Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs diverse
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000107371 Gene ID 51010 Accession 17944
Symbol EXOSC3 Alias p10;PCH1B;RRP40;Rrp40p;CGI-102;hRrp-40;bA3J10.7 Full Name exosome component 3
Status Confidence Length 72884 bases Strand Minus strand
Position 9 : 37759234 - 37832117 RNA binding domain KH_6
Summary This gene encodes a non-catalytic component of the human exosome, a complex with 3'-5' exoribonuclease activity that plays a role in numerous RNA processing and degradation activities. Related pseudogenes of this gene are found on chromosome 19 and 21. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2012]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000323046 KH_6 PF15985 3.1e-14 1
ENSP00000503205 KH_6 PF15985 4.1e-09 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
29093021 The RNA exosome and RNA exosome-linked disease. J Derrick Morton 2018-02-01 RNA (New York, N.Y.)
27881476 Lin28a uses distinct mechanisms of binding to RNA and affects miRNA levels positively and negatively. Stanislaw Jakub Nowak 2017-03-01 RNA (New York, N.Y.)
29903031 What's new in pontocerebellar hypoplasia? An update on genes and subtypes. Tessa T van 2018-06-15 Orphanet journal of rare diseases
30141626 A Chemical Biology Approach to Model Pontocerebellar Hypoplasia Type 1B (PCH1B). Liberty François-Moutal 2018-10-19 ACS chemical biology
34626022 Aberrant expression of MYD88 via RNA-controlling CNOT4 and EXOSC3 in colonic mucosa impacts generation of colonic cancer. Masumi Tsuda 2021-12-01 Cancer science
32645003 A Drosophila model of Pontocerebellar Hypoplasia reveals a critical role for the RNA exosome in neurons. J Derrick Morton 2020-07-01 PLoS genetics
36161469 RNA-regulatory exosome complex suppresses an apoptotic program to confer erythroid progenitor cell survival in vivo. Isabela I Andrade Fraga 2023-02-28 Blood advances
28053271 Mutations of EXOSC3/Rrp40p associated with neurological diseases impact ribosomal RNA processing functions of the exosome in S. cerevisiae. Abby Gillespie 2017-04-01 RNA (New York, N.Y.)
27193168 Altered RNA metabolism due to a homozygous RBM7 mutation in a patient with spinal motor neuropathy. Michele Giunta 2016-07-15 Human molecular genetics

Transcripts

Name Transcript ID bp Protein Translation ID
EXOSC3-209 ENST00000678095 3540 93aa ENSP00000503205
EXOSC3-211 ENST00000679059 3356 164aa ENSP00000503947
EXOSC3-203 ENST00000465229 1625 164aa ENSP00000418422
EXOSC3-201 ENST00000327304 1813 275aa ENSP00000323046
EXOSC3-204 ENST00000465860 2253 No protein -
EXOSC3-207 ENST00000490516 773 No protein -
EXOSC3-202 ENST00000396521 768 164aa ENSP00000379775
EXOSC3-206 ENST00000489414 535 No protein -
EXOSC3-205 ENST00000482614 462 No protein -
EXOSC3-210 ENST00000678588 2012 No protein -
EXOSC3-208 ENST00000496910 217 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
15726Stroke8.0893775E-004-
22264Glucose3.637e-005-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000107371homo_sapiensENSP0000036143333.788419.4539homo_sapiensENSP000003230463620.7273

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000107371homo_sapiensENSP0000032304697.818297.4545nomascus_leucogenysENSNLEP0000000427097.818297.4545
ENSG00000107371homo_sapiensENSP0000032304699.272799.2727pan_paniscusENSPPAP0000001343499.272799.2727
