Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerFlavivirusesSARS-COV-2DengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq DataSet_01_134 DataSet_01_38

Description

Ensembl ID ENSG00000110321 Gene ID 1982 Accession 3297
Symbol EIF4G2 Alias P97;AAG1;DAP5;NAT1 Full Name eukaryotic translation initiation factor 4 gamma 2
Status Confidence Length 11891 bases Strand Minus strand
Position 11 : 10797050 - 10808940 RNA binding domain W2 , MIF4G , MA3
Summary Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000433561 MA3 PF02847 5.1e-18 1
ENSP00000379778 MA3 PF02847 3e-16 1
ENSP00000379778 MIF4G PF02854 4.4e-57 2
ENSP00000379778 W2 PF02020 1.8e-19 3
ENSP00000340281 MA3 PF02847 3.2e-16 1
ENSP00000340281 MIF4G PF02854 4.8e-57 2
ENSP00000340281 W2 PF02020 1.9e-19 3
ENSP00000433371 MA3 PF02847 3.2e-16 1
ENSP00000433371 MIF4G PF02854 4.8e-57 2
ENSP00000433371 W2 PF02020 1.9e-19 3
ENSP00000433664 MA3 PF02847 3.2e-16 1
ENSP00000433664 MIF4G PF02854 4.8e-57 2
ENSP00000433664 W2 PF02020 1.9e-19 3
ENSP00000434815 MA3 PF02847 7.9e-07 1
ENSP00000434815 W2 PF02020 1.1e-10 2
ENSP00000431583 MIF4G PF02854 8.4e-58 1
ENSP00000433121 MIF4G PF02854 2.6e-49 1
ENSP00000435523 MIF4G PF02854 1.1e-36 1
ENSP00000434940 MIF4G PF02854 8.2e-18 1
ENSP00000431511 MIF4G PF02854 5.2e-10 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
37124518 Circular RNAs: pivotal role in the leukemogenesis and novel indicators for the diagnosis and prognosis of acute myeloid leukemia. Atefe Rahmati 2023-01-01 Frontiers in oncology
31010886 eIF4G2 balances its own mRNA translation via a PCBP2-based feedback loop. V Victoria Smirnova 2019-07-01 RNA (New York, N.Y.)
35018467 Ribosomal leaky scanning through a translated uORF requires eIF4G2. V Victoria Smirnova 2022-01-25 Nucleic acids research
28886744 Identification of high-confidence RNA regulatory elements by combinatorial classification of RNA-protein binding sites. Eric Yang Li 2017-09-08 Genome biology
29800452 SMARTIV: combined sequence and structure de-novo motif discovery for in-vivo RNA binding data. Maya Polishchuk 2018-07-02 Nucleic acids research
36517212 Specific mechanisms of translation initiation in higher eukaryotes: the eIF4G2 story. D Ekaterina Shestakova 2023-03-01 RNA (New York, N.Y.)
34559986 ERα is an RNA-binding protein sustaining tumor cell survival and drug resistance. Yichen Xu 2021-09-30 Cell

Transcripts

Name Transcript ID bp Protein Translation ID
EIF4G2-208 ENST00000526148 4001 907aa ENSP00000433664
EIF4G2-205 ENST00000525681 3654 907aa ENSP00000433371
EIF4G2-225 ENST00000532383 6769 No protein -
EIF4G2-206 ENST00000525972 3664 No protein -
EIF4G2-201 ENST00000339995 3794 907aa ENSP00000340281
EIF4G2-202 ENST00000396525 3346 869aa ENSP00000379778
EIF4G2-222 ENST00000532120 223 No protein -
EIF4G2-204 ENST00000525606 690 No protein -
EIF4G2-230 ENST00000534470 520 No protein -
EIF4G2-229 ENST00000534272 591 No protein -
EIF4G2-213 ENST00000528839 702 234aa ENSP00000434815
EIF4G2-217 ENST00000531180 557 185aa ENSP00000433561
EIF4G2-215 ENST00000530564 849 No protein -
EIF4G2-218 ENST00000531416 1969 444aa ENSP00000431583
EIF4G2-220 ENST00000531647 579 84aa ENSP00000433217
EIF4G2-221 ENST00000532082 1069 282aa ENSP00000433121
EIF4G2-224 ENST00000532349 550 No protein -
EIF4G2-203 ENST00000524932 1286 244aa ENSP00000435523
EIF4G2-209 ENST00000527015 582 No protein -
EIF4G2-231 ENST00000534605 198 20aa ENSP00000436680
EIF4G2-223 ENST00000532152 587 No protein -
EIF4G2-210 ENST00000527419 571 88aa ENSP00000434940
EIF4G2-219 ENST00000531507 591 No protein -
EIF4G2-212 ENST00000528562 601 46aa ENSP00000435220
EIF4G2-226 ENST00000532570 573 129aa ENSP00000431511
EIF4G2-214 ENST00000530211 591 116aa ENSP00000433335
EIF4G2-211 ENST00000527526 555 112aa ENSP00000436235
EIF4G2-216 ENST00000530702 563 84aa ENSP00000435912
EIF4G2-207 ENST00000525995 592 No protein -
EIF4G2-227 ENST00000533485 806 No protein -
EIF4G2-228 ENST00000534246 523 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
19735Blood Vessels1.296e-005-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000110321homo_sapiensENSP0000031687925.453416.3852homo_sapiensENSP0000034028144.873228.8864
ENSG00000110321homo_sapiensENSP0000047351024.984816.1487homo_sapiensENSP0000034028145.20429.2172

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000110321homo_sapiensENSP0000034028110099.8897nomascus_leucogenysENSNLEP0000002535192.55192.449
