAP0000000063986.063676.5281
ENSG00000135829homo_sapiensENSP000003565205.354334.25197sinocyclocheilus_grahamiENSSGRP0000006692880.952464.2857
ENSG00000135829homo_sapiensENSP0000035652085.118176.063maylandia_zebraENSMZEP0000501887885.051176.0032
ENSG00000135829homo_sapiensENSP0000035652068.818960.4724tetraodon_nigroviridisENSTNIP0000000536787.051876.494
ENSG00000135829homo_sapiensENSP0000035652080.629971.1811tetraodon_nigroviridisENSTNIP0000000700386.050475.9664
ENSG00000135829homo_sapiensENSP0000035652085.354374.8819paramormyrops_kingsleyaeENSPKIP0000002284884.292473.9502
ENSG00000135829homo_sapiensENSP0000035652086.299275.0394scleropages_formosusENSSFOP0001502709486.915175.5749
ENSG00000135829homo_sapiensENSP0000035652088.110278.8189leptobrachium_leishanenseENSLLEP0000002957588.040978.7569
ENSG00000135829homo_sapiensENSP0000035652081.259871.1024scophthalmus_maximusENSSMAP0000005656883.902473.4146
ENSG00000135829homo_sapiensENSP0000035652082.204772.2835oryzias_melastigmaENSOMEP0000000158087.952877.3378

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000380involved_in alternative mRNA splicing, via spliceosome1IMPHomo_sapiens(9606)Process
GO:0000978enables RNA polymerase II cis-regulatory region sequence-specific DNA binding1IDAHomo_sapiens(9606)Function
GO:0000993enables RNA polymerase II complex binding1IDAHomo_sapiens(9606)Function
GO:0001069enables regulatory region RNA binding1IDAHomo_sapiens(9606)Function
GO:0001649involved_in osteoblast differentiation1HDAHomo_sapiens(9606)Process
GO:0003677enables DNA binding1ISSHomo_sapiens(9606)Function
GO:0003678enables DNA helicase activity1IMPHomo_sapiens(9606)Function
GO:0003688enables DNA replication origin binding1IDAHomo_sapiens(9606)Function
GO:0003690enables double-stranded DNA binding1IDAHomo_sapiens(9606)Function
GO:0003697enables single-stranded DNA binding1IDAHomo_sapiens(9606)Function
GO:0003712enables transcription coregulator activity1IMPHomo_sapiens(9606)Function
GO:0003713enables transcription coactivator activity1IMPHomo_sapiens(9606)Function
GO:0003723enables RNA binding3HDA,IBA,IDAHomo_sapiens(9606)Function
GO:0003724enables RNA helicase activity3IBA,IDA,ISSHomo_sapiens(9606)Function
GO:0003725enables double-stranded RNA binding1IDAHomo_sapiens(9606)Function
GO:0003727enables single-stranded RNA binding1IDAHomo_sapiens(9606)Function
GO:0003729enables mRNA binding2IDA,IMPHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IDAHomo_sapiens(9606)Function
GO:0005622is_active_in intracellular anatomical structure1IBAHomo_sapiens(9606)Component
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005726located_in perichromatin fibrils1IDAHomo_sapiens(9606)Component
GO:0005730is_active_in nucleolus2IBA,IDAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005813located_in centrosome1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0005844part_of polysome1IDAHomo_sapiens(9606)Component
GO:0006260involved_in DNA replication1IEAHomo_sapiens(9606)Process
GO:0006353involved_in DNA-templated transcription termination1IEAHomo_sapiens(9606)Process
GO:0006357involved_in regulation of transcription by RNA polymerase II1IMPHomo_sapiens(9606)Process
GO:0006954involved_in inflammatory response1IEAHomo_sapiens(9606)Process
GO:0010501involved_in RNA secondary structure unwinding1IDAHomo_sapiens(9606)Process
GO:0015629located_in actin cytoskeleton1IDAHomo_sapiens(9606)Component
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016442part_of RISC complex1IDAHomo_sapiens(9606)Component
GO:0016604located_in nuclear body1IDAHomo_sapiens(9606)Component
GO:0016887enables ATP hydrolysis activity2IBA,IMPHomo_sapiens(9606)Function
GO:0017111enables ribonucleoside triphosphate phosphatase activity1ISSHomo_sapiens(9606)Function
GO:0031490enables chromatin DNA binding1IDAHomo_sapiens(9606)Function
GO:0032508involved_in DNA duplex unwinding3IDA,IMP,ISSHomo_sapiens(9606)Process
GO:0032727involved_in positive regulation of interferon-alpha production1IMPHomo_sapiens(9606)Process
GO:0032728involved_in positive regulation of interferon-beta production1IMPHomo_sapiens(9606)Process
GO:0032741involved_in positive regulation of interleukin-18 production1ISSHomo_sapiens(9606)Process
GO:0032755involved_in positive regulation of interleukin-6 production1IMPHomo_sapiens(9606)Process
GO:0032760involved_in positive regulation of tumor necrosis factor production1IMPHomo_sapiens(9606)Process
GO:0032991part_of protein-containing complex1IDAHomo_sapiens(9606)Component
GO:0033679enables 3-5 DNA/RNA helicase activity1IDAHomo_sapiens(9606)Function
