Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerDengue
Drug Drug
Main interacting RNAs ncRNA
Moonlighting functions TF
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000130816 Gene ID 1786 Accession 2976
Symbol DNMT1 Alias AIM;DNMT;MCMT;CXXC9;HSN1E;ADCADN;m.HsaI Full Name DNA methyltransferase 1
Status Confidence Length 97941 bases Strand Minus strand
Position 19 : 10133346 - 10231286 RNA binding domain N.A.
Summary This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
36574982 DNMT1 inhibition by pUG-fold quadruplex RNA. I Linnea Jansson-Fritzberg 2023-03-01 RNA (New York, N.Y.)
19388845 DNA Methyltransferase protein synthesis is reduced in CXXC finger protein 1-deficient embryonic stem cells. S Jill Butler 2009-05-01 DNA and cell biology
21507353 Dnmt1 structure and function. M Željko Svedružić 2011-01-01 Progress in molecular biology and translational science
25990724 Small RNA-mediated DNA (cytosine-5) methyltransferase 1 inhibition leads to aberrant DNA methylation. Guoqiang Zhang 2015-07-13 Nucleic acids research
19048127 A method for purification, identification and validation of DNMT1 mRNA binding proteins. Alexander Unterberger 2008-01-01 Biological procedures online
31698782 Emerging Roles of Long Non-Coding RNAs as Drivers of Brain Evolution. Geraldine Zimmer-Bensch 2019-11-06 Cells
34908111 Circular RNAs in stem cells: from basic research to clinical implications. Hui-Juan Lu 2022-01-28 Bioscience reports
31485661 Circular RNAs: A novel target among non‑coding RNAs with potential roles in malignant tumors (Review). Weisong Zhao 2019-10-01 Molecular medicine reports
25863539 The long non-coding RNA HNF1A-AS1 regulates proliferation and metastasis in lung adenocarcinoma. Ying Wu 2015-04-20 Oncotarget
32718982 Functional annotation of human long noncoding RNAs via molecular phenotyping. A Jordan Ramilowski 2020-07-01 Genome research
29416775 The DNA methyl-transferase protein DNMT1 enhances tumor-promoting properties of breast stromal fibroblasts. A Layla Al-Kharashi 2018-01-05 Oncotarget
36725842 LncRNA TINCR impairs the efficacy of immunotherapy against breast cancer by recruiting DNMT1 and downregulating MiR-199a-5p via the STAT1-TINCR-USP20-PD-L1 axis. Qin Wang 2023-02-01 Cell death & disease
30108179 Human proteins that interact with RNA/DNA hybrids. X Isabel Wang 2018-09-01 Genome research

Transcripts

Name Transcript ID bp Protein Translation ID
DNMT1-207 ENST00000586667 3259 No protein -
DNMT1-206 ENST00000586588 3094 No protein -
DNMT1-227 ENST00000592705 5215 89aa ENSP00000466657
DNMT1-202 ENST00000359526 5274 1632aa ENSP00000352516
DNMT1-201 ENST00000340748 5408 1616aa ENSP00000345739
DNMT1-224 ENST00000591798 521 No protein -
DNMT1-243 ENST00000678107 2204 No protein -
DNMT1-219 ENST00000589351 4395 No protein -
DNMT1-249 ENST00000678957 2873 No protein -
DNMT1-250 ENST00000679100 3348 No protein -
DNMT1-246 ENST00000678694 4482 No protein -
DNMT1-240 ENST00000677783 6469 No protein -
DNMT1-232 ENST00000676868 5845 No protein -
DNMT1-242 ENST00000678024 6142 No protein -
DNMT1-229 ENST00000676604 4821 No protein -
DNMT1-237 ENST00000677616 5101 1150aa ENSP00000503055
DNMT1-239 ENST00000677685 4974 184aa ENSP00000503407
DNMT1-233 ENST00000677013 5175 89aa ENSP00000503135
DNMT1-236 ENST00000677250 5127 263aa ENSP00000502894
DNMT1-231 ENST00000676820 6055 No protein -
DNMT1-238 ENST00000677634 5165 1114aa ENSP00000504246
DNMT1-251 ENST00000679103 5126 1577aa ENSP00000503151
DNMT1-234 ENST00000677038 1756 No protein -
DNMT1-245 ENST00000678647 3302 No protein -
DNMT1-248 ENST00000678851 3143 No protein -
DNMT1-230 ENST00000676610 7157 1613aa ENSP00000504236
DNMT1-214 ENST00000588913 1775 389aa ENSP00000467125
DNMT1-247 ENST00000678804 5728 1658aa ENSP00000503853
