Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerSARS-COV-OC43FlavivirusesSARS-COV-2DengueZika
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Transmemebrane
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000108829 Gene ID 55379 Accession 28817
Symbol LRRC59 Alias Full Name
Status Confidence Length 22465 bases Strand Minus strand
Position 17 : 50375059 - 50397523 RNA binding domain N.A.
Summary

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
32788342 Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane. M Molly Hannigan 2020-11-01 Molecular & cellular proteomics : MCP

Transcripts

Name Transcript ID bp Protein Translation ID
LRRC59-202 ENST00000503118 438 57aa ENSP00000459616
LRRC59-201 ENST00000225972 2880 307aa ENSP00000225972
LRRC59-203 ENST00000576448 1531 62aa ENSP00000459305

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
43743Platelet Function Tests3.5715381E-006-
45192Platelet Function Tests8.8944960E-006-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000108829

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000108829homo_sapiensENSP0000022597299.674399.0228nomascus_leucogenysENSNLEP0000003264399.674399.0228
ENSG00000108829homo_sapiensENSP00000225972100100pan_paniscusENSPPAP00000030315100100
ENSG00000108829homo_sapiensENSP0000022597283.387677.1987pongo_abeliiENSPPYP0000002507171.111165.8333
ENSG00000108829homo_sapiensENSP00000225972100100pan_troglodytesENSPTRP00000015962100100
ENSG00000108829homo_sapiensENSP00000225972100100gorilla_gorillaENSGGOP00000027098100100
ENSG00000108829homo_sapiensENSP0000022597275.244366.7752ornithorhynchus_anatinusENSOANP000000542116053.2468
ENSG00000108829homo_sapiensENSP0000022597289.250881.4332sarcophilus_harrisiiENSSHAP0000002730588.96181.1688
ENSG00000108829homo_sapiensENSP0000022597244.951139.0879notamacropus_eugeniiENSMEUP0000000430384.146373.1707
ENSG00000108829homo_sapiensENSP0000022597260.586359.2834choloepus_hoffmanniENSCHOP0000000453660.784359.4771
ENSG00000108829homo_sapiensENSP0000022597297.394193.8111dasypus_novemcinctusENSDNOP0000002344782.369179.3388
ENSG00000108829homo_sapiensENSP0000022597297.068493.8111erinaceus_europaeusENSEEUP0000000972397.385694.1176
ENSG00000108829homo_sapiensENSP0000022597289.250884.0391echinops_telfairiENSETEP0000000780889.836184.5902
ENSG00000108829homo_sapiensENSP0000022597286.970785.0163callithrix_jacchusENSCJAP0000008204279.228577.4481
ENSG00000108829homo_sapiensENSP0000022597299.674399.0228callithrix_jacchusENSCJAP0000006657599.674399.0228
ENSG00000108829homo_sapiensENSP0000022597210099.3485cercocebus_atysENSCATP0000000460310099.3485
ENSG00000108829homo_sapiensENSP0000022597210099.6743macaca_mulattaENSMMUP0000004929410099.6743
ENSG00000108829homo_sapiensENSP0000022597210099.6743macaca_nemestrinaENSMNEP0000000527610099.6743
ENSG00000108829homo_sapiensENSP0000022597210099.6743papio_anubisENSPANP0000002025510099.6743
ENSG00000108829homo_sapiensENSP0000022597210099.6743mandrillus_leucophaeusENSMLEP0000003516810099.6743
ENSG00000108829homo_sapiensENSP0000022597297.394193.4853tursiops_truncatusENSTTRP0000000019397.394193.4853
ENSG00000108829homo_sapiensENSP0000022597297.068493.8111vulpes_vulpesENSVVUP0000000612297.385694.1176
