Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000114784 Gene ID 10289 Accession 30792
Symbol EIF1B Alias GC20 Full Name eukaryotic translation initiation factor 1B
Status Confidence Length 2718 bases Strand Plus strand
Position 3 : 40309707 - 40312424 RNA binding domain SUI1
Summary Enables RNA binding activity. Predicted to be involved in translational initiation. Predicted to be part of eukaryotic 43S preinitiation complex. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000232905 SUI1 PF01253 4.2e-29 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
EIF1B-201 ENST00000232905 987 113aa ENSP00000232905
EIF1B-202 ENST00000462088 873 No protein -
EIF1B-204 ENST00000488260 637 No protein -
EIF1B-203 ENST00000487151 632 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000114784homo_sapiensENSP0000041944997.345192.0354homo_sapiensENSP0000023290597.345192.0354

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000114784homo_sapiensENSP00000232905100100nomascus_leucogenysENSNLEP00000006860100100
ENSG00000114784homo_sapiensENSP00000232905100100pan_paniscusENSPPAP00000009704100100
ENSG00000114784homo_sapiensENSP00000232905100100pongo_abeliiENSPPYP00000042325100100
ENSG00000114784homo_sapiensENSP00000232905100100pan_troglodytesENSPTRP00000025478100100
ENSG00000114784homo_sapiensENSP00000232905100100gorilla_gorillaENSGGOP00000008119100100
ENSG00000114784homo_sapiensENSP0000023290593.805392.9204ornithorhynchus_anatinusENSOANP0000004928392.982592.1053
ENSG00000114784homo_sapiensENSP00000232905100100sarcophilus_harrisiiENSSHAP00000028883100100
ENSG00000114784homo_sapiensENSP0000023290598.230196.4602notamacropus_eugeniiENSMEUP0000000487499.107197.3214
ENSG00000114784homo_sapiensENSP0000023290554.867354.8673notamacropus_eugeniiENSMEUP00000007215100100
ENSG00000114784homo_sapiensENSP0000023290589.380588.4956choloepus_hoffmanniENSCHOP0000000844999.019698.0392
ENSG00000114784homo_sapiensENSP0000023290550.442549.5575erinaceus_europaeusENSEEUP0000001141250.442549.5575
ENSG00000114784homo_sapiensENSP00000232905100100echinops_telfairiENSETEP00000014044100100
ENSG00000114784homo_sapiensENSP00000232905100100callithrix_jacchusENSCJAP00000064087100100
ENSG00000114784homo_sapiensENSP00000232905100100cercocebus_atysENSCATP00000004913100100
ENSG00000114784homo_sapiensENSP00000232905100100macaca_fascicularisENSMFAP00000000785100100
ENSG00000114784homo_sapiensENSP00000232905100100macaca_mulattaENSMMUP00000066694100100
ENSG00000114784homo_sapiensENSP00000232905100100macaca_nemestrinaENSMNEP00000017594100100
ENSG00000114784homo_sapiensENSP00000232905100100papio_anubisENSPANP00000036025100100
ENSG00000114784homo_sapiensENSP00000232905100100mandrillus_leucophaeusENSMLEP00000018326100100
ENSG00000114784homo_sapiensENSP00000232905100100tursiops_truncatusENSTTRP00000000154100100
ENSG00000114784homo_sapiensENSP00000232905100100vulpes_vulpesENSVVUP00000007328100100
ENSG00000114784homo_sapiensENSP00000232905100100mus_spretusMGP_SPRETEiJ_P0094343100100
ENSG00000114784homo_sapiensENSP00000232905100100equus_asinusENSEASP00005010772100100
ENSG00000114784homo_sapiensENSP0000023290566.371761.0619capra_hircusENSCHIP0000002582491.463484.1463
ENSG00000114784homo_sapiensENSP00000232905100100loxodonta_africanaENSLAFP00000000961100100
ENSG00000114784homo_sapiensENSP00000232905100100panthera_leoENSPLOP00000019829100100
