Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000126254 Gene ID 79171 Accession 28117
Symbol RBM42 Alias NA Full Name RNA binding motif protein 42
Status Confidence Length 8657 bases Strand Plus strand
Position 19 : 35629030 - 35637686 RNA binding domain RRM_1
Summary Enables RNA binding activity. Predicted to act upstream of or within negative regulation of mRNA splicing, via spliceosome. Predicted to be located in cytoplasm and nucleus. Predicted to be part of ribonucleoprotein complex. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000467614 RRM_1 PF00076 7.9e-17 1
ENSP00000466044 RRM_1 PF00076 8.5e-17 1
ENSP00000467278 RRM_1 PF00076 8.7e-17 1
ENSP00000262633 RRM_1 PF00076 9.4e-17 1
ENSP00000466548 RRM_1 PF00076 2.8e-10 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
31142587 c-MYC regulates mRNA translation efficiency and start-site selection in lymphoma. Kamini Singh 2019-07-01 The Journal of experimental medicine
37294900 Biallelic variants in RBM42 cause a multisystem disorder with neurological, facial, cardiac, and musculoskeletal involvement. Yiyao Chen 2023-06-09 Protein & cell

Transcripts

Name Transcript ID bp Protein Translation ID
RBM42-203 ENST00000588161 1609 450aa ENSP00000466044
RBM42-201 ENST00000262633 1692 480aa ENSP00000262633
RBM42-206 ENST00000592202 1469 426aa ENSP00000467614
RBM42-202 ENST00000586618 771 184aa ENSP00000466548
RBM42-204 ENST00000589559 1328 386aa ENSP00000468060
RBM42-207 ENST00000592526 1012 No protein -
RBM42-205 ENST00000589871 1487 458aa ENSP00000467278

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000126254

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000126254homo_sapiensENSP0000026263377.083373.5417nomascus_leucogenysENSNLEP0000001368986.651182.6698
ENSG00000126254homo_sapiensENSP0000026263399.166799.1667pan_paniscusENSPPAP0000002859699.373799.3737
ENSG00000126254homo_sapiensENSP00000262633100100pongo_abeliiENSPPYP0000001105198.969198.9691
ENSG00000126254homo_sapiensENSP00000262633100100pan_troglodytesENSPTRP00000018580100100
ENSG00000126254homo_sapiensENSP00000262633100100gorilla_gorillaENSGGOP00000019806100100
ENSG00000126254homo_sapiensENSP0000026263379.37575.625ornithorhynchus_anatinusENSOANP0000003431086.199182.1267
ENSG00000126254homo_sapiensENSP0000026263384.37582.7083sarcophilus_harrisiiENSSHAP0000004285492.045590.2273
ENSG00000126254homo_sapiensENSP0000026263388.333386.25notamacropus_eugeniiENSMEUP0000001490590.405188.2729
ENSG00000126254homo_sapiensENSP0000026263395.208393.75dasypus_novemcinctusENSDNOP0000003247592.323290.9091
ENSG00000126254homo_sapiensENSP0000026263363.541761.875echinops_telfairiENSETEP0000000639668.232766.443
ENSG00000126254homo_sapiensENSP0000026263399.166798.9583callithrix_jacchusENSCJAP0000006468699.790499.5807
ENSG00000126254homo_sapiensENSP0000026263399.791799.7917cercocebus_atysENSCATP0000003851599.791799.7917
ENSG00000126254homo_sapiensENSP0000026263399.583399.375macaca_fascicularisENSMFAP0000003556499.791299.5825
ENSG00000126254homo_sapiensENSP0000026263399.791799.7917macaca_mulattaENSMMUP0000002494399.791799.7917
ENSG00000126254homo_sapiensENSP0000026263399.791799.7917macaca_nemestrinaENSMNEP0000001157499.791799.7917
ENSG00000126254homo_sapiensENSP0000026263399.791799.7917papio_anubisENSPANP0000003024799.791799.7917
