RBP Type	Canonical_RBPs
Diseases	CancerSARS-COV-2
Drug	N.A.
Main interacting RNAs	rRNA
Moonlighting functions	N.A.
Localizations	Stress granucleP-bodyNucleoli
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000107625	Gene ID	79009	Accession	17906
Symbol	DDX50	Alias	GU2;GUB;mcdrh;RH-II/GuB	Full Name	DExD-box helicase 50
Status	Confidence	Length	45562 bases	Strand	Plus strand
Position	10 : 68901286 - 68946847	RNA binding domain	ResIII , DEAD , GUCT
Summary	DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box enzyme that may be involved in ribosomal RNA synthesis or processing. This gene and DDX21, also called RH-II/GuA, have similar genomic structures and are in tandem orientation on chromosome 10, suggesting that the two genes arose by gene duplication in evolution. This gene has pseudogenes on chromosomes 2, 3 and 4. Alternative splicing of this gene generates multiple transcript variants, but the full length nature of all the other variants but one has not been defined. [provided by RefSeq, Jul 2008]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000362687	DEAD	PF00270	7.5e-47	1
ENSP00000362687	ResIII	PF04851	1.6e-09	2
ENSP00000362687	GUCT	PF08152	7.4e-27	3

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
35215908	DDX50 Is a Viral Restriction Factor That Enhances IRF3 Activation.	A Mitchell Pallett	2022-02-03	Viruses
33692367	easyCLIP analysis of RNA-protein interactions incorporating absolute quantification.	F Douglas Porter	2021-03-10	Nature communications

Name	Transcript ID	bp	Protein	Translation ID
DDX50-205	ENST00000483593	1067	39aa	ENSP00000474785
DDX50-201	ENST00000373585	2501	737aa	ENSP00000362687
DDX50-204	ENST00000471475	888	51aa	ENSP00000474314
DDX50-202	ENST00000460470	531	No protein	-
DDX50-203	ENST00000466265	744	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
77646	Depressive Disorder	9E-6	20800221

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000107625	homo_sapiens	ENSP00000379475	50.2336	25.7009	homo_sapiens	ENSP00000362687	29.1723	14.9254
ENSG00000107625	homo_sapiens	ENSP00000385536	33.4705	19.0672	homo_sapiens	ENSP00000362687	33.1072	18.8602
ENSG00000107625	homo_sapiens	ENSP00000263239	38.9552	22.0896	homo_sapiens	ENSP00000362687	35.4138	20.0814
ENSG00000107625	homo_sapiens	ENSP00000497641	49.635	29.927	homo_sapiens	ENSP00000362687	27.6798	16.6893
ENSG00000107625	homo_sapiens	ENSP00000482680	33.0719	19.6078	homo_sapiens	ENSP00000362687	34.3284	20.3528
ENSG00000107625	homo_sapiens	ENSP00000293831	50.4926	31.2808	homo_sapiens	ENSP00000362687	27.8155	17.232
ENSG00000107625	homo_sapiens	ENSP00000306117	44.3515	24.477	homo_sapiens	ENSP00000362687	28.7653	15.8752
ENSG00000107625	homo_sapiens	ENSP00000288071	44.2589	24.4259	homo_sapiens	ENSP00000362687	28.7653	15.8752
ENSG00000107625	homo_sapiens	ENSP00000481495	28.8708	16.6473	homo_sapiens	ENSP00000362687	33.6499	19.403