ENSG00000107371homo_sapiensENSP0000032304698.909198.9091pongo_abeliiENSPPYP0000002135698.909198.9091
ENSG00000107371homo_sapiensENSP0000032304699.272799.2727pan_troglodytesENSPTRP0000003583699.272799.2727
ENSG00000107371homo_sapiensENSP0000032304699.272799.2727gorilla_gorillaENSGGOP0000003879499.272799.2727
ENSG00000107371homo_sapiensENSP000003230467668ornithorhynchus_anatinusENSOANP0000003545970.134262.7517
ENSG00000107371homo_sapiensENSP0000032304689.454584sarcophilus_harrisiiENSSHAP0000003351491.111185.5556
ENSG00000107371homo_sapiensENSP0000032304675.272771.2727notamacropus_eugeniiENSMEUP0000000703197.641592.4528
ENSG00000107371homo_sapiensENSP0000032304694.545593.0909choloepus_hoffmanniENSCHOP0000000213695.588294.1176
ENSG00000107371homo_sapiensENSP0000032304695.272793.0909dasypus_novemcinctusENSDNOP0000002515395.272793.0909
ENSG00000107371homo_sapiensENSP0000032304669.818268erinaceus_europaeusENSEEUP0000001328695.049592.5743
ENSG00000107371homo_sapiensENSP0000032304694.181890.5455echinops_telfairiENSETEP0000001480494.525690.8759
ENSG00000107371homo_sapiensENSP0000032304696.363695.6364callithrix_jacchusENSCJAP0000001954795.667994.9458
ENSG00000107371homo_sapiensENSP0000032304697.818297.8182cercocebus_atysENSCATP0000004280997.818297.8182
ENSG00000107371homo_sapiensENSP0000032304698.181898.1818macaca_fascicularisENSMFAP0000000408898.181898.1818
ENSG00000107371homo_sapiensENSP0000032304698.181898.1818macaca_mulattaENSMMUP0000004182598.181898.1818
ENSG00000107371homo_sapiensENSP0000032304698.181898.1818macaca_nemestrinaENSMNEP0000002736798.181898.1818
ENSG00000107371homo_sapiensENSP0000032304698.181897.8182papio_anubisENSPANP0000001907198.181897.8182
ENSG00000107371homo_sapiensENSP0000032304697.454597.4545mandrillus_leucophaeusENSMLEP0000001849397.454597.4545
ENSG00000107371homo_sapiensENSP0000032304695.272793.0909tursiops_truncatusENSTTRP0000001117195.272793.0909
ENSG00000107371homo_sapiensENSP0000032304694.545593.0909vulpes_vulpesENSVVUP0000002706194.545593.0909
ENSG00000107371homo_sapiensENSP0000032304691.636486.9091mus_spretusMGP_SPRETEiJ_P006466890.974786.2816
ENSG00000107371homo_sapiensENSP0000032304696.727394.5455equus_asinusENSEASP0000505194096.727394.5455
ENSG00000107371homo_sapiensENSP000003230469694.5455capra_hircusENSCHIP000000194629694.5455
ENSG00000107371homo_sapiensENSP0000032304696.363694.1818loxodonta_africanaENSLAFP0000000060496.014593.8406
ENSG00000107371homo_sapiensENSP0000032304694.909192.7273panthera_leoENSPLOP0000001367473.521171.831
ENSG00000107371homo_sapiensENSP0000032304695.272793.8182ailuropoda_melanoleucaENSAMEP0000003670995.272793.8182
ENSG00000107371homo_sapiensENSP000003230469694.1818bos_indicus_hybridENSBIXP000050015509694.1818
ENSG00000107371homo_sapiensENSP0000032304691.636489.0909oryctolagus_cuniculusENSOCUP0000000311971.388169.4051
ENSG00000107371homo_sapiensENSP0000032304696.727394.1818equus_caballusENSECAP0000003067996.727394.1818
ENSG00000107371homo_sapiensENSP0000032304673.818268canis_lupus_familiarisENSCAFP0084501959662.079557.1865
ENSG00000107371homo_sapiensENSP0000032304694.545592.3636panthera_pardusENSPPRP0000001649894.890592.7007
ENSG00000107371homo_sapiensENSP0000032304694.545592.3636marmota_marmota_marmotaENSMMMP0000000624394.545592.3636
