Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerCHIKVSARS-COV-OC43FlavivirusesHIVIAVRVSARS-COV-2DengueZika
Drug N.A.
Main interacting RNAs ncRNA
Moonlighting functions N.A.
Localizations Stress granucleP-body
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000105939 Gene ID 56829 Accession 23721
Symbol ZC3HAV1 Alias Full Name
Status Confidence Length 88608 bases Strand Minus strand
Position 7 : 139043515 - 139132122 RNA binding domain PARP
Summary

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000505045 PARP PF00644 1.9e-21 1
ENSP00000242351 PARP PF00644 2.9e-21 1
ENSP00000418385 PARP PF00644 3.5e-21 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
ZC3HAV1-201 ENST00000242351 7177 902aa ENSP00000242351
ZC3HAV1-203 ENST00000464606 4776 1024aa ENSP00000418385
ZC3HAV1-205 ENST00000680309 4268 757aa ENSP00000505045
ZC3HAV1-202 ENST00000460845 1487 264aa ENSP00000420107
ZC3HAV1-204 ENST00000471652 3182 699aa ENSP00000419855

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
47524Intelligence Tests1.0979300E-005-
48279Child Development Disorders, Pervasive5.2169100E-005-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000105939homo_sapiensENSP0000050739021.97810.8669homo_sapiensENSP0000024235119.95579.86696
ENSG00000105939homo_sapiensENSP0000029592434.55120.7002homo_sapiensENSP0000024235125.166315.0776
ENSG00000105939homo_sapiensENSP0000041721423.303812.9794homo_sapiensENSP0000024235117.51669.7561
ENSG00000105939homo_sapiensENSP0000032561816.68298.29268homo_sapiensENSP0000024235118.95799.4235
ENSG00000105939homo_sapiensENSP0000026354950.21433.9515homo_sapiensENSP0000024235139.024426.3858
ENSG00000105939homo_sapiensENSP0000027576654.333338homo_sapiensENSP0000024235118.07112.6386
ENSG00000105939homo_sapiensENSP0000022882049.408328.6982homo_sapiensENSP0000024235118.514410.7539
ENSG00000105939homo_sapiensENSP0000041819415.21387.71793homo_sapiensENSP0000024235130.376915.4102

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000105939homo_sapiensENSP0000024235192.682991.02nomascus_leucogenysENSNLEP0000002979784.359282.8456
ENSG00000105939homo_sapiensENSP0000024235198.447997.3392pan_paniscusENSPPAP0000003247686.718885.7422
ENSG00000105939homo_sapiensENSP0000024235196.895894.7894pongo_abeliiENSPPYP0000002024685.268383.4146
ENSG00000105939homo_sapiensENSP0000024235198.447997.4501pan_troglodytesENSPTRP0000004127986.718885.8398
ENSG00000105939homo_sapiensENSP0000024235198.447997.7827gorilla_gorillaENSGGOP0000000064286.718886.1328
ENSG00000105939homo_sapiensENSP0000024235153.436839.0244sarcophilus_harrisiiENSSHAP0000003058247.070334.375
ENSG00000105939homo_sapiensENSP0000024235162.860353.7694choloepus_hoffmanniENSCHOP0000000405963.210754.0691
ENSG00000105939homo_sapiensENSP0000024235172.94962.0843dasypus_novemcinctusENSDNOP0000002254273.273962.3608
ENSG00000105939homo_sapiensENSP0000024235136.141929.8226erinaceus_europaeusENSEEUP0000001023045.089937.2061
ENSG00000105939homo_sapiensENSP0000024235159.312648.0044echinops_telfairiENSETEP0000000094961.494349.7701
ENSG00000105939homo_sapiensENSP0000024235190.354883.7029callithrix_jacchusENSCJAP0000002410279.745673.8748
ENSG00000105939homo_sapiensENSP0000024235190.465686.3636cercocebus_atysENSCATP0000003498279.454775.852