ENSG00000110321homo_sapiensENSP0000034028197.794997.5744pan_paniscusENSPPAP0000001153196.41396.1957
ENSG00000110321homo_sapiensENSP0000034028110099.8897pongo_abeliiENSPPYP0000004347410099.8897
ENSG00000110321homo_sapiensENSP0000034028197.794997.4642pan_troglodytesENSPTRP0000000586996.41396.087
ENSG00000110321homo_sapiensENSP0000034028197.794997.5744gorilla_gorillaENSGGOP0000001266496.41396.1957
ENSG00000110321homo_sapiensENSP0000034028190.84989.1952ornithorhynchus_anatinusENSOANP0000003884987.752986.1555
ENSG00000110321homo_sapiensENSP0000034028199.55998.2359sarcophilus_harrisiiENSSHAP0000003526899.55998.2359
ENSG00000110321homo_sapiensENSP0000034028171.444370.452notamacropus_eugeniiENSMEUP0000000382672.564471.5565
ENSG00000110321homo_sapiensENSP0000034028176.736576.516choloepus_hoffmanniENSCHOP0000001010377.076476.8549
ENSG00000110321homo_sapiensENSP0000034028177.067377.0673dasypus_novemcinctusENSDNOP0000000173199.714799.7147
ENSG00000110321homo_sapiensENSP0000034028189.195288.9746erinaceus_europaeusENSEEUP0000000032910099.7528
ENSG00000110321homo_sapiensENSP0000034028189.746489.4157echinops_telfairiENSETEP0000001469889.746489.4157
ENSG00000110321homo_sapiensENSP0000034028110099.7795callithrix_jacchusENSCJAP0000001989110099.7795
ENSG00000110321homo_sapiensENSP0000034028110099.7795cercocebus_atysENSCATP0000003632492.456792.2528
ENSG00000110321homo_sapiensENSP0000034028110099.7795macaca_fascicularisENSMFAP0000000149095.373395.163
ENSG00000110321homo_sapiensENSP0000034028110099.6692macaca_mulattaENSMMUP0000003696193.601793.2921
ENSG00000110321homo_sapiensENSP0000034028110099.7795macaca_nemestrinaENSMNEP0000002961487.972887.7789
ENSG00000110321homo_sapiensENSP0000034028110099.7795papio_anubisENSPANP0000004092610099.7795
ENSG00000110321homo_sapiensENSP0000034028110099.7795mandrillus_leucophaeusENSMLEP0000002698492.456792.2528
ENSG00000110321homo_sapiensENSP0000034028188.092687.9824tursiops_truncatusENSTTRP0000001332688.482888.3721
ENSG00000110321homo_sapiensENSP0000034028198.566798.4565vulpes_vulpesENSVVUP0000003570498.566798.4565
ENSG00000110321homo_sapiensENSP0000034028199.779598.8975mus_spretusMGP_SPRETEiJ_P008495999.889699.0066
ENSG00000110321homo_sapiensENSP0000034028110099.6692equus_asinusENSEASP0000500810610099.6692
ENSG00000110321homo_sapiensENSP0000034028198.566798.4565capra_hircusENSCHIP0000001866298.784598.674
ENSG00000110321homo_sapiensENSP0000034028199.779599.559loxodonta_africanaENSLAFP0000001071699.779599.559
ENSG00000110321homo_sapiensENSP0000034028110099.7795panthera_leoENSPLOP0000001033010099.7795
ENSG00000110321homo_sapiensENSP0000034028110099.6692ailuropoda_melanoleucaENSAMEP0000001541810099.6692
ENSG00000110321homo_sapiensENSP0000034028110099.8897bos_indicus_hybridENSBIXP0000501102210099.8897
ENSG00000110321homo_sapiensENSP0000034028110099.6692oryctolagus_cuniculusENSOCUP0000004692892.645692.3391
ENSG00000110321homo_sapiensENSP0000034028110099.6692equus_caballusENSECAP0000002517710099.6692
ENSG00000110321homo_sapiensENSP0000034028197.794997.3539canis_lupus_familiarisENSCAFP0084502154888.877888.477
ENSG00000110321homo_sapiensENSP0000034028110099.7795panthera_pardusENSPPRP0000002167410099.7795
ENSG00000110321homo_sapiensENSP0000034028199.889799.4487marmota_marmota_marmotaENSMMMP0000000115699.889799.4487
ENSG00000110321homo_sapiensENSP0000034028162.403560.419balaenoptera_musculusENSBMSP0001002872695.126192.1008
ENSG00000110321homo_sapiensENSP0000034028110099.7795cavia_porcellusENSCPOP0000002950794.775394.5664
ENSG00000110321homo_sapiensENSP0000034028110099.7795felis_catusENSFCAP0000001982810099.7795
ENSG00000110321homo_sapiensENSP0000034028199.889799.6692ursus_americanusENSUAMP0000002819798.692898.4749
ENSG00000110321homo_sapiensENSP0000034028199.669298.3462monodelphis_domesticaENSMODP0000001039699.669298.3462
ENSG00000110321homo_sapiensENSP0000034028110099.8897bison_bison_bisonENSBBBP0000001891310099.8897
ENSG00000110321homo_sapiensENSP0000034028110099.8897monodon_monocerosENSMMNP0001502718710099.8897
ENSG00000110321homo_sapiensENSP0000034028110099.8897sus_scrofaENSSSCP0000001425095.574395.4689
ENSG00000110321homo_sapiensENSP0000034028110099.7795microcebus_murinusENSMICP0000003561097.842597.6268
ENSG00000110321homo_sapiensENSP0000034028178.2874.9724octodon_degusENSODEP0000001871789.533485.7503
ENSG00000110321homo_sapiensENSP0000034028169.349565.7111octodon_degusENSODEP0000000224288.591683.9437