DNMT1-252 ENST00000679313 5122 1580aa ENSP00000504512
DNMT1-235 ENST00000677135 653 No protein -
DNMT1-241 ENST00000677946 5665 1655aa ENSP00000504202
DNMT1-244 ENST00000678239 2117 No protein -
DNMT1-217 ENST00000589294 575 No protein -
DNMT1-211 ENST00000587197 809 No protein -
DNMT1-220 ENST00000589538 559 No protein -
DNMT1-228 ENST00000593049 534 No protein -
DNMT1-212 ENST00000587604 513 No protein -
DNMT1-216 ENST00000589091 563 No protein -
DNMT1-222 ENST00000591239 550 No protein -
DNMT1-208 ENST00000586799 672 55aa ENSP00000467260
DNMT1-203 ENST00000585843 911 No protein -
DNMT1-218 ENST00000589349 603 No protein -
DNMT1-223 ENST00000591764 341 No protein -
DNMT1-204 ENST00000585920 529 No protein -
DNMT1-210 ENST00000586988 711 40aa ENSP00000464958
DNMT1-215 ENST00000588952 841 119aa ENSP00000467050
DNMT1-213 ENST00000588118 973 255aa ENSP00000465223
DNMT1-226 ENST00000592342 636 94aa ENSP00000465993
DNMT1-225 ENST00000592054 591 71aa ENSP00000468359
DNMT1-221 ENST00000590619 231 77aa ENSP00000468062
DNMT1-209 ENST00000586800 583 25aa ENSP00000465555
DNMT1-205 ENST00000586086 489 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
50694Child Development Disorders, Pervasive4.2719400E-005-
70591Hydrochlorothiazide3E-623400010
70592Triglycerides3E-623400010

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000130816homo_sapiensENSP0000036703047.826127.3657homo_sapiensENSP0000035251611.45836.55637

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000130816homo_sapiensENSP0000035251696.139795.2206nomascus_leucogenysENSNLEP0000002739095.32294.4107
ENSG00000130816homo_sapiensENSP0000035251696.997696.8137pan_paniscusENSPPAP0000000860496.701396.518
ENSG00000130816homo_sapiensENSP0000035251699.754999.4485pongo_abeliiENSPPYP0000001070699.754999.4485
ENSG00000130816homo_sapiensENSP0000035251699.448599.2647pan_troglodytesENSPTRP0000008569996.953496.7742
ENSG00000130816homo_sapiensENSP0000035251699.448599.2647pan_troglodytesENSPTRP0000006603496.953496.7742
ENSG00000130816homo_sapiensENSP0000035251696.507496.0784gorilla_gorillaENSGGOP0000001618694.99494.5718
ENSG00000130816homo_sapiensENSP0000035251673.161864.0931ornithorhynchus_anatinusENSOANP0000001939379.866269.9666
ENSG00000130816homo_sapiensENSP0000035251679.840772.7328sarcophilus_harrisiiENSSHAP0000001029975.230968.5335
ENSG00000130816homo_sapiensENSP0000035251625.428921.5074sarcophilus_harrisiiENSSHAP0000002986981.054768.5547
ENSG00000130816homo_sapiensENSP0000035251655.085848.223notamacropus_eugeniiENSMEUP0000000737155.803848.8516
ENSG00000130816homo_sapiensENSP0000035251635.968132.9044notamacropus_eugeniiENSMEUP0000001154357.324252.4414
ENSG00000130816homo_sapiensENSP0000035251657.843154.7181choloepus_hoffmanniENSCHOP0000000842064.217760.7483
ENSG00000130816homo_sapiensENSP0000035251680.759875.8578dasypus_novemcinctusENSDNOP0000000257184.002578.9038
ENSG00000130816homo_sapiensENSP0000035251651.164244.9755erinaceus_europaeusENSEEUP0000001053066.746658.6731
ENSG00000130816homo_sapiensENSP0000035251660.416754.8407echinops_telfairiENSETEP0000001020162.405156.6456
ENSG00000130816homo_sapiensENSP0000035251697.365296.0172callithrix_jacchusENSCJAP0000001080898.329296.9678
ENSG00000130816homo_sapiensENSP0000035251698.65298.223cercocebus_atysENSCATP0000001398998.65298.223
ENSG00000130816homo_sapiensENSP0000035251698.039297.6716macaca_fascicularisENSMFAP0000001307093.185892.8363
ENSG00000130816homo_sapiensENSP0000035251698.039297.6716macaca_mulattaENSMMUP0000001917093.185892.8363
ENSG00000130816homo_sapiensENSP0000035251697.54997.1201macaca_nemestrinaENSMNEP0000000989292.990792.5818
ENSG00000130816homo_sapiensENSP0000035251697.916797.6716papio_anubisENSPANP0000000013398.886198.6386
ENSG00000130816homo_sapiensENSP0000035251694.975594.1789mandrillus_leucophaeusENSMLEP0000002936997.484396.6667