ENSG00000114784homo_sapiensENSP00000232905100100ailuropoda_melanoleucaENSAMEP00000034567100100
ENSG00000114784homo_sapiensENSP00000232905100100bos_indicus_hybridENSBIXP00005021548100100
ENSG00000114784homo_sapiensENSP00000232905100100equus_caballusENSECAP00000004015100100
ENSG00000114784homo_sapiensENSP00000232905100100canis_lupus_familiarisENSCAFP00845023449100100
ENSG00000114784homo_sapiensENSP0000023290599.11599.115panthera_pardusENSPPRP0000000953899.11599.115
ENSG00000114784homo_sapiensENSP0000023290596.460293.8053marmota_marmota_marmotaENSMMMP0000001100483.846281.5385
ENSG00000114784homo_sapiensENSP00000232905100100balaenoptera_musculusENSBMSP00010021187100100
ENSG00000114784homo_sapiensENSP00000232905100100cavia_porcellusENSCPOP00000023773100100
ENSG00000114784homo_sapiensENSP00000232905100100felis_catusENSFCAP00000003002100100
ENSG00000114784homo_sapiensENSP0000023290590.265590.2655ursus_americanusENSUAMP0000002894093.57893.578
ENSG00000114784homo_sapiensENSP00000232905100100monodelphis_domesticaENSMODP00000002974100100
ENSG00000114784homo_sapiensENSP00000232905100100bison_bison_bisonENSBBBP00000025979100100
ENSG00000114784homo_sapiensENSP00000232905100100monodon_monocerosENSMMNP00015026090100100
ENSG00000114784homo_sapiensENSP00000232905100100sus_scrofaENSSSCP00000012016100100
ENSG00000114784homo_sapiensENSP00000232905100100microcebus_murinusENSMICP00000051421100100
ENSG00000114784homo_sapiensENSP00000232905100100octodon_degusENSODEP00000014725100100
ENSG00000114784homo_sapiensENSP0000023290588.495688.4956jaculus_jaculusENSJJAP0000001948498.039298.0392
ENSG00000114784homo_sapiensENSP00000232905100100ovis_aries_rambouilletENSOARP00020023720100100
ENSG00000114784homo_sapiensENSP0000023290595.575290.2655ursus_maritimusENSUMAP000000057769085
ENSG00000114784homo_sapiensENSP0000023290589.380586.7257ochotona_princepsENSOPRP0000000144092.660689.9083
ENSG00000114784homo_sapiensENSP00000232905100100delphinapterus_leucasENSDLEP00000013871100100
ENSG00000114784homo_sapiensENSP00000232905100100physeter_catodonENSPCTP00005025378100100
ENSG00000114784homo_sapiensENSP00000232905100100mus_caroliMGP_CAROLIEiJ_P0090597100100
ENSG00000114784homo_sapiensENSP00000232905100100mus_musculusENSMUSP00000007139100100
ENSG00000114784homo_sapiensENSP0000023290591.150491.1504dipodomys_ordiiENSDORP00000020748100100
ENSG00000114784homo_sapiensENSP00000232905100100mustela_putorius_furoENSMPUP00000017847100100
ENSG00000114784homo_sapiensENSP00000232905100100aotus_nancymaaeENSANAP00000018283100100
ENSG00000114784homo_sapiensENSP0000023290595.575293.8053saimiri_boliviensis_boliviensisENSSBOP0000001435880.59779.1045
ENSG00000114784homo_sapiensENSP00000232905100100vicugna_pacosENSVPAP00000000892100100
ENSG00000114784homo_sapiensENSP00000232905100100chlorocebus_sabaeusENSCSAP00000012964100100
ENSG00000114784homo_sapiensENSP0000023290510098.2301tupaia_belangeriENSTBEP0000001141310098.2301
ENSG00000114784homo_sapiensENSP00000232905100100mesocricetus_auratusENSMAUP00000018149100100
ENSG00000114784homo_sapiensENSP00000232905100100phocoena_sinusENSPSNP00000015355100100
ENSG00000114784homo_sapiensENSP00000232905100100camelus_dromedariusENSCDRP00005029188100100
ENSG00000114784homo_sapiensENSP00000232905100100carlito_syrichtaENSTSYP00000005804100100
ENSG00000114784homo_sapiensENSP0000023290593.805391.1504panthera_tigris_altaicaENSPTIP0000001411778.518576.2963