ENSG00000110321homo_sapiensENSP0000034028172.657168.688octodon_degusENSODEP0000000970288.219583.4003
ENSG00000110321homo_sapiensENSP0000034028144.76344.4322jaculus_jaculusENSJJAP0000002210998.067697.343
ENSG00000110321homo_sapiensENSP0000034028110099.7795ovis_aries_rambouilletENSOARP0002001783610099.7795
ENSG00000110321homo_sapiensENSP0000034028110099.7795ursus_maritimusENSUMAP0000002201398.801798.5839
ENSG00000110321homo_sapiensENSP0000034028195.589994.8181ochotona_princepsENSOPRP0000000578895.801195.0276
ENSG00000110321homo_sapiensENSP0000034028195.700195.4796delphinapterus_leucasENSDLEP0000000863097.418697.1942
ENSG00000110321homo_sapiensENSP0000034028164.939462.2933physeter_catodonENSPCTP0000500302593.04989.2575
ENSG00000110321homo_sapiensENSP0000034028199.779598.8975mus_musculusENSMUSP0000012455199.889699.0066
ENSG00000110321homo_sapiensENSP0000034028199.779599.559dipodomys_ordiiENSDORP0000002460499.779599.559
ENSG00000110321homo_sapiensENSP0000034028110099.8897mustela_putorius_furoENSMPUP0000001278893.121193.0185
ENSG00000110321homo_sapiensENSP0000034028188.202987.4311aotus_nancymaaeENSANAP0000000641095.124994.2925
ENSG00000110321homo_sapiensENSP0000034028110099.7795saimiri_boliviensis_boliviensisENSSBOP0000002012597.109296.8951
ENSG00000110321homo_sapiensENSP0000034028199.338599.2282vicugna_pacosENSVPAP0000000946799.229199.1189
ENSG00000110321homo_sapiensENSP0000034028110099.7795chlorocebus_sabaeusENSCSAP0000000092192.55192.3469
ENSG00000110321homo_sapiensENSP0000034028187.100386.4388tupaia_belangeriENSTBEP0000000048193.601992.891
ENSG00000110321homo_sapiensENSP0000034028199.779599.118mesocricetus_auratusENSMAUP0000001168699.889699.2274
ENSG00000110321homo_sapiensENSP0000034028110099.8897phocoena_sinusENSPSNP0000000572510099.8897
ENSG00000110321homo_sapiensENSP0000034028199.669299.559camelus_dromedariusENSCDRP0000502847799.889599.779
ENSG00000110321homo_sapiensENSP0000034028176.846775.3032carlito_syrichtaENSTSYP0000002441392.07490.2246
ENSG00000110321homo_sapiensENSP0000034028110099.7795panthera_tigris_altaicaENSPTIP0000001206195.273195.063
ENSG00000110321homo_sapiensENSP0000034028199.779599.0077rattus_norvegicusENSRNOP0000008673099.889699.117
ENSG00000110321homo_sapiensENSP0000034028110099.7795prolemur_simusENSPSMP0000002992710099.7795
ENSG00000110321homo_sapiensENSP0000034028199.669298.8975microtus_ochrogasterENSMOCP0000002390799.779399.0066
ENSG00000110321homo_sapiensENSP0000034028190.187489.9669sorex_araneusENSSARP0000000970791.910191.6854
ENSG00000110321homo_sapiensENSP0000034028199.779599.0077peromyscus_maniculatus_bairdiiENSPEMP0000001544199.889699.117
ENSG00000110321homo_sapiensENSP0000034028110099.8897bos_mutusENSBMUP0000000086610099.8897
ENSG00000110321homo_sapiensENSP0000034028199.779598.8975mus_spicilegusENSMSIP0000003384599.889699.0066
ENSG00000110321homo_sapiensENSP0000034028199.669298.8975cricetulus_griseus_chok1gshdENSCGRP0000100060299.779399.0066
ENSG00000110321homo_sapiensENSP0000034028199.889799.7795pteropus_vampyrusENSPVAP0000001587410099.8896
ENSG00000110321homo_sapiensENSP0000034028199.889799.6692myotis_lucifugusENSMLUP0000001472296.794996.5812
ENSG00000110321homo_sapiensENSP0000034028199.448798.0154vombatus_ursinusENSVURP0001000548899.558598.1236
ENSG00000110321homo_sapiensENSP0000034028110099.8897rhinolophus_ferrumequinumENSRFEP0001000174810099.8897
ENSG00000110321homo_sapiensENSP0000034028110099.7795neovison_visonENSNVIP0000001303910099.7795
ENSG00000110321homo_sapiensENSP0000034028110099.8897bos_taurusENSBTAP0000004961410099.8897
ENSG00000110321homo_sapiensENSP0000034028199.779599.559heterocephalus_glaber_femaleENSHGLP0000004001099.779599.559
ENSG00000110321homo_sapiensENSP0000034028197.794997.2437rhinopithecus_bietiENSRBIP0000000867895.891995.3513
ENSG00000110321homo_sapiensENSP0000034028110099.7795canis_lupus_dingoENSCAFP0002002058198.801798.5839
ENSG00000110321homo_sapiensENSP0000034028144.873244.2117sciurus_vulgarisENSSVLP0000500635598.309296.8599
ENSG00000110321homo_sapiensENSP0000034028199.338598.0154phascolarctos_cinereusENSPCIP0000003411399.55898.232
ENSG00000110321homo_sapiensENSP0000034028195.038694.2668procavia_capensisENSPCAP0000001392695.038694.2668
ENSG00000110321homo_sapiensENSP0000034028199.779599.0077nannospalax_galiliENSNGAP0000002641599.889699.117
ENSG00000110321homo_sapiensENSP0000034028110099.8897bos_grunniensENSBGRP0000000846710099.8897
ENSG00000110321homo_sapiensENSP0000034028110099.559chinchilla_lanigeraENSCLAP0000002404487.717687.3308
