RBP Type
Canonical_RBPs
Diseases
N.A.
Drug
N.A.
Main interacting RNAs
N.A.
Moonlighting functions
TF
Localizations
N.A.
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000130818 Gene ID
79088 Accession
20725
Symbol
ZNF426
Alias
K-RBP
Full Name
zinc finger protein 426
Status
Confidence
Length
15423 bases
Strand
Minus strand
Position
19 : 9523223 - 9538645
RNA binding domain
zf-met
Summary
Kaposi's sarcoma-associated herpesvirus (KSHV) can be reactivated from latency by the viral protein RTA. The protein encoded by this gene is a zinc finger transcriptional repressor that interacts with RTA to modulate RTA-mediated reactivation of KSHV. While the encoded protein can repress KSHV reactivation, RTA can induce degradation of this protein through the ubiquitin-proteasome pathway to overcome the repression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000468100
zf-met
PF12874 5.9e-06
1
ENSP00000253115
zf-met
PF12874 1.4e-05
1
ENSP00000439017
zf-met
PF12874 1.4e-05
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
Name
Transcript ID
bp
Protein
Translation ID
ZNF426-201
ENST00000253115
7104
554aa
ENSP00000253115
ZNF426-202
ENST00000535489
2375
554aa
ENSP00000439017
ZNF426-204
ENST00000593003
2402
516aa
ENSP00000468100
ZNF426-203
ENST00000589289
919
118aa
ENSP00000466469
ZNF426-205
ENST00000635810
582
47aa
ENSP00000490091
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
47586 Intelligence Tests 3.4837300E-005 - 47587 Intelligence Tests 3.4837300E-005 - 47613 Intelligence Tests 3.4837300E-005 - 48196 Child Development Disorders, Pervasive 4.1482000E-005 - 48223 Child Development Disorders, Pervasive 4.1482000E-005 -
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000130818 homo_sapiens ENSP00000493097 40.8867 29.064 homo_sapiens ENSP00000253115 14.9819 10.6498 ENSG00000130818 homo_sapiens ENSP00000247930 23.4657 16.4862 homo_sapiens ENSP00000253115 35.1986 24.7292 ENSG00000130818 homo_sapiens ENSP00000196489 36.7003 26.0943 homo_sapiens ENSP00000253115 39.3502 27.9783 ENSG00000130818 homo_sapiens ENSP00000320096 34.9845 24.4582 homo_sapiens ENSP00000253115 20.3971 14.2599 ENSG00000130818 homo_sapiens ENSP00000319305 40.0756 30.6238 homo_sapiens ENSP00000253115 38.2671 29.2419 ENSG00000130818 homo_sapiens ENSP00000326240 30.3279 20.8197 homo_sapiens ENSP00000253115 33.3935 22.9242 ENSG00000130818 homo_sapiens ENSP00000396857 35.4128 24.2202 homo_sapiens ENSP00000253115 34.8375 23.8267 ENSG00000130818 homo_sapiens ENSP00000228437 15.4806 9.48814 homo_sapiens ENSP00000253115 22.3827 13.7184 ENSG00000130818 homo_sapiens ENSP00000394380 47.3118 37.9032 homo_sapiens ENSP00000253115 31.769 25.4513 ENSG00000130818 homo_sapiens ENSP00000472024 38.8693 26.5018 homo_sapiens ENSP00000253115 39.7112 27.0758 ENSG00000130818 homo_sapiens ENSP00000366080 25 17.7239 homo_sapiens ENSP00000253115 24.1877 17.148 ENSG00000130818 homo_sapiens ENSP00000369777 35 24.8148 homo_sapiens ENSP00000253115 34.1155 24.1877 ENSG00000130818 homo_sapiens ENSP00000483662 36.6102 27.2881 homo_sapiens ENSP00000253115 38.9892 29.0614 ENSG00000130818 homo_sapiens ENSP00000396894 39.3321 29.8701 homo_sapiens ENSP00000253115 38.2671 29.0614 ENSG00000130818 homo_sapiens ENSP00000311319 36.5217 25.3913 homo_sapiens ENSP00000253115 37.9061 26.3538 ENSG00000130818 homo_sapiens ENSP00000345479 36.5217 25.7391 homo_sapiens ENSP00000253115 37.9061 26.7148 