RBPWorld - a comprehensive database of RNA Binding Proteins

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Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	E3 ligase
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000119599	Gene ID	26094	Accession	20229
Symbol	DCAF4	Alias	WDR21;WDR21A	Full Name	DDB1 and CUL4 associated factor 4
Status	Confidence	Length	33327 bases	Strand	Plus strand
Position	14 : 72926377 - 72959703	RNA binding domain	N.A.
Summary	This gene encodes a WD repeat-containing protein that interacts with the Cul4-Ddb1 E3 ligase macromolecular complex. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2009]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
DCAF4-202	ENST00000358377	2474	495aa	ENSP00000351147
DCAF4-201	ENST00000353777	1940	325aa	ENSP00000345176
DCAF4-207	ENST00000509320	1872	74aa	ENSP00000422270
DCAF4-203	ENST00000394234	2360	395aa	ENSP00000377781
DCAF4-206	ENST00000509153	1521	435aa	ENSP00000426178
DCAF4-213	ENST00000555042	2374	489aa	ENSP00000452131
DCAF4-210	ENST00000514191	553	No protein	-
DCAF4-204	ENST00000505361	560	No protein	-
DCAF4-208	ENST00000510612	580	No protein	-
DCAF4-205	ENST00000508412	544	No protein	-
DCAF4-211	ENST00000514486	560	No protein	-
DCAF4-212	ENST00000553457	2896	333aa	ENSP00000451186
DCAF4-209	ENST00000513337	565	No protein	-
DCAF4-215	ENST00000557203	524	No protein	-
DCAF4-214	ENST00000555992	579	No protein	-

Gene Model

Click here to download ENSG00000119599's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000119599's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005654	located_in nucleoplasm	1	TAS	Homo_sapiens(9606)	Component
GO:0016567	involved_in protein ubiquitination	1	IEA	Homo_sapiens(9606)	Process
GO:0080008	part_of Cul4-RING E3 ubiquitin ligase complex	2	IBA,IDA	Homo_sapiens(9606)	Component

Expression