ENSG00000130816homo_sapiensENSP0000035251684.436379.7181tursiops_truncatusENSTTRP0000000297985.483980.7072
ENSG00000130816homo_sapiensENSP0000035251687.584.3137vulpes_vulpesENSVVUP0000004062794.820791.3679
ENSG00000130816homo_sapiensENSP0000035251686.642277.3284mus_spretusMGP_SPRETEiJ_P009046887.28477.9012
ENSG00000130816homo_sapiensENSP0000035251694.607890.1348equus_asinusENSEASP0000501511990.239685.9731
ENSG00000130816homo_sapiensENSP0000035251691.115286.2745capra_hircusENSCHIP0000002735993.463288.4978
ENSG00000130816homo_sapiensENSP0000035251694.178991.1765loxodonta_africanaENSLAFP0000000235994.410391.4005
ENSG00000130816homo_sapiensENSP0000035251694.669190.9314panthera_leoENSPLOP0000000444290.350986.7836
ENSG00000130816homo_sapiensENSP0000035251694.607890.4412ailuropoda_melanoleucaENSAMEP0000001257692.900188.8087
ENSG00000130816homo_sapiensENSP0000035251693.198588.3578bos_indicus_hybridENSBIXP0000504272789.051584.4262
ENSG00000130816homo_sapiensENSP0000035251694.546690.0123equus_caballusENSECAP0000003526790.181285.8562
ENSG00000130816homo_sapiensENSP0000035251694.362790.2574canis_lupus_familiarisENSCAFP0084502523895.592891.4339
ENSG00000130816homo_sapiensENSP0000035251694.669190.9314panthera_pardusENSPPRP0000000886395.784392.0025
ENSG00000130816homo_sapiensENSP0000035251685.539281.4338marmota_marmota_marmotaENSMMMP0000001914392.819188.3644
ENSG00000130816homo_sapiensENSP0000035251693.504988.5417balaenoptera_musculusENSBMSP0001001636094.197589.1975
ENSG00000130816homo_sapiensENSP0000035251686.213279.5343cavia_porcellusENSCPOP0000001901387.937581.125
ENSG00000130816homo_sapiensENSP0000035251694.669190.9314felis_catusENSFCAP0000004400290.350986.7836
ENSG00000130816homo_sapiensENSP0000035251656.066254.2892ursus_americanusENSUAMP0000000848593.272290.316
ENSG00000130816homo_sapiensENSP000003525167567.0343monodelphis_domesticaENSMODP0000005341684.413875.4483
ENSG00000130816homo_sapiensENSP0000035251680.637372.7941monodelphis_domesticaENSMODP0000000665786.922178.4676
ENSG00000130816homo_sapiensENSP0000035251693.07688.2966bison_bison_bisonENSBBBP0000000717594.230889.3921
ENSG00000130816homo_sapiensENSP0000035251693.382488.4804monodon_monocerosENSMMNP0001502904394.423889.4672
ENSG00000130816homo_sapiensENSP0000035251693.198588.174sus_scrofaENSSSCP0000001452290.643685.7569
ENSG00000130816homo_sapiensENSP0000035251695.588292.5858microcebus_murinusENSMICP0000000933896.714293.6764
ENSG00000130816homo_sapiensENSP0000035251687.193680.8824octodon_degusENSODEP0000002308290.349283.8095
ENSG00000130816homo_sapiensENSP0000035251687.438781.0049jaculus_jaculusENSJJAP0000002045492.005285.2353
ENSG00000130816homo_sapiensENSP0000035251693.259888.2966ovis_aries_rambouilletENSOARP0002000470089.110184.3677
ENSG00000130816homo_sapiensENSP0000035251687.622683.6397ursus_maritimusENSUMAP0000003489495.780391.4267
ENSG00000130816homo_sapiensENSP0000035251679.044173.5294ochotona_princepsENSOPRP0000000646580.024874.4417
ENSG00000130816homo_sapiensENSP0000035251693.382488.5417delphinapterus_leucasENSDLEP0000001177387.485682.9506
ENSG00000130816homo_sapiensENSP0000035251693.259888.4804physeter_catodonENSPCTP0000500944394.534289.6894
ENSG00000130816homo_sapiensENSP0000035251680.637371.875mus_caroliMGP_CAROLIEiJ_P008691587.616578.0959
ENSG00000130816homo_sapiensENSP0000035251686.764777.5123mus_musculusENSMUSP0000000420287.407478.0864
ENSG00000130816homo_sapiensENSP0000035251684.681478.5539dipodomys_ordiiENSDORP0000001327487.857681.5003
ENSG00000130816homo_sapiensENSP0000035251692.708388.6642mustela_putorius_furoENSMPUP0000000677590.382386.4397
ENSG00000130816homo_sapiensENSP0000035251697.487796.0172aotus_nancymaaeENSANAP0000001391998.270596.7881
ENSG00000130816homo_sapiensENSP0000035251697.058895.7721saimiri_boliviensis_boliviensisENSSBOP0000003845192.415491.1902