ENSG00000126254homo_sapiensENSP0000026263399.791799.7917mandrillus_leucophaeusENSMLEP0000002409799.791799.7917
ENSG00000126254homo_sapiensENSP0000026263367.291767.0833tursiops_truncatusENSTTRP0000000207383.678883.4197
ENSG00000126254homo_sapiensENSP0000026263396.666796.4583vulpes_vulpesENSVVUP0000002054399.145398.9316
ENSG00000126254homo_sapiensENSP0000026263397.291797.0833mus_spretusMGP_SPRETEiJ_P008207397.698797.4895
ENSG00000126254homo_sapiensENSP0000026263397.916797.9167equus_asinusENSEASP0000503957499.156199.1561
ENSG00000126254homo_sapiensENSP0000026263397.708397.5capra_hircusENSCHIP0000000551598.322998.1132
ENSG00000126254homo_sapiensENSP0000026263395.833395loxodonta_africanaENSLAFP0000001255396.842196
ENSG00000126254homo_sapiensENSP0000026263398.333398.125panthera_leoENSPLOP0000002225998.951898.7421
ENSG00000126254homo_sapiensENSP0000026263397.916797.7083ailuropoda_melanoleucaENSAMEP0000003410898.532598.3229
ENSG00000126254homo_sapiensENSP0000026263398.333398.125bos_indicus_hybridENSBIXP0000502916898.951898.7421
ENSG00000126254homo_sapiensENSP0000026263397.708397.2917oryctolagus_cuniculusENSOCUP0000004547598.736898.3158
ENSG00000126254homo_sapiensENSP0000026263397.916797.9167equus_caballusENSECAP0000005337599.156199.1561
ENSG00000126254homo_sapiensENSP0000026263398.12597.9167canis_lupus_familiarisENSCAFP0084500293799.157998.9474
ENSG00000126254homo_sapiensENSP0000026263398.333398.125panthera_pardusENSPPRP0000002612598.951898.7421
ENSG00000126254homo_sapiensENSP0000026263398.12598.125marmota_marmota_marmotaENSMMMP0000000636997.92197.921
ENSG00000126254homo_sapiensENSP0000026263397.916797.7083balaenoptera_musculusENSBMSP0001001961998.532598.3229
ENSG00000126254homo_sapiensENSP0000026263398.12597.5cavia_porcellusENSCPOP0000001112797.92197.2973
ENSG00000126254homo_sapiensENSP0000026263398.333398.125felis_catusENSFCAP0000004550198.951898.7421
ENSG00000126254homo_sapiensENSP0000026263397.916797.7083ursus_americanusENSUAMP0000002677598.532598.3229
ENSG00000126254homo_sapiensENSP0000026263388.958387.0833monodelphis_domesticaENSMODP0000001745290.466188.5593
ENSG00000126254homo_sapiensENSP0000026263398.12597.9167bison_bison_bisonENSBBBP0000001550898.742198.5325
ENSG00000126254homo_sapiensENSP0000026263397.708397.5monodon_monocerosENSMMNP0001500609898.322998.1132
ENSG00000126254homo_sapiensENSP0000026263397.597.2917sus_scrofaENSSSCP0000003639798.113297.9036
ENSG00000126254homo_sapiensENSP0000026263398.7598.75microcebus_murinusENSMICP0000004999799.371199.3711
ENSG00000126254homo_sapiensENSP0000026263397.597.0833octodon_degusENSODEP0000001859997.095496.6805
ENSG00000126254homo_sapiensENSP0000026263396.2595.8333jaculus_jaculusENSJJAP0000000549097.468497.0464
ENSG00000126254homo_sapiensENSP0000026263397.708397.5ovis_aries_rambouilletENSOARP0002002384898.322998.1132
ENSG00000126254homo_sapiensENSP0000026263397.916797.7083ursus_maritimusENSUMAP0000002783698.532598.3229
ENSG00000126254homo_sapiensENSP0000026263395.208393.9583ochotona_princepsENSOPRP0000000115197.027695.7537
ENSG00000126254homo_sapiensENSP0000026263397.597.2917delphinapterus_leucasENSDLEP0000000357598.113297.9036
ENSG00000126254homo_sapiensENSP0000026263398.12597.9167physeter_catodonENSPCTP0000501474398.742198.5325