ENSG00000110321homo_sapiensENSP0000034028199.11899.0077cervus_hanglu_yarkandensisENSCHYP0000000167310099.8888
ENSG00000110321homo_sapiensENSP0000034028199.889799.7795catagonus_wagneriENSCWAP0000001860599.889799.7795
ENSG00000110321homo_sapiensENSP0000034028198.787298.4565ictidomys_tridecemlineatusENSSTOP0000001219498.569998.2398
ENSG00000110321homo_sapiensENSP0000034028125.799325.6891otolemur_garnettiiENSOGAP0000001782776.221575.8958
ENSG00000110321homo_sapiensENSP0000034028110099.7795cebus_imitatorENSCCAP0000000612483.903883.7188
ENSG00000110321homo_sapiensENSP0000034028199.889799.559urocitellus_parryiiENSUPAP0001002042399.889799.559
ENSG00000110321homo_sapiensENSP0000034028199.779599.6692moschus_moschiferusENSMMSP0000001370910099.8895
ENSG00000110321homo_sapiensENSP0000034028110099.7795rhinopithecus_roxellanaENSRROP0000002830283.903883.7188
ENSG00000110321homo_sapiensENSP0000034028196.251495.8104rhinopithecus_roxellanaENSRROP0000002147899.430598.9749
ENSG00000110321homo_sapiensENSP0000034028199.779598.8975mus_pahariMGP_PahariEiJ_P001838399.889699.0066
ENSG00000110321homo_sapiensENSP0000034028110099.7795propithecus_coquereliENSPCOP0000002578292.835292.6305
ENSG00000110321homo_sapiensENSP0000034028160.308741.3451drosophila_melanogasterFBpp030682836.760825.2016
ENSG00000110321homo_sapiensENSP0000034028158.765239.14ciona_intestinalisENSCINP0000001802151.398334.2334
ENSG00000110321homo_sapiensENSP0000034028178.059564.6086petromyzon_marinusENSPMAP0000000338078.059564.6086
ENSG00000110321homo_sapiensENSP0000034028156.780644.3219eptatretus_burgeriENSEBUP0000002094371.329655.6787
ENSG00000110321homo_sapiensENSP0000034028185.997879.7133callorhinchus_miliiENSCMIP0000000591687.443981.0538
ENSG00000110321homo_sapiensENSP0000034028193.936188.3131latimeria_chalumnaeENSLACP0000002091391.318385.8521
ENSG00000110321homo_sapiensENSP0000034028193.384887.3208lepisosteus_oculatusENSLOCP0000000467390.106484.2553
ENSG00000110321homo_sapiensENSP0000034028191.069582.6902clupea_harengusENSCHAP0000005523488.059779.9574
ENSG00000110321homo_sapiensENSP0000034028191.2982.8004danio_rerioENSDARP0000007421092.204983.6303
ENSG00000110321homo_sapiensENSP0000034028190.077281.9184danio_rerioENSDARP0000001787891.694783.3895
ENSG00000110321homo_sapiensENSP0000034028189.636281.2569carassius_auratusENSCARP0000010054991.245882.716
ENSG00000110321homo_sapiensENSP0000034028189.084981.1466carassius_auratusENSCARP0000011639786.232778.5486
ENSG00000110321homo_sapiensENSP0000034028189.525981.6979carassius_auratusENSCARP0000007130887.68980.0216
ENSG00000110321homo_sapiensENSP0000034028189.415780.7056carassius_auratusENSCARP0000013333691.021382.1549
ENSG00000110321homo_sapiensENSP0000034028185.336379.0518astyanax_mexicanusENSAMXP0000001042590.104883.4691
ENSG00000110321homo_sapiensENSP0000034028186.769679.2723astyanax_mexicanusENSAMXP0000000399792.154684.192
ENSG00000110321homo_sapiensENSP0000034028183.572276.4057ictalurus_punctatusENSIPUP0000001508090.669982.8947
ENSG00000110321homo_sapiensENSP0000034028182.359473.8699ictalurus_punctatusENSIPUP0000002729587.164578.1797
ENSG00000110321homo_sapiensENSP0000034028190.407983.021esox_luciusENSELUP0000006916087.23480.1064
ENSG00000110321homo_sapiensENSP0000034028189.636281.9184esox_luciusENSELUP0000007678190.233182.4639
ENSG00000110321homo_sapiensENSP0000034028167.475261.6318electrophorus_electricusENSEEEP0000003141987.428679.8571
ENSG00000110321homo_sapiensENSP0000034028185.66777.5083electrophorus_electricusENSEEEP0000001931088.880.3429
ENSG00000110321homo_sapiensENSP0000034028189.305481.1466oncorhynchus_kisutchENSOKIP0000509847684.816877.0681
ENSG00000110321homo_sapiensENSP0000034028187.431180.5954oncorhynchus_kisutchENSOKIP0000508202389.807582.786
ENSG00000110321homo_sapiensENSP0000034028188.092681.1466oncorhynchus_kisutchENSOKIP0000504276287.898880.9681
ENSG00000110321homo_sapiensENSP0000034028187.761880.2646oncorhynchus_kisutchENSOKIP0000511632586.994579.5628
ENSG00000110321homo_sapiensENSP0000034028188.092680.7056oncorhynchus_mykissENSOMYP0000005574188.482881.0631
ENSG00000110321homo_sapiensENSP0000034028187.872181.0364oncorhynchus_mykissENSOMYP0000005080186.630479.8913
ENSG00000110321homo_sapiensENSP0000034028188.202980.2646oncorhynchus_mykissENSOMYP0000004274483.945476.3903
ENSG00000110321homo_sapiensENSP0000034028189.636281.9184oncorhynchus_mykissENSOMYP0000010824189.735182.0088
ENSG00000110321homo_sapiensENSP0000034028187.761880.1544salmo_salarENSSSAP0000009628889.639681.8694