GO:0034458enables 3-5 RNA helicase activity1IDAHomo_sapiens(9606)Function
GO:0035195involved_in miRNA-mediated gene silencing1IMPHomo_sapiens(9606)Process
GO:0035197enables siRNA binding1IDAHomo_sapiens(9606)Function
GO:0035613enables RNA stem-loop binding1IDAHomo_sapiens(9606)Function
GO:0036464located_in cytoplasmic ribonucleoprotein granule1IDAHomo_sapiens(9606)Component
GO:0039695involved_in DNA-templated viral transcription1IDAHomo_sapiens(9606)Process
GO:0042788located_in polysomal ribosome1IDAHomo_sapiens(9606)Component
GO:0043138enables 3-5 DNA helicase activity3IBA,IDA,ISSHomo_sapiens(9606)Function
GO:0044806involved_in G-quadruplex DNA unwinding1IDAHomo_sapiens(9606)Process
GO:0045087involved_in innate immune response1IEAHomo_sapiens(9606)Process
GO:0045089involved_in positive regulation of innate immune response1ISSHomo_sapiens(9606)Process
GO:0045142enables triplex DNA binding1IDAHomo_sapiens(9606)Function
GO:0045739involved_in positive regulation of DNA repair1IMPHomo_sapiens(9606)Process
GO:0045740involved_in positive regulation of DNA replication1IMPHomo_sapiens(9606)Process
GO:0045944involved_in positive regulation of transcription by RNA polymerase II2IBA,IMPHomo_sapiens(9606)Process
GO:0046833involved_in positive regulation of RNA export from nucleus1IDAHomo_sapiens(9606)Process
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function
GO:0047429enables nucleoside triphosphate diphosphatase activity1IDAHomo_sapiens(9606)Function
GO:0048146involved_in positive regulation of fibroblast proliferation1IMPHomo_sapiens(9606)Process
GO:0048511involved_in rhythmic process1IEAHomo_sapiens(9606)Process
GO:0050434involved_in positive regulation of viral transcription1IDAHomo_sapiens(9606)Process
GO:0050684involved_in regulation of mRNA processing2IBA,IDAHomo_sapiens(9606)Process
GO:0050691involved_in regulation of defense response to virus by host1ISSHomo_sapiens(9606)Process
GO:0050729involved_in positive regulation of inflammatory response1ISSHomo_sapiens(9606)Process
GO:0051028involved_in mRNA transport1IEAHomo_sapiens(9606)Process
GO:0051092involved_in positive regulation of NF-kappaB transcription factor activity1IMPHomo_sapiens(9606)Process
GO:0060760involved_in positive regulation of response to cytokine stimulus1IMPHomo_sapiens(9606)Process
GO:0061629enables RNA polymerase II-specific DNA-binding transcription factor binding1IPIHomo_sapiens(9606)Function
GO:0061676enables importin-alpha family protein binding1IDAHomo_sapiens(9606)Function
GO:0065003involved_in protein-containing complex assembly1IDAHomo_sapiens(9606)Process
GO:0070063enables RNA polymerase binding1IDAHomo_sapiens(9606)Function
GO:0070269involved_in pyroptosis1ISSHomo_sapiens(9606)Process
GO:0070578part_of RISC-loading complex1IMPHomo_sapiens(9606)Component
GO:0070922involved_in RISC complex assembly1IMPHomo_sapiens(9606)Process
GO:0070934involved_in CRD-mediated mRNA stabilization2IDA,IMPHomo_sapiens(9606)Process
GO:0070937part_of CRD-mediated mRNA stability complex2IDA,IPIHomo_sapiens(9606)Component
GO:0071356involved_in cellular response to tumor necrosis factor1IMPHomo_sapiens(9606)Process
GO:0071360involved_in cellular response to exogenous dsRNA1IMPHomo_sapiens(9606)Process
GO:0097165located_in nuclear stress granule2IDA,IMPHomo_sapiens(9606)Component
GO:1900152involved_in negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay1IDAHomo_sapiens(9606)Process
GO:1903608involved_in protein localization to cytoplasmic stress granule1IMPHomo_sapiens(9606)Process
GO:1904973involved_in positive regulation of viral translation1IMPHomo_sapiens(9606)Process
GO:1905172enables RISC complex binding1IDAHomo_sapiens(9606)Function
GO:1905538enables polysome binding1IDAHomo_sapiens(9606)Function
GO:1905698involved_in positive regulation of polysome binding1IMPHomo_sapiens(9606)Process
GO:1990518enables single-stranded 3-5 DNA helicase activity1IDAHomo_sapiens(9606)Function
GO:1990825enables sequence-specific mRNA binding1IDAHomo_sapiens(9606)Function
GO:1990841enables promoter-specific chromatin binding1IMPHomo_sapiens(9606)Function
GO:1990904part_of ribonucleoprotein complex3IBA,IDA,IMPHomo_sapiens(9606)Component
GO:2000373involved_in positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity1IMPHomo_sapiens(9606)Process
GO:2000765involved_in regulation of cytoplasmic translation1IDAHomo_sapiens(9606)Process
GO:2000767involved_in positive regulation of cytoplasmic translation2IDA,IMPHomo_sapiens(9606)Process

Expression