ENSG00000114784homo_sapiensENSP0000023290591.150490.2655rattus_norvegicusENSRNOP0000002561565.189964.557
ENSG00000114784homo_sapiensENSP00000232905100100prolemur_simusENSPSMP00000032810100100
ENSG00000114784homo_sapiensENSP0000023290510099.115microtus_ochrogasterENSMOCP0000001984199.122898.2456
ENSG00000114784homo_sapiensENSP00000232905100100peromyscus_maniculatus_bairdiiENSPEMP00000016479100100
ENSG00000114784homo_sapiensENSP00000232905100100bos_mutusENSBMUP00000021280100100
ENSG00000114784homo_sapiensENSP0000023290586.725781.4159mus_spicilegusENSMSIP0000003158763.636459.7403
ENSG00000114784homo_sapiensENSP00000232905100100cricetulus_griseus_chok1gshdENSCGRP00001003938100100
ENSG00000114784homo_sapiensENSP00000232905100100pteropus_vampyrusENSPVAP00000013117100100
ENSG00000114784homo_sapiensENSP00000232905100100myotis_lucifugusENSMLUP00000013119100100
ENSG00000114784homo_sapiensENSP0000023290591.150484.9557vombatus_ursinusENSVURP0001000793991.150484.9557
ENSG00000114784homo_sapiensENSP0000023290593.805389.3805vombatus_ursinusENSVURP0001000340893.805389.3805
ENSG00000114784homo_sapiensENSP00000232905100100vombatus_ursinusENSVURP00010028268100100
ENSG00000114784homo_sapiensENSP00000232905100100rhinolophus_ferrumequinumENSRFEP00010024982100100
ENSG00000114784homo_sapiensENSP00000232905100100neovison_visonENSNVIP00000031738100100
ENSG00000114784homo_sapiensENSP00000232905100100bos_taurusENSBTAP00000025437100100
ENSG00000114784homo_sapiensENSP00000232905100100heterocephalus_glaber_femaleENSHGLP00000055105100100
ENSG00000114784homo_sapiensENSP00000232905100100rhinopithecus_bietiENSRBIP00000001404100100
ENSG00000114784homo_sapiensENSP00000232905100100canis_lupus_dingoENSCAFP00020032829100100
ENSG00000114784homo_sapiensENSP00000232905100100sciurus_vulgarisENSSVLP00005027424100100
ENSG00000114784homo_sapiensENSP00000232905100100phascolarctos_cinereusENSPCIP00000021580100100
ENSG00000114784homo_sapiensENSP0000023290591.150491.1504procavia_capensisENSPCAP0000001456499.038599.0385
ENSG00000114784homo_sapiensENSP00000232905100100nannospalax_galiliENSNGAP00000004772100100
ENSG00000114784homo_sapiensENSP00000232905100100bos_grunniensENSBGRP00000034695100100
ENSG00000114784homo_sapiensENSP0000023290590.265590.2655chinchilla_lanigeraENSCLAP00000023386100100
ENSG00000114784homo_sapiensENSP00000232905100100cervus_hanglu_yarkandensisENSCHYP00000039196100100
ENSG00000114784homo_sapiensENSP00000232905100100catagonus_wagneriENSCWAP00000016971100100
ENSG00000114784homo_sapiensENSP00000232905100100ictidomys_tridecemlineatusENSSTOP00000010904100100
ENSG00000114784homo_sapiensENSP00000232905100100otolemur_garnettiiENSOGAP00000021967100100
ENSG00000114784homo_sapiensENSP00000232905100100cebus_imitatorENSCCAP00000026596100100
ENSG00000114784homo_sapiensENSP00000232905100100urocitellus_parryiiENSUPAP00010013607100100
ENSG00000114784homo_sapiensENSP00000232905100100moschus_moschiferusENSMMSP00000029348100100
ENSG00000114784homo_sapiensENSP00000232905100100rhinopithecus_roxellanaENSRROP00000033352100100
ENSG00000114784homo_sapiensENSP00000232905100100mus_pahariMGP_PahariEiJ_P0026276100100
ENSG00000114784homo_sapiensENSP00000232905100100propithecus_coquereliENSPCOP00000017111100100
ENSG00000114784homo_sapiensENSP0000023290567.256650.4425caenorhabditis_elegansT27F7.3.169.724852.2936
