Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions E3 ligase
Localizations N.A.
BulkPerturb-seq

Description

Ensembl ID ENSG00000112343 Gene ID 10475 Accession 10059
Symbol TRIM38 Alias RNF15;RORET Full Name tripartite motif containing 38
Status Confidence Length 28430 bases Strand Plus strand
Position 6 : 25962802 - 25991231 RNA binding domain SPRY
Summary This gene encodes a member of the tripartite motif (TRIM) family. The encoded protein contains a RING-type zinc finger, B box-type zinc finger and SPRY domain. The function of this protein has not been identified. A pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Jul 2012]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000349596 SPRY PF00622 1.3e-17 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
21423624 Hypomethylation of intragenic LINE-1 represses transcription in cancer cells through AGO2. Chatchawit Aporntewan 2011-03-15 PloS one

Transcripts

Name Transcript ID bp Protein Translation ID

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
37326Platelet Function Tests4.1400000E-006-
94405Iron4E-619084217

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000209involved_in protein polyubiquitination1IBAHomo_sapiens(9606)Process
GO:0003713enables transcription coactivator activity1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005575is_active_in cellular_component1NDHomo_sapiens(9606)Component
GO:0005654is_active_in nucleoplasm1IBAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm1IBAHomo_sapiens(9606)Component
GO:0005829is_active_in cytosol2IBA,TASHomo_sapiens(9606)Component
GO:0008270enables zinc ion binding1IEAHomo_sapiens(9606)Function
GO:0010508involved_in positive regulation of autophagy1IBAHomo_sapiens(9606)Process
GO:0016925involved_in protein sumoylation1IEAHomo_sapiens(9606)Process
GO:0019901enables protein kinase binding1IBAHomo_sapiens(9606)Function
GO:0032648involved_in regulation of interferon-beta production1IEAHomo_sapiens(9606)Process
GO:0032880involved_in regulation of protein localization1IBAHomo_sapiens(9606)Process
GO:0042803enables protein homodimerization activity1IBAHomo_sapiens(9606)Function
GO:0043123involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling3HMP,IBA,IDAHomo_sapiens(9606)Process
GO:0043161involved_in proteasome-mediated ubiquitin-dependent protein catabolic process1IEAHomo_sapiens(9606)Process
GO:0045070involved_in positive regulation of viral genome replication1IEAHomo_sapiens(9606)Process
GO:0045087involved_in innate immune response1IBAHomo_sapiens(9606)Process
GO:0045893involved_in positive regulation of DNA-templated transcription1IEAHomo_sapiens(9606)Process
GO:0046596involved_in regulation of viral entry into host cell1IBAHomo_sapiens(9606)Process
GO:0046598involved_in positive regulation of viral entry into host cell1IDAHomo_sapiens(9606)Process
GO:0050687involved_in negative regulation of defense response to virus1IEAHomo_sapiens(9606)Process
GO:0051091involved_in positive regulation of DNA-binding transcription factor activity1IDAHomo_sapiens(9606)Process
GO:0051092involved_in positive regulation of NF-kappaB transcription factor activity2IBA,IDAHomo_sapiens(9606)Process
GO:0061630enables ubiquitin protein ligase activity2IBA,ISSHomo_sapiens(9606)Function
GO:0070936involved_in protein K48-linked ubiquitination1IEAHomo_sapiens(9606)Process

Expression