ENSG00000110321homo_sapiensENSP0000034028185.22678.1698salmo_salarENSSSAP0000008345988.443981.1213
ENSG00000110321homo_sapiensENSP0000034028187.872180.5954salmo_salarENSSSAP0000001109487.486380.2415
ENSG00000110321homo_sapiensENSP0000034028189.856783.1312salmo_salarENSSSAP0000003706787.072680.5556
ENSG00000110321homo_sapiensENSP0000034028188.423481.1466salmo_truttaENSSTUP0000003739388.131980.8791
ENSG00000110321homo_sapiensENSP0000034028185.777379.1621salmo_truttaENSSTUP0000005260385.588678.9879
ENSG00000110321homo_sapiensENSP0000034028188.092680.2646salmo_truttaENSSTUP0000011557986.471978.7879
ENSG00000110321homo_sapiensENSP0000034028188.202980.2646salmo_truttaENSSTUP0000011031387.336279.476
ENSG00000110321homo_sapiensENSP0000034028189.084980.4851gadus_morhuaENSGMOP0000006891085.774977.4947
ENSG00000110321homo_sapiensENSP0000034028176.295564.7189gadus_morhuaENSGMOP0000003852579.540267.4713
ENSG00000110321homo_sapiensENSP0000034028186.549180.2646fundulus_heteroclitusENSFHEP0000000918792.6885.9504
ENSG00000110321homo_sapiensENSP0000034028183.572271.6648fundulus_heteroclitusENSFHEP0000000581086.43174.1163
ENSG00000110321homo_sapiensENSP0000034028192.17284.785poecilia_reticulataENSPREP0000000470289.316282.1581
ENSG00000110321homo_sapiensENSP0000034028182.138969.6803poecilia_reticulataENSPREP0000003413885.829572.8111
ENSG00000110321homo_sapiensENSP0000034028186.328679.4928xiphophorus_maculatusENSXMAP0000001356992.772585.4265
ENSG00000110321homo_sapiensENSP0000034028183.351771.0033xiphophorus_maculatusENSXMAP0000000929685.423772.7684
ENSG00000110321homo_sapiensENSP0000034028191.179783.903oryzias_latipesENSORLP0000002288988.638881.5648
ENSG00000110321homo_sapiensENSP0000034028181.036470.5623oryzias_latipesENSORLP0000000916288.023976.6467
ENSG00000110321homo_sapiensENSP0000034028183.572272.7674cyclopterus_lumpusENSCLMP0000502947386.727775.5149
ENSG00000110321homo_sapiensENSP0000034028190.187481.9184cyclopterus_lumpusENSCLMP0000502529286.836578.8747
ENSG00000110321homo_sapiensENSP0000034028178.941668.688oreochromis_niloticusENSONIP0000000757083.547372.6954
ENSG00000110321homo_sapiensENSP0000034028188.423480.9261oreochromis_niloticusENSONIP0000007833289.309681.7372
ENSG00000110321homo_sapiensENSP0000034028182.469772.1058haplochromis_burtoniENSHBUP000000160788876.9412
ENSG00000110321homo_sapiensENSP0000034028183.351776.957haplochromis_burtoniENSHBUP0000002375292.874785.7494
ENSG00000110321homo_sapiensENSP0000034028188.864481.3671astatotilapia_callipteraENSACLP0000003103589.855182.2742
ENSG00000110321homo_sapiensENSP0000034028185.66774.4212astatotilapia_callipteraENSACLP0000000065083.369172.4249
ENSG00000110321homo_sapiensENSP0000034028184.674874.3109sparus_aurataENSSAUP0001005112483.206973.0228
ENSG00000110321homo_sapiensENSP0000034028188.092681.1466sparus_aurataENSSAUP0001001585591.733684.5006
ENSG00000110321homo_sapiensENSP0000034028192.502885.1158lates_calcariferENSLCAP0001005632691.69484.3716
ENSG00000110321homo_sapiensENSP0000034028178.059568.3572lates_calcariferENSLCAP0001005899484.68974.1627
ENSG00000110321homo_sapiensENSP0000034028185.115874.5314lates_calcariferENSLCAP0001003404787.133276.298
ENSG00000110321homo_sapiensENSP0000034028193.384886.3286xenopus_tropicalisENSXETP0000002993194.320787.1938
ENSG00000110321homo_sapiensENSP0000034028192.723388.8644chrysemys_picta_belliiENSCPBP0000000659486.9783.3506
ENSG00000110321homo_sapiensENSP0000034028197.023294.4873sphenodon_punctatusENSSPUP0000001802997.56195.0111
ENSG00000110321homo_sapiensENSP0000034028193.825890.6284crocodylus_porosusENSCPRP0000500844693.413890.2305
ENSG00000110321homo_sapiensENSP0000034028196.692492.613laticauda_laticaudataENSLLTP0000002204597.336393.2297
ENSG00000110321homo_sapiensENSP0000034028196.692492.7233notechis_scutatusENSNSUP0000001923393.997990.1393
ENSG00000110321homo_sapiensENSP0000034028196.692492.613pseudonaja_textilisENSPTXP0000000367093.001189.0774
ENSG00000110321homo_sapiensENSP0000034028191.620789.6362anas_platyrhynchos_platyrhynchosENSAPLP0000000535596.180694.0972
ENSG00000110321homo_sapiensENSP0000034028192.723390.2977gallus_gallusENSGALP0001003010597.33894.7917
ENSG00000110321homo_sapiensENSP0000034028194.046391.4002meleagris_gallopavoENSMGAP0000000584694.254191.6022
ENSG00000110321homo_sapiensENSP0000034028195.479692.8335serinus_canariaENSSCAP0000001077396.008993.3481