ENSG00000105939homo_sapiensENSP0000024235192.017788.3592macaca_fascicularisENSMFAP0000004773479.274176.1223
ENSG00000105939homo_sapiensENSP0000024235193.569890.4656macaca_mulattaENSMMUP0000000862493.466290.3654
ENSG00000105939homo_sapiensENSP0000024235187.915784.5898macaca_nemestrinaENSMNEP0000002556278.282375.3208
ENSG00000105939homo_sapiensENSP0000024235192.793889.5787papio_anubisENSPANP0000001804181.578978.7524
ENSG00000105939homo_sapiensENSP0000024235184.811581.0421mandrillus_leucophaeusENSMLEP0000003699079.274675.7513
ENSG00000105939homo_sapiensENSP0000024235165.521155.765tursiops_truncatusENSTTRP0000000572974.339663.2704
ENSG00000105939homo_sapiensENSP0000024235175.38863.6364vulpes_vulpesENSVVUP0000000338672.417561.1289
ENSG00000105939homo_sapiensENSP0000024235168.514455.2106mus_spretusMGP_SPRETEiJ_P007613862.110650.0503
ENSG00000105939homo_sapiensENSP0000024235178.492267.184equus_asinusENSEASP0000501475069.343859.3536
ENSG00000105939homo_sapiensENSP0000024235174.61262.8603capra_hircusENSCHIP0000003137075.448463.565
ENSG00000105939homo_sapiensENSP0000024235161.862551.663loxodonta_africanaENSLAFP0000001168963.62653.1357
ENSG00000105939homo_sapiensENSP0000024235176.718465.4102panthera_leoENSPLOP0000000719967.710457.7299
ENSG00000105939homo_sapiensENSP0000024235176.164165.8537ailuropoda_melanoleucaENSAMEP0000003267467.155458.0645
ENSG00000105939homo_sapiensENSP0000024235174.722862.5277bos_indicus_hybridENSBIXP0000504607975.223262.9464
ENSG00000105939homo_sapiensENSP0000024235167.073256.3193oryctolagus_cuniculusENSOCUP0000001537470.185658.9327
ENSG00000105939homo_sapiensENSP0000024235178.71467.5166equus_caballusENSECAP0000002712367.171257.6159
ENSG00000105939homo_sapiensENSP0000024235175.720664.3016canis_lupus_familiarisENSCAFP0084500797973.36262.2986
ENSG00000105939homo_sapiensENSP0000024235176.718465.2993panthera_pardusENSPPRP0000000084068.043357.9154
ENSG00000105939homo_sapiensENSP0000024235168.625358.4257marmota_marmota_marmotaENSMMMP0000001337676.325564.9815
ENSG00000105939homo_sapiensENSP0000024235177.161966.1863balaenoptera_musculusENSBMSP0001002280677.419466.4071
ENSG00000105939homo_sapiensENSP0000024235173.835961.0865cavia_porcellusENSCPOP0000000694874.082361.2903
ENSG00000105939homo_sapiensENSP0000024235176.607565.4102felis_catusENSFCAP0000002091067.612557.7299
ENSG00000105939homo_sapiensENSP0000024235176.274965.7428ursus_americanusENSUAMP0000001913767.253257.9668
ENSG00000105939homo_sapiensENSP0000024235149.667437.0288monodelphis_domesticaENSMODP0000001721454.567640.6821
ENSG00000105939homo_sapiensENSP0000024235171.840459.3126bison_bison_bisonENSBBBP0000000840965.454554.0404
ENSG00000105939homo_sapiensENSP0000024235176.607566.1863monodon_monocerosENSMMNP0001501312576.777866.3333
ENSG00000105939homo_sapiensENSP0000024235174.390263.1929sus_scrofaENSSSCP0000003692075.055963.7584
ENSG00000105939homo_sapiensENSP0000024235178.270568.5144microcebus_murinusENSMICP0000000281569.147960.5289
ENSG00000105939homo_sapiensENSP0000024235172.838159.867octodon_degusENSODEP0000001808870.721258.127
ENSG00000105939homo_sapiensENSP0000024235165.964552.9933jaculus_jaculusENSJJAP0000001445863.500551.0139
ENSG00000105939homo_sapiensENSP0000024235158.20449.3348ovis_aries_rambouilletENSOARP0002000364876.308164.6802