ENSG00000107625	homo_sapiens	ENSP00000416534	25.3876	14.5349	homo_sapiens	ENSP00000362687	35.5495	20.3528
ENSG00000107625	homo_sapiens	ENSP00000361232	31.5013	17.6944	homo_sapiens	ENSP00000362687	31.886	17.9104
ENSG00000107625	homo_sapiens	ENSP00000492643	16.7669	8.87218	homo_sapiens	ENSP00000362687	30.2578	16.0109
ENSG00000107625	homo_sapiens	ENSP00000238146	35.6667	20.6667	homo_sapiens	ENSP00000362687	29.0366	16.825
ENSG00000107625	homo_sapiens	ENSP00000225792	39.7394	23.2899	homo_sapiens	ENSP00000362687	33.1072	19.403
ENSG00000107625	homo_sapiens	ENSP00000368667	35.8162	20.1268	homo_sapiens	ENSP00000362687	30.6649	17.232
ENSG00000107625	homo_sapiens	ENSP00000330460	38.2876	19.8708	homo_sapiens	ENSP00000362687	32.1574	16.6893
ENSG00000107625	homo_sapiens	ENSP00000263576	41.4079	23.1884	homo_sapiens	ENSP00000362687	27.137	15.1967
ENSG00000107625	homo_sapiens	ENSP00000380495	34.0841	17.8679	homo_sapiens	ENSP00000362687	30.8005	16.1465
ENSG00000107625	homo_sapiens	ENSP00000314348	27.7714	15.4286	homo_sapiens	ENSP00000362687	32.9715	18.3175
ENSG00000107625	homo_sapiens	ENSP00000346120	68.1992	56.1941	homo_sapiens	ENSP00000362687	72.4559	59.7015
ENSG00000107625	homo_sapiens	ENSP00000374574	27.5053	16.6311	homo_sapiens	ENSP00000362687	35.0068	21.1669
ENSG00000107625	homo_sapiens	ENSP00000358716	27.5485	15.2913	homo_sapiens	ENSP00000362687	30.8005	17.0963
ENSG00000107625	homo_sapiens	ENSP00000442266	41.4079	23.8095	homo_sapiens	ENSP00000362687	27.137	15.6038
ENSG00000107625	homo_sapiens	ENSP00000479504	36.5609	20.3673	homo_sapiens	ENSP00000362687	29.7151	16.5536
ENSG00000107625	homo_sapiens	ENSP00000359361	37.1914	22.9938	homo_sapiens	ENSP00000362687	32.7001	20.2171
ENSG00000107625	homo_sapiens	ENSP00000326381	50.6143	32.1867	homo_sapiens	ENSP00000362687	27.9512	17.7748
ENSG00000107625	homo_sapiens	ENSP00000258772	37.8428	21.5722	homo_sapiens	ENSP00000362687	28.0868	16.0109
ENSG00000107625	homo_sapiens	ENSP00000494040	38.3686	22.8097	homo_sapiens	ENSP00000362687	34.464	20.4885
ENSG00000107625	homo_sapiens	ENSP00000336725	38.0303	22.8788	homo_sapiens	ENSP00000362687	34.057	20.4885
ENSG00000107625	homo_sapiens	ENSP00000247003	42.236	24.4306	homo_sapiens	ENSP00000362687	27.6798	16.0109
ENSG00000107625	homo_sapiens	ENSP00000330349	39.8714	23.6334	homo_sapiens	ENSP00000362687	33.6499	19.9457
ENSG00000107625	homo_sapiens	ENSP00000242776	50.5855	25.7611	homo_sapiens	ENSP00000362687	29.308	14.9254
ENSG00000107625	homo_sapiens	ENSP00000233084	30.9459	18.2432	homo_sapiens	ENSP00000362687	31.0719	18.3175
ENSG00000107625	homo_sapiens	ENSP00000304072	29.8524	16.5721	homo_sapiens	ENSP00000362687	35.6852	19.81
ENSG00000107625	homo_sapiens	ENSP00000350698	46.8132	28.1319	homo_sapiens	ENSP00000362687	28.9009	17.3677
ENSG00000107625	homo_sapiens	ENSP00000310723	28.6585	17.1951	homo_sapiens	ENSP00000362687	31.886	19.1316