ENSG00000110321homo_sapiensENSP0000034028194.377191.4002parus_majorENSPMJP0000000670591.747188.8532
ENSG00000110321homo_sapiensENSP0000034028193.274589.8567anolis_carolinensisENSACAP0000003947092.763289.364
ENSG00000110321homo_sapiensENSP0000034028185.556878.6108neolamprologus_brichardiENSNBRP0000001886990.337683.0035
ENSG00000110321homo_sapiensENSP0000034028180.485170.1213neolamprologus_brichardiENSNBRP0000001521488.164376.8116
ENSG00000110321homo_sapiensENSP0000034028196.582192.7233naja_najaENSNNAP0000002010993.689889.9465
ENSG00000110321homo_sapiensENSP0000034028191.179787.4311podarcis_muralisENSPMRP0000000274188.260484.6318
ENSG00000110321homo_sapiensENSP0000034028196.141193.2745geospiza_fortisENSGFOP0000002247596.674193.7916
ENSG00000110321homo_sapiensENSP0000034028196.912994.1566taeniopygia_guttataENSTGUP0000003119494.719892.0259
ENSG00000110321homo_sapiensENSP0000034028192.723385.0055erpetoichthys_calabaricusENSECRP0000000752389.946582.4599
ENSG00000110321homo_sapiensENSP0000034028187.431180.8159kryptolebias_marmoratusENSKMAP0000000837092.316785.3318
ENSG00000110321homo_sapiensENSP0000034028180.705670.5623kryptolebias_marmoratusENSKMAP0000000756384.722274.0741
ENSG00000110321homo_sapiensENSP0000034028194.707891.6207salvator_merianaeENSSMRP0000002050394.707891.6207
ENSG00000110321homo_sapiensENSP0000034028182.028771.4443oryzias_javanicusENSOJAP0000003723685.813174.7405
ENSG00000110321homo_sapiensENSP0000034028190.518282.8004oryzias_javanicusENSOJAP0000001455486.512179.1359
ENSG00000110321homo_sapiensENSP0000034028182.028771.1136amphilophus_citrinellusENSACIP0000000025885.714374.3088
ENSG00000110321homo_sapiensENSP0000034028187.210680.7056amphilophus_citrinellusENSACIP0000000992691.445184.6243
ENSG00000110321homo_sapiensENSP0000034028183.572273.2084dicentrarchus_labraxENSDLAP0000508355786.332675.6264
ENSG00000110321homo_sapiensENSP0000034028192.282284.785dicentrarchus_labraxENSDLAP0000504589189.042681.8085
ENSG00000110321homo_sapiensENSP0000034028140.463135.0606amphiprion_perculaENSAPEP0000001462389.077777.1845
ENSG00000110321homo_sapiensENSP0000034028191.069583.6825amphiprion_perculaENSAPEP0000002002091.574384.1463
ENSG00000110321homo_sapiensENSP0000034028174.531468.688oryzias_sinensisENSOSIP0000003529487.001380.1802
ENSG00000110321homo_sapiensENSP0000034028195.589992.7233pelodiscus_sinensisENSPSIP0000001989293.326290.5275
ENSG00000110321homo_sapiensENSP0000034028195.920692.7233gopherus_evgoodeiENSGEVP0000500494792.849589.7545
ENSG00000110321homo_sapiensENSP0000034028182.910780.2646chelonoidis_abingdoniiENSCABP0000002803191.041288.1356
ENSG00000110321homo_sapiensENSP0000034028183.241573.4289seriola_dumeriliENSSDUP0000003247487.892977.532
ENSG00000110321homo_sapiensENSP0000034028187.651681.2569seriola_dumeriliENSSDUP0000000641092.013985.3009
ENSG00000110321homo_sapiensENSP0000034028189.305481.3671cottoperca_gobioENSCGOP0000002296490.909182.8283
ENSG00000110321homo_sapiensENSP0000034028185.887574.6417cottoperca_gobioENSCGOP0000004637582.696471.8684
ENSG00000110321homo_sapiensENSP0000034028197.243794.7078struthio_camelus_australisENSSCUP0000001535092.452890.0419
ENSG00000110321homo_sapiensENSP0000034028197.023294.8181anser_brachyrhynchusENSABRP0000002693794.319492.1758
ENSG00000110321homo_sapiensENSP0000034028189.856781.4774gasterosteus_aculeatusENSGACP0000001257987.165879.0374
ENSG00000110321homo_sapiensENSP0000034028166.152257.3319gasterosteus_aculeatusENSGACP0000002072286.330974.8201
ENSG00000110321homo_sapiensENSP0000034028192.17284.8953cynoglossus_semilaevisENSCSEP0000003324388.278881.3094
ENSG00000110321homo_sapiensENSP0000034028181.697970.452cynoglossus_semilaevisENSCSEP0000003044683.071771.6368
ENSG00000110321homo_sapiensENSP0000034028192.17284.8953poecilia_formosaENSPFOP0000001575189.507582.4411
ENSG00000110321homo_sapiensENSP0000034028182.469770.3418poecilia_formosaENSPFOP0000001191287.485474.6199
ENSG00000110321homo_sapiensENSP0000034028182.690276.075myripristis_murdjanENSMMDP0000503680190.79983.5351
ENSG00000110321homo_sapiensENSP0000034028190.84981.8082myripristis_murdjanENSMMDP0000504047987.846579.1045
ENSG00000110321homo_sapiensENSP0000034028189.195280.9261sander_luciopercaENSSLUP0000004404986.524178.5027
ENSG00000110321homo_sapiensENSP0000034028184.564573.9802sander_luciopercaENSSLUP0000000635086.373975.5631
ENSG00000110321homo_sapiensENSP0000034028195.369392.8335strigops_habroptilaENSSHBP0000501949196.756194.1834
ENSG00000110321homo_sapiensENSP0000034028179.382669.4598amphiprion_ocellarisENSAOCP0000000985886.330975.5396