ENSG00000107371homo_sapiensENSP0000032304694.909193.0909balaenoptera_musculusENSBMSP0001000817494.909193.0909
ENSG00000107371homo_sapiensENSP0000032304694.181890.5455cavia_porcellusENSCPOP0000000775694.181890.5455
ENSG00000107371homo_sapiensENSP0000032304695.272793.0909felis_catusENSFCAP0000003020758.222256.8889
ENSG00000107371homo_sapiensENSP0000032304694.909193.4545ursus_americanusENSUAMP0000000561094.909193.4545
ENSG00000107371homo_sapiensENSP0000032304688.363683.6364monodelphis_domesticaENSMODP0000000361488.363683.6364
ENSG00000107371homo_sapiensENSP000003230469694.1818bison_bison_bisonENSBBBP0000002388495.652293.8406
ENSG00000107371homo_sapiensENSP0000032304694.909193.0909monodon_monocerosENSMMNP0001501842094.909193.0909
ENSG00000107371homo_sapiensENSP0000032304694.909192sus_scrofaENSSSCP0000000574894.909192
ENSG00000107371homo_sapiensENSP0000032304696.727395.6364microcebus_murinusENSMICP0000002975796.727395.6364
ENSG00000107371homo_sapiensENSP0000032304694.909192octodon_degusENSODEP0000002021294.909192
ENSG00000107371homo_sapiensENSP0000032304681.454577.0909octodon_degusENSODEP0000000005885.823881.2261
ENSG00000107371homo_sapiensENSP000003230469694.5455ovis_aries_rambouilletENSOARP0002000265795.652294.2029
ENSG00000107371homo_sapiensENSP0000032304693.818292.3636ursus_maritimusENSUMAP0000001576493.818292.3636
ENSG00000107371homo_sapiensENSP0000032304668.727368ochotona_princepsENSOPRP0000001306795.454594.4444
ENSG00000107371homo_sapiensENSP0000032304694.545592.7273delphinapterus_leucasENSDLEP0000002045194.890593.0657
ENSG00000107371homo_sapiensENSP0000032304695.272793.0909physeter_catodonENSPCTP0000502128695.272793.0909
ENSG00000107371homo_sapiensENSP0000032304691.636486.1818mus_caroliMGP_CAROLIEiJ_P006219791.970886.4964
ENSG00000107371homo_sapiensENSP0000032304691.636486.9091mus_musculusENSMUSP0000003000391.970887.2263
ENSG00000107371homo_sapiensENSP000003230469290.1818dipodomys_ordiiENSDORP000000135119290.1818
ENSG00000107371homo_sapiensENSP0000032304694.545592mustela_putorius_furoENSMPUP0000000609294.202991.6667
ENSG00000107371homo_sapiensENSP0000032304696.727396.3636aotus_nancymaaeENSANAP0000002295996.727396.3636
ENSG00000107371homo_sapiensENSP0000032304696.363695.6364saimiri_boliviensis_boliviensisENSSBOP0000003878496.014595.2899
ENSG00000107371homo_sapiensENSP0000032304694.181892.3636vicugna_pacosENSVPAP0000000842694.525692.7007
ENSG00000107371homo_sapiensENSP0000032304698.181897.8182chlorocebus_sabaeusENSCSAP0000000703098.181897.8182
ENSG00000107371homo_sapiensENSP0000032304694.545592.3636tupaia_belangeriENSTBEP0000001300595.238193.0403
ENSG00000107371homo_sapiensENSP0000032304692.727388mesocricetus_auratusENSMAUP0000000682193.065788.3212
ENSG00000107371homo_sapiensENSP0000032304694.909193.0909phocoena_sinusENSPSNP0000001695494.909193.0909
ENSG00000107371homo_sapiensENSP0000032304694.545592.7273camelus_dromedariusENSCDRP0000500128594.890593.0657
ENSG00000107371homo_sapiensENSP0000032304696.363693.4545carlito_syrichtaENSTSYP0000001252896.363693.4545
ENSG00000107371homo_sapiensENSP0000032304694.909192.3636panthera_tigris_altaicaENSPTIP0000001826995.255592.7007
ENSG00000107371homo_sapiensENSP000003230469286.9091rattus_norvegicusENSRNOP0000001658288.153383.2753
ENSG00000107371homo_sapiensENSP0000032304695.636494.9091prolemur_simusENSPSMP0000000733994.945894.2238
ENSG00000107371homo_sapiensENSP0000032304691.636486.5455microtus_ochrogasterENSMOCP0000002041791.970886.8613