ENSG00000107625	homo_sapiens	ENSP00000332340	37.963	20.7407	homo_sapiens	ENSP00000362687	27.8155	15.1967
ENSG00000107625	homo_sapiens	ENSP00000424838	32.8729	19.8895	homo_sapiens	ENSP00000362687	32.2931	19.5387

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000107625	homo_sapiens	ENSP00000362687	100	99.8643	nomascus_leucogenys	ENSNLEP00000014191	100	99.8643
ENSG00000107625	homo_sapiens	ENSP00000362687	100	99.8643	pan_paniscus	ENSPPAP00000035895	100	99.8643
ENSG00000107625	homo_sapiens	ENSP00000362687	100	100	pongo_abelii	ENSPPYP00000002775	100	100
ENSG00000107625	homo_sapiens	ENSP00000362687	100	99.8643	pan_troglodytes	ENSPTRP00000059960	100	99.8643
ENSG00000107625	homo_sapiens	ENSP00000362687	100	100	gorilla_gorilla	ENSGGOP00000018967	100	100
ENSG00000107625	homo_sapiens	ENSP00000362687	87.3813	79.5115	sarcophilus_harrisii	ENSSHAP00000006538	86.7924	78.9757
ENSG00000107625	homo_sapiens	ENSP00000362687	87.924	86.2958	choloepus_hoffmanni	ENSCHOP00000000202	98.0333	96.2178
ENSG00000107625	homo_sapiens	ENSP00000362687	83.8535	79.9186	dasypus_novemcinctus	ENSDNOP00000001299	95.6656	91.1765
ENSG00000107625	homo_sapiens	ENSP00000362687	86.9742	85.2103	erinaceus_europaeus	ENSEEUP00000005300	87.2109	85.4422
ENSG00000107625	homo_sapiens	ENSP00000362687	88.4668	86.4315	echinops_telfairi	ENSETEP00000011421	88.8283	86.7847
ENSG00000107625	homo_sapiens	ENSP00000362687	100	99.7286	callithrix_jacchus	ENSCJAP00000035086	100	99.7286
ENSG00000107625	homo_sapiens	ENSP00000362687	97.422	96.4722	cercocebus_atys	ENSCATP00000017159	98.6264	97.6648
ENSG00000107625	homo_sapiens	ENSP00000362687	91.1805	91.0448	macaca_fascicularis	ENSMFAP00000025094	100	99.8512
ENSG00000107625	homo_sapiens	ENSP00000362687	100	99.7286	macaca_mulatta	ENSMMUP00000001350	100	99.7286
ENSG00000107625	homo_sapiens	ENSP00000362687	93.6228	93.3514	macaca_nemestrina	ENSMNEP00000015168	97.5955	97.3126
ENSG00000107625	homo_sapiens	ENSP00000362687	97.9647	97.5577	mandrillus_leucophaeus	ENSMLEP00000026372	99.0398	98.6283
ENSG00000107625	homo_sapiens	ENSP00000362687	92.1303	91.1805	tursiops_truncatus	ENSTTRP00000011778	92.2554	91.3043
ENSG00000107625	homo_sapiens	ENSP00000362687	77.0692	75.3053	vulpes_vulpes	ENSVVUP00000027935	94.3522	92.1927
ENSG00000107625	homo_sapiens	ENSP00000362687	97.6934	95.6581	mus_spretus	MGP_SPRETEiJ_P0024279	98.0926	96.049
ENSG00000107625	homo_sapiens	ENSP00000362687	89.9593	89.4166	equus_asinus	ENSEASP00005022873	98.6607	98.0655
ENSG00000107625	homo_sapiens	ENSP00000362687	98.7788	97.1506	capra_hircus	ENSCHIP00000000400	98.645	97.019
ENSG00000107625	homo_sapiens	ENSP00000362687	98.9145	97.9647	loxodonta_africana	ENSLAFP00000005192	99.3188	98.3651
ENSG00000107625	homo_sapiens	ENSP00000362687	99.3216	98.3718	panthera_leo	ENSPLOP00000023972	99.0528	98.1055
ENSG00000107625	homo_sapiens	ENSP00000362687	98.7788	97.5577	ailuropoda_melanoleuca	ENSAMEP00000019012	98.5115	97.2936