ENSG00000130816homo_sapiensENSP0000035251648.345645.6495vicugna_pacosENSVPAP0000000567850.641847.8177
ENSG00000130816homo_sapiensENSP0000035251698.100597.549chlorocebus_sabaeusENSCSAP0000000364799.071898.5149
ENSG00000130816homo_sapiensENSP0000035251669.117666.1152tupaia_belangeriENSTBEP0000000638069.500966.4818
ENSG00000130816homo_sapiensENSP0000035251685.110377.3284mesocricetus_auratusENSMAUP0000002208186.866878.9243
ENSG00000130816homo_sapiensENSP0000035251693.382488.4804phocoena_sinusENSPSNP0000002743794.01689.0808
ENSG00000130816homo_sapiensENSP0000035251694.056489.5833camelus_dromedariusENSCDRP0000500906995.105390.5824
ENSG00000130816homo_sapiensENSP0000035251682.475580.8824carlito_syrichtaENSTSYP0000000823497.890996
ENSG00000130816homo_sapiensENSP0000035251688.786884.375panthera_tigris_altaicaENSPTIP0000001705989.224184.7906
ENSG00000130816homo_sapiensENSP0000035251687.071178.4314rattus_norvegicusENSRNOP0000006383187.661978.9636
ENSG00000130816homo_sapiensENSP0000035251693.995190.8701prolemur_simusENSPSMP0000002945693.026189.9333
ENSG00000130816homo_sapiensENSP0000035251686.029477.8186microtus_ochrogasterENSMOCP0000001444086.827578.5405
ENSG00000130816homo_sapiensENSP0000035251674.938768.8726sorex_araneusENSSARP0000000620378.097171.7752
ENSG00000130816homo_sapiensENSP0000035251673.897163.4804peromyscus_maniculatus_bairdiiENSPEMP0000003151080.346469.0207
ENSG00000130816homo_sapiensENSP0000035251687.009879.2892peromyscus_maniculatus_bairdiiENSPEMP0000000371388.089380.2729
ENSG00000130816homo_sapiensENSP0000035251691.053985.9681bos_mutusENSBMUP0000002788087.617982.7241
ENSG00000130816homo_sapiensENSP0000035251686.580977.3897mus_spicilegusENSMSIP0000002061087.222277.963
ENSG00000130816homo_sapiensENSP0000035251683.884875.3064cricetulus_griseus_chok1gshdENSCGRP0000102436186.645677.7848
ENSG00000130816homo_sapiensENSP0000035251692.585888.5417pteropus_vampyrusENSPVAP0000000347793.850989.7516
ENSG00000130816homo_sapiensENSP0000035251689.27782.7206myotis_lucifugusENSMLUP0000000125491.405384.6926
ENSG00000130816homo_sapiensENSP0000035251675.612768.6274vombatus_ursinusENSVURP0001003269989.226380.9834
ENSG00000130816homo_sapiensENSP0000035251627.512323.7745vombatus_ursinusENSVURP0001003270380.46669.534
ENSG00000130816homo_sapiensENSP0000035251694.791790.5024neovison_visonENSNVIP0000003086595.848891.5118
ENSG00000130816homo_sapiensENSP0000035251693.198588.3578bos_taurusENSBTAP0000000354992.518287.7129
ENSG00000130816homo_sapiensENSP0000035251673.161868.75heterocephalus_glaber_femaleENSHGLP0000004614892.414986.8421
ENSG00000130816homo_sapiensENSP0000035251685.968185.5392rhinopithecus_bietiENSRBIP0000002836994.669494.197
ENSG00000130816homo_sapiensENSP0000035251666.360360.7843canis_lupus_dingoENSCAFP0002003122680.941774.1405
ENSG00000130816homo_sapiensENSP0000035251693.321188.7255sciurus_vulgarisENSSVLP0000502516394.537689.8821
ENSG00000130816homo_sapiensENSP0000035251680.759872.7941phascolarctos_cinereusENSPCIP0000002493187.054278.4676
ENSG00000130816homo_sapiensENSP0000035251626.531923.4681phascolarctos_cinereusENSPCIP0000002493382.633673.0916
ENSG00000130816homo_sapiensENSP0000035251691.727989.0931procavia_capensisENSPCAP0000001049392.179889.532
ENSG00000130816homo_sapiensENSP0000035251685.784379.3505nannospalax_galiliENSNGAP0000000705387.99581.3953
ENSG00000130816homo_sapiensENSP0000035251693.198588.3578bos_grunniensENSBGRP0000000388894.413489.5096
ENSG00000130816homo_sapiensENSP0000035251691.237784.6814chinchilla_lanigeraENSCLAP0000001384590.626984.1144
ENSG00000130816homo_sapiensENSP0000035251692.769687.8676cervus_hanglu_yarkandensisENSCHYP0000000229793.920688.9578
ENSG00000130816homo_sapiensENSP0000035251693.07688.3578catagonus_wagneriENSCWAP0000000596292.396687.7129