ENSG00000130818 homo_sapiens ENSP00000346348 42.236 30.4348 homo_sapiens ENSP00000253115 36.8231 26.5343 ENSG00000130818 homo_sapiens ENSP00000354414 48.3731 38.8286 homo_sapiens ENSP00000253115 40.2527 32.3105 ENSG00000130818 homo_sapiens ENSP00000395007 19.697 12.1212 homo_sapiens ENSP00000253115 23.4657 14.4404 ENSG00000130818 homo_sapiens ENSP00000389841 43.9623 32.4528 homo_sapiens ENSP00000253115 42.0578 31.0469 ENSG00000130818 homo_sapiens ENSP00000312352 7.97439 4.59837 homo_sapiens ENSP00000253115 24.7292 14.2599 ENSG00000130818 homo_sapiens ENSP00000337008 10.1733 6.25471 homo_sapiens ENSP00000253115 24.3682 14.9819 ENSG00000130818 homo_sapiens ENSP00000452877 10.5762 6.86661 homo_sapiens ENSP00000253115 24.1877 15.704 ENSG00000130818 homo_sapiens ENSP00000278314 36.6337 26.5677 homo_sapiens ENSP00000253115 40.0722 29.0614 ENSG00000130818 homo_sapiens ENSP00000351482 49.3261 35.0404 homo_sapiens ENSP00000253115 33.0325 23.4657 ENSG00000130818 homo_sapiens ENSP00000395524 31.4324 23.0769 homo_sapiens ENSP00000253115 42.7798 31.4079 ENSG00000130818 homo_sapiens ENSP00000300850 11.7904 7.42358 homo_sapiens ENSP00000253115 38.9892 24.5487 ENSG00000130818 homo_sapiens ENSP00000336620 11.5602 6.79062 homo_sapiens ENSP00000253115 25.8123 15.1625 ENSG00000130818 homo_sapiens ENSP00000507588 28.9552 20.597 homo_sapiens ENSP00000253115 35.0181 24.9097 ENSG00000130818 homo_sapiens ENSP00000500993 6.88195 4.39386 homo_sapiens ENSP00000253115 23.4657 14.9819 ENSG00000130818 homo_sapiens ENSP00000420418 25.5452 16.6667 homo_sapiens ENSP00000253115 29.6029 19.3141 ENSG00000130818 homo_sapiens ENSP00000338290 25.1758 15.7525 homo_sapiens ENSP00000253115 32.3105 20.2166 ENSG00000130818 homo_sapiens ENSP00000344162 39.4444 32.037 homo_sapiens ENSP00000253115 38.4477 31.2274 ENSG00000130818 homo_sapiens ENSP00000299687 7.11744 4.31495 homo_sapiens ENSP00000253115 28.8809 17.509 ENSG00000130818 homo_sapiens ENSP00000401947 37.3444 26.971 homo_sapiens ENSP00000253115 32.491 23.4657 ENSG00000130818 homo_sapiens ENSP00000375822 37.4745 27.0876 homo_sapiens ENSP00000253115 33.213 24.0072 ENSG00000130818 homo_sapiens ENSP00000364895 26.1519 17.8082 homo_sapiens ENSP00000253115 37.9061 25.8123 ENSG00000130818 homo_sapiens ENSP00000379169 30.749 22.339 homo_sapiens ENSP00000253115 42.2383 30.6859 ENSG00000130818 homo_sapiens ENSP00000356375 19.802 11.5512 homo_sapiens ENSP00000253115 32.491 18.9531 ENSG00000130818 homo_sapiens ENSP00000302455 34.488 23.9458 homo_sapiens ENSP00000253115 41.3357 28.7004 ENSG00000130818 homo_sapiens ENSP00000390179 47.2906 35.3038 homo_sapiens ENSP00000253115 51.9856 38.8087 ENSG00000130818 homo_sapiens ENSP00000282282 40.5473 29.8507 homo_sapiens ENSP00000253115 29.4224 21.6607 ENSG00000130818 homo_sapiens ENSP00000309606 24.5833 16.25 homo_sapiens ENSP00000253115 31.9495 21.1191 ENSG00000130818 homo_sapiens ENSP00000304769 30.2521 18.8235 homo_sapiens ENSP00000253115 32.491 20.2166 ENSG00000130818 homo_sapiens ENSP00000270014 35.6877 25.8364 homo_sapiens ENSP00000253115 34.657 25.0903 ENSG00000130818 homo_sapiens ENSP00000409318 39.2405 29.1139 homo_sapiens ENSP00000253115 33.574 24.9097 ENSG00000130818 homo_sapiens ENSP00000321812 39.5753 27.7992 homo_sapiens ENSP00000253115 37.0036 25.9928 ENSG00000130818 homo_sapiens ENSP00000348162 10.0735 6.50577 homo_sapiens ENSP00000253115 17.3285 11.1913 ENSG00000130818 homo_sapiens ENSP00000299237 30.2405 21.4777 homo_sapiens ENSP00000253115 31.769 22.5632 ENSG00000130818 homo_sapiens ENSP00000355459 52.1851 41.1311 homo_sapiens ENSP00000253115 36.6426 28.8809 ENSG00000130818 homo_sapiens ENSP00000292530 32.1805 23.0075 homo_sapiens ENSP00000253115 38.6282 27.6173
