Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions TF
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000122386 Gene ID 7755 Accession 12996
Symbol ZNF205 Alias RhitH;Zfp13;ZNF210 Full Name zinc finger protein 205
Status Confidence Length 7958 bases Strand Plus strand
Position 16 : 3112560 - 3120517 RNA binding domain zf-met
Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II; positive regulation of hydrogen peroxide biosynthetic process; and positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Predicted to be located in mitochondrion and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000219091 zf-met PF12874 0.00033 1
ENSP00000371627 zf-met PF12874 0.00033 1
ENSP00000480401 zf-met PF12874 0.00033 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
ZNF205-202 ENST00000382192 2062 554aa ENSP00000371627
ZNF205-201 ENST00000219091 1968 554aa ENSP00000219091
ZNF205-206 ENST00000620094 2309 554aa ENSP00000480401
ZNF205-204 ENST00000444510 726 118aa ENSP00000394360
ZNF205-203 ENST00000414351 1006 278aa ENSP00000403306
ZNF205-205 ENST00000570935 766 255aa ENSP00000460890

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000122386homo_sapiensENSP0000050752536.494823.7113homo_sapiensENSP0000021909131.949520.7581
ENSG00000122386homo_sapiensENSP0000050699714.46238.03461homo_sapiensENSP0000021909121.119111.7329
ENSG00000122386homo_sapiensENSP0000025221136.80324.7212homo_sapiensENSP0000021909135.740124.0072
ENSG00000122386homo_sapiensENSP0000029245039.957726.8499homo_sapiensENSP0000021909134.115522.9242
ENSG00000122386homo_sapiensENSP0000026133237.771725.8152homo_sapiensENSP0000021909125.090317.148
ENSG00000122386homo_sapiensENSP0000050734731.751221.2766homo_sapiensENSP0000021909135.018123.4657
ENSG00000122386homo_sapiensENSP0000035980229.019620.5882homo_sapiensENSP0000021909126.714818.9531
ENSG00000122386homo_sapiensENSP0000049941529.422719.5531homo_sapiensENSP0000021909128.519918.9531
ENSG00000122386homo_sapiensENSP0000037770834.926524.8162homo_sapiensENSP0000021909134.29624.3682
ENSG00000122386homo_sapiensENSP0000032196329.792119.6305homo_sapiensENSP0000021909123.285215.343
ENSG00000122386homo_sapiensENSP0000025220740.101525.8883homo_sapiensENSP0000021909128.519918.4116
ENSG00000122386homo_sapiensENSP0000038008733.551223.9651homo_sapiensENSP0000021909127.797819.8556
ENSG00000122386homo_sapiensENSP0000045558528.224617.7542homo_sapiensENSP0000021909133.57421.1191
ENSG00000122386homo_sapiensENSP0000033157735.018726.03homo_sapiensENSP0000021909133.754525.0903
ENSG00000122386homo_sapiensENSP0000028978840.61726.2211homo_sapiensENSP0000021909128.519918.4116
ENSG00000122386homo_sapiensENSP0000033736332.263822.9947homo_sapiensENSP0000021909132.671523.2852
ENSG00000122386homo_sapiensENSP0000034533941.871929.3103homo_sapiensENSP0000021909130.685921.4801
ENSG00000122386homo_sapiensENSP0000051530040.181332.0242homo_sapiensENSP0000021909124.007219.1336
ENSG00000122386homo_sapiensENSP0000021906927.525618.8873homo_sapiensENSP0000021909133.93523.2852
ENSG00000122386homo_sapiensENSP0000033958530.69522.973homo_sapiensENSP0000021909128.700421.4801