ENSG00000107371homo_sapiensENSP0000032304693.090988.3636peromyscus_maniculatus_bairdiiENSPEMP0000001911693.430788.6861
ENSG00000107371homo_sapiensENSP000003230469694.1818bos_mutusENSBMUP000000028329694.1818
ENSG00000107371homo_sapiensENSP0000032304691.636486.9091mus_spicilegusENSMSIP0000002388690.322685.6631
ENSG00000107371homo_sapiensENSP0000032304692.363688cricetulus_griseus_chok1gshdENSCGRP0000100166689.752685.5124
ENSG00000107371homo_sapiensENSP0000032304645.454545.0909pteropus_vampyrusENSPVAP0000000972659.808659.3301
ENSG00000107371homo_sapiensENSP0000032304647.636444myotis_lucifugusENSMLUP0000001927978.443172.4551
ENSG00000107371homo_sapiensENSP0000032304689.454583.2727vombatus_ursinusENSVURP0001001526190.109983.8828
ENSG00000107371homo_sapiensENSP0000032304696.363693.8182rhinolophus_ferrumequinumENSRFEP0001002628696.363693.8182
ENSG00000107371homo_sapiensENSP0000032304694.545592.3636neovison_visonENSNVIP0000002017394.202992.029
ENSG00000107371homo_sapiensENSP000003230469694.1818bos_taurusENSBTAP000000251859694.1818
ENSG00000107371homo_sapiensENSP0000032304694.909192heterocephalus_glaber_femaleENSHGLP0000000331495.255592.3358
ENSG00000107371homo_sapiensENSP0000032304697.818297.8182rhinopithecus_bietiENSRBIP0000000606297.818297.8182
ENSG00000107371homo_sapiensENSP0000032304693.818291.6364canis_lupus_dingoENSCAFP0002002268393.478391.3043
ENSG00000107371homo_sapiensENSP0000032304694.545592.3636sciurus_vulgarisENSSVLP0000502271594.545592.3636
ENSG00000107371homo_sapiensENSP0000032304689.454584.3636phascolarctos_cinereusENSPCIP0000001928591.111185.9259
ENSG00000107371homo_sapiensENSP000003230468482.1818procavia_capensisENSPCAP0000000555295.454593.3884
ENSG00000107371homo_sapiensENSP0000032304692.363686.9091nannospalax_galiliENSNGAP0000001721094.776189.1791
ENSG00000107371homo_sapiensENSP000003230469694.1818bos_grunniensENSBGRP000000026949694.1818
ENSG00000107371homo_sapiensENSP0000032304694.909191.6364chinchilla_lanigeraENSCLAP0000002430994.909191.6364
ENSG00000107371homo_sapiensENSP000003230469694.5455cervus_hanglu_yarkandensisENSCHYP0000003695295.652294.2029
ENSG00000107371homo_sapiensENSP0000032304694.181892catagonus_wagneriENSCWAP0000002288694.525692.3358
ENSG00000107371homo_sapiensENSP0000032304694.909192.3636ictidomys_tridecemlineatusENSSTOP0000000884094.909192.3636
ENSG00000107371homo_sapiensENSP0000032304694.181893.0909otolemur_garnettiiENSOGAP0000000918293.501892.4188
ENSG00000107371homo_sapiensENSP0000032304696.727396cebus_imitatorENSCCAP0000000169885.806485.1613
ENSG00000107371homo_sapiensENSP0000032304694.909192.3636urocitellus_parryiiENSUPAP0001002101894.909192.3636
ENSG00000107371homo_sapiensENSP0000032304695.636493.8182moschus_moschiferusENSMMSP0000001176695.636493.8182
ENSG00000107371homo_sapiensENSP0000032304697.818297.8182rhinopithecus_roxellanaENSRROP0000001863797.818297.8182
ENSG00000107371homo_sapiensENSP0000032304691.636486.9091mus_pahariMGP_PahariEiJ_P005792391.970887.2263
ENSG00000107371homo_sapiensENSP0000032304696.727395.6364propithecus_coquereliENSPCOP0000003102996.727395.6364
ENSG00000107371homo_sapiensENSP0000032304649.090931.6364caenorhabditis_elegansF59C6.4.159.734538.4956
ENSG00000107371homo_sapiensENSP0000032304656.727336drosophila_melanogasterFBpp031155567.241442.6724