ENSG00000107625	homo_sapiens	ENSP00000362687	90.502	89.1452	bos_indicus_hybrid	ENSBIXP00005014857	99.256	97.7679
ENSG00000107625	homo_sapiens	ENSP00000362687	97.6934	95.7938	oryctolagus_cuniculus	ENSOCUP00000018368	97.9592	96.0544
ENSG00000107625	homo_sapiens	ENSP00000362687	91.5875	90.9091	equus_caballus	ENSECAP00000020644	98.1105	97.3837
ENSG00000107625	homo_sapiens	ENSP00000362687	99.3216	97.9647	canis_lupus_familiaris	ENSCAFP00845004191	99.0528	97.6996
ENSG00000107625	homo_sapiens	ENSP00000362687	99.3216	98.3718	panthera_pardus	ENSPPRP00000025508	99.187	98.2385
ENSG00000107625	homo_sapiens	ENSP00000362687	99.3216	97.6934	marmota_marmota_marmota	ENSMMMP00000010408	99.0528	97.429
ENSG00000107625	homo_sapiens	ENSP00000362687	18.1818	17.3677	balaenoptera_musculus	ENSBMSP00010019256	95.0355	90.7801
ENSG00000107625	homo_sapiens	ENSP00000362687	97.9647	96.6079	cavia_porcellus	ENSCPOP00000001929	98.2313	96.8708
ENSG00000107625	homo_sapiens	ENSP00000362687	99.3216	98.3718	felis_catus	ENSFCAP00000023971	99.0528	98.1055
ENSG00000107625	homo_sapiens	ENSP00000362687	98.9145	97.829	ursus_americanus	ENSUAMP00000014620	98.7805	97.6965
ENSG00000107625	homo_sapiens	ENSP00000362687	87.6526	80.7327	monodelphis_domestica	ENSMODP00000013458	86.7114	79.8658
ENSG00000107625	homo_sapiens	ENSP00000362687	99.1859	97.422	bison_bison_bison	ENSBBBP00000027218	99.1859	97.422
ENSG00000107625	homo_sapiens	ENSP00000362687	98.7788	97.6934	monodon_monoceros	ENSMMNP00015024426	98.3784	97.2973
ENSG00000107625	homo_sapiens	ENSP00000362687	96.6079	94.7083	sus_scrofa	ENSSSCP00000010924	98.4786	96.5422
ENSG00000107625	homo_sapiens	ENSP00000362687	91.9946	90.7734	microcebus_murinus	ENSMICP00000015973	99.2679	97.9502
ENSG00000107625	homo_sapiens	ENSP00000362687	98.5075	96.4722	octodon_degus	ENSODEP00000019768	98.6413	96.6033
ENSG00000107625	homo_sapiens	ENSP00000362687	97.5577	94.9796	jaculus_jaculus	ENSJJAP00000024483	97.6902	95.1087
ENSG00000107625	homo_sapiens	ENSP00000362687	76.2551	73.9484	jaculus_jaculus	ENSJJAP00000018342	91.3821	88.6179
ENSG00000107625	homo_sapiens	ENSP00000362687	98.6432	97.1506	ovis_aries_rambouillet	ENSOARP00020012290	98.6432	97.1506
ENSG00000107625	homo_sapiens	ENSP00000362687	98.9145	97.829	ursus_maritimus	ENSUMAP00000010278	98.6468	97.5643
ENSG00000107625	homo_sapiens	ENSP00000362687	97.2863	94.3012	ochotona_princeps	ENSOPRP00000001493	97.8172	94.8158
ENSG00000107625	homo_sapiens	ENSP00000362687	90.7734	89.6879	delphinapterus_leucas	ENSDLEP00000012007	98.3824	97.2059
ENSG00000107625	homo_sapiens	ENSP00000362687	98.7788	97.2863	physeter_catodon	ENSPCTP00005008941	98.645	97.1545
ENSG00000107625	homo_sapiens	ENSP00000362687	97.5577	95.251	mus_caroli	MGP_CAROLIEiJ_P0023134	97.9564	95.6403
ENSG00000107625	homo_sapiens	ENSP00000362687	97.6934	95.6581	mus_musculus	ENSMUSP00000020270	98.0926	96.049
ENSG00000107625	homo_sapiens	ENSP00000362687	99.0502	97.2863	dipodomys_ordii	ENSDORP00000006854	99.0502	97.2863