ENSG00000122386homo_sapiensENSP0000033243333.808624.0326homo_sapiensENSP0000021909129.963921.2996
ENSG00000122386homo_sapiensENSP0000032973839.676127.9352homo_sapiensENSP0000021909135.379124.9097
ENSG00000122386homo_sapiensENSP0000046650034.328420.8955homo_sapiensENSP0000021909120.758112.6354
ENSG00000122386homo_sapiensENSP0000021947833.958323.5417homo_sapiensENSP0000021909129.422420.3971
ENSG00000122386homo_sapiensENSP0000036650935.963323.4862homo_sapiensENSP0000021909135.379123.1047
ENSG00000122386homo_sapiensENSP0000027831925.145115.6673homo_sapiensENSP0000021909123.465714.6209
ENSG00000122386homo_sapiensENSP0000036652737.643724.4253homo_sapiensENSP0000021909123.646215.343
ENSG00000122386homo_sapiensENSP0000032314832.326822.3801homo_sapiensENSP0000021909132.85222.7437
ENSG00000122386homo_sapiensENSP0000048170734.864321.9207homo_sapiensENSP0000021909130.144418.9531
ENSG00000122386homo_sapiensENSP0000033275033.9123.3564homo_sapiensENSP0000021909135.379124.3682
ENSG00000122386homo_sapiensENSP0000025007634.909923.8739homo_sapiensENSP0000021909127.978319.1336

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000122386homo_sapiensENSP0000021909196.931495.6679nomascus_leucogenysENSNLEP0000001168197.282696.0145
ENSG00000122386homo_sapiensENSP0000021909199.097598.917pan_paniscusENSPPAP0000001301199.097598.917
ENSG00000122386homo_sapiensENSP0000021909197.472996.9314pongo_abeliiENSPPYP0000000795597.472996.9314
ENSG00000122386homo_sapiensENSP0000021909199.27898.917pan_troglodytesENSPTRP0000001312799.27898.917
ENSG00000122386homo_sapiensENSP0000021909199.27898.917pan_troglodytesENSPTRP0000007446199.27898.917
ENSG00000122386homo_sapiensENSP0000021909199.27898.7365gorilla_gorillaENSGGOP0000001174099.27898.7365
ENSG00000122386homo_sapiensENSP0000021909167.50958.3032ornithorhynchus_anatinusENSOANP0000003737669.003759.5941
ENSG00000122386homo_sapiensENSP0000021909159.025353.0686notamacropus_eugeniiENSMEUP0000000395264.624558.1028
ENSG00000122386homo_sapiensENSP0000021909181.407975.8123dasypus_novemcinctusENSDNOP0000002303581.261375.6757
ENSG00000122386homo_sapiensENSP0000021909163.718459.0253erinaceus_europaeusENSEEUP0000000914782.863976.7606
ENSG00000122386homo_sapiensENSP0000021909148.014441.5162echinops_telfairiENSETEP0000000929169.816360.3675
ENSG00000122386homo_sapiensENSP0000021909169.314164.2599echinops_telfairiENSETEP0000000201569.565264.4928
ENSG00000122386homo_sapiensENSP0000021909192.418890.4332callithrix_jacchusENSCJAP0000006431892.252390.2703
ENSG00000122386homo_sapiensENSP0000021909195.126493.6823cercocebus_atysENSCATP0000001470394.95593.5135
ENSG00000122386homo_sapiensENSP0000021909187.545185.3791macaca_fascicularisENSMFAP0000001593090.654288.4112
ENSG00000122386homo_sapiensENSP0000021909196.028994.5848macaca_mulattaENSMMUP0000001241295.855994.4144
ENSG00000122386homo_sapiensENSP0000021909195.306993.8628macaca_nemestrinaENSMNEP0000002419595.135193.6937
ENSG00000122386homo_sapiensENSP0000021909195.667994.2238papio_anubisENSPANP0000003541995.495594.0541
