RBP Type	Non-canonical_RBPs
Diseases	Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000125450	Gene ID	79902	Accession	8734
Symbol	NUP85	Alias	Nup75;FROUNT;NPHS17	Full Name	nucleoporin 85
Status	Confidence	Length	30100 bases	Strand	Plus strand
Position	17 : 75205659 - 75235758	RNA binding domain	N.A.
Summary	This gene encodes a protein component of the Nup107-160 subunit of the nuclear pore complex. Nuclear pore complexes are embedded in the nuclear envelope and promote bidirectional transport of macromolecules between the cytoplasm and nucleus. The encoded protein can also bind to the C-terminus of chemokine (C-C motif) receptor 2 (CCR2) and promote chemotaxis of monocytes, thereby participating in the inflammatory response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
NUP85-222	ENST00000583569	553	120aa	ENSP00000462487
NUP85-201	ENST00000245544	2133	656aa	ENSP00000245544
NUP85-224	ENST00000583948	1197	No protein	-
NUP85-219	ENST00000582833	453	No protein	-
NUP85-211	ENST00000579324	2010	544aa	ENSP00000463382
NUP85-202	ENST00000449421	1287	No protein	-
NUP85-204	ENST00000577208	572	No protein	-
NUP85-221	ENST00000583548	562	No protein	-
NUP85-210	ENST00000579298	1890	611aa	ENSP00000462749
NUP85-216	ENST00000581104	2233	169aa	ENSP00000461919
NUP85-208	ENST00000578830	922	100aa	ENSP00000462920
NUP85-223	ENST00000583877	575	191aa	ENSP00000463715
NUP85-205	ENST00000577561	524	No protein	-
NUP85-212	ENST00000579557	817	272aa	ENSP00000463496
NUP85-206	ENST00000577645	869	No protein	-
NUP85-220	ENST00000583070	907	302aa	ENSP00000463542
NUP85-215	ENST00000580879	583	19aa	ENSP00000463377
NUP85-217	ENST00000581335	566	No protein	-
NUP85-203	ENST00000540768	1926	259aa	ENSP00000445855
NUP85-218	ENST00000582681	595	No protein	-
NUP85-207	ENST00000578294	385	No protein	-
NUP85-214	ENST00000579900	528	114aa	ENSP00000463437
NUP85-209	ENST00000578987	388	46aa	ENSP00000464544
NUP85-213	ENST00000579838	373	98aa	ENSP00000462364
NUP85-225	ENST00000584155	300	18aa	ENSP00000464433

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
24904	Waist Circumference	9.2210000E-005	-
24954	Waist Circumference	9.2210000E-005	-

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000776	colocalizes_with kinetochore	1	IDA	Homo_sapiens(9606)	Component
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005635	located_in nuclear envelope	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0005643	part_of nuclear pore	1	NAS	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0005819	located_in spindle	1	IEA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0006406	involved_in mRNA export from nucleus	1	IBA	Homo_sapiens(9606)	Process
GO:0006606	involved_in protein import into nucleus	1	IBA	Homo_sapiens(9606)	Process
GO:0006913	involved_in nucleocytoplasmic transport	1	NAS	Homo_sapiens(9606)	Process
GO:0016020	located_in membrane	1	HDA	Homo_sapiens(9606)	Component
GO:0017056	enables structural constituent of nuclear pore	1	IBA	Homo_sapiens(9606)	Function
GO:0030032	involved_in lamellipodium assembly	1	IEA	Homo_sapiens(9606)	Process
GO:0031080	part_of nuclear pore outer ring	3	IBA,IDA,NAS	Homo_sapiens(9606)	Component
GO:0031965	located_in nuclear membrane	1	IEA	Homo_sapiens(9606)	Component
GO:0045893	involved_in positive regulation of DNA-templated transcription	1	IBA	Homo_sapiens(9606)	Process
GO:0048246	involved_in macrophage chemotaxis	1	IEA	Homo_sapiens(9606)	Process
GO:0072006	involved_in nephron development	1	IMP	Homo_sapiens(9606)	Process