ENSG00000105939homo_sapiensENSP0000024235176.385865.8537ursus_maritimusENSUMAP0000002114667.350958.0645
ENSG00000105939homo_sapiensENSP0000024235156.54145.5654ochotona_princepsENSOPRP0000000809056.54145.5654
ENSG00000105939homo_sapiensENSP0000024235176.274966.1863delphinapterus_leucasENSDLEP0000002981676.529566.4071
ENSG00000105939homo_sapiensENSP0000024235176.607566.2971physeter_catodonENSPCTP0000500356176.863266.5184
ENSG00000105939homo_sapiensENSP0000024235168.514455.2106mus_caroliMGP_CAROLIEiJ_P007329462.110650.0503
ENSG00000105939homo_sapiensENSP0000024235168.625355.4324mus_musculusENSMUSP0000011055062.148650.2008
ENSG00000105939homo_sapiensENSP0000024235169.955756.8736dipodomys_ordiiENSDORP0000002342365.660853.3819
ENSG00000105939homo_sapiensENSP0000024235174.944662.1951mustela_putorius_furoENSMPUP0000000377466.015654.7852
ENSG00000105939homo_sapiensENSP0000024235182.261676.1641aotus_nancymaaeENSANAP0000001554178.2772.4684
ENSG00000105939homo_sapiensENSP0000024235189.689682.9268saimiri_boliviensis_boliviensisENSSBOP0000002204780.98174.8749
ENSG00000105939homo_sapiensENSP0000024235157.317148.0044vicugna_pacosENSVPAP0000000694362.289252.1687
ENSG00000105939homo_sapiensENSP0000024235188.248383.592chlorocebus_sabaeusENSCSAP0000000477277.507373.4177
ENSG00000105939homo_sapiensENSP0000024235134.368126.9401tupaia_belangeriENSTBEP0000000170438.036829.816
ENSG00000105939homo_sapiensENSP0000024235161.197348.0044mesocricetus_auratusENSMAUP0000000641658.723446.0638
ENSG00000105939homo_sapiensENSP0000024235176.940165.6319phocoena_sinusENSPSNP0000002579877.111165.7778
ENSG00000105939homo_sapiensENSP0000024235176.053263.8581camelus_dromedariusENSCDRP0000500395776.39264.1425
ENSG00000105939homo_sapiensENSP0000024235158.758352.8825carlito_syrichtaENSTSYP0000002484071.045663.941
ENSG00000105939homo_sapiensENSP0000024235167.849256.9845panthera_tigris_altaicaENSPTIP0000000367064.421154.1053
ENSG00000105939homo_sapiensENSP0000024235167.960154.7672rattus_norvegicusENSRNOP0000001878262.487350.3568
ENSG00000105939homo_sapiensENSP0000024235178.935769.4013prolemur_simusENSPSMP0000002821069.463461.0732
ENSG00000105939homo_sapiensENSP0000024235167.516655.8758microtus_ochrogasterENSMOCP0000000547562.333751.5865
ENSG00000105939homo_sapiensENSP0000024235168.957957.6497peromyscus_maniculatus_bairdiiENSPEMP0000001571163.599253.1697
ENSG00000105939homo_sapiensENSP0000024235174.944662.4169bos_mutusENSBMUP0000002303775.194762.6251
ENSG00000105939homo_sapiensENSP0000024235164.966752.6608mus_spicilegusENSMSIP0000003561061.425649.7904
ENSG00000105939homo_sapiensENSP0000024235167.738455.6541cricetulus_griseus_chok1gshdENSCGRP0000101388161.779650.7583
ENSG00000105939homo_sapiensENSP0000024235164.190755.2106pteropus_vampyrusENSPVAP0000001638564.476655.4566
ENSG00000105939homo_sapiensENSP0000024235173.059961.6408myotis_lucifugusENSMLUP0000001098365.955.6
ENSG00000105939homo_sapiensENSP0000024235152.549939.4678vombatus_ursinusENSVURP0001001842645.974834.5296
ENSG00000105939homo_sapiensENSP0000024235174.833764.3016rhinolophus_ferrumequinumENSRFEP0001001076966.111756.8071
ENSG00000105939homo_sapiensENSP0000024235166.40855.3215neovison_visonENSNVIP0000002850363.119152.5817
ENSG00000105939homo_sapiensENSP0000024235174.833762.7494bos_taurusENSBTAP0000002880675.334863.1696