ENSG00000107371homo_sapiensENSP0000032304658.181838.1818ciona_intestinalisENSCINP0000003319966.3943.5685
ENSG00000107371homo_sapiensENSP0000032304667.272749.8182petromyzon_marinusENSPMAP0000000897272.834653.937
ENSG00000107371homo_sapiensENSP000003230466045.0909eptatretus_burgeriENSEBUP0000002577768.7551.6667
ENSG00000107371homo_sapiensENSP0000032304664.727354.1818callorhinchus_miliiENSCMIP0000003846945.994838.5013
ENSG00000107371homo_sapiensENSP0000032304672.727361.0909latimeria_chalumnaeENSLACP0000000656881.967268.8525
ENSG00000107371homo_sapiensENSP000003230467256.7273lepisosteus_oculatusENSLOCP0000001409476.744260.4651
ENSG00000107371homo_sapiensENSP0000032304670.545556clupea_harengusENSCHAP0000005023380.497963.9004
ENSG00000107371homo_sapiensENSP0000032304670.545554.5455danio_rerioENSDARP0000013744078.542560.7287
ENSG00000107371homo_sapiensENSP0000032304670.545554.5455danio_rerioENSDARP0000013897278.542560.7287
ENSG00000107371homo_sapiensENSP0000032304648.727338.5455carassius_auratusENSCARP0000013183579.761963.0952
ENSG00000107371homo_sapiensENSP0000032304670.181856carassius_auratusENSCARP0000005333078.775562.8571
ENSG00000107371homo_sapiensENSP0000032304671.636458.9091astyanax_mexicanusENSAMXP0000004444780.408266.1225
ENSG00000107371homo_sapiensENSP000003230467255.6364ictalurus_punctatusENSIPUP0000001388380.487862.1951
ENSG00000107371homo_sapiensENSP0000032304672.363657.0909esox_luciusENSELUP0000004462481.89364.6091
ENSG00000107371homo_sapiensENSP0000032304670.545556.7273electrophorus_electricusENSEEEP0000003091179.183763.6735
ENSG00000107371homo_sapiensENSP0000032304671.636457.0909oncorhynchus_kisutchENSOKIP0000506575171.636457.0909
ENSG00000107371homo_sapiensENSP0000032304671.272756.3636oncorhynchus_mykissENSOMYP0000008239476.862760.7843
ENSG00000107371homo_sapiensENSP0000032304671.636456.7273salmo_salarENSSSAP0000004041880.737763.9344
ENSG00000107371homo_sapiensENSP0000032304671.636457.0909salmo_truttaENSSTUP0000003415781.742765.1452
ENSG00000107371homo_sapiensENSP0000032304670.181854.5455gadus_morhuaENSGMOP0000000533279.098461.4754
ENSG00000107371homo_sapiensENSP0000032304669.818254.1818fundulus_heteroclitusENSFHEP0000000739263.787449.5017
ENSG00000107371homo_sapiensENSP0000032304669.454554.1818poecilia_reticulataENSPREP0000001697469.963454.5788
ENSG00000107371homo_sapiensENSP0000032304667.636452.3636xiphophorus_maculatusENSXMAP0000001514375.918458.7755
ENSG00000107371homo_sapiensENSP0000032304669.454553.0909oryzias_latipesENSORLP0000003301876.458.4
ENSG00000107371homo_sapiensENSP0000032304670.181854.1818cyclopterus_lumpusENSCLMP0000503547279.098461.0656
ENSG00000107371homo_sapiensENSP0000032304672.363656.3636oreochromis_niloticusENSONIP0000006560781.557463.5246
ENSG00000107371homo_sapiensENSP0000032304671.636454.9091haplochromis_burtoniENSHBUP0000003400880.737761.8852
ENSG00000107371homo_sapiensENSP0000032304671.636454.9091astatotilapia_callipteraENSACLP0000002256780.737761.8852
ENSG00000107371homo_sapiensENSP0000032304651.272742.1818lates_calcariferENSLCAP0001002174364.97753.4562
ENSG00000107371homo_sapiensENSP0000032304670.545553.4545lates_calcariferENSLCAP0001000024868.070251.5789
ENSG00000107371homo_sapiensENSP0000032304675.636461.0909xenopus_tropicalisENSXETP0000002859983.267.2
ENSG00000107371homo_sapiensENSP0000032304681.090972.3636chrysemys_picta_belliiENSCPBP0000000944076.632368.3849