ENSG00000107625	homo_sapiens	ENSP00000362687	86.7029	85.346	mustela_putorius_furo	ENSMPUP00000004554	98.6111	97.0679
ENSG00000107625	homo_sapiens	ENSP00000362687	84.9389	82.0896	aotus_nancymaae	ENSANAP00000002277	90.7246	87.6812
ENSG00000107625	homo_sapiens	ENSP00000362687	90.502	90.2307	saimiri_boliviensis_boliviensis	ENSSBOP00000002836	99.8503	99.5509
ENSG00000107625	homo_sapiens	ENSP00000362687	98.5075	97.2863	vicugna_pacos	ENSVPAP00000000579	98.5075	97.2863
ENSG00000107625	homo_sapiens	ENSP00000362687	100	99.7286	chlorocebus_sabaeus	ENSCSAP00000003936	100	99.7286
ENSG00000107625	homo_sapiens	ENSP00000362687	77.6119	76.3908	tupaia_belangeri	ENSTBEP00000000950	77.6119	76.3908
ENSG00000107625	homo_sapiens	ENSP00000362687	44.2334	43.0122	mesocricetus_auratus	ENSMAUP00000000109	96.7359	94.0653
ENSG00000107625	homo_sapiens	ENSP00000362687	44.2334	43.0122	mesocricetus_auratus	ENSMAUP00000011259	96.7359	94.0653
ENSG00000107625	homo_sapiens	ENSP00000362687	98.7788	97.829	phocoena_sinus	ENSPSNP00000025860	98.2456	97.3009
ENSG00000107625	homo_sapiens	ENSP00000362687	98.6432	97.5577	camelus_dromedarius	ENSCDRP00005025729	98.5095	97.4255
ENSG00000107625	homo_sapiens	ENSP00000362687	99.5929	98.3718	carlito_syrichta	ENSTSYP00000003845	99.5929	98.3718
ENSG00000107625	homo_sapiens	ENSP00000362687	99.3216	98.3718	panthera_tigris_altaica	ENSPTIP00000006597	99.187	98.2385
ENSG00000107625	homo_sapiens	ENSP00000362687	97.6934	95.251	rattus_norvegicus	ENSRNOP00000097507	98.0926	95.6403
ENSG00000107625	homo_sapiens	ENSP00000362687	99.3216	98.3718	prolemur_simus	ENSPSMP00000013315	99.3216	98.3718
ENSG00000107625	homo_sapiens	ENSP00000362687	98.1004	95.9294	microtus_ochrogaster	ENSMOCP00000002131	97.9675	95.7995
ENSG00000107625	homo_sapiens	ENSP00000362687	83.5821	81.9539	sorex_araneus	ENSSARP00000012243	83.9237	82.2888
ENSG00000107625	homo_sapiens	ENSP00000362687	95.5224	92.2659	peromyscus_maniculatus_bairdii	ENSPEMP00000033145	95.0067	91.7679
ENSG00000107625	homo_sapiens	ENSP00000362687	99.1859	97.422	bos_mutus	ENSBMUP00000030251	99.1859	97.422
ENSG00000107625	homo_sapiens	ENSP00000362687	97.5577	95.5224	mus_spicilegus	ENSMSIP00000036560	97.9564	95.9128
ENSG00000107625	homo_sapiens	ENSP00000362687	98.3718	96.0651	cricetulus_griseus_chok1gshd	ENSCGRP00001021348	98.5054	96.1957
ENSG00000107625	homo_sapiens	ENSP00000362687	77.4763	76.2551	pteropus_vampyrus	ENSPVAP00000008968	77.5815	76.3587
ENSG00000107625	homo_sapiens	ENSP00000362687	98.2361	96.3365	myotis_lucifugus	ENSMLUP00000016041	98.7722	96.8622
ENSG00000107625	homo_sapiens	ENSP00000362687	87.2456	78.9688	vombatus_ursinus	ENSVURP00010019870	82.9677	75.0968
ENSG00000107625	homo_sapiens	ENSP00000362687	99.0502	97.829	neovison_vison	ENSNVIP00000015924	98.7821	97.5643
ENSG00000107625	homo_sapiens	ENSP00000362687	99.1859	97.422	bos_taurus	ENSBTAP00000022002	99.1859	97.422