ENSG00000130816homo_sapiensENSP0000035251686.887382.1078ictidomys_tridecemlineatusENSSTOP0000002533392.558787.4674
ENSG00000130816homo_sapiensENSP0000035251693.07689.7672otolemur_garnettiiENSOGAP0000000113295.715292.3125
ENSG00000130816homo_sapiensENSP0000035251697.365295.8333cebus_imitatorENSCCAP0000003370797.604496.0688
ENSG00000130816homo_sapiensENSP0000035251627.022125.6127cebus_imitatorENSCCAP0000003777585.135180.695
ENSG00000130816homo_sapiensENSP0000035251679.227974.5098urocitellus_parryiiENSUPAP0001000099991.249185.8151
ENSG00000130816homo_sapiensENSP0000035251691.421686.3358moschus_moschiferusENSMMSP0000000371190.64485.6015
ENSG00000130816homo_sapiensENSP0000035251641.176540.7475rhinopithecus_roxellanaENSRROP0000004238797.250496.2373
ENSG00000130816homo_sapiensENSP0000035251698.039297.6103rhinopithecus_roxellanaENSRROP0000002995496.096195.6757
ENSG00000130816homo_sapiensENSP0000035251687.254977.8799mus_pahariMGP_PahariEiJ_P002256387.955578.5052
ENSG00000130816homo_sapiensENSP0000035251696.384893.5049propithecus_coquereliENSPCOP0000001351397.399494.4892
ENSG00000130816homo_sapiensENSP0000035251655.085844.424ciona_intestinalisENSCINP0000001079771.519557.677
ENSG00000130816homo_sapiensENSP0000035251627.757425.7966petromyzon_marinusENSPMAP0000000285986.450480.3435
ENSG00000130816homo_sapiensENSP000003525166.372555.14706eptatretus_burgeriENSEBUP0000001081668.421155.2632
ENSG00000130816homo_sapiensENSP0000035251646.384838.6029eptatretus_burgeriENSEBUP0000002735672.026659.9429
ENSG00000130816homo_sapiensENSP0000035251616.29914.4608eptatretus_burgeriENSEBUP0000000381279.40370.4478
ENSG00000130816homo_sapiensENSP0000035251675.857865.7476callorhinchus_miliiENSCMIP0000001748182.041171.1067
ENSG00000130816homo_sapiensENSP0000035251665.502458.2721latimeria_chalumnaeENSLACP0000001250283.974974.7054
ENSG00000130816homo_sapiensENSP0000035251675.428965.5637lepisosteus_oculatusENSLOCP0000000905377.862167.6787
ENSG00000130816homo_sapiensENSP0000035251674.264763.4191clupea_harengusENSCHAP0000003518079.947268.2718
ENSG00000130816homo_sapiensENSP0000035251674.877465.4412danio_rerioENSDARP0000001324381.466771.2
ENSG00000130816homo_sapiensENSP000003525167565.7476carassius_auratusENSCARP0000009134481.545671.4857
ENSG00000130816homo_sapiensENSP0000035251674.877465.6863carassius_auratusENSCARP0000008804681.142171.1819
ENSG00000130816homo_sapiensENSP0000035251674.693665.2574carassius_auratusENSCARP0000012103280.835570.6233
ENSG00000130816homo_sapiensENSP0000035251673.713264.2157astyanax_mexicanusENSAMXP0000001256181.393870.9066
ENSG00000130816homo_sapiensENSP0000035251675.061365.5637ictalurus_punctatusENSIPUP0000000700981.341371.0491
ENSG00000130816homo_sapiensENSP0000035251675.061364.4608esox_luciusENSELUP0000002496080.065468.7582
ENSG00000130816homo_sapiensENSP0000035251673.161863.7255electrophorus_electricusENSEEEP0000004197880.18869.8455
ENSG00000130816homo_sapiensENSP0000035251674.080962.8064oncorhynchus_kisutchENSOKIP0000500474378.710966.7318
ENSG00000130816homo_sapiensENSP0000035251674.877463.7868oncorhynchus_kisutchENSOKIP0000508203579.869368.0392
ENSG00000130816homo_sapiensENSP0000035251675.428963.9706oncorhynchus_mykissENSOMYP0000009210580.668468.4142
ENSG00000130816homo_sapiensENSP0000035251674.019663.3578oncorhynchus_mykissENSOMYP0000009265878.954267.5817
ENSG00000130816homo_sapiensENSP0000035251674.693663.2966salmo_salarENSSSAP0000002032280.621768.3201
ENSG00000130816homo_sapiensENSP0000035251675.122664.1544salmo_salarENSSSAP0000003849680.078468.3867
ENSG00000130816homo_sapiensENSP0000035251675.306463.848salmo_truttaENSSTUP0000003222480.431968.1937
ENSG00000130816homo_sapiensENSP0000035251674.816264.0319salmo_truttaENSSTUP0000004008976.647865.5995
ENSG00000130816homo_sapiensENSP0000035251673.897162.3775gadus_morhuaENSGMOP0000003559977.357365.2983