ENSG00000107371homo_sapiensENSP0000032304677.454566.9091sphenodon_punctatusENSSPUP0000001253482.239471.0425
ENSG00000107371homo_sapiensENSP0000032304672.727362.5455crocodylus_porosusENSCPRP0000501452052.910145.5026
ENSG00000107371homo_sapiensENSP0000032304679.272768.7273laticauda_laticaudataENSLLTP0000000004482.264271.3208
ENSG00000107371homo_sapiensENSP0000032304680.727370.1818notechis_scutatusENSNSUP0000000798077.351967.2474
ENSG00000107371homo_sapiensENSP0000032304679.272769.8182pseudonaja_textilisENSPTXP0000001536882.264272.4528
ENSG00000107371homo_sapiensENSP000003230468067.6364anas_platyrhynchos_platyrhynchosENSAPLP0000000553981.784469.145
ENSG00000107371homo_sapiensENSP0000032304677.818266.9091gallus_gallusENSGALP0001001489782.307770.7692
ENSG00000107371homo_sapiensENSP0000032304663.272755.2727meleagris_gallopavoENSMGAP0000000037970.445361.5385
ENSG00000107371homo_sapiensENSP0000032304666.909157.0909serinus_canariaENSSCAP0000000367376.666765.4167
ENSG00000107371homo_sapiensENSP0000032304679.636467.6364parus_majorENSPMJP0000000415585.546972.6562
ENSG00000107371homo_sapiensENSP0000032304681.818270.1818anolis_carolinensisENSACAP0000002766085.551373.384
ENSG00000107371homo_sapiensENSP0000032304671.272754.9091neolamprologus_brichardiENSNBRP0000000017380.327961.8852
ENSG00000107371homo_sapiensENSP000003230465242.5455neolamprologus_brichardiENSNBRP0000001955778.571464.2857
ENSG00000107371homo_sapiensENSP0000032304680.363670.5455naja_najaENSNNAP0000000892883.396273.2076
ENSG00000107371homo_sapiensENSP000003230468069.0909podarcis_muralisENSPMRP0000000455380.586169.5971
ENSG00000107371homo_sapiensENSP0000032304665.818254.5455geospiza_fortisENSGFOP0000002218277.021363.8298
ENSG00000107371homo_sapiensENSP0000032304669.454558.1818taeniopygia_guttataENSTGUP0000003755549.739641.6667
ENSG00000107371homo_sapiensENSP0000032304669.090954.9091erpetoichthys_calabaricusENSECRP0000003377479.831963.4454
ENSG00000107371homo_sapiensENSP0000032304670.909153.8182kryptolebias_marmoratusENSKMAP0000002469579.91860.6557
ENSG00000107371homo_sapiensENSP0000032304680.727371.2727salvator_merianaeENSSMRP0000001088585.057575.0958
ENSG00000107371homo_sapiensENSP0000032304661.818245.4545oryzias_javanicusENSOJAP0000004013570.539451.8672
ENSG00000107371homo_sapiensENSP0000032304671.636456amphilophus_citrinellusENSACIP0000002952580.737763.1148
ENSG00000107371homo_sapiensENSP000003230466850.5455dicentrarchus_labraxENSDLAP0000500542376.954757.2016
ENSG00000107371homo_sapiensENSP0000032304669.090954.1818amphiprion_perculaENSAPEP0000002599369.090954.1818
ENSG00000107371homo_sapiensENSP0000032304668.727352.7273oryzias_sinensisENSOSIP0000001283775.658
ENSG00000107371homo_sapiensENSP0000032304657.818252.3636pelodiscus_sinensisENSPSIP0000000630394.642985.7143
ENSG00000107371homo_sapiensENSP0000032304680.727372.3636gopherus_evgoodeiENSGEVP0000502621474.247566.5552
ENSG00000107371homo_sapiensENSP0000032304679.636471.6364chelonoidis_abingdoniiENSCABP0000002536683.587875.1908
ENSG00000107371homo_sapiensENSP0000032304670.181853.8182seriola_dumeriliENSSDUP0000002183479.098460.6557
ENSG00000107371homo_sapiensENSP0000032304670.909153.4545cottoperca_gobioENSCGOP0000001479474.144555.8935
ENSG00000107371homo_sapiensENSP0000032304661.454554.5455struthio_camelus_australisENSSCUP0000002010377.880269.1244