ENSG00000122386homo_sapiensENSP0000021909196.209494.7653mandrillus_leucophaeusENSMLEP0000001026796.03694.5946
ENSG00000122386homo_sapiensENSP0000021909164.440462.4549tursiops_truncatusENSTTRP0000000381064.673962.6812
ENSG00000122386homo_sapiensENSP0000021909184.29679.4224vulpes_vulpesENSVVUP0000001126484.75579.8548
ENSG00000122386homo_sapiensENSP0000021909175.451370.0361mus_spretusMGP_SPRETEiJ_P004482381.640675.7812
ENSG00000122386homo_sapiensENSP0000021909184.29678.7004equus_asinusENSEASP0000505359176.307271.2418
ENSG00000122386homo_sapiensENSP0000021909183.57477.0758capra_hircusENSCHIP0000002695183.876877.3551
ENSG00000122386homo_sapiensENSP0000021909163.537954.8736loxodonta_africanaENSLAFP0000002334666.165457.1429
ENSG00000122386homo_sapiensENSP0000021909183.393579.6029panthera_leoENSPLOP0000003100183.695779.8913
ENSG00000122386homo_sapiensENSP0000021909185.559680.8664ailuropoda_melanoleucaENSAMEP0000002752768.299764.5533
ENSG00000122386homo_sapiensENSP0000021909183.57477.7978bos_indicus_hybridENSBIXP0000502891684.181878.3636
ENSG00000122386homo_sapiensENSP0000021909180.866475.2708oryctolagus_cuniculusENSOCUP0000000909682.504676.7956
ENSG00000122386homo_sapiensENSP0000021909184.115578.7004equus_caballusENSECAP0000006495376.143871.2418
ENSG00000122386homo_sapiensENSP0000021909184.29679.2419canis_lupus_familiarisENSCAFP0084500413984.909179.8182
ENSG00000122386homo_sapiensENSP0000021909183.393579.6029panthera_pardusENSPPRP0000002304183.695779.8913
ENSG00000122386homo_sapiensENSP0000021909179.061472.9242marmota_marmota_marmotaENSMMMP0000000892386.732780
ENSG00000122386homo_sapiensENSP0000021909185.740180.5054balaenoptera_musculusENSBMSP0001001758385.740180.5054
ENSG00000122386homo_sapiensENSP0000021909180.685974.0072cavia_porcellusENSCPOP0000001827482.169175.3676
ENSG00000122386homo_sapiensENSP0000021909183.57479.7834felis_catusENSFCAP0000004437084.02980.2178
ENSG00000122386homo_sapiensENSP0000021909186.462182.13ursus_americanusENSUAMP0000000952586.462182.13
ENSG00000122386homo_sapiensENSP0000021909152.346646.5704monodelphis_domesticaENSMODP0000005771260.291153.6383
ENSG00000122386homo_sapiensENSP0000021909182.85276.5343bison_bison_bisonENSBBBP0000001482583.759177.3723
ENSG00000122386homo_sapiensENSP0000021909184.837579.6029monodon_monocerosENSMMNP0001501114385.454580.1818
ENSG00000122386homo_sapiensENSP0000021909183.93578.1588sus_scrofaENSSSCP0000002356581.578975.9649
ENSG00000122386homo_sapiensENSP0000021909188.989285.1986microcebus_murinusENSMICP0000000827389.150185.3526
ENSG00000122386homo_sapiensENSP0000021909177.617371.1191octodon_degusENSODEP0000001778883.172176.2089
ENSG00000122386homo_sapiensENSP0000021909175.270870.7581jaculus_jaculusENSJJAP0000001440681.925377.0138
ENSG00000122386homo_sapiensENSP0000021909178.519973.1047ovis_aries_rambouilletENSOARP0002003452085.461779.5678
ENSG00000122386homo_sapiensENSP0000021909185.559681.4079ursus_maritimusENSUMAP0000000089083.893879.823
ENSG00000122386homo_sapiensENSP0000021909178.880973.2852ochotona_princepsENSOPRP0000000534883.716577.7778
