Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions Transmemebrane
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000135314 Gene ID 80759 Accession 21366
Symbol KHDC1 Alias NDG1;C6orf147;C6orf148;bA257K9.4;Em:AC019205.8 Full Name KH domain containing 1
Status Confidence Length 68902 bases Strand Minus strand
Position 6 : 73241314 - 73310215 RNA binding domain MOEP19
Summary Predicted to enable identical protein binding activity and poly(U) RNA binding activity. Predicted to be involved in activation of cysteine-type endopeptidase activity involved in apoptotic process. Predicted to be integral component of membrane. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000359411 MOEP19 PF16005 7.2e-28 1
ENSP00000406966 MOEP19 PF16005 9.4e-28 1
ENSP00000257765 MOEP19 PF16005 3.9e-27 1
ENSP00000479158 MOEP19 PF16005 3.9e-27 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
40144Platelet Function Tests3.5700000E-006-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000135314homo_sapiensENSP0000035941591.406284.375homo_sapiensENSP0000025776571.341565.8537
ENSG00000135314homo_sapiensENSP0000035939645.689723.2759homo_sapiensENSP0000025776532.317116.4634

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000135314homo_sapiensENSP0000025776599.390299.3902nomascus_leucogenysENSNLEP0000003107264.682564.6825
ENSG00000135314homo_sapiensENSP0000025776510099.3902pan_paniscusENSPPAP0000004185369.491569.0678
ENSG00000135314homo_sapiensENSP0000025776598.170798.1707pongo_abeliiENSPPYP0000002591998.170798.1707
ENSG00000135314homo_sapiensENSP00000257765100100pan_troglodytesENSPTRP0000003134569.491569.4915
ENSG00000135314homo_sapiensENSP00000257765100100pan_troglodytesENSPTRP00000064712100100
ENSG00000135314homo_sapiensENSP00000257765100100gorilla_gorillaENSGGOP0000003722069.198369.1983
ENSG00000135314homo_sapiensENSP0000025776549.390239.6341dasypus_novemcinctusENSDNOP0000003342055.10244.2177
ENSG00000135314homo_sapiensENSP0000025776595.121992.6829callithrix_jacchusENSCJAP0000004910895.121992.6829
ENSG00000135314homo_sapiensENSP0000025776599.390298.1707cercocebus_atysENSCATP0000001879599.390298.1707
ENSG00000135314homo_sapiensENSP0000025776510098.1707macaca_fascicularisENSMFAP0000006059447.813446.9388
ENSG00000135314homo_sapiensENSP0000025776510098.1707macaca_mulattaENSMMUP0000007135810098.1707
ENSG00000135314homo_sapiensENSP0000025776510098.1707macaca_nemestrinaENSMNEP0000002302269.491568.2203
ENSG00000135314homo_sapiensENSP0000025776599.390298.1707papio_anubisENSPANP0000005681046.306845.7386
ENSG00000135314homo_sapiensENSP0000025776599.390298.1707mandrillus_leucophaeusENSMLEP0000002516799.390298.1707
ENSG00000135314homo_sapiensENSP0000025776556.707340.8537loxodonta_africanaENSLAFP0000001760165.49347.1831
ENSG00000135314homo_sapiensENSP0000025776556.097646.9512oryctolagus_cuniculusENSOCUP0000004057149.197941.1765
ENSG00000135314homo_sapiensENSP0000025776551.219540.8537oryctolagus_cuniculusENSOCUP0000001693054.193643.2258
ENSG00000135314homo_sapiensENSP0000025776548.780538.4146oryctolagus_cuniculusENSOCUP0000000161066.115752.0661
ENSG00000135314homo_sapiensENSP0000025776557.317148.7805oryctolagus_cuniculusENSOCUP0000001661174.015762.9921
ENSG00000135314homo_sapiensENSP0000025776551.829342.6829oryctolagus_cuniculusENSOCUP0000003760049.132940.4624
ENSG00000135314homo_sapiensENSP0000025776551.829342.6829canis_lupus_familiarisENSCAFP0084501652770.247957.8512
ENSG00000135314homo_sapiensENSP0000025776555.487848.7805marmota_marmota_marmotaENSMMMP0000000317972.222263.4921
ENSG00000135314homo_sapiensENSP0000025776582.317171.9512microcebus_murinusENSMICP0000004154845.762740
ENSG00000135314homo_sapiensENSP0000025776573.780565.8537microcebus_murinusENSMICP0000004746356.018550