ENSG00000130816homo_sapiensENSP0000035251674.632463.6642fundulus_heteroclitusENSFHEP0000000083080.98469.0824
ENSG00000130816homo_sapiensENSP0000035251674.448563.6029poecilia_reticulataENSPREP0000000969780.570368.8329
ENSG00000130816homo_sapiensENSP0000035251674.203463.6029xiphophorus_maculatusENSXMAP0000004062980.787269.2462
ENSG00000130816homo_sapiensENSP0000035251674.571163.7868oryzias_latipesENSORLP0000003401681.350369.5856
ENSG00000130816homo_sapiensENSP0000035251674.571162.8064cyclopterus_lumpusENSCLMP0000504752781.133368.3333
ENSG00000130816homo_sapiensENSP0000035251674.816263.9706oreochromis_niloticusENSONIP0000002911380.860969.1391
ENSG00000130816homo_sapiensENSP0000035251674.571163.7868haplochromis_burtoniENSHBUP0000003411980.756569.0776
ENSG00000130816homo_sapiensENSP0000035251674.509863.7255astatotilapia_callipteraENSACLP0000002797480.690169.0113
ENSG00000130816homo_sapiensENSP0000035251674.877464.0931sparus_aurataENSSAUP0001004328479.453868.0104
ENSG00000130816homo_sapiensENSP0000035251675.245164.7672lates_calcariferENSLCAP0001005600681.270769.9537
ENSG00000130816homo_sapiensENSP0000035251678.553968.75xenopus_tropicalisENSXETP0000004770385.924975.2011
ENSG00000130816homo_sapiensENSP0000035251674.816267.1569chrysemys_picta_belliiENSCPBP0000000685487.841778.8489
ENSG00000130816homo_sapiensENSP0000035251664.460856.1887sphenodon_punctatusENSSPUP0000001343479.097768.9474
ENSG00000130816homo_sapiensENSP0000035251674.387365.6863laticauda_laticaudataENSLLTP0000000007686.652476.5168
ENSG00000130816homo_sapiensENSP0000035251676.593167.7696notechis_scutatusENSNSUP0000001967985.207975.392
ENSG00000130816homo_sapiensENSP0000035251679.656969.7304pseudonaja_textilisENSPTXP0000000660885.357874.7209
ENSG00000130816homo_sapiensENSP0000035251673.22365.8088anas_platyrhynchos_platyrhynchosENSAPLP0000000203485.540476.879
ENSG00000130816homo_sapiensENSP0000035251679.105470.5882gallus_gallusENSGALP0001000404580.73872.045
ENSG00000130816homo_sapiensENSP0000035251662.254954.7794meleagris_gallopavoENSMGAP0000002984080.126270.5047
ENSG00000130816homo_sapiensENSP0000035251656.127548.9583serinus_canariaENSSCAP0000001065080.210269.965
ENSG00000130816homo_sapiensENSP0000035251679.105469.424anolis_carolinensisENSACAP0000000404182.334272.2577
ENSG00000130816homo_sapiensENSP0000035251674.32663.7255neolamprologus_brichardiENSNBRP0000001273981.028769.4723
ENSG00000130816homo_sapiensENSP0000035251679.718169.6691naja_najaENSNNAP0000002945385.423574.6553
ENSG00000130816homo_sapiensENSP0000035251679.840769.9755podarcis_muralisENSPMRP0000003684085.498774.9344
ENSG00000130816homo_sapiensENSP0000035251672.365263.5417geospiza_fortisENSGFOP0000000652780.559370.7367
ENSG00000130816homo_sapiensENSP0000035251675.183866.8505taeniopygia_guttataENSTGUP0000003161681.636772.5882
ENSG00000130816homo_sapiensENSP0000035251672.242663.7255erpetoichthys_calabaricusENSECRP0000002423783.854973.9687
ENSG00000130816homo_sapiensENSP0000035251674.877463.9706kryptolebias_marmoratusENSKMAP0000002314681.088369.2767
ENSG00000130816homo_sapiensENSP0000035251678.860369.3015salvator_merianaeENSSMRP0000002154184.615474.359
ENSG00000130816homo_sapiensENSP0000035251675.183863.848amphilophus_citrinellusENSACIP0000001093381.4269.144
ENSG00000130816homo_sapiensENSP0000035251674.32663.5417dicentrarchus_labraxENSDLAP0000507363779.802668.2237
ENSG00000130816homo_sapiensENSP0000035251674.387363.7255amphiprion_perculaENSAPEP0000001490880.397468.8742
ENSG00000130816homo_sapiensENSP0000035251669.301560.4167oryzias_sinensisENSOSIP0000001327582.978772.3404
ENSG00000130816homo_sapiensENSP0000035251664.705955.8824pelodiscus_sinensisENSPSIP0000000302576.245565.8484
ENSG00000130816homo_sapiensENSP0000035251679.105470.6495gopherus_evgoodeiENSGEVP0000502780884.711375.6562