ENSG00000122386homo_sapiensENSP0000021909185.018179.7834delphinapterus_leucasENSDLEP0000001979685.636480.3636
ENSG00000122386homo_sapiensENSP0000021909185.018179.7834physeter_catodonENSPCTP0000502957885.171879.9277
ENSG00000122386homo_sapiensENSP0000021909174.909769.4946mus_caroliMGP_CAROLIEiJ_P004292181.054775.1953
ENSG00000122386homo_sapiensENSP0000021909175.451369.6751mus_musculusENSMUSP0000011117881.640675.3906
ENSG00000122386homo_sapiensENSP0000021909167.50962.4549dipodomys_ordiiENSDORP0000001855481.12875.0542
ENSG00000122386homo_sapiensENSP0000021909179.061473.2852mustela_putorius_furoENSMPUP0000001507580.219874.359
ENSG00000122386homo_sapiensENSP0000021909188.628286.6426aotus_nancymaaeENSANAP0000001794392.46790.3955
ENSG00000122386homo_sapiensENSP0000021909192.599390.6137saimiri_boliviensis_boliviensisENSSBOP0000002082192.432490.4504
ENSG00000122386homo_sapiensENSP0000021909196.028993.8628chlorocebus_sabaeusENSCSAP0000000637395.855993.6937
ENSG00000122386homo_sapiensENSP0000021909175.090369.3141mesocricetus_auratusENSMAUP0000001091382.213475.8893
ENSG00000122386homo_sapiensENSP0000021909185.018179.7834phocoena_sinusENSPSNP0000000641585.636480.3636
ENSG00000122386homo_sapiensENSP0000021909183.57478.7004camelus_dromedariusENSCDRP0000502712784.643579.7075
ENSG00000122386homo_sapiensENSP0000021909163.898962.4549carlito_syrichtaENSTSYP0000002685781.379379.5402
ENSG00000122386homo_sapiensENSP0000021909179.963973.2852rattus_norvegicusENSRNOP0000009352182.34275.4647
ENSG00000122386homo_sapiensENSP0000021909187.184184.296prolemur_simusENSPSMP0000002448887.341884.4485
ENSG00000122386homo_sapiensENSP0000021909175.270869.3141microtus_ochrogasterENSMOCP0000001661181.128474.7082
ENSG00000122386homo_sapiensENSP0000021909157.581254.6931sorex_araneusENSSARP0000000593777.615673.7226
ENSG00000122386homo_sapiensENSP0000021909175.812371.6607peromyscus_maniculatus_bairdiiENSPEMP0000001912581.553477.0874
ENSG00000122386homo_sapiensENSP0000021909182.1375.8123bos_mutusENSBMUP0000001863176.342370.4698
ENSG00000122386homo_sapiensENSP0000021909178.880972.7437mus_spicilegusENSMSIP0000001640279.310373.1397
ENSG00000122386homo_sapiensENSP0000021909174.909770.2166cricetulus_griseus_chok1gshdENSCGRP0000102392081.692976.5748
ENSG00000122386homo_sapiensENSP0000021909183.57479.9639pteropus_vampyrusENSPVAP0000000138885.582381.8854
ENSG00000122386homo_sapiensENSP0000021909163.718453.7906myotis_lucifugusENSMLUP0000000001364.770654.6789
ENSG00000122386homo_sapiensENSP0000021909155.234750.5415myotis_lucifugusENSMLUP0000000001275.184368.7961
ENSG00000122386homo_sapiensENSP0000021909162.996454.6931vombatus_ursinusENSVURP0001000030471.079461.7108
ENSG00000122386homo_sapiensENSP0000021909184.65779.4224rhinolophus_ferrumequinumENSRFEP0001002485086.531481.1808
ENSG00000122386homo_sapiensENSP0000021909182.49177.2563neovison_visonENSNVIP0000003028284.162178.8214
ENSG00000122386homo_sapiensENSP0000021909183.57477.7978bos_taurusENSBTAP0000006763884.181878.3636
ENSG00000122386homo_sapiensENSP0000021909183.93577.7978heterocephalus_glaber_femaleENSHGLP0000001127683.184377.102