ENSG00000114784homo_sapiensENSP0000023290592.035484.9557callorhinchus_miliiENSCMIP0000000114575.362369.5652
ENSG00000114784homo_sapiensENSP0000023290598.230196.4602latimeria_chalumnaeENSLACP0000000451298.230196.4602
ENSG00000114784homo_sapiensENSP0000023290598.230197.3451lepisosteus_oculatusENSLOCP0000001593587.401686.6142
ENSG00000114784homo_sapiensENSP0000023290597.345193.8053clupea_harengusENSCHAP0000004716097.345193.8053
ENSG00000114784homo_sapiensENSP0000023290597.345196.4602danio_rerioENSDARP0000012062497.345196.4602
ENSG00000114784homo_sapiensENSP0000023290590.265586.7257carassius_auratusENSCARP0000010797178.461575.3846
ENSG00000114784homo_sapiensENSP0000023290592.035488.4956carassius_auratusENSCARP0000004527180.620277.5194
ENSG00000114784homo_sapiensENSP0000023290597.345194.6903carassius_auratusENSCARP0000011385197.345194.6903
ENSG00000114784homo_sapiensENSP0000023290598.230195.5752astyanax_mexicanusENSAMXP0000002811598.230195.5752
ENSG00000114784homo_sapiensENSP0000023290580.53171.6814ictalurus_punctatusENSIPUP0000001855986.666777.1429
ENSG00000114784homo_sapiensENSP0000023290598.230192.9204esox_luciusENSELUP0000000121398.230192.9204
ENSG00000114784homo_sapiensENSP0000023290597.345195.5752electrophorus_electricusENSEEEP0000002022097.345195.5752
ENSG00000114784homo_sapiensENSP0000023290598.230194.6903oncorhynchus_kisutchENSOKIP0000508728998.230194.6903
ENSG00000114784homo_sapiensENSP0000023290598.230194.6903oncorhynchus_mykissENSOMYP0000013512698.230194.6903
ENSG00000114784homo_sapiensENSP0000023290598.230194.6903salmo_salarENSSSAP0000008893990.983687.7049
ENSG00000114784homo_sapiensENSP0000023290598.230194.6903salmo_truttaENSSTUP0000001876198.230194.6903
ENSG00000114784homo_sapiensENSP0000023290591.150484.9557gadus_morhuaENSGMOP0000002383270.06865.3061
ENSG00000114784homo_sapiensENSP0000023290566.371761.0619oreochromis_niloticusENSONIP0000006507655.147150.7353
ENSG00000114784homo_sapiensENSP0000023290599.11596.4602xenopus_tropicalisENSXETP0000010097199.11596.4602
ENSG00000114784homo_sapiensENSP00000232905100100chrysemys_picta_belliiENSCPBP00000000104100100
ENSG00000114784homo_sapiensENSP0000023290510099.115sphenodon_punctatusENSSPUP0000000307610099.115
ENSG00000114784homo_sapiensENSP0000023290595.575292.9204crocodylus_porosusENSCPRP0000501219991.525488.983
ENSG00000114784homo_sapiensENSP0000023290551.327449.5575laticauda_laticaudataENSLLTP0000001520484.05881.1594
ENSG00000114784homo_sapiensENSP0000023290592.035492.0354notechis_scutatusENSNSUP0000001029895.412895.4128
ENSG00000114784homo_sapiensENSP0000023290592.035492.0354pseudonaja_textilisENSPTXP0000001971195.412895.4128
ENSG00000114784homo_sapiensENSP0000023290510098.2301anas_platyrhynchos_platyrhynchosENSAPLP0000000063210098.2301
ENSG00000114784homo_sapiensENSP0000023290510098.2301gallus_gallusENSGALP0001002302910098.2301
ENSG00000114784homo_sapiensENSP0000023290510098.2301meleagris_gallopavoENSMGAP0000001229447.881447.0339
ENSG00000114784homo_sapiensENSP0000023290510098.2301serinus_canariaENSSCAP0000000230310098.2301
ENSG00000114784homo_sapiensENSP0000023290510098.2301parus_majorENSPMJP0000001388645.244.4
ENSG00000114784homo_sapiensENSP0000023290597.345195.5752anolis_carolinensisENSACAP0000002611088.709787.0968
ENSG00000114784homo_sapiensENSP0000023290596.460293.8053naja_najaENSNNAP0000001589378.985576.8116