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000130818 homo_sapiens ENSP00000253115 98.556 97.6534 nomascus_leucogenys ENSNLEP00000035739 98.556 97.6534 ENSG00000130818 homo_sapiens ENSP00000253115 99.278 99.0975 pan_paniscus ENSPPAP00000008135 99.278 99.0975 ENSG00000130818 homo_sapiens ENSP00000253115 98.7365 97.6534 pongo_abelii ENSPPYP00000010688 98.7365 97.6534 ENSG00000130818 homo_sapiens ENSP00000253115 99.278 99.0975 pan_troglodytes ENSPTRP00000079960 99.278 99.0975 ENSG00000130818 homo_sapiens ENSP00000253115 99.0975 98.556 gorilla_gorilla ENSGGOP00000029101 99.0975 98.556 ENSG00000130818 homo_sapiens ENSP00000253115 94.4043 91.6968 callithrix_jacchus ENSCJAP00000079639 93.7276 91.0394 ENSG00000130818 homo_sapiens ENSP00000253115 92.4188 91.3357 cercocebus_atys ENSCATP00000037031 97.7099 96.5649 ENSG00000130818 homo_sapiens ENSP00000253115 97.1119 95.6679 macaca_fascicularis ENSMFAP00000015448 96.0714 94.6429 ENSG00000130818 homo_sapiens ENSP00000253115 96.9314 95.4874 macaca_mulatta ENSMMUP00000052923 97.4592 96.0073 ENSG00000130818 homo_sapiens ENSP00000253115 97.1119 95.6679 macaca_nemestrina ENSMNEP00000030922 97.6407 96.1888 ENSG00000130818 homo_sapiens ENSP00000253115 97.2924 95.6679 papio_anubis ENSPANP00000009092 97.8221 96.1888 ENSG00000130818 homo_sapiens ENSP00000253115 92.4188 91.3357 mandrillus_leucophaeus ENSMLEP00000017004 97.7099 96.5649 ENSG00000130818 homo_sapiens ENSP00000253115 83.213 73.8267 mus_spretus MGP_SPRETEiJ_P0090414 81.7376 72.5177 ENSG00000130818 homo_sapiens ENSP00000253115 13.7184 11.5523 equus_asinus ENSEASP00005056639 67.2566 56.6372 ENSG00000130818 homo_sapiens ENSP00000253115 14.2599 11.9134 ailuropoda_melanoleuca ENSAMEP00000001272 68.1034 56.8966 ENSG00000130818 homo_sapiens ENSP00000253115 14.8014 11.3718 bos_indicus_hybrid ENSBIXP00005022409 61.6541 47.3684 ENSG00000130818 homo_sapiens ENSP00000253115 84.296 76.8953 oryctolagus_cuniculus ENSOCUP00000002821 90.3288 82.3985 ENSG00000130818 homo_sapiens ENSP00000253115 13.7184 11.7329 equus_caballus ENSECAP00000049581 67.2566 57.5221 ENSG00000130818 homo_sapiens ENSP00000253115 9.9278 9.02527 balaenoptera_musculus ENSBMSP00010017585 64.7059 58.8235 ENSG00000130818 homo_sapiens ENSP00000253115 14.8014 11.5523 bison_bison_bison ENSBBBP00000021215 61.6541 48.1203 ENSG00000130818 homo_sapiens ENSP00000253115 80.3249 69.3141 jaculus_jaculus ENSJJAP00000021447 81.2044 70.073 ENSG00000130818 homo_sapiens ENSP00000253115 83.574 73.8267 mus_caroli MGP_CAROLIEiJ_P0086864 81.8021 72.2615 ENSG00000130818 homo_sapiens ENSP00000253115 83.213 73.2852 mus_musculus ENSMUSP00000127045 81.7376 71.9858 ENSG00000130818 homo_sapiens ENSP00000253115 91.1552 88.0866 aotus_nancymaae ENSANAP00000004628 96.7433 93.4866 ENSG00000130818 homo_sapiens ENSP00000253115 94.9458 91.8773 saimiri_boliviensis_boliviensis ENSSBOP00000034869 96.5138 93.3945 ENSG00000130818 homo_sapiens ENSP00000253115 77.6173 76.8953 chlorocebus_sabaeus ENSCSAP00000003935 97.7273 96.8182 ENSG00000130818 homo_sapiens ENSP00000253115 82.6715 73.2852 mesocricetus_auratus