ENSG00000130816homo_sapiensENSP0000035251678.002469.9142chelonoidis_abingdoniiENSCABP0000002408184.081975.3633
ENSG00000130816homo_sapiensENSP0000035251675.061364.3382seriola_dumeriliENSSDUP0000002947881.341369.7211
ENSG00000130816homo_sapiensENSP0000035251674.938763.0515cottoperca_gobioENSCGOP0000001894681.370668.4631
ENSG00000130816homo_sapiensENSP0000035251657.720651.7157struthio_camelus_australisENSSCUP0000002065285.018176.1733
ENSG00000130816homo_sapiensENSP0000035251675.306467.7696anser_brachyrhynchusENSABRP0000000104088.100479.2832
ENSG00000130816homo_sapiensENSP0000035251674.754963.2353gasterosteus_aculeatusENSGACP0000001817281.009368.5259
ENSG00000130816homo_sapiensENSP0000035251669.914259.8652cynoglossus_semilaevisENSCSEP0000003282879.567668.1311
ENSG00000130816homo_sapiensENSP0000035251674.754963.9706poecilia_formosaENSPFOP0000000622281.17169.4611
ENSG00000130816homo_sapiensENSP0000035251674.754964.3995myripristis_murdjanENSMMDP0000500172880.901969.695
ENSG00000130816homo_sapiensENSP0000035251675.122663.848sander_luciopercaENSSLUP0000002129781.678969.4204
ENSG00000130816homo_sapiensENSP0000035251676.409368.3824strigops_habroptilaENSSHBP0000501936976.362568.3405
ENSG00000130816homo_sapiensENSP0000035251674.509863.848amphiprion_ocellarisENSAOCP0000002088580.529869.0066
ENSG00000130816homo_sapiensENSP0000035251679.779470.8946terrapene_carolina_triunguisENSTMTP0000000478585.883976.3193
ENSG00000130816homo_sapiensENSP0000035251675.367664.0931hucho_huchoENSHHUP0000007364181.027768.9065
ENSG00000130816homo_sapiensENSP0000035251671.507460.6618hucho_huchoENSHHUP0000007044579.011567.0278
ENSG00000130816homo_sapiensENSP0000035251675.367664.3995betta_splendensENSBSLP0000003309281.45769.6026
ENSG00000130816homo_sapiensENSP0000035251675.245165.8701pygocentrus_nattereriENSPNAP0000003044881.270771.1449
ENSG00000130816homo_sapiensENSP0000035251675.306464.8284anabas_testudineusENSATEP0000003065181.498770.1591
ENSG00000130816homo_sapiensENSP0000035251654.227943.8113ciona_savignyiENSCSAVP0000001017270.182456.701
ENSG00000130816homo_sapiensENSP0000035251674.693664.1544seriola_lalandi_dorsalisENSSLDP0000002045781.158569.7071
ENSG00000130816homo_sapiensENSP0000035251671.629961.2745labrus_bergyltaENSLBEP0000002745882.556570.6215
ENSG00000130816homo_sapiensENSP0000035251674.632463.848pundamilia_nyerereiENSPNYP0000001817181.145969.4204
ENSG00000130816homo_sapiensENSP0000035251675.490264.4608mastacembelus_armatusENSMAMP0000001832681.806169.8539
ENSG00000130816homo_sapiensENSP0000035251674.754963.7868stegastes_partitusENSSPAP0000000059281.11769.2154
ENSG00000130816homo_sapiensENSP0000035251670.772160.2941oncorhynchus_tshawytschaENSOTSP0000507357379.875568.0498
ENSG00000130816homo_sapiensENSP0000035251675.245163.9093oncorhynchus_tshawytschaENSOTSP0000505427280.156768.0809
ENSG00000130816homo_sapiensENSP0000035251674.571163.9093acanthochromis_polyacanthusENSAPOP0000001461780.649469.1186
ENSG00000130816homo_sapiensENSP0000035251674.754967.2181aquila_chrysaetos_chrysaetosENSACCP0002000191681.879273.6242
ENSG00000130816homo_sapiensENSP0000035251674.32663.9706cyprinodon_variegatusENSCVAP0000002734480.812869.5536
ENSG00000130816homo_sapiensENSP0000035251670.588261.7647denticeps_clupeoidesENSDCDP0000002600776.392666.8435
ENSG00000130816homo_sapiensENSP0000035251674.693663.7868larimichthys_croceaENSLCRP0000501362580.621768.8492
ENSG00000130816homo_sapiensENSP0000035251674.019662.9902takifugu_rubripesENSTRUP0000002032277.535365.982
ENSG00000130816homo_sapiensENSP0000035251662.745156.4951ficedula_albicollisENSFALP0000000812484.418876.0099
ENSG00000130816homo_sapiensENSP0000035251673.958363.3578hippocampus_comesENSHCOP0000001343981.279569.6296
ENSG00000130816homo_sapiensENSP0000035251674.938765.3799cyprinus_carpio_carpioENSCCRP0000017624881.100870.756