ENSG00000114784homo_sapiensENSP0000023290510098.2301podarcis_muralisENSPMRP0000002626663.483162.3596
ENSG00000114784homo_sapiensENSP0000023290596.460292.9204geospiza_fortisENSGFOP0000000146294.782691.3043
ENSG00000114784homo_sapiensENSP0000023290510098.2301taeniopygia_guttataENSTGUP0000003364010098.2301
ENSG00000114784homo_sapiensENSP00000232905100100erpetoichthys_calabaricusENSECRP00000007924100100
ENSG00000114784homo_sapiensENSP00000232905100100salvator_merianaeENSSMRP00000021465100100
ENSG00000114784homo_sapiensENSP0000023290565.486761.9469amphilophus_citrinellusENSACIP0000001231993.670988.6076
ENSG00000114784homo_sapiensENSP0000023290595.575292.9204dicentrarchus_labraxENSDLAP0000508264095.575292.9204
ENSG00000114784homo_sapiensENSP0000023290591.150490.2655pelodiscus_sinensisENSPSIP0000000247899.038598.0769
ENSG00000114784homo_sapiensENSP00000232905100100gopherus_evgoodeiENSGEVP00005007743100100
ENSG00000114784homo_sapiensENSP00000232905100100chelonoidis_abingdoniiENSCABP00000016859100100
ENSG00000114784homo_sapiensENSP0000023290510099.115struthio_camelus_australisENSSCUP0000001894610099.115
ENSG00000114784homo_sapiensENSP0000023290510098.2301anser_brachyrhynchusENSABRP0000001647210098.2301
ENSG00000114784homo_sapiensENSP0000023290510098.2301strigops_habroptilaENSSHBP0000500149110098.2301
ENSG00000114784homo_sapiensENSP00000232905100100terrapene_carolina_triunguisENSTMTP00000017583100100
ENSG00000114784homo_sapiensENSP00000232905100100terrapene_carolina_triunguisENSTMTP00000026836100100
ENSG00000114784homo_sapiensENSP0000023290598.230195.5752pygocentrus_nattereriENSPNAP0000001763198.230195.5752
ENSG00000114784homo_sapiensENSP0000023290583.185879.646oncorhynchus_tshawytschaENSOTSP0000501534565.277862.5
ENSG00000114784homo_sapiensENSP0000023290510098.2301aquila_chrysaetos_chrysaetosENSACCP0002000291910098.2301
ENSG00000114784homo_sapiensENSP0000023290593.805390.2655ficedula_albicollisENSFALP0000001283458.563556.3536
ENSG00000114784homo_sapiensENSP0000023290591.150488.4956cyprinus_carpio_carpioENSCCRP0000004820987.288184.7458
ENSG00000114784homo_sapiensENSP0000023290510098.2301coturnix_japonicaENSCJPP0000500454210098.2301
ENSG00000114784homo_sapiensENSP0000023290597.345194.6903sinocyclocheilus_grahamiENSSGRP0000008875197.345194.6903
ENSG00000114784homo_sapiensENSP0000023290583.185880.531sinocyclocheilus_grahamiENSSGRP0000002881965.734363.6364
ENSG00000114784homo_sapiensENSP0000023290510099.115paramormyrops_kingsleyaeENSPKIP0000001849110099.115
ENSG00000114784homo_sapiensENSP0000023290592.035488.4956scleropages_formosusENSSFOP0001505725271.724168.9655
ENSG00000114784homo_sapiensENSP0000023290596.460292.9204leptobrachium_leishanenseENSLLEP0000003316253.694651.7241

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding2HDA,IBAHomo_sapiens(9606)Function
GO:0003743enables translation initiation factor activity1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005575is_active_in cellular_component1NDHomo_sapiens(9606)Component
GO:0006413involved_in translational initiation1IEAHomo_sapiens(9606)Process
GO:0006446involved_in regulation of translational initiation1NASHomo_sapiens(9606)Process
GO:0016282part_of eukaryotic 43S preinitiation complex1IBAHomo_sapiens(9606)Component
GO:0043024enables ribosomal small subunit binding1IBAHomo_sapiens(9606)Function

Expression