ENSG00000105939homo_sapiensENSP0000024235174.722861.4191heterocephalus_glaber_femaleENSHGLP0000000934374.147460.9461
ENSG00000105939homo_sapiensENSP0000024235188.691885.9202rhinopithecus_bietiENSRBIP0000001331981.218378.6802
ENSG00000105939homo_sapiensENSP0000024235175.942464.4124canis_lupus_dingoENSCAFP0002002851176.280664.6993
ENSG00000105939homo_sapiensENSP0000024235177.05165.8537sciurus_vulgarisENSSVLP0000501928077.56766.2946
ENSG00000105939homo_sapiensENSP0000024235155.099841.1308phascolarctos_cinereusENSPCIP0000002906047.288335.2997
ENSG00000105939homo_sapiensENSP0000024235157.649748.2262procavia_capensisENSPCAP0000001237758.492748.9314
ENSG00000105939homo_sapiensENSP0000024235172.94960.1996nannospalax_galiliENSNGAP0000001578067.280255.5215
ENSG00000105939homo_sapiensENSP0000024235174.944662.5277bos_grunniensENSBGRP0000000426075.194762.7364
ENSG00000105939homo_sapiensENSP0000024235174.833761.9734chinchilla_lanigeraENSCLAP0000000179674.503361.6998
ENSG00000105939homo_sapiensENSP0000024235174.61262.5277cervus_hanglu_yarkandensisENSCHYP0000002463074.944362.8062
ENSG00000105939homo_sapiensENSP0000024235173.392560.7539catagonus_wagneriENSCWAP0000001903074.38261.573
ENSG00000105939homo_sapiensENSP0000024235165.299355.0998ictidomys_tridecemlineatusENSSTOP0000000506873.62562.125
ENSG00000105939homo_sapiensENSP0000024235179.379268.1818otolemur_garnettiiENSOGAP0000000938079.555668.3333
ENSG00000105939homo_sapiensENSP0000024235189.024482.7051cebus_imitatorENSCCAP0000002086878.571472.9941
ENSG00000105939homo_sapiensENSP0000024235175.720664.5233urocitellus_parryiiENSUPAP0001002328675.804764.5949
ENSG00000105939homo_sapiensENSP0000024235173.503361.9734moschus_moschiferusENSMMSP0000000329174.078262.4581
ENSG00000105939homo_sapiensENSP0000024235192.793889.8004rhinopithecus_roxellanaENSRROP0000003775392.588589.6018
ENSG00000105939homo_sapiensENSP0000024235162.638649.2239mus_pahariMGP_PahariEiJ_P004941356.387244.3114
ENSG00000105939homo_sapiensENSP0000024235166.075457.6497propithecus_coquereliENSPCOP0000001806267.041658.4927
ENSG00000105939homo_sapiensENSP0000024235143.569830.5987chrysemys_picta_belliiENSCPBP0000003479255.665739.0935
ENSG00000105939homo_sapiensENSP0000024235124.944618.071sphenodon_punctatusENSSPUP0000000243458.593842.4479
ENSG00000105939homo_sapiensENSP0000024235143.015531.7073crocodylus_porosusENSCPRP0000500217456.477441.6303
ENSG00000105939homo_sapiensENSP0000024235141.130829.49laticauda_laticaudataENSLLTP0000000780354.478739.0602
ENSG00000105939homo_sapiensENSP0000024235141.685129.9335notechis_scutatusENSNSUP0000000826155.13239.5894
ENSG00000105939homo_sapiensENSP0000024235138.913528.0488pseudonaja_textilisENSPTXP0000000234754.587939.3468
ENSG00000105939homo_sapiensENSP0000024235143.45933.0377anas_platyrhynchos_platyrhynchosENSAPLP0000001113954.672241.5621
ENSG00000105939homo_sapiensENSP0000024235143.348131.5965gallus_gallusENSGALP0001003409754.761939.916
ENSG00000105939homo_sapiensENSP0000024235142.682931.3747meleagris_gallopavoENSMGAP0000001464754.378539.9718
ENSG00000105939homo_sapiensENSP0000024235142.017731.153serinus_canariaENSSCAP0000000353648.280335.7962
ENSG00000105939homo_sapiensENSP0000024235134.368124.0576parus_majorENSPMJP0000001361236.729925.7109