ENSG00000130816homo_sapiensENSP0000035251675.122665.9314cyprinus_carpio_carpioENSCCRP0000014465379.713969.961
ENSG00000130816homo_sapiensENSP0000035251662.990255.2696coturnix_japonicaENSCJPP0000500517880.187270.3588
ENSG00000130816homo_sapiensENSP0000035251674.754963.9706poecilia_latipinnaENSPLAP0000001703081.17169.4611
ENSG00000130816homo_sapiensENSP0000035251672.303963.4191sinocyclocheilus_grahamiENSSGRP0000009063879.783669.9797
ENSG00000130816homo_sapiensENSP0000035251674.571164.8897sinocyclocheilus_grahamiENSSGRP0000003742580.971470.4591
ENSG00000130816homo_sapiensENSP0000035251674.632463.848maylandia_zebraENSMZEP0000502533481.091969.3742
ENSG00000130816homo_sapiensENSP0000035251668.382460.049tetraodon_nigroviridisENSTNIP0000001902983.035772.9167
ENSG00000130816homo_sapiensENSP0000035251626.164223.223paramormyrops_kingsleyaeENSPKIP0000002871885.915576.2575
ENSG00000130816homo_sapiensENSP0000035251611.090710.1103paramormyrops_kingsleyaeENSPKIP0000003717489.162681.2808
ENSG00000130816homo_sapiensENSP0000035251675.183865.3186scleropages_formosusENSSFOP0001504832981.043670.4095
ENSG00000130816homo_sapiensENSP0000035251675.67466.6054leptobrachium_leishanenseENSLLEP0000000678382.608772.709
ENSG00000130816homo_sapiensENSP0000035251675.061364.4608scophthalmus_maximusENSSMAP0000000673581.449569.9468
ENSG00000130816homo_sapiensENSP0000035251674.264763.2966oryzias_melastigmaENSOMEP0000000006480.961969.0047

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000122involved_in negative regulation of transcription by RNA polymerase II1IEAHomo_sapiens(9606)Process
GO:0001674located_in female germ cell nucleus1IEAHomo_sapiens(9606)Component
GO:0003677enables DNA binding2IBA,IDAHomo_sapiens(9606)Function
GO:0003723enables RNA binding1IEAHomo_sapiens(9606)Function
GO:0003886enables DNA (cytosine-5-)-methyltransferase activity2IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus2HDA,IBAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1TASHomo_sapiens(9606)Component
GO:0005657located_in replication fork1IEAHomo_sapiens(9606)Component
GO:0005721part_of pericentric heterochromatin1IEAHomo_sapiens(9606)Component
GO:0006346involved_in DNA methylation-dependent heterochromatin formation1IEAHomo_sapiens(9606)Process
GO:0006351involved_in DNA-templated transcription1IEAHomo_sapiens(9606)Process
GO:0008270enables zinc ion binding1IEAHomo_sapiens(9606)Function
GO:0008327enables methyl-CpG binding1IEAHomo_sapiens(9606)Function
GO:0009008enables DNA-methyltransferase activity1IDAHomo_sapiens(9606)Function
GO:0010424involved_in DNA methylation on cytosine within a CG sequence1IBAHomo_sapiens(9606)Process
GO:0010628involved_in positive regulation of gene expression1IMPHomo_sapiens(9606)Process
GO:0010629involved_in negative regulation of gene expression1IMPHomo_sapiens(9606)Process
GO:0043045involved_in post-fertilization epigenetic regulation of gene expression1IEAHomo_sapiens(9606)Process
GO:0044027involved_in negative regulation of gene expression via CpG island methylation2IDA,IMPHomo_sapiens(9606)Process
GO:0071230involved_in cellular response to amino acid stimulus1IEAHomo_sapiens(9606)Process
GO:0090116involved_in C-5 methylation of cytosine1IEAHomo_sapiens(9606)Process
GO:1903926involved_in cellular response to bisphenol A1IEAHomo_sapiens(9606)Process
GO:1904707involved_in positive regulation of vascular associated smooth muscle cell proliferation1IMPHomo_sapiens(9606)Process
GO:1905460involved_in negative regulation of vascular associated smooth muscle cell apoptotic process1IMPHomo_sapiens(9606)Process
GO:1905931involved_in negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching1IMPHomo_sapiens(9606)Process
GO:1990841enables promoter-specific chromatin binding1IDAHomo_sapiens(9606)Function

Expression