RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	TF
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000108511	Gene ID	3216	Accession	5117
Symbol	HOXB6	Alias	HOX2;HU-2;HOX2B;Hox-2.2	Full Name	homeobox B6
Status	Confidence	Length	9242 bases	Strand	Minus strand
Position	17 : 48595751 - 48604992	RNA binding domain	N.A.
Summary	This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer. [provided by RefSeq, Jul 2008]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
HOXB6-201	ENST00000225648	1676	224aa	ENSP00000225648
HOXB6-203	ENST00000484302	1960	224aa	ENSP00000420009
HOXB6-202	ENST00000470193	371	No protein	-
HOXB6-204	ENST00000490419	468	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
37257	Platelet Function Tests	3.0124000E-005	-
39596	Platelet Function Tests	2.0536700E-005	-
83622	Body Mass Index	2E-6	26604143

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000785	part_of chromatin	1	ISA	Homo_sapiens(9606)	Component
GO:0000978	enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	1	IBA	Homo_sapiens(9606)	Function
GO:0000981	enables DNA-binding transcription factor activity, RNA polymerase II-specific	2	IBA,ISA	Homo_sapiens(9606)	Function
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	1	IBA	Homo_sapiens(9606)	Component
GO:0006357	involved_in regulation of transcription by RNA polymerase II	1	IBA	Homo_sapiens(9606)	Process
GO:0009952	involved_in anterior/posterior pattern specification	1	IBA	Homo_sapiens(9606)	Process
GO:0034101	involved_in erythrocyte homeostasis	1	IEA	Homo_sapiens(9606)	Process
GO:0048704	involved_in embryonic skeletal system morphogenesis	1	IEA	Homo_sapiens(9606)	Process
GO:1990837	enables sequence-specific double-stranded DNA binding	1	IDA	Homo_sapiens(9606)	Function