ENSMAUP00000008850 82.2262 72.8905 ENSG00000130818 homo_sapiens ENSP00000253115 10.2888 9.38628 phocoena_sinus ENSPSNP00000021752 67.0588 61.1765 ENSG00000130818 homo_sapiens ENSP00000253115 15.5235 12.9964 camelus_dromedarius ENSCDRP00005005640 72.8814 61.0169 ENSG00000130818 homo_sapiens ENSP00000253115 92.9603 87.3646 carlito_syrichta ENSTSYP00000013957 92.9603 87.3646 ENSG00000130818 homo_sapiens ENSP00000253115 82.6715 73.4657 rattus_norvegicus ENSRNOP00000038875 81.7857 72.6786 ENSG00000130818 homo_sapiens ENSP00000253115 91.6968 86.4621 prolemur_simus ENSPSMP00000030103 89.2794 84.1828 ENSG00000130818 homo_sapiens ENSP00000253115 83.3935 72.9242 microtus_ochrogaster ENSMOCP00000022657 83.3935 72.9242 ENSG00000130818 homo_sapiens ENSP00000253115 75.9928 67.148 peromyscus_maniculatus_bairdii ENSPEMP00000011320 86.8041 76.701 ENSG00000130818 homo_sapiens ENSP00000253115 15.5235 12.2744 bos_mutus ENSBMUP00000008357 65.1515 51.5152 ENSG00000130818 homo_sapiens ENSP00000253115 83.213 73.6462 mus_spicilegus ENSMSIP00000021283 81.7376 72.3404 ENSG00000130818 homo_sapiens ENSP00000253115 82.13 72.0217 cricetulus_griseus_chok1gshd ENSCGRP00001006116 80.1056 70.2465 ENSG00000130818 homo_sapiens ENSP00000253115 15.8845 12.2744 bos_taurus ENSBTAP00000059569 66.1654 51.1278 ENSG00000130818 homo_sapiens ENSP00000253115 85.3791 77.2563 heterocephalus_glaber_female ENSHGLP00000013789 89.414 80.9074 ENSG00000130818 homo_sapiens ENSP00000253115 97.6534 96.2094 rhinopithecus_bieti ENSRBIP00000029400 98.1851 96.7332 ENSG00000130818 homo_sapiens ENSP00000253115 11.9134 9.56679 sciurus_vulgaris ENSSVLP00005021268 73.3333 58.8889 ENSG00000130818 homo_sapiens ENSP00000253115 11.7329 9.56679 sciurus_vulgaris ENSSVLP00005021354 60.1852 49.0741 ENSG00000130818 homo_sapiens ENSP00000253115 85.9206 77.4368 nannospalax_galili ENSNGAP00000005798 86.7031 78.1421 ENSG00000130818 homo_sapiens ENSP00000253115 13.8989 12.0939 bos_grunniens ENSBGRP00000002375 71.9626 62.6168 ENSG00000130818 homo_sapiens ENSP00000253115 10.1083 9.02527 cervus_hanglu_yarkandensis ENSCHYP00000001245 69.1358 61.7284 ENSG00000130818 homo_sapiens ENSP00000253115 94.9458 92.0578 cebus_imitator ENSCCAP00000034932 95.2899 92.3913 ENSG00000130818 homo_sapiens ENSP00000253115 15.704 11.9134 moschus_moschiferus ENSMMSP00000005729 60 45.5172 ENSG00000130818 homo_sapiens ENSP00000253115 10.4693 9.38628 moschus_moschiferus ENSMMSP00000005756 71.6049 64.1975 ENSG00000130818 homo_sapiens ENSP00000253115 97.4729 96.0289 rhinopithecus_roxellana ENSRROP00000000887 98.0036 96.5517 ENSG00000130818 homo_sapiens ENSP00000253115 83.935 73.8267 mus_pahari MGP_PahariEiJ_P0022511 77.2425 67.9402 ENSG00000130818 homo_sapiens ENSP00000253115 92.9603 86.8231 propithecus_coquereli ENSPCOP00000020312 92.9603 86.8231
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000978 enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 1 IBA Homo_sapiens(9606) Function GO:0000981 enables DNA-binding transcription factor activity, RNA polymerase II-specific 1 IBA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005634 is_active_in nucleus 1 IBA Homo_sapiens(9606) Component GO:0006357 involved_in regulation of transcription by RNA polymerase II 1 IBA Homo_sapiens(9606) Process GO:0046872 enables metal ion binding 1 IEA Homo_sapiens(9606) Function
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.