ENSG00000122386homo_sapiensENSP0000021909195.487493.6823rhinopithecus_bietiENSRBIP0000004282295.487493.6823
ENSG00000122386homo_sapiensENSP0000021909184.29679.2419canis_lupus_dingoENSCAFP0002003330084.909179.8182
ENSG00000122386homo_sapiensENSP0000021909183.754578.5199sciurus_vulgarisENSSVLP0000503286084.517379.235
ENSG00000122386homo_sapiensENSP0000021909172.743763.1769procavia_capensisENSPCAP0000001508175.468265.5431
ENSG00000122386homo_sapiensENSP0000021909171.660764.2599procavia_capensisENSPCAP0000001501772.977965.4412
ENSG00000122386homo_sapiensENSP0000021909176.353871.1191nannospalax_galiliENSNGAP0000001701282.778977.1037
ENSG00000122386homo_sapiensENSP0000021909183.032576.5343bos_grunniensENSBGRP0000003819756.930752.4752
ENSG00000122386homo_sapiensENSP0000021909181.588475.0903chinchilla_lanigeraENSCLAP0000002287681.588475.0903
ENSG00000122386homo_sapiensENSP0000021909184.115577.7978cervus_hanglu_yarkandensisENSCHYP0000000208084.881678.5064
ENSG00000122386homo_sapiensENSP0000021909180.866475.6318catagonus_wagneriENSCWAP0000000823082.656877.3063
ENSG00000122386homo_sapiensENSP0000021909184.115577.7978ictidomys_tridecemlineatusENSSTOP0000000340385.819579.3738
ENSG00000122386homo_sapiensENSP0000021909185.920680.3249otolemur_garnettiiENSOGAP0000000327985.765880.1802
ENSG00000122386homo_sapiensENSP0000021909193.862891.3357cebus_imitatorENSCCAP0000003035593.1990.681
ENSG00000122386homo_sapiensENSP0000021909178.519972.7437urocitellus_parryiiENSUPAP0001002342386.138679.802
ENSG00000122386homo_sapiensENSP0000021909181.76975.0903moschus_moschiferusENSMMSP0000001242380.60574.0214
ENSG00000122386homo_sapiensENSP0000021909195.487493.6823rhinopithecus_roxellanaENSRROP0000000454595.487493.6823
ENSG00000122386homo_sapiensENSP0000021909175.270869.3141mus_pahariMGP_PahariEiJ_P005521481.286674.8538
ENSG00000122386homo_sapiensENSP0000021909187.725684.296propithecus_coquereliENSPCOP0000001424288.043584.6014

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000122involved_in negative regulation of transcription by RNA polymerase II1IMPHomo_sapiens(9606)Process
GO:0000978enables RNA polymerase II cis-regulatory region sequence-specific DNA binding1IBAHomo_sapiens(9606)Function
GO:0000981enables DNA-binding transcription factor activity, RNA polymerase II-specific1IBAHomo_sapiens(9606)Function
GO:0001227enables DNA-binding transcription repressor activity, RNA polymerase II-specific1IEAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IEAHomo_sapiens(9606)Component
GO:0005739located_in mitochondrion1IEAHomo_sapiens(9606)Component
GO:0006355involved_in regulation of DNA-templated transcription1NASHomo_sapiens(9606)Process
GO:0006357involved_in regulation of transcription by RNA polymerase II1IBAHomo_sapiens(9606)Process
GO:0008270enables zinc ion binding1NASHomo_sapiens(9606)Function
GO:0010729involved_in positive regulation of hydrogen peroxide biosynthetic process1IMPHomo_sapiens(9606)Process
GO:1901030involved_in positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway1IMPHomo_sapiens(9606)Process

Expression