RBPWorld - a comprehensive database of RNA Binding Proteins

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Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	Stress granule or P-bodyFibrillar center
BulkPerturb-seq

Description

Ensembl ID	ENSG00000134909	Gene ID	9743	Accession	17399
Symbol	ARHGAP32	Alias	GRIT;RICS;GC-GAP;PX-RICS;p250GAP;p200RhoGAP	Full Name	Rho GTPase activating protein 32
Status	Confidence	Length	314265 bases	Strand	Minus strand
Position	11 : 128965060 - 129279324	RNA binding domain	N.A.
Summary	RICS is a neuron-associated GTPase-activating protein that may regulate dendritic spine morphology and strength by modulating Rho GTPase (see RHOA; MIM 165390) activity (Okabe et al., 2003 [PubMed 12531901]).[supplied by OMIM, Mar 2008]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
ARHGAP32-201	ENST00000310343	10111	2087aa	ENSP00000310561
ARHGAP32-209	ENST00000682385	10280	2101aa	ENSP00000507720
ARHGAP32-205	ENST00000526162	6868	No protein	-
ARHGAP32-202	ENST00000392657	6556	1738aa	ENSP00000376425
ARHGAP32-203	ENST00000524655	8194	946aa	ENSP00000432468
ARHGAP32-206	ENST00000527272	5289	1738aa	ENSP00000432862
ARHGAP32-208	ENST00000534357	401	No protein	-
ARHGAP32-207	ENST00000533509	1064	No protein	-
ARHGAP32-204	ENST00000525234	719	178aa	ENSP00000432303

Gene Model

Click here to download ENSG00000134909's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
3723	Cholesterol, LDL	2.2153669208801E-5	17903299
3726	Cholesterol, LDL	4.56204927790026E-5	17903299
4438	Cholesterol, LDL	8.28509725157495E-5	17903299
21670	Social Responsibility	3.317e-005	-
49965	Child Development Disorders, Pervasive	3.7184000E-005	-
49969	Child Development Disorders, Pervasive	5.0729000E-005	-
49998	Child Development Disorders, Pervasive	6.0662000E-005	-

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000134909's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000139	located_in Golgi membrane	1	IEA	Homo_sapiens(9606)	Component
GO:0001650	is_active_in fibrillar center	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005096	enables GTPase activator activity	2	IBA,TAS	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005654	is_active_in nucleoplasm	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005789	located_in endoplasmic reticulum membrane	1	IEA	Homo_sapiens(9606)	Component
GO:0005794	is_active_in Golgi apparatus	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	TAS	Homo_sapiens(9606)	Component
GO:0005938	is_active_in cell cortex	1	IBA	Homo_sapiens(9606)	Component
GO:0007264	involved_in small GTPase mediated signal transduction	1	IBA	Homo_sapiens(9606)	Process
GO:0010008	located_in endosome membrane	1	IEA	Homo_sapiens(9606)	Component
GO:0014069	located_in postsynaptic density	1	ISS	Homo_sapiens(9606)	Component
GO:0015629	is_active_in actin cytoskeleton	1	IBA	Homo_sapiens(9606)	Component
GO:0043197	located_in dendritic spine	1	IEA	Homo_sapiens(9606)	Component
GO:0051056	involved_in regulation of small GTPase mediated signal transduction	1	TAS	Homo_sapiens(9606)	Process
GO:1901981	enables phosphatidylinositol phosphate binding	1	IEA	Homo_sapiens(9606)	Function

Expression