ENSG00000108829homo_sapiensENSP0000022597297.719995.4397mus_spretusMGP_SPRETEiJ_P003071497.719995.4397
ENSG00000108829homo_sapiensENSP0000022597297.394195.114equus_asinusENSEASP0000502731297.712495.4248
ENSG00000108829homo_sapiensENSP0000022597253.745950.8143equus_asinusENSEASP0000500840991.160286.1878
ENSG00000108829homo_sapiensENSP0000022597298.045695.4397capra_hircusENSCHIP0000000397398.36695.7516
ENSG00000108829homo_sapiensENSP0000022597298.045695.4397loxodonta_africanaENSLAFP0000000039198.045695.4397
ENSG00000108829homo_sapiensENSP0000022597298.045695.7655panthera_leoENSPLOP0000002582098.36696.0784
ENSG00000108829homo_sapiensENSP0000022597297.068493.8111ailuropoda_melanoleucaENSAMEP0000001246965.494563.2967
ENSG00000108829homo_sapiensENSP0000022597297.719995.114bos_indicus_hybridENSBIXP0000502915598.039295.4248
ENSG00000108829homo_sapiensENSP0000022597298.697197.0684oryctolagus_cuniculusENSOCUP0000000397898.697197.0684
ENSG00000108829homo_sapiensENSP0000022597297.394195.4397equus_caballusENSECAP0000001572597.712495.7516
ENSG00000108829homo_sapiensENSP0000022597254.397451.4658equus_caballusENSECAP0000003734492.265287.2928
ENSG00000108829homo_sapiensENSP0000022597297.394193.8111canis_lupus_familiarisENSCAFP0084501783297.712494.1176
ENSG00000108829homo_sapiensENSP0000022597298.045695.7655panthera_pardusENSPPRP0000001966698.36696.0784
ENSG00000108829homo_sapiensENSP0000022597298.697197.3941marmota_marmota_marmotaENSMMMP0000002560498.697197.3941
ENSG00000108829homo_sapiensENSP0000022597296.742792.1824balaenoptera_musculusENSBMSP0001003121383.898379.9435
ENSG00000108829homo_sapiensENSP0000022597295.439791.8567cavia_porcellusENSCPOP0000002813195.439791.8567
ENSG00000108829homo_sapiensENSP0000022597298.045695.7655felis_catusENSFCAP0000002555298.36696.0784
ENSG00000108829homo_sapiensENSP0000022597297.068492.8339ursus_americanusENSUAMP0000001408197.385693.1373
ENSG00000108829homo_sapiensENSP0000022597288.925181.1075monodelphis_domesticaENSMODP0000002613388.925181.1075
ENSG00000108829homo_sapiensENSP0000022597297.719995.114bison_bison_bisonENSBBBP0000001276198.039295.4248
ENSG00000108829homo_sapiensENSP0000022597298.045694.1368monodon_monocerosENSMMNP0001503025498.045694.1368
ENSG00000108829homo_sapiensENSP0000022597246.905543.3225monodon_monocerosENSMMNP0001502179070.243964.8781
ENSG00000108829homo_sapiensENSP0000022597295.765592.5081sus_scrofaENSSSCP0000007677094.838791.6129
ENSG00000108829homo_sapiensENSP0000022597298.045697.3941microcebus_murinusENSMICP0000001710598.045697.3941
ENSG00000108829homo_sapiensENSP0000022597297.068495.114octodon_degusENSODEP0000002310297.068495.114
ENSG00000108829homo_sapiensENSP0000022597297.719995.4397jaculus_jaculusENSJJAP0000000445197.719995.4397
ENSG00000108829homo_sapiensENSP0000022597297.719995.4397ovis_aries_rambouilletENSOARP0002001668098.039295.7516
ENSG00000108829homo_sapiensENSP0000022597285.34281.4332ursus_maritimusENSUMAP0000002023987.043283.0565
ENSG00000108829homo_sapiensENSP0000022597297.068495.4397ochotona_princepsENSOPRP0000001209697.068495.4397
ENSG00000108829homo_sapiensENSP0000022597298.045694.1368delphinapterus_leucasENSDLEP0000000709398.045694.1368
ENSG00000108829homo_sapiensENSP0000022597247.231343.6482delphinapterus_leucasENSDLEP0000002977170.731765.3659