ENSG00000107371homo_sapiensENSP0000032304680.363668anser_brachyrhynchusENSABRP0000000142883.082770.3008
ENSG00000107371homo_sapiensENSP0000032304670.545553.0909gasterosteus_aculeatusENSGACP0000002156278.861859.3496
ENSG00000107371homo_sapiensENSP0000032304671.272753.4545cynoglossus_semilaevisENSCSEP0000000867580.327960.2459
ENSG00000107371homo_sapiensENSP0000032304669.090953.8182poecilia_formosaENSPFOP0000000287969.597154.2125
ENSG00000107371homo_sapiensENSP0000032304671.272754.9091myripristis_murdjanENSMMDP0000505338980.327961.8852
ENSG00000107371homo_sapiensENSP0000032304654.181842.5455sander_luciopercaENSSLUP0000004196373.762457.9208
ENSG00000107371homo_sapiensENSP0000032304670.545554.1818sander_luciopercaENSSLUP0000002028679.508261.0656
ENSG00000107371homo_sapiensENSP0000032304677.090966.5455strigops_habroptilaENSSHBP0000500953183.464672.0472
ENSG00000107371homo_sapiensENSP0000032304669.818254.9091amphiprion_ocellarisENSAOCP0000001317169.818254.9091
ENSG00000107371homo_sapiensENSP0000032304681.818273.4545terrapene_carolina_triunguisENSTMTP0000000832665.217458.5507
ENSG00000107371homo_sapiensENSP0000032304671.636457.0909hucho_huchoENSHHUP0000006203071.636457.0909
ENSG00000107371homo_sapiensENSP0000032304669.454553.8182betta_splendensENSBSLP0000001307174.609457.8125
ENSG00000107371homo_sapiensENSP0000032304671.272757.4545pygocentrus_nattereriENSPNAP000000045268064.4898
ENSG00000107371homo_sapiensENSP0000032304669.454553.0909anabas_testudineusENSATEP0000002748178.278759.8361
ENSG00000107371homo_sapiensENSP0000032304642.909127.2727saccharomyces_cerevisiaeYOL142W49.166731.25
ENSG00000107371homo_sapiensENSP0000032304671.636454.5455seriola_lalandi_dorsalisENSSLDP0000002214878.174659.5238
ENSG00000107371homo_sapiensENSP0000032304666.545552labrus_bergyltaENSLBEP0000002650374.693958.3673
ENSG00000107371homo_sapiensENSP0000032304671.636454.9091pundamilia_nyerereiENSPNYP0000000318780.737761.8852
ENSG00000107371homo_sapiensENSP0000032304672.363655.6364mastacembelus_armatusENSMAMP0000002097081.557462.7049
ENSG00000107371homo_sapiensENSP0000032304670.181855.2727stegastes_partitusENSSPAP0000000722079.098462.2951
ENSG00000107371homo_sapiensENSP0000032304671.636457.0909oncorhynchus_tshawytschaENSOTSP0000506769471.376856.8841
ENSG00000107371homo_sapiensENSP0000032304668.363652.7273acanthochromis_polyacanthusENSAPOP0000001591377.049259.4262
ENSG00000107371homo_sapiensENSP0000032304663.636453.4545aquila_chrysaetos_chrysaetosENSACCP0002001861746.791439.3048
ENSG00000107371homo_sapiensENSP0000032304669.090953.8182nothobranchius_furzeriENSNFUP0001500391876.612959.6774
ENSG00000107371homo_sapiensENSP0000032304669.454554.5455cyprinodon_variegatusENSCVAP0000002233478.278761.4754
ENSG00000107371homo_sapiensENSP0000032304670.545554.5455denticeps_clupeoidesENSDCDP0000004924580.497962.2407
ENSG00000107371homo_sapiensENSP0000032304669.818252.7273larimichthys_croceaENSLCRP0000500306878.688559.4262
ENSG00000107371homo_sapiensENSP0000032304667.636452.3636takifugu_rubripesENSTRUP0000005802774.457.6
ENSG00000107371homo_sapiensENSP0000032304661.454553.4545ficedula_albicollisENSFALP0000000715593.370281.2155
ENSG00000107371homo_sapiensENSP0000032304670.545554.5455hippocampus_comesENSHCOP0000001072978.861860.9756
ENSG00000107371homo_sapiensENSP0000032304671.272755.6364cyprinus_carpio_carpioENSCCRP000000172968062.449