ENSG00000110321homo_sapiensENSP0000034028187.761880.9261amphiprion_ocellarisENSAOCP0000000960092.129684.9537
ENSG00000110321homo_sapiensENSP0000034028185.005582.3594terrapene_carolina_triunguisENSTMTP0000000646894.833991.8819
ENSG00000110321homo_sapiensENSP0000034028187.320879.6031hucho_huchoENSHHUP0000005790290.721682.7033
ENSG00000110321homo_sapiensENSP0000034028188.202981.4774hucho_huchoENSHHUP0000008221188.593681.8383
ENSG00000110321homo_sapiensENSP0000034028187.761880.1544hucho_huchoENSHHUP0000006634488.248380.5987
ENSG00000110321homo_sapiensENSP0000034028188.092680.2646hucho_huchoENSHHUP0000004504883.490176.0711
ENSG00000110321homo_sapiensENSP0000034028192.17285.3363betta_splendensENSBSLP0000003288786.902380.4574
ENSG00000110321homo_sapiensENSP0000034028183.682571.9956betta_splendensENSBSLP0000001350285.569373.6189
ENSG00000110321homo_sapiensENSP0000034028184.895378.5005pygocentrus_nattereriENSPNAP0000000904191.885484.9642
ENSG00000110321homo_sapiensENSP0000034028184.34476.957pygocentrus_nattereriENSPNAP0000003076892.168784.0964
ENSG00000110321homo_sapiensENSP0000034028190.077282.8004anabas_testudineusENSATEP0000004703692.946585.438
ENSG00000110321homo_sapiensENSP0000034028184.78574.2007anabas_testudineusENSATEP0000000865687.287276.3905
ENSG00000110321homo_sapiensENSP0000034028158.765238.3682ciona_savignyiENSCSAVP0000001272054.166735.3659
ENSG00000110321homo_sapiensENSP0000034028129.217214.8842saccharomyces_cerevisiaeYGL049C28.993414.7702
ENSG00000110321homo_sapiensENSP0000034028131.201817.3098saccharomyces_cerevisiaeYGR162W29.726916.4916
ENSG00000110321homo_sapiensENSP0000034028186.549176.1852seriola_lalandi_dorsalisENSSLDP0000002831381.770871.9792
ENSG00000110321homo_sapiensENSP0000034028187.651681.2569seriola_lalandi_dorsalisENSSLDP0000003018892.013985.3009
ENSG00000110321homo_sapiensENSP0000034028185.005573.0981labrus_bergyltaENSLBEP0000003604584.354572.5383
ENSG00000110321homo_sapiensENSP0000034028188.313181.1466labrus_bergyltaENSLBEP0000000298190.508583.1638
ENSG00000110321homo_sapiensENSP0000034028185.556878.6108pundamilia_nyerereiENSPNYP0000001639090.337683.0035
ENSG00000110321homo_sapiensENSP0000034028185.556874.2007pundamilia_nyerereiENSPNYP0000001199083.261872.2103
ENSG00000110321homo_sapiensENSP0000034028191.179784.344mastacembelus_armatusENSMAMP0000006147388.354781.7308
ENSG00000110321homo_sapiensENSP0000034028184.895374.0904mastacembelus_armatusENSMAMP0000005018987.202776.1042
ENSG00000110321homo_sapiensENSP0000034028182.028771.1136stegastes_partitusENSSPAP0000001661483.408172.3094
ENSG00000110321homo_sapiensENSP0000034028185.556878.8313stegastes_partitusENSSPAP0000001606791.943184.7156
ENSG00000110321homo_sapiensENSP0000034028188.754181.3671oncorhynchus_tshawytschaENSOTSP0000504453086.839379.6116
ENSG00000110321homo_sapiensENSP0000034028184.564577.398oncorhynchus_tshawytschaENSOTSP0000507954587.657180.2286
ENSG00000110321homo_sapiensENSP0000034028188.864480.7056oncorhynchus_tshawytschaENSOTSP0000505412288.183880.0875
ENSG00000110321homo_sapiensENSP0000034028189.746481.8082oncorhynchus_tshawytschaENSOTSP0000503463885.774578.1876
ENSG00000110321homo_sapiensENSP0000034028187.761880.9261acanthochromis_polyacanthusENSAPOP0000001370792.129684.9537
ENSG00000110321homo_sapiensENSP0000034028183.131272.2161acanthochromis_polyacanthusENSAPOP0000002919586.866475.4608
ENSG00000110321homo_sapiensENSP0000034028194.928392.2822aquila_chrysaetos_chrysaetosENSACCP0002002368595.348892.691
ENSG00000110321homo_sapiensENSP0000034028188.864481.4774nothobranchius_furzeriENSNFUP0001505284090.460282.9405
ENSG00000110321homo_sapiensENSP0000034028183.572271.9956nothobranchius_furzeriENSNFUP0001501815579.288768.3054
ENSG00000110321homo_sapiensENSP0000034028183.46272.1058cyprinodon_variegatusENSCVAP0000001511585.151973.5658
ENSG00000110321homo_sapiensENSP0000034028187.320880.5954cyprinodon_variegatusENSCVAP0000000671991.560784.5087
ENSG00000110321homo_sapiensENSP0000034028191.179783.021denticeps_clupeoidesENSDCDP0000004373287.885280.0213
ENSG00000110321homo_sapiensENSP0000034028192.17284.785larimichthys_croceaENSLCRP0000503640588.278881.2038
ENSG00000110321homo_sapiensENSP0000034028184.34474.0904larimichthys_croceaENSLCRP0000500048287.93177.2414
ENSG00000110321homo_sapiensENSP0000034028179.162168.4675takifugu_rubripesENSTRUP0000004474667.799858.6402
ENSG00000110321homo_sapiensENSP0000034028196.802694.1566ficedula_albicollisENSFALP0000002230493.30590.7545