ENSG00000107625	homo_sapiens	ENSP00000362687	97.6934	95.9294	heterocephalus_glaber_female	ENSHGLP00000018797	97.6934	95.9294
ENSG00000107625	homo_sapiens	ENSP00000362687	99.3216	97.9647	canis_lupus_dingo	ENSCAFP00020033457	99.0528	97.6996
ENSG00000107625	homo_sapiens	ENSP00000362687	99.3216	97.9647	sciurus_vulgaris	ENSSVLP00005005029	99.187	97.832
ENSG00000107625	homo_sapiens	ENSP00000362687	87.517	79.3758	phascolarctos_cinereus	ENSPCIP00000021116	86.4611	78.4182
ENSG00000107625	homo_sapiens	ENSP00000362687	70.692	70.1493	procavia_capensis	ENSPCAP00000009048	84.9918	84.3393
ENSG00000107625	homo_sapiens	ENSP00000362687	98.5075	96.8792	nannospalax_galili	ENSNGAP00000003635	98.7755	97.1429
ENSG00000107625	homo_sapiens	ENSP00000362687	99.1859	97.422	bos_grunniens	ENSBGRP00000016663	99.1859	97.422
ENSG00000107625	homo_sapiens	ENSP00000362687	98.7788	97.829	chinchilla_lanigera	ENSCLAP00000018920	98.913	97.962
ENSG00000107625	homo_sapiens	ENSP00000362687	73.8128	69.6065	chinchilla_lanigera	ENSCLAP00000002686	90.5158	85.3577
ENSG00000107625	homo_sapiens	ENSP00000362687	45.5902	44.5047	chinchilla_lanigera	ENSCLAP00000002140	90.566	88.4097
ENSG00000107625	homo_sapiens	ENSP00000362687	91.1805	89.0095	catagonus_wagneri	ENSCWAP00000028800	97.6744	95.3488
ENSG00000107625	homo_sapiens	ENSP00000362687	97.829	96.0651	ictidomys_tridecemlineatus	ENSSTOP00000021892	98.3629	96.5894
ENSG00000107625	homo_sapiens	ENSP00000362687	99.4573	98.3718	otolemur_garnettii	ENSOGAP00000001642	99.4573	98.3718
ENSG00000107625	homo_sapiens	ENSP00000362687	81.8182	78.5617	cebus_imitator	ENSCCAP00000025554	91.0876	87.4622
ENSG00000107625	homo_sapiens	ENSP00000362687	99.3216	97.829	urocitellus_parryii	ENSUPAP00010010658	99.187	97.6965
ENSG00000107625	homo_sapiens	ENSP00000362687	98.7788	97.829	moschus_moschiferus	ENSMMSP00000031175	98.645	97.6965
ENSG00000107625	homo_sapiens	ENSP00000362687	99.8643	99.4573	rhinopithecus_roxellana	ENSRROP00000016010	99.8643	99.4573
ENSG00000107625	homo_sapiens	ENSP00000362687	97.829	95.7938	mus_pahari	MGP_PahariEiJ_P0086305	98.2289	96.1853
ENSG00000107625	homo_sapiens	ENSP00000362687	72.4559	69.7422	propithecus_coquereli	ENSPCOP00000004300	89.7479	86.3866
ENSG00000107625	homo_sapiens	ENSP00000362687	72.0488	57.9376	oryzias_javanicus	ENSOJAP00000044388	68.3398	54.955

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0003723	enables RNA binding	2	HDA,IBA	Homo_sapiens(9606)	Function
GO:0003724	enables RNA helicase activity	1	IBA	Homo_sapiens(9606)	Function
GO:0005524	enables ATP binding	1	IEA	Homo_sapiens(9606)	Function
GO:0005730	is_active_in nucleolus	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005886	located_in plasma membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0016020	located_in membrane	1	HDA	Homo_sapiens(9606)	Component
GO:0016887	enables ATP hydrolysis activity	1	IEA	Homo_sapiens(9606)	Function