ENSG00000126254homo_sapiensENSP0000026263397.291797.0833mus_caroliMGP_CAROLIEiJ_P007875297.698797.4895
ENSG00000126254homo_sapiensENSP0000026263397.291797.0833mus_musculusENSMUSP0000004000597.698797.4895
ENSG00000126254homo_sapiensENSP0000026263396.87596.4583dipodomys_ordiiENSDORP0000001643497.280396.8619
ENSG00000126254homo_sapiensENSP0000026263392.592.2917mustela_putorius_furoENSMPUP0000000623499.107198.8839
ENSG00000126254homo_sapiensENSP0000026263398.541798.3333aotus_nancymaaeENSANAP0000001948499.161498.9518
ENSG00000126254homo_sapiensENSP0000026263384.166784.1667saimiri_boliviensis_boliviensisENSSBOP0000002859393.735593.7355
ENSG00000126254homo_sapiensENSP0000026263351.87551.875vicugna_pacosENSVPAP0000000001964.675364.6753
ENSG00000126254homo_sapiensENSP0000026263393.7593.75chlorocebus_sabaeusENSCSAP0000000076099.778399.7783
ENSG00000126254homo_sapiensENSP0000026263376.458375.8333tupaia_belangeriENSTBEP0000001462482.471981.7978
ENSG00000126254homo_sapiensENSP0000026263397.708397.5phocoena_sinusENSPSNP0000002020598.322998.1132
ENSG00000126254homo_sapiensENSP0000026263398.12597.9167camelus_dromedariusENSCDRP0000500445598.742198.5325
ENSG00000126254homo_sapiensENSP0000026263398.333397.9167carlito_syrichtaENSTSYP0000003495498.744898.3264
ENSG00000126254homo_sapiensENSP0000026263397.916797.7083panthera_tigris_altaicaENSPTIP0000002251298.532598.3229
ENSG00000126254homo_sapiensENSP0000026263397.597.2917rattus_norvegicusENSRNOP0000002972997.90897.6987
ENSG00000126254homo_sapiensENSP0000026263398.7598.75prolemur_simusENSPSMP0000000067899.371199.3711
ENSG00000126254homo_sapiensENSP0000026263396.87596.4583microtus_ochrogasterENSMOCP0000000050697.280396.8619
ENSG00000126254homo_sapiensENSP0000026263387.708387.5sorex_araneusENSSARP0000000968687.708387.5
ENSG00000126254homo_sapiensENSP0000026263397.708397.5peromyscus_maniculatus_bairdiiENSPEMP0000001140798.117297.908
ENSG00000126254homo_sapiensENSP0000026263398.333398.125bos_mutusENSBMUP0000002269398.951898.7421
ENSG00000126254homo_sapiensENSP0000026263397.291797.0833mus_spicilegusENSMSIP0000000748497.698797.4895
ENSG00000126254homo_sapiensENSP0000026263397.083396.6667cricetulus_griseus_chok1gshdENSCGRP0000101894897.489597.0711
ENSG00000126254homo_sapiensENSP0000026263397.916797.7083pteropus_vampyrusENSPVAP0000001208498.532598.3229
ENSG00000126254homo_sapiensENSP0000026263397.596.6667myotis_lucifugusENSMLUP0000001032698.113297.2746
ENSG00000126254homo_sapiensENSP0000026263388.958386.875vombatus_ursinusENSVURP0001003069572.372970.678
ENSG00000126254homo_sapiensENSP0000026263396.458395.625rhinolophus_ferrumequinumENSRFEP0001001520092.785691.984
ENSG00000126254homo_sapiensENSP0000026263388.541785.625neovison_visonENSNVIP0000002277484.830382.0359
ENSG00000126254homo_sapiensENSP0000026263398.333398.125bos_taurusENSBTAP0000006381098.951898.7421
ENSG00000126254homo_sapiensENSP0000026263396.2595heterocephalus_glaber_femaleENSHGLP0000001174596.855395.5975
ENSG00000126254homo_sapiensENSP0000026263399.791799.7917rhinopithecus_bietiENSRBIP0000000166399.791799.7917
ENSG00000126254homo_sapiensENSP0000026263392.708391.4583canis_lupus_dingoENSCAFP0002002370795.085593.8034
ENSG00000126254homo_sapiensENSP0000026263398.541798.5417sciurus_vulgarisENSSVLP0000501222199.161499.1614