ENSG00000110321homo_sapiensENSP0000034028186.328678.5005hippocampus_comesENSHCOP0000001325290.7382.5029
ENSG00000110321homo_sapiensENSP0000034028182.800471.2238hippocampus_comesENSHCOP0000001818184.287372.5028
ENSG00000110321homo_sapiensENSP0000034028190.959282.3594cyprinus_carpio_carpioENSCCRP0000001208888.519380.1502
ENSG00000110321homo_sapiensENSP0000034028189.746481.2569cyprinus_carpio_carpioENSCCRP0000001183291.35882.716
ENSG00000110321homo_sapiensENSP0000034028187.651679.9338cyprinus_carpio_carpioENSCCRP0000010807285.575978.0409
ENSG00000110321homo_sapiensENSP0000034028190.297782.1389cyprinus_carpio_carpioENSCCRP0000005631789.021780.9783
ENSG00000110321homo_sapiensENSP0000034028196.692494.1566coturnix_japonicaENSCJPP0000500246293.297990.8511
ENSG00000110321homo_sapiensENSP0000034028184.123571.4443poecilia_latipinnaENSPLAP0000001522186.312273.3032
ENSG00000110321homo_sapiensENSP0000034028186.769679.9338poecilia_latipinnaENSPLAP0000001540393.136185.7988
ENSG00000110321homo_sapiensENSP0000034028190.297781.1466sinocyclocheilus_grahamiENSSGRP0000002792791.919282.6038
ENSG00000110321homo_sapiensENSP0000034028153.803747.9603sinocyclocheilus_grahamiENSSGRP0000001608187.142977.6786
ENSG00000110321homo_sapiensENSP0000034028186.659378.8313sinocyclocheilus_grahamiENSSGRP0000005652686.75578.9183
ENSG00000110321homo_sapiensENSP0000034028190.297781.5877sinocyclocheilus_grahamiENSSGRP0000006759287.687479.2291
ENSG00000110321homo_sapiensENSP0000034028183.241571.8853maylandia_zebraENSMZEP0000501963883.425472.0442
ENSG00000110321homo_sapiensENSP0000034028185.556878.6108maylandia_zebraENSMZEP0000501743390.337683.0035
ENSG00000110321homo_sapiensENSP0000034028191.179783.021tetraodon_nigroviridisENSTNIP0000001672191.685183.4812
ENSG00000110321homo_sapiensENSP0000034028182.138970.011tetraodon_nigroviridisENSTNIP0000001223180.802668.872
ENSG00000110321homo_sapiensENSP0000034028184.454277.839paramormyrops_kingsleyaeENSPKIP0000003021791.190584.0476
ENSG00000110321homo_sapiensENSP0000034028190.297782.9107paramormyrops_kingsleyaeENSPKIP0000000647590.09982.7283
ENSG00000110321homo_sapiensENSP0000034028190.407982.4697scleropages_formosusENSSFOP0001505488290.70882.7434
ENSG00000110321homo_sapiensENSP0000034028190.187483.5722scleropages_formosusENSSFOP0001502156491.294684.5982
ENSG00000110321homo_sapiensENSP0000034028194.156687.8721leptobrachium_leishanenseENSLLEP0000003701494.573688.2614
ENSG00000110321homo_sapiensENSP0000034028184.233772.9879scophthalmus_maximusENSSMAP0000003506679.17168.601
ENSG00000110321homo_sapiensENSP0000034028190.518282.1389scophthalmus_maximusENSSMAP0000005931988.090179.9356
ENSG00000110321homo_sapiensENSP0000034028156.119148.4013oryzias_melastigmaENSOMEP0000000065784.97573.2888
ENSG00000110321homo_sapiensENSP0000034028185.777377.1775oryzias_melastigmaENSOMEP0000002101186.540677.8643

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003729enables mRNA binding1IBAHomo_sapiens(9606)Function
GO:0003743enables translation initiation factor activity2IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0005912located_in adherens junction1HDAHomo_sapiens(9606)Component
GO:0006413involved_in translational initiation1IEAHomo_sapiens(9606)Process
GO:0006446involved_in regulation of translational initiation1IDAHomo_sapiens(9606)Process
GO:0007507involved_in heart development1IEAHomo_sapiens(9606)Process
GO:0008135enables translation factor activity, RNA binding1IDAHomo_sapiens(9606)Function
GO:0008219involved_in cell death1TASHomo_sapiens(9606)Process
GO:0009059involved_in macromolecule biosynthetic process1IGIHomo_sapiens(9606)Process
GO:0010507involved_in negative regulation of autophagy1IMPHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016281part_of eukaryotic translation initiation factor 4F complex2IBA,IDAHomo_sapiens(9606)Component
GO:0030307involved_in positive regulation of cell growth1IMPHomo_sapiens(9606)Process
GO:0030424located_in axon1IEAHomo_sapiens(9606)Component
GO:0045296enables cadherin binding1HDAHomo_sapiens(9606)Function
GO:0045727involved_in positive regulation of translation1IEAHomo_sapiens(9606)Process
GO:0045773involved_in positive regulation of axon extension1IEAHomo_sapiens(9606)Process
GO:0051726involved_in regulation of cell cycle1TASHomo_sapiens(9606)Process
GO:0060999involved_in positive regulation of dendritic spine development1IEAHomo_sapiens(9606)Process

Expression