ENSG00000105939homo_sapiensENSP0000024235144.124231.3747anolis_carolinensisENSACAP0000002250254.896639.0345
ENSG00000105939homo_sapiensENSP0000024235139.800427.7162naja_najaENSNNAP0000002309056.803839.557
ENSG00000105939homo_sapiensENSP000002423514.545453.54767naja_najaENSNNAP0000002617046.590936.3636
ENSG00000105939homo_sapiensENSP0000024235142.461231.3747podarcis_muralisENSPMRP0000000154842.320431.2707
ENSG00000105939homo_sapiensENSP0000024235135.033325.388geospiza_fortisENSGFOP0000001229346.607733.7758
ENSG00000105939homo_sapiensENSP0000024235136.585427.051taeniopygia_guttataENSTGUP0000001214343.766632.3607
ENSG00000105939homo_sapiensENSP0000024235142.904730.1552salvator_merianaeENSSMRP0000001032855.128238.7464
ENSG00000105939homo_sapiensENSP0000024235113.52558.98004amphilophus_citrinellusENSACIP0000000950751.476834.1772
ENSG00000105939homo_sapiensENSP0000024235143.569831.8182pelodiscus_sinensisENSPSIP0000001244343.377531.6777
ENSG00000105939homo_sapiensENSP0000024235143.569830.5987gopherus_evgoodeiENSGEVP0000500085056.956540
ENSG00000105939homo_sapiensENSP0000024235143.902430.8204chelonoidis_abingdoniiENSCABP0000002911358.493441.0635
ENSG00000105939homo_sapiensENSP0000024235137.472326.4967struthio_camelus_australisENSSCUP0000001491155.500839.2447
ENSG00000105939homo_sapiensENSP0000024235119.844813.8581anser_brachyrhynchusENSABRP0000002213361.092242.6621
ENSG00000105939homo_sapiensENSP0000024235114.96678.75832sander_luciopercaENSSLUP0000003371955.10232.2449
ENSG00000105939homo_sapiensENSP0000024235143.348132.0399strigops_habroptilaENSSHBP0000500662257.247442.3133
ENSG00000105939homo_sapiensENSP0000024235143.45930.7095terrapene_carolina_triunguisENSTMTP0000003196556.811640.1449
ENSG00000105939homo_sapiensENSP0000024235143.902431.3747aquila_chrysaetos_chrysaetosENSACCP0002001226456.090740.085
ENSG00000105939homo_sapiensENSP0000024235142.572131.153ficedula_albicollisENSFALP0000001693340.807729.8618
ENSG00000105939homo_sapiensENSP0000024235141.463430.3769coturnix_japonicaENSCJPP0000502004452.38138.3754
ENSG00000105939homo_sapiensENSP0000024235114.07989.09091scleropages_formosusENSSFOP0001501656746.181829.8182

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003950NOT enables NAD+ ADP-ribosyltransferase activity1IMPHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus1IBAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0009615involved_in response to virus2IBA,IDAHomo_sapiens(9606)Process
GO:0032481involved_in positive regulation of type I interferon production1IBAHomo_sapiens(9606)Process
GO:0045071involved_in negative regulation of viral genome replication1IDAHomo_sapiens(9606)Process
GO:0045087involved_in innate immune response1IEAHomo_sapiens(9606)Process
GO:0045296enables cadherin binding1HDAHomo_sapiens(9606)Function
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function
GO:0051607involved_in defense response to virus1IEAHomo_sapiens(9606)Process
GO:0061014involved_in positive regulation of mRNA catabolic process2IBA,IDAHomo_sapiens(9606)Process
GO:0070212NOT involved_in protein poly-ADP-ribosylation1IMPHomo_sapiens(9606)Process
GO:0070403NOT enables NAD+ binding1IMPHomo_sapiens(9606)Function
GO:1990404NOT enables NAD+-protein ADP-ribosyltransferase activity1IDAHomo_sapiens(9606)Function

Expression