ENSG00000126254homo_sapiensENSP0000026263388.7586.875phascolarctos_cinereusENSPCIP0000002070992.207890.2597
ENSG00000126254homo_sapiensENSP0000026263385.208384.1667procavia_capensisENSPCAP0000001218786.105385.0526
ENSG00000126254homo_sapiensENSP0000026263396.458396.0417nannospalax_galiliENSNGAP0000002009496.861996.4435
ENSG00000126254homo_sapiensENSP0000026263398.333398.125bos_grunniensENSBGRP0000003991298.951898.7421
ENSG00000126254homo_sapiensENSP0000026263397.291796.875chinchilla_lanigeraENSCLAP0000001877197.089496.6736
ENSG00000126254homo_sapiensENSP0000026263398.333397.9167cervus_hanglu_yarkandensisENSCHYP0000000984698.951898.5325
ENSG00000126254homo_sapiensENSP0000026263397.291796.875catagonus_wagneriENSCWAP0000000702497.903697.4843
ENSG00000126254homo_sapiensENSP0000026263396.666796.6667ictidomys_tridecemlineatusENSSTOP0000001169198.723498.7234
ENSG00000126254homo_sapiensENSP0000026263398.12597.0833otolemur_garnettiiENSOGAP0000000369798.742197.6939
ENSG00000126254homo_sapiensENSP0000026263397.291796.875cebus_imitatorENSCCAP0000003302997.698797.2803
ENSG00000126254homo_sapiensENSP0000026263396.666796.6667urocitellus_parryiiENSUPAP0001001467898.723498.7234
ENSG00000126254homo_sapiensENSP0000026263398.333398.125moschus_moschiferusENSMMSP0000000297798.951898.7421
ENSG00000126254homo_sapiensENSP0000026263399.166799.1667rhinopithecus_roxellanaENSRROP0000003796299.373799.3737
ENSG00000126254homo_sapiensENSP0000026263397.083397.0833mus_pahariMGP_PahariEiJ_P001562897.489597.4895
ENSG00000126254homo_sapiensENSP0000026263398.7598.75propithecus_coquereliENSPCOP0000002779899.371199.3711
ENSG00000126254homo_sapiensENSP0000026263367.291761.4583laticauda_laticaudataENSLLTP0000002141969.913463.8528
ENSG00000126254homo_sapiensENSP0000026263367.708361.875notechis_scutatusENSNSUP0000002216569.892563.871
ENSG00000126254homo_sapiensENSP0000026263367.916761.875pseudonaja_textilisENSPTXP0000002148870.107563.871
ENSG00000126254homo_sapiensENSP0000026263368.333361.4583anolis_carolinensisENSACAP0000000538372.888965.5556
ENSG00000126254homo_sapiensENSP0000026263368.12562.0833naja_najaENSNNAP0000002332570.474164.2241
ENSG00000126254homo_sapiensENSP0000026263367.561.6667podarcis_muralisENSPMRP0000001208269.230863.2479
ENSG00000126254homo_sapiensENSP0000026263367.708361.25salvator_merianaeENSSMRP0000001496970.652263.913
ENSG00000126254homo_sapiensENSP0000026263367.916761.875gopherus_evgoodeiENSGEVP0000502682670.562864.2857
ENSG00000126254homo_sapiensENSP0000026263367.291759.7917chelonoidis_abingdoniiENSCABP0000002173568.287560.6765
ENSG00000126254homo_sapiensENSP0000026263349.37538.9583takifugu_rubripesENSTRUP0000004947645.315535.7553

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000398involved_in mRNA splicing, via spliceosome1NASHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003729enables mRNA binding1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1NASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1TASHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IEAHomo_sapiens(9606)Component
GO:0046540part_of U4/U6 x U5 tri-snRNP complex1IPIHomo_sapiens(9606)Component
GO:0048025involved_in negative regulation of mRNA splicing, via spliceosome1IEAHomo_sapiens(9606)Process

Expression