ENSG00000108829homo_sapiensENSP0000022597297.068492.8339physeter_catodonENSPCTP0000503173997.068492.8339
ENSG00000108829homo_sapiensENSP0000022597247.231344.6254physeter_catodonENSPCTP0000500074568.720464.9289
ENSG00000108829homo_sapiensENSP0000022597298.045695.4397mus_caroliMGP_CAROLIEiJ_P002929798.045695.4397
ENSG00000108829homo_sapiensENSP0000022597297.719995.4397mus_musculusENSMUSP0000002123997.719995.4397
ENSG00000108829homo_sapiensENSP0000022597297.394194.7883dipodomys_ordiiENSDORP0000002404697.394194.7883
ENSG00000108829homo_sapiensENSP0000022597297.394193.1596mustela_putorius_furoENSMPUP0000001534597.712493.4641
ENSG00000108829homo_sapiensENSP0000022597299.674399.0228aotus_nancymaaeENSANAP0000000703999.674399.0228
ENSG00000108829homo_sapiensENSP0000022597299.674398.6971saimiri_boliviensis_boliviensisENSSBOP0000000294999.674398.6971
ENSG00000108829homo_sapiensENSP0000022597262.540760.2606vicugna_pacosENSVPAP0000000399896.482492.9648
ENSG00000108829homo_sapiensENSP0000022597210099.6743chlorocebus_sabaeusENSCSAP0000000172210099.6743
ENSG00000108829homo_sapiensENSP0000022597273.941473.2899tupaia_belangeriENSTBEP0000001396273.941473.2899
ENSG00000108829homo_sapiensENSP0000022597297.068493.8111mesocricetus_auratusENSMAUP0000002315397.068493.8111
ENSG00000108829homo_sapiensENSP0000022597291.856786.9707phocoena_sinusENSPSNP0000001786578.551574.3733
ENSG00000108829homo_sapiensENSP0000022597296.742793.8111camelus_dromedariusENSCDRP0000503239997.058894.1176
ENSG00000108829homo_sapiensENSP0000022597297.719996.7427carlito_syrichtaENSTSYP0000003480298.039297.0588
ENSG00000108829homo_sapiensENSP0000022597272.964270.3583carlito_syrichtaENSTSYP0000000915887.843184.7059
ENSG00000108829homo_sapiensENSP0000022597298.045695.7655panthera_tigris_altaicaENSPTIP0000000288898.36696.0784
ENSG00000108829homo_sapiensENSP0000022597296.416994.4625rattus_norvegicusENSRNOP0000000494196.416994.4625
ENSG00000108829homo_sapiensENSP0000022597298.045697.0684prolemur_simusENSPSMP0000003476198.045697.0684
ENSG00000108829homo_sapiensENSP0000022597297.068493.8111microtus_ochrogasterENSMOCP0000001512997.068493.8111
ENSG00000108829homo_sapiensENSP0000022597293.485390.5537sorex_araneusENSSARP0000000182493.485390.5537
ENSG00000108829homo_sapiensENSP0000022597297.068493.8111peromyscus_maniculatus_bairdiiENSPEMP0000002962397.068493.8111
ENSG00000108829homo_sapiensENSP0000022597297.394194.7883bos_mutusENSBMUP0000002957897.712495.098
ENSG00000108829homo_sapiensENSP0000022597297.394195.114mus_spicilegusENSMSIP0000000277897.394195.114
ENSG00000108829homo_sapiensENSP0000022597297.068494.7883cricetulus_griseus_chok1gshdENSCGRP0000100298497.068494.7883
ENSG00000108829homo_sapiensENSP0000022597297.394195.114pteropus_vampyrusENSPVAP0000001565197.712495.4248
ENSG00000108829homo_sapiensENSP0000022597294.788392.8339myotis_lucifugusENSMLUP0000000506595.09893.1373
ENSG00000108829homo_sapiensENSP0000022597289.576581.759vombatus_ursinusENSVURP0001002801489.576581.759
ENSG00000108829homo_sapiensENSP0000022597297.394194.7883rhinolophus_ferrumequinumENSRFEP0001003210897.712495.098
ENSG00000108829homo_sapiensENSP0000022597297.068492.5081neovison_visonENSNVIP0000000942697.385692.8105
ENSG00000108829homo_sapiensENSP0000022597297.719995.114bos_taurusENSBTAP0000000797898.039295.4248