ENSG00000107371homo_sapiensENSP0000032304670.545555.6364cyprinus_carpio_carpioENSCCRP0000000917379.183762.449
ENSG00000107371homo_sapiensENSP0000032304678.909167.6364coturnix_japonicaENSCJPP0000501524083.783871.8147
ENSG00000107371homo_sapiensENSP0000032304669.090953.8182poecilia_latipinnaENSPLAP0000000003169.597154.2125
ENSG00000107371homo_sapiensENSP0000032304661.818249.0909sinocyclocheilus_grahamiENSSGRP0000001348576.233260.5381
ENSG00000107371homo_sapiensENSP0000032304670.909156.7273sinocyclocheilus_grahamiENSSGRP0000007380170.909156.7273
ENSG00000107371homo_sapiensENSP0000032304671.636454.9091maylandia_zebraENSMZEP0000500922680.737761.8852
ENSG00000107371homo_sapiensENSP0000032304670.909152tetraodon_nigroviridisENSTNIP0000000912178.62957.6613
ENSG00000107371homo_sapiensENSP0000032304670.545556paramormyrops_kingsleyaeENSPKIP0000001205068.794354.6099
ENSG00000107371homo_sapiensENSP0000032304670.545555.6364scleropages_formosusENSSFOP0001500119281.171564.0167
ENSG00000107371homo_sapiensENSP0000032304676.363662.9091leptobrachium_leishanenseENSLLEP000000060678469.2
ENSG00000107371homo_sapiensENSP0000032304670.181852scophthalmus_maximusENSSMAP0000005557979.098458.6066
ENSG00000107371homo_sapiensENSP0000032304660.363645.0909oryzias_melastigmaENSOMEP0000000915760.805945.4212

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000175enables 3-5-RNA exonuclease activity1NASHomo_sapiens(9606)Function
GO:0000176part_of nuclear exosome (RNase complex)3IBA,IDA,NASHomo_sapiens(9606)Component
GO:0000177part_of cytoplasmic exosome (RNase complex)3IBA,IDA,NASHomo_sapiens(9606)Component
GO:0000178part_of exosome (RNase complex)2IDA,NASHomo_sapiens(9606)Component
GO:0000467involved_in exonucleolytic trimming to generate mature 3-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)1IBAHomo_sapiens(9606)Process
GO:0000791part_of euchromatin1IMPHomo_sapiens(9606)Component
GO:0003723enables RNA binding1IBAHomo_sapiens(9606)Function
GO:0004532NOT enables RNA exonuclease activity1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1IDAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0006364involved_in rRNA processing1IDAHomo_sapiens(9606)Process
GO:0006396involved_in RNA processing1IDAHomo_sapiens(9606)Process
GO:0006401involved_in RNA catabolic process1IDAHomo_sapiens(9606)Process
GO:0034427involved_in nuclear-transcribed mRNA catabolic process, exonucleolytic, 3-51IBAHomo_sapiens(9606)Process
GO:0034475involved_in U4 snRNA 3-end processing1IBAHomo_sapiens(9606)Process
GO:0043928involved_in exonucleolytic catabolism of deadenylated mRNA2IBA,IMPHomo_sapiens(9606)Process
GO:0045006involved_in DNA deamination1IDAHomo_sapiens(9606)Process
GO:0045190involved_in isotype switching1ISSHomo_sapiens(9606)Process
GO:0045830involved_in positive regulation of isotype switching1IEAHomo_sapiens(9606)Process
GO:0071034involved_in CUT catabolic process2IBA,IMPHomo_sapiens(9606)Process
GO:0071035involved_in nuclear polyadenylation-dependent rRNA catabolic process1IBAHomo_sapiens(9606)Process
GO:0071038involved_in nuclear polyadenylation-dependent tRNA catabolic process1IBAHomo_sapiens(9606)Process
GO:0071051involved_in polyadenylation-dependent snoRNA 3-end processing1IBAHomo_sapiens(9606)Process
GO:0101019part_of nucleolar exosome (RNase complex)1NASHomo_sapiens(9606)Component

Expression