ENSG00000135314homo_sapiensENSP0000025776565.853758.5366microcebus_murinusENSMICP0000004491584.37575
ENSG00000135314homo_sapiensENSP0000025776554.87837.1951mus_caroliMGP_CAROLIEiJ_P001688554.216936.747
ENSG00000135314homo_sapiensENSP0000025776554.87837.1951mus_caroliMGP_CAROLIEiJ_P001688654.216936.747
ENSG00000135314homo_sapiensENSP0000025776556.707339.0244mus_musculusENSMUSP0000006879256.024138.5542
ENSG00000135314homo_sapiensENSP0000025776548.780537.1951mus_musculusENSMUSP0000012027563.492148.4127
ENSG00000135314homo_sapiensENSP0000025776556.097638.4146mus_musculusENSMUSP0000008574955.421737.9518
ENSG00000135314homo_sapiensENSP0000025776593.292787.8049aotus_nancymaaeENSANAP0000004189793.292787.8049
ENSG00000135314homo_sapiensENSP0000025776589.634183.5366aotus_nancymaaeENSANAP0000003491091.87585.625
ENSG00000135314homo_sapiensENSP0000025776595.731792.6829aotus_nancymaaeENSANAP0000002535295.731792.6829
ENSG00000135314homo_sapiensENSP0000025776596.341592.0732saimiri_boliviensis_boliviensisENSSBOP0000003225996.341592.0732
ENSG00000135314homo_sapiensENSP0000025776589.024481.7073saimiri_boliviensis_boliviensisENSSBOP0000002665991.823984.2767
ENSG00000135314homo_sapiensENSP0000025776598.780596.9512chlorocebus_sabaeusENSCSAP0000001006098.780596.9512
ENSG00000135314homo_sapiensENSP0000025776548.170739.0244camelus_dromedariusENSCDRP0000500225965.289352.8926
ENSG00000135314homo_sapiensENSP0000025776556.707343.2927rattus_norvegicusENSRNOP0000006540365.49350
ENSG00000135314homo_sapiensENSP0000025776553.658540.2439rattus_norvegicusENSRNOP0000009315549.438237.0787
ENSG00000135314homo_sapiensENSP0000025776553.658540.2439rattus_norvegicusENSRNOP0000007463363.309447.482
ENSG00000135314homo_sapiensENSP0000025776556.097642.0732rattus_norvegicusENSRNOP0000003978455.757641.8182
ENSG00000135314homo_sapiensENSP0000025776584.756178.0488prolemur_simusENSPSMP0000000552085.802579.0123
ENSG00000135314homo_sapiensENSP0000025776584.146377.439prolemur_simusENSPSMP0000000559384.146377.439
ENSG00000135314homo_sapiensENSP0000025776549.390237.1951mus_spicilegusENSMSIP0000002365064.285748.4127
ENSG00000135314homo_sapiensENSP000002577655041.4634neovison_visonENSNVIP0000001949265.079453.9683
ENSG00000135314homo_sapiensENSP0000025776554.268338.4146heterocephalus_glaber_femaleENSHGLP0000003509757.419440.6452
ENSG00000135314homo_sapiensENSP0000025776551.829337.1951heterocephalus_glaber_femaleENSHGLP0000003982262.043844.5255
ENSG00000135314homo_sapiensENSP0000025776599.390298.1707rhinopithecus_bietiENSRBIP0000003903669.067868.2203
ENSG00000135314homo_sapiensENSP0000025776560.975652.439sciurus_vulgarisENSSVLP0000502856178.740267.7165
ENSG00000135314homo_sapiensENSP0000025776573.170763.4146sciurus_vulgarisENSSVLP0000501120376.923166.6667
ENSG00000135314homo_sapiensENSP0000025776543.292737.8049ictidomys_tridecemlineatusENSSTOP0000002748275.531965.9574
ENSG00000135314homo_sapiensENSP0000025776596.341593.2927cebus_imitatorENSCCAP0000001746496.341593.2927
ENSG00000135314homo_sapiensENSP0000025776589.634182.3171cebus_imitatorENSCCAP0000002332191.87584.375
ENSG00000135314homo_sapiensENSP0000025776551.219540.8537urocitellus_parryiiENSUPAP0001000852965.62552.3438
ENSG00000135314homo_sapiensENSP0000025776598.780597.561rhinopithecus_roxellanaENSRROP0000002358068.644167.7966
ENSG00000135314homo_sapiensENSP0000025776582.317176.8293propithecus_coquereliENSPCOP0000002296182.317176.8293

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding1IBAHomo_sapiens(9606)Function
GO:0005737is_active_in cytoplasm1IBAHomo_sapiens(9606)Component
GO:0006919involved_in activation of cysteine-type endopeptidase activity involved in apoptotic process1IBAHomo_sapiens(9606)Process
GO:0016020located_in membrane1IEAHomo_sapiens(9606)Component

Expression