ENSG00000108829homo_sapiensENSP0000022597297.394193.8111heterocephalus_glaber_femaleENSHGLP0000003140786.918683.7209
ENSG00000108829homo_sapiensENSP0000022597210099.3485rhinopithecus_bietiENSRBIP0000001928710099.3485
ENSG00000108829homo_sapiensENSP0000022597297.394193.8111canis_lupus_dingoENSCAFP0002003018397.712494.1176
ENSG00000108829homo_sapiensENSP0000022597258.306257.0033sciurus_vulgarisENSSVLP0000502275096.756894.5946
ENSG00000108829homo_sapiensENSP0000022597298.371396.7427sciurus_vulgarisENSSVLP0000500116298.371396.7427
ENSG00000108829homo_sapiensENSP0000022597289.576581.759phascolarctos_cinereusENSPCIP0000004134289.576581.759
ENSG00000108829homo_sapiensENSP0000022597276.547274.5928procavia_capensisENSPCAP0000000239786.397184.1912
ENSG00000108829homo_sapiensENSP0000022597298.371395.7655nannospalax_galiliENSNGAP0000001434198.371395.7655
ENSG00000108829homo_sapiensENSP0000022597290.553787.9479bos_grunniensENSBGRP0000000990298.233295.4064
ENSG00000108829homo_sapiensENSP0000022597296.742794.4625chinchilla_lanigeraENSCLAP0000001840596.742794.4625
ENSG00000108829homo_sapiensENSP0000022597297.719995.4397cervus_hanglu_yarkandensisENSCHYP0000000484398.039295.7516
ENSG00000108829homo_sapiensENSP0000022597297.394194.7883catagonus_wagneriENSCWAP0000002936597.712495.098
ENSG00000108829homo_sapiensENSP0000022597298.371397.0684ictidomys_tridecemlineatusENSSTOP0000000798198.371397.0684
ENSG00000108829homo_sapiensENSP0000022597298.371397.3941otolemur_garnettiiENSOGAP0000001859987.790786.9186
ENSG00000108829homo_sapiensENSP0000022597299.674399.0228cebus_imitatorENSCCAP0000002562299.674399.0228
ENSG00000108829homo_sapiensENSP0000022597298.697197.0684urocitellus_parryiiENSUPAP0001000692098.697197.0684
ENSG00000108829homo_sapiensENSP0000022597297.394194.4625moschus_moschiferusENSMMSP0000003316797.712494.7712
ENSG00000108829homo_sapiensENSP0000022597210099.3485rhinopithecus_roxellanaENSRROP0000001354910099.3485
ENSG00000108829homo_sapiensENSP0000022597297.719995.4397mus_pahariMGP_PahariEiJ_P003600997.719995.4397
ENSG00000108829homo_sapiensENSP0000022597298.045697.3941propithecus_coquereliENSPCOP0000001615998.045697.3941
ENSG00000108829homo_sapiensENSP0000022597242.996728.3388ciona_intestinalisENSCINP0000002690453.01234.9398
ENSG00000108829homo_sapiensENSP0000022597266.449548.8599petromyzon_marinusENSPMAP0000000679163.7546.875
ENSG00000108829homo_sapiensENSP0000022597264.169446.5798eptatretus_burgeriENSEBUP0000002276762.738945.5414
ENSG00000108829homo_sapiensENSP0000022597276.547259.2834callorhinchus_miliiENSCMIP0000000029977.557860.066
ENSG00000108829homo_sapiensENSP0000022597279.804667.7524latimeria_chalumnaeENSLACP0000001711078.778166.881
ENSG00000108829homo_sapiensENSP0000022597274.592855.3746xenopus_tropicalisENSXETP0000006765374.350655.1948
ENSG00000108829homo_sapiensENSP0000022597284.364872.6384chrysemys_picta_belliiENSCPBP0000004104984.640572.8758
ENSG00000108829homo_sapiensENSP0000022597282.084772.3127sphenodon_punctatusENSSPUP0000001320382.084772.3127
ENSG00000108829homo_sapiensENSP0000022597278.827464.8208laticauda_laticaudataENSLLTP0000002171573.556260.4863
ENSG00000108829homo_sapiensENSP0000022597280.781866.4495notechis_scutatusENSNSUP0000001816281.311566.8852
ENSG00000108829homo_sapiensENSP0000022597280.781866.4495pseudonaja_textilisENSPTXP0000000479481.311566.8852
ENSG00000108829homo_sapiensENSP0000022597284.039171.0098anas_platyrhynchos_platyrhynchosENSAPLP0000001759275.882464.1176
ENSG00000108829homo_sapiensENSP0000022597284.364871.6612gallus_gallusENSGALP0001004438076.401264.8968
ENSG00000108829homo_sapiensENSP0000022597277.198764.8208meleagris_gallopavoENSMGAP0000001749575.477763.3758
ENSG00000108829homo_sapiensENSP0000022597281.433269.3811serinus_canariaENSSCAP0000000044277.881666.3551
ENSG00000108829homo_sapiensENSP0000022597284.364873.2899parus_majorENSPMJP0000002493384.640573.5294
ENSG00000108829homo_sapiensENSP0000022597282.410471.3355anolis_carolinensisENSACAP0000002535474.411864.4118
ENSG00000108829homo_sapiensENSP0000022597271.98758.3062naja_najaENSNNAP0000001104961.904850.1401
ENSG00000108829homo_sapiensENSP0000022597282.736269.7068podarcis_muralisENSPMRP0000002114483.006569.9346
ENSG00000108829homo_sapiensENSP0000022597272.312761.5635geospiza_fortisENSGFOP0000000587278.723467.0213
ENSG00000108829homo_sapiensENSP0000022597283.713472.6384taeniopygia_guttataENSTGUP0000000920583.986972.8758
ENSG00000108829homo_sapiensENSP0000022597281.75969.3811salvator_merianaeENSSMRP0000003030082.295169.8361
ENSG00000108829homo_sapiensENSP0000022597284.364872.6384pelodiscus_sinensisENSPSIP0000000755084.640572.8758
ENSG00000108829homo_sapiensENSP0000022597284.364872.3127gopherus_evgoodeiENSGEVP0000501446684.640572.549
ENSG00000108829homo_sapiensENSP0000022597274.918664.1694chelonoidis_abingdoniiENSCABP0000001596861.170252.3936
ENSG00000108829homo_sapiensENSP0000022597269.381159.2834struthio_camelus_australisENSSCUP0000001555583.529471.3726
ENSG00000108829homo_sapiensENSP0000022597284.364871.987anser_brachyrhynchusENSABRP0000001805261.666752.619
ENSG00000108829homo_sapiensENSP0000022597285.016373.9414strigops_habroptilaENSSHBP0000501759061.995353.9192
ENSG00000108829homo_sapiensENSP0000022597284.364872.3127terrapene_carolina_triunguisENSTMTP0000002250676.854665.8754
ENSG00000108829homo_sapiensENSP0000022597252.44335.1792ciona_savignyiENSCSAVP0000001533666.80544.8133
ENSG00000108829homo_sapiensENSP0000022597285.993574.5928aquila_chrysaetos_chrysaetosENSACCP0002000388252.694645.7086
ENSG00000108829homo_sapiensENSP0000022597284.039172.6384ficedula_albicollisENSFALP0000002024384.313772.8758
ENSG00000108829homo_sapiensENSP0000022597284.039171.0098coturnix_japonicaENSCJPP0000502784971.866360.7242
ENSG00000108829homo_sapiensENSP0000022597270.68453.0945leptobrachium_leishanenseENSLLEP0000004513970.68453.0945

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005635located_in nuclear envelope1IEAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm1IBAHomo_sapiens(9606)Component
GO:0005783located_in endoplasmic reticulum1IDAHomo_sapiens(9606)Component
GO:0005789located_in endoplasmic reticulum membrane1IEAHomo_sapiens(9606)Component
GO:0007165involved_in signal transduction1IBAHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0042645located_in mitochondrial nucleoid1IDAHomo_sapiens(9606)Component
GO:0043231is_active_in intracellular membrane-bounded organelle1IBAHomo_sapiens(9606)Component
GO:0045296enables cadherin binding1HDAHomo_